CHRISTOPHERWALKEYCHRISTOPHER WALKEY15266WALKEY, CHRISTOPHERInstructorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:orcidIdORCID idvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonEpigenetics & Molecular CarcinogenesisMD AndersonXUETONGSHENXUETONG SHEN9050SHEN, XUETONGAssociate ProfessorBLAINEBARTHOLOMEWBLAINE BARTHOLOMEW9892BARTHOLOMEW, BLAINEProfessorSHARON RDENTSHARON R DENT8542DENT, SHARON RProfessor74Professor54Instructor14Associate Professor78Professor Emeritus27270415Palmer EE, Jarrett KE, Sachdev RK, Al Zahrani F, Hashem MO, Ibrahim N, Sampaio H, Kandula T, Macintosh R, Gupta R, Conlon DM, Billheimer JT, Rader DJ, Funato K, Walkey CJ, Lee CS, Loo C, Brammah S, Elakis G, Zhu Y, Buckley M, Kirk EP, Bye A, Alkuraya FS, Roscioli T, Lagor WRHuman molecular geneticsNeuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy. Hum Mol Genet. 2016 07 15; 25(14):3042-3054.Hum Mol Genet2016-06-06T00:00:002016Neuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy.MARCODE GIORGIMARCO DE GIORGI12815DE GIORGI, MARCOInstructor28415573Johnson SAS, Lin JJ, Walkey CJ, Leathers MP, Coarfa C, Johnson DLOncotargetElevated TATA-binding protein expression drives vascular endothelial growth factor expression in colon cancer. Oncotarget. 2017 Jul 25; 8(30):48832-48845.Oncotarget2017-07-25T00:00:002017Elevated TATA-binding protein expression drives vascular endothelial growth factor expression in colon cancer.D012441Living Beings2206200.736866Saccharomyces cerevisiaeD013312Physiology2904980.749263Stress, PhysiologicalD029701Chemicals & Drugs1514430.757974Saccharomyces cerevisiae ProteinsD014920Objects15190.985297WineD005285Physiology32600.978876Fermentation30110641Chen CY, Lanz RB, Walkey CJ, Chang WH, Lu W, Johnson DLCell reportsMaf1 and Repression of RNA Polymerase III-Mediated Transcription Drive Adipocyte Differentiation. Cell Rep. 2018 08 14; 24(7):1852-1864.Cell Rep2018-08-14T00:00:002018Maf1 and Repression of RNA Polymerase III-Mediated Transcription Drive Adipocyte Differentiation.Department of Molecular & Cellular BiologyDepartment of Molecular & Human GeneticsMolecular & Cellular BiologyMolecular & Human GeneticsMolecular Physiology & BiophysicsBaylor College of MedicineJAMESMARTINJAMES MARTIN0.000000000000000.000000000000001889MARTIN, JAMESProfessorJASONHEANEYJASON HEANEY29.71073630000000-95.396604500000004093HEANEY, JASONAssociate ProfessorWEIWEIDANGWEIWEI DANG0.000000000000000.000000000000004794DANG, WEIWEI0000-0002-6931-4636Associate ProfessorGRZEGORZIRAGRZEGORZ IRA29.71073630000000-95.39660450000000927IRA, GRZEGORZProfessorWILLIAMLAGORWILLIAM LAGOR0.000000000000000.000000000000004763LAGOR, WILLIAMProfessor31645432Wang X, Rusin A, Walkey CJ, Lin JJ, Johnson DLThe Journal of biological chemistryThe RNA polymerase III repressor MAF1 is regulated by ubiquitin-dependent proteasome degradation and modulates cancer drug resistance and apoptosis. J Biol Chem. 2019 12 13; 294(50):19255-19268.J Biol Chem2019-10-23T00:00:002019The RNA polymerase III repressor MAF1 is regulated by ubiquitin-dependent proteasome degradation and modulates cancer drug resistance and apoptosis.true1ProfessorProfessortrue1Associate ProfessorAssociate ProfessorOne Baylor PlazaHouston, 77030TX0.8173170.00401446144research areas1.677130.039365110coauthor of12.84711.9406360similar to1119selected publicationsAuthorship 9665354Authorship 9690891Authorship 9696261Authorship 9704961Authorship 9707402Authorship 9710402Authorship 9716042Authorship 97308215Authorship 9732003Authorship 9736473Authorship 974386323692528Luo Z, Walkey CJ, Madilao LL, Measday V, Van Vuuren HJFEMS yeast researchFunctional improvement of Saccharomyces cerevisiae to reduce volatile acidity in wine. FEMS Yeast Res. 2013 Aug; 13(5):485-94.FEMS Yeast Res2013-06-13T00:00:002013Functional improvement of Saccharomyces cerevisiae to reduce volatile acidity in wine.18622018Walkey CJ, Spiegelman BMThe Journal of biological chemistryA functional peroxisome proliferator-activated receptor-gamma ligand-binding domain is not required for adipogenesis. J Biol Chem. 2008 Sep 05; 283(36):24290-4.J Biol Chem2008-07-11T00:00:002008A functional peroxisome proliferator-activated receptor-gamma ligand-binding domain is not required for adipogenesis.21585652Walkey CJ, Luo Z, Borchers CH, Measday V, van Vuuren HJFEMS yeast researchThe Saccharomyces cerevisiae fermentation stress response protein Igd1p/Yfr017p regulates glycogen levels by inhibiting the glycogen debranching enzyme. FEMS Yeast Res. 2011 Sep; 11(6):499-508.FEMS Yeast Res2011-06-16T00:00:002011The Saccharomyces cerevisiae fermentation stress response protein Igd1p/Yfr017p regulates glycogen levels by inhibiting the glycogen debranching enzyme.12754525Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BMNatureInsulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature. 2003 May 29; 423(6939):550-5.Nature2003-05-18T00:00:002003Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.24130853Bessonov K, Walkey CJ, Shelp BJ, van Vuuren HJ, Chiu D, van der Merwe GPloS oneFunctional analyses of NSF1 in wine yeast using interconnected correlation clustering and molecular analyses. PLoS One. 2013; 8(10):e77192.PLoS One2013-10-09T00:00:002013Functional analyses of NSF1 in wine yeast using interconnected correlation clustering and molecular analyses.26471523Liu Y, Walkey CJ, Green TJ, van Vuuren HJ, Kitts DDFood chemistryEnhancing the natural folate level in wine using bioengineering and stabilization strategies. Food Chem. 2016 Mar 01; 194:26-31.Food Chem2015-07-30T00:00:002015Enhancing the natural folate level in wine using bioengineering and stabilization strategies.23240040Walkey CJ, Luo Z, Madilao LL, van Vuuren HJPloS oneThe fermentation stress response protein Aaf1p/Yml081Wp regulates acetate production in Saccharomyces cerevisiae. PLoS One. 2012; 7(12):e51551.PLoS One2012-12-11T00:00:002012The fermentation stress response protein Aaf1p/Yml081Wp regulates acetate production in Saccharomyces cerevisiae.Authorship 977965232060938Wang X, Walkey CJ, Maretti-Mira AC, Wang L, Johnson DL, DeLeve LDHepatology (Baltimore, Md.)Susceptibility of Rat Steatotic Liver to Ischemia-Reperfusion Is Treatable With Liver-Selective Matrix Metalloproteinase Inhibition. Hepatology. 2020 11; 72(5):1771-1785.Hepatology2020-10-22T00:00:002020Susceptibility of Rat Steatotic Liver to Ischemia-Reperfusion Is Treatable With Liver-Selective Matrix Metalloproteinase Inhibition.Authorship 978064232073405Doerfler AM, Walkey CJ, Lagor WRCurrent opinion in cardiologyRecent advances in genome editing for cardiovascular disease. Curr Opin Cardiol. 2020 05; 35(3):242-248.Curr Opin Cardiol2020-05-01T00:00:002020Recent advances in genome editing for cardiovascular disease.Authorship 1032360234695545Liang SQ, Walkey CJ, Martinez AE, Su Q, Dickinson ME, Wang D, Lagor WR, Heaney JD, Gao G, Xue WMolecular therapy : the journal of the American Society of Gene TherapyAAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway. Mol Ther. 2022 Jan 05; 30(1):238-243.Mol Ther2021-10-23T00:00:002021AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway.Authorship 1046559535611941Phillips E, Ahmad N, Sun L, Iben J, Walkey CJ, Rusin A, Yuen T, Rosen CJ, Willis IM, Zaidi M, Johnson DLeLifeMAF1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass. Elife. 2022 05 25; 11.Elife2022-05-25T00:00:002022MAF1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass.true1InstructorInstructortrue1ProfessorProfessorDepartment of Integrative Physiologytrue1InstructorInstructorAuthorship 1062479336587560Lorincz R, Alvarez AB, Walkey CJ, Mendon?a SA, Lu ZH, Martinez AE, Ljungberg C, Heaney JD, Lagor WR, Curiel DTBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieIn vivo editing of the pan-endothelium by immunity evading simian adenoviral vector. Biomed Pharmacother. 2023 Feb; 158:114189.Biomed Pharmacother2022-12-30T00:00:002022In vivo editing of the pan-endothelium by immunity evading simian adenoviral vector.Authorship 1068951137065676Walkey CJ, Lagor WRThe journal of cardiovascular agingCaMKIId gene editing- A base hit for the heart. J Cardiovasc Aging. 2023; 3(2).J Cardiovasc Aging2023-03-22T00:00:002023CaMKIId gene editing- A base hit for the heart.Authorship 10749311337467291Huang Q, Chen AT, Chan KY, Sorensen H, Barry AJ, Azari B, Zheng Q, Beddow T, Zhao B, Tobey IG, Moncada-Reid C, Eid FE, Walkey CJ, Ljungberg MC, Lagor WR, Heaney JD, Chan YA, Deverman BEPLoS biologyTargeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier. PLoS Biol. 2023 07; 21(7):e3002112.PLoS Biol2023-07-19T00:00:002023Targeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier.true1ProfessorProfessortrue1Associate ProfessorAssociate ProfessorAuthorship 1079266837546995De Giorgi M, Park SH, Castoreno A, Cao M, Hurley A, Saxena L, Chuecos MA, Walkey CJ, Doerfler AM, Furgurson MN, Ljungberg MC, Patel KR, Hyde S, Chickering T, Lefebvre S, Wassarman K, Miller P, Qin J, Schlegel MK, Zlatev I, Li RG, Kim J, Martin JF, Bissig KD, Jadhav V, Bao G, Lagor WRbioRxiv : the preprint server for biologyIn vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene. bioRxiv. 2023 Jul 29.bioRxiv2023-07-29T00:00:002023In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene.true1Professor EmeritusProfessor Emeritustrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessorDEBORAHJOHNSONDEBORAH JOHNSON7118JOHNSON, DEBORAHProfessor Emeritus