WILLIAM MITCH to Muscle, Skeletal
This is a "connection" page, showing publications WILLIAM MITCH has written about Muscle, Skeletal.
Connection Strength
5.162
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Pharmacokinetics and pharmacodynamics of TTI-101, a STAT3 inhibitor that blocks muscle proteolysis in rats with chronic kidney disease. Am J Physiol Renal Physiol. 2020 07 01; 319(1):F84-F92.
Score: 0.436
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Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40. Am J Physiol Endocrinol Metab. 2020 05 01; 318(5):E625-E635.
Score: 0.428
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Inhibition of Stat3 activation suppresses caspase-3 and the ubiquitin-proteasome system, leading to preservation of muscle mass in cancer cachexia. J Biol Chem. 2015 Apr 24; 290(17):11177-87.
Score: 0.304
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Can muscle-kidney crosstalk slow progression of CKD? J Am Soc Nephrol. 2014 Dec; 25(12):2681-3.
Score: 0.290
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Mechanisms of muscle wasting in chronic kidney disease. Nat Rev Nephrol. 2014 Sep; 10(9):504-16.
Score: 0.289
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Muscle wasting from kidney failure-a model for catabolic conditions. Int J Biochem Cell Biol. 2013 Oct; 45(10):2230-8.
Score: 0.270
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Signal regulatory protein-a interacts with the insulin receptor contributing to muscle wasting in chronic kidney disease. Kidney Int. 2013 Aug; 84(2):308-16.
Score: 0.264
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Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease. FASEB J. 2011 May; 25(5):1653-63.
Score: 0.228
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PTEN inhibition improves muscle regeneration in mice fed a high-fat diet. Diabetes. 2010 Jun; 59(6):1312-20.
Score: 0.214
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Review of muscle wasting associated with chronic kidney disease. Am J Clin Nutr. 2010 Apr; 91(4):1128S-1132S.
Score: 0.214
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Chemokine CXCL16 regulates neutrophil and macrophage infiltration into injured muscle, promoting muscle regeneration. Am J Pathol. 2009 Dec; 175(6):2518-27.
Score: 0.209
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PTEN expression contributes to the regulation of muscle protein degradation in diabetes. Diabetes. 2007 Oct; 56(10):2449-56.
Score: 0.178
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Malnutrition is an unusual cause of decreased muscle mass in chronic kidney disease. J Ren Nutr. 2007 Jan; 17(1):66-9.
Score: 0.172
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Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: implications for muscle atrophy. J Am Soc Nephrol. 2006 May; 17(5):1388-94.
Score: 0.164
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Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions. J Clin Invest. 2004 Jan; 113(1):115-23.
Score: 0.140
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Systemic inflammation is associated with exaggerated skeletal muscle protein catabolism in maintenance hemodialysis patients. JCI Insight. 2017 11 16; 2(22).
Score: 0.091
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Myokine mediated muscle-kidney crosstalk suppresses metabolic reprogramming and fibrosis in damaged kidneys. Nat Commun. 2017 11 14; 8(1):1493.
Score: 0.091
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The pathway to muscle fibrosis depends on myostatin stimulating the differentiation of fibro/adipogenic progenitor cells in chronic kidney disease. Kidney Int. 2017 01; 91(1):119-128.
Score: 0.084
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Inhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues. Int J Obes (Lond). 2016 Mar; 40(3):434-442.
Score: 0.079
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Adverse Effects of Sporadic Dialysis on Body Composition. Nephron. 2015; 131(1):73-7.
Score: 0.078
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MicroRNA-29 induces cellular senescence in aging muscle through multiple signaling pathways. Aging (Albany NY). 2014 Mar; 6(3):160-75.
Score: 0.071
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Stat3 activation links a C/EBPd to myostatin pathway to stimulate loss of muscle mass. Cell Metab. 2013 Sep 03; 18(3):368-79.
Score: 0.068
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Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia. Int J Biochem Cell Biol. 2013 Oct; 45(10):2322-32.
Score: 0.067
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Angiotensin II upregulates protein phosphatase 2Ca and inhibits AMP-activated protein kinase signaling and energy balance leading to skeletal muscle wasting. Hypertension. 2011 Oct; 58(4):643-9.
Score: 0.059
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Caspase-3 cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity. J Biol Chem. 2010 Jul 09; 285(28):21249-57.
Score: 0.054
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Satellite cell dysfunction and impaired IGF-1 signaling cause CKD-induced muscle atrophy. J Am Soc Nephrol. 2010 Mar; 21(3):419-27.
Score: 0.053
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Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice. J Clin Invest. 2009 Oct; 119(10):3059-69.
Score: 0.052
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Exercise ameliorates chronic kidney disease-induced defects in muscle protein metabolism and progenitor cell function. Kidney Int. 2009 Oct; 76(7):751-9.
Score: 0.051
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Development of a diagnostic method for detecting increased muscle protein degradation in patients with catabolic conditions. J Am Soc Nephrol. 2006 Nov; 17(11):3233-9.
Score: 0.042
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Tissue-specific regulation of ubiquitin (UbC) transcription by glucocorticoids: in vivo and in vitro analyses. Am J Physiol Renal Physiol. 2007 Feb; 292(2):F660-6.
Score: 0.042
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Effect of bicarbonate on muscle protein in patients receiving hemodialysis. Am J Kidney Dis. 2006 Sep; 48(3):419-29.
Score: 0.042
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Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. Endocrinology. 2006 Sep; 147(9):4160-8.
Score: 0.041
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Cellular signals activating muscle proteolysis in chronic kidney disease: a two-stage process. Int J Biochem Cell Biol. 2005 Oct; 37(10):2147-55.
Score: 0.039
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Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting. J Clin Invest. 2005 Feb; 115(2):451-8.
Score: 0.038
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The evidence against malnutrition as a prominent problem for chronic dialysis patients. Semin Dial. 2004 Nov-Dec; 17(6):427-31.
Score: 0.037
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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J. 2004 Jan; 18(1):39-51.
Score: 0.035
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Nutrition in CAPD: serum bicarbonate and the ubiquitin-proteasome system in muscle. Kidney Int. 2002 Apr; 61(4):1286-92.
Score: 0.031
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Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1. J Biol Chem. 2002 May 10; 277(19):16673-81.
Score: 0.031
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Pathophysiological mechanisms leading to muscle loss in chronic kidney disease. Nat Rev Nephrol. 2022 03; 18(3):138-152.
Score: 0.030
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Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk. J Cachexia Sarcopenia Muscle. 2019 12; 10(6):1210-1227.
Score: 0.026
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Myostatin/activin pathway antagonism: molecular basis and therapeutic potential. Int J Biochem Cell Biol. 2013 Oct; 45(10):2333-47.
Score: 0.017
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Ghrelin treatment of chronic kidney disease: improvements in lean body mass and cytokine profile. Endocrinology. 2008 Feb; 149(2):827-35.
Score: 0.011