Chandra Bhushan Mishra to Humans
This is a "connection" page, showing publications Chandra Bhushan Mishra has written about Humans.
Connection Strength
0.303
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Synthesis, Structure-Activity Relationships, and Antitumor Activities of Quinoxiline-Containing Inhibitors of the Protein-Protein Interactions between Transcription Coactivator AF9/ENL and DOT1L/AF4. J Med Chem. 2025 Sep 25; 68(18):19396-19414.
Score: 0.025
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Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation. Biomed Pharmacother. 2024 May; 174:116484.
Score: 0.023
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Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004): in?vitro and in?vivo studies. J Enzyme Inhib Med Chem. 2021 Dec; 36(1):954-963.
Score: 0.019
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Identifying the natural polyphenol catechin as a multi-targeted agent against SARS-CoV-2 for the plausible therapy of COVID-19: an integrated computational approach. Brief Bioinform. 2021 03 22; 22(2):1346-1360.
Score: 0.019
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Discovery of Potent Carbonic Anhydrase Inhibitors as Effective Anticonvulsant Agents: Drug Design, Synthesis, and In Vitro and In Vivo Investigations. J Med Chem. 2021 03 25; 64(6):3100-3114.
Score: 0.018
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Development of novel carbazole derivatives with effective multifunctional action against Alzheimer's diseases: Design, synthesis, in silico, in vitro and in vivo investigation. Bioorg Chem. 2020 01; 95:103524.
Score: 0.017
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Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in?vitro and in?vivo appraisal. Eur J Med Chem. 2018 Aug 05; 156:430-443.
Score: 0.015
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Discovery of novel Methylsulfonyl phenyl derivatives as potent human Cyclooxygenase-2 inhibitors with effective anticonvulsant action: Design, synthesis, in-silico, in-vitro and in-vivo evaluation. Eur J Med Chem. 2018 May 10; 151:520-532.
Score: 0.015
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Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation. J Med Chem. 2018 04 12; 61(7):3151-3165.
Score: 0.015
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Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. J Med Chem. 2017 03 23; 60(6):2456-2469.
Score: 0.014
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Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease. Eur J Med Chem. 2017 Jan 05; 125:736-750.
Score: 0.014
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Design, synthesis and biological evaluation of N-(5-methyl-isoxazol-3-yl/1,3,4-thiadiazol-2-yl)-4-(3-substitutedphenylureido) benzenesulfonamides as human carbonic anhydrase isoenzymes I, II, VII and XII inhibitors. J Enzyme Inhib Med Chem. 2016; 31(sup2):174-179.
Score: 0.013
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Design, synthesis and evaluation of novel indandione derivatives as multifunctional agents with cholinesterase inhibition, anti-?-amyloid aggregation, antioxidant and neuroprotection properties against Alzheimer's disease. Bioorg Med Chem. 2016 08 15; 24(16):3829-41.
Score: 0.013
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Thiazole: a promising heterocycle for the development of potent CNS active agents. Eur J Med Chem. 2015 Mar 06; 92:1-34.
Score: 0.012
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Design and synthesis of (4E)-4-(4-substitutedbenzylideneamino)-3-substituted-2,3-dihydro-2-thioxothiazole-5-carbonitrile as novel A2A receptor antagonists. Bioorg Med Chem. 2013 Oct 01; 21(19):6077-83.
Score: 0.011
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Novel 8-(furan-2-yl)-3-substituted thiazolo [5,4-e][1,2,4] triazolo[1,5-c] pyrimidine-2(3H)-thione derivatives as potential adenosine A(2A) receptor antagonists. Bioorg Med Chem. 2010 Apr 01; 18(7):2491-500.
Score: 0.009
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Heterogeneous Folding Intermediates Govern the Conformational Pathway of the RNA Recognition Motif Domain of the Ewing Sarcoma Protein. Biomolecules. 2025 12 24; 16(1).
Score: 0.006
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Design and Synthesis of Potent and Selective Urea-linked Benzenesulfonamide Analogs as Carbonic Anhydrase II Inhibitors. Eur J Pharm Sci. 2025 Oct 01; 213:107233.
Score: 0.006
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Development of carbazole-based molecules for inhibition of mutant hSOD1 protein aggregation in Amyotrophic Lateral Sclerosis. Bioorg Med Chem. 2025 Apr 01; 120:118091.
Score: 0.006
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Design, Synthesis, X-ray Crystallography, and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease. ACS Infect Dis. 2024 02 09; 10(2):715-731.
Score: 0.006
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Quinazolinone Compounds Have Potent Antiviral Activity against Zika and Dengue Virus. J Med Chem. 2023 08 10; 66(15):10746-10760.
Score: 0.005
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Emerging Importance of Tyrosine Kinase Inhibitors against Cancer: Quo Vadis to Cure? Int J Mol Sci. 2021 Oct 28; 22(21).
Score: 0.005
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Design, synthesis, in silico and biological evaluation of novel 2-(4-(4-substituted piperazin-1-yl)benzylidene)hydrazine carboxamides. Mol Divers. 2017 Feb; 21(1):163-174.
Score: 0.003
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Polypharmacological Drugs in the Treatment of Epilepsy: The Comprehensive Review of Marketed and New Emerging Molecules. Curr Pharm Des. 2016; 22(21):3212-25.
Score: 0.003
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8-(Furan-2-yl)-3-phenethylthiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thione as novel, selective and potent adenosine A(2A) receptor antagonist. Neurosci Lett. 2014 Jan 13; 558:203-7.
Score: 0.003
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Novel 8-(furan-2-yl)-3-benzyl thiazolo [5,4-e][1,2,4] triazolo [1,5-c] pyrimidine-2(3H)-thione as selective adenosine A(2A) receptor antagonist. Neurosci Lett. 2011 Jan 13; 488(1):1-5.
Score: 0.002
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Synthesis of novel 7-imino-2-thioxo-3,7-dihydro-2H-thiazolo [4,5-d] pyrimidine derivatives as adenosine A2A receptor antagonists. Bioorg Med Chem Lett. 2010 Feb 01; 20(3):1214-8.
Score: 0.002
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In silico study of naphtha [1, 2-d] thiazol-2-amine with adenosine A 2A receptor and its role in antagonism of haloperidol-induced motor impairments in mice. Neurosci Lett. 2009 Oct 09; 463(3):215-8.
Score: 0.002