JEFFREY NOEBELS to Disease Models, Animal
This is a "connection" page, showing publications JEFFREY NOEBELS has written about Disease Models, Animal.
Connection Strength
1.805
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A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment. J Neurosci. 2009 Jul 08; 29(27):8752-63.
Score: 0.157
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Genetic mouse models of essential tremor: are they essential? J Clin Invest. 2005 Mar; 115(3):584-6.
Score: 0.116
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Glioblastoma disrupts cortical network activity at multiple spatial and temporal scales. Nat Commun. 2024 May 27; 15(1):4503.
Score: 0.110
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Modeling human epilepsies in mice. Epilepsia. 2001; 42 Suppl 5:11-5.
Score: 0.087
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Arx expansion mutation perturbs cortical development by augmenting apoptosis without activating innate immunity in a mouse model of X-linked infantile spasms syndrome. Dis Model Mech. 2020 03 30; 13(3).
Score: 0.082
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Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms. Brain. 2020 01 01; 143(1):161-174.
Score: 0.081
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Single gene defects in mice: the role of voltage-dependent calcium channels in absence models. Epilepsy Res. 1999 Sep; 36(2-3):111-22.
Score: 0.079
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Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy. J Neurosci. 2016 Jan 13; 36(2):405-18.
Score: 0.062
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Shift in interictal relative gamma power as a novel biomarker for drug response in two mouse models of absence epilepsy. Epilepsia. 2016 Jan; 57(1):79-88.
Score: 0.061
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Early rescue of interneuron disease trajectory in developmental epilepsies. Curr Opin Neurobiol. 2016 Feb; 36:82-8.
Score: 0.061
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Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models. Sci Transl Med. 2015 Apr 08; 7(282):282ra46.
Score: 0.058
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Bexarotene reduces network excitability in models of Alzheimer's disease and epilepsy. Neurobiol Aging. 2014 Sep; 35(9):2091-5.
Score: 0.054
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Neonatal estradiol stimulation prevents epilepsy in Arx model of X-linked infantile spasms syndrome. Sci Transl Med. 2014 Jan 22; 6(220):220ra12.
Score: 0.054
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Issues related to development of new antiseizure treatments. Epilepsia. 2013 Aug; 54 Suppl 4:24-34.
Score: 0.052
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Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy. J Neurosci. 2013 Jan 23; 33(4):1651-9.
Score: 0.050
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Interneuron, interrupted: molecular pathogenesis of ARX mutations and X-linked infantile spasms. Curr Opin Neurobiol. 2012 Oct; 22(5):859-65.
Score: 0.048
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Knockout of Zn transporters Zip-1 and Zip-3 attenuates seizure-induced CA1 neurodegeneration. J Neurosci. 2011 Jan 05; 31(1):97-104.
Score: 0.043
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A perfect storm: Converging paths of epilepsy and Alzheimer's dementia intersect in the hippocampal formation. Epilepsia. 2011 Jan; 52 Suppl 1:39-46.
Score: 0.043
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Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3. PLoS One. 2010 Aug 20; 5(8):e12278.
Score: 0.042
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Expanded alternative splice isoform profiling of the mouse Cav3.1/alpha1G T-type calcium channel. BMC Mol Biol. 2009 May 29; 10:53.
Score: 0.039
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Masking epilepsy by combining two epilepsy genes. Nat Neurosci. 2007 Dec; 10(12):1554-8.
Score: 0.035
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Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy. Elife. 2025 Jan 06; 13.
Score: 0.029
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Elevated thalamic low-voltage-activated currents precede the onset of absence epilepsy in the SNAP25-deficient mouse mutant coloboma. J Neurosci. 2004 Jun 02; 24(22):5239-48.
Score: 0.028
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Mutations in high-voltage-activated calcium channel genes stimulate low-voltage-activated currents in mouse thalamic relay neurons. J Neurosci. 2002 Aug 01; 22(15):6362-71.
Score: 0.024
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Calcium channel defects in models of inherited generalized epilepsy. Epilepsia. 2000 Aug; 41(8):1074-5.
Score: 0.021
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PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis. Nature. 2020 02; 578(7793):166-171.
Score: 0.020
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Therapeutic inhibition of mTORC2 rescues the behavioral and neurophysiological abnormalities associated with Pten-deficiency. Nat Med. 2019 11; 25(11):1684-1690.
Score: 0.020
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Single-gene models of epilepsy. Adv Neurol. 1999; 79:227-38.
Score: 0.019
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Asynchronous suppression of visual cortex during absence seizures in stargazer mice. Nat Commun. 2018 05 16; 9(1):1938.
Score: 0.018
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Standards for data acquisition and software-based analysis of in?vivo electroencephalography recordings from animals. A TASK1-WG5 report of the AES/ILAE Translational Task Force of the ILAE. Epilepsia. 2017 11; 58 Suppl 4:53-67.
Score: 0.017
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Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death. Neuron. 2014 Sep 03; 83(5):1159-71.
Score: 0.014
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Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease. J Neurosci. 2014 Mar 12; 34(11):3826-40.
Score: 0.014
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Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron. 2012 Sep 20; 75(6):1067-80.
Score: 0.012
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Identification of new epilepsy treatments: issues in preclinical methodology. Epilepsia. 2012 Mar; 53(3):571-82.
Score: 0.012
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MeCP2 is critical within HoxB1-derived tissues of mice for normal lifespan. J Neurosci. 2011 Jul 13; 31(28):10359-70.
Score: 0.011
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Amyloid-?/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. J Neurosci. 2011 Jan 12; 31(2):700-11.
Score: 0.011
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Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature. 2010 Nov 11; 468(7321):263-9.
Score: 0.011
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Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization. J Physiol. 2008 Jul 15; 586(14):3405-23.
Score: 0.009
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Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3. Neuron. 2008 Jan 24; 57(2):263-75.
Score: 0.009
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Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. 2007 Sep 06; 55(5):697-711.
Score: 0.009
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Rai1 deficiency in mice causes learning impairment and motor dysfunction, whereas Rai1 heterozygous mice display minimal behavioral phenotypes. Hum Mol Genet. 2007 Aug 01; 16(15):1802-13.
Score: 0.008
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BK channel beta4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures. Nat Neurosci. 2005 Dec; 8(12):1752-9.
Score: 0.008
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Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. Hum Mol Genet. 2004 Nov 01; 13(21):2679-89.
Score: 0.007
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Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1). Cell Death Differ. 2003 Dec; 10(12):1329-35.
Score: 0.007
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Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance. Mol Cell Biol. 2003 May; 23(10):3646-55.
Score: 0.006
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Genetic and phenotypic analysis of the mouse mutant mh2J, an Ap3d allele caused by IAP element insertion. Mamm Genome. 2003 Mar; 14(3):157-67.
Score: 0.006
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Models for epilepsy and epileptogenesis: report from the NIH workshop, Bethesda, Maryland. Epilepsia. 2002 Nov; 43(11):1410-20.
Score: 0.006
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Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3. Neuron. 2002 Jul 18; 35(2):243-54.
Score: 0.006
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Analysis of inherited epilepsy using single locus mutations in mice. Fed Proc. 1979 Sep; 38(10):2405-10.
Score: 0.005
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Progressive ataxia, myoclonic epilepsy and cerebellar apoptosis in cystatin B-deficient mice. Nat Genet. 1998 Nov; 20(3):251-8.
Score: 0.005
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Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. Neuron. 1998 Oct; 21(4):799-811.
Score: 0.005
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Upregulation of L-type Ca2+ channels in reactive astrocytes after brain injury, hypomyelination, and ischemia. J Neurosci. 1998 Apr 01; 18(7):2321-34.
Score: 0.004
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Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci U S A. 1997 Dec 09; 94(25):14060-5.
Score: 0.004
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A candidate model for Angelman syndrome in the mouse. Mamm Genome. 1997 Jul; 8(7):472-8.
Score: 0.004