DAVIDROWLEYDAVID ROWLEY0.000000000000000.000000000000002909ROWLEY, DAVIDProfessorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 810699Authorship 830485Authorship 848961Authorship 862093Authorship 889881Authorship 988772Authorship 991249Authorship 990661Authorship 1008907Authorship 1091412Authorship 1138588Authorship 1193921Authorship 12122313Authorship 224936Authorship 228488Authorship 243752Authorship 255332Authorship 160793524819504Gill AC, Nelson EA, Mian AI, Raphael JL, Rowley DR, Mcguire ALMedical teacherResponding to moderate breaches in professionalism: an intervention for medical students. Med Teach. 2015 Feb; 37(2):136-9.Med Teach2014-05-12T00:00:002014Responding to moderate breaches in professionalism: an intervention for medical students.Authorship 272684Authorship 275053Authorship 308752Authorship 344921Cancer BiologyGenitourinary Medical OncologyRadiation OncologyMD AndersonSTEVEN JAYFRANKSTEVEN JAY FRANK8958FRANK, STEVEN JAYProfessorTIMOTHYTHOMPSONTIMOTHY THOMPSON9463THOMPSON, TIMOTHYProfessorCHRISTOPHER JLOGOTHETISCHRISTOPHER J LOGOTHETIS8480LOGOTHETIS, CHRISTOPHER JProfessorRAGHUKALLURIRAGHU KALLURI9841KALLURI, RAGHUProfessorAuthorship 429631Authorship 728842Authorship 743562Authorship 752645Authorship 802022Authorship 946516Authorship 9970422862128Tindall DJ, Rowley DR, Murthy L, Lipshultz LI, Chang CHInternational review of cytologyStructure and biochemistry of the Sertoli cell. Int Rev Cytol. 1985; 94:127-49.Int Rev Cytol1985-01-01T00:00:001985Structure and biochemistry of the Sertoli cell.447491Thompson SA, Rowley DR, Heidger PMInvestigative urologyEffects of estrogen upon the fine structure of epithelium and stroma in the rat ventral prostate gland. Invest Urol. 1979 Jul; 17(1):83-9.Invest Urol1979-07-01T00:00:001979Effects of estrogen upon the fine structure of epithelium and stroma in the rat ventral prostate gland.6661431Chang CH, Rowley DR, Tindall DJBiochemistryPurification and characterization of the androgen receptor from rat ventral prostate. Biochemistry. 1983 Dec 20; 22(26):6170-5.Biochemistry1983-12-20T00:00:001983Purification and characterization of the androgen receptor from rat ventral prostate.6208540Murthy LR, Chang CH, Rowley DR, Scardino PT, Tindall DJThe ProstatePhysicochemical characterization of the androgen receptor from hyperplastic human prostate. Prostate. 1984; 5(6):567-79.Prostate1984-01-01T00:00:001984Physicochemical characterization of the androgen receptor from hyperplastic human prostate.6598324Tindall DJ, Chang CH, Lobl TJ, Rowley DRAnnals of the New York Academy of SciencesMolecular properties of the androgen receptor in rat ventral prostate. Ann N Y Acad Sci. 1984; 438:39-53.Ann N Y Acad Sci1984-01-01T00:00:001984Molecular properties of the androgen receptor in rat ventral prostate.6714164Rowley DR, Chang CH, Tindall DJEndocrinologyEffects of sodium molybdate on the androgen receptor from the R3327 prostatic tumor. Endocrinology. 1984 May; 114(5):1776-83.Endocrinology1984-05-01T00:00:001984Effects of sodium molybdate on the androgen receptor from the R3327 prostatic tumor.7850789Rowley DR, Dang TD, McBride L, Gerdes MJ, Lu B, Larsen MCancer researchBeta-2 microglobulin is mitogenic to PC-3 prostatic carcinoma cells and antagonistic to transforming growth factor beta 1 action. Cancer Res. 1995 Feb 15; 55(4):781-6.Cancer Res1995-02-15T00:00:001995Beta-2 microglobulin is mitogenic to PC-3 prostatic carcinoma cells and antagonistic to transforming growth factor beta 1 action.6982067Chang CH, Rowley DR, Lobl TJ, Tindall DJBiochemistryPurification and characterization of androgen receptor from steer seminal vesicle. Biochemistry. 1982 Aug 17; 21(17):4102-9.Biochemistry1982-08-17T00:00:001982Purification and characterization of androgen receptor from steer seminal vesicle.6607463Rowley DR, Thompson SA, Lubaroff DM, Heidger PMThe ProstateAndrogen receptor binding characteristics in the cytosol of the rat dorsolateral prostate gland and the Dunning R-3327 prostatic adenocarcinoma. Prostate. 1984; 5(1):101-11.Prostate1984-01-01T00:00:001984Androgen receptor binding characteristics in the cytosol of the rat dorsolateral prostate gland and the Dunning R-3327 prostatic adenocarcinoma.9037277Sutton MA, Berkman SA, Chen SH, Block A, Dang TD, Kattan MW, Wheeler TM, Rowley DR, Woo SL, Lerner SPUrologyAdenovirus-mediated suicide gene therapy for experimental bladder cancer. Urology. 1997 Feb; 49(2):173-80.Urology1997-02-01T00:00:001997Adenovirus-mediated suicide gene therapy for experimental bladder cancer.9487120Gerdes MJ, Larsen M, McBride L, Dang TD, Lu B, Rowley DRThe journal of histochemistry and cytochemistry : official journal of the Histochemistry SocietyLocalization of transforming growth factor-beta1 and type II receptor in developing normal human prostate and carcinoma tissues. J Histochem Cytochem. 1998 Mar; 46(3):379-88.J Histochem Cytochem1998-03-01T00:00:001998Localization of transforming growth factor-beta1 and type II receptor in developing normal human prostate and carcinoma tissues.10453285Rowley DRCancer metastasis reviewsWhat might a stromal response mean to prostate cancer progression? Cancer Metastasis Rev. 1998-1999; 17(4):411-9.Cancer Metastasis Rev1998-01-01T00:00:001998What might a stromal response mean to prostate cancer progression?Authorship 29703528603596Gerdes MJ, Dang TD, Lu B, Larsen M, McBride L, Rowley DREndocrinologyAndrogen-regulated proliferation and gene transcription in a prostate smooth muscle cell line (PS-1). Endocrinology. 1996 Mar; 137(3):864-72.Endocrinology1996-03-01T00:00:001996Androgen-regulated proliferation and gene transcription in a prostate smooth muscle cell line (PS-1).26184673Montico F, Kido LA, San Martin R, Rowley DR, Cagnon VHThe ProstateReactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences. Prostate. 2015 Oct; 75(14):1643-61.Prostate2015-07-17T00:00:002015Reactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences.10985951Sutton MA, Freund CT, Berkman SA, Dang TD, Kattan MW, Wheeler TM, Rowley DR, Lerner SPMolecular therapy : the journal of the American Society of Gene TherapyIn vivo adenovirus-mediated suicide gene therapy of orthotopic bladder cancer. Mol Ther. 2000 Sep; 2(3):211-7.Mol Ther2000-09-01T00:00:002000In vivo adenovirus-mediated suicide gene therapy of orthotopic bladder cancer.11696814Tuxhorn JA, Ayala GE, Rowley DRThe Journal of urologyReactive stroma in prostate cancer progression. J Urol. 2001 Dec; 166(6):2472-83.J Urol2001-12-01T00:00:002001Reactive stroma in prostate cancer progression.12036948Tuxhorn JA, McAlhany SJ, Dang TD, Ayala GE, Rowley DRCancer researchStromal cells promote angiogenesis and growth of human prostate tumors in a differential reactive stroma (DRS) xenograft model. Cancer Res. 2002 Jun 01; 62(11):3298-307.Cancer Res2002-06-01T00:00:002002Stromal cells promote angiogenesis and growth of human prostate tumors in a differential reactive stroma (DRS) xenograft model.12670591Cornell RJ, Rowley D, Wheeler T, Ali N, Ayala GUrologyNeuroepithelial interactions in prostate cancer are enhanced in the presence ofprostatic stroma. Urology. 2003 Apr; 61(4):870-5.Urology2003-04-01T00:00:002003Neuroepithelial interactions in prostate cancer are enhanced in the presence ofprostatic stroma.One Baylor PlazaHouston, 77030TX14522910McAlhany SJ, Ressler SJ, Larsen M, Tuxhorn JA, Yang F, Dang TD, Rowley DRCancer researchPromotion of angiogenesis by ps20 in the differential reactive stroma prostate cancer xenograft model. Cancer Res. 2003 Sep 15; 63(18):5859-65.Cancer Res2003-09-15T00:00:002003Promotion of angiogenesis by ps20 in the differential reactive stroma prostate cancer xenograft model.10928044Freund CT, Sutton MA, Dang T, Contant CF, Rowley D, Lerner SPAnticancer researchAdenovirus-mediated combination suicide and cytokine gene therapy for bladder cancer. Anticancer Res. 2000 May-Jun; 20(3A):1359-65.Anticancer Res2000-05-01T00:00:002000Adenovirus-mediated combination suicide and cytokine gene therapy for bladder cancer.10967136Larsen M, Ressler SJ, Gerdes MJ, Lu B, Byron M, Lawrence JB, Rowley DRMammalian genome : official journal of the International Mammalian Genome SocietyThe WFDC1 gene encoding ps20 localizes to 16q24, a region of LOH in multiple cancers. Mamm Genome. 2000 Sep; 11(9):767-73.Mamm Genome2000-09-01T00:00:002000The WFDC1 gene encoding ps20 localizes to 16q24, a region of LOH in multiple cancers.74Professor14Associate Professor2Adjunct Assistant Professor46Distinguished Emeritus Professor3Adjunct Associate Professor47Distinguished Service ProfessorAuthorship 3215231626753621Bianchi-Frias D, Basom R, Delrow JJ, Coleman IM, Dakhova O, Qu X, Fang M, Franco OE, Ericson NG, Bielas JH, Hayward SW, True L, Morrissey C, Brown L, Bhowmick NA, Rowley D, Ittmann M, Nelson PSMolecular cancer research : MCRCells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations. Mol Cancer Res. 2016 Apr; 14(4):374-84.Mol Cancer Res2016-01-11T00:00:002016Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations.Authorship 325346827403603Farach A, Ding Y, Lee M, Creighton C, Delk NA, Ittmann M, Miles B, Rowley D, Farach-Carson MC, Ayala GEThe ProstateNeuronal Trans-Differentiation in Prostate Cancer Cells. Prostate. 2016 10; 76(14):1312-25.Prostate2016-07-12T00:00:002016Neuronal Trans-Differentiation in Prostate Cancer Cells.27655672Brooks M, Mo Q, Krasnow R, Ho PL, Lee YC, Xiao J, Kurtova A, Lerner S, Godoy G, Jian W, Castro P, Chen F, Rowley D, Ittmann M, Chan KSOncotargetPositive association of collagen type I with non-muscle invasive bladder cancer progression. Oncotarget. 2016 Dec 13; 7(50):82609-82619.Oncotarget2016-12-13T00:00:002016Positive association of collagen type I with non-muscle invasive bladder cancer progression.17942534Alvarez R, Reading J, King DF, Hayes M, Easterbrook P, Farzaneh F, Ressler S, Yang F, Rowley D, Vyakarnam AJournal of virologyWFDC1/ps20 is a novel innate immunomodulatory signature protein of human immunodeficiency virus (HIV)-permissive CD4+ CD45RO+ memory T cells that promotes infection by upregulating CD54 integrin expression and is elevated in HIV type 1 infection. J Virol. 2008 Jan; 82(1):471-86.J Virol2007-10-17T00:00:002007WFDC1/ps20 is a novel innate immunomodulatory signature protein of human immunodeficiency virus (HIV)-permissive CD4+ CD45RO+ memory T cells that promotes infection by upregulating CD54 integrin expression and is elevated in HIV type 1 infection.18314176Schauer IG, Ressler SJ, Tuxhorn JA, Dang TD, Rowley DRUrologyElevated epithelial expression of interleukin-8 correlates with myofibroblast reactive stroma in benign prostatic hyperplasia. Urology. 2008 Jul; 72(1):205-13.Urology2008-03-07T00:00:002008Elevated epithelial expression of interleukin-8 correlates with myofibroblast reactive stroma in benign prostatic hyperplasia.15538284Singh H, Dang TD, Ayala GE, Rowley DRThe Journal of urologyTransforming growth factor-beta1 induced myofibroblasts regulate LNCaP cell death. J Urol. 2004 Dec; 172(6 Pt 1):2421-5.J Urol2004-12-01T00:00:002004Transforming growth factor-beta1 induced myofibroblasts regulate LNCaP cell death.14743470Gerdes MJ, Larsen M, Dang TD, Ressler SJ, Tuxhorn JA, Rowley DRThe ProstateRegulation of rat prostate stromal cell myodifferentiation by androgen and TGF-beta1. Prostate. 2004 Feb 15; 58(3):299-307.Prostate2004-02-15T00:00:002004Regulation of rat prostate stromal cell myodifferentiation by androgen and TGF-beta1.20584703Dixon D, Pollard B, Rowley D, Johnson MQuality & safety in health careApplication of the ICF to referral delay in total joint arthroplasty. Qual Saf Health Care. 2010 Dec; 19(6):e23.Qual Saf Health Care2010-06-27T00:00:002010Application of the ICF to referral delay in total joint arthroplasty.15305341McAlhany SJ, Ayala GE, Frolov A, Ressler SJ, Wheeler TM, Watson JE, Collins C, Rowley DRThe ProstateDecreased stromal expression and increased epithelial expression of WFDC1/ps20 in prostate cancer is associated with reduced recurrence-free survival. Prostate. 2004 Oct 01; 61(2):182-91.Prostate2004-10-01T00:00:002004Decreased stromal expression and increased epithelial expression of WFDC1/ps20 in prostate cancer is associated with reduced recurrence-free survival.2422638Murthy LR, Johnson MP, Rowley DR, Young CY, Scardino PT, Tindall DJThe ProstateCharacterization of steroid receptors in human prostate using mibolerone. Prostate. 1986; 8(3):241-53.Prostate1986-01-01T00:00:001986Characterization of steroid receptors in human prostate using mibolerone.2432928Rowley DR, Premont RT, Johnson MP, Young CY, Tindall DJBiochemistryProperties of an intermediate-sized androgen receptor: association with RNA. Biochemistry. 1986 Nov 04; 25(22):6988-95.Biochemistry1986-11-04T00:00:001986Properties of an intermediate-sized androgen receptor: association with RNA.16015593Dai H, Li R, Wheeler T, Diaz de Vivar A, Frolov A, Tahir S, Agoulnik I, Thompson T, Rowley D, Ayala GThe ProstatePim-2 upregulation: biological implications associated with disease progression and perinueral invasion in prostate cancer. Prostate. 2005 Nov 01; 65(3):276-86.Prostate2005-11-01T00:00:002005Pim-2 upregulation: biological implications associated with disease progression and perinueral invasion in prostate cancer.16245277Ayala GE, Dai H, Li R, Ittmann M, Thompson TC, Rowley D, Wheeler TMThe ProstateBystin in perineural invasion of prostate cancer. Prostate. 2006 Feb 15; 66(3):266-72.Prostate2006-02-15T00:00:002006Bystin in perineural invasion of prostate cancer.22930558Barron DA, Rowley DREndocrine-related cancerThe reactive stroma microenvironment and prostate cancer progression. Endocr Relat Cancer. 2012 Dec; 19(6):R187-204.Endocr Relat Cancer2012-10-30T00:00:002012The reactive stroma microenvironment and prostate cancer progression.22960155Rogers E, Wang BX, Cui Z, Rowley DR, Ressler SJ, Vyakarnam A, Fish ENAntiviral researchWFDC1/ps20: a host factor that influences the neutrophil response to murine hepatitis virus (MHV) 1 infection. Antiviral Res. 2012 Nov; 96(2):158-68.Antiviral Res2012-09-06T00:00:002012WFDC1/ps20: a host factor that influences the neutrophil response to murine hepatitis virus (MHV) 1 infection.16651608Cher ML, Towler DA, Rafii S, Rowley D, Donahue HJ, Keller E, Herlyn M, Cho EA, Chung LWThe American journal of pathologyCancer interaction with the bone microenvironment: a workshop of the National Institutes of Health Tumor Microenvironment Study Section. Am J Pathol. 2006 May; 168(5):1405-12.Am J Pathol2006-05-01T00:00:002006Cancer interaction with the bone microenvironment: a workshop of the National Institutes of Health Tumor Microenvironment Study Section.16707439Ayala GE, Dai H, Tahir SA, Li R, Timme T, Ittmann M, Frolov A, Wheeler TM, Rowley D, Thompson TCCancer researchStromal antiapoptotic paracrine loop in perineural invasion of prostatic carcinoma. Cancer Res. 2006 May 15; 66(10):5159-64.Cancer Res2006-05-15T00:00:002006Stromal antiapoptotic paracrine loop in perineural invasion of prostatic carcinoma.18206496Yanagisawa N, Li R, Rowley D, Liu H, Kadmon D, Miles BJ, Wheeler TM, Ayala GEHuman pathologyReprint of: Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy. Hum Pathol. 2008 Feb; 39(2):282-91.Hum Pathol2008-02-01T00:00:002008Reprint of: Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy.17637743Yang F, Strand DW, Rowley DROncogeneFibroblast growth factor-2 mediates transforming growth factor-beta action in prostate cancer reactive stroma. Oncogene. 2008 Jan 17; 27(4):450-9.Oncogene2007-07-16T00:00:002007Fibroblast growth factor-2 mediates transforming growth factor-beta action in prostate cancer reactive stroma.17868773Yanagisawa N, Li R, Rowley D, Liu H, Kadmon D, Miles BJ, Wheeler TM, Ayala GEHuman pathologyStromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy. Hum Pathol. 2007 Nov; 38(11):1611-20.Hum Pathol2007-09-14T00:00:002007Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy.Authorship 6053711319047084Ayala GE, Dai H, Powell M, Li R, Ding Y, Wheeler TM, Shine D, Kadmon D, Thompson T, Miles BJ, Ittmann MM, Rowley DClinical cancer research : an official journal of the American Association for Cancer ResearchCancer-related axonogenesis and neurogenesis in prostate cancer. Clin Cancer Res. 2008 Dec 01; 14(23):7593-603.Clin Cancer Res2008-12-01T00:00:002008Cancer-related axonogenesis and neurogenesis in prostate cancer.19592030Farrow B, Berger DH, Rowley DThe Journal of surgical researchTumor-derived pancreatic stellate cells promote pancreatic cancer cell invasion through release of thrombospondin-2. J Surg Res. 2009 Sep; 156(1):155-60.J Surg Res2009-05-03T00:00:002009Tumor-derived pancreatic stellate cells promote pancreatic cancer cell invasion through release of thrombospondin-2.19509179Dakhova O, Ozen M, Creighton CJ, Li R, Ayala G, Rowley D, Ittmann MClinical cancer research : an official journal of the American Association for Cancer ResearchGlobal gene expression analysis of reactive stroma in prostate cancer. Clin Cancer Res. 2009 Jun 15; 15(12):3979-89.Clin Cancer Res2009-06-09T00:00:002009Global gene expression analysis of reactive stroma in prostate cancer.19726060Farrow B, Rowley D, Dang T, Berger DHThe Journal of surgical researchCharacterization of tumor-derived pancreatic stellate cells. J Surg Res. 2009 Nov; 157(1):96-102.J Surg Res2009-05-07T00:00:002009Characterization of tumor-derived pancreatic stellate cells.Authorship 652469527345403Su Q, Zhang B, Zhang L, Dang T, Rowley D, Ittmann M, Xin LOncogeneJagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer. Oncogene. 2017 02 02; 36(5):618-627.Oncogene2016-06-27T00:00:002016Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer.21936833Ressler SJ, Rowley DRBiochemical Society transactionsThe WFDC1 gene: role in wound response and tissue homoeostasis. Biochem Soc Trans. 2011 Oct; 39(5):1455-9.Biochem Soc Trans2011-10-01T00:00:002011The WFDC1 gene: role in wound response and tissue homoeostasis.Authorship 101169921060787Barron DA, Strand DW, Ressler SJ, Dang TD, Hayward SW, Yang F, Ayala GE, Ittmann M, Rowley DRPloS oneTGF-?1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouse. PLoS One. 2010 Oct 29; 5(10):e13751.PLoS One2010-10-29T00:00:002010TGF-?1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouse.21664759Schauer IG, Rowley DRDifferentiation; research in biological diversityThe functional role of reactive stroma in benign prostatic hyperplasia. Differentiation. 2011 Nov-Dec; 82(4-5):200-10.Differentiation2011-06-12T00:00:002011The functional role of reactive stroma in benign prostatic hyperplasia.2454813Young CY, Murthy LR, Prescott JL, Johnson MP, Rowley DR, Cunningham GR, Killian CS, Scardino PT, VonEschenbach A, Tindall DJEndocrinologyMonoclonal antibodies against the androgen receptor: recognition of human and other mammalian androgen receptors. Endocrinology. 1988 Jul; 123(1):601-10.Endocrinology1988-07-01T00:00:001988Monoclonal antibodies against the androgen receptor: recognition of human and other mammalian androgen receptors.Authorship 840819328315427De Vivar AD, Sayeeduddin M, Rowley D, Cubilla A, Miles B, Kadmon D, Ayala GHuman pathologyHistologic features of stromogenic carcinoma of the prostate (carcinomas with reactive stroma grade 3). Hum Pathol. 2017 05; 63:202-211.Hum Pathol2017-03-15T00:00:002017Histologic features of stromogenic carcinoma of the prostate (carcinomas with reactive stroma grade 3).3567912Rowley DR, Tindall DJCancer researchResponses of NBT-II bladder carcinoma cells to conditioned medium from normal fetal urogenital sinus. Cancer Res. 1987 Jun 01; 47(11):2955-60.Cancer Res1987-06-01T00:00:001987Responses of NBT-II bladder carcinoma cells to conditioned medium from normal fetal urogenital sinus.Authorship 8693701128433771Wang W, Meng Y, Dong B, Dong J, Ittmann MM, Creighton CJ, Lu Y, Zhang H, Shen T, Wang J, Rowley DR, Li Y, Chen F, Moore DD, Yang FNeoplasia (New York, N.Y.)A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis. Neoplasia. 2017 May; 19(5):421-428.Neoplasia2017-04-20T00:00:002017A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis.6101199Guerriero V, Rowley DR, Means ARCellProduction and characterization of an antibody to myosin light chain kinase and intracellular localization of the enzyme. Cell. 1981 Dec; 27(3 Pt 2):449-58.Cell1981-12-01T00:00:001981Production and characterization of an antibody to myosin light chain kinase and intracellular localization of the enzyme.6387280Carroll SL, Rowley DR, Chang CH, Tindall DJJournal of steroid biochemistryExchange assay for androgen receptors in the presence of molybdate. J Steroid Biochem. 1984 Oct; 21(4):353-9.J Steroid Biochem1984-10-01T00:00:001984Exchange assay for androgen receptors in the presence of molybdate.6477884Chang CH, Lobl TJ, Rowley DR, Tindall DJBiochemistryAffinity labeling of the androgen receptor in rat prostate cytosol with 17 beta-[(bromoacetyl)oxy]-5 alpha-androstan-3-one. Biochemistry. 1984 May 22; 23(11):2527-33.Biochemistry1984-05-22T00:00:001984Affinity labeling of the androgen receptor in rat prostate cytosol with 17 beta-[(bromoacetyl)oxy]-5 alpha-androstan-3-one.7665628Rowley DR, Dang TD, Larsen M, Gerdes MJ, McBride L, Lu BThe Journal of biological chemistryPurification of a novel protein (ps20) from urogenital sinus mesenchymal cells with growth inhibitory properties in vitro. J Biol Chem. 1995 Sep 15; 270(37):22058-65.J Biol Chem1995-09-15T00:00:001995Purification of a novel protein (ps20) from urogenital sinus mesenchymal cells with growth inhibitory properties in vitro.7748406Southern J, Rowley D, Kretzer FAcademic medicine : journal of the Association of American Medical CollegesUsing the MEDLINE database in a histology laboratory. Acad Med. 1995 May; 70(5):439-40.Acad Med1995-05-01T00:00:001995Using the MEDLINE database in a histology laboratory.9468514Larsen M, Ressler SJ, Lu B, Gerdes MJ, McBride L, Dang TD, Rowley DRThe Journal of biological chemistryMolecular cloning and expression of ps20 growth inhibitor. A novel WAP-type "four-disulfide core" domain protein expressed in smooth muscle. J Biol Chem. 1998 Feb 20; 273(8):4574-84.J Biol Chem1998-02-20T00:00:001998Molecular cloning and expression of ps20 growth inhibitor. A novel WAP-type "four-disulfide core" domain protein expressed in smooth muscle.9681509Gerdes MJ, Dang TD, Larsen M, Rowley DREndocrinologyTransforming growth factor-beta1 induces nuclear to cytoplasmic distribution of androgen receptor and inhibits androgen response in prostate smooth muscle cells. Endocrinology. 1998 Aug; 139(8):3569-77.Endocrinology1998-08-01T00:00:001998Transforming growth factor-beta1 induces nuclear to cytoplasmic distribution of androgen receptor and inhibits androgen response in prostate smooth muscle cells.Authorship 872510928591703Roberts JM, Martin RS, Piyarathna DB, MacKrell JG, Rocha GV, Dodge JA, Coarfa C, Krishnan V, Rowley DR, Weigel NLOncotargetVitamin D receptor activation reduces VCaP xenograft tumor growth and counteracts ERG activity despite induction of TMPRSS2:ERG. Oncotarget. 2017 Jul 04; 8(27):44447-44464.Oncotarget2017-07-04T00:00:002017Vitamin D receptor activation reduces VCaP xenograft tumor growth and counteracts ERG activity despite induction of TMPRSS2:ERG.11062688Freund CT, Tong XW, Block A, Contant CF, Kieback DG, Rowley DR, Lerner SPAnticancer researchAdenovirus-mediated suicide gene therapy for bladder cancer: comparison of the cytomegalovirus- and Rous sarcoma virus-promoter. Anticancer Res. 2000 Sep-Oct; 20(5A):2811-6.Anticancer Res2000-09-01T00:00:002000Adenovirus-mediated suicide gene therapy for bladder cancer: comparison of the cytomegalovirus- and Rous sarcoma virus-promoter.11746267Ayala GE, Wheeler TM, Shine HD, Schmelz M, Frolov A, Chakraborty S, Rowley DThe ProstateIn vitro dorsal root ganglia and human prostate cell line interaction: redefining perineural invasion in prostate cancer. Prostate. 2001 Nov 01; 49(3):213-23.Prostate2001-11-01T00:00:002001In vitro dorsal root ganglia and human prostate cell line interaction: redefining perineural invasion in prostate cancer.12231536Tuxhorn JA, Ayala GE, Smith MJ, Smith VC, Dang TD, Rowley DRClinical cancer research : an official journal of the American Association for Cancer ResearchReactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling. Clin Cancer Res. 2002 Sep; 8(9):2912-23.Clin Cancer Res2002-09-01T00:00:002002Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling.1612028Rowley DREndocrinologyGlucocorticoid regulation of transforming growth factor-beta activation in urogenital sinus mesenchymal cells. Endocrinology. 1992 Jul; 131(1):471-8.Endocrinology1992-07-01T00:00:001992Glucocorticoid regulation of transforming growth factor-beta activation in urogenital sinus mesenchymal cells.12746833Li M, Ittmann MM, Rowley DR, Knowlton AA, Vaid AK, Epner DEThe ProstateGlutathione S-transferase pi is upregulated in the stromal compartment of hormone independent prostate cancer. Prostate. 2003 Jul 01; 56(2):98-105.Prostate2003-07-01T00:00:002003Glutathione S-transferase pi is upregulated in the stromal compartment of hormone independent prostate cancer.12810206Freund CT, Tong XW, Rowley D, Engehausen D, Frolov A, Kieback DG, Lerner SPUrologic oncologyCombination of adenovirus-mediated thymidine kinase gene therapy with cytotoxic chemotherapy in bladder cancer in vitro. Urol Oncol. 2003 May-Jun; 21(3):197-205.Urol Oncol2003-05-01T00:00:002003Combination of adenovirus-mediated thymidine kinase gene therapy with cytotoxic chemotherapy in bladder cancer in vitro.14581350Ayala G, Tuxhorn JA, Wheeler TM, Frolov A, Scardino PT, Ohori M, Wheeler M, Spitler J, Rowley DRClinical cancer research : an official journal of the American Association for Cancer ResearchReactive stroma as a predictor of biochemical-free recurrence in prostate cancer. Clin Cancer Res. 2003 Oct 15; 9(13):4792-801.Clin Cancer Res2003-10-15T00:00:002003Reactive stroma as a predictor of biochemical-free recurrence in prostate cancer.1730568Rowley DRIn vitro cellular & developmental biology : journal of the Tissue Culture AssociationCharacterization of a fetal urogenital sinus mesenchymal cell line U4F: secretion of a negative growth regulatory activity. In Vitro Cell Dev Biol. 1992 Jan; 28A(1):29-38.In Vitro Cell Dev Biol1992-01-01T00:00:001992Characterization of a fetal urogenital sinus mesenchymal cell line U4F: secretion of a negative growth regulatory activity.15305342Watson JE, Kamkar S, James K, Kowbel D, Andaya A, Paris PL, Simko J, Carroll P, McAlhany S, Rowley D, Collins CThe ProstateMolecular analysis of WFDC1/ps20 gene in prostate cancer. Prostate. 2004 Oct 01; 61(2):192-9.Prostate2004-10-01T00:00:002004Molecular analysis of WFDC1/ps20 gene in prostate cancer.15342391Ayala GE, Dai H, Ittmann M, Li R, Powell M, Frolov A, Wheeler TM, Thompson TC, Rowley DCancer researchGrowth and survival mechanisms associated with perineural invasion in prostate cancer. Cancer Res. 2004 Sep 01; 64(17):6082-90.Cancer Res2004-09-01T00:00:002004Growth and survival mechanisms associated with perineural invasion in prostate cancer.16204060Yang F, Tuxhorn JA, Ressler SJ, McAlhany SJ, Dang TD, Rowley DRCancer researchStromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis. Cancer Res. 2005 Oct 01; 65(19):8887-95.Cancer Res2005-10-01T00:00:002005Stromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis.17097719Dai H, Li R, Wheeler T, Ozen M, Ittmann M, Anderson M, Wang Y, Rowley D, Younes M, Ayala GEHuman pathologyEnhanced survival in perineural invasion of pancreatic cancer: an in vitro approach. Hum Pathol. 2007 Feb; 38(2):299-307.Hum Pathol2006-11-13T00:00:002006Enhanced survival in perineural invasion of pancreatic cancer: an in vitro approach.17928375Keller ET, Rowley DR, Tomlins SA, Drake CG, Kantoff PW, Pienta KJ, Montie JE, Carter HB, Hruszkewicz AM, Gomez J, Mohla S, Getzenberg RHCancer researchEleventh Prouts Neck Meeting on Prostate Cancer: emerging strategies in prostate cancer therapy. Cancer Res. 2007 Oct 15; 67(20):9613-5.Cancer Res2007-10-10T00:00:002007Eleventh Prouts Neck Meeting on Prostate Cancer: emerging strategies in prostate cancer therapy.28968863Spencer JL, Lahon A, Tran LL, Arya RP, Kneubehl AR, Vogt MB, Xavier D, Rowley DR, Kimata JT, Rico-Hesse RRThe Journal of infectious diseasesReplication of Zika Virus in Human Prostate Cells: A Potential Source of Sexually Transmitted Virus. J Infect Dis. 2018 01 30; 217(4):538-547.J Infect Dis2018-01-30T00:00:002018Replication of Zika Virus in Human Prostate Cells: A Potential Source of Sexually Transmitted Virus.18593913Shao LJ, Shi HY, Ayala G, Rowley D, Zhang MCancer researchHaploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostate. Cancer Res. 2008 Jul 01; 68(13):5143-51.Cancer Res2008-07-01T00:00:002008Haploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostate.19021203Schauer IG, Ressler SJ, Rowley DRThe ProstateKeratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model. Prostate. 2009 Mar 01; 69(4):373-84.Prostate2009-03-01T00:00:002009Keratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model.21224046Ayala GE, Muezzinoglu B, Hammerich KH, Frolov A, Liu H, Scardino PT, Li R, Sayeeduddin M, Ittmann MM, Kadmon D, Miles BJ, Wheeler TM, Rowley DRThe American journal of pathologyDetermining prostate cancer-specific death through quantification of stromogenic carcinoma area in prostatectomy specimens. Am J Pathol. 2011 Jan; 178(1):79-87.Am J Pathol2010-12-23T00:00:002010Determining prostate cancer-specific death through quantification of stromogenic carcinoma area in prostatectomy specimens.2440474Johnson MP, Young CY, Rowley DR, Tindall DJBiochemistryA common molecular weight of the androgen receptor monomer in different target tissues. Biochemistry. 1987 Jun 02; 26(11):3174-82.Biochemistry1987-06-02T00:00:001987A common molecular weight of the androgen receptor monomer in different target tissues.Authorship 88462115Authorship 8847248Authorship 885438828916657San Martin R, Pathak R, Jain A, Jung SY, Hilsenbeck SG, Pi?a-Barba MC, Sikora AG, Pienta KJ, Rowley DRCancer researchTenascin-C and Integrin a9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment. Cancer Res. 2017 11 01; 77(21):5977-5988.Cancer Res2017-09-15T00:00:002017Tenascin-C and Integrin a9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment.29131367Coarfa C, Florentin D, Putluri N, Ding Y, Au J, He D, Ragheb A, Frolov A, Michailidis G, Lee M, Kadmon D, Miles B, Smith C, Ittmann M, Rowley D, Sreekumar A, Creighton CJ, Ayala GThe ProstateInfluence of the neural microenvironment on prostate cancer. Prostate. 2018 Feb; 78(2):128-139.Prostate2017-11-13T00:00:002017Influence of the neural microenvironment on prostate cancer.23462601Ayala G, Frolov A, Ittman M, Mohammed S, LeBlanc M, Falcon S, Rowley D, Etzioni RAnnals of clinical and laboratory scienceBiological correlates of biochemical recurrence free survival using multiple markers in a large tissue microarray cohort. Ann Clin Lab Sci. 2013; 43(1):11-21.Ann Clin Lab Sci2013-01-01T00:00:002013Biological correlates of biochemical recurrence free survival using multiple markers in a large tissue microarray cohort.23576558Yang F, Zhang Y, Ressler SJ, Ittmann MM, Ayala GE, Dang TD, Wang F, Rowley DRCancer researchFGFR1 is essential for prostate cancer progression and metastasis. Cancer Res. 2013 Jun 15; 73(12):3716-24.Cancer Res2013-04-10T00:00:002013FGFR1 is essential for prostate cancer progression and metastasis.true1ProfessorProfessorD011467Anatomy28510800.656645ProstateD016212Chemicals & Drugs49911310.642492Transforming Growth Factor betaD011944Chemicals & Drugs2908750.646115Receptors, AndrogenD011471Disorders75057370.293776Prostatic NeoplasmsD017154Anatomy3488230.732607Stromal CellsAuthorship 9160781230423299Wang H, Tian L, Liu J, Goldstein A, Bado I, Zhang W, Arenkiel BR, Li Z, Yang M, Du S, Zhao H, Rowley DR, Wong STC, Gugala Z, Zhang XHCancer cellThe Osteogenic Niche Is a Calcium Reservoir of Bone Micrometastases and Confers Unexpected Therapeutic Vulnerability. Cancer Cell. 2018 11 12; 34(5):823-839.e7.Cancer Cell2018-11-12T00:00:002018The Osteogenic Niche Is a Calcium Reservoir of Bone Micrometastases and Confers Unexpected Therapeutic Vulnerability.1989-03-31NIHROWLEY, DAVID R1986-04-01ANDROGEN REGULATED GROWTH FACTORS FROM PROSTATE STROMAR23DK0358971990-08-31NIHROWLEY, DAVID R1987-09-30GROWTH FACTORS FROM FETAL UROGENITAL SINUSR01DK0397792016-08-31NIHROWLEY, DAVID R2010-09-01Interleukin-8 Induced Biology in Benign Prostatic HyperplasiaR01DK0832932015-08-31NIHPIENTA, KENNETH J.2010-09-07Reactive Stroma and Tumor Associated Macrophages in Prostate Cancer ProgressionU01CA1430552015-07-31NIHROWLEY, DAVID R1992-09-30Mesenchymal Derived Growth Factors in Prostatic CancerR01CA0580932012-08-31NIHROWLEY, DAVID R2006-09-25Co-evolution of the Reactive Microenvironment in Prostate Cancer ProgressionU54CA1265682004-08-31NIHROWLEY, DAVID R2003-09-302003 AUA/SBUR Summer Research Conference-Prostate GrowthR13DK0650362023-08-31NIHROWLEY, DAVID R2018-09-05Osteogenic Niche Biology in Progression and Endocrine Resistance of Bone MetastasesR01CA2219462010-08-31NIHROWLEY, DAVID R2009-09-28Interleukin-8 Induced Biology in Benign Prostatic HyperplasiaR56DK0832932007-06-30NIHROWLEY, DAVID R1992-09-30STROMAL GROWTH FACTORS IN BENIGN PROSTATIC HYPERPLASIAR01DK045909Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorCo-Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorDepartment of DermatologyDepartment of Molecular & Cellular BiologyDepartment of Pathology & ImmunologyDepartment of UrologyUrologyDermatologyMolecular & Cellular BiologyPathologyBaylor College of MedicineFENGYANGFENG YANG39.09225730000000-77.20961730000000124YANG, FENGAssociate ProfessorTHOMASWHEELERTHOMAS WHEELER1.28122440000000103.837482800000002555WHEELER, THOMASDistinguished Emeritus ProfessorCAROLYNSMITHCAROLYN SMITH0.000000000000000.000000000000002606SMITH, CAROLYNProfessorARUNSREEKUMARARUN SREEKUMAR39.09225730000000-77.209617300000001838SREEKUMAR, ARUNProfessorMICHAELLEWISMICHAEL LEWIS0.000000000000000.00000000000000353LEWIS, MICHAELProfessorAuthorship 9422496BERTO'MALLEYBERT O'MALLEY0.000000000000000.000000000000002464O'MALLEY, BERTDistinguished Service Professor30865488Miles B, Ittmann M, Wheeler T, Sayeeduddin M, Cubilla A, Rowley D, Bu P, Ding Y, Gao Y, Lee M, Ayala GEArchives of pathology & laboratory medicineMoving Beyond Gleason Scoring. Arch Pathol Lab Med. 2019 05; 143(5):565-570.Arch Pathol Lab Med2019-03-13T00:00:002019Moving Beyond Gleason Scoring.MICHAELITTMANNMICHAEL ITTMANN0.000000000000000.000000000000002694ITTMANN, MICHAELProfessor4.311940.00240684540research areas2.506280.0041202148coauthor of70.628214.756960similar to11114selected publicationsIRINAAGOULNIKIRINA AGOULNIK0.000000000000000.000000000000003486AGOULNIK, IRINAAdjunct Associate ProfessorXINXIEXIN XIE0.000000000000000.00000000000000653XIE, XINAdjunct Assistant ProfessorAuthorship 126694923732988Kakarla S, Chow KK, Mata M, Shaffer DR, Song XT, Wu MF, Liu H, Wang LL, Rowley DR, Pfizenmaier K, Gottschalk SMolecular therapy : the journal of the American Society of Gene TherapyAntitumor effects of chimeric receptor engineered human T cells directed to tumor stroma. Mol Ther. 2013 Aug; 21(8):1611-20.Mol Ther2013-06-04T00:00:002013Antitumor effects of chimeric receptor engineered human T cells directed to tumor stroma.Authorship 9471051631086186Lee YC, Kurtova AV, Xiao J, Nikolos F, Hayashi K, Tramel Z, Jain A, Chen F, Chokshi M, Lee C, Bao G, Zhang X, Shen J, Mo Q, Jung SY, Rowley D, Chan KSNature communicationsCollagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung. Nat Commun. 2019 05 13; 10(1):2131.Nat Commun2019-05-13T00:00:002019Collagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung.Authorship 9520421631308490Arnold JM, Gu F, Ambati CR, Rasaily U, Ramirez-Pena E, Joseph R, Manikkam M, San Martin R, Charles C, Pan Y, Chatterjee SS, Den Hollander P, Zhang W, Nagi C, Sikora AG, Rowley D, Putluri N, Zhang XH, Karanam B, Mani SA, Sreekumar AOncogeneUDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression. Oncogene. 2020 04; 39(15):3089-3101.Oncogene2019-07-15T00:00:002019UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression.Authorship 9529971431363002Beltran H, Hruszkewycz A, Scher HI, Hildesheim J, Isaacs J, Yu EY, Kelly K, Lin D, Dicker A, Arnold J, Hecht T, Wicha M, Sears R, Rowley D, White R, Gulley JL, Lee J, Diaz Meco M, Small EJ, Shen M, Knudsen K, Goodrich DW, Lotan T, Zoubeidi A, Sawyers CL, Rudin CM, Loda M, Thompson T, Rubin MA, Tawab-Amiri A, Dahut W, Nelson PSClinical cancer research : an official journal of the American Association for Cancer ResearchThe Role of Lineage Plasticity in Prostate Cancer Therapy Resistance. Clin Cancer Res. 2019 12 01; 25(23):6916-6924.Clin Cancer Res2019-07-30T00:00:002019The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance.true1ProfessorProfessortrue1Postdoc Fellows and AssociatesPostdoc Fellows and Associatestrue1Distinguished Service ProfessorDistinguished Service Professortrue1ProfessorProfessorRintuThomasRintu Thomas15066Thomas, RintuPostdoc Fellows and AssociatesAuthorship 109094671Postdoc Fellows and AssociatesPostDocAuthorship 9800921632214199Arnold JM, Gu F, Ambati CR, Rasaily U, Ramirez-Pena E, Joseph R, Manikkam M, Martin RS, Charles C, Pan Y, Chatterjee SS, Den Hollander P, Zhang W, Nagi C, Sikora AG, Rowley D, Putluri N, Zhang XH, Karanam B, Mani SA, Sreekumar AOncogeneCorrection: UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression. Oncogene. 2020 Apr; 39(15):3226-3228.Oncogene2020-04-01T00:00:002020Correction: UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression.true1Adjunct Associate ProfessorAdjunct Associate ProfessorAuthorship 98082512355376Rowley DI, Jain ASJournal of the Royal College of Surgeons of EdinburghAmputation surgery--a plea for caution. J R Coll Surg Edinb. 1990 Apr; 35(2):112.J R Coll Surg Edinb1990-04-01T00:00:001990Amputation surgery--a plea for caution.Authorship 1178367true1Adjunct Assistant ProfessorAdjunct Assistant ProfessorAuthorship 1005602633230244Guha P, Gardell J, Rabinowitz B, Lopes M, DaSilva NA, Rowley D, Katz SCOncogeneMonocytic and granulocytic myeloid-derived suppressor cell plasticity and differentiation are organ-specific. Oncogene. 2021 01; 40(3):693-704.Oncogene2020-11-23T00:00:002020Monocytic and granulocytic myeloid-derived suppressor cell plasticity and differentiation are organ-specific.Authorship 1007953433378361Spencer Clinton JL, Tran LL, Vogt MB, Rowley DR, Kimata JT, Rico-Hesse RPloS oneIP-10 and CXCR3 signaling inhibit Zika virus replication in human prostate cells. PLoS One. 2020; 15(12):e0244587.PLoS One2020-12-30T00:00:002020IP-10 and CXCR3 signaling inhibit Zika virus replication in human prostate cells.Authorship 10115491133586682Shen T, Wang W, Zhou W, Coleman I, Cai Q, Dong B, Ittmann MM, Creighton CJ, Bian Y, Meng Y, Rowley DR, Nelson PS, Moore DD, Yang FThe Journal of clinical investigationMAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT. J Clin Invest. 2021 02 15; 131(4).J Clin Invest2021-02-15T00:00:002021MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT.Authorship 1217014Authorship 1173764Authorship 125142Authorship 1029716434520582Tran LL, Dang T, Thomas R, Rowley DRStem cells (Dayton, Ohio)ELF3 mediates IL-1a induced differentiation of mesenchymal stem cells to inflammatory iCAFs. Stem Cells. 2021 12; 39(12):1766-1777.Stem Cells2021-10-07T00:00:002021ELF3 mediates IL-1a induced differentiation of mesenchymal stem cells to inflammatory iCAFs.Authorship 116889Authorship 1178731Authorship 10406762135176252Ruder S, Gao Y, Ding Y, Bu P, Miles B, De Marzo A, Wheeler T, McKenney JK, Auman H, Fazli L, Simko J, Hurtado-Coll A, Troyer DA, Carroll PR, Gleave M, Platz E, Trock B, Han M, Sayeeduddin M, True LD, Rowley D, Lin DW, Nelson PS, Thompson IM, Feng Z, Wei W, Brooks JD, Ittmann M, Lee M, Ayala GHuman pathologyDevelopment and validation of a quantitative reactive stroma biomarker (qRS) for prostate cancer prognosis. Hum Pathol. 2022 04; 122:84-91.Hum Pathol2022-02-15T00:00:002022Development and validation of a quantitative reactive stroma biomarker (qRS) for prostate cancer prognosis.Authorship 1372929Authorship 137400224097862Ding Y, He D, Florentin D, Frolov A, Hilsenbeck S, Ittmann M, Kadmon D, Miles B, Rowley D, Ayala GClinical cancer research : an official journal of the American Association for Cancer ResearchSemaphorin 4F as a critical regulator of neuroepithelial interactions and a biomarker of aggressive prostate cancer. Clin Cancer Res. 2013 Nov 15; 19(22):6101-11.Clin Cancer Res2013-10-04T00:00:002013Semaphorin 4F as a critical regulator of neuroepithelial interactions and a biomarker of aggressive prostate cancer.24150235Dakhova O, Rowley D, Ittmann MClinical cancer research : an official journal of the American Association for Cancer ResearchGenes upregulated in prostate cancer reactive stroma promote prostate cancer progression in vivo. Clin Cancer Res. 2014 Jan 01; 20(1):100-9.Clin Cancer Res2013-10-22T00:00:002013Genes upregulated in prostate cancer reactive stroma promote prostate cancer progression in vivo.Authorship 120758935948987Thomas R, Jerome JM, Dang TD, Souto EP, Mallam JN, Rowley DRCell communication and signaling : CCSAndrogen receptor variant-7 regulation by tenascin-c induced src activation. Cell Commun Signal. 2022 08 10; 20(1):119.Cell Commun Signal2022-08-10T00:00:002022Androgen receptor variant-7 regulation by tenascin-c induced src activation.35954173Ravindran A, Krieger KL, Kaushik AK, Hovington H, Mehdi S, Piyarathna DWB, Putluri V, Basil P, Rasaily U, Gu F, Dang T, Choi JM, Sonavane R, Jung SY, Wang L, Mehra R, Weigel NL, Putluri N, Rowley DR, Palapattu GS, Guillemette C, Lacombe L, L?vesque ?, Sreekumar ACellsUridine Diphosphate Glucuronosyl Transferase 2B28 (UGT2B28) Promotes Tumor Progression and Is Elevated in African American Prostate Cancer Patients. Cells. 2022 07 29; 11(15).Cells2022-07-29T00:00:002022Uridine Diphosphate Glucuronosyl Transferase 2B28 (UGT2B28) Promotes Tumor Progression and Is Elevated in African American Prostate Cancer Patients.Authorship 106288319Authorship 10628686Authorship 10669517Authorship 10668731Authorship 10669082Authorship 10668204Authorship 106688442112981Ward PL, Koeppen HK, Hurteau T, Rowley DA, Schreiber HCancer researchMajor histocompatibility complex class I and unique antigen expression by murine tumors that escaped from CD8+ T-cell-dependent surveillance. Cancer Res. 1990 Jul 01; 50(13):3851-8.Cancer Res1990-07-01T00:00:001990Major histocompatibility complex class I and unique antigen expression by murine tumors that escaped from CD8+ T-cell-dependent surveillance.2137615Torre-Amione G, Beauchamp RD, Koeppen H, Park BH, Schreiber H, Moses HL, Rowley DAProceedings of the National Academy of Sciences of the United States of AmericaA highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance. Proc Natl Acad Sci U S A. 1990 Feb; 87(4):1486-90.Proc Natl Acad Sci U S A1990-02-01T00:00:001990A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance.1309851Singh S, Ross SR, Acena M, Rowley DA, Schreiber HThe Journal of experimental medicineStroma is critical for preventing or permitting immunological destruction of antigenic cancer cells. J Exp Med. 1992 Jan 01; 175(1):139-46.J Exp Med1992-01-01T00:00:001992Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells.9576624Rowley DA, Stach RMInternational immunologyB lymphocytes secreting IgG linked to latent transforming growth factor-beta prevent primary cytolytic T lymphocyte responses. Int Immunol. 1998 Mar; 10(3):355-63.Int Immunol1998-03-01T00:00:001998B lymphocytes secreting IgG linked to latent transforming growth factor-beta prevent primary cytolytic T lymphocyte responses.8350058Stach RM, Rowley DAThe Journal of experimental medicineA first or dominant immunization. II. Induced immunoglobulin carries transforming growth factor beta and suppresses cytolytic T cell responses to unrelated alloantigens. J Exp Med. 1993 Sep 01; 178(3):841-52.J Exp Med1993-09-01T00:00:001993A first or dominant immunization. II. Induced immunoglobulin carries transforming growth factor beta and suppresses cytolytic T cell responses to unrelated alloantigens.true1ProfessorProfessortrue1ProfessorProfessor2ProfessorProfessor3ProfessorProfessortrue1Associate ProfessorAssociate ProfessorAuthorship 10858621638148936Charles C, Lloyd SM, Piyarathna DWB, Gohlke J, Rasaily U, Putluri V, Simons BW, Zaslavsky A, Nallandhighal S, Michailidis G, Palanisamy N, Navone N, Jones JA, Ittmann MM, Putluri N, Rowley DR, Salami SS, Palapattu GS, Sreekumar AAmerican journal of clinical and experimental urologyRole of adenosine deaminase in prostate cancer progression. Am J Clin Exp Urol. 2023; 11(6):594-612.Am J Clin Exp Urol2023-12-15T00:00:002023Role of adenosine deaminase in prostate cancer progression.true1Distinguished Emeritus ProfessorDistinguished Emeritus Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 292796Authorship 253667Authorship 22353Authorship 256603Authorship 228163Authorship 252822Authorship 265793Authorship 378153Authorship 272343Authorship 390484Authorship 390767Authorship 27933Authorship 28903Authorship 320082Authorship 1420321224305876Carstens JL, Shahi P, Van Tsang S, Smith B, Creighton CJ, Zhang Y, Seamans A, Seethammagari M, Vedula I, Levitt JM, Ittmann MM, Rowley DR, Spencer DMCancer researchFGFR1-WNT-TGF-? signaling in prostate cancer mouse models recapitulates human reactive stroma. Cancer Res. 2014 Jan 15; 74(2):609-20.Cancer Res2013-12-04T00:00:002013FGFR1-WNT-TGF-? signaling in prostate cancer mouse models recapitulates human reactive stroma.Authorship 468828Authorship 357944Authorship 394966Authorship 398795Authorship 406722Authorship 14563812Authorship 58989624713391San Martin R, Barron DA, Tuxhorn JA, Ressler SJ, Hayward SW, Shen X, Laucirica R, Wheeler TM, Gutierrez C, Ayala GE, Ittmann M, Rowley DRThe American journal of pathologyRecruitment of CD34(+) fibroblasts in tumor-associated reactive stroma: the reactive microvasculature hypothesis. Am J Pathol. 2014 Jun; 184(6):1860-70.Am J Pathol2014-04-05T00:00:002014Recruitment of CD34(+) fibroblasts in tumor-associated reactive stroma: the reactive microvasculature hypothesis.Authorship 4138612Authorship 43533Authorship 596916Authorship 66887Authorship 709113Authorship 529971Authorship 536284Authorship 557488Authorship 568319Authorship 57308625219356Ressler SJ, Dang TD, Wu SM, Tse DY, Gilbert BE, Vyakarnam A, Yang F, Schauer IG, Barron DA, Rowley DRThe American journal of pathologyWFDC1 is a key modulator of inflammatory and wound repair responses. Am J Pathol. 2014 Nov; 184(11):2951-64.Am J Pathol2014-09-16T00:00:002014WFDC1 is a key modulator of inflammatory and wound repair responses.Authorship 624781025313057Kim W, Barron DA, San Martin R, Chan KS, Tran LL, Yang F, Ressler SJ, Rowley DRProceedings of the National Academy of Sciences of the United States of AmericaRUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16389-94.Proc Natl Acad Sci U S A2014-10-13T00:00:002014RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation.Authorship 153073125314074Rowley DRCancer cellReprogramming the tumor stroma: a new paradigm. Cancer Cell. 2014 Oct 13; 26(4):451-2.Cancer Cell2014-10-13T00:00:002014Reprogramming the tumor stroma: a new paradigm.Authorship 9291Authorship 668567Authorship 153510825333263Yang F, Chen Y, Shen T, Guo D, Dakhova O, Ittmann MM, Creighton CJ, Zhang Y, Dang TD, Rowley DROncotargetStromal TGF-? signaling induces AR activation in prostate cancer. Oncotarget. 2014 Nov 15; 5(21):10854-69.Oncotarget2014-11-15T00:00:002014Stromal TGF-? signaling induces AR activation in prostate cancer.25374926Strand DW, Liang YY, Yang F, Barron DA, Ressler SJ, Schauer IG, Feng XH, Rowley DRAmerican journal of clinical and experimental urologyTGF-? induction of FGF-2 expression in stromal cells requires integrated smad3 and MAPK pathways. Am J Clin Exp Urol. 2014; 2(3):239-48.Am J Clin Exp Urol2014-10-02T00:00:002014TGF-? induction of FGF-2 expression in stromal cells requires integrated smad3 and MAPK pathways.Authorship 15356810Authorship 1535728Authorship 705125Authorship 15360510Authorship 789243