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MARGARET GOODELL to Humans

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This is a "connection" page, showing publications MARGARET GOODELL has written about Humans.
MARGARET GOODELL
Connection Strength
0.954
Humans
  1. Can Ruxolitinib Crash TET2- and IDH2-Driven Clonal Hematopoiesis? Cancer Discov. 2024 Oct 04; 14(10):1768-1770.
    View in: PubMed
    Score: 0.026
  2. Distinct landscape and clinical implications of therapy-related clonal hematopoiesis. J Clin Invest. 2024 Oct 01; 134(19).
    View in: PubMed
    Score: 0.026
  3. SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells. Elife. 2024 Jun 18; 12.
    View in: PubMed
    Score: 0.026
  4. Human embryonic genetic mosaicism and its effects on development and disease. Nat Rev Genet. 2024 Oct; 25(10):698-714.
    View in: PubMed
    Score: 0.025
  5. SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation. Cell Stem Cell. 2023 11 02; 30(11):1503-1519.e8.
    View in: PubMed
    Score: 0.025
  6. DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells. Nat Cell Biol. 2023 04; 25(4):528-539.
    View in: PubMed
    Score: 0.024
  7. PPM1D in Solid and Hematologic Malignancies: Friend and Foe? Mol Cancer Res. 2022 09 02; 20(9):1365-1378.
    View in: PubMed
    Score: 0.023
  8. Clonal hematopoiesis: mechanisms driving dominance of stem cell clones. Blood. 2020 10 01; 136(14):1590-1598.
    View in: PubMed
    Score: 0.020
  9. Where There's Smoke, There's Fire: Inflammation Drives MDS. Trends Immunol. 2020 07; 41(7):558-560.
    View in: PubMed
    Score: 0.019
  10. Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity. Mol Cell. 2020 05 07; 78(3):506-521.e6.
    View in: PubMed
    Score: 0.019
  11. Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis. Blood. 2020 03 12; 135(11):845-856.
    View in: PubMed
    Score: 0.019
  12. Environmental influences on clonal hematopoiesis. Exp Hematol. 2020 03; 83:66-73.
    View in: PubMed
    Score: 0.019
  13. Single-cell technology meets hematology: introduction to a review series. Blood. 2019 03 28; 133(13):1387-1388.
    View in: PubMed
    Score: 0.018
  14. New insights into the biology of acute myeloid leukemia with mutated NPM1. Int J Hematol. 2019 Aug; 110(2):150-160.
    View in: PubMed
    Score: 0.018
  15. DNA methylation and de-methylation using hybrid site-targeting proteins. Genome Biol. 2018 11 06; 19(1):187.
    View in: PubMed
    Score: 0.017
  16. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy. Cell Stem Cell. 2018 11 01; 23(5):700-713.e6.
    View in: PubMed
    Score: 0.017
  17. Mutant NPM1 Maintains the Leukemic State through HOX Expression. Cancer Cell. 2018 09 10; 34(3):499-512.e9.
    View in: PubMed
    Score: 0.017
  18. Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9. J Vis Exp. 2018 04 10; (134).
    View in: PubMed
    Score: 0.017
  19. DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A. Genome Biol. 2017 09 18; 18(1):176.
    View in: PubMed
    Score: 0.016
  20. Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein. Nat Commun. 2017 07 11; 8:16026.
    View in: PubMed
    Score: 0.016
  21. DNMT3A in Leukemia. Cold Spring Harb Perspect Med. 2017 Feb 01; 7(2).
    View in: PubMed
    Score: 0.015
  22. Genome-Wide Analysis of DNA Methylation in Hematopoietic Cells: DNA Methylation Analysis by WGBS. Methods Mol Biol. 2017; 1633:137-149.
    View in: PubMed
    Score: 0.015
  23. DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood. 2016 08 18; 128(7):971-81.
    View in: PubMed
    Score: 0.015
  24. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell. 2016 06 13; 29(6):922-934.
    View in: PubMed
    Score: 0.015
  25. Noncoding Regulatory RNAs in Hematopoiesis. Curr Top Dev Biol. 2016; 118:245-70.
    View in: PubMed
    Score: 0.014
  26. Stem cells and healthy aging. Science. 2015 Dec 04; 350(6265):1199-204.
    View in: PubMed
    Score: 0.014
  27. Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments. Nat Rev Mol Cell Biol. 2015 May; 16(5):299-309.
    View in: PubMed
    Score: 0.014
  28. Introduction to a review series on hematopoietic stem cells. Blood. 2015 Apr 23; 125(17):2587.
    View in: PubMed
    Score: 0.014
  29. DNMT3A in haematological malignancies. Nat Rev Cancer. 2015 Mar; 15(3):152-65.
    View in: PubMed
    Score: 0.013
  30. Dynamic DNA methylation discovered during HSC differentiation. Cell Cycle. 2015; 14(5):693-4.
    View in: PubMed
    Score: 0.013
  31. Perspectives and future directions for epigenetics in hematology. Blood. 2013 Jun 27; 121(26):5131-7.
    View in: PubMed
    Score: 0.012
  32. Flow cytometry analysis of murine hematopoietic stem cells. Cytometry A. 2013 Jan; 83(1):27-37.
    View in: PubMed
    Score: 0.011
  33. Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet. 2011 Dec 04; 44(1):23-31.
    View in: PubMed
    Score: 0.011
  34. Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells. PLoS One. 2011; 6(10):e26410.
    View in: PubMed
    Score: 0.011
  35. Bridge over troubled stem cells. Mol Ther. 2011 Oct; 19(10):1756-8.
    View in: PubMed
    Score: 0.011
  36. Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nat Rev Immunol. 2011 Sep 09; 11(10):685-92.
    View in: PubMed
    Score: 0.011
  37. Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. Blood. 2011 Aug 11; 118(6):1525-33.
    View in: PubMed
    Score: 0.010
  38. Direct conversion of skin cells into blood: alchemy or science? Mol Ther. 2011 Feb; 19(2):227-8.
    View in: PubMed
    Score: 0.010
  39. Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans. PLoS One. 2011 Jan 21; 6(1):e16317.
    View in: PubMed
    Score: 0.010
  40. Inflammatory signals regulate hematopoietic stem cells. Trends Immunol. 2011 Feb; 32(2):57-65.
    View in: PubMed
    Score: 0.010
  41. LYL1 degradation by the proteasome is directed by a N-terminal PEST rich site in a phosphorylation-independent manner. PLoS One. 2010 Sep 10; 5(9).
    View in: PubMed
    Score: 0.010
  42. Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells. Exp Hematol. 2010 May; 38(5):403-16.
    View in: PubMed
    Score: 0.010
  43. Mechanisms of hematopoietic stem cell aging. Exp Gerontol. 2010 Apr; 45(4):286-90.
    View in: PubMed
    Score: 0.009
  44. Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival. Cell Stem Cell. 2009 Feb 06; 4(2):180-6.
    View in: PubMed
    Score: 0.009
  45. Mouse hematopoietic stem cell identification and analysis. Cytometry A. 2009 Jan; 75(1):14-24.
    View in: PubMed
    Score: 0.009
  46. Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol. 2007 Aug; 5(8):e201.
    View in: PubMed
    Score: 0.008
  47. Pluripotentiality and conditional transgene regulation in human embryonic stem cells expressing insulated tetracycline-ON transactivator. Stem Cells. 2007 Oct; 25(10):2559-66.
    View in: PubMed
    Score: 0.008
  48. Hematopoietic stem cell aging: wrinkles in stem cell potential. Stem Cell Rev. 2007; 3(3):201-11.
    View in: PubMed
    Score: 0.008
  49. Purification of hematopoietic stem cells using the side population. Methods Enzymol. 2006; 420:255-64.
    View in: PubMed
    Score: 0.007
  50. Roles of Sca-1 in hematopoietic stem/progenitor cell function. Exp Hematol. 2005 Jul; 33(7):836-43.
    View in: PubMed
    Score: 0.007
  51. Advancing the fast-paced field of stem cell research: stem cells increases from 6 to 10 issues in its 23rd year of publication. Stem Cells. 2005; 23(1):1-2.
    View in: PubMed
    Score: 0.007
  52. Plasticity and tissue regenerative potential of bone marrow-derived cells. Stem Cell Rev. 2005; 1(1):65-9.
    View in: PubMed
    Score: 0.007
  53. Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol. 2004 Oct; 2(10):e301.
    View in: PubMed
    Score: 0.007
  54. Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system. J Neurosci Res. 2004 Apr 15; 76(2):157-68.
    View in: PubMed
    Score: 0.006
  55. Stem cell plasticity: from transdifferentiation to macrophage fusion. Cell Prolif. 2004 Feb; 37(1):55-65.
    View in: PubMed
    Score: 0.006
  56. Incipient clonal hematopoiesis is accelerated following CD30.CAR-T therapy. Cytotherapy. 2024 03; 26(3):261-265.
    View in: PubMed
    Score: 0.006
  57. Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors. JCO Precis Oncol. 2023 08; 7:e2300070.
    View in: PubMed
    Score: 0.006
  58. Techniques for the study of adult stem cells: be fruitful and multiply. Biotechniques. 2003 Mar; 34(3):572-8, 580-4, 586-91.
    View in: PubMed
    Score: 0.006
  59. Adenoviral transduction of mouse hematopoietic stem cells. Mol Ther. 2003 Mar; 7(3):334-40.
    View in: PubMed
    Score: 0.006
  60. The therapeutic potential of stem cells from adults. BMJ. 2002 Aug 17; 325(7360):372-6.
    View in: PubMed
    Score: 0.006
  61. First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein-Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation. J Med Chem. 2022 08 11; 65(15):10554-10566.
    View in: PubMed
    Score: 0.006
  62. Hematopoietic, vascular and cardiac fates of bone marrow-derived stem cells. Gene Ther. 2002 May; 9(10):648-52.
    View in: PubMed
    Score: 0.006
  63. Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome. Haematologica. 2022 04 01; 107(4):887-898.
    View in: PubMed
    Score: 0.006
  64. Stem cells: a minireview. J Cell Biochem Suppl. 2002; 38:1-6.
    View in: PubMed
    Score: 0.005
  65. Stem cells: is there a future in plastics? Curr Opin Cell Biol. 2001 Dec; 13(6):662-5.
    View in: PubMed
    Score: 0.005
  66. Somatic stem cell plasticity: current evidence and emerging concepts. Exp Hematol. 2001 Dec; 29(12):1361-70.
    View in: PubMed
    Score: 0.005
  67. Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities. Blood Adv. 2021 10 12; 5(19):3876-3890.
    View in: PubMed
    Score: 0.005
  68. Common origins of blood and blood vessels in adults? Differentiation. 2001 Oct; 68(4-5):186-92.
    View in: PubMed
    Score: 0.005
  69. Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor. Cancer Discov. 2022 01; 12(1):220-235.
    View in: PubMed
    Score: 0.005
  70. A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia. Blood. 2001 Aug 15; 98(4):1166-73.
    View in: PubMed
    Score: 0.005
  71. Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL. Cancer Res. 2021 10 01; 81(19):5033-5046.
    View in: PubMed
    Score: 0.005
  72. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest. 2001 Jun; 107(11):1395-402.
    View in: PubMed
    Score: 0.005
  73. Stem cell plasticity in muscle and bone marrow. Ann N Y Acad Sci. 2001 Jun; 938:208-18; discussion 218-20.
    View in: PubMed
    Score: 0.005
  74. A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells. Nat Commun. 2020 02 06; 11(1):740.
    View in: PubMed
    Score: 0.005
  75. WIP1 dephosphorylation of p27Kip1 Serine 140 destabilizes p27Kip1 and reverses anti-proliferative effects of ATM phosphorylation. Cell Cycle. 2020 02; 19(4):479-491.
    View in: PubMed
    Score: 0.005
  76. Introduction: Focus on hematology. CD34(+) or CD34(-): does it really matter? Blood. 1999 Oct 15; 94(8):2545-7.
    View in: PubMed
    Score: 0.005
  77. Mutations in the DNMT3A DNA methyltransferase in acute myeloid leukemia patients cause both loss and gain of function and differential regulation by protein partners. J Biol Chem. 2019 03 29; 294(13):4898-4910.
    View in: PubMed
    Score: 0.004
  78. Homeobox oncogene activation by pan-cancer DNA hypermethylation. Genome Biol. 2018 08 10; 19(1):108.
    View in: PubMed
    Score: 0.004
  79. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med. 1997 Dec; 3(12):1337-45.
    View in: PubMed
    Score: 0.004
  80. Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9. Cell Rep. 2016 10 25; 17(5):1453-1461.
    View in: PubMed
    Score: 0.004
  81. Oncometabolite d-2-hydroxyglutarate impairs a-ketoglutarate dehydrogenase and contractile function in rodent heart. Proc Natl Acad Sci U S A. 2016 09 13; 113(37):10436-41.
    View in: PubMed
    Score: 0.004
  82. Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes. Exp Hematol. 2016 08; 44(8):740-4.
    View in: PubMed
    Score: 0.004
  83. Comparative long-term effects of interferon a and hydroxyurea on human hematopoietic progenitor cells. Exp Hematol. 2015 Oct; 43(10):912-918.e2.
    View in: PubMed
    Score: 0.003
  84. Stem Cells and Aging: What's Next? Cell Stem Cell. 2015 Jun 04; 16(6):578-81.
    View in: PubMed
    Score: 0.003
  85. MOABS: model based analysis of bisulfite sequencing data. Genome Biol. 2014 Feb 24; 15(2):R38.
    View in: PubMed
    Score: 0.003
  86. Hematopoietic stem cell development: an epigenetic journey. Curr Top Dev Biol. 2014; 107:39-75.
    View in: PubMed
    Score: 0.003
  87. Large conserved domains of low DNA methylation maintained by Dnmt3a. Nat Genet. 2014 Jan; 46(1):17-23.
    View in: PubMed
    Score: 0.003
  88. Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome. PLoS Genet. 2012; 8(5):e1002692.
    View in: PubMed
    Score: 0.003
  89. The Hematopoietic Expression Viewer: expanding mobile apps as a scientific tool. Bioinformatics. 2012 Jul 15; 28(14):1941-2.
    View in: PubMed
    Score: 0.003
  90. Selective elimination of a chemoresistant side population of B-CLL cells by cytotoxic T lymphocytes in subjects receiving an autologous hCD40L/IL-2 tumor vaccine. Leukemia. 2010 Mar; 24(3):563-72.
    View in: PubMed
    Score: 0.002
  91. Chk1 haploinsufficiency results in anemia and defective erythropoiesis. PLoS One. 2010 Jan 05; 5(1):e8581.
    View in: PubMed
    Score: 0.002
  92. Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression. Mol Cancer. 2009 Nov 18; 8:106.
    View in: PubMed
    Score: 0.002
  93. Bringing cardiovascular cell-based therapy to clinical application: perspectives based on a National Heart, Lung, and Blood Institute Cell Therapy Working Group meeting. Am Heart J. 2007 May; 153(5):732-42.
    View in: PubMed
    Score: 0.002
  94. Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways. Blood. 2007 Mar 01; 109(5):1897-907.
    View in: PubMed
    Score: 0.002
  95. A distinct "side population" of cells in human tumor cells: implications for tumor biology and therapy. Cell Cycle. 2005 Feb; 4(2):203-5.
    View in: PubMed
    Score: 0.002
  96. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):14228-33.
    View in: PubMed
    Score: 0.002
  97. An in vivo propagated human acute myeloid leukemia expressing ABCA3. Leuk Res. 2004 Mar; 28(3):295-9.
    View in: PubMed
    Score: 0.002
  98. Isolation and characterization of functional mammary gland stem cells. Cell Prolif. 2003 Oct; 36 Suppl 1:17-32.
    View in: PubMed
    Score: 0.002
  99. Complement-fixing CD45 monoclonal antibodies to facilitate stem cell transplantation in mouse and man. Ann N Y Acad Sci. 2003 May; 996:80-8.
    View in: PubMed
    Score: 0.001
  100. Realistic prospects for stem cell therapeutics. Hematology Am Soc Hematol Educ Program. 2003; 398-418.
    View in: PubMed
    Score: 0.001
  101. Hoechst dye efflux reveals a novel CD7(+)CD34(-) lymphoid progenitor in human umbilical cord blood. Blood. 2000 Sep 15; 96(6):2125-33.
    View in: PubMed
    Score: 0.001
  102. Effects of an Rb mutation in the mouse. Nature. 1992 Sep 24; 359(6393):295-300.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.