THOMAS LLOYD to Animals
This is a "connection" page, showing publications THOMAS LLOYD has written about Animals.
Connection Strength
0.771
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Aberrant nuclear pore complex degradation contributes to neurodegeneration in VCP disease. Neuron. 2026 Mar 04; 114(5):850-867.e8.
Score: 0.053
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Disrupted endoplasmic reticulum-mediated autophagosomal biogenesis in a Drosophila model of C9-ALS-FTD. Autophagy. 2024 01; 20(1):94-113.
Score: 0.045
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Nucleoporins are degraded via upregulation of ESCRT-III/Vps4 complex in Drosophila models of C9-ALS/FTD. Cell Rep. 2022 09 20; 40(12):111379.
Score: 0.043
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Defective axonal transport of endo-lysosomes and dense core vesicles in a Drosophila model of C9-ALS/FTD. Traffic. 2022 09; 23(9):430-441.
Score: 0.042
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Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis. Sci Transl Med. 2022 01 19; 14(628):eabi9196.
Score: 0.041
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TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS. Elife. 2020 12 10; 9.
Score: 0.038
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TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca2. Nat Commun. 2020 05 29; 11(1):2679.
Score: 0.036
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Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice. J Vis Exp. 2019 09 16; (151).
Score: 0.035
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Drosophila models of amyotrophic lateral sclerosis with defects in RNA metabolism. Brain Res. 2018 08 15; 1693(Pt A):109-120.
Score: 0.031
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FUS causes synaptic hyperexcitability in Drosophila dendritic arborization neurons. Brain Res. 2018 08 15; 1693(Pt A):55-66.
Score: 0.031
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Nucleocytoplasmic transport in C9orf72-mediated ALS/FTD. Nucleus. 2016 Apr 25; 7(2):132-7.
Score: 0.027
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FIG4 regulates lysosome membrane homeostasis independent of phosphatase function. Hum Mol Genet. 2016 Feb 15; 25(4):681-92.
Score: 0.027
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Drosophila models of neurologic disease. Exp Neurol. 2015 Dec; 274(Pt A):1-3.
Score: 0.027
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The ALS gene FUS regulates synaptic transmission at the Drosophila neuromuscular junction. Hum Mol Genet. 2014 Jul 15; 23(14):3810-22.
Score: 0.024
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Axonal transport disruption in peripheral nerve disease: From Jack's discoveries as a resident to recent contributions. J Peripher Nerv Syst. 2012 Dec; 17 Suppl 3:46-51.
Score: 0.022
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The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini. Neuron. 2012 Apr 26; 74(2):344-60.
Score: 0.021
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Characterizing local antibody responses in the muscle of inclusion body myositis patients. J Autoimmun. 2025 Jun; 154:103437.
Score: 0.013
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Emerging mechanisms and therapeutics in inflammatory muscle diseases. Trends Pharmacol Sci. 2025 03; 46(3):249-263.
Score: 0.013
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Seeding-competent TDP-43 persists in human patient and mouse muscle. Sci Transl Med. 2024 11 27; 16(775):eadp5730.
Score: 0.012
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Safety and efficacy of arimoclomol for inclusion body myositis: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2023 10; 22(10):900-911.
Score: 0.011
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c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD. J Neurosci. 2023 04 26; 43(17):3186-3197.
Score: 0.011
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When cell biology meets development: endocytic regulation of signaling pathways. Genes Dev. 2002 Jun 01; 16(11):1314-36.
Score: 0.010
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Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy. Nat Commun. 2022 04 28; 13(1):2306.
Score: 0.010
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Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment. Cell Stem Cell. 2022 04 07; 29(4):610-619.e5.
Score: 0.010
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Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell. 2002 Jan 25; 108(2):261-9.
Score: 0.010
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Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. Nat Neurosci. 2021 12; 24(12):1673-1685.
Score: 0.010
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UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction. Cell Rep. 2021 03 30; 34(13):108925.
Score: 0.010
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Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension. Nat Commun. 2021 03 04; 12(1):1444.
Score: 0.010
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p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR). Cell. 2021 02 04; 184(3):689-708.e20.
Score: 0.009
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Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis. Ann Rheum Dis. 2020 09; 79(9):1234-1242.
Score: 0.009
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Variation in SIPA1L2 is correlated with phenotype modification in Charcot- Marie- Tooth disease type 1A. Ann Neurol. 2019 03; 85(3):316-330.
Score: 0.008
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Heterogeneity in gut microbiota drive polyphenol metabolism that influences a-synuclein misfolding and toxicity. J Nutr Biochem. 2019 02; 64:170-181.
Score: 0.008
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TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle. Nature. 2018 11; 563(7732):508-513.
Score: 0.008
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Mutant Huntingtin Disrupts the Nuclear Pore Complex. Neuron. 2017 Apr 05; 94(1):93-107.e6.
Score: 0.007
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Tdp-43 cryptic exons are highly variable between cell types. Mol Neurodegener. 2017 02 02; 12(1):13.
Score: 0.007
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Proteomics of rimmed vacuoles define new risk allele in inclusion body myositis. Ann Neurol. 2017 Feb; 81(2):227-239.
Score: 0.007
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The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature. 2015 Sep 03; 525(7567):56-61.
Score: 0.007
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A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission. Neuron. 2014 Nov 19; 84(4):764-77.
Score: 0.006
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Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathy. Am J Hum Genet. 2014 Sep 04; 95(3):332-9.
Score: 0.006
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WIDE AWAKE mediates the circadian timing of sleep onset. Neuron. 2014 Apr 02; 82(1):151-66.
Score: 0.006
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Cbl-associated protein regulates assembly and function of two tension-sensing structures in Drosophila. Development. 2013 Feb 01; 140(3):627-38.
Score: 0.005
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Endophilin mutations block clathrin-mediated endocytosis but not neurotransmitter release. Cell. 2002 Apr 05; 109(1):101-12.
Score: 0.003