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Hilda Lyn Chan

TitleGraduate Student
InstitutionBaylor College of Medicine
DepartmentImmunology & Microbiology
Address
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    F30CA268872     (CHAN, HILDA LYN)Jan 1, 2022 - Jun 30, 2025
    NIH
    Combating the Immunosuppressive Tumor Microenvironment in Triple Negative Breast Cancer: The Role of Mitochondrial Dynamics in the Polarization of Tumor-Associated Macrophages
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yuan X, Hao X, Chan HL, Zhao N, Pedroza DA, Liu F, Le K, Smith AJ, Calderon SJ, Lieu N, Soth MJ, Jones P, Zhang XH, Rosen JM, Yuan X, Hao X, Chan HL, Zhao N, Pedroza DA, Liu F, Le K, Smith AJ, Calderon SJ, Lieu N, Soth MJ, Jones P, Zhang XH, Rosen JM. CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer. JCI Insight. 2024 Sep 17; 9(20). PMID: 39287984; PMCID: PMC11533985.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Hao X, Shen Y, Liu J, Alexander A, Wu L, Xu Z, Yu L, Gao Y, Liu F, Chan HL, Li CH, Ding Y, Zhang W, Edwards DG, Chen N, Nasrazadani A, Ueno NT, Lim B, Zhang XH. Solid tumour-induced systemic immunosuppression involves dichotomous myeloid-B cell interactions. Nat Cell Biol. 2024 Nov; 26(11):1971-1983. PMID: 39266726.
      Citations:    Fields:    
    3. Xu Z, Liu F, Ding Y, Pan T, Wu YH, Liu J, Bado IL, Zhang W, Wu L, Gao Y, Hao X, Yu L, Edwards DG, Chan HL, Aguirre S, Dieffenbach MW, Chen E, Shen Y, Hoffman D, Dominguez LB, Rivas CH, Chen X, Wang H, Gugala Z, Satcher RL, Zhang XH. Unbiased metastatic niche-labeling identifies estrogen receptor-positive macrophages as a barrier of T cell infiltration during bone colonization. bioRxiv. 2024 May 10. PMID: 38765966; PMCID: PMC11100675.
      Citations:    
    4. Yuan X, Hao X, Chan HL, Zhao N, Pedroza DA, Liu F, Le K, Smith AJ, Calderon SJ, Lieu N, Soth MJ, Jones P, Zhang XH, Rosen JM. CBP/P300 BRD Inhibition Reduces Neutrophil Accumulation and Activates Antitumor Immunity in TNBC. bioRxiv. 2024 Apr 27. PMID: 38712292; PMCID: PMC11071628.
      Citations:    
    5. Chan HL, Zhang XH. Nutrient Sensing in Macrophages Linked to Reorganized Tumor Vasculature. Cancer Res. 2024 03 04; 84(5):650-651. PMID: 38241708.
      Citations:    Fields:    Translation:HumansAnimalsCells
    6. Hao X, Shen Y, Chen N, Zhang W, Valverde E, Wu L, Chan HL, Xu Z, Yu L, Gao Y, Bado I, Michie LN, Rivas CH, Dominguez LB, Aguirre S, Pingel BC, Wu YH, Liu F, Ding Y, Edwards DG, Liu J, Alexander A, Ueno NT, Hsueh PR, Tu CY, Liu LC, Chen SH, Hung MC, Lim B, Zhang XH. Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal. Cell Stem Cell. 2023 05 04; 30(5):648-664.e8. PMID: 37146584; PMCID: PMC10165729.
      Citations: 2     Fields:    Translation:HumansCells
    7. Chan HL, Zhang XH. Node foretold: Cancer cells in lymph node rewire the immune system to enable further metastases. Cancer Cell. 2022 08 08; 40(8):812-814. PMID: 35839779.
      Citations:    Fields:    
    8. Fogg JM, Judge AK, Stricker E, Chan HL, Zechiedrich L. Supercoiling and looping promote DNA base accessibility and coordination among distant sites. Nat Commun. 2021 09 28; 12(1):5683. PMID: 34584096; PMCID: PMC8478907.
      Citations: 6     Fields:    Translation:Cells
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