Connection

CHAO CHENG to Humans

This is a "connection" page, showing publications CHAO CHENG has written about Humans.
Connection Strength

1.012
  1. The prognostic effect of infiltrating immune cells is shaped by proximal M2 macrophages in lung adenocarcinoma. Mol Cancer. 2024 Sep 04; 23(1):185.
    View in: PubMed
    Score: 0.024
  2. Enhancing prognostic power in multiple myeloma using a plasma cell signature derived from single-cell RNA sequencing. Blood Cancer J. 2024 03 06; 14(1):38.
    View in: PubMed
    Score: 0.023
  3. TimiGP: An R package to depict the tumor microenvironment from bulk transcriptomics. STAR Protoc. 2023 12 15; 4(4):102742.
    View in: PubMed
    Score: 0.023
  4. TimiGP: Inferring cell-cell interactions and prognostic associations in the tumor immune microenvironment through gene pairs. Cell Rep Med. 2023 07 18; 4(7):101121.
    View in: PubMed
    Score: 0.022
  5. A combination of intrinsic and extrinsic features improves prognostic prediction in malignant pleural mesothelioma. Br J Cancer. 2022 11; 127(9):1691-1700.
    View in: PubMed
    Score: 0.021
  6. A framework to predict the applicability of Oncotype DX, MammaPrint, and E2F4 gene signatures for improving breast cancer prognostic prediction. Sci Rep. 2022 02 09; 12(1):2211.
    View in: PubMed
    Score: 0.020
  7. A lepidic gene signature predicts patient prognosis and sensitivity to immunotherapy in lung adenocarcinoma. Genome Med. 2022 01 12; 14(1):5.
    View in: PubMed
    Score: 0.020
  8. Computational modeling of chromatin accessibility identified important epigenomic regulators. BMC Genomics. 2022 Jan 08; 23(1):19.
    View in: PubMed
    Score: 0.020
  9. Clonal Hematopoiesis Mutations in Patients with Lung Cancer Are Associated with Lung Cancer Risk Factors. Cancer Res. 2022 01 15; 82(2):199-209.
    View in: PubMed
    Score: 0.020
  10. Impact of Oncotype DX testing on ER+ breast cancer treatment and survival in the first decade of use. Breast Cancer Res. 2021 07 17; 23(1):74.
    View in: PubMed
    Score: 0.019
  11. Pan-cancer association of HLA gene expression with cancer prognosis and immunotherapy efficacy. Br J Cancer. 2021 08; 125(3):422-432.
    View in: PubMed
    Score: 0.019
  12. Chr20q Amplification Defines a Distinct Molecular Subtype of Microsatellite Stable Colorectal Cancer. Cancer Res. 2021 04 15; 81(8):1977-1987.
    View in: PubMed
    Score: 0.019
  13. MYC Activity Inference Captures Diverse Mechanisms of Aberrant MYC Pathway Activation in Human Cancers. Mol Cancer Res. 2021 03; 19(3):414-428.
    View in: PubMed
    Score: 0.019
  14. Whole transcriptome signature for prognostic prediction (WTSPP): application of whole transcriptome signature for prognostic prediction in cancer. Lab Invest. 2020 10; 100(10):1356-1366.
    View in: PubMed
    Score: 0.018
  15. Systematic computational identification of prognostic cytogenetic markers in neuroblastoma. BMC Med Genomics. 2019 12 12; 12(1):192.
    View in: PubMed
    Score: 0.017
  16. Computational STAT3 activity inference reveals its roles in the pancreatic tumor microenvironment. Sci Rep. 2019 12 03; 9(1):18257.
    View in: PubMed
    Score: 0.017
  17. Statins associate with improved mortality among patients with certain histological subtypes of lung cancer. Lung Cancer. 2018 12; 126:89-96.
    View in: PubMed
    Score: 0.016
  18. Genomic Characterization of Six Virus-Associated Cancers Identifies Changes in the Tumor Immune Microenvironment and Altered Genetic Programs. Cancer Res. 2018 11 15; 78(22):6413-6423.
    View in: PubMed
    Score: 0.016
  19. A Leukocyte Infiltration Score Defined by a Gene Signature Predicts Melanoma Patient Prognosis. Mol Cancer Res. 2019 01; 17(1):109-119.
    View in: PubMed
    Score: 0.016
  20. Computational Investigation of Homologous Recombination DNA Repair Deficiency in Sporadic Breast Cancer. Sci Rep. 2017 Nov 16; 7(1):15742.
    View in: PubMed
    Score: 0.015
  21. A P53-Deficiency Gene Signature Predicts Recurrence Risk of Patients with Early-Stage Lung Adenocarcinoma. Cancer Epidemiol Biomarkers Prev. 2018 01; 27(1):86-95.
    View in: PubMed
    Score: 0.015
  22. The E2F4 prognostic signature predicts pathological response to neoadjuvant chemotherapy in breast cancer patients. BMC Cancer. 2017 05 02; 17(1):306.
    View in: PubMed
    Score: 0.014
  23. Systematic Pan-Cancer Analysis Reveals Immune Cell Interactions in the Tumor Microenvironment. Cancer Res. 2017 03 15; 77(6):1271-1282.
    View in: PubMed
    Score: 0.014
  24. Contextual Refinement of Regulatory Targets Reveals Effects on Breast Cancer Prognosis of the Regulome. PLoS Comput Biol. 2017 01; 13(1):e1005340.
    View in: PubMed
    Score: 0.014
  25. Application of pharmacologically induced transcriptomic profiles to interrogate PI3K-Akt-mTOR pathway activity associated with cancer patient prognosis. Oncotarget. 2016 Dec 20; 7(51):84142-84154.
    View in: PubMed
    Score: 0.014
  26. Application of RNAi-induced gene expression profiles for prognostic prediction in breast cancer. Genome Med. 2016 10 27; 8(1):114.
    View in: PubMed
    Score: 0.014
  27. In silico frameworks for systematic pre-clinical screening of potential anti-leukemia therapeutics. Expert Opin Drug Discov. 2016 Dec; 11(12):1213-1222.
    View in: PubMed
    Score: 0.014
  28. Adaptive immunity programmes in breast cancer. Immunology. 2017 Jan; 150(1):25-34.
    View in: PubMed
    Score: 0.014
  29. iTAR: a web server for identifying target genes of transcription factors using ChIP-seq or ChIP-chip data. BMC Genomics. 2016 08 12; 17(1):632.
    View in: PubMed
    Score: 0.014
  30. Integrative analysis of cancer genes in a functional interactome. Sci Rep. 2016 06 30; 6:29228.
    View in: PubMed
    Score: 0.014
  31. Integrated Drug Expression Analysis for leukemia: an integrated in silico and in vivo approach to drug discovery. Pharmacogenomics J. 2017 07; 17(4):351-359.
    View in: PubMed
    Score: 0.013
  32. Aberrant expression and hormonal regulation of Galectin-3 in endometriosis women with infertility. J Endocrinol Invest. 2016 Jul; 39(7):785-91.
    View in: PubMed
    Score: 0.013
  33. Integrative Genomic Analyses Yield Cell-Cycle Regulatory Programs with Prognostic Value. Mol Cancer Res. 2016 Apr; 14(4):332-43.
    View in: PubMed
    Score: 0.013
  34. Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles. Nat Commun. 2016 Jan 04; 7:10248.
    View in: PubMed
    Score: 0.013
  35. Systematic analysis of hematopoietic gene expression profiles for prognostic prediction in acute myeloid leukemia. Sci Rep. 2015 Nov 24; 5:16987.
    View in: PubMed
    Score: 0.013
  36. E2F4 Program Is Predictive of Progression and Intravesical Immunotherapy Efficacy in Bladder Cancer. Mol Cancer Res. 2015 Sep; 13(9):1316-24.
    View in: PubMed
    Score: 0.013
  37. Regulators associated with clinical outcomes revealed by DNA methylation data in breast cancer. PLoS Comput Biol. 2015 May; 11(5):e1004269.
    View in: PubMed
    Score: 0.013
  38. An approach for determining and measuring network hierarchy applied to comparing the phosphorylome and the regulome. Genome Biol. 2015 Mar 31; 16:63.
    View in: PubMed
    Score: 0.013
  39. Integrative analysis of survival-associated gene sets in breast cancer. BMC Med Genomics. 2015 Mar 12; 8:11.
    View in: PubMed
    Score: 0.012
  40. E2F4 regulatory program predicts patient survival prognosis in breast cancer. Breast Cancer Res. 2014 Dec 02; 16(6):486.
    View in: PubMed
    Score: 0.012
  41. Big data bioinformatics. J Cell Physiol. 2014 Dec; 229(12):1896-900.
    View in: PubMed
    Score: 0.012
  42. Relating gene expression evolution with CpG content changes. BMC Genomics. 2014 Aug 20; 15:693.
    View in: PubMed
    Score: 0.012
  43. Effect of estrogen receptor a binding on functional DNA methylation in breast cancer. Epigenetics. 2014 Apr; 9(4):523-32.
    View in: PubMed
    Score: 0.012
  44. Applications of bioinformatics to non-coding RNAs in the era of next-generation sequencing. Pac Symp Biocomput. 2014; 412-6.
    View in: PubMed
    Score: 0.011
  45. DPRP: a database of phenotype-specific regulatory programs derived from transcription factor binding data. Nucleic Acids Res. 2014 Jan; 42(Database issue):D178-83.
    View in: PubMed
    Score: 0.011
  46. REACTIN: regulatory activity inference of transcription factors underlying human diseases with application to breast cancer. BMC Genomics. 2013 Jul 26; 14:504.
    View in: PubMed
    Score: 0.011
  47. Transcription factor binding profiles reveal cyclic expression of human protein-coding genes and non-coding RNAs. PLoS Comput Biol. 2013; 9(7):e1003132.
    View in: PubMed
    Score: 0.011
  48. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012 Sep 06; 489(7414):57-74.
    View in: PubMed
    Score: 0.010
  49. Understanding transcriptional regulation by integrative analysis of transcription factor binding data. Genome Res. 2012 Sep; 22(9):1658-67.
    View in: PubMed
    Score: 0.010
  50. A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol. 2011 Apr; 9(4):e1001046.
    View in: PubMed
    Score: 0.010
  51. A statistical framework for modeling gene expression using chromatin features and application to modENCODE datasets. Genome Biol. 2011; 12(2):R15.
    View in: PubMed
    Score: 0.009
  52. The relationship between the evolution of microRNA targets and the length of their UTRs. BMC Genomics. 2009 Sep 14; 10:431.
    View in: PubMed
    Score: 0.009
  53. mRNA expression profiles show differential regulatory effects of microRNAs between estrogen receptor-positive and estrogen receptor-negative breast cancer. Genome Biol. 2009; 10(9):R90.
    View in: PubMed
    Score: 0.008
  54. Systematic identification of transcription factors associated with patient survival in cancers. BMC Genomics. 2009 May 15; 10:225.
    View in: PubMed
    Score: 0.008
  55. Inferring microRNA activities by combining gene expression with microRNA target prediction. PLoS One. 2008 Apr 23; 3(4):e1989.
    View in: PubMed
    Score: 0.008
  56. Sub-array normalization subject to differentiation. Nucleic Acids Res. 2005; 33(17):5565-73.
    View in: PubMed
    Score: 0.006
  57. Assessment of human leukocyte antigen-based neoantigen presentation to determine pan-cancer response to immunotherapy. Nat Commun. 2024 Feb 08; 15(1):1199.
    View in: PubMed
    Score: 0.006
  58. Cloning, expression and characterization of a novel human VMP gene. Mol Biol Rep. 2002 Sep; 29(3):281-6.
    View in: PubMed
    Score: 0.005
  59. Predicting clinical outcomes of cancer patients with a p53 deficiency gene signature. Sci Rep. 2022 01 25; 12(1):1317.
    View in: PubMed
    Score: 0.005
  60. Cloning and characterization of a novel human transcription factor AP-2 beta like gene (TFAP2BL1). Int J Biochem Cell Biol. 2002 Jan; 34(1):78-86.
    View in: PubMed
    Score: 0.005
  61. Resident memory CD8+ T?cells in regional lymph nodes mediate immunity to metastatic melanoma. Immunity. 2021 09 14; 54(9):2117-2132.e7.
    View in: PubMed
    Score: 0.005
  62. Multifactorial Deep Learning Reveals Pan-Cancer Genomic Tumor Clusters with Distinct Immunogenomic Landscape and Response to Immunotherapy. Clin Cancer Res. 2020 06 15; 26(12):2908-2920.
    View in: PubMed
    Score: 0.004
  63. CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies. Cell Rep. 2019 12 10; 29(11):3405-3420.e5.
    View in: PubMed
    Score: 0.004
  64. A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition. Clin Cancer Res. 2020 01 01; 26(1):159-170.
    View in: PubMed
    Score: 0.004
  65. Single-cell RNA sequencing reveals the impact of chromosomal instability on glioblastoma cancer stem cells. BMC Med Genomics. 2019 05 31; 12(1):79.
    View in: PubMed
    Score: 0.004
  66. Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment. Cancer Immunol Res. 2019 07; 7(7):1079-1090.
    View in: PubMed
    Score: 0.004
  67. H22954, a novel long non-coding RNA down-regulated in AML, inhibits cancer growth in a BCL-2-dependent mechanism. Cancer Lett. 2019 07 10; 454:26-36.
    View in: PubMed
    Score: 0.004
  68. Molecular and epigenetic profiles of BRCA1-like hormone-receptor-positive breast tumors identified with development and application of a copy-number-based classifier. Breast Cancer Res. 2019 01 25; 21(1):14.
    View in: PubMed
    Score: 0.004
  69. Novel putative drugs and key initiating genes for neurodegenerative disease determined using network-based genetic integrative analysis. J Cell Biochem. 2019 04; 120(4):5459-5471.
    View in: PubMed
    Score: 0.004
  70. Identification of gene expression levels in primary melanoma associated with clinically meaningful characteristics. Melanoma Res. 2018 10; 28(5):380-389.
    View in: PubMed
    Score: 0.004
  71. Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER+ breast cancer. FASEB J. 2019 02; 33(2):1644-1657.
    View in: PubMed
    Score: 0.004
  72. VISTA expression on tumor-infiltrating inflammatory cells in primary cutaneous melanoma correlates with poor disease-specific survival. Cancer Immunol Immunother. 2018 Jul; 67(7):1113-1121.
    View in: PubMed
    Score: 0.004
  73. A recombinant lentiviral PDGF-driven mouse model of proneural glioblastoma. Neuro Oncol. 2018 02 19; 20(3):332-342.
    View in: PubMed
    Score: 0.004
  74. Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. J Exp Med. 2018 03 05; 215(3):895-910.
    View in: PubMed
    Score: 0.004
  75. Decreased expression of FOXA2 promotes eutopic endometrial cell proliferation and migration in patients with endometriosis. Reprod Biomed Online. 2018 Feb; 36(2):181-187.
    View in: PubMed
    Score: 0.004
  76. Reconstruction of enhancer-target networks in 935 samples of human primary cells, tissues and cell lines. Nat Genet. 2017 Oct; 49(10):1428-1436.
    View in: PubMed
    Score: 0.004
  77. Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing. PLoS Genet. 2017 Jul; 13(7):e1006870.
    View in: PubMed
    Score: 0.004
  78. Population effect model identifies gene expression predictors of survival outcomes in lung adenocarcinoma for both Caucasian and Asian patients. PLoS One. 2017; 12(4):e0175850.
    View in: PubMed
    Score: 0.004
  79. Immunoregulatory functions of VISTA. Immunol Rev. 2017 03; 276(1):66-79.
    View in: PubMed
    Score: 0.004
  80. Insulin-Mediated Signaling Facilitates Resistance to PDGFR Inhibition in Proneural hPDGFB-Driven Gliomas. Mol Cancer Ther. 2017 04; 16(4):705-716.
    View in: PubMed
    Score: 0.004
  81. Inferring condition-specific targets of human TF-TF complexes using ChIP-seq data. BMC Genomics. 2017 01 10; 18(1):61.
    View in: PubMed
    Score: 0.004
  82. MYC Mediates mRNA Cap Methylation of Canonical Wnt/?-Catenin Signaling Transcripts By Recruiting CDK7 and RNA Methyltransferase. Mol Cancer Res. 2017 02; 15(2):213-224.
    View in: PubMed
    Score: 0.004
  83. Complex Patterns of Association between Pleiotropy and Transcription Factor Evolution. Genome Biol Evol. 2016 10 23; 8(10):3159-3170.
    View in: PubMed
    Score: 0.003
  84. GLITTER: a web-based application for gene link inspection through tissue-specific coexpression. Sci Rep. 2016 09 14; 6:33460.
    View in: PubMed
    Score: 0.003
  85. Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics. Mol Cell Proteomics. 2016 07; 15(7):2448-61.
    View in: PubMed
    Score: 0.003
  86. PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-Mediated Survival of Proneural Glioma Cells. Cancer Res. 2016 05 15; 76(10):2964-76.
    View in: PubMed
    Score: 0.003
  87. CircNet: a database of circular RNAs derived from transcriptome sequencing data. Nucleic Acids Res. 2016 Jan 04; 44(D1):D209-15.
    View in: PubMed
    Score: 0.003
  88. Integrative Analysis Reveals Regulatory Programs in Endometriosis. Reprod Sci. 2015 Sep; 22(9):1060-72.
    View in: PubMed
    Score: 0.003
  89. Loregic: a method to characterize the cooperative logic of regulatory factors. PLoS Comput Biol. 2015 Apr; 11(4):e1004132.
    View in: PubMed
    Score: 0.003
  90. p53 and ?Np63a Coregulate the Transcriptional and Cellular Response to TGF? and BMP Signals. Mol Cancer Res. 2015 Apr; 13(4):732-42.
    View in: PubMed
    Score: 0.003
  91. Unsupervised feature construction and knowledge extraction from genome-wide assays of breast cancer with denoising autoencoders. Pac Symp Biocomput. 2015; 132-43.
    View in: PubMed
    Score: 0.003
  92. Comparative analysis of the transcriptome across distant species. Nature. 2014 Aug 28; 512(7515):445-8.
    View in: PubMed
    Score: 0.003
  93. Comparative analysis of regulatory information and circuits across distant species. Nature. 2014 Aug 28; 512(7515):453-6.
    View in: PubMed
    Score: 0.003
  94. Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation. Epigenetics. 2014 Feb; 9(2):268-75.
    View in: PubMed
    Score: 0.003
  95. Association of gamma-aminobutyric acid A receptor a2 gene (GABRA2) with alcohol use disorder. Neuropsychopharmacology. 2014 Mar; 39(4):907-18.
    View in: PubMed
    Score: 0.003
  96. Identification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors. Mol Biol Cell. 2013 Dec; 24(23):3634-50.
    View in: PubMed
    Score: 0.003
  97. Paeonol induces apoptosis in human ovarian cancer cells. Acta Histochem. 2013 Oct; 115(8):835-9.
    View in: PubMed
    Score: 0.003
  98. An MLL-dependent network sustains hematopoiesis. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):12000-5.
    View in: PubMed
    Score: 0.003
  99. Machine learning and genome annotation: a match meant to be? Genome Biol. 2013 May 29; 14(5):205.
    View in: PubMed
    Score: 0.003
  100. Discovering chromatin motifs using FAIRE sequencing and the human diploid genome. BMC Genomics. 2013 May 08; 14:310.
    View in: PubMed
    Score: 0.003
  101. A comprehensive nuclear receptor network for breast cancer cells. Cell Rep. 2013 Feb 21; 3(2):538-51.
    View in: PubMed
    Score: 0.003
  102. Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors. Genome Biol. 2012 Sep 26; 13(9):R48.
    View in: PubMed
    Score: 0.003
  103. Architecture of the human regulatory network derived from ENCODE data. Nature. 2012 Sep 06; 489(7414):91-100.
    View in: PubMed
    Score: 0.003
  104. The antiapoptotic effect of galectin-3 in human endometrial cells under the regulation of estrogen and progesterone. Biol Reprod. 2012 Aug; 87(2):39.
    View in: PubMed
    Score: 0.003
  105. Modeling gene expression using chromatin features in various cellular contexts. Genome Biol. 2012 Jun 13; 13(9):R53.
    View in: PubMed
    Score: 0.003
  106. Average rank-based score to measure deregulation of molecular pathway gene sets. PLoS One. 2011; 6(11):e27579.
    View in: PubMed
    Score: 0.002
  107. Hormonal regulation of galectin 3 in trophoblasts and its effects on endometrium. Reprod Sci. 2011 Nov; 18(11):1118-27.
    View in: PubMed
    Score: 0.002
  108. Understanding protein evolutionary rate by integrating gene co-expression with protein interactions. BMC Syst Biol. 2010 Dec 30; 4:179.
    View in: PubMed
    Score: 0.002
  109. Segmental duplications in the human genome reveal details of pseudogene formation. Nucleic Acids Res. 2010 Nov; 38(20):6997-7007.
    View in: PubMed
    Score: 0.002
  110. Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis. PLoS Comput Biol. 2010 Apr 01; 6(4):e1000730.
    View in: PubMed
    Score: 0.002
  111. Isolation and characterization of a human putative receptor protein kinase cDNA STYK1. Mol Biol Rep. 2003 Jun; 30(2):91-6.
    View in: PubMed
    Score: 0.001
  112. Isolation and characterization of a novel human putative anemia-related gene homologous to mouse sideroflexin. Biochem Genet. 2003 Apr; 41(3-4):119-25.
    View in: PubMed
    Score: 0.001
  113. Identification and characterization of AGTRAP, a human homolog of murine Angiotensin II Receptor-Associated Protein (Agtrap). Int J Biochem Cell Biol. 2002 Jan; 34(1):93-102.
    View in: PubMed
    Score: 0.001
  114. Cloning, expression and characterization of a novel human REPS1 gene. Biochim Biophys Acta. 2001 Dec 03; 1522(2):118-21.
    View in: PubMed
    Score: 0.001
  115. Cloning and characterization of a novel human TEKTIN1 gene. Int J Biochem Cell Biol. 2001 Dec; 33(12):1172-82.
    View in: PubMed
    Score: 0.001
  116. Molecular cloning, structure and expression of a novel nuclear RNA-binding cyclophilin-like gene (PPIL4) from human fetal brain. Cytogenet Cell Genet. 2001; 95(1-2):43-7.
    View in: PubMed
    Score: 0.001
  117. A novel human hydroxysteroid dehydrogenase like 1 gene (HSDL1) is highly expressed in reproductive tissues. Mol Biol Rep. 2001; 28(4):185-91.
    View in: PubMed
    Score: 0.001
  118. Molecular cloning and characterization of a novel Dehydrogenase/reductase (SDR family) member 1 genea from human fetal brain. Mol Biol Rep. 2001; 28(4):193-8.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.