| Item Type | Name |
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Academic Article
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Cellular immunotherapy for high-grade glioma.
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Academic Article
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Expansion of T cells targeting multiple antigens of cytomegalovirus, Epstein-Barr virus and adenovirus to provide broad antiviral specificity after stem cell transplantation.
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Academic Article
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Immunotherapy for osteosarcoma: genetic modification of T cells overcomes low levels of tumor antigen expression.
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Academic Article
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piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies.
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Academic Article
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HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors.
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Academic Article
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Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation.
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Academic Article
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PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor.
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Academic Article
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In vivo expansion of LMP 1- and 2-specific T-cells in a patient who received donor-derived EBV-specific T-cells after allogeneic stem cell transplantation.
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Concept
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Receptors, Antigen
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Concept
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Receptors, Antigen, T-Cell, alpha-beta
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Concept
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Receptors, Antigen, T-Cell
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Concept
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T-Cell Antigen Receptor Specificity
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Academic Article
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Antitumor effects of chimeric receptor engineered human T cells directed to tumor stroma.
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Academic Article
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TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy.
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Academic Article
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Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma.
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Academic Article
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Design and development of therapies using chimeric antigen receptor-expressing T cells.
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Academic Article
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A vaccine that co-targets tumor cells and cancer associated fibroblasts results in enhanced antitumor activity by inducing antigen spreading.
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Academic Article
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CAR T cells for solid tumors: armed and ready to go?
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Academic Article
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Complementation of antigen-presenting cells to generate T lymphocytes with broad target specificity.
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Academic Article
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T cells redirected to interleukin-13Ra2 with interleukin-13 mutein--chimeric antigen receptors have anti-glioma activity but also recognize interleukin-13Ra1.
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Academic Article
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Toward immunotherapy with redirected T cells in a large animal model: ex vivo activation, expansion, and genetic modification of canine T cells.
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Academic Article
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Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma.
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Academic Article
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Characterization and Functional Analysis of scFv-based Chimeric Antigen Receptors to Redirect T Cells to IL13Ra2-positive Glioma.
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Academic Article
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Tandem CAR T cells targeting HER2 and IL13Ra2 mitigate tumor antigen escape.
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Academic Article
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Redirecting T Cells to Glypican-3 with 4-1BB Zeta Chimeric Antigen Receptors Results in Th1 Polarization and Potent Antitumor Activity.
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Academic Article
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Man's Best Friend: Utilizing Naturally Occurring Tumors in Dogs to Improve Chimeric Antigen Receptor T-cell Therapy for Human Cancers.
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Academic Article
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Armed Oncolytic Adenovirus-Expressing PD-L1 Mini-Body Enhances Antitumor Effects of Chimeric Antigen Receptor T Cells in Solid Tumors.
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Academic Article
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HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial.
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Academic Article
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Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Ra2-CAR T Cells but Results in Antigen Loss Variants.
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Academic Article
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Inducible Activation of MyD88 and CD40 in CAR T Cells Results in Controllable and Potent Antitumor Activity in Preclinical Solid Tumor Models.
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Academic Article
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Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells.
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Academic Article
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Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1.
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Academic Article
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Adenovirotherapy Delivering Cytokine and Checkpoint Inhibitor Augments CAR T Cells against Metastatic Head and Neck Cancer.
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Academic Article
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HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice.
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Academic Article
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CD28 and 41BB Costimulation Enhances the Effector Function of CD19-Specific Engager T Cells.
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Academic Article
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Adoptive Transfer of IL13Ra2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma.
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Academic Article
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The Landscape of CAR T Cells Beyond Acute Lymphoblastic Leukemia for Pediatric Solid Tumors.
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Academic Article
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NK Cells Expressing a Chimeric Activating Receptor Eliminate MDSCs and Rescue Impaired CAR-T Cell Activity against Solid Tumors.
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Academic Article
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Chimeric Antigen Receptor Signaling Domains Differentially Regulate Proliferation and Native T Cell Receptor Function in Virus-Specific T Cells.
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Grant
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Reprogramming of T cells for the Treatment of Melanoma
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Grant
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IL13Ra2 targeted T-cell therapy for glioma
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Academic Article
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Peripheral T cell cytotoxicity predicts T cell function in the tumor microenvironment.
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Academic Article
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Engineering for Success: Approaches to Improve Chimeric Antigen Receptor T?Cell Therapy for Solid Tumors.
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Academic Article
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Genetically Modified T-Cell Therapy for Osteosarcoma: Into the Roaring 2020s.
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Academic Article
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The Art and Science of Selecting a CD123-Specific Chimeric Antigen Receptor for Clinical Testing.
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Academic Article
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Preventing Ubiquitination Improves CAR T Cell Therapy via 'CAR Merry-Go-Around'.
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Academic Article
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Chimeric Antigen Receptor-modified T cells targeting EphA2 for the immunotherapy of paediatric bone tumours.
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Academic Article
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CAR T Cell Therapy for Solid Tumors: Bright Future or Dark Reality?
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Academic Article
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MyD88/CD40 signaling retains CAR T cells in a less differentiated state.
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Academic Article
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Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS after allogeneic transplant.
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Academic Article
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A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function.
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Academic Article
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Selectively targeting myeloid-derived suppressor cells through TRAIL receptor 2 to enhance the efficacy of CAR T cell therapy for treatment of breast cancer.
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Academic Article
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Paediatric Strategy Forum for medicinal product development of chimeric antigen receptor T-cells in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
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Academic Article
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CD19-CAR T?cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia.
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Academic Article
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Impact of High Disease Burden on Survival in Pediatric Patients with B-ALL Treated with Tisagenlecleucel.
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Academic Article
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Development of a cGMP-compliant process to manufacture donor-derived, CD45RA-depleted memory CD19-CAR T cells.
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Academic Article
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A Costimulatory CAR Improves TCR-based Cancer Immunotherapy.
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Academic Article
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CAR T?cell therapy for solid tumors: Fatal attraction requires adhesion.
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Academic Article
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Common Trajectories of Highly Effective CD19-Specific CAR T Cells Identified by Endogenous T-cell Receptor Lineages.
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Academic Article
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Engineering naturally occurring CD7- T cells for the immunotherapy of hematological malignancies.
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Academic Article
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A tour de force provides novel insights into CD19-CAR T?cell resistance mechanisms.
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Academic Article
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RASA2 ablation in T cells boosts antigen sensitivity and long-term function.
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Academic Article
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CD19 CAR T-cell therapy demonstrates activity against extramedullary disease in pediatric patients with B-ALL.
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Academic Article
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Preparation of cryopreserved chimeric antigen receptor T cells for the locoreogional delivery to the neural axis.
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Academic Article
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INSPIRED Symposium Part 4B: Chimeric Antigen Receptor T Cell Correlative Studies-Established Findings and Future Priorities.
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Academic Article
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Cytokine Modification of Adoptive Chimeric Antigen Receptor Immunotherapy for Glioblastoma.
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Academic Article
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DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T?cell responses that potentiate cell therapy for fibrolamellar carcinoma.
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Academic Article
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Acute kidney injury following treatment with CD19-specific CAR T-cell therapy in children, adolescent, and young adult patients with B-cell acute lymphoblastic leukemia.
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Academic Article
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Chimeric antigen receptor T-cell therapy in childhood acute myeloid leukemia: how far are we from a clinical application?
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