Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors.

Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors. Prog Biophys Mol Biol. 2021 08; 163:171-186.

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subject areas

Amino Acid Sequence
Antiviral Agents
Catalytic Domain
Crystallography, X-Ray
Drug Discovery
Enzyme Inhibitors
Glycoside Hydrolases
Humans
Models, Molecular
Protein Domains
Small Molecule Libraries
Structure-Activity Relationship
Xanthines

authors with profiles

OLIVIER LICHTARGE
PANAGIOTIS KATSONIS
TODD M LINK
ZAMAL AHMED
JOHN TAINER