Connection

MARGARET GOODELL to DNA Methylation

This is a "connection" page, showing publications MARGARET GOODELL has written about DNA Methylation.
Connection Strength

5.803
  1. The push and pull of DNA methylation. Science. 2021 04 09; 372(6538):128-129.
    View in: PubMed
    Score: 0.436
  2. Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity. Mol Cell. 2020 05 07; 78(3):506-521.e6.
    View in: PubMed
    Score: 0.409
  3. DNA methylation and de-methylation using hybrid site-targeting proteins. Genome Biol. 2018 11 06; 19(1):187.
    View in: PubMed
    Score: 0.369
  4. DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A. Genome Biol. 2017 09 18; 18(1):176.
    View in: PubMed
    Score: 0.341
  5. Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein. Nat Commun. 2017 07 11; 8:16026.
    View in: PubMed
    Score: 0.336
  6. DNMT3A in Leukemia. Cold Spring Harb Perspect Med. 2017 Feb 01; 7(2).
    View in: PubMed
    Score: 0.326
  7. Genome-Wide Analysis of DNA Methylation in Hematopoietic Cells: DNA Methylation Analysis by WGBS. Methods Mol Biol. 2017; 1633:137-149.
    View in: PubMed
    Score: 0.325
  8. DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells. Nat Genet. 2016 09; 48(9):1014-23.
    View in: PubMed
    Score: 0.314
  9. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell. 2016 06 13; 29(6):922-934.
    View in: PubMed
    Score: 0.312
  10. DNMT3A in haematological malignancies. Nat Rev Cancer. 2015 Mar; 15(3):152-65.
    View in: PubMed
    Score: 0.285
  11. Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation. Blood. 2015 Jan 22; 125(4):629-38.
    View in: PubMed
    Score: 0.284
  12. Dynamic DNA methylation discovered during HSC differentiation. Cell Cycle. 2015; 14(5):693-4.
    View in: PubMed
    Score: 0.282
  13. New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells. Exp Hematol. 2014 Aug; 42(8):609-17.
    View in: PubMed
    Score: 0.273
  14. Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet. 2011 Dec 04; 44(1):23-31.
    View in: PubMed
    Score: 0.228
  15. DNMT3A regulates murine megakaryocyte-biased hematopoietic stem cell fate decisions. Blood Adv. 2025 May 13; 9(9):2285-2299.
    View in: PubMed
    Score: 0.145
  16. DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells. Nat Cell Biol. 2023 04; 25(4):528-539.
    View in: PubMed
    Score: 0.125
  17. The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development. Nat Genet. 2022 05; 54(5):625-636.
    View in: PubMed
    Score: 0.118
  18. Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis. Blood. 2020 03 12; 135(11):845-856.
    View in: PubMed
    Score: 0.101
  19. Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons. Elife. 2019 01 15; 8.
    View in: PubMed
    Score: 0.093
  20. Homeobox oncogene activation by pan-cancer DNA hypermethylation. Genome Biol. 2018 08 10; 19(1):108.
    View in: PubMed
    Score: 0.091
  21. DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells. Genome Biol. 2018 07 12; 19(1):88.
    View in: PubMed
    Score: 0.090
  22. Long non-coding RNAs control hematopoietic stem cell function. Cell Stem Cell. 2015 Apr 02; 16(4):426-38.
    View in: PubMed
    Score: 0.072
  23. Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells. Cell Stem Cell. 2014 Sep 04; 15(3):350-364.
    View in: PubMed
    Score: 0.069
  24. MOABS: model based analysis of bisulfite sequencing data. Genome Biol. 2014 Feb 24; 15(2):R38.
    View in: PubMed
    Score: 0.067
  25. Large conserved domains of low DNA methylation maintained by Dnmt3a. Nat Genet. 2014 Jan; 46(1):17-23.
    View in: PubMed
    Score: 0.065
  26. A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells. Blood. 2013 Dec 12; 122(25):4086-9.
    View in: PubMed
    Score: 0.065
  27. Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome. PLoS Genet. 2012; 8(5):e1002692.
    View in: PubMed
    Score: 0.059
  28. TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells. Nat Aging. 2023 Nov; 3(11):1387-1400.
    View in: PubMed
    Score: 0.033
  29. Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL. Cancer Res. 2021 10 01; 81(19):5033-5046.
    View in: PubMed
    Score: 0.028
  30. Mutations in the DNMT3A DNA methyltransferase in acute myeloid leukemia patients cause both loss and gain of function and differential regulation by protein partners. J Biol Chem. 2019 03 29; 294(13):4898-4910.
    View in: PubMed
    Score: 0.023
  31. Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In?Vivo. Cell Rep. 2018 04 03; 23(1):1-10.
    View in: PubMed
    Score: 0.022
  32. Hematopoietic stem cell development: an epigenetic journey. Curr Top Dev Biol. 2014; 107:39-75.
    View in: PubMed
    Score: 0.016
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.