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Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription.
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Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription.
Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. Elife. 2019 04 17; 8.
View in:
PubMed
subject areas
Animals
Ataxin-3
Cell Line
DNA Repair
DNA Repair Enzymes
DNA-Directed RNA Polymerases
Humans
Huntingtin Protein
Mice, Transgenic
Mutant Proteins
Peptide Fragments
Phosphotransferases (Alcohol Group Acceptor)
Protein Binding
Protein Multimerization
Repressor Proteins
Sialoglycoproteins
Transcription, Genetic
authors with profiles
TETSUO ASHIZAWA