Connection

THOMAS LLOYD to Animals

This is a "connection" page, showing publications THOMAS LLOYD has written about Animals.
Connection Strength

0.771
  1. Aberrant nuclear pore complex degradation contributes to neurodegeneration in VCP disease. Neuron. 2026 Mar 04; 114(5):850-867.e8.
    View in: PubMed
    Score: 0.053
  2. Disrupted endoplasmic reticulum-mediated autophagosomal biogenesis in a Drosophila model of C9-ALS-FTD. Autophagy. 2024 01; 20(1):94-113.
    View in: PubMed
    Score: 0.045
  3. Nucleoporins are degraded via upregulation of ESCRT-III/Vps4 complex in Drosophila models of C9-ALS/FTD. Cell Rep. 2022 09 20; 40(12):111379.
    View in: PubMed
    Score: 0.043
  4. Defective axonal transport of endo-lysosomes and dense core vesicles in a Drosophila model of C9-ALS/FTD. Traffic. 2022 09; 23(9):430-441.
    View in: PubMed
    Score: 0.042
  5. Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis. Sci Transl Med. 2022 01 19; 14(628):eabi9196.
    View in: PubMed
    Score: 0.041
  6. TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS. Elife. 2020 12 10; 9.
    View in: PubMed
    Score: 0.038
  7. TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca2. Nat Commun. 2020 05 29; 11(1):2679.
    View in: PubMed
    Score: 0.036
  8. Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice. J Vis Exp. 2019 09 16; (151).
    View in: PubMed
    Score: 0.035
  9. Drosophila models of amyotrophic lateral sclerosis with defects in RNA metabolism. Brain Res. 2018 08 15; 1693(Pt A):109-120.
    View in: PubMed
    Score: 0.031
  10. FUS causes synaptic hyperexcitability in Drosophila dendritic arborization neurons. Brain Res. 2018 08 15; 1693(Pt A):55-66.
    View in: PubMed
    Score: 0.031
  11. Nucleocytoplasmic transport in C9orf72-mediated ALS/FTD. Nucleus. 2016 Apr 25; 7(2):132-7.
    View in: PubMed
    Score: 0.027
  12. FIG4 regulates lysosome membrane homeostasis independent of phosphatase function. Hum Mol Genet. 2016 Feb 15; 25(4):681-92.
    View in: PubMed
    Score: 0.027
  13. Drosophila models of neurologic disease. Exp Neurol. 2015 Dec; 274(Pt A):1-3.
    View in: PubMed
    Score: 0.027
  14. The ALS gene FUS regulates synaptic transmission at the Drosophila neuromuscular junction. Hum Mol Genet. 2014 Jul 15; 23(14):3810-22.
    View in: PubMed
    Score: 0.024
  15. Axonal transport disruption in peripheral nerve disease: From Jack's discoveries as a resident to recent contributions. J Peripher Nerv Syst. 2012 Dec; 17 Suppl 3:46-51.
    View in: PubMed
    Score: 0.022
  16. The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini. Neuron. 2012 Apr 26; 74(2):344-60.
    View in: PubMed
    Score: 0.021
  17. Characterizing local antibody responses in the muscle of inclusion body myositis patients. J Autoimmun. 2025 Jun; 154:103437.
    View in: PubMed
    Score: 0.013
  18. Emerging mechanisms and therapeutics in inflammatory muscle diseases. Trends Pharmacol Sci. 2025 03; 46(3):249-263.
    View in: PubMed
    Score: 0.013
  19. Seeding-competent TDP-43 persists in human patient and mouse muscle. Sci Transl Med. 2024 11 27; 16(775):eadp5730.
    View in: PubMed
    Score: 0.012
  20. Safety and efficacy of arimoclomol for inclusion body myositis: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2023 10; 22(10):900-911.
    View in: PubMed
    Score: 0.011
  21. c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD. J Neurosci. 2023 04 26; 43(17):3186-3197.
    View in: PubMed
    Score: 0.011
  22. When cell biology meets development: endocytic regulation of signaling pathways. Genes Dev. 2002 Jun 01; 16(11):1314-36.
    View in: PubMed
    Score: 0.010
  23. Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy. Nat Commun. 2022 04 28; 13(1):2306.
    View in: PubMed
    Score: 0.010
  24. Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment. Cell Stem Cell. 2022 04 07; 29(4):610-619.e5.
    View in: PubMed
    Score: 0.010
  25. Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell. 2002 Jan 25; 108(2):261-9.
    View in: PubMed
    Score: 0.010
  26. Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. Nat Neurosci. 2021 12; 24(12):1673-1685.
    View in: PubMed
    Score: 0.010
  27. UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction. Cell Rep. 2021 03 30; 34(13):108925.
    View in: PubMed
    Score: 0.010
  28. Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension. Nat Commun. 2021 03 04; 12(1):1444.
    View in: PubMed
    Score: 0.010
  29. p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR). Cell. 2021 02 04; 184(3):689-708.e20.
    View in: PubMed
    Score: 0.009
  30. Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis. Ann Rheum Dis. 2020 09; 79(9):1234-1242.
    View in: PubMed
    Score: 0.009
  31. Variation in SIPA1L2 is correlated with phenotype modification in Charcot- Marie- Tooth disease type 1A. Ann Neurol. 2019 03; 85(3):316-330.
    View in: PubMed
    Score: 0.008
  32. Heterogeneity in gut microbiota drive polyphenol metabolism that influences a-synuclein misfolding and toxicity. J Nutr Biochem. 2019 02; 64:170-181.
    View in: PubMed
    Score: 0.008
  33. TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle. Nature. 2018 11; 563(7732):508-513.
    View in: PubMed
    Score: 0.008
  34. Mutant Huntingtin Disrupts the Nuclear Pore Complex. Neuron. 2017 Apr 05; 94(1):93-107.e6.
    View in: PubMed
    Score: 0.007
  35. Tdp-43 cryptic exons are highly variable between cell types. Mol Neurodegener. 2017 02 02; 12(1):13.
    View in: PubMed
    Score: 0.007
  36. Proteomics of rimmed vacuoles define new risk allele in inclusion body myositis. Ann Neurol. 2017 Feb; 81(2):227-239.
    View in: PubMed
    Score: 0.007
  37. The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature. 2015 Sep 03; 525(7567):56-61.
    View in: PubMed
    Score: 0.007
  38. A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission. Neuron. 2014 Nov 19; 84(4):764-77.
    View in: PubMed
    Score: 0.006
  39. Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathy. Am J Hum Genet. 2014 Sep 04; 95(3):332-9.
    View in: PubMed
    Score: 0.006
  40. WIDE AWAKE mediates the circadian timing of sleep onset. Neuron. 2014 Apr 02; 82(1):151-66.
    View in: PubMed
    Score: 0.006
  41. Cbl-associated protein regulates assembly and function of two tension-sensing structures in Drosophila. Development. 2013 Feb 01; 140(3):627-38.
    View in: PubMed
    Score: 0.005
  42. Endophilin mutations block clathrin-mediated endocytosis but not neurotransmitter release. Cell. 2002 Apr 05; 109(1):101-12.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.