PRZEMYSLAWSZAFRANSKIPRZEMYSLAW SZAFRANSKI0.000000000000000.000000000000004785SZAFRANSKI, PRZEMYSLAWAssociate Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 815343Authorship 156607Authorship 1601561Authorship 1606083Authorship 162534224824130Szafranski P, Von Allmen GK, Graham BH, Wilfong AA, Kang SH, Ferreira JA, Upton SJ, Moeschler JB, Bi W, Rosenfeld JA, Shaffer LG, Wai Cheung S, Stankiewicz P, Lalani SREuropean journal of human genetics : EJHG6q22.1 microdeletion and susceptibility to pediatric epilepsy. Eur J Hum Genet. 2015 Feb; 23(2):173-9.Eur J Hum Genet2014-05-14T00:00:0020146q22.1 microdeletion and susceptibility to pediatric epilepsy.25472632Dharmadhikari AV, Gambin T, Szafranski P, Cao W, Probst FJ, Jin W, Fang P, Gogolewski K, Gambin A, George-Abraham JK, Golla S, Boidein F, Duban-Bedu B, Delobel B, Andrieux J, Becker K, Holinski-Feder E, Cheung SW, Stankiewicz PBMC medical geneticsMolecular and clinical analyses of 16q24.1 duplications involving FOXF1 identify an evolutionarily unstable large minisatellite. BMC Med Genet. 2014 Dec 04; 15:128.BMC Med Genet2014-12-04T00:00:002014Molecular and clinical analyses of 16q24.1 duplications involving FOXF1 identify an evolutionarily unstable large minisatellite.25613453Startek M, Szafranski P, Gambin T, Campbell IM, Hixson P, Shaw CA, Stankiewicz P, Gambin ANucleic acids researchGenome-wide analyses of LINE-LINE-mediated nonallelic homologous recombination. Nucleic Acids Res. 2015 Feb 27; 43(4):2188-98.Nucleic Acids Res2015-01-22T00:00:002015Genome-wide analyses of LINE-LINE-mediated nonallelic homologous recombination.Experimental TherapeuticsMD AndersonGEORGE ACALINGEORGE A CALIN9408CALIN, GEORGE AProfessorAuthorship 537702Authorship 564681Authorship 2915291Authorship 3040444Authorship 304251225315662Szafranski P, Golla S, Jin W, Fang P, Hixson P, Matalon R, Kinney D, Bock HG, Craigen W, Smith JL, Bi W, Patel A, Wai Cheung S, Bacino CA, Stankiewicz PEuropean journal of human genetics : EJHGNeurodevelopmental and neurobehavioral characteristics in males and females with CDKL5 duplications. Eur J Hum Genet. 2015 Jul; 23(7):915-21.Eur J Hum Genet2014-10-15T00:00:002014Neurodevelopmental and neurobehavioral characteristics in males and females with CDKL5 duplications.26059046Smyk M, Roeder E, Cheung SW, Szafranski P, Stankiewicz PAmerican journal of medical genetics. Part AA de novo 1.58?Mb deletion, including MAP2K6 and mapping 1.28?Mb upstream to SOX9, identified in a patient with Pierre Robin sequence and osteopenia with multiple fractures. Am J Med Genet A. 2015 Aug; 167A(8):1842-50.Am J Med Genet A2015-06-08T00:00:002015A de novo 1.58?Mb deletion, including MAP2K6 and mapping 1.28?Mb upstream to SOX9, identified in a patient with Pierre Robin sequence and osteopenia with multiple fractures.26085809Dharmadhikari AV, Szafranski P, Kalinichenko VV, Stankiewicz PCurrent genomicsGenomic and Epigenetic Complexity of the FOXF1 Locus in 16q24.1: Implications for Development and Disease. Curr Genomics. 2015 Apr; 16(2):107-16.Curr Genomics2015-04-01T00:00:002015Genomic and Epigenetic Complexity of the FOXF1 Locus in 16q24.1: Implications for Development and Disease.74Professor10Assistant Professor54Instructor21Chair14Associate Professor12609595Huang JH, Rajkovic A, Szafranski P, Ochsner S, Richards J, Goode SGene expression patterns : GEPExpression of Drosophila neoplastic tumor suppressor genes discslarge, scribble, and lethal giant larvae in the mammalian ovary. Gene Expr Patterns. 2003 Mar; 3(1):3-11.Gene Expr Patterns2003-03-01T00:00:002003Expression of Drosophila neoplastic tumor suppressor genes discslarge, scribble, and lethal giant larvae in the mammalian ovary.Medicine-Epidemiology & Populat SciAuthorship 3203074Authorship 321775126703872Prothro SL, Plosa E, Markham M, Szafranski P, Stankiewicz P, Killen SAThe Journal of pediatricsPrenatal Diagnosis of Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins. J Pediatr. 2016 Mar; 170:317-8.J Pediatr2015-12-17T00:00:002015Prenatal Diagnosis of Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins.27071622Szafranski P, Gambin T, Dharmadhikari AV, Akdemir KC, Jhangiani SN, Schuette J, Godiwala N, Yatsenko SA, Sebastian J, Madan-Khetarpal S, Surti U, Abellar RG, Bateman DA, Wilson AL, Markham MH, Slamon J, Santos-Simarro F, Palomares M, Nevado J, Lapunzina P, Chung BH, Wong WL, Chu YWY, Mok GTK, Kerem E, Reiter J, Ambalavanan N, Anderson SA, Kelly DR, Shieh J, Rosenthal TC, Scheible K, Steiner L, Iqbal MA, McKinnon ML, Hamilton SJ, Schlade-Bartusiak K, English D, Hendson G, Roeder ER, DeNapoli TS, Littlejohn RO, Wolff DJ, Wagner CL, Yeung A, Francis D, Fiorino EK, Edelman M, Fox J, Hayes DA, Janssens S, De Baere E, Menten B, Loccufier A, Vanwalleghem L, Moerman P, Sznajer Y, Lay AS, Kussmann JL, Chawla J, Payton DJ, Phillips GE, Brosens E, Tibboel D, de Klein A, Maystadt I, Fisher R, Sebire N, Male A, Chopra M, Pinner J, Malcolm G, Peters G, Arbuckle S, Lees M, Mead Z, Quarrell O, Sayers R, Owens M, Shaw-Smith C, Lioy J, McKay E, de Leeuw N, Feenstra I, Spruijt L, Elmslie F, Thiruchelvam T, Bacino CA, Langston C, Lupski JR, Sen P, Popek E, Stankiewicz PHuman geneticsPathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veins. Hum Genet. 2016 May; 135(5):569-586.Hum Genet2016-04-12T00:00:002016Pathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veins.Authorship 3248501Authorship 325117227145217Reiter J, Szafranski P, Breuer O, Perles Z, Dagan T, Stankiewicz P, Kerem EPediatric pulmonologyVariable phenotypic presentation of a novel FOXF1 missense mutation in a single family. Pediatr Pulmonol. 2016 09; 51(9):921-7.Pediatr Pulmonol2016-05-04T00:00:002016Variable phenotypic presentation of a novel FOXF1 missense mutation in a single family.27374786Szafranski P, Coban-Akdemir ZH, Rupps R, Grazioli S, Wensley D, Jhangiani SN, Popek E, Lee AF, Lupski JR, Boerkoel CF, Stankiewicz PAmerican journal of medical genetics. Part APhenotypic expansion of TBX4 mutations to include acinar dysplasia of the lungs. Am J Med Genet A. 2016 09; 170(9):2440-4.Am J Med Genet A2016-07-04T00:00:002016Phenotypic expansion of TBX4 mutations to include acinar dysplasia of the lungs.18184654Wu L, Yong SL, Fan C, Ni Y, Yoo S, Zhang T, Zhang X, Obejero-Paz CA, Rho HJ, Ke T, Szafranski P, Jones SW, Chen Q, Wang QKThe Journal of biological chemistryIdentification of a new co-factor, MOG1, required for the full function of cardiac sodium channel Nav 1.5. J Biol Chem. 2008 Mar 14; 283(11):6968-78.J Biol Chem2008-01-09T00:00:002008Identification of a new co-factor, MOG1, required for the full function of cardiac sodium channel Nav 1.5.14961121Tian XL, Kadaba R, You SA, Liu M, Timur AA, Yang L, Chen Q, Szafranski P, Rao S, Wu L, Housman DE, DiCorleto PE, Driscoll DJ, Borrow J, Wang QNatureIdentification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome. Nature. 2004 Feb 12; 427(6975):640-5.Nature2004-02-12T00:00:002004Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome.15056617Szafranski P, Goode SDevelopment (Cambridge, England)A Fasciclin 2 morphogenetic switch organizes epithelial cell cluster polarity and motility. Development. 2004 May; 131(9):2023-36.Development2004-03-31T00:00:002004A Fasciclin 2 morphogenetic switch organizes epithelial cell cluster polarity and motility.One Baylor PlazaHouston, 77030TX17103414Szafranski P, Goode SDevelopmental dynamics : an official publication of the American Association of AnatomistsBasolateral junctions are sufficient to suppress epithelial invasion during Drosophila oogenesis. Dev Dyn. 2007 Feb; 236(2):364-73.Dev Dyn2007-02-01T00:00:002007Basolateral junctions are sufficient to suppress epithelial invasion during Drosophila oogenesis.18430928Zhao M, Szafranski P, Hall CA, Goode SGeneticsBasolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cells. Genetics. 2008 Apr; 178(4):1947-71.Genetics2008-04-01T00:00:002008Basolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cells.19565676Szafranski PMitochondrial DNAThe mitochondrial trn-cox1 locus: rapid evolution in Pompilidae and evidence of bias in cox1 initiation and termination codon usage. Mitochondrial DNA. 2009 Feb; 20(1):15-25.Mitochondrial DNA2009-02-01T00:00:002009The mitochondrial trn-cox1 locus: rapid evolution in Pompilidae and evidence of bias in cox1 initiation and termination codon usage.Authorship 6532508Authorship 654052227638768Dharmadhikari AV, Sun JJ, Gogolewski K, Carofino BL, Ustiyan V, Hill M, Majewski T, Szafranski P, Justice MJ, Ray RS, Dickinson ME, Kalinichenko VV, Gambin A, Stankiewicz PBiology openLethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression. Biol Open. 2016 Nov 15; 5(11):1595-1606.Biol Open2016-11-15T00:00:002016Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression.27880765Gu S, Szafranski P, Akdemir ZC, Yuan B, Cooper ML, Magri?? MA, Bacino CA, Lalani SR, Breman AM, Smith JL, Patel A, Song RH, Bi W, Cheung SW, Carvalho CM, Stankiewicz P, Lupski JRPLoS geneticsMechanisms for Complex Chromosomal Insertions. PLoS Genet. 2016 Nov; 12(11):e1006446.PLoS Genet2016-11-23T00:00:002016Mechanisms for Complex Chromosomal Insertions.Authorship 678167327772553Macias A, Gambin T, Szafranski P, Jhangiani SN, Kolasa A, Obersztyn E, Lupski JR, Stankiewicz P, Kaminska ANeurologia i neurochirurgia polskaCAV3 mutation in a patient with transient hyperCKemia and myalgia. Neurol Neurochir Pol. 2016 Nov - Dec; 50(6):468-473.Neurol Neurochir Pol2016-07-09T00:00:002016CAV3 mutation in a patient with transient hyperCKemia and myalgia.20506139Szafranski P, Schaaf CP, Person RE, Gibson IB, Xia Z, Mahadevan S, Wiszniewska J, Bacino CA, Lalani S, Potocki L, Kang SH, Patel A, Cheung SW, Probst FJ, Graham BH, Shinawi M, Beaudet AL, Stankiewicz PHuman mutationStructures and molecular mechanisms for common 15q13.3 microduplications involving CHRNA7: benign or pathological? Hum Mutat. 2010 Jul; 31(7):840-50.Hum Mutat2010-07-01T00:00:002010Structures and molecular mechanisms for common 15q13.3 microduplications involving CHRNA7: benign or pathological?21205869Ou Z, Stankiewicz P, Xia Z, Breman AM, Dawson B, Wiszniewska J, Szafranski P, Cooper ML, Rao M, Shao L, South ST, Coleman K, Fernhoff PM, Deray MJ, Rosengren S, Roeder ER, Enciso VB, Chinault AC, Patel A, Kang SH, Shaw CA, Lupski JR, Cheung SWGenome researchObservation and prediction of recurrent human translocations mediated by NAHR between nonhomologous chromosomes. Genome Res. 2011 Jan; 21(1):33-46.Genome Res2011-01-01T00:00:002011Observation and prediction of recurrent human translocations mediated by NAHR between nonhomologous chromosomes.22543972Dharmadhikari AV, Kang SH, Szafranski P, Person RE, Sampath S, Prakash SK, Bader PI, Phillips JA, Hannig V, Williams M, Vinson SS, Wilfong AA, Reimschisel TE, Craigen WJ, Patel A, Bi W, Lupski JR, Belmont J, Cheung SW, Stankiewicz PHuman molecular geneticsSmall rare recurrent deletions and reciprocal duplications in 2q21.1, including brain-specific ARHGEF4 and GPR148. Hum Mol Genet. 2012 Aug 01; 21(15):3345-55.Hum Mol Genet2012-04-27T00:00:002012Small rare recurrent deletions and reciprocal duplications in 2q21.1, including brain-specific ARHGEF4 and GPR148.Authorship 785437127822317Szafranski P, Herrera C, Proe LA, Coffman B, Kearney DL, Popek E, Stankiewicz PClinical epigeneticsNarrowing the FOXF1 distant enhancer region on 16q24.1 critical for ACDMPV. Clin Epigenetics. 2016; 8:112.Clin Epigenetics2016-11-03T00:00:002016Narrowing the FOXF1 distant enhancer region on 16q24.1 critical for ACDMPV.23505205Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz PHuman mutationNovel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. Hum Mutat. 2013 Jun; 34(6):801-11.Hum Mutat2013-04-12T00:00:002013Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain.28251352Zhang J, Gambin T, Yuan B, Szafranski P, Rosenfeld JA, Balwi MA, Alswaid A, Al-Gazali L, Shamsi AMA, Komara M, Ali BR, Roeder E, McAuley L, Roy DS, Manchester DK, Magoulas P, King LE, Hannig V, Bonneau D, Denomm?-Pichon AS, Charif M, Besnard T, B?zieau S, Cogn? B, Andrieux J, Zhu W, He W, Vetrini F, Ward PA, Cheung SW, Bi W, Eng CM, Lupski JR, Yang Y, Patel A, Lalani SR, Xia F, Stankiewicz PHuman geneticsHaploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features. Hum Genet. 2017 04; 136(4):377-386.Hum Genet2017-03-01T00:00:002017Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features.Authorship 8404254Authorship 868635128359330Szafranski PBMC genomicsEvolutionarily recent, insertional fission of mitochondrial cox2 into complementary genes in bilaterian Metazoa. BMC Genomics. 2017 03 31; 18(1):269.BMC Genomics2017-03-31T00:00:002017Evolutionarily recent, insertional fission of mitochondrial cox2 into complementary genes in bilaterian Metazoa.Authorship 869050128405742Szafranski P, Karolak JA, Lanza D, Gajecka M, Heaney J, Stankiewicz PMammalian genome : official journal of the International Mammalian Genome SocietyCRISPR/Cas9-mediated deletion of lncRNA Gm26878 in the distant Foxf1 enhancer region. Mamm Genome. 2017 Aug; 28(7-8):275-282.Mamm Genome2017-04-12T00:00:002017CRISPR/Cas9-mediated deletion of lncRNA Gm26878 in the distant Foxf1 enhancer region.Authorship 873513428660352Zhang J, Gambin T, Yuan B, Szafranski P, Rosenfeld JA, Balwi MA, Alswaid A, Al-Gazali L, Shamsi AMA, Komara M, Ali BR, Roeder E, McAuley L, Roy DS, Manchester DK, Magoulas P, King LE, Hannig V, Bonneau D, Denomm?-Pichon AS, Charif M, Besnard T, B?zieau S, Cogn? B, Andrieux J, Zhu W, He W, Vetrini F, Ward PA, Cheung SW, Bi W, Eng CM, Lupski JR, Yang Y, Patel A, Lalani SR, Xia F, Stankiewicz PHuman geneticsErratum to: Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features. Hum Genet. 2017 08; 136(8):1009-1011.Hum Genet2017-08-01T00:00:002017Erratum to: Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features.Authorship 105895121109226Ramocki MB, Bartnik M, Szafranski P, Kolodziejska KE, Xia Z, Bravo J, Miller GS, Rodriguez DL, Williams CA, Bader PI, Szczepanik E, Mazurczak T, Antczak-Marach D, Coldwell JG, Akman CI, McAlmon K, Cohen MP, McGrath J, Roeder E, Mueller J, Kang SH, Bacino CA, Patel A, Bocian E, Shaw CA, Cheung SW, Mazurczak T, Stankiewicz PAmerican journal of human geneticsRecurrent distal 7q11.23 deletion including HIP1 and YWHAG identified in patients with intellectual disabilities, epilepsy, and neurobehavioral problems. Am J Hum Genet. 2010 Dec 10; 87(6):857-65.Am J Hum Genet2010-11-25T00:00:002010Recurrent distal 7q11.23 deletion including HIP1 and YWHAG identified in patients with intellectual disabilities, epilepsy, and neurobehavioral problems.22929023Lalani SR, Shaw C, Wang X, Patel A, Patterson LW, Kolodziejska K, Szafranski P, Ou Z, Tian Q, Kang SH, Jinnah A, Ali S, Malik A, Hixson P, Potocki L, Lupski JR, Stankiewicz P, Bacino CA, Dawson B, Beaudet AL, Boricha FM, Whittaker R, Li C, Ware SM, Cheung SW, Penny DJ, Jefferies JL, Belmont JWEuropean journal of human genetics : EJHGRare DNA copy number variants in cardiovascular malformations with extracardiac abnormalities. Eur J Hum Genet. 2013 Feb; 21(2):173-81.Eur J Hum Genet2012-08-29T00:00:002012Rare DNA copy number variants in cardiovascular malformations with extracardiac abnormalities.23034409Szafranski P, Dharmadhikari AV, Brosens E, Gurha P, Kolodziejska KE, Zhishuo O, Dittwald P, Majewski T, Mohan KN, Chen B, Person RE, Tibboel D, de Klein A, Pinner J, Chopra M, Malcolm G, Peters G, Arbuckle S, Guiang SF, Hustead VA, Jessurun J, Hirsch R, Witte DP, Maystadt I, Sebire N, Fisher R, Langston C, Sen P, Stankiewicz PGenome researchSmall noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder. Genome Res. 2013 Jan; 23(1):23-33.Genome Res2012-10-03T00:00:002012Small noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder.Authorship 8790281Authorship 8794563Authorship 883419828942966Stankiewicz P, Khan TN, Szafranski P, Slattery L, Streff H, Vetrini F, Bernstein JA, Brown CW, Rosenfeld JA, Rednam S, Scollon S, Bergstrom KL, Parsons DW, Plon SE, Vieira MW, Quaio CRDC, Baratela WAR, Acosta Guio JC, Armstrong R, Mehta SG, Rump P, Pfundt R, Lewandowski R, Fernandes EM, Shinde DN, Tang S, Hoyer J, Zweier C, Reis A, Bacino CA, Xiao R, Breman AM, Smith JL, Deciphering Developmental Disorders Study, Katsanis N, Bostwick B, Popp B, Davis EE, Yang YAmerican journal of human geneticsHaploinsufficiency of the Chromatin Remodeler BPTF Causes Syndromic Developmental and Speech Delay, Postnatal Microcephaly, and Dysmorphic Features. Am J Hum Genet. 2017 Oct 05; 101(4):503-515.Am J Hum Genet2017-09-21T00:00:002017Haploinsufficiency of the Chromatin Remodeler BPTF Causes Syndromic Developmental and Speech Delay, Postnatal Microcephaly, and Dysmorphic Features.28984842Szafranski PGenesIntercompartmental Piecewise Gene Transfer. Genes (Basel). 2017 Oct 06; 8(10).Genes (Basel)2017-10-06T00:00:002017Intercompartmental Piecewise Gene Transfer.29198536Towe CT, White FV, Grady RM, Sweet SC, Eghtesady P, Wegner DJ, Sen P, Szafranski P, Stankiewicz P, Hamvas A, Cole FS, Wambach JAThe Journal of pediatricsInfants with Atypical Presentations of Alveolar Capillary Dysplasia with Misalignment of the Pulmonary Veins Who Underwent Bilateral Lung Transplantation. J Pediatr. 2018 03; 194:158-164.e1.J Pediatr2017-12-01T00:00:002017Infants with Atypical Presentations of Alveolar Capillary Dysplasia with Misalignment of the Pulmonary Veins Who Underwent Bilateral Lung Transplantation.CHRISAMOSCHRIS AMOS13498AMOS, CHRISProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorD010547Disorders32920.887472Persistent Fetal Circulation Syndrome30084155Szafranski P, Kosmider E, Liu Q, Karolak JA, Currie L, Parkash S, Kahler SG, Roeder E, Littlejohn RO, DeNapoli TS, Shardonofsky FR, Henderson C, Powers G, Poisson V, B?rub? D, Oligny L, Michaud JL, Janssens S, De Coen K, Van Dorpe J, Dheedene A, Harting MT, Weaver MD, Khan AM, Tatevian N, Wambach J, Gibbs KA, Popek E, Gambin A, Stankiewicz PHuman mutationLINE- and Alu-containing genomic instability hotspot at 16q24.1 associated with recurrent and nonrecurrent CNV deletions causative for ACDMPV. Hum Mutat. 2018 12; 39(12):1916-1925.Hum Mutat2018-08-22T00:00:002018LINE- and Alu-containing genomic instability hotspot at 16q24.1 associated with recurrent and nonrecurrent CNV deletions causative for ACDMPV.D051858Chemicals & Drugs3557770.693017Forkhead Transcription FactorsD004742Chemicals & Drugs2574680.812404Enhancer Elements, GeneticAuthorship 9342631Authorship 938328230632303Salehi Karlsl?tt K, Pettersson M, J?ntti N, Szafranski P, Wester T, Husberg B, Ullberg U, Stankiewicz P, Nordgren A, Lundin J, Lindstrand A, Nordenskj?ld AMolecular genetics & genomic medicineRare copy number variants contribute pathogenic alleles in patients with intestinal malrotation. Mol Genet Genomic Med. 2019 03; 7(3):e549.Mol Genet Genomic Med2019-01-10T00:00:002019Rare copy number variants contribute pathogenic alleles in patients with intestinal malrotation.D017384Disorders4238750.769194Sequence DeletionDepartment of MedicineDepartment of Molecular & Human GeneticsMolecular & Human GeneticsBaylor College of MedicineCARLOSBACINOCARLOS BACINO29.70508570000000-95.401808700000002643BACINO, CARLOSProfessorBRENDANLEEBRENDAN LEE0.000000000000000.000000000000002022LEE, BRENDANProfessorJAMESLUPSKIJAMES LUPSKI29.71073630000000-95.396604500000003140LUPSKI, JAMESProfessorALEKSANDARMILOSAVLJEVICALEKSANDAR MILOSAVLJEVIC0.000000000000000.00000000000000337MILOSAVLJEVIC, ALEKSANDARProfessorSAU WAICHEUNGSAU WAI CHEUNG29.69822590000000-95.35731940000000499CHEUNG, SAU WAIProfessorPAWELSTANKIEWICZPAWEL STANKIEWICZ29.71073630000000-95.39660450000000166STANKIEWICZ, PAWELProfessorAuthorship 9406394930639323Karolak JA, Vincent M, Deutsch G, Gambin T, Cogn? B, Pichon O, Vetrini F, Mefford HC, Dines JN, Golden-Grant K, Dipple K, Freed AS, Leppig KA, Dishop M, Mowat D, Bennetts B, Gifford AJ, Weber MA, Lee AF, Boerkoel CF, Bartell TM, Ward-Melver C, Besnard T, Petit F, Bache I, T?mer Z, Denis-Musquer M, Joubert M, Martinovic J, B?n?teau C, Molin A, Carles D, Andr? G, Bieth E, Chassaing N, Devisme L, Chalabreysse L, Pasquier L, Secq V, Don M, Orsaria M, Missirian C, Mortreux J, Sanlaville D, Pons L, K?ry S, B?zieau S, Liet JM, Joram N, Bihou?e T, Scott DA, Brown CW, Scaglia F, Tsai AC, Grange DK, Phillips JA, Pfotenhauer JP, Jhangiani SN, Gonzaga-Jauregui CG, Chung WK, Schauer GM, Lipson MH, Mercer CL, van Haeringen A, Liu Q, Popek E, Coban Akdemir ZH, Lupski JR, Szafranski P, Isidor B, Le Caignec C, Stankiewicz PAmerican journal of human geneticsComplex Compound Inheritance of Lethal Lung Developmental Disorders Due to Disruption of the TBX-FGF Pathway. Am J Hum Genet. 2019 02 07; 104(2):213-228.Am J Hum Genet2019-01-10T00:00:002019Complex Compound Inheritance of Lethal Lung Developmental Disorders Due to Disruption of the TBX-FGF Pathway.SEEMALALANISEEMA LALANI29.71306600000000-95.39705500000000391LALANI, SEEMAProfessor7.550020.00458063327research areas14.11810.014507644coauthor of202.49410.744460similar to1168selected publicationsAuthorship 944417230961659Schulze KV, Szafranski P, Lesmana H, Hopkin RJ, Hamvas A, Wambach JA, Shinawi M, Zapata G, Carvalho CMB, Liu Q, Karolak JA, Lupski JR, Hanchard NA, Stankiewicz PClinical epigeneticsNovel parent-of-origin-specific differentially methylated loci on chromosome 16. Clin Epigenetics. 2019 04 08; 11(1):60.Clin Epigenetics2019-04-08T00:00:002019Novel parent-of-origin-specific differentially methylated loci on chromosome 16.Authorship 1260363D062085Chemicals & Drugs2725980.648717RNA, Long NoncodingAuthorship 1277201Authorship 128621123486542Witsch J, Szafranski P, Chen CA, Immken L, Simpson Patel G, Hixson P, Cheung SW, Stankiewicz P, Schaaf CPEuropean journal of human genetics : EJHGIntragenic deletions of the IGF1 receptor gene in five individuals with psychiatric phenotypes and developmental delay. Eur J Hum Genet. 2013 Nov; 21(11):1304-7.Eur J Hum Genet2013-03-13T00:00:002013Intragenic deletions of the IGF1 receptor gene in five individuals with psychiatric phenotypes and developmental delay.23657883Dittwald P, Gambin T, Szafranski P, Li J, Amato S, Divon MY, Rodr?guez Rojas LX, Elton LE, Scott DA, Schaaf CP, Torres-Martinez W, Stevens AK, Rosenfeld JA, Agadi S, Francis D, Kang SH, Breman A, Lalani SR, Bacino CA, Bi W, Milosavljevic A, Beaudet AL, Patel A, Shaw CA, Lupski JR, Gambin A, Cheung SW, Stankiewicz PGenome researchNAHR-mediated copy-number variants in a clinical population: mechanistic insights into both genomic disorders and Mendelizing traits. Genome Res. 2013 Sep; 23(9):1395-409.Genome Res2013-05-08T00:00:002013NAHR-mediated copy-number variants in a clinical population: mechanistic insights into both genomic disorders and Mendelizing traits.23943206Szafranski P, Yang Y, Nelson MU, Bizzarro MJ, Morotti RA, Langston C, Stankiewicz PHuman mutationNovel FOXF1 deep intronic deletion causes lethal lung developmental disorder, alveolar capillary dysplasia with misalignment of pulmonary veins. Hum Mutat. 2013 Nov; 34(11):1467-71.Hum Mutat2013-09-04T00:00:002013Novel FOXF1 deep intronic deletion causes lethal lung developmental disorder, alveolar capillary dysplasia with misalignment of pulmonary veins.Authorship 9490127Authorship 9491211131189067Vincent M, Karolak JA, Deutsch G, Gambin T, Popek E, Isidor B, Szafranski P, Le Caignec C, Stankiewicz PAmerican journal of respiratory and critical care medicineClinical, Histopathological, and Molecular Diagnostics in Lethal Lung Developmental Disorders. Am J Respir Crit Care Med. 2019 11 01; 200(9):1093-1101.Am J Respir Crit Care Med2019-11-01T00:00:002019Clinical, Histopathological, and Molecular Diagnostics in Lethal Lung Developmental Disorders.31199666Pradhan A, Dunn A, Ustiyan V, Bolte C, Wang G, Whitsett JA, Zhang Y, Porollo A, Hu YC, Xiao R, Szafranski P, Shi D, Stankiewicz P, Kalin TV, Kalinichenko VVAmerican journal of respiratory and critical care medicineThe S52F FOXF1 Mutation Inhibits STAT3 Signaling and Causes Alveolar Capillary Dysplasia. Am J Respir Crit Care Med. 2019 10 15; 200(8):1045-1056.Am J Respir Crit Care Med2019-10-15T00:00:002019The S52F FOXF1 Mutation Inhibits STAT3 Signaling and Causes Alveolar Capillary Dysplasia.Authorship 952070231309540Karolak JA, Szafranski P, Kilner D, Patel C, Scurry B, Kinning E, Chandler K, Jhangiani SN, Coban Akdemir ZH, Lupski JR, Popek E, Stankiewicz PClinical geneticsHeterozygous CTNNB1 and TBX4 variants in a patient with abnormal lung growth, pulmonary hypertension, microcephaly, and spasticity. Clin Genet. 2019 10; 96(4):366-370.Clin Genet2019-07-22T00:00:002019Heterozygous CTNNB1 and TBX4 variants in a patient with abnormal lung growth, pulmonary hypertension, microcephaly, and spasticity.Authorship 9542651331436901Karolak JA, Bacolla A, Liu Q, Lantz PE, Petty J, Trapane P, Panzer K, Totapally BR, Niu Z, Xiao R, Xie NG, Wu LR, Szafranski P, Zhang DY, Stankiewicz PAmerican journal of medical genetics. Part AA recurrent 8 bp frameshifting indel in FOXF1 defines a novel mutation hotspot associated with alveolar capillary dysplasia with misalignment of pulmonary veins. Am J Med Genet A. 2019 11; 179(11):2272-2276.Am J Med Genet A2019-08-22T00:00:002019A recurrent 8 bp frameshifting indel in FOXF1 defines a novel mutation hotspot associated with alveolar capillary dysplasia with misalignment of pulmonary veins.Authorship 958074631662342Steiner LA, Getman M, Schiralli Lester GM, Iqbal MA, Katzman P, Szafranski P, Stankiewicz P, Bhattacharya S, Mariani T, Pryhuber G, Lin X, Young JL, Dean DA, Scheible KJournal of medical geneticsDisruption of normal patterns of FOXF1 expression in a lethal disorder of lung development. J Med Genet. 2020 05; 57(5):296-300.J Med Genet2019-10-29T00:00:002019Disruption of normal patterns of FOXF1 expression in a lethal disorder of lung development.true1Associate ProfessorAssociate Professortrue1InstructorInstructortrue1ProfessorProfessorAuthorship 960529131686214Szafranski P, Liu Q, Karolak JA, Song X, de Leeuw N, Faas B, Gerychova R, Janku P, Jezova M, Valaskova I, Gibbs KA, Surrey LF, Poisson V, B?rub? D, Oligny LL, Michaud JL, Popek E, Stankiewicz PHuman geneticsAssociation of rare non-coding SNVs in the lung-specific FOXF1 enhancer with a mitigation of the lethal ACDMPV phenotype. Hum Genet. 2019 Dec; 138(11-12):1301-1311.Hum Genet2019-11-04T00:00:002019Association of rare non-coding SNVs in the lung-specific FOXF1 enhancer with a mitigation of the lethal ACDMPV phenotype.Authorship 9777101632036090Karolak JA, Liu Q, Xie NG, Wu LR, Rocha G, Fernandes S, Ho-Ming L, Lo IF, Mowat D, Fiorino EK, Edelman M, Fox J, Hayes DA, Witte D, Parrott A, Popek E, Szafranski P, Zhang DY, Stankiewicz PThe Journal of molecular diagnostics : JMDHighly Sensitive Blocker Displacement Amplification and Droplet Digital PCR Reveal Low-Level Parental FOXF1 Somatic Mosaicism in Families with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins. J Mol Diagn. 2020 04; 22(4):447-456.J Mol Diagn2020-02-07T00:00:002020Highly Sensitive Blocker Displacement Amplification and Droplet Digital PCR Reveal Low-Level Parental FOXF1 Somatic Mosaicism in Families with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins.JUNHYOUNGPARKJUNHYOUNG PARK0.000000000000000.000000000000006530PARK, JUNHYOUNGInstructorMARIADE HAROMARIA DE HARO0.000000000000000.000000000000005746DE HARO, MARIAInstructorOLGADUDCHENKOOLGA DUDCHENKO0.000000000000000.000000000000006786DUDCHENKO, OLGAAssistant Professortrue1InstructorInstructortrue1ProfessorProfessorAuthorship 1009305333478486Karolak JA, Gambin T, Szafranski P, Stankiewicz PRespiratory researchPotential interactions between the TBX4-FGF10 and SHH-FOXF1 signaling during human lung development revealed using ChIP-seq. Respir Res. 2021 Jan 21; 22(1):26.Respir Res2021-01-21T00:00:002021Potential interactions between the TBX4-FGF10 and SHH-FOXF1 signaling during human lung development revealed using ChIP-seq.Authorship 1010111133513839Szafranski P, Stankiewicz PGenesLong Non-Coding RNA FENDRR: Gene Structure, Expression, and Biological Relevance. Genes (Basel). 2021 01 27; 12(2).Genes (Basel)2021-01-27T00:00:002021Long Non-Coding RNA FENDRR: Gene Structure, Expression, and Biological Relevance.Authorship 1014088133739555Szafranski P, Gambin T, Karolak JA, Popek E, Stankiewicz PHuman mutationLung-specific distant enhancer cis regulates expression of FOXF1 and lncRNA FENDRR. Hum Mutat. 2021 06; 42(6):694-698.Hum Mutat2021-04-06T00:00:002021Lung-specific distant enhancer cis regulates expression of FOXF1 and lncRNA FENDRR.Authorship 1026296334315444Karolak JA, Gambin T, Szafranski P, Maywald RL, Popek E, Heaney JD, Stankiewicz PRespiratory researchPerturbation of semaphorin and VEGF signaling in ACDMPV lungs due to FOXF1 deficiency. Respir Res. 2021 Jul 27; 22(1):212.Respir Res2021-07-27T00:00:002021Perturbation of semaphorin and VEGF signaling in ACDMPV lungs due to FOXF1 deficiency.Authorship 1040491235075769Yildiz B?l?kbasi E, Karolak JA, Szafranski P, Gambin T, Murik O, Zeevi DA, Altarescu G, Stankiewicz PAmerican journal of medical genetics. Part AExacerbation of mild lung disorders to lethal pulmonary hypoplasia by a noncoding hypomorphic SNV in a lung-specific enhancer in trans to the frameshifting TBX4 variant. Am J Med Genet A. 2022 05; 188(5):1420-1425.Am J Med Genet A2022-01-25T00:00:002022Exacerbation of mild lung disorders to lethal pulmonary hypoplasia by a noncoding hypomorphic SNV in a lung-specific enhancer in trans to the frameshifting TBX4 variant.Authorship 137982224254229Smyk M, Szafranski P, Startek M, Gambin A, Stankiewicz PChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biologyChromosome conformation capture-on-chip analysis of long-range cis-interactions of the SOX9 promoter. Chromosome Res. 2013 Dec; 21(8):781-8.Chromosome Res2013-11-20T00:00:002013Chromosome conformation capture-on-chip analysis of long-range cis-interactions of the SOX9 promoter.Authorship 1045686335533956Yildiz B?l?kbasi E, Karolak JA, Gambin T, Szafranski P, Deutsch GH, Stankiewicz PEuropean journal of medical geneticsDo paternal deletions involving the FOXF1 locus on chromosome 16q24.1 manifest with more severe non-lung anomalies? Eur J Med Genet. 2022 Jun; 65(6):104519.Eur J Med Genet2022-05-06T00:00:002022Do paternal deletions involving the FOXF1 locus on chromosome 16q24.1 manifest with more severe non-lung anomalies?Authorship 1047017435648090Karolak JA, Deutsch G, Gambin T, Szafranski P, Popek E, Stankiewicz PAmerican journal of respiratory cell and molecular biologyTranscriptome and Immunohistochemical Analyses in TBX4- and FGF10-Deficient Lungs Imply TMEM100 as a Mediator of Human Lung Development. Am J Respir Cell Mol Biol. 2022 06; 66(6):694-697.Am J Respir Cell Mol Biol2022-06-01T00:00:002022Transcriptome and Immunohistochemical Analyses in TBX4- and FGF10-Deficient Lungs Imply TMEM100 as a Mediator of Human Lung Development.Authorship 1051218235902696Yildiz B?l?kbasi E, Karolak JA, Szafranski P, Gambin T, Matsika A, McManus S, Scott HS, Arts P, Ha T, Barnett CP, Rodgers J, Stankiewicz PEuropean journal of human genetics : EJHGVariable expressivity in a four-generation ACDMPV family with a non-coding hypermorphic SNV in trans to the frameshifting FOXF1 variant. Eur J Hum Genet. 2022 10; 30(10):1182-1186.Eur J Hum Genet2022-07-28T00:00:002022Variable expressivity in a four-generation ACDMPV family with a non-coding hypermorphic SNV in trans to the frameshifting FOXF1 variant.Authorship 10592581Authorship 1058914336124617Yildiz B?l?kbasi E, Karolak JA, Szafranski P, Gambin T, Willard N, Abman SH, Galambos C, Kinsella JP, Stankiewicz PMolecular genetics & genomic medicineHigh-level gonosomal mosaicism for a pathogenic non-coding CNV deletion of the lung-specific FOXF1 enhancer in an unaffected mother of an infant with ACDMPV. Mol Genet Genomic Med. 2022 Nov; 10(11):e2062.Mol Genet Genomic Med2022-09-20T00:00:002022High-level gonosomal mosaicism for a pathogenic non-coding CNV deletion of the lung-specific FOXF1 enhancer in an unaffected mother of an infant with ACDMPV.36157490Szafranski P, Majewski T, Yildiz B?l?kbasi E, Gambin T, Karolak JA, Cortes-Santiago N, Bruckner M, Amann G, Weis D, Stankiewicz PGenes & diseasesUltra-conserved non-coding sequences within the FOXF1 enhancer are critical for human lung development. Genes Dis. 2022 Nov; 9(6):1423-1426.Genes Dis2022-05-18T00:00:002022Ultra-conserved non-coding sequences within the FOXF1 enhancer are critical for human lung development.Authorship 1063332136732536Szafranski PScientific reportsNew Dielis species and structural dichotomy of the mitochondrial cox2 gene in Scoliidae wasps. Sci Rep. 2023 02 02; 13(1):1950.Sci Rep2023-02-02T00:00:002023New Dielis species and structural dichotomy of the mitochondrial cox2 gene in Scoliidae wasps.true1Assistant ProfessorAssistant ProfessorAuthorship 1218061Authorship 180423Authorship 1074543437401868Galambos C, Logan JW, Stankiewicz P, Szafranski P, Zalles C, Gonzales J, Nath S, Patel S, Abman SHPediatric pulmonologyHistologic features and decreased lung FOXF1 gene expression in severe bronchopulmonary dysplasia without a genetic diagnosis of alveolar capillary dysplasia. Pediatr Pulmonol. 2023 10; 58(10):2746-2749.Pediatr Pulmonol2023-07-04T00:00:002023Histologic features and decreased lung FOXF1 gene expression in severe bronchopulmonary dysplasia without a genetic diagnosis of alveolar capillary dysplasia.Authorship 10829041Authorship 1082858137865798Szafranski P, Garimella RP, Mani H, Hartman R, Deutsch G, Silk A, Benheim A, Stankiewicz PClinical epigeneticsFurther refinement of the differentially methylated distant lung-specific FOXF1 enhancer in a neonate with alveolar capillary dysplasia. Clin Epigenetics. 2023 10 21; 15(1):169.Clin Epigenetics2023-10-21T00:00:002023Further refinement of the differentially methylated distant lung-specific FOXF1 enhancer in a neonate with alveolar capillary dysplasia.37888207Szafranski P, Stankiewicz PNon-coding RNAA Small De Novo CNV Deletion of the Paternal Copy of FOXF1, Leaving lncRNA FENDRR Intact, Provides Insight into Their Bidirectional Promoter Region. Noncoding RNA. 2023 Oct 09; 9(5).Noncoding RNA2023-10-09T00:00:002023A Small De Novo CNV Deletion of the Paternal Copy of FOXF1, Leaving lncRNA FENDRR Intact, Provides Insight into Their Bidirectional Promoter Region.Authorship 1084512138044468Szafranski P, Patrizi S, Gambin T, Afzal B, Schlotterbeck E, Karolak JA, Deutsch G, Roberts D, Stankiewicz PPediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology SocietyDiminished TMEM100 Expression in a Newborn With Acinar Dysplasia and a Novel TBX4 Variant: A Case Report. Pediatr Dev Pathol. 2023 Dec 03; 10935266231213464.Pediatr Dev Pathol2023-12-03T00:00:002023Diminished TMEM100 Expression in a Newborn With Acinar Dysplasia and a Novel TBX4 Variant: A Case Report.true1ProfessorProfessorAuthorship 284123Authorship 1432651324722050Sen P, Dharmadhikari AV, Majewski T, Mohammad MA, Kalin TV, Zabielska J, Ren X, Bray M, Brown HM, Welty S, Thevananther S, Langston C, Szafranski P, Justice MJ, Kalinichenko VV, Gambin A, Belmont J, Stankiewicz PPloS oneComparative analyses of lung transcriptomes in patients with alveolar capillary dysplasia with misalignment of pulmonary veins and in foxf1 heterozygous knockout mice. PLoS One. 2014; 9(4):e94390.PLoS One2014-04-10T00:00:002014Comparative analyses of lung transcriptomes in patients with alveolar capillary dysplasia with misalignment of pulmonary veins and in foxf1 heterozygous knockout mice.Authorship 433645Authorship 459757Authorship 148869124842713Szafranski P, Dharmadhikari AV, Wambach JA, Towe CT, White FV, Grady RM, Eghtesady P, Cole FS, Deutsch G, Sen P, Stankiewicz PAmerican journal of medical genetics. Part ATwo deletions overlapping a distant FOXF1 enhancer unravel the role of lncRNA LINC01081 in etiology of alveolar capillary dysplasia with misalignment of pulmonary veins. Am J Med Genet A. 2014 Aug; 164A(8):2013-9.Am J Med Genet A2014-05-19T00:00:002014Two deletions overlapping a distant FOXF1 enhancer unravel the role of lncRNA LINC01081 in etiology of alveolar capillary dysplasia with misalignment of pulmonary veins.Authorship 149283525087610Campbell IM, Yuan B, Robberecht C, Pfundt R, Szafranski P, McEntagart ME, Nagamani SC, Erez A, Bartnik M, Wisniowiecka-Kowalnik B, Plunkett KS, Pursley AN, Kang SH, Bi W, Lalani SR, Bacino CA, Vast M, Marks K, Patton M, Olofsson P, Patel A, Veltman JA, Cheung SW, Shaw CA, Vissers LE, Vermeesch JR, Lupski JR, Stankiewicz PAmerican journal of human geneticsParental somatic mosaicism is underrecognized and influences recurrence risk of genomic disorders. Am J Hum Genet. 2014 Aug 07; 95(2):173-82.Am J Hum Genet2014-07-31T00:00:002014Parental somatic mosaicism is underrecognized and influences recurrence risk of genomic disorders.Authorship 5973411Authorship 884601Authorship 664251Authorship 690068