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MICHAEL TAYLOR to Humans

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This is a "connection" page, showing publications MICHAEL TAYLOR has written about Humans.
MICHAEL TAYLOR
Connection Strength
1.959
Humans
  1. ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip. Nat Genet. 2025 Jan; 57(1):88-102.
    View in: PubMed
    Score: 0.025
  2. Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma. Cell. 2024 Aug 22; 187(17):4733-4750.e26.
    View in: PubMed
    Score: 0.024
  3. Amplifying natural antitumor immunity for personalized immunotherapy. Cell Res. 2022 06; 32(6):505-506.
    View in: PubMed
    Score: 0.020
  4. Nailing a Fe-rocious form of cancer. Science. 2020 07 17; 369(6501):250-251.
    View in: PubMed
    Score: 0.018
  5. Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma. Nat Med. 2020 05; 26(5):720-731.
    View in: PubMed
    Score: 0.018
  6. The molecular biology of medulloblastoma metastasis. Brain Pathol. 2020 05; 30(3):691-702.
    View in: PubMed
    Score: 0.017
  7. Postoperative isolated lower extremity supplementary motor area syndrome: case report and review of the literature. Childs Nerv Syst. 2020 01; 36(1):189-195.
    View in: PubMed
    Score: 0.017
  8. Medulloblastoma in the age of molecular subgroups: a review. J Neurosurg Pediatr. 2019 10 01; 24(4):353-363.
    View in: PubMed
    Score: 0.017
  9. Childhood cerebellar tumours mirror conserved fetal transcriptional programs. Nature. 2019 08; 572(7767):67-73.
    View in: PubMed
    Score: 0.017
  10. Bioinformatic Strategies for the Genomic and Epigenomic Characterization of Brain Tumors. Methods Mol Biol. 2019; 1869:37-56.
    View in: PubMed
    Score: 0.016
  11. CAR T cells for childhood diffuse midline gliomas. Nat Med. 2018 05; 24(5):534-535.
    View in: PubMed
    Score: 0.015
  12. A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell. 2018 02 22; 172(5):1050-1062.e14.
    View in: PubMed
    Score: 0.015
  13. Review of molecular classification and treatment implications of pediatric brain tumors. Curr Opin Pediatr. 2018 02; 30(1):3-9.
    View in: PubMed
    Score: 0.015
  14. Pontine Infantile Glioma Simplified. Cancer Cell. 2017 11 13; 32(5):548-549.
    View in: PubMed
    Score: 0.015
  15. Put away your microscopes: the ependymoma molecular era has begun. Curr Opin Oncol. 2017 Nov; 29(6):443-447.
    View in: PubMed
    Score: 0.015
  16. Cancer: Drain the swamp to beat glioma. Nature. 2017 09 28; 549(7673):460-461.
    View in: PubMed
    Score: 0.015
  17. The role of angiogenesis in Group 3 medulloblastoma pathogenesis and survival. Neuro Oncol. 2017 Sep 01; 19(9):1217-1227.
    View in: PubMed
    Score: 0.015
  18. Transposase-driven rearrangements in human tumors. Nat Genet. 2017 Jun 28; 49(7):975-977.
    View in: PubMed
    Score: 0.015
  19. Medulloblastoma: From Myth to Molecular. J Clin Oncol. 2017 Jul 20; 35(21):2355-2363.
    View in: PubMed
    Score: 0.015
  20. Tailoring Medulloblastoma Treatment Through Genomics: Making a Change, One Subgroup at a Time. Annu Rev Genomics Hum Genet. 2017 08 31; 18:143-166.
    View in: PubMed
    Score: 0.014
  21. Treatment implications of posterior fossa ependymoma subgroups. Chin J Cancer. 2016 11 15; 35(1):93.
    View in: PubMed
    Score: 0.014
  22. Fall of the Optical Wall: Freedom from the Tyranny of the Microscope Improves Glioma Risk Stratification. Cancer Cell. 2016 Feb 08; 29(2):137-8.
    View in: PubMed
    Score: 0.013
  23. p53 and Meduloblastoma. Cold Spring Harb Perspect Med. 2015 Dec 18; 6(2):a026278.
    View in: PubMed
    Score: 0.013
  24. The Amazing and Deadly Glioma Race. Cancer Cell. 2015 Sep 14; 28(3):275-7.
    View in: PubMed
    Score: 0.013
  25. Genetic and molecular alterations across medulloblastoma subgroups. J Mol Med (Berl). 2015 Oct; 93(10):1075-84.
    View in: PubMed
    Score: 0.013
  26. Posterior fossa ependymoma: current insights. Childs Nerv Syst. 2015 Oct; 31(10):1699-706.
    View in: PubMed
    Score: 0.013
  27. Pediatric cancer genomics, a play rather than a portrait. Nat Genet. 2015 Aug; 47(8):851-2.
    View in: PubMed
    Score: 0.013
  28. Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype. Clin Cancer Res. 2015 Aug 15; 21(16):3750-8.
    View in: PubMed
    Score: 0.013
  29. Neoadjuvant chemotherapy reduces blood loss during the resection of pediatric choroid plexus carcinomas. J Neurosurg Pediatr. 2015 Aug; 16(2):126-33.
    View in: PubMed
    Score: 0.013
  30. [Molecular subgrouping and characterization analysis of medulloblastomas in a cohort of Japanese patients]. No Shinkei Geka. 2015 Feb; 43(2):117-25.
    View in: PubMed
    Score: 0.012
  31. Clinical implications of medulloblastoma subgroups: incidence of CSF diversion surgery. J Neurosurg Pediatr. 2015 Mar; 15(3):236-42.
    View in: PubMed
    Score: 0.012
  32. An epigenetic therapy for diffuse intrinsic pontine gliomas. Nat Med. 2014 Dec; 20(12):1378-9.
    View in: PubMed
    Score: 0.012
  33. Medulloblastoma molecular dissection: the way toward targeted therapy. Curr Opin Oncol. 2013 Nov; 25(6):674-81.
    View in: PubMed
    Score: 0.011
  34. Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis. Lancet Oncol. 2013 Nov; 14(12):1200-7.
    View in: PubMed
    Score: 0.011
  35. Intertumoral and intratumoral heterogeneity as a barrier for effective treatment of medulloblastoma. Neurosurgery. 2013 Aug; 60 Suppl 1:57-63.
    View in: PubMed
    Score: 0.011
  36. Emerging insights into the ependymoma epigenome. Brain Pathol. 2013 Mar; 23(2):206-9.
    View in: PubMed
    Score: 0.011
  37. Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. Acta Neuropathol. 2013 Mar; 125(3):373-84.
    View in: PubMed
    Score: 0.011
  38. Molecular subgroups of medulloblastoma. Expert Rev Neurother. 2012 Jul; 12(7):871-84.
    View in: PubMed
    Score: 0.010
  39. The clinical implications of medulloblastoma subgroups. Nat Rev Neurol. 2012 May 08; 8(6):340-51.
    View in: PubMed
    Score: 0.010
  40. Subgroup-specific alternative splicing in medulloblastoma. Acta Neuropathol. 2012 Apr; 123(4):485-499.
    View in: PubMed
    Score: 0.010
  41. Clonal selection drives genetic divergence of metastatic medulloblastoma. Nature. 2012 Feb 15; 482(7386):529-33.
    View in: PubMed
    Score: 0.010
  42. The epigenetics of brain tumors. Methods Mol Biol. 2012; 863:139-53.
    View in: PubMed
    Score: 0.010
  43. Genome-wide methylation analysis. Methods Mol Biol. 2012; 863:303-17.
    View in: PubMed
    Score: 0.010
  44. Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol. 2012 Apr; 123(4):465-72.
    View in: PubMed
    Score: 0.010
  45. Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples. Acta Neuropathol. 2012 Apr; 123(4):615-26.
    View in: PubMed
    Score: 0.010
  46. FISH and chips: the recipe for improved prognostication and outcomes for children with medulloblastoma. Cancer Genet. 2011 Nov; 204(11):577-88.
    View in: PubMed
    Score: 0.010
  47. Molecular genetics of ependymoma. Chin J Cancer. 2011 Oct; 30(10):669-81.
    View in: PubMed
    Score: 0.010
  48. Intracerebral malignant peripheral nerve sheath tumor in a child with neurofibromatosis Type 1 and middle cerebral artery aneurysm treated with endovascular coil embolization. J Neurosurg Pediatr. 2011 Oct; 8(4):346-52.
    View in: PubMed
    Score: 0.010
  49. Mouse models of medulloblastoma. Chin J Cancer. 2011 Jul; 30(7):442-9.
    View in: PubMed
    Score: 0.010
  50. Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct. Acta Neuropathol. 2011 Aug; 122(2):231-40.
    View in: PubMed
    Score: 0.010
  51. PCDH10 is a candidate tumour suppressor gene in medulloblastoma. Childs Nerv Syst. 2011 Aug; 27(8):1243-9.
    View in: PubMed
    Score: 0.010
  52. Calculating a cure for cancer: managing medulloblastoma MATH1-ematically. Expert Rev Neurother. 2010 Oct; 10(10):1489-92.
    View in: PubMed
    Score: 0.009
  53. Molecular diagnostics of CNS embryonal tumors. Acta Neuropathol. 2010 Nov; 120(5):553-66.
    View in: PubMed
    Score: 0.009
  54. Medulloblastoma comprises four distinct molecular variants. J Clin Oncol. 2011 Apr 10; 29(11):1408-14.
    View in: PubMed
    Score: 0.009
  55. The genetics of pediatric brain tumors. Curr Neurol Neurosci Rep. 2010 May; 10(3):215-23.
    View in: PubMed
    Score: 0.009
  56. Genomics of medulloblastoma: from Giemsa-banding to next-generation sequencing in 20 years. Neurosurg Focus. 2010 Jan; 28(1):E6.
    View in: PubMed
    Score: 0.009
  57. Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma. Neoplasia. 2010 Jan; 12(1):20-7.
    View in: PubMed
    Score: 0.009
  58. The genetic and epigenetic basis of ependymoma. Childs Nerv Syst. 2009 Oct; 25(10):1195-201.
    View in: PubMed
    Score: 0.008
  59. The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors. Cancer Res. 2009 Apr 15; 69(8):3249-55.
    View in: PubMed
    Score: 0.008
  60. Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. Nat Genet. 2009 Apr; 41(4):465-72.
    View in: PubMed
    Score: 0.008
  61. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell. 2005 Oct; 8(4):323-35.
    View in: PubMed
    Score: 0.006
  62. Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy. Cancer Res. 2025 Oct 01; 85(19):3737-3751.
    View in: PubMed
    Score: 0.006
  63. Co-occurrence of congenital anomalies and childhood brain tumors in 22 million live births. Neuro Oncol. 2025 Sep 08; 27(7):1910-1922.
    View in: PubMed
    Score: 0.006
  64. Unveiling spatial heterogeneity in medulloblastoma: A multi-omics analysis of cellular state and geographical organization. Neuro Oncol. 2025 Jul 30; 27(6):1611-1627.
    View in: PubMed
    Score: 0.006
  65. Therapeutic radiation drives leptomeningeal dissemination of medulloblastoma through an innate immune process. Dev Cell. 2025 Nov 03; 60(21):2880-2896.e7.
    View in: PubMed
    Score: 0.006
  66. Gene context drift identifies drug targets to mitigate cancer treatment resistance. Cancer Cell. 2025 Sep 08; 43(9):1608-1621.e9.
    View in: PubMed
    Score: 0.006
  67. Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth. Nat Cell Biol. 2025 May; 27(5):863-874.
    View in: PubMed
    Score: 0.006
  68. Mapping the developmental profile of ventricular zone-derived neurons in the human cerebellum. Proc Natl Acad Sci U S A. 2025 Apr 29; 122(17):e2415425122.
    View in: PubMed
    Score: 0.006
  69. Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression. Nat Commun. 2025 Mar 26; 16(1):2974.
    View in: PubMed
    Score: 0.006
  70. The T cell receptor landscape of childhood brain tumors. Sci Transl Med. 2025 Mar 19; 17(790):eadp0675.
    View in: PubMed
    Score: 0.006
  71. A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance. Dev Cell. 2025 Jun 09; 60(11):1532-1549.e7.
    View in: PubMed
    Score: 0.006
  72. FOXR2 Targets LHX6+/DLX+ Neural Lineages to Drive Central Nervous System Neuroblastoma. Cancer Res. 2025 Jan 15; 85(2):231-250.
    View in: PubMed
    Score: 0.006
  73. High cellular plasticity state of medulloblastoma local recurrence and distant dissemination. Cell Rep Med. 2025 Jan 21; 6(1):101914.
    View in: PubMed
    Score: 0.006
  74. Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma Neurospheres. Cells. 2025 01 07; 14(2).
    View in: PubMed
    Score: 0.006
  75. Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor binding. Cancer Cell. 2025 Jan 13; 43(1):122-143.e8.
    View in: PubMed
    Score: 0.006
  76. 3D genome topology distinguishes molecular subgroups of medulloblastoma. Am J Hum Genet. 2024 Dec 05; 111(12):2720-2734.
    View in: PubMed
    Score: 0.006
  77. Leptomeningeal metastases from solid tumors: A Society for Neuro-Oncology and American Society of Clinical Oncology consensus review on clinical management and future directions. Neuro Oncol. 2024 Oct 03; 26(10):1781-1804.
    View in: PubMed
    Score: 0.006
  78. A peptide encoded by upstream open reading frame of MYC binds to tropomyosin receptor kinase B and promotes glioblastoma growth in mice. Sci Transl Med. 2024 10 02; 16(767):eadk9524.
    View in: PubMed
    Score: 0.006
  79. Systematic transcriptomic analysis of childhood medulloblastoma identifies N6-methyladenosine-dependent lncRNA signatures associated with molecular subtype, immune cell infiltration, and prognosis. Acta Neuropathol Commun. 2024 08 28; 12(1):138.
    View in: PubMed
    Score: 0.006
  80. The medical and functional burden of surviving childhood ependymoma: A population-based study in Ontario, Canada. Pediatr Blood Cancer. 2024 Nov; 71(11):e31275.
    View in: PubMed
    Score: 0.006
  81. Protocol for the derivation of primary cancer stem cell lines from human ependymal tumors. STAR Protoc. 2024 09 20; 5(3):103260.
    View in: PubMed
    Score: 0.006
  82. A group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing. Nat Cell Biol. 2024 08; 26(8):1233-1246.
    View in: PubMed
    Score: 0.006
  83. TULIPs decorate the three-dimensional genome of PFA ependymoma. Cell. 2024 Sep 05; 187(18):4926-4945.e22.
    View in: PubMed
    Score: 0.006
  84. Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signaling. Oncogene. 2004 Jun 03; 23(26):4577-83.
    View in: PubMed
    Score: 0.006
  85. Protocol for preclinical evaluation of locoregionally delivered CAR T?cells in patient-derived xenograft models of brain tumors. STAR Protoc. 2024 06 21; 5(2):103078.
    View in: PubMed
    Score: 0.006
  86. Postoperative cerebellar mutism syndrome is an acquired autism-like network disturbance. Neuro Oncol. 2024 05 03; 26(5):950-964.
    View in: PubMed
    Score: 0.006
  87. The Virtual Child. Cancer Discov. 2024 Apr 04; 14(4):663-668.
    View in: PubMed
    Score: 0.006
  88. Childhood cancer mutagenesis caused by transposase-derived PGBD5. Sci Adv. 2024 03 22; 10(12):eadn4649.
    View in: PubMed
    Score: 0.006
  89. A therapeutically targetable positive feedback loop between lnc-HLX-2-7, HLX, and MYC that promotes group 3 medulloblastoma. Cell Rep. 2024 03 26; 43(3):113938.
    View in: PubMed
    Score: 0.006
  90. Complications following resection of primary and recurrent pediatric posterior fossa ependymoma. J Neurosurg Pediatr. 2024 04 01; 33(4):367-373.
    View in: PubMed
    Score: 0.006
  91. Developmental basis of SHH medulloblastoma heterogeneity. Nat Commun. 2024 01 08; 15(1):270.
    View in: PubMed
    Score: 0.006
  92. Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism. Nat Cancer. 2024 Jan; 5(1):147-166.
    View in: PubMed
    Score: 0.006
  93. miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4. Acta Neuropathol Commun. 2023 12 19; 11(1):203.
    View in: PubMed
    Score: 0.006
  94. Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome. Neuro Oncol. 2023 12 08; 25(12):2273-2286.
    View in: PubMed
    Score: 0.006
  95. Advanced cancer genetics in neurosurgical research. Neurosurgery. 2003 Nov; 53(5):1168-78; discussion 1178.
    View in: PubMed
    Score: 0.006
  96. The LIN28B-let-7-PBK pathway is essential for group 3 medulloblastoma tumor growth and survival. Mol Oncol. 2023 09; 17(9):1784-1802.
    View in: PubMed
    Score: 0.006
  97. Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer. Nat Commun. 2023 07 18; 14(1):4313.
    View in: PubMed
    Score: 0.006
  98. 3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nat Commun. 2023 04 21; 14(1):2300.
    View in: PubMed
    Score: 0.005
  99. Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma. Cancer Discov. 2023 04 03; 13(4):974-1001.
    View in: PubMed
    Score: 0.005
  100. Bioinformatics in neurosurgery. Neurosurgery. 2003 Apr; 52(4):723-30; discussion 730-1.
    View in: PubMed
    Score: 0.005
  101. A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis. Nat Cell Biol. 2023 03; 25(3):493-507.
    View in: PubMed
    Score: 0.005
  102. Outcomes following management of relapsed pediatric posterior fossa ependymoma in the molecular?era. J Neurooncol. 2023 Feb; 161(3):573-582.
    View in: PubMed
    Score: 0.005
  103. The Burden of Surviving Childhood Medulloblastoma: A Population-Based, Matched Cohort Study in Ontario, Canada. J Clin Oncol. 2023 05 01; 41(13):2372-2381.
    View in: PubMed
    Score: 0.005
  104. Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma. Cancer Res. 2022 12 16; 82(24):4586-4603.
    View in: PubMed
    Score: 0.005
  105. Detection and genomic analysis of BRAF fusions in Juvenile Pilocytic Astrocytoma through the combination and integration of multi-omic data. BMC Cancer. 2022 Dec 12; 22(1):1297.
    View in: PubMed
    Score: 0.005
  106. Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis. Nature. 2022 12; 612(7941):787-794.
    View in: PubMed
    Score: 0.005
  107. Genomic Microsatellite Signatures Identify Germline Mismatch Repair Deficiency and Risk of Cancer Onset. J Clin Oncol. 2023 02 01; 41(4):766-777.
    View in: PubMed
    Score: 0.005
  108. A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation. Science. 2022 10 07; 378(6615):68-78.
    View in: PubMed
    Score: 0.005
  109. Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022 09; 609(7929):1021-1028.
    View in: PubMed
    Score: 0.005
  110. A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours. Nat Commun. 2022 07 19; 13(1):4178.
    View in: PubMed
    Score: 0.005
  111. The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors. Nat Commun. 2022 07 13; 13(1):4061.
    View in: PubMed
    Score: 0.005
  112. Mutations in SUFU predispose to medulloblastoma. Nat Genet. 2002 Jul; 31(3):306-10.
    View in: PubMed
    Score: 0.005
  113. Radiomic signatures of posterior fossa ependymoma: Molecular subgroups and risk profiles. Neuro Oncol. 2022 06 01; 24(6):986-994.
    View in: PubMed
    Score: 0.005
  114. The biology of ependymomas and?emerging novel therapies. Nat Rev Cancer. 2022 04; 22(4):208-222.
    View in: PubMed
    Score: 0.005
  115. Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency. Nat Med. 2022 01; 28(1):125-135.
    View in: PubMed
    Score: 0.005
  116. Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse. Neuro Oncol. 2022 01 05; 24(1):153-165.
    View in: PubMed
    Score: 0.005
  117. Spatial concordance of DNA methylation classification in diffuse glioma. Neuro Oncol. 2021 12 01; 23(12):2054-2065.
    View in: PubMed
    Score: 0.005
  118. Dual role of allele-specific DNA hypermethylation within the TERT promoter in cancer. J Clin Invest. 2021 11 01; 131(21).
    View in: PubMed
    Score: 0.005
  119. Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study. Clin Cancer Res. 2022 01 01; 28(1):116-128.
    View in: PubMed
    Score: 0.005
  120. Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer. Nat Commun. 2021 09 02; 12(1):5238.
    View in: PubMed
    Score: 0.005
  121. Subgroup and subtype-specific outcomes in adult medulloblastoma. Acta Neuropathol. 2021 11; 142(5):859-871.
    View in: PubMed
    Score: 0.005
  122. Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q. Neuro Oncol. 2021 08 02; 23(8):1360-1370.
    View in: PubMed
    Score: 0.005
  123. Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma. Genome Med. 2021 06 21; 13(1):103.
    View in: PubMed
    Score: 0.005
  124. Modeling human brain tumors in flies, worms, and zebrafish: From proof of principle to novel therapeutic targets. Neuro Oncol. 2021 05 05; 23(5):718-731.
    View in: PubMed
    Score: 0.005
  125. The transcriptional landscape of Shh medulloblastoma. Nat Commun. 2021 03 19; 12(1):1749.
    View in: PubMed
    Score: 0.005
  126. Mutations in the RAS/MAPK Pathway Drive Replication Repair-Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition. Cancer Discov. 2021 06; 11(6):1454-1467.
    View in: PubMed
    Score: 0.005
  127. Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma. J Clin Oncol. 2021 03 01; 39(7):807-821.
    View in: PubMed
    Score: 0.005
  128. GLI3?Is Associated With Neuronal Differentiation in SHH-Activated and WNT-Activated Medulloblastoma. J Neuropathol Exp Neurol. 2021 01 20; 80(2):129-136.
    View in: PubMed
    Score: 0.005
  129. Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival. Elife. 2021 01 11; 10.
    View in: PubMed
    Score: 0.005
  130. DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells. Cancer Discov. 2021 05; 11(5):1176-1191.
    View in: PubMed
    Score: 0.005
  131. Activated leukocyte cell adhesion molecule expression correlates with the WNT subgroup in medulloblastoma and is involved in regulating tumor cell proliferation and invasion. PLoS One. 2020; 15(12):e0243272.
    View in: PubMed
    Score: 0.005
  132. Artificial intelligence for automatic cerebral ventricle segmentation and volume calculation: a clinical tool for the evaluation of pediatric hydrocephalus. J Neurosurg Pediatr. 2021 02 01; 27(2):131-138.
    View in: PubMed
    Score: 0.005
  133. European genetic ancestry associated with risk of childhood ependymoma. Neuro Oncol. 2020 11 26; 22(11):1637-1646.
    View in: PubMed
    Score: 0.005
  134. The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization. Cell Stem Cell. 2021 03 04; 28(3):488-501.e10.
    View in: PubMed
    Score: 0.005
  135. Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma. Acta Neuropathol Commun. 2020 10 28; 8(1):173.
    View in: PubMed
    Score: 0.005
  136. Clinical impact of combined epigenetic and molecular analysis of pediatric low-grade gliomas. Neuro Oncol. 2020 10 14; 22(10):1474-1483.
    View in: PubMed
    Score: 0.005
  137. H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone. Cancer Discov. 2020 12; 10(12):1968-1987.
    View in: PubMed
    Score: 0.005
  138. Deep Learning for Pediatric Posterior Fossa Tumor Detection and Classification: A Multi-Institutional Study. AJNR Am J Neuroradiol. 2020 09; 41(9):1718-1725.
    View in: PubMed
    Score: 0.005
  139. Radiation-induced intracranial aneurysm presenting with acute hemorrhage in a child treated for medulloblastoma. Childs Nerv Syst. 2021 04; 37(4):1387-1389.
    View in: PubMed
    Score: 0.005
  140. An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate. Nat Commun. 2020 07 20; 11(1):3627.
    View in: PubMed
    Score: 0.004
  141. Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma. Cell Rep Med. 2020 06 23; 1(3).
    View in: PubMed
    Score: 0.004
  142. DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. Dev Cell. 2020 08 24; 54(4):455-470.e5.
    View in: PubMed
    Score: 0.004
  143. Eye Movements and White Matter are Associated with Emotional Control in Children Treated for Brain Tumors. J Int Neuropsychol Soc. 2020 11; 26(10):978-992.
    View in: PubMed
    Score: 0.004
  144. Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma. Cell. 2020 06 11; 181(6):1329-1345.e24.
    View in: PubMed
    Score: 0.004
  145. Reply to S.A. Milgrom et al. J Clin Oncol. 2020 07 01; 38(19):2212-2213.
    View in: PubMed
    Score: 0.004
  146. Expression of GNAS, TP53, and PTEN Improves the Patient Prognostication in Sonic Hedgehog (SHH) Medulloblastoma Subgroup. J Mol Diagn. 2020 07; 22(7):957-966.
    View in: PubMed
    Score: 0.004
  147. Roadmap for the Emerging Field of Cancer Neuroscience. Cell. 2020 04 16; 181(2):219-222.
    View in: PubMed
    Score: 0.004
  148. Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy. Nat Commun. 2020 04 14; 11(1):1825.
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  316. Somatostatin receptor subtype 2 (sst2) is a potential prognostic marker and a therapeutic target in medulloblastoma. Childs Nerv Syst. 2013 Aug; 29(8):1253-62.
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  320. DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies. Acta Neuropathol. 2013 Mar; 125(3):359-71.
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  321. MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma. J Biol Chem. 2013 Jan 18; 288(3):1918-28.
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  322. Medulloblastomics: the end of the beginning. Nat Rev Cancer. 2012 Dec; 12(12):818-34.
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  323. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell. 2012 Oct 16; 22(4):425-37.
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  324. Bmi1 overexpression in the cerebellar granule cell lineage of mice affects cell proliferation and survival without initiating medulloblastoma formation. Dis Model Mech. 2013 Jan; 6(1):49-63.
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  325. Canonical TGF-? pathway activity is a predictor of SHH-driven medulloblastoma survival and delineates putative precursors in cerebellar development. Brain Pathol. 2013 Mar; 23(2):178-91.
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  326. The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis. Am J Pathol. 2012 Nov; 181(5):1762-72.
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  327. Clinical and neuroanatomical predictors of cerebellar mutism syndrome. Neuro Oncol. 2012 Oct; 14(10):1294-303.
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  328. Functional genomics identifies drivers of medulloblastoma dissemination. Cancer Res. 2012 Oct 01; 72(19):4944-53.
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  329. Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature. 2012 Aug 02; 488(7409):106-10.
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  330. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 2012 Aug 02; 488(7409):49-56.
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  331. Dissecting the genomic complexity underlying medulloblastoma. Nature. 2012 Aug 02; 488(7409):100-5.
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  332. Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev. 2012 Aug 15; 26(16):1780-96.
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  333. Targeting the enhancer of zeste homologue 2 in medulloblastoma. Int J Cancer. 2012 Oct 15; 131(8):1800-9.
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  334. Nestin expression identifies ependymoma patients with poor outcome. Brain Pathol. 2012 Nov; 22(6):848-60.
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  335. Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC. Cancer Cell. 2012 May 15; 21(5):601-613.
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  336. Multiple CDK/CYCLIND genes are amplified in medulloblastoma and supratentorial primitive neuroectodermal brain tumor. Cancer Genet. 2012 May; 205(5):220-31.
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  337. Matching mice to malignancy: molecular subgroups and models of medulloblastoma. Childs Nerv Syst. 2012 Apr; 28(4):521-32.
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  338. Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells. BMC Cancer. 2012 Mar 05; 12:80.
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  339. Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas. Acta Neuropathol. 2012 Apr; 123(4):473-84.
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  340. Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell. 2012 Jan 20; 148(1-2):59-71.
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  341. Survival benefit for pediatric patients with recurrent ependymoma treated with reirradiation. Int J Radiat Oncol Biol Phys. 2012 Aug 01; 83(5):1541-8.
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  342. Biological and clinical heterogeneity of MYCN-amplified medulloblastoma. Acta Neuropathol. 2012 Apr; 123(4):515-27.
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  343. Monoallelic expression determines oncogenic progression and outcome in benign and malignant brain tumors. Cancer Res. 2012 Feb 01; 72(3):636-44.
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  344. MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma. Acta Neuropathol. 2012 Apr; 123(4):529-38.
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  345. Association between left ventricular mass index and cardiac function in pediatric dialysis patients. Pediatr Nephrol. 2012 May; 27(5):835-41.
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  346. FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma. J Clin Oncol. 2011 Oct 10; 29(29):3852-61.
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  347. Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell. 2011 Aug 16; 20(2):143-57.
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  348. Adult medulloblastoma comprises three major molecular variants. J Clin Oncol. 2011 Jul 01; 29(19):2717-23.
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  349. Neurosurgical management of extraaxial central nervous system infections in children. J Neurosurg Pediatr. 2011 May; 7(5):441-51.
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  350. Rapid diagnosis of medulloblastoma molecular subgroups. Clin Cancer Res. 2011 Apr 01; 17(7):1883-94.
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  351. The genetic landscape of the childhood cancer medulloblastoma. Science. 2011 Jan 28; 331(6016):435-9.
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  353. Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma. Cancer Res. 2010 Oct 15; 70(20):8003-14.
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  354. Silencing of thrombospondin-1 is critical for myc-induced metastatic phenotypes in medulloblastoma. Cancer Res. 2010 Oct 15; 70(20):8199-210.
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  355. Posterior fossa ependymomas: new radiological classification with surgical correlation. Childs Nerv Syst. 2010 Dec; 26(12):1765-72.
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  357. Use of ifosfamide, carboplatin, and etoposide chemotherapy in choroid plexus carcinoma. J Neurosurg Pediatr. 2010 Jun; 5(6):615-21.
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  358. Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15; 24(10):1059-72.
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  359. HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth. Clin Cancer Res. 2010 Jun 15; 16(12):3240-52.
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  361. Universal poor survival in children with medulloblastoma harboring somatic TP53 mutations. J Clin Oncol. 2010 Mar 10; 28(8):1345-50.
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  362. OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas. Cancer Res. 2010 Jan 01; 70(1):181-91.
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  363. Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors. Cancer Cell. 2009 Dec 08; 16(6):533-46.
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  364. Normal and oncogenic roles for microRNAs in the developing brain. Cell Cycle. 2009 Dec 15; 8(24):4049-54.
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  365. YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes Dev. 2009 Dec 01; 23(23):2729-41.
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  366. MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. PLoS One. 2009; 4(3):e4998.
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  367. An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma. Cancer Res. 2008 Dec 01; 68(23):9945-53.
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  368. Expression of MAGE and GAGE genes in medulloblastoma and modulation of resistance to chemotherapy. Laboratory investigation. J Neurosurg Pediatr. 2008 Apr; 1(4):305-13.
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  369. The history of neurosurgery at the Hospital for Sick Children in Toronto. Neurosurgery. 2007 Sep; 61(3):612-24; discussion 624-5.
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  370. Incorporation of C-1 lateral mass screws in occipitocervical and atlantoaxial fusions for children 8 years of age or younger. Technical note. J Neurosurg. 2007 Aug; 107(2 Suppl):178-83.
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  371. Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J Clin Oncol. 2006 Apr 20; 24(12):1924-31.
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