AMYCOURTNEYAMY COURTNEY8141COURTNEY, AMYAssistant Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:orcidIdORCID idvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 156560417291642Manuri PR, Nehete B, Nehete PN, Reisenauer R, Wardell S, Courtney AN, Gambhira R, Lomada D, Chopra AK, Sastry KJVaccineIntranasal immunization with synthetic peptides corresponding to the E6 and E7 oncoproteins of human papillomavirus type 16 induces systemic and mucosal cellular immune responses and tumor protection. Vaccine. 2007 Apr 30; 25(17):3302-10.Vaccine2007-01-24T00:00:002007Intranasal immunization with synthetic peptides corresponding to the E6 and E7 oncoproteins of human papillomavirus type 16 induces systemic and mucosal cellular immune responses and tumor protection.19200815Thapa P, Zhang G, Xia C, Gelbard A, Overwijk WW, Liu C, Hwu P, Chang DZ, Courtney A, Sastry JK, Wang PG, Li C, Zhou DVaccineNanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy. Vaccine. 2009 May 26; 27(25-26):3484-8.Vaccine2009-02-05T00:00:002009Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy.19200849Courtney AN, Nehete PN, Nehete BP, Thapa P, Zhou D, Sastry KJVaccineAlpha-galactosylceramide is an effective mucosal adjuvant for repeated intranasal or oral delivery of HIV peptide antigens. Vaccine. 2009 May 26; 27(25-26):3335-41.Vaccine2009-02-05T00:00:002009Alpha-galactosylceramide is an effective mucosal adjuvant for repeated intranasal or oral delivery of HIV peptide antigens.19805372Fontenot D, He H, Hanabuchi S, Nehete PN, Zhang M, Chang M, Nehete B, Wang YH, Wang YH, Ma ZM, Lee HC, Ziegler SF, Courtney AN, Miller CJ, Sun SC, Liu YJ, Sastry KJProceedings of the National Academy of Sciences of the United States of AmericaTSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells. Proc Natl Acad Sci U S A. 2009 Sep 29; 106(39):16776-81.Proc Natl Acad Sci U S A2009-09-21T00:00:002009TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells.20414189He H, Courtney AN, Wieder E, Sastry KJJournal of visualized experiments : JoVEMulticolor flow cytometry analyses of cellular immune response in rhesus macaques. J Vis Exp. 2010 Apr 22; (38).J Vis Exp2010-04-22T00:00:002010Multicolor flow cytometry analyses of cellular immune response in rhesus macaques.21818755Courtney AN, Thapa P, Singh S, Wishahy AM, Zhou D, Sastry JEuropean journal of immunologyIntranasal but not intravenous delivery of the adjuvant a-galactosylceramide permits repeated stimulation of natural killer T cells in the lung. Eur J Immunol. 2011 Nov; 41(11):3312-22.Eur J Immunol2011-09-19T00:00:002011Intranasal but not intravenous delivery of the adjuvant a-galactosylceramide permits repeated stimulation of natural killer T cells in the lung.25049283Heczey A, Liu D, Tian G, Courtney AN, Wei J, Marinova E, Gao X, Guo L, Yvon E, Hicks J, Liu H, Dotti G, Metelitsa LSBloodInvariant NKT cells with chimeric antigen receptor provide a novel platform for safe and effective cancer immunotherapy. Blood. 2014 Oct 30; 124(18):2824-33.Blood2014-07-21T00:00:002014Invariant NKT cells with chimeric antigen receptor provide a novel platform for safe and effective cancer immunotherapy.25213323Xu X, Hegazy WA, Guo L, Gao X, Courtney AN, Kurbanov S, Liu D, Tian G, Manuel ER, Diamond DJ, Hensel M, Metelitsa LSCancer researchEffective cancer vaccine platform based on attenuated salmonella and a type III secretion system. Cancer Res. 2014 Nov 01; 74(21):6260-70.Cancer Res2014-09-11T00:00:002014Effective cancer vaccine platform based on attenuated salmonella and a type III secretion system.XINXUXIN XU8386XU, XIN0000-0002-9485-8782Assistant ProfessorLymphoma-MyelomaMD AndersonJAGANNADHA KSASTRYJAGANNADHA K SASTRY8499SASTRY, JAGANNADHA KProfessorSATTVA SNEELAPUSATTVA S NEELAPU9154NEELAPU, SATTVA SAssociate Professor27183388Tian G, Courtney AN, Jena B, Heczey A, Liu D, Marinova E, Guo L, Xu X, Torikai H, Mo Q, Dotti G, Cooper LJ, Metelitsa LSThe Journal of clinical investigationCD62L+ NKT cells have prolonged persistence and antitumor activity in vivo. J Clin Invest. 2016 06 01; 126(6):2341-55.J Clin Invest2016-05-16T00:00:002016CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo.74Professor10Assistant Professor54Instructor14Associate Professor6Adjunct ProfessorAuthorship 3234442GENGWENTIANGENGWEN TIAN0.000000000000000.000000000000005256TIAN, GENGWEN0000000333912201Instructor22565311Liu D, Song L, Wei J, Courtney AN, Gao X, Marinova E, Guo L, Heczey A, Asgharzadeh S, Kim E, Dotti G, Metelitsa LSThe Journal of clinical investigationIL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity. J Clin Invest. 2012 Jun; 122(6):2221-33.J Clin Invest2012-05-08T00:00:002012IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity.22782839Liu Z, Courtney AN, Metelitsa LS, Bittman RChembiochem : a European journal of chemical biologyC-Glycosphingolipids with an exo-methylene substituent: stereocontrolled synthesis and immunostimulation of mouse and human natural killer T lymphocytes. Chembiochem. 2012 Aug 13; 13(12):1733-7.Chembiochem2012-07-10T00:00:002012C-Glycosphingolipids with an exo-methylene substituent: stereocontrolled synthesis and immunostimulation of mouse and human natural killer T lymphocytes.30111631Ngai H, Tian G, Courtney AN, Ravari SB, Guo L, Liu B, Jin J, Shen ET, Di Pierro EJ, Metelitsa LSJournal of immunology (Baltimore, Md. : 1950)IL-21 Selectively Protects CD62L+ NKT Cells and Enhances Their Effector Functions for Adoptive Immunotherapy. J Immunol. 2018 10 01; 201(7):2141-2153.J Immunol2018-08-15T00:00:002018IL-21 Selectively Protects CD62L+ NKT Cells and Enhances Their Effector Functions for Adoptive Immunotherapy.D008213PhysiologyProcedures49616860.674501Lymphocyte ActivationAuthorship 9343753D000276Chemicals & Drugs2326550.740229Adjuvants, ImmunologicD005699Chemicals & Drugs16340.979719GalactosylceramidesD009447Disorders2546850.639093NeuroblastomaD055611Anatomy581240.860397Natural Killer T-CellsImmunologyDepartment of PediatricsPediatrics-Hem/Onc Cell & Gene TheBaylor College of MedicineLEONIDMETELITSALEONID METELITSA0.000000000000000.000000000000001547METELITSA, LEONIDProfessorCLIONAROONEYCLIONA ROONEY0.000000000000000.000000000000003578ROONEY, CLIONAProfessorANDRASHECZEYANDRAS HECZEY0.000000000000000.000000000000004430HECZEY, ANDRASAssociate ProfessorSTEPHENGOTTSCHALKSTEPHEN GOTTSCHALK0.000000000000000.0000000000000053GOTTSCHALK, STEPHENAdjunct Professor23687340Hsu DM, Agarwal S, Benham A, Coarfa C, Trahan DN, Chen Z, Stowers PN, Courtney AN, Lakoma A, Barbieri E, Metelitsa LS, Gunaratne P, Kim ES, Shohet JMCancer researchG-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic. Cancer Res. 2013 Jul 01; 73(13):4134-46.Cancer Res2013-05-16T00:00:002013G-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic.Authorship 954931831484667Xu X, Huang W, Heczey A, Liu D, Guo L, Wood M, Jin J, Courtney AN, Liu B, Di Pierro EJ, Hicks J, Barragan GA, Ngai H, Chen Y, Savoldo B, Dotti G, Metelitsa LSClinical cancer research : an official journal of the American Association for Cancer ResearchNKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced In Vivo Persistence and Antitumor Activity against Neuroblastoma. Clin Cancer Res. 2019 12 01; 25(23):7126-7138.Clin Cancer Res2019-09-04T00:00:002019NKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced In Vivo Persistence and Antitumor Activity against Neuroblastoma.true1ProfessorProfessorAuthorship 976005431953246Batra SA, Rathi P, Guo L, Courtney AN, Fleurence J, Balzeau J, Shaik RS, Nguyen TP, Wu MF, Bulsara S, Mamonkin M, Metelitsa LS, Heczey ACancer immunology researchGlypican-3-Specific CAR T Cells Coexpressing IL15 and IL21 Have Superior Expansion and Antitumor Activity against Hepatocellular Carcinoma. Cancer Immunol Res. 2020 03; 8(3):309-320.Cancer Immunol Res2020-01-17T00:00:002020Glypican-3-Specific CAR T Cells Coexpressing IL15 and IL21 Have Superior Expansion and Antitumor Activity against Hepatocellular Carcinoma.Authorship 1002698233046868Heczey A, Courtney AN, Montalbano A, Robinson S, Liu K, Li M, Ghatwai N, Dakhova O, Liu B, Raveh-Sadka T, Chauvin-Fleurence CN, Xu X, Ngai H, Di Pierro EJ, Savoldo B, Dotti G, Metelitsa LSNature medicineAnti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis. Nat Med. 2020 11; 26(11):1686-1690.Nat Med2020-10-12T00:00:002020Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis.Authorship 1024439234220380Starosolski Z, Courtney AN, Srivastava M, Guo L, Stupin I, Metelitsa LS, Annapragada A, Ghaghada KBContrast media & molecular imagingA Nanoradiomics Approach for Differentiation of Tumors Based on Tumor-Associated Macrophage Burden. Contrast Media Mol Imaging. 2021; 2021:6641384.Contrast Media Mol Imaging2021-06-14T00:00:002021A Nanoradiomics Approach for Differentiation of Tumors Based on Tumor-Associated Macrophage Burden.true1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant ProfessorPediatricts-Oncology AICTAuthorship 10611291Authorship 1062395636347021Courtney AN, Tian G, Metelitsa LSBloodNatural killer T cells and other innate-like T?lymphocytes as emerging platforms for allogeneic cancer cell therapy. Blood. 2023 02 23; 141(8):869-876.Blood2023-02-23T00:00:002023Natural killer T cells and other innate-like T?lymphocytes as emerging platforms for allogeneic cancer cell therapy.36484736Ngai H, Barragan GA, Tian G, Balzeau JC, Zhang C, Courtney AN, Guo L, Xu X, Wood MS, Drabek JM, Demberg T, Sands CM, Chauvin-Fleurence CN, Di Pierro EJ, Rosen JM, Metelitsa LSCancer immunology researchLEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells. Cancer Immunol Res. 2023 02 03; 11(2):171-183.Cancer Immunol Res2023-02-03T00:00:002023LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells.Authorship 1065232636882225Tomolonis JA, Xu X, Dholakia KH, Zhang C, Guo L, Courtney AN, Wang S, Balzeau J, Barrag?n GA, Tian G, Di Pierro EJ, Metelitsa LSJournal for immunotherapy of cancerInteraction between tumor cell TNFR2 and monocyte membrane-bound TNF-a triggers tumorigenic inflammation in neuroblastoma. J Immunother Cancer. 2023 03; 11(3).J Immunother Cancer2023-03-01T00:00:002023Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-a triggers tumorigenic inflammation in neuroblastoma.37188782Heczey A, Xu X, Courtney AN, Tian G, Barragan GA, Guo L, Amador CM, Ghatwai N, Rathi P, Wood MS, Li Y, Zhang C, Demberg T, Di Pierro EJ, Sher AC, Zhang H, Mehta B, Thakkar SG, Grilley B, Wang T, Weiss BD, Montalbano A, Subramaniam M, Xu C, Sachar C, Wells DK, Dotti G, Metelitsa LSNature medicineAnti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results. Nat Med. 2023 Jun; 29(6):1379-1388.Nat Med2023-05-15T00:00:002023Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results.true1Adjunct ProfessorAdjunct ProfessorAuthorship 10707883true1InstructorInstructorAuthorship 1086650338195754Heczey A, Xu X, Courtney AN, Tian G, Barragan GA, Guo L, Amador CM, Ghatwai N, Rathi P, Wood MS, Li Y, Zhang C, Demberg T, Di Pierro EJ, Sher AC, Zhang H, Mehta B, Thakkar SG, Grilley B, Wang T, Weiss BD, Montalbano A, Subramaniam M, Xu C, Sachar C, Wells DK, Dotti G, Metelitsa LSNature medicineAuthor Correction: Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results. Nat Med. 2024 Jan 09.Nat Med2024-01-09T00:00:002024Author Correction: Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results.true1ProfessorProfessortrue1Associate ProfessorAssociate Professor1102 BATESHouston, 77030TX2.559260.00628382148research areas2.90770.021883224coauthor of31.57543.5003360similar to1122selected publicationsAuthorship 1536453Authorship 1536472Authorship 1536498Authorship 1542536Authorship 1543381Authorship 1544291Authorship 1545622Authorship 15502813Authorship 1550439Authorship 1559824