Item Type | Name |
Concept
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Isocitrate Dehydrogenase
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Academic Article
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Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia.
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Academic Article
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Lack of association of IDH1, IDH2 and DNMT3A mutations with outcome in older patients with acute myeloid leukemia treated with hypomethylating agents.
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Academic Article
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Characteristics, clinical outcome, and prognostic significance of IDH mutations in AML.
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Academic Article
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Targeting Isocitrate Dehydrogenase (IDH) in cancer
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Academic Article
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Isocitrate dehydrogenase mutations in myeloid malignancies
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Academic Article
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Targeting isocitrate dehydrogenase (IDH) in cancer.
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Academic Article
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Evidence for Clinical Differentiation and Differentiation Syndrome in Patients With Acute Myeloid Leukemia and IDH1 Mutations Treated With the Targeted Mutant IDH1 Inhibitor, AG-120.
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Academic Article
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Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.
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Academic Article
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Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia.
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Academic Article
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Novel Therapeutics in Acute Myeloid Leukemia.
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Academic Article
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Targeting IDH1 and IDH2 Mutations in Acute Myeloid Leukemia.
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Academic Article
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The role of IDH mutations in acute myeloid leukemia.
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Academic Article
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Enasidenib for patients with relapsed acute myeloid leukemia and the IDH2 mutation.
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Academic Article
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Clinical experience with the BCL2-inhibitor venetoclax in combination therapy for relapsed and refractory acute myeloid leukemia and related myeloid malignancies.
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Academic Article
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Differentiation Syndrome Associated With Enasidenib, a Selective Inhibitor of Mutant Isocitrate Dehydrogenase 2: Analysis of a Phase 1/2 Study.
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Academic Article
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Characterization of IDH1 p.R132H Mutant Clones Using Mutation-specific Antibody in Myeloid Neoplasms.
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Academic Article
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Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.
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Academic Article
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Persistent IDH1/2 mutations in remission can predict relapse in patients with acute myeloid leukemia.
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Academic Article
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Ivosidenib in IDH1-Mutated Acute Myeloid Leukemia.
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Academic Article
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SOHO State of the Art Update and Next Questions: IDH Therapeutic Targeting in AML.
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Academic Article
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Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib.
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Academic Article
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Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia.
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Academic Article
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Acute Myeloid Leukemia: from Mutation Profiling to Treatment Decisions.
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Academic Article
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How I treat acute myeloid leukemia in the era of new drugs.
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Academic Article
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Single-agent and combination biologics in acute myeloid leukemia.
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Academic Article
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Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.
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Academic Article
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Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial.
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Academic Article
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Clinical pharmacokinetics and pharmacodynamics of ivosidenib in patients with advanced hematologic malignancies with an IDH1 mutation.
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Academic Article
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Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML.
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Academic Article
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Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results.
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Academic Article
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Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study.
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Academic Article
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Outcome of patients with IDH1/2-mutated post-myeloproliferative neoplasm AML in the era of IDH inhibitors.
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Academic Article
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Clinical characteristics and outcomes in patients with acute myeloid leukemia with concurrent FLT3-ITD and IDH mutations.
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Academic Article
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Mutant Isocitrate Dehydrogenase 1 Inhibitor Ivosidenib in Combination With Azacitidine for Newly Diagnosed Acute Myeloid Leukemia.
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Academic Article
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Decitabine and venetoclax for IDH1/2-mutated acute myeloid leukemia.
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Academic Article
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Differentiation syndrome with lower-intensity treatments for acute myeloid leukemia.
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Academic Article
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Outcomes of patients with IDH1-mutant relapsed or refractory acute myeloid leukemia receiving ivosidenib who proceeded to hematopoietic stem cell transplant.
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Academic Article
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Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia.
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Academic Article
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Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia.
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Academic Article
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Acute myeloid leukemia with IDH1 and IDH2 mutations: 2021 treatment algorithm.
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Academic Article
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Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial.
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Academic Article
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A phase 1 study of IDH305 in patients with IDH1R132-mutant acute myeloid leukemia or myelodysplastic syndrome.
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Academic Article
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Combining Isocitrate Dehydrogenase Inhibitors With Existing Regimens in Acute Myeloid Leukemia: An Evolving Treatment Landscape.
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Academic Article
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Efficacy and safety of enasidenib and azacitidine combination in patients with IDH2 mutated acute myeloid leukemia and not eligible for intensive chemotherapy.
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Academic Article
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Impact of Venetoclax and Azacitidine in Treatment-Na?ve Patients with Acute Myeloid Leukemia and IDH1/2 Mutations.
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Academic Article
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Enasidenib vs conventional care in older patients with late-stage mutant-IDH2 relapsed/refractory AML: a randomized phase 3 trial.
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Academic Article
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Targeted therapy with the mutant IDH2 inhibitor enasidenib for high-risk IDH2-mutant myelodysplastic syndrome.
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Academic Article
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Contemporary outcomes in IDH-mutated acute myeloid leukemia: The impact of co-occurring NPM1 mutations and venetoclax-based treatment.
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Academic Article
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A Phase Ib/II Study of Ivosidenib with Venetoclax ? Azacitidine in IDH1-Mutated Myeloid Malignancies.
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Academic Article
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IDH2 mutations in acute myeloid leukemia.
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Academic Article
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Response patterns and impact of MRD in patients with IDH1/2-mutated AML treated with venetoclax and hypomethylating agents.
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