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DAFEI CHAI

TitleInstructor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li W, Wang R, Wang J, Chai D, Xie X, Young KHH, Cao Y, Li Y, Yu X. Lasalocid A selectively induces the degradation of MYD88 in lymphomas harboring the MYD88 L265P mutation. Blood. 2024 Nov 22. PMID: 39576960.
      Citations:    Fields:    
    2. Neeli P, Chai D, Wang X, Sobhani N, Udeani G, Li Y. Erratum: Comparison of DNA vaccines with AddaS03 as an adjuvant and an mRNA vaccine against SARS-CoV-2. iScience. 2024 Oct 18; 27(10):110969. PMID: 39474074; PMCID: PMC11519417.
      Citations:    
    3. Neeli P, Maza PAMA, Chai D, Zhao D, Hoi XP, Chan KS, Young KH, Li Y. DNA vaccines against GPRC5D synergize with PD-1 blockade to treat multiple myeloma. NPJ Vaccines. 2024 Oct 01; 9(1):180. PMID: 39353958; PMCID: PMC11445568.
      Citations:    
    4. Zheng Y, Lu Z, Zhu F, Zhao G, Shao Y, Lu B, Ding J, Wang G, Fang L, Zheng J, Chai D. Therapeutic vaccine targeting dual immune checkpoints induces potent multifunctional CD8+ T cell anti-tumor immunity. Int Immunopharmacol. 2024 Dec 05; 142(Pt A):113004. PMID: 39217885.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Zhu F, Lu Z, Tang W, Zhao G, Shao Y, Lu B, Ding J, Zheng Y, Fang L, Li H, Wang G, Chen R, Zheng J, Chai D. Adenovirus vaccine targeting kinases induces potent antitumor immunity in solid tumors. J Immunother Cancer. 2024 Aug 28; 12(8). PMID: 39209449; PMCID: PMC11367354.
      Citations:    Fields:    Translation:HumansAnimalsCells
    6. Chai D, Wang J, Fan C, Lim JM, Wang X, Neeli P, Yu X, Young KH, Li Y. Remodeling of anti-tumor immunity with antibodies targeting a p53 mutant. J Hematol Oncol. 2024 06 18; 17(1):45. PMID: 38886748; PMCID: PMC11184848.
      Citations:    Fields:    Translation:HumansAnimalsCells
    7. Lu B, Lim JM, Yu B, Song S, Neeli P, Sobhani N, K P, Bonam SR, Kurapati R, Zheng J, Chai D. The next-generation DNA vaccine platforms and delivery systems: advances, challenges and prospects. Front Immunol. 2024; 15:1332939. PMID: 38361919; PMCID: PMC10867258.
      Citations: 11     Fields:    Translation:HumansAnimals
    8. Sobhani N, Tardiel-Cyril DR, Chai D, Generali D, Li JR, Vazquez-Perez J, Lim JM, Morris R, Bullock ZN, Davtyan A, Cheng C, Decker WK, Li Y. Artificial intelligence-powered discovery of small molecules inhibiting CTLA-4 in cancer. BJC Rep. 2024; 2. PMID: 38312352; PMCID: PMC10838660.
      Citations: 3     
    9. Jiang N, Zheng Y, Ding J, Wang J, Zhu F, Wang M, Sobhani N, Neeli P, Wang G, Li H, Zheng J, Chai D. The co-delivery of adenovirus-based immune checkpoint vaccine elicits a potent anti-tumor effect in renal carcinoma. NPJ Vaccines. 2023 Aug 04; 8(1):109. PMID: 37542081; PMCID: PMC10403580.
      Citations:    
    10. Zhou S, Chai D, Wang X, Neeli P, Yu X, Davtyan A, Young K, Li Y. AI-powered discovery of a novel p53-Y220C reactivator. Front Oncol. 2023; 13:1229696. PMID: 37593097; PMCID: PMC10430779.
      Citations: 1     
    11. Chai D, Wang X, Neeli P, Zhou S, Yu X, Sabapathy K, Li Y. DNA-delivered monoclonal antibodies targeting the p53 R175H mutant epitope inhibit tumor development in mice. Genes Dis. 2024 Jul; 11(4):100994. PMID: 38560504; PMCID: PMC10980946.
      Citations: 1     
    12. Neeli P, Chai D, Wang X, Sobhani N, Udeani G, Li Y. Comparison of DNA vaccines with AddaS03 as an adjuvant and an mRNA vaccine against SARS-CoV-2. iScience. 2023 Jul 21; 26(7):107120. PMID: 37361876; PMCID: PMC10271916.
      Citations: 1     
    13. Shi X, Ding J, Zheng Y, Wang J, Sobhani N, Neeli P, Wang G, Zheng J, Chai D. HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8+T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma. iScience. 2023 Mar 17; 26(3):106143. PMID: 36879804; PMCID: PMC9984564.
      Citations:    
    14. Wang Q, Chai D, Sobhani N, Sun N, Neeli P, Zheng J, Tian H. C1QBP regulates mitochondrial plasticity to impact tumor progression and antitumor immune response. Front Physiol. 2022; 13:1012112. PMID: 36467687; PMCID: PMC9713694.
      Citations:    
    15. Zheng Y, Lu Z, Ding J, Jiang N, Wang J, Yang J, Song J, Chen H, Fang L, Li H, Tian H, Wang G, Zheng J, Chai D. Therapeutic Adenovirus Vaccine Combined Immunization with IL-12 Induces Potent CD8+ T Cell Anti-Tumor Immunity in Hepatocellular Carcinoma. Cancers (Basel). 2022 Sep 17; 14(18). PMID: 36139670; PMCID: PMC9497125.
      Citations:    
    16. Sobhani N, Scaggiante B, Morris R, Chai D, Catalano M, Tardiel-Cyril DR, Neeli P, Roviello G, Mondani G, Li Y. Therapeutic cancer vaccines: From biological mechanisms and engineering to ongoing clinical trials. Cancer Treat Rev. 2022 Sep; 109:102429. PMID: 35759856; PMCID: PMC9217071.
      Citations:    Fields:    
    17. Sobhani N, Chahwan R, Roudi R, Morris R, Chai D, D'Angelo A, Generali D, Volinia S. Predictive and Prognostic Value of Non-Coding RNA in Breast Cancer. Cancers (Basel). 2022 Jun 15; 14(12). PMID: 35740618; PMCID: PMC9221286.
      Citations:    
    18. Chai D, Shi SY, Sobhani N, Ding J, Zhang Z, Jiang N, Wang G, Li M, Li H, Zheng J, Bai J. IFI35 Promotes Renal Cancer Progression by Inhibiting pSTAT1/pSTAT6-Dependent Autophagy. Cancers (Basel). 2022 Jun 09; 14(12). PMID: 35740527; PMCID: PMC9221357.
      Citations:    
    19. Chai D, Qiu D, Shi X, Ding J, Jiang N, Zhang Z, Wang J, Yang J, Xiao P, Wang G, Zheng J. Dual-targeting vaccine of FGL1/CAIX exhibits potent anti-tumor activity by activating DC-mediated multi-functional CD8 T?cell immunity. Mol Ther Oncolytics. 2022 Mar 17; 24:1-13. PMID: 34977338; PMCID: PMC8688948.
      Citations:    
    20. Sun H, Li J, Hu W, Yan Y, Guo Z, Zhang Z, Chen Y, Yao X, Teng L, Wang X, Li L, Chai D, Zheng J, Wang G. Co-immunizing with HMGB1 enhances anti-tumor immunity of B7H3 vaccine in renal carcinoma. Mol Immunol. 2021 11; 139:184-192. PMID: 34560414.
      Citations:    
    21. Chai D, Zhang Z, Jiang N, Ding J, Qiu D, Shi SY, Wang G, Fang L, Li H, Tian H, Yang J, Zhang Q, Zheng J. Co-immunization with L-Myc enhances CD8+ or CD103+ DCs mediated tumor-specific multi-functional CD8+ T cell responses. Cancer Sci. 2021 Sep; 112(9):3469-3483. PMID: 34157192; PMCID: PMC8409417.
      Citations:    
    22. Chai D, Shan H, Wang G, Zhang Q, Li H, Fang L, Song J, Liu N, Zhang Q, Yao H, Zheng J. Combining DNA Vaccine and AIM2 in H1 Nanoparticles Exert Anti-Renal Carcinoma Effects via Enhancing Tumor-Specific Multi-functional CD8+ T-cell Responses. Mol Cancer Ther. 2019 02; 18(2):323-334. PMID: 30401695.
      Citations:    
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