JonathanLeiJonathan Thomas Lei7618Lei, JonathanThomasPostdoc Fellows and Associatesprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonInvestigational Cancer TherapeuticsLeukemiaMolecular & Cellular OncologySystems BiologyMD AndersonMIEN-CHIEHUNGMIEN-CHIE HUNG8427HUNG, MIEN-CHIEProfessorHAGOP MKANTARJIANHAGOP M KANTARJIAN8501KANTARJIAN, HAGOP MProfessorKELLY KHUNTKELLY K HUNT8555HUNT, KELLY KProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessorFUNDAMERIC-BERNSTAMFUNDA MERIC-BERNSTAM8778MERIC-BERNSTAM, FUNDAProfessorMEENAKSHIANURAGMEENAKSHI ANURAG11102ANURAG, MEENAKSHIAssistant ProfessorAuthorship 315300226977876Haricharan S, Lei J, Ellis MCancer cellMammary Ductal Environment Is Necessary for Faithful Maintenance of Estrogen Signaling in ER? Breast Cancer. Cancer Cell. 2016 Mar 14; 29(3):249-250.Cancer Cell2016-03-14T00:00:002016Mammary Ductal Environment Is Necessary for Faithful Maintenance of Estrogen Signaling in ER? Breast Cancer.Authorship 3159021527251275Mertins P, Mani DR, Ruggles KV, Gillette MA, Clauser KR, Wang P, Wang X, Qiao JW, Cao S, Petralia F, Kawaler E, Mundt F, Krug K, Tu Z, Lei JT, Gatza ML, Wilkerson M, Perou CM, Yellapantula V, Huang KL, Lin C, McLellan MD, Yan P, Davies SR, Townsend RR, Skates SJ, Wang J, Zhang B, Kinsinger CR, Mesri M, Rodriguez H, Ding L, Paulovich AG, Feny? D, Ellis MJ, Carr SA, NCI CPTACNatureProteogenomics connects somatic mutations to signalling in breast cancer. Nature. 2016 06 02; 534(7605):55-62.Nature2016-05-25T00:00:002016Proteogenomics connects somatic mutations to signalling in breast cancer.74Professor10Assistant Professor54InstructorBreast Surgical Oncology53Graduate Student17227823Martinez-Moczygemba M, Huston DP, Lei JTJournal of leukocyte biologyJAK kinases control IL-5 receptor ubiquitination, degradation, and internalization. J Leukoc Biol. 2007 Apr; 81(4):1137-48.J Leukoc Biol2007-01-16T00:00:002007JAK kinases control IL-5 receptor ubiquitination, degradation, and internalization.18955567Martinez-Moczygemba M, Doan ML, Elidemir O, Fan LL, Cheung SW, Lei JT, Moore JP, Tavana G, Lewis LR, Zhu Y, Muzny DM, Gibbs RA, Huston DPThe Journal of experimental medicinePulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1. J Exp Med. 2008 Nov 24; 205(12):2711-6.J Exp Med2008-10-27T00:00:002008Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1.Authorship 876661828801307Haricharan S, Punturi N, Singh P, Holloway KR, Anurag M, Schmelz J, Schmidt C, Lei JT, Suman V, Hunt K, Olson JA, Hoog J, Li S, Huang S, Edwards DP, Kavuri SM, Bainbridge MN, Ma CX, Ellis MJCancer discoveryLoss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer. Cancer Discov. 2017 10; 7(10):1168-1183.Cancer Discov2017-08-11T00:00:002017Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer.29748621Gates LA, Gu G, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, Jung SY, Malovannaya A, Li S, Shao J, Roeder RG, Ellis MJ, Qin J, Fuqua SAW, O'Malley BW, Foulds CEOncogeneProteomic profiling identifies key coactivators utilized by mutant ERa proteins as potential new therapeutic targets. Oncogene. 2018 08; 37(33):4581-4598.Oncogene2018-05-11T00:00:002018Proteomic profiling identifies key coactivators utilized by mutant ERa proteins as potential new therapeutic targets.D004705Physiology1432250.902451EndocytosisD053649Chemicals & Drugs460.992287Receptors, Interleukin-5D001943Disorders1430156220.176287Breast NeoplasmsAuthorship 9296885Authorship 9305171Authorship 932247830089255Lei JT, Shao J, Zhang J, Iglesia M, Chan DW, Cao J, Anurag M, Singh P, He X, Kosaka Y, Matsunuma R, Crowder R, Hoog J, Phommaly C, Goncalves R, Ramalho S, Peres RMR, Punturi N, Schmidt C, Bartram A, Jou E, Devarakonda V, Holloway KR, Lai WV, Hampton O, Rogers A, Tobias E, Parikh PA, Davies SR, Li S, Ma CX, Suman VJ, Hunt KK, Watson MA, Hoadley KA, Thompson EA, Chen X, Kavuri SM, Creighton CJ, Maher CA, Perou CM, Haricharan S, Ellis MJCell reportsFunctional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer. Cell Rep. 2018 08 07; 24(6):1434-1444.e7.Cell Rep2018-08-07T00:00:002018Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer.30498031Matsunuma R, Chan DW, Kim BJ, Singh P, Han A, Saltzman AB, Cheng C, Lei JT, Wang J, Roberto da Silva L, Sahin E, Leng M, Fan C, Perou CM, Malovannaya A, Ellis MJProceedings of the National Academy of Sciences of the United States of AmericaDPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer. Proc Natl Acad Sci U S A. 2018 12 18; 115(51):E11978-E11987.Proc Natl Acad Sci U S A2018-11-29T00:00:002018DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer.D047628Chemicals & Drugs2397010.691832Estrogen Receptor alphaDepartment of MedicineMedicine-General MedicineMedicine-Hematology & OncologyBaylor College of MedicineCHARLESFOULDSCHARLES FOULDS39.09225730000000-77.20961730000000974FOULDS, CHARLESAssistant ProfessorAuthorship 943661130525098Lei JT, Gou X, Ellis MJMolecular & cellular oncologyESR1 fusions drive endocrine therapy resistance and metastasis in breast cancer. Mol Cell Oncol. 2018; 5(6):e1526005.Mol Cell Oncol2018-10-09T00:00:002018ESR1 fusions drive endocrine therapy resistance and metastasis in breast cancer.D00007169653870.918132ProteogenomicsAuthorship 9469784Authorship 947392131099189Rodrigues-Peres RM, de S Carvalho B, Anurag M, Lei JT, Conz L, Gon?alves R, Cardoso Filho C, Ramalho S, de Paiva GR, Derchain SFM, Lopes-Cendes I, Ellis MJ, Sarian LOMolecular genetics & genomic medicineCopy number alterations associated with clinical features in an underrepresented population with breast cancer. Mol Genet Genomic Med. 2019 07; 7(7):e00750.Mol Genet Genomic Med2019-05-16T00:00:002019Copy number alterations associated with clinical features in an underrepresented population with breast cancer.31106278Lei JT, Gou X, Seker S, Ellis MJJournal of cancer metastasis and treatmentESR1 alterations and metastasis in estrogen receptor positive breast cancer. J Cancer Metastasis Treat. 2019; 5.J Cancer Metastasis Treat2019-05-04T00:00:002019ESR1 alterations and metastasis in estrogen receptor positive breast cancer.Quantitative & Computational BiosciencesAuthorship 962633131839155Lei JT, Anurag M, Haricharan S, Gou X, Ellis MJBreast (Edinburgh, Scotland)Endocrine therapy resistance: new insights. Breast. 2019 Nov; 48 Suppl 1:S26-S30.Breast2019-11-01T00:00:002019Endocrine therapy resistance: new insights.true1Assistant ProfessorAssistant Professor71Postdoc Fellows and AssociatesPostDocZEYIZHENGZEYI ZHENG0.000000000000000.000000000000005923ZHENG, ZEYIInstructorANNAMALOVANNAYAANNA MALOVANNAYA0.000000000000000.000000000000005735MALOVANNAYA, ANNAAssistant ProfessorAuthorship 979873332142667Zheng ZY, Anurag M, Lei JT, Cao J, Singh P, Peng J, Kennedy H, Nguyen NC, Chen Y, Lavere P, Li J, Du XH, Cakar B, Song W, Kim BJ, Shi J, Seker S, Chan DW, Zhao GQ, Chen X, Banks KC, Lanman RB, Shafaee MN, Zhang XH, Vasaikar S, Zhang B, Hilsenbeck SG, Li W, Foulds CE, Ellis MJ, Chang ECCancer cellNeurofibromin Is an Estrogen Receptor-a Transcriptional Co-repressor in Breast Cancer. Cancer Cell. 2020 03 16; 37(3):387-402.e7.Cancer Cell2020-03-05T00:00:002020Neurofibromin Is an Estrogen Receptor-a Transcriptional Co-repressor in Breast Cancer.true1Graduate StudentGraduate StudentChang InMoonChang In Moon15808Moon, Chang InGraduate StudentAuthorship 10053111333212010Krug K, Jaehnig EJ, Satpathy S, Blumenberg L, Karpova A, Anurag M, Miles G, Mertins P, Geffen Y, Tang LC, Heiman DI, Cao S, Maruvka YE, Lei JT, Huang C, Kothadia RB, Colaprico A, Birger C, Wang J, Dou Y, Wen B, Shi Z, Liao Y, Wiznerowicz M, Wyczalkowski MA, Chen XS, Kennedy JJ, Paulovich AG, Thiagarajan M, Kinsinger CR, Hiltke T, Boja ES, Mesri M, Robles AI, Rodriguez H, Westbrook TF, Ding L, Getz G, Clauser KR, Feny? D, Ruggles KV, Zhang B, Mani DR, Carr SA, Ellis MJ, Gillette MA, Clinical Proteomic Tumor Analysis ConsortiumCellProteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy. Cell. 2020 11 25; 183(5):1436-1456.e31.Cell2020-11-18T00:00:002020Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.Authorship 1008507933417831Huang C, Chen L, Savage SR, Eguez RV, Dou Y, Li Y, da Veiga Leprevost F, Jaehnig EJ, Lei JT, Wen B, Schnaubelt M, Krug K, Song X, Cieslik M, Chang HY, Wyczalkowski MA, Li K, Colaprico A, Li QK, Clark DJ, Hu Y, Cao L, Pan J, Wang Y, Cho KC, Shi Z, Liao Y, Jiang W, Anurag M, Ji J, Yoo S, Zhou DC, Liang WW, Wendl M, Vats P, Carr SA, Mani DR, Zhang Z, Qian J, Chen XS, Pico AR, Wang P, Chinnaiyan AM, Ketchum KA, Kinsinger CR, Robles AI, An E, Hiltke T, Mesri M, Thiagarajan M, Weaver AM, Sikora AG, Lubinski J, Wierzbicka M, Wiznerowicz M, Satpathy S, Gillette MA, Miles G, Ellis MJ, Omenn GS, Rodriguez H, Boja ES, Dhanasekaran SM, Ding L, Nesvizhskii AI, El-Naggar AK, Chan DW, Zhang H, Zhang B, Clinical Proteomic Tumor Analysis ConsortiumCancer cellProteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma. Cancer Cell. 2021 03 08; 39(3):361-379.e16.Cancer Cell2021-01-07T00:00:002021Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma.true1InstructorInstructorAuthorship 1014569133767418Lei JT, Zhang BBritish journal of cancerProteogenomics drives therapeutic hypothesis generation for precision oncology. Br J Cancer. 2021 07; 125(1):1-3.Br J Cancer2021-03-25T00:00:002021Proteogenomics drives therapeutic hypothesis generation for precision oncology.Authorship 10268871334358469Satpathy S, Krug K, Jean Beltran PM, Savage SR, Petralia F, Kumar-Sinha C, Dou Y, Reva B, Kane MH, Avanessian SC, Vasaikar SV, Krek A, Lei JT, Jaehnig EJ, Omelchenko T, Geffen Y, Bergstrom EJ, Stathias V, Christianson KE, Heiman DI, Cieslik MP, Cao S, Song X, Ji J, Liu W, Li K, Wen B, Li Y, G?m?s ZH, Selvan ME, Soundararajan R, Visal TH, Raso MG, Parra ER, Babur ?, Vats P, Anand S, Schraink T, Cornwell M, Rodrigues FM, Zhu H, Mo CK, Zhang Y, da Veiga Leprevost F, Huang C, Chinnaiyan AM, Wyczalkowski MA, Omenn GS, Newton CJ, Schurer S, Ruggles KV, Feny? D, Jewell SD, Thiagarajan M, Mesri M, Rodriguez H, Mani SA, Udeshi ND, Getz G, Suh J, Li QK, Hostetter G, Paik PK, Dhanasekaran SM, Govindan R, Ding L, Robles AI, Clauser KR, Nesvizhskii AI, Wang P, Carr SA, Zhang B, Mani DR, Gillette MA, Clinical Proteomic Tumor Analysis ConsortiumCellA proteogenomic portrait of lung squamous cell carcinoma. Cell. 2021 08 05; 184(16):4348-4371.e40.Cell2021-08-05T00:00:002021A proteogenomic portrait of lung squamous cell carcinoma.true1Assistant ProfessorAssistant ProfessorAuthorship 1032665334711608Gou X, Anurag M, Lei JT, Kim BJ, Singh P, Seker S, Fandino D, Han A, Rehman S, Hu J, Korchina V, Doddapaneni H, Dobrolecki LE, Mitsiades N, Lewis MT, Welm AL, Li S, Lee AV, Robinson DR, Foulds CE, Ellis MJCancer researchTranscriptional Reprogramming Differentiates Active from Inactive ESR1 Fusions in Endocrine Therapy-Refractory Metastatic Breast Cancer. Cancer Res. 2021 12 15; 81(24):6259-6272.Cancer Res2021-10-28T00:00:002021Transcriptional Reprogramming Differentiates Active from Inactive ESR1 Fusions in Endocrine Therapy-Refractory Metastatic Breast Cancer.Authorship 1043876735418131Eteleeb AM, Thunuguntla PK, Gelev KZ, Tang CY, Rozycki EB, Miller A, Lei JT, Jayasinghe RG, Dang HX, White NM, Reis-Filho JS, Mardis ER, Ellis MJ, Ding L, Silva-Fisher JM, Maher CANPJ breast cancerLINC00355 regulates p27KIP expression by binding to MENIN to induce proliferation in late-stage relapse breast cancer. NPJ Breast Cancer. 2022 Apr 13; 8(1):49.NPJ Breast Cancer2022-04-13T00:00:002022LINC00355 regulates p27KIP expression by binding to MENIN to induce proliferation in late-stage relapse breast cancer.true1Postdoc Fellows and AssociatesPostdoc Fellows and Associates36258226Zheng ZY, Elsarraj H, Lei JT, Hong Y, Anurag M, Feng L, Kennedy H, Shen Y, Lo F, Zhao Z, Zhang B, Zhang XH, Tawfik OW, Behbod F, Chang ECBreast cancer research : BCRElevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness. Breast Cancer Res. 2022 10 18; 24(1):68.Breast Cancer Res2022-10-18T00:00:002022Elevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness.36105216Goldblatt DL, Valverde Ha G, Wali S, Kulkarni VV, Longmire MK, Jaramillo AM, Chittuluru RP, Fouts A, Martinez-Moczygemba M, Lei JT, Huston DP, Tuvim MJ, Dickey BF, Evans SEFrontiers in pharmacologyEpithelial immunomodulation by aerosolized Toll-like receptor agonists prevents allergic inflammation in airway mucosa in mice. Front Pharmacol. 2022; 13:833380.Front Pharmacol2022-08-29T00:00:002022Epithelial immunomodulation by aerosolized Toll-like receptor agonists prevents allergic inflammation in airway mucosa in mice.36619972Petrosyan V, Dobrolecki LE, Thistlethwaite L, Lewis AN, Sallas C, Srinivasan RR, Lei JT, Kovacevic V, Obradovic P, Ellis MJ, Osborne CK, Rimawi MF, Pavlick A, Shafaee MN, Dowst H, Jain A, Saltzman AB, Malovannaya A, Marangoni E, Welm AL, Welm BE, Li S, Wulf GM, Sonzogni O, Huang C, Vasaikar S, Hilsenbeck SG, Zhang B, Milosavljevic A, Lewis MTiScienceIdentifying biomarkers of differential chemotherapy response in TNBC patient-derived xenografts with a CTD/WGCNA approach. iScience. 2023 Jan 20; 26(1):105799.iScience2022-12-12T00:00:002022Identifying biomarkers of differential chemotherapy response in TNBC patient-derived xenografts with a CTD/WGCNA approach.36001024Anurag M, Jaehnig EJ, Krug K, Lei JT, Bergstrom EJ, Kim BJ, Vashist TD, Huynh AMT, Dou Y, Gou X, Huang C, Shi Z, Wen B, Korchina V, Gibbs RA, Muzny DM, Doddapaneni H, Dobrolecki LE, Rodriguez H, Robles AI, Hiltke T, Lewis MT, Nangia JR, Nemati Shafaee M, Li S, Hagemann IS, Hoog J, Lim B, Osborne CK, Mani DR, Gillette MA, Zhang B, Echeverria GV, Miles G, Rimawi MF, Carr SA, Ademuyiwa FO, Satpathy S, Ellis MJCancer discoveryProteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer. Cancer Discov. 2022 11 02; 12(11):2586-2605.Cancer Discov2022-11-02T00:00:002022Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer.Authorship 10628403Authorship 10628894Authorship 106287410Authorship 10628607Authorship 1063219636711982Yi X, Wen B, Ji S, Saltzman A, Jaehnig EJ, Lei JT, Gao Q, Zhang BbioRxiv : the preprint server for biologyDeep learning prediction boosts phosphoproteomics-based discoveries through improved phosphopeptide identification. bioRxiv. 2023 Jan 12.bioRxiv2023-01-12T00:00:002023Deep learning prediction boosts phosphoproteomics-based discoveries through improved phosphopeptide identification.Authorship 1068443437071495Gou X, Kim BJ, Anurag M, Lei JT, Young MN, Holt MV, Fandino D, Vollert CT, Singh P, Alzubi MA, Malovannaya A, Dobrolecki LE, Lewis MT, Li S, Foulds CE, Ellis MJCancer researchKinome Reprogramming Is a Targetable Vulnerability in ESR1 Fusion-Driven Breast Cancer. Cancer Res. 2023 10 02; 83(19):3237-3251.Cancer Res2023-10-02T00:00:002023Kinome Reprogramming Is a Targetable Vulnerability in ESR1 Fusion-Driven Breast Cancer.Authorship 1070877137137501Lei JT, Jaehnig EJ, Smith H, Holt MV, Li X, Anurag M, Ellis MJ, Mills GB, Zhang B, Labrie MCold Spring Harbor perspectives in medicineThe Breast Cancer Proteome and Precision Oncology. Cold Spring Harb Perspect Med. 2023 10 03; 13(10).Cold Spring Harb Perspect Med2023-10-03T00:00:002023The Breast Cancer Proteome and Precision Oncology.Authorship 10732271037390209Oropeza E, Seker S, Carrel S, Mazumder A, Lozano D, Jimenez A, VandenHeuvel SN, Noltensmeyer DA, Punturi NB, Lei JT, Lim B, Waltz SE, Raghavan SA, Bainbridge MN, Haricharan SScience advancesMolecular portraits of cell cycle checkpoint kinases in cancer evolution, progression, and treatment responsiveness. Sci Adv. 2023 06 30; 9(26):eadf2860.Sci Adv2023-06-30T00:00:002023Molecular portraits of cell cycle checkpoint kinases in cancer evolution, progression, and treatment responsiveness.Authorship 1075654337501682Kim BJ, Zheng ZY, Lei JT, Holt MV, Chen A, Peng J, Fandino D, Singh P, Kennedy H, Dou Y, Chica-Parrado MDR, Bikorimana E, Ye D, Wang Y, Hanker AB, Mohamed N, Hilsenbeck SG, Lim B, Asirvatham JR, Sreekumar A, Zhang B, Miles G, Anurag M, Ellis MJ, Chang ECCancer research communicationsProteogenomic Approaches for the Identification of NF1/Neurofibromin-depleted Estrogen Receptor-positive Breast Cancers for Targeted Treatment. Cancer Res Commun. 2023 07; 3(7):1366-1377.Cancer Res Commun2023-07-26T00:00:002023Proteogenomic Approaches for the Identification of NF1/Neurofibromin-depleted Estrogen Receptor-positive Breast Cancers for Targeted Treatment.true1Assistant ProfessorAssistant ProfessorDepartment of Biochemistry and Molecular PharmacologyBiochemistry & Mol Pharmacology37567170Dou Y, Katsnelson L, Gritsenko MA, Hu Y, Reva B, Hong R, Wang YT, Kolodziejczak I, Lu RJ, Tsai CF, Bu W, Liu W, Guo X, An E, Arend RC, Bavarva J, Chen L, Chu RK, Czekanski A, Davoli T, Demicco EG, DeLair D, Devereaux K, Dhanasekaran SM, Dottino P, Dover B, Fillmore TL, Foxall M, Hermann CE, Hiltke T, Hostetter G, Jedryka M, Jewell SD, Johnson I, Kahn AG, Ku AT, Kumar-Sinha C, Kurzawa P, Lazar AJ, Lazcano R, Lei JT, Li Y, Liao Y, Lih TM, Lin TT, Martignetti JA, Masand RP, Matkowski R, McKerrow W, Mesri M, Monroe ME, Moon J, Moore RJ, Nestor MD, Newton C, Omelchenko T, Omenn GS, Payne SH, Petyuk VA, Robles AI, Rodriguez H, Ruggles KV, Rykunov D, Savage SR, Schepmoes AA, Shi T, Shi Z, Tan J, Taylor M, Thiagarajan M, Wang JM, Weitz KK, Wen B, Williams CM, Wu Y, Wyczalkowski MA, Yi X, Zhang X, Zhao R, Mutch D, Chinnaiyan AM, Smith RD, Nesvizhskii AI, Wang P, Wiznerowicz M, Ding L, Mani DR, Zhang H, Anderson ML, Rodland KD, Zhang B, Liu T, Feny? D, Clinical Proteomic Tumor Analysis ConsortiumCancer cellProteogenomic insights suggest druggable pathways in endometrial carcinoma. Cancer Cell. 2023 09 11; 41(9):1586-1605.e15.Cancer Cell2023-08-10T00:00:002023Proteogenomic insights suggest druggable pathways in endometrial carcinoma.37587913Wang J, Saltzman AB, Jaehnig EJ, Lei JT, Malovannaya A, Holt MV, Young MN, Rimawi MF, Ademuyiwa FO, Anurag M, Kim BJ, Ellis MJCancer research communicationsKinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins. Cancer Res Commun. 2023 08; 3(8):1551-1563.Cancer Res Commun2023-08-15T00:00:002023Kinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins.Authorship 107960134Authorship 10796387Authorship 10796314Authorship 10796284137582339Li Y, Dou Y, Da Veiga Leprevost F, Geffen Y, Calinawan AP, Aguet F, Akiyama Y, Anand S, Birger C, Cao S, Chaudhary R, Chilappagari P, Cieslik M, Colaprico A, Zhou DC, Day C, Domagalski MJ, Esai Selvan M, Feny? D, Foltz SM, Francis A, Gonzalez-Robles T, G?m?s ZH, Heiman D, Holck M, Hong R, Hu Y, Jaehnig EJ, Ji J, Jiang W, Katsnelson L, Ketchum KA, Klein RJ, Lei JT, Liang WW, Liao Y, Lindgren CM, Ma W, Ma L, MacCoss MJ, Martins Rodrigues F, McKerrow W, Nguyen N, Oldroyd R, Pilozzi A, Pugliese P, Reva B, Rudnick P, Ruggles KV, Rykunov D, Savage SR, Schnaubelt M, Schraink T, Shi Z, Singhal D, Song X, Storrs E, Terekhanova NV, Thangudu RR, Thiagarajan M, Wang LB, Wang JM, Wang Y, Wen B, Wu Y, Wyczalkowski MA, Xin Y, Yao L, Yi X, Zhang H, Zhang Q, Zuhl M, Getz G, Ding L, Nesvizhskii AI, Wang P, Robles AI, Zhang B, Payne SH, Clinical Proteomic Tumor Analysis ConsortiumCancer cellProteogenomic data and resources for pan-cancer analysis. Cancer Cell. 2023 08 14; 41(8):1397-1406.Cancer Cell2023-08-14T00:00:002023Proteogenomic data and resources for pan-cancer analysis.37619559Liao Y, Savage SR, Dou Y, Shi Z, Yi X, Jiang W, Lei JT, Zhang BCell systemsA proteogenomics data-driven knowledge base of human cancer. Cell Syst. 2023 09 20; 14(9):777-787.e5.Cell Syst2023-08-23T00:00:002023A proteogenomics data-driven knowledge base of human cancer.Authorship 1080967337811874Moon CI, Elizarraras JM, Lei JT, Jia B, Zhang BNucleic acids researchClinicalOmicsDB: exploring molecular associations of oncology drug responses in clinical trials. Nucleic Acids Res. 2024 Jan 05; 52(D1):D1201-D1209.Nucleic Acids Res2024-01-05T00:00:002024ClinicalOmicsDB: exploring molecular associations of oncology drug responses in clinical trials.Authorship 1085816638154692Yi X, Wen B, Ji S, Saltzman AB, Jaehnig EJ, Lei JT, Gao Q, Zhang BMolecular & cellular proteomics : MCPDeep Learning Prediction Boosts Phosphoproteomics-Based Discoveries Through Improved Phosphopeptide Identification. Mol Cell Proteomics. 2024 Feb; 23(2):100707.Mol Cell Proteomics2023-12-26T00:00:002023Deep Learning Prediction Boosts Phosphoproteomics-Based Discoveries Through Improved Phosphopeptide Identification.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor2.291830.00658154193research areas1.342560.021475941coauthor of26.32086.0234460similar to1136selected publicationsAuthorship 1473551Authorship 1473566Authorship 1473571Authorship 147358321965659Lei JT, Mazumdar T, Martinez-Moczygemba MThe Journal of biological chemistryThree lysine residues in the common ? chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signaling. J Biol Chem. 2011 Nov 18; 286(46):40091-103.J Biol Chem2011-09-30T00:00:002011Three lysine residues in the common ? chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signaling.18511572Lei JT, Martinez-Moczygemba MJournal of leukocyte biologySeparate endocytic pathways regulate IL-5 receptor internalization and signaling. J Leukoc Biol. 2008 Aug; 84(2):499-509.J Leukoc Biol2008-05-29T00:00:002008Separate endocytic pathways regulate IL-5 receptor internalization and signaling.