WILLIAM MITCH to Animals
This is a "connection" page, showing publications WILLIAM MITCH has written about Animals.
Connection Strength
0.903
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Mechanisms Regulating Muscle Protein Synthesis in CKD. J Am Soc Nephrol. 2020 11; 31(11):2573-2587.
Score: 0.039
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Pharmacokinetics and pharmacodynamics of TTI-101, a STAT3 inhibitor that blocks muscle proteolysis in rats with chronic kidney disease. Am J Physiol Renal Physiol. 2020 07 01; 319(1):F84-F92.
Score: 0.039
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Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40. Am J Physiol Endocrinol Metab. 2020 05 01; 318(5):E625-E635.
Score: 0.038
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Parathyroid hormone stimulates adipose tissue browning: a pathway to muscle wasting. Curr Opin Clin Nutr Metab Care. 2017 May; 20(3):153-157.
Score: 0.031
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Inhibition of Stat3 activation suppresses caspase-3 and the ubiquitin-proteasome system, leading to preservation of muscle mass in cancer cachexia. J Biol Chem. 2015 Apr 24; 290(17):11177-87.
Score: 0.027
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Can muscle-kidney crosstalk slow progression of CKD? J Am Soc Nephrol. 2014 Dec; 25(12):2681-3.
Score: 0.026
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Stat3 activation links a C/EBPd to myostatin pathway to stimulate loss of muscle mass. Cell Metab. 2013 Sep 03; 18(3):368-79.
Score: 0.024
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Muscle wasting from kidney failure-a model for catabolic conditions. Int J Biochem Cell Biol. 2013 Oct; 45(10):2230-8.
Score: 0.024
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Signal regulatory protein-a interacts with the insulin receptor contributing to muscle wasting in chronic kidney disease. Kidney Int. 2013 Aug; 84(2):308-16.
Score: 0.024
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Targeting the myostatin signaling pathway to treat muscle wasting diseases. Curr Opin Support Palliat Care. 2011 Dec; 5(4):334-41.
Score: 0.022
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Decreased miR-29 suppresses myogenesis in CKD. J Am Soc Nephrol. 2011 Nov; 22(11):2068-76.
Score: 0.021
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Proteins and renal fibrosis: low-protein diets induce Kruppel-like factor-15, limiting renal fibrosis. Kidney Int. 2011 May; 79(9):933-4.
Score: 0.021
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Proteolysis by the ubiquitin-proteasome system and kidney disease. J Am Soc Nephrol. 2011 May; 22(5):821-4.
Score: 0.021
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Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease. FASEB J. 2011 May; 25(5):1653-63.
Score: 0.020
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PTEN inhibition improves muscle regeneration in mice fed a high-fat diet. Diabetes. 2010 Jun; 59(6):1312-20.
Score: 0.019
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Satellite cell dysfunction and impaired IGF-1 signaling cause CKD-induced muscle atrophy. J Am Soc Nephrol. 2010 Mar; 21(3):419-27.
Score: 0.019
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Chemokine CXCL16 regulates neutrophil and macrophage infiltration into injured muscle, promoting muscle regeneration. Am J Pathol. 2009 Dec; 175(6):2518-27.
Score: 0.019
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Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice. J Clin Invest. 2009 Oct; 119(10):3059-69.
Score: 0.018
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Exercise ameliorates chronic kidney disease-induced defects in muscle protein metabolism and progenitor cell function. Kidney Int. 2009 Oct; 76(7):751-9.
Score: 0.018
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IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting. J Am Soc Nephrol. 2009 Mar; 20(3):604-12.
Score: 0.018
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Ubiquitin, proteasomes and proteolytic mechanisms activated by kidney disease. Biochim Biophys Acta. 2008 Dec; 1782(12):795-9.
Score: 0.017
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PTEN expression contributes to the regulation of muscle protein degradation in diabetes. Diabetes. 2007 Oct; 56(10):2449-56.
Score: 0.016
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Malnutrition is an unusual cause of decreased muscle mass in chronic kidney disease. J Ren Nutr. 2007 Jan; 17(1):66-9.
Score: 0.015
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Proteolytic mechanisms, not malnutrition, cause loss of muscle mass in kidney failure. J Ren Nutr. 2006 Jul; 16(3):208-11.
Score: 0.015
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Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. Endocrinology. 2006 Sep; 147(9):4160-8.
Score: 0.015
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Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: implications for muscle atrophy. J Am Soc Nephrol. 2006 May; 17(5):1388-94.
Score: 0.015
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Cellular signals activating muscle proteolysis in chronic kidney disease: a two-stage process. Int J Biochem Cell Biol. 2005 Oct; 37(10):2147-55.
Score: 0.014
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Identification of pathways controlling muscle protein metabolism in uremia and other catabolic conditions. Curr Opin Nephrol Hypertens. 2005 Jul; 14(4):378-82.
Score: 0.014
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Cachexia in chronic kidney disease: a link to defective central nervous system control of appetite. J Clin Invest. 2005 Jun; 115(6):1476-8.
Score: 0.014
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Strategies for suppressing muscle atrophy in chronic kidney disease: mechanisms activating distinct proteolytic systems. J Ren Nutr. 2005 Jan; 15(1):23-7.
Score: 0.013
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Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase. J Am Soc Nephrol. 2004 Jun; 15(6):1537-45.
Score: 0.013
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Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions. J Clin Invest. 2004 Jan; 113(1):115-23.
Score: 0.012
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Chronic kidney disease promotes atrial fibrillation via inflammasome pathway activation. J Clin Invest. 2023 10 02; 133(19).
Score: 0.012
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Mechanisms activating proteolysis to cause muscle atrophy in catabolic conditions. J Ren Nutr. 2003 Apr; 13(2):149-52.
Score: 0.012
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SIRPa Mediates IGF1 Receptor in Cardiomyopathy Induced by Chronic Kidney Disease. Circ Res. 2022 07 22; 131(3):207-221.
Score: 0.011
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PDGFRA in vascular adventitial MSCs promotes neointima formation in arteriovenous fistula in chronic kidney disease. JCI Insight. 2020 11 05; 5(21).
Score: 0.010
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Decreased Jagged1 expression in vascular smooth muscle cells delays endothelial regeneration in arteriovenous graft. Cardiovasc Res. 2020 11 01; 116(13):2142-2155.
Score: 0.010
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Phosphoinositide 3-kinase ? deficiency attenuates kidney injury and fibrosis in angiotensin II-induced hypertension. Nephrol Dial Transplant. 2020 09 01; 35(9):1491-1500.
Score: 0.010
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Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk. J Cachexia Sarcopenia Muscle. 2019 12; 10(6):1210-1227.
Score: 0.009
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Notch signaling in bone marrow-derived FSP-1?cells initiates neointima formation in arteriovenous?fistulas. Kidney Int. 2019 06; 95(6):1347-1358.
Score: 0.009
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Systemic inflammation is associated with exaggerated skeletal muscle protein catabolism in maintenance hemodialysis patients. JCI Insight. 2017 11 16; 2(22).
Score: 0.008
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Myokine mediated muscle-kidney crosstalk suppresses metabolic reprogramming and fibrosis in damaged kidneys. Nat Commun. 2017 11 14; 8(1):1493.
Score: 0.008
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The IL-4 receptor a has a critical role in bone marrow-derived fibroblast activation and renal fibrosis. Kidney Int. 2017 12; 92(6):1433-1443.
Score: 0.008
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AMP-activated protein kinase/myocardin-related transcription factor-A signaling regulates fibroblast activation and renal fibrosis. Kidney Int. 2018 01; 93(1):81-94.
Score: 0.008
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The pathway to muscle fibrosis depends on myostatin stimulating the differentiation of fibro/adipogenic progenitor cells in chronic kidney disease. Kidney Int. 2017 01; 91(1):119-128.
Score: 0.008
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Inhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues. Int J Obes (Lond). 2016 Mar; 40(3):434-442.
Score: 0.007
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CKD Stimulates Muscle Protein Loss Via Rho-associated Protein Kinase 1 Activation. J Am Soc Nephrol. 2016 Feb; 27(2):509-19.
Score: 0.007
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JAK3/STAT6 Stimulates Bone Marrow-Derived Fibroblast Activation in Renal Fibrosis. J Am Soc Nephrol. 2015 Dec; 26(12):3060-71.
Score: 0.007
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Migration of smooth muscle cells from the arterial anastomosis of arteriovenous fistulas requires Notch activation to form neointima. Kidney Int. 2015 Sep; 88(3):490-502.
Score: 0.007
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FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice. Endocrinology. 2015 Jun; 156(6):2200-10.
Score: 0.007
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Protective role of insulin-like growth factor-1 receptor in endothelial cells against unilateral ureteral obstruction-induced renal fibrosis. Am J Pathol. 2015 May; 185(5):1234-50.
Score: 0.007
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Urea and Ammonia Metabolism and the Control of Renal Nitrogen Excretion. Clin J Am Soc Nephrol. 2015 Aug 07; 10(8):1444-58.
Score: 0.006
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MicroRNA-29 induces cellular senescence in aging muscle through multiple signaling pathways. Aging (Albany NY). 2014 Mar; 6(3):160-75.
Score: 0.006
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Blocking Notch in endothelial cells prevents arteriovenous fistula failure despite CKD. J Am Soc Nephrol. 2014 Apr; 25(4):773-83.
Score: 0.006
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Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia. Int J Biochem Cell Biol. 2013 Oct; 45(10):2322-32.
Score: 0.006
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Myostatin/activin pathway antagonism: molecular basis and therapeutic potential. Int J Biochem Cell Biol. 2013 Oct; 45(10):2333-47.
Score: 0.006
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Loss of glutathione S-transferase A4 accelerates obstruction-induced tubule damage and renal fibrosis. J Pathol. 2012 Dec; 228(4):448-58.
Score: 0.006
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Protein-restricted diets plus keto/amino acids--a valid therapeutic approach for chronic kidney disease patients. J Ren Nutr. 2012 Mar; 22(2 Suppl):S1-21.
Score: 0.005
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Requirement of argininosuccinate lyase for systemic nitric oxide production. Nat Med. 2011 Nov 13; 17(12):1619-26.
Score: 0.005
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Angiotensin II upregulates protein phosphatase 2Ca and inhibits AMP-activated protein kinase signaling and energy balance leading to skeletal muscle wasting. Hypertension. 2011 Oct; 58(4):643-9.
Score: 0.005
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Caspase-3 cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity. J Biol Chem. 2010 Jul 09; 285(28):21249-57.
Score: 0.005
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Ghrelin treatment of chronic kidney disease: improvements in lean body mass and cytokine profile. Endocrinology. 2008 Feb; 149(2):827-35.
Score: 0.004
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Tissue-specific regulation of ubiquitin (UbC) transcription by glucocorticoids: in vivo and in vitro analyses. Am J Physiol Renal Physiol. 2007 Feb; 292(2):F660-6.
Score: 0.004
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Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting. J Clin Invest. 2005 Feb; 115(2):451-8.
Score: 0.003
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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J. 2004 Jan; 18(1):39-51.
Score: 0.003
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Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest. 2003 Apr; 111(8):1201-9.
Score: 0.003
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Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1. J Biol Chem. 2002 May 10; 277(19):16673-81.
Score: 0.003