IVANGORLOVIVAN GORLOV15244GORLOV, IVANAssociate Professorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson21044312Gorlov IP, Sircar K, Zhao H, Maity SN, Navone NM, Gorlova OY, Troncoso P, Pettaway CA, Byun JY, Logothetis CJBMC cancerPrioritizing genes associated with prostate cancer development. BMC Cancer. 2010 Nov 02; 10:599.BMC Cancer2010-11-02T00:00:002010Prioritizing genes associated with prostate cancer development.22809348Gorlov IP, Byun J, Zhao H, Logothetis CJ, Gorlova OYJournal of bioinformatics and computational biologyBeyond comparing means: the usefulness of analyzing interindividual variation in gene expression for identifying genes associated with cancer development. J Bioinform Comput Biol. 2012 Apr; 10(2):1241013.J Bioinform Comput Biol2012-04-01T00:00:002012Beyond comparing means: the usefulness of analyzing interindividual variation in gene expression for identifying genes associated with cancer development.EpidemiologyGenitourinary Medical OncologyMD AndersonXIFENGWUXIFENG WU8625WU, XIFENGProfessorCHRISTOPHER JLOGOTHETISCHRISTOPHER J LOGOTHETIS8480LOGOTHETIS, CHRISTOPHER JProfessor19551858Byun J, Logothetis CJ, Gorlov IPInternational journal of cancerHousekeeping genes in prostate tumorigenesis. Int J Cancer. 2009 Dec 01; 125(11):2603-8.Int J Cancer2009-12-01T00:00:002009Housekeeping genes in prostate tumorigenesis.19653896Gorlov IP, Byun J, Gorlova OY, Aparicio AM, Efstathiou E, Logothetis CJBMC medical genomicsCandidate pathways and genes for prostate cancer: a meta-analysis of gene expression data. BMC Med Genomics. 2009 Aug 04; 2:48.BMC Med Genomics2009-08-04T00:00:002009Candidate pathways and genes for prostate cancer: a meta-analysis of gene expression data.22593245Gorlov IP, Byun J, Logothetis CJCancer genomics & proteomicsIn silico functional profiling of individual prostate cancer tumors: many genes, few functions. Cancer Genomics Proteomics. 2012 May-Jun; 9(3):109-14.Cancer Genomics Proteomics2012-05-01T00:00:002012In silico functional profiling of individual prostate cancer tumors: many genes, few functions.23166609Gorlov IP, Logothetis CJ, Fang S, Gorlova OY, Amos CPloS oneBuilding a statistical model for predicting cancer genes. PLoS One. 2012; 7(11):e49175.PLoS One2012-11-15T00:00:002012Building a statistical model for predicting cancer genes.20639879Hirschfield GM, Liu X, Han Y, Gorlov IP, Lu Y, Xu C, Lu Y, Chen W, Juran BD, Coltescu C, Mason AL, Milkiewicz P, Myers RP, Odin JA, Luketic VA, Speiciene D, Vincent C, Levy C, Gregersen PK, Zhang J, Heathcote EJ, Lazaridis KN, Amos CI, Siminovitch KANature geneticsVariants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis. Nat Genet. 2010 Aug; 42(8):655-7.Nat Genet2010-07-18T00:00:002010Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis.22412901Chen X, Gorlov IP, Ying J, Merriman KW, Kimmel M, Lu C, Reyes-Gibby CC, Gorlova OYPloS oneInitial medical attention on patients with early-stage non-small cell lung cancer. PLoS One. 2012; 7(3):e32644.PLoS One2012-03-07T00:00:002012Initial medical attention on patients with early-stage non-small cell lung cancer.24629165Gorlova O, Fedorov A, Logothetis C, Amos C, Gorlov IBMC evolutionary biologyGenes with a large intronic burden show greater evolutionary conservation on the protein level. BMC Evol Biol. 2014 Mar 16; 14(1):50.BMC Evol Biol2014-03-16T00:00:002014Genes with a large intronic burden show greater evolutionary conservation on the protein level.24656147Gorlov IP, Yang JY, Byun J, Logothetis C, Gorlova OY, Do KA, Amos CBMC genomicsHow to get the most from microarray data: advice from reverse genomics. BMC Genomics. 2014 Mar 21; 15:223.BMC Genomics2014-03-21T00:00:002014How to get the most from microarray data: advice from reverse genomics.24367394Zhao H, Logothetis CJ, Gorlov IP, Zeng J, Dai JComputational and mathematical methods in medicineModified logistic regression models using gene coexpression and clinical features to predict prostate cancer progression. Comput Math Methods Med. 2013; 2013:917502.Comput Math Methods Med2013-12-04T00:00:002013Modified logistic regression models using gene coexpression and clinical features to predict prostate cancer progression.19652704Gorlov IP, Gallick GE, Gorlova OY, Amos C, Logothetis CJPloS oneGWAS meets microarray: are the results of genome-wide association studies and gene-expression profiling consistent? Prostate cancer as an example. PLoS One. 2009 Aug 04; 4(8):e6511.PLoS One2009-08-04T00:00:002009GWAS meets microarray: are the results of genome-wide association studies and gene-expression profiling consistent? Prostate cancer as an example.12217959Gorlov IP, Kamat A, Bogatcheva NV, Jones E, Lamb DJ, Truong A, Bishop CE, McElreavey K, Agoulnik AIHuman molecular geneticsMutations of the GREAT gene cause cryptorchidism. Hum Mol Genet. 2002 Sep 15; 11(19):2309-18.Hum Mol Genet2002-09-15T00:00:002002Mutations of the GREAT gene cause cryptorchidism.74Professor10Assistant Professor14Associate Professor42Director78Professor Emeritus6Adjunct ProfessorMedicine-Epidemiology & Populat Sci27322462Kim J, Davis JW, Klein EA, Magi-Galluzzi C, Lotan Y, Ward JF, Pisters LL, Basler JW, Pettaway CA, Stephenson A, Li Ning Tapia EM, Efstathiou E, Wang X, Do KA, Lee JJ, Gorlov IP, Vornik LA, Hoque AM, Prokhorova IN, Parnes HL, Lippman SM, Thompson IM, Brown PH, Logothetis CJ, Troncoso PEBioMedicineTissue Effects in a Randomized Controlled Trial of Short-term Finasteride in Early Prostate Cancer. EBioMedicine. 2016 May; 7:85-93.EBioMedicine2016-04-07T00:00:002016Tissue Effects in a Randomized Controlled Trial of Short-term Finasteride in Early Prostate Cancer.18179889Gorlov IP, Gorlova OY, Sunyaev SR, Spitz MR, Amos CIAmerican journal of human geneticsShifting paradigm of association studies: value of rare single-nucleotide polymorphisms. Am J Hum Genet. 2008 Jan; 82(1):100-12.Am J Hum Genet2008-01-01T00:00:002008Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms.18385676Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, Eisen T, Dong Q, Zhang Q, Gu X, Vijayakrishnan J, Sullivan K, Matakidou A, Wang Y, Mills G, Doheny K, Tsai YY, Chen WV, Shete S, Spitz MR, Houlston RSNature geneticsGenome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet. 2008 May; 40(5):616-22.Nat Genet2008-04-02T00:00:002008Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.21645942Chen X, Gorlov IP, Merriman KW, Weng SF, Foy M, Keener G, Amos CI, Spitz MR, Kimmel M, Gorlova OYLung cancer (Amsterdam, Netherlands)Association of smoking with tumor size at diagnosis in non-small cell lung cancer. Lung Cancer. 2011 Dec; 74(3):378-83.Lung Cancer2011-06-08T00:00:002011Association of smoking with tumor size at diagnosis in non-small cell lung cancer.21771723Pande M, Spitz MR, Wu X, Gorlov IP, Chen WV, Amos CICarcinogenesisNovel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk. Carcinogenesis. 2011 Oct; 32(10):1493-9.Carcinogenesis2011-07-18T00:00:002011Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk.17804757Gorlov IP, Meyer P, Liloglou T, Myles J, Boettger MB, Cassidy A, Girard L, Minna JD, Fischer R, Duffy S, Spitz MR, Haeussinger K, Kammerer S, Cantor C, Dierkesmann R, Field JK, Amos CICancer researchSeizure 6-like (SEZ6L) gene and risk for lung cancer. Cancer Res. 2007 Sep 01; 67(17):8406-11.Cancer Res2007-09-01T00:00:002007Seizure 6-like (SEZ6L) gene and risk for lung cancer.22586632Spitz MR, Gorlov IP, Amos CI, Dong Q, Chen W, Etzel CJ, Gorlova OY, Chang DW, Pu X, Zhang D, Wang L, Cunningham JM, Yang P, Wu XCancer discoveryVariants in inflammation genes are implicated in risk of lung cancer in never smokers exposed to second-hand smoke. Cancer Discov. 2011 Oct; 1(5):420-9.Cancer Discov2011-08-25T00:00:002011Variants in inflammation genes are implicated in risk of lung cancer in never smokers exposed to second-hand smoke.22809343Gorlova OY, Ying J, Amos CI, Spitz MR, Peng B, Gorlov IPJournal of bioinformatics and computational biologyDerived SNP alleles are used more frequently than ancestral alleles as risk-associated variants in common human diseases. J Bioinform Comput Biol. 2012 Apr; 10(2):1241008.J Bioinform Comput Biol2012-04-01T00:00:002012Derived SNP alleles are used more frequently than ancestral alleles as risk-associated variants in common human diseases.23221128Walsh KM, Gorlov IP, Hansen HM, Wu X, Spitz MR, Zhang H, Lu EY, Wenzlaff AS, Sison JD, Wei C, Lloyd SM, Chen W, Frazier ML, Seldin MF, Bierut LJ, Bracci PM, Wrensch MR, Schwartz AG, Wiencke JK, Amos CICancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive OncologyFine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. Cancer Epidemiol Biomarkers Prev. 2013 Feb; 22(2):251-60.Cancer Epidemiol Biomarkers Prev2012-12-05T00:00:002012Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans.22322597Kaftanovskaya EM, Huang Z, Barbara AM, De Gendt K, Verhoeven G, Gorlov IP, Agoulnik AIMolecular endocrinology (Baltimore, Md.)Cryptorchidism in mice with an androgen receptor ablation in gubernaculum testis. Mol Endocrinol. 2012 Apr; 26(4):598-607.Mol Endocrinol2012-02-09T00:00:002012Cryptorchidism in mice with an androgen receptor ablation in gubernaculum testis.22573796Spitz MR, Gorlov IP, Dong Q, Wu X, Chen W, Chang DW, Etzel CJ, Caporaso NE, Zhao Y, Christiani DC, Brennan P, Albanes D, Shi J, Thun M, Landi MT, Amos CICancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive OncologyMultistage analysis of variants in the inflammation pathway and lung cancer risk in smokers. Cancer Epidemiol Biomarkers Prev. 2012 Jul; 21(7):1213-21.Cancer Epidemiol Biomarkers Prev2012-05-09T00:00:002012Multistage analysis of variants in the inflammation pathway and lung cancer risk in smokers.15117811Lin J, Spitz MR, Wang Y, Schabath MB, Gorlov IP, Hernandez LM, Pillow PC, Grossman HB, Wu XCarcinogenesisPolymorphisms of folate metabolic genes and susceptibility to bladder cancer: a case-control study. Carcinogenesis. 2004 Sep; 25(9):1639-47.Carcinogenesis2004-04-29T00:00:002004Polymorphisms of folate metabolic genes and susceptibility to bladder cancer: a case-control study.17582598Yang H, Spitz MR, Stewart DJ, Lu C, Gorlov IP, Wu XInternational journal of cancerATM sequence variants associate with susceptibility to non-small cell lung cancer. Int J Cancer. 2007 Nov 15; 121(10):2254-9.Int J Cancer2007-11-15T00:00:002007ATM sequence variants associate with susceptibility to non-small cell lung cancer.20554942Amos CI, Gorlov IP, Dong Q, Wu X, Zhang H, Lu EY, Scheet P, Greisinger AJ, Mills GB, Spitz MRJournal of the National Cancer InstituteNicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study. J Natl Cancer Inst. 2010 Aug 04; 102(15):1199-205.J Natl Cancer Inst2010-06-16T00:00:002010Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study.21147849Kaftanovskaya EM, Feng S, Huang Z, Tan Y, Barbara AM, Kaur S, Truong A, Gorlov IP, Agoulnik AIMolecular endocrinology (Baltimore, Md.)Suppression of insulin-like3 receptor reveals the role of ?-catenin and Notch signaling in gubernaculum development. Mol Endocrinol. 2011 Jan; 25(1):170-83.Mol Endocrinol2010-12-08T00:00:002010Suppression of insulin-like3 receptor reveals the role of ?-catenin and Notch signaling in gubernaculum development.23232035Walsh KM, Amos CI, Wenzlaff AS, Gorlov IP, Sison JD, Wu X, Spitz MR, Hansen HM, Lu EY, Wei C, Zhang H, Chen W, Lloyd SM, Frazier ML, Bracci PM, Seldin MF, Wrensch MR, Schwartz AG, Wiencke JKOncotargetAssociation study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans. Oncotarget. 2012 Nov; 3(11):1428-38.Oncotarget2012-11-01T00:00:002012Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans.14526391Gorlov IP, Gorlova OY, Frazier ML, Amos CIAmerican journal of human geneticsMissense mutations in hMLH1 and hMSH2 are associated with exonic splicing enhancers. Am J Hum Genet. 2003 Nov; 73(5):1157-61.Am J Hum Genet2003-10-01T00:00:002003Missense mutations in hMLH1 and hMSH2 are associated with exonic splicing enhancers.15450416Gorlov IP, Gorlova OY, Frazier ML, Amos CIMutation researchMissense mutations in cancer suppressor gene TP53 are colocalized with exonic splicing enhancers (ESEs). Mutat Res. 2004 Oct 04; 554(1-2):175-83.Mutat Res2004-10-04T00:00:002004Missense mutations in cancer suppressor gene TP53 are colocalized with exonic splicing enhancers (ESEs).16173033Gorlov IP, Gorlova OY, Amos CIHuman mutationPredicting the oncogenicity of missense mutations reported in the International Agency for Cancer Research (IARC) mutation database on p53. Hum Mutat. 2005 Nov; 26(5):446-54.Hum Mutat2005-11-01T00:00:002005Predicting the oncogenicity of missense mutations reported in the International Agency for Cancer Research (IARC) mutation database on p53.16500998Gorlov IP, Kimmel M, Amos CIHuman molecular geneticsStrength of the purifying selection against different categories of the point mutations in the coding regions of the human genome. Hum Mol Genet. 2006 Apr 01; 15(7):1143-50.Hum Mol Genet2006-02-24T00:00:002006Strength of the purifying selection against different categories of the point mutations in the coding regions of the human genome.18559102Gorlov IP, Gorlova OY, Amos CIBMC genomicsRelative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome. BMC Genomics. 2008 Jun 17; 9:292.BMC Genomics2008-06-17T00:00:002008Relative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome.25273843Gorlov IP, Moore JH, Peng B, Jin JL, Gorlova OY, Amos CIHuman geneticsSNP characteristics predict replication success in association studies. Hum Genet. 2014 Dec; 133(12):1477-86.Hum Genet2014-10-02T00:00:002014SNP characteristics predict replication success in association studies.26576671Halloran JW, Zhu D, Qian DC, Byun J, Gorlova OY, Amos CI, Gorlov IPBMC medical genomicsPrediction of the gene expression in normal lung tissue by the gene expression in blood. BMC Med Genomics. 2015 Nov 17; 8:77.BMC Med Genomics2015-11-17T00:00:002015Prediction of the gene expression in normal lung tissue by the gene expression in blood.26201053Gorlov IP, Gorlova OY, Amos CIPLoS geneticsAllelic Spectra of Risk SNPs Are Different for Environment/Lifestyle Dependent versus Independent Diseases. PLoS Genet. 2015 Jul; 11(7):e1005371.PLoS Genet2015-07-22T00:00:002015Allelic Spectra of Risk SNPs Are Different for Environment/Lifestyle Dependent versus Independent Diseases.26961892Li Y, Byun J, Cai G, Xiao X, Han Y, Cornelis O, Dinulos JE, Dennis J, Easton D, Gorlov I, Seldin MF, Amos CIBMC bioinformaticsFastPop: a rapid principal component derived method to infer intercontinental ancestry using genetic data. BMC Bioinformatics. 2016 Mar 09; 17:122.BMC Bioinformatics2016-03-09T00:00:002016FastPop: a rapid principal component derived method to infer intercontinental ancestry using genetic data.28334950Gorlova OY, Demidenko EI, Amos CI, Gorlov IPHuman molecular geneticsDownstream targets of GWAS-detected genes for breast, lung, and prostate and colon cancer converge to G1/S transition pathway. Hum Mol Genet. 2017 04 15; 26(8):1465-1471.Hum Mol Genet2017-04-15T00:00:002017Downstream targets of GWAS-detected genes for breast, lung, and prostate and colon cancer converge to G1/S transition pathway.29293537Gorlova OY, Li Y, Gorlov I, Ying J, Chen WV, Assassi S, Reveille JD, Arnett FC, Zhou X, Bossini-Castillo L, Lopez-Isac E, Acosta-Herrera M, Gregersen PK, Lee AT, Steen VD, Fessler BJ, Khanna D, Schiopu E, Silver RM, Molitor JA, Furst DE, Kafaja S, Simms RW, Lafyatis RA, Carreira P, Simeon CP, Castellvi I, Beltran E, Ortego N, Amos CI, Martin J, Mayes MDPloS oneGene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. PLoS One. 2018; 13(1):e0189498.PLoS One2018-01-02T00:00:002018Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations.29037167Byun J, Han Y, Gorlov IP, Busam JA, Seldin MF, Amos CIBMC genomicsAncestry inference using principal component analysis and spatial analysis: a distance-based analysis to account for population substructure. BMC Genomics. 2017 Oct 16; 18(1):789.BMC Genomics2017-10-16T00:00:002017Ancestry inference using principal component analysis and spatial analysis: a distance-based analysis to account for population substructure.CHRISAMOSCHRIS AMOS13498AMOS, CHRISProfessortrue1ProfessorProfessortrue1ProfessorProfessorD015894Genes & Molecular Sequences51818690.530545Genome, HumanD020641Genes & Molecular Sequences78245430.418481Polymorphism, Single NucleotideD018389Chemicals & DrugsPhysiology1031640.92158Codon, NonsenseD055106Procedures47722630.533612Genome-Wide Association StudyD020022Physiology114455400.372407Genetic Predisposition to Disease29856256Ji X, Niu X, Qian J, Martucci V, Pendergrass SA, Gorlov IP, Amos CI, Denny JC, Massion PP, Aldrich MCAmerican journal of respiratory cell and molecular biologyA Phenome-Wide Association Study Uncovers a Role for Autoimmunity in the Development of Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2018 06; 58(6):777-779.Am J Respir Cell Mol Biol2018-06-01T00:00:002018A Phenome-Wide Association Study Uncovers a Role for Autoimmunity in the Development of Chronic Obstructive Pulmonary Disease.29975213Gorlov I, Orlow I, Ringelberg C, Hernando E, Ernstoff MS, Cheng C, Her S, Parker JS, Thompson CL, Gerstenblith MR, Berwick M, Amos CMelanoma researchIdentification of gene expression levels in primary melanoma associated with clinically meaningful characteristics. Melanoma Res. 2018 10; 28(5):380-389.Melanoma Res2018-10-01T00:00:002018Identification of gene expression levels in primary melanoma associated with clinically meaningful characteristics.30104567Ji X, Boss? Y, Landi MT, Gui J, Xiao X, Qian D, Joubert P, Lamontagne M, Li Y, Gorlov I, de Biasi M, Han Y, Gorlova O, Hung RJ, Wu X, McKay J, Zong X, Carreras-Torres R, Christiani DC, Caporaso N, Johansson M, Liu G, Bojesen SE, Le Marchand L, Albanes D, Bickeb?ller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Chen C, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Shen H, Hong YC, Yuan JM, Bertazzi PA, Pesatori AC, Ye Y, Diao N, Su L, Zhang R, Brhane Y, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman C, Wilkens L, Fernandez-Somoano A, Fernandez-Tardon G, van der Heijden EHFM, Kim JH, Dai J, Hu Z, Davies MPA, Marcus MW, Brunnstr?m H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Doherty J, Goodman GE, Cox A, Taylor F, Woll P, Br?ske I, Manz J, Muley T, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd F, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Koh WP, Gao YT, Houlston R, McLaughlin J, Stevens V, Nickle DC, Obeidat M, Timens W, Zhu B, Song L, Artigas MS, Tobin MD, Wain LV, Gu F, Byun J, Kamal A, Zhu D, Tyndale RF, Wei WQ, Chanock S, Brennan P, Amos CINature communicationsIdentification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk. Nat Commun. 2018 08 13; 9(1):3221.Nat Commun2018-08-13T00:00:002018Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk.30171176Zhao Y, Schaafsma E, Gorlov IP, Hernando E, Thomas NE, Shen R, Turk MJ, Berwick M, Amos CI, Cheng CMolecular cancer research : MCRA Leukocyte Infiltration Score Defined by a Gene Signature Predicts Melanoma Patient Prognosis. Mol Cancer Res. 2019 01; 17(1):109-119.Mol Cancer Res2018-08-31T00:00:002018A Leukocyte Infiltration Score Defined by a Gene Signature Predicts Melanoma Patient Prognosis.30453881Gorlov IP, Pikielny CW, Frost HR, Her SC, Cole MD, Strohbehn SD, Wallace-Bradley D, Kimmel M, Gorlova OY, Amos CIBMC bioinformaticsGene characteristics predicting missense, nonsense and frameshift mutations in tumor samples. BMC Bioinformatics. 2018 Nov 19; 19(1):430.BMC Bioinformatics2018-11-19T00:00:002018Gene characteristics predicting missense, nonsense and frameshift mutations in tumor samples.Department of MedicineDepartment of Molecular & Human GeneticsMedicine-Athero & LipoproteinsMolecular & Human GeneticsBaylor College of MedicineMARGARETSPITZMARGARET SPITZ0.000000000000000.000000000000001692SPITZ, MARGARETProfessor EmeritusERICBOERWINKLEERIC BOERWINKLE0.000000000000000.000000000000002653BOERWINKLE, ERICAdjunct ProfessorJAMESLUPSKIJAMES LUPSKI29.71073630000000-95.396604500000003140LUPSKI, JAMESProfessor30803560Gorlov IP, Gorlova OY, Amos CICancer geneticsUntouchable genes in the human genome: Identifying ideal targets for cancer treatment. Cancer Genet. 2019 02; 231-232:67-79.Cancer Genet2019-01-24T00:00:002019Untouchable genes in the human genome: Identifying ideal targets for cancer treatment.RICHARDGIBBSRICHARD GIBBS0.000000000000000.000000000000003131GIBBS, RICHARDDistinguished Service Professor30956756Li Y, Xiao X, Boss? Y, Gorlova O, Gorlov I, Han Y, Byun J, Leighl N, Johansen JS, Barnett M, Chen C, Goodman G, Cox A, Taylor F, Woll P, Wichmann HE, Manz J, Muley T, Risch A, Rosenberger A, Han J, Siminovitch K, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Houlston R, Artigas MS, Grankvist K, Johansson M, Shepherd FA, Marcus MW, Brunnstr?m H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Liu G, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeb?ller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Bertazzi PA, Pesatori AC, Christiani DC, Caporaso N, Johansson M, McKay JD, Brennan P, Hung RJ, Amos CIOncotargetGenetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development. Oncotarget. 2019 Mar 05; 10(19):1760-1774.Oncotarget2019-03-05T00:00:002019Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development.31009812Hung RJ, Spitz MR, Houlston RS, Schwartz AG, Field JK, Ying J, Li Y, Han Y, Ji X, Chen W, Wu X, Gorlov IP, Na J, de Andrade M, Liu G, Brhane Y, Diao N, Wenzlaff A, Davies MPA, Liloglou T, Timofeeva M, Muley T, Rennert H, Saliba W, Ryan BM, Bowman E, Barros-Dios JM, P?rez-R?os M, Morgenstern H, Zienolddiny S, Skaug V, Ugolini D, Bonassi S, van der Heijden EHFM, Tardon A, Bojesen SE, Landi MT, Johansson M, Bickeb?ller H, Arnold S, Le Marchand L, Melander O, Andrew A, Grankvist K, Caporaso N, Teare MD, Schabath MB, Aldrich MC, Kiemeney LA, Wichmann HE, Lazarus P, Mayordomo J, Neri M, Haugen A, Zhang ZF, Ruano-Ravi?a A, Brenner H, Harris CC, Orlow I, Rennert G, Risch A, Brennan P, Christiani DC, Amos CI, Yang P, Gorlova OYJournal of thoracic oncology : official publication of the International Association for the Study of Lung CancerLung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region. J Thorac Oncol. 2019 08; 14(8):1360-1369.J Thorac Oncol2019-04-19T00:00:002019Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region.true1Assistant ProfessorAssistant ProfessorJINYOUNGBYUNJINYOUNG BYUN14807BYUN, JINYOUNGAssistant ProfessorOLGAGORLOVAOLGA GORLOVA15184GORLOVA, OLGAAssociate Professor31718536Gorlov I, Xiao X, Mayes M, Gorlova O, Amos CBMC geneticsSNP eQTL status and eQTL density in the adjacent region of the SNP are associated with its statistical significance in GWA studies. BMC Genet. 2019 11 12; 20(1):85.BMC Genet2019-11-12T00:00:002019SNP eQTL status and eQTL density in the adjacent region of the SNP are associated with its statistical significance in GWA studies.3.019170.0078971259research areas12.35530.020636941coauthor of176.74416.347960similar to1172selected publications2019-07-31NIH/NLMGORLOV, IVAN P2017-08-01Predicting SNP priors for Cancer GWASsR56LM0123712010-08-31NIH/NCIGORLOV, IVAN P2007-09-24The Odd-Even Effect of Polymorphic CA repeats in the 5' Regulatory Region of theR03CA1280252011-08-31NIH/NCIGORLOV, IVAN P2008-09-26Tobacco Smoke Sensitive Genes and Genetic Susceptibility to Small-Cell Lung CanceR03CA133885Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorAuthorship 9652671Authorship 9656141Authorship 9669091Authorship 9672561Authorship 9674355Authorship 9674661Authorship 9681991Authorship 9682281Authorship 9687075Authorship 9688134Authorship 9689171Authorship 9689181Authorship 9690641Authorship 9691623Authorship 9693902Authorship 9695444Authorship 9695691Authorship 9697452Authorship 9698594Authorship 9699126Authorship 9699938Authorship 9703903Authorship 9704182Authorship 9704842Authorship 9704914Authorship 9706322Authorship 9706392Authorship 9706411Authorship 9706871Authorship 9708716Authorship 9708721Authorship 9709099Authorship 9711205Authorship 9711391Authorship 9717461Authorship 9721581Authorship 9721632Authorship 9722647Authorship 9726764Authorship 97284710Authorship 97289616Authorship 9730803Authorship 9734461Authorship 9734523Authorship 9735021Authorship 9735533Authorship 9736286Authorship 9736447Authorship 9737444Authorship 9738333Authorship 9742081Authorship 97426112Authorship 974308127263110Dagrosa LM, Ingimarsson JP, Gorlov IP, Higgins JH, Hyams ESJournal of robotic surgeryIs age an independent risk factor for medical complications following minimally invasive radical prostatectomy? An evaluation of contemporary American College of Surgeons National Surgical Quality Improvement (ACS-NSQIP) data. J Robot Surg. 2016 Dec; 10(4):343-346.J Robot Surg2016-06-04T00:00:002016Is age an independent risk factor for medical complications following minimally invasive radical prostatectomy? An evaluation of contemporary American College of Surgeons National Surgical Quality Improvement (ACS-NSQIP) data.26205736Tafe LJ, Gorlov IP, de Abreu FB, Lefferts JA, Liu X, Pettus JR, Marotti JD, Bloch KJ, Memoli VA, Suriawinata AA, Dragnev KH, Fadul CE, Schwartz GN, Morgan CR, Holderness BM, Peterson JD, Tsongalis GJ, Miller TW, Chamberlin MDThe oncologistImplementation of a Molecular Tumor Board: The Impact on Treatment Decisions for 35 Patients Evaluated at Dartmouth-Hitchcock Medical Center. Oncologist. 2015 Sep; 20(9):1011-8.Oncologist2015-07-23T00:00:002015Implementation of a Molecular Tumor Board: The Impact on Treatment Decisions for 35 Patients Evaluated at Dartmouth-Hitchcock Medical Center.true1Adjunct ProfessorAdjunct ProfessorAuthorship 986863332277007Wang Y, Gorlova OY, Gorlov IP, Zhu M, Dai J, Albanes D, Lam S, Tardon A, Chen C, Goodman GE, Bojesen SE, Landi MT, Johansson M, Risch A, Wichmann HE, Bickeboller H, Christiani DC, Rennert G, Arnold SM, Brennan P, Field JK, Shete S, Le Marchand L, Melander O, Brunnstrom H, Liu G, Hung RJ, Andrew AS, Kiemeney LA, Zienolddiny S, Grankvist K, Johansson M, Caporaso NE, Woll PJ, Lazarus P, Schabath MB, Aldrich MC, Stevens VL, Ma H, Jin G, Hu Z, Amos CI, Shen HCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive OncologyAssociation Analysis of Driver Gene-Related Genetic Variants Identified Novel Lung Cancer Susceptibility Loci with 20,871 Lung Cancer Cases and 15,971 Controls. Cancer Epidemiol Biomarkers Prev. 2020 07; 29(7):1423-1429.Cancer Epidemiol Biomarkers Prev2020-04-10T00:00:002020Association Analysis of Driver Gene-Related Genetic Variants Identified Novel Lung Cancer Susceptibility Loci with 20,871 Lung Cancer Cases and 15,971 Controls.Authorship 989283532393777Ji X, Mukherjee S, Landi MT, Bosse Y, Joubert P, Zhu D, Gorlov I, Xiao X, Han Y, Gorlova O, Hung RJ, Brhane Y, Carreras-Torres R, Christiani DC, Caporaso N, Johansson M, Liu G, Bojesen SE, Le Marchand L, Albanes D, Bickeb?ller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Chen C, Byun J, Dragnev KH, Field JK, Kiemeney LF, Lazarus P, Zienolddiny S, Lam S, Schabath MB, Andrew AS, Bertazzi PA, Pesatori AC, Diao N, Su L, Song L, Zhang R, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman C, Wilkens L, Fernandez-Somoano A, Fernandez-Tardon G, Heijden EHFMV, Kim JH, Davies MPA, Marcus MW, Brunnstr?m H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Goodman GE, Cox A, Taylor F, Woll P, Wichmann E, Muley T, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd F, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Butler LM, Offit K, Srinivasan P, Bandlamudi C, Hellmann MD, Solit DB, Robson ME, Rudin CM, Stadler ZK, Taylor BS, Berger MF, Houlston R, McLaughlin J, Stevens V, Nickle DC, Obeidat M, Timens W, Artigas MS, Shete S, Brenner H, Chanock S, Brennan P, McKay JD, Amos CINature communicationsProtein-altering germline mutations implicate novel genes related to lung cancer development. Nat Commun. 2020 05 11; 11(1):2220.Nat Commun2020-05-11T00:00:002020Protein-altering germline mutations implicate novel genes related to lung cancer development.Authorship 993137332613070Bernhardt EB, Chamberlin MD, Gorlov IP, de Abreu FB, Bloch KJ, Peterson JD, Tsongalis GJ, Shirai K, Dragnev KH, Miller TW, Tafe LJPractical laboratory medicineMolecular matching and treatment strategies for advanced stage lung cancer at Dartmouth-Hitchcock Medical Center: A three-year review of a Molecular Tumor Board. Pract Lab Med. 2020 Aug; 21:e00174.Pract Lab Med2020-06-12T00:00:002020Molecular matching and treatment strategies for advanced stage lung cancer at Dartmouth-Hitchcock Medical Center: A three-year review of a Molecular Tumor Board.Authorship 993907132643855Gorlov IP, Amos CI, Tsavachidis S, Begg C, Hernando E, Cheng C, Shen R, Orlow I, Luo L, Ernstoff MS, Parker J, Thomas NE, Gorlova OY, Berwick MHuman mutationHuman genes differ by their UV sensitivity estimated through analysis of UV-induced silent mutations in melanoma. Hum Mutat. 2020 10; 41(10):1751-1760.Hum Mutat2020-07-15T00:00:002020Human genes differ by their UV sensitivity estimated through analysis of UV-induced silent mutations in melanoma.Authorship 994633132681635Gorlov IP, Xia X, Tsavachidis S, Gorlova OY, Amos CICarcinogenesisTumor somatic mutations also existing as germline polymorphisms may help to identify functional SNPs from genome-wide association studies. Carcinogenesis. 2020 10 15; 41(10):1353-1362.Carcinogenesis2020-10-15T00:00:002020Tumor somatic mutations also existing as germline polymorphisms may help to identify functional SNPs from genome-wide association studies.Authorship 996871432785663Jia X, Sun C, Tang O, Gorlov I, Nambi V, Virani SS, Villareal DT, Taffet GE, Yu B, Bressler J, Boerwinkle E, Windham BG, de Lemos JA, Matsushita K, Selvin E, Michos ED, Hoogeveen RC, Ballantyne CMThe Journal of clinical endocrinology and metabolismPlasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women. J Clin Endocrinol Metab. 2020 12 01; 105(12).J Clin Endocrinol Metab2020-12-01T00:00:002020Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women.true1Associate ProfessorAssociate Professortrue1Distinguished Service ProfessorDistinguished Service ProfessorAuthorship 1036516534981173Gorlova OY, Xiao X, Tsavachidis S, Amos CI, Gorlov IPHuman geneticsSNP characteristics and validation success in genome wide association studies. Hum Genet. 2022 Feb; 141(2):229-238.Hum Genet2022-01-04T00:00:002022SNP characteristics and validation success in genome wide association studies.Authorship 10396473935138370Li Y, Xiao X, Li J, Byun J, Cheng C, Boss? Y, McKay J, Albanes D, Lam S, Tardon A, Chen C, Bojesen SE, Landi MT, Johansson M, Risch A, Bickeb?ller H, Wichmann HE, Christiani DC, Rennert G, Arnold S, Goodman G, Field JK, Davies MPA, Shete SS, Le Marchand L, Melander O, Brunnstr?m H, Liu G, Hung RJ, Andrew AS, Kiemeney LA, Shen H, Sun R, Zienolddiny S, Grankvist K, Johansson M, Caporaso N, Teare DM, Hong YC, Lazarus P, Schabath MB, Aldrich MC, Schwartz AG, Gorlov I, Purrington K, Yang P, Liu Y, Han Y, Bailey-Wilson JE, Pinney SM, Mandal D, Willey JC, Gaba C, Brennan P, Amos CI, INTEGRAL-ILCCO lung cancer consortiumHuman molecular geneticsGenome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk. Hum Mol Genet. 2022 08 23; 31(16):2831-2843.Hum Mol Genet2022-08-23T00:00:002022Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk.true1Associate ProfessorAssociate Professor23125224Chen J, Pande M, Huang YJ, Wei C, Amos CI, Talseth-Palmer BA, Meldrum CJ, Chen WV, Gorlov IP, Lynch PM, Scott RJ, Frazier MLCarcinogenesisCell cycle-related genes as modifiers of age of onset of colorectal cancer in Lynch syndrome: a large-scale study in non-Hispanic white patients. Carcinogenesis. 2013 Feb; 34(2):299-306.Carcinogenesis2012-11-03T00:00:002012Cell cycle-related genes as modifiers of age of onset of colorectal cancer in Lynch syndrome: a large-scale study in non-Hispanic white patients.Authorship 1046857535634240Gorlova OY, Kimmel M, Tsavachidis S, Amos CI, Gorlov IPOncotargetIdentification of lung cancer drivers by comparison of the observed and the expected numbers of missense and nonsense mutations in individual human genes. Oncotarget. 2022; 13:756-767.Oncotarget2022-05-25T00:00:002022Identification of lung cancer drivers by comparison of the observed and the expected numbers of missense and nonsense mutations in individual human genes.35876628Luo L, Shen R, Arora A, Orlow I, Busam KJ, Lezcano C, Lee TK, Hernando E, Gorlov I, Amos C, Ernstoff MS, Seshan VE, Cust AE, Wilmott J, Scolyer RA, Mann G, Nagore E, Funchain P, Ko J, Ngo P, Edmiston SN, Conway K, Googe PB, Ollila D, Lee JE, Fang S, Rees JR, Thompson CL, Gerstenblith M, Bosenberg M, Gould Rothberg B, Osman I, Saenger Y, Reynolds AZ, Schwartz M, Boyce T, Holmen S, Brunsgaard E, Bogner P, Kuan PF, Wiggins C, Thomas NE, Begg CB, Berwick M, InterMELPigment cell & melanoma researchLandscape of mutations in early stage primary cutaneous melanoma: An InterMEL study. Pigment Cell Melanoma Res. 2022 11; 35(6):605-612.Pigment Cell Melanoma Res2022-08-12T00:00:002022Landscape of mutations in early stage primary cutaneous melanoma: An InterMEL study.Authorship 106029424Authorship 1061417935915169Byun J, Han Y, Li Y, Xia J, Long E, Choi J, Xiao X, Zhu M, Zhou W, Sun R, Boss? Y, Song Z, Schwartz A, Lusk C, Rafnar T, Stefansson K, Zhang T, Zhao W, Pettit RW, Liu Y, Li X, Zhou H, Walsh KM, Gorlov I, Gorlova O, Zhu D, Rosenberg SM, Pinney S, Bailey-Wilson JE, Mandal D, de Andrade M, Gaba C, Willey JC, You M, Anderson M, Wiencke JK, Albanes D, Lam S, Tardon A, Chen C, Goodman G, Bojeson S, Brenner H, Landi MT, Chanock SJ, Johansson M, Muley T, Risch A, Wichmann HE, Bickeb?ller H, Christiani DC, Rennert G, Arnold S, Field JK, Shete S, Le Marchand L, Melander O, Brunnstrom H, Liu G, Andrew AS, Kiemeney LA, Shen H, Zienolddiny S, Grankvist K, Johansson M, Caporaso N, Cox A, Hong YC, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Patel A, Lan Q, Rothman N, Taylor F, Kachuri L, Witte JS, Sakoda LC, Spitz M, Brennan P, Lin X, McKay J, Hung RJ, Amos CINature geneticsCross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer. Nat Genet. 2022 08; 54(8):1167-1177.Nat Genet2022-08-01T00:00:002022Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer.Authorship 1064304136805567Gorlov IP, Conway K, Edmiston SN, Parrish EA, Hao H, Amos CI, Tsavachidis S, Gorlova OY, Begg C, Hernando E, Cheng C, Shen R, Orlow I, Luo L, Ernstoff MS, Kuan PF, Ollila DW, Tsai YS, Berwick M, Thomas NEMelanoma researchMethylation of nonessential genes in cutaneous melanoma - Rule Out hypothesis. Melanoma Res. 2023 06 01; 33(3):163-172.Melanoma Res2023-02-20T00:00:002023Methylation of nonessential genes in cutaneous melanoma - Rule Out hypothesis.Authorship 1064881136848382Gorlov IP, Amos CIPLoS geneticsWhy does the X chromosome lag behind autosomes in GWAS findings? PLoS Genet. 2023 02; 19(2):e1010472.PLoS Genet2023-02-27T00:00:002023Why does the X chromosome lag behind autosomes in GWAS findings?Authorship 10701597Authorship 10708234537150255Cheng C, Hong W, Li Y, Xiao X, McKay J, Han Y, Byun J, Peng B, Albanes D, Lam S, Tardon A, Chen C, Bojesen SE, Landi MT, Johansson M, Risch A, Bickeb?ller H, Wichmann HE, Christiani DC, Rennert G, Arnold S, Goodman G, Field JK, Davies MPA, Shete SS, Le Marchand L, Liu G, Hung RJ, Andrew AS, Kiemeney LA, Zhu M, Shen H, Zienolddiny S, Grankvist K, Johansson M, Cox A, Hong YC, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Brennan P, Li Y, Gorlova O, Gorlov I, Amos CI, INTEGRAL-ILCCO Lung Cancer ConsortiumJournal of thoracic oncology : official publication of the International Association for the Study of Lung CancerMosaic Chromosomal Alterations Are Associated With Increased Lung Cancer Risk: Insight From the INTEGRAL-ILCCO Cohort Analysis. J Thorac Oncol. 2023 08; 18(8):1003-1016.J Thorac Oncol2023-05-05T00:00:002023Mosaic Chromosomal Alterations Are Associated With Increased Lung Cancer Risk: Insight From the INTEGRAL-ILCCO Cohort Analysis.37146750Cheng C, Nguyen TT, Tang M, Wang X, Jiang C, Liu Y, Gorlov I, Gorlova O, Iafrate J, Lanuti M, Christiani DC, Amos CIJournal of thoracic oncology : official publication of the International Association for the Study of Lung CancerImmune Infiltration in Tumor and Adjacent Non-Neoplastic Regions Codetermines Patient Clinical Outcomes in Early-Stage Lung Cancer. J Thorac Oncol. 2023 09; 18(9):1184-1198.J Thorac Oncol2023-05-04T00:00:002023Immune Infiltration in Tumor and Adjacent Non-Neoplastic Regions Codetermines Patient Clinical Outcomes in Early-Stage Lung Cancer.Authorship 107231111037236969Shi J, Shiraishi K, Choi J, Matsuo K, Chen TY, Dai J, Hung RJ, Chen K, Shu XO, Kim YT, Landi MT, Lin D, Zheng W, Yin Z, Zhou B, Song B, Wang J, Seow WJ, Song L, Chang IS, Hu W, Chien LH, Cai Q, Hong YC, Kim HN, Wu YL, Wong MP, Richardson BD, Funderburk KM, Li S, Zhang T, Breeze C, Wang Z, Blechter B, Bassig BA, Kim JH, Albanes D, Wong JYY, Shin MH, Chung LP, Yang Y, An SJ, Zheng H, Yatabe Y, Zhang XC, Kim YC, Caporaso NE, Chang J, Ho JCM, Kubo M, Daigo Y, Song M, Momozawa Y, Kamatani Y, Kobayashi M, Okubo K, Honda T, Hosgood DH, Kunitoh H, Patel H, Watanabe SI, Miyagi Y, Nakayama H, Matsumoto S, Horinouchi H, Tsuboi M, Hamamoto R, Goto K, Ohe Y, Takahashi A, Goto A, Minamiya Y, Hara M, Nishida Y, Takeuchi K, Wakai K, Matsuda K, Murakami Y, Shimizu K, Suzuki H, Saito M, Ohtaki Y, Tanaka K, Wu T, Wei F, Dai H, Machiela MJ, Su J, Kim YH, Oh IJ, Lee VHF, Chang GC, Tsai YH, Chen KY, Huang MS, Su WC, Chen YM, Seow A, Park JY, Kweon SS, Chen KC, Gao YT, Qian B, Wu C, Lu D, Liu J, Schwartz AG, Houlston R, Spitz MR, Gorlov IP, Wu X, Yang P, Lam S, Tardon A, Chen C, Bojesen SE, Johansson M, Risch A, Bickeb?ller H, Ji BT, Wichmann HE, Christiani DC, Rennert G, Arnold S, Brennan P, McKay J, Field JK, Shete SS, Le Marchand L, Liu G, Andrew A, Kiemeney LA, Zienolddiny-Narui S, Grankvist K, Johansson M, Cox A, Taylor F, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Jeon HS, Jiang SS, Sung JS, Chen CH, Hsiao CF, Jung YJ, Guo H, Hu Z, Burdett L, Yeager M, Hutchinson A, Hicks B, Liu J, Zhu B, Berndt SI, Wu W, Wang J, Li Y, Choi JE, Park KH, Sung SW, Liu L, Kang CH, Wang WC, Xu J, Guan P, Tan W, Yu CJ, Yang G, Sihoe ADL, Chen Y, Choi YY, Kim JS, Yoon HI, Park IK, Xu P, He Q, Wang CL, Hung HH, Vermeulen RCH, Cheng I, Wu J, Lim WY, Tsai FY, Chan JKC, Li J, Chen H, Lin HC, Jin L, Liu J, Sawada N, Yamaji T, Wyatt K, Li SA, Ma H, Zhu M, Wang Z, Cheng S, Li X, Ren Y, Chao A, Iwasaki M, Zhu J, Jiang G, Fei K, Wu G, Chen CY, Chen CJ, Yang PC, Yu J, Stevens VL, Fraumeni JF, Chatterjee N, Gorlova OY, Hsiung CA, Amos CI, Shen H, Chanock SJ, Rothman N, Kohno T, Lan QNature communicationsGenome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population. Nat Commun. 2023 05 26; 14(1):3043.Nat Commun2023-05-26T00:00:002023Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population.Authorship 10846301038055287Zhao X, Yang M, Fan J, Wang M, Wang Y, Qin N, Zhu M, Jiang Y, Gorlova OY, Gorlov IP, Albanes D, Lam S, Tard?n A, Chen C, Goodman GE, Bojesen SE, Landi MT, Johansson M, Risch A, Wichmann HE, Bickeb?ller H, Christiani DC, Rennert G, Arnold SM, Brennan P, Field JK, Shete S, Le Marchand L, Liu G, Hung RJ, Andrew AS, Kiemeney LA, Zienolddiny S, Grankvist K, Johansson M, Caporaso NE, Woll PJ, Lazarus P, Schabath MB, Aldrich MC, Patel AV, Davies MPA, Ma H, Jin G, Hu Z, Amos CI, Shen H, Dai JCancerIdentification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls. Cancer. 2024 03 15; 130(6):913-926.Cancer2023-12-06T00:00:002023Identification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls.Authorship 1084895836926987Kostrzewa CE, Luo L, Arora A, Seshan VE, Ernstoff MS, Edmiston SN, Conway K, Gorlov I, Busam K, Orlow I, Hernando-Monge E, Thomas NE, Berwick M, Begg CB, Shen R, for InterMELJCO precision oncologyPathway Alterations in Stage II/III Primary Melanoma. JCO Precis Oncol. 2023 03; 7:e2200439.JCO Precis Oncol2023-03-01T00:00:002023Pathway Alterations in Stage II/III Primary Melanoma.Authorship 10862624638180474Li Y, Xiao X, Li J, Han Y, Cheng C, Fernandes GF, Slewitzke SE, Rosenberg SM, Zhu M, Byun J, Boss? Y, McKay JD, Albanes D, Lam S, Tardon A, Chen C, Bojesen SE, Landi MT, Johansson M, Risch A, Bickeb?ller H, Wichmann HE, Christiani DC, Rennert G, Arnold SM, Goodman GE, Field JK, Davies MPA, Shete S, Marchand LL, Liu G, Hung RJ, Andrew AS, Kiemeney LA, Sun R, Zienolddiny S, Grankvist K, Johansson M, Caporaso NE, Cox A, Hong YC, Lazarus P, Schabath MB, Aldrich MC, Schwartz AG, Gorlov I, Purrington KS, Yang P, Liu Y, Bailey-Wilson JE, Pinney SM, Mandal D, Willey JC, Gaba C, Brennan P, Xia J, Shen H, Amos CICancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive OncologyLung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies. Cancer Epidemiol Biomarkers Prev. 2024 03 01; 33(3):389-399.Cancer Epidemiol Biomarkers Prev2024-03-01T00:00:002024Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies.true1Professor EmeritusProfessor Emeritustrue1ProfessorProfessortrue1ProfessorProfessor