D059748PhysiologyG02.111.720G03.8122613720.833684ProteolysisFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonLeukemiaLymphoma-MyelomaMolecular & Cellular OncologyMD AndersonMIEN-CHIEHUNGMIEN-CHIE HUNG8427HUNG, MIEN-CHIEProfessorJASON ROBERTWESTINJASON ROBERT WESTIN9367WESTIN, JASON ROBERTAssistant Professor74Professor10Assistant Professor54Instructor46Distinguished Emeritus ProfessorKAPILBHALLAKAPIL BHALLA11899BHALLA, KAPILProfessorDepartment of MedicineMedicine-NephrologyBaylor College of MedicineWILLIAMMITCHWILLIAM MITCH0.000000000000000.00000000000000900MITCH, WILLIAMDistinguished Emeritus Professor1.17550.021356261research area of0.9894290.102465247subject area forXINLIXIN LI15214LI, XINInstructor33369705Yang X, Yin H, Kim RD, Fleming JB, Xie HTargeted oncologyPreclinical and Clinical Advances of Targeted Protein Degradation as a Novel Cancer Therapeutic Strategy: An Oncologist Perspective. Target Oncol. 2021 01; 16(1):1-12.Target Oncol2021-01-01T00:00:002021Preclinical and Clinical Advances of Targeted Protein Degradation as a Novel Cancer Therapeutic Strategy: An Oncologist Perspective.33436616Rizzolo K, Yu AYH, Ologbenla A, Kim SR, Zhu H, Ishimori K, Thibault G, Leung E, Zhang YW, Teng M, Haniszewski M, Miah N, Phanse S, Minic Z, Lee S, Caballero JD, Babu M, Tsai FTF, Saio T, Houry WANature communicationsFunctional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex. Nat Commun. 2021 01 12; 12(1):281.Nat Commun2021-01-12T00:00:002021Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex.33654205Fiskus W, Mill CP, Perera D, Birdwell C, Deng Q, Yang H, Lara BH, Jain N, Burger J, Ferrajoli A, Davis JA, Saenz DT, Jin W, Coarfa C, Crews CM, Green MR, Khoury JD, Bhalla KNLeukemiaBET proteolysis targeted chimera-based therapy of novel models of Richter Transformation-diffuse large B-cell lymphoma. Leukemia. 2021 09; 35(9):2621-2634.Leukemia2021-03-02T00:00:002021BET proteolysis targeted chimera-based therapy of novel models of Richter Transformation-diffuse large B-cell lymphoma.33547076Koduri V, Duplaquet L, Lampson BL, Wang AC, Sabet AH, Ishoey M, Paulk J, Teng M, Harris IS, Endress JE, Liu X, Dasilva E, Paulo JA, Briggs KJ, Doench JG, Ott CJ, Zhang T, Donovan KA, Fischer ES, Gygi SP, Gray NS, Bradner J, Medin JA, Buhrlage SJ, Oser MG, Kaelin WGScience advancesTargeting oncoproteins with a positive selection assay for protein degraders. Sci Adv. 2021 02; 7(6).Sci Adv2021-02-05T00:00:002021Targeting oncoproteins with a positive selection assay for protein degraders.true1InstructorInstructorDepartment of Biochemistry and Molecular PharmacologyBiochemistry & Mol Pharmacologytrue1Distinguished Emeritus ProfessorDistinguished Emeritus Professor38301021Davis RE, Westin JRScience (New York, N.Y.)Degradation trumps mutations in cancer. Science. 2024 Feb 02; 383(6682):480-481.Science2024-02-01T00:00:002024Degradation trumps mutations in cancer.true1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1ProfessorProfessor