Connection

Co-Authors

This is a "connection" page, showing publications co-authored by BERT O'MALLEY and JIANMING XU.
Connection Strength

2.832
  1. Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nat Rev Cancer. 2009 Sep; 9(9):615-30.
    View in: PubMed
    Score: 0.348
  2. Molecular mechanisms and cellular biology of the steroid receptor coactivator (SRC) family in steroid receptor function. Rev Endocr Metab Disord. 2002 Sep; 3(3):185-92.
    View in: PubMed
    Score: 0.214
  3. The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6379-84.
    View in: PubMed
    Score: 0.184
  4. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science. 1998 Mar 20; 279(5358):1922-5.
    View in: PubMed
    Score: 0.157
  5. The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12195-9.
    View in: PubMed
    Score: 0.143
  6. SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart. PLoS One. 2012; 7(12):e53395.
    View in: PubMed
    Score: 0.110
  7. Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1. Oncogene. 2011 Oct 20; 30(42):4350-64.
    View in: PubMed
    Score: 0.098
  8. The coactivator SRC-1 is an essential coordinator of hepatic glucose production. Cell Metab. 2010 Dec 01; 12(6):606-18.
    View in: PubMed
    Score: 0.095
  9. Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proc Natl Acad Sci U S A. 2009 Jan 06; 106(1):151-6.
    View in: PubMed
    Score: 0.083
  10. Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science. 2008 Nov 28; 322(5906):1395-9.
    View in: PubMed
    Score: 0.083
  11. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol Cell Biol. 2008 Oct; 28(19):5937-50.
    View in: PubMed
    Score: 0.081
  12. An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Mol Cell. 2007 Mar 09; 25(5):765-78.
    View in: PubMed
    Score: 0.073
  13. Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16716-21.
    View in: PubMed
    Score: 0.071
  14. Stimulation of steroid receptor coactivator-3 (SRC-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3. Mol Endocrinol. 2006 Dec; 20(12):3105-19.
    View in: PubMed
    Score: 0.071
  15. Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice. Mol Cell Biol. 2005 Sep; 25(18):8150-65.
    View in: PubMed
    Score: 0.066
  16. Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Res. 2005 Sep 01; 65(17):7993-8002.
    View in: PubMed
    Score: 0.066
  17. Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol. 2006 Jan; 20(1):45-55.
    View in: PubMed
    Score: 0.066
  18. Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9487-92.
    View in: PubMed
    Score: 0.065
  19. Nuclear receptor coregulators are new players in nervous system development and function. Mol Neurobiol. 2004 Dec; 30(3):307-25.
    View in: PubMed
    Score: 0.063
  20. Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4453-8.
    View in: PubMed
    Score: 0.060
  21. AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice. Cancer Res. 2004 Mar 01; 64(5):1875-85.
    View in: PubMed
    Score: 0.059
  22. SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells. J Neurosci. 2003 Jan 01; 23(1):213-22.
    View in: PubMed
    Score: 0.055
  23. Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. J Steroid Biochem Mol Biol. 2002 Dec; 83(1-5):3-14.
    View in: PubMed
    Score: 0.055
  24. Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol. 2002 May; 22(10):3549-61.
    View in: PubMed
    Score: 0.052
  25. Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions. J Steroid Biochem Mol Biol. 1999 Apr-Jun; 69(1-6):3-12.
    View in: PubMed
    Score: 0.042
  26. Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family. Mol Endocrinol. 2013 Feb; 27(2):366-80.
    View in: PubMed
    Score: 0.027
  27. Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. Cell Metab. 2012 May 02; 15(5):752-63.
    View in: PubMed
    Score: 0.026
  28. A SNP in steroid receptor coactivator-1 disrupts a GSK3? phosphorylation site and is associated with altered tamoxifen response in bone. Mol Endocrinol. 2012 Feb; 26(2):220-7.
    View in: PubMed
    Score: 0.025
  29. Repressor of estrogen receptor activity (REA) is essential for mammary gland morphogenesis and functional activities: studies in conditional knockout mice. Endocrinology. 2011 Nov; 152(11):4336-49.
    View in: PubMed
    Score: 0.025
  30. Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):11122-7.
    View in: PubMed
    Score: 0.023
  31. The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Res. 2008 May 15; 68(10):3697-706.
    View in: PubMed
    Score: 0.020
  32. The skeletal response to estrogen is impaired in female but not in male steroid receptor coactivator (SRC)-1 knock out mice. Bone. 2008 Feb; 42(2):414-21.
    View in: PubMed
    Score: 0.019
  33. Steroid receptor coactivator-1-deficient mice exhibit altered hypothalamic-pituitary-adrenal axis function. Endocrinology. 2006 Mar; 147(3):1322-32.
    View in: PubMed
    Score: 0.017
  34. Dual functions of the steroid hormone receptor coactivator 3 in modulating resistance to thyroid hormone. Mol Cell Biol. 2005 Sep; 25(17):7687-95.
    View in: PubMed
    Score: 0.016
  35. Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo. Mol Cell Biol. 2005 Mar; 25(5):1989-99.
    View in: PubMed
    Score: 0.016
  36. Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD. J Biol Chem. 2005 Feb 04; 280(5):3129-37.
    View in: PubMed
    Score: 0.016
  37. Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology. 2004 Feb; 145(2):913-21.
    View in: PubMed
    Score: 0.014
  38. Modulation by steroid receptor coactivator-1 of target-tissue responsiveness in resistance to thyroid hormone. Endocrinology. 2003 Sep; 144(9):4144-53.
    View in: PubMed
    Score: 0.014
  39. Steroid receptor coactivator-1 is not required for androgen-mediated sexual differentiation of spinal motoneurons. Neuroendocrinology. 2003 Jul; 78(1):45-51.
    View in: PubMed
    Score: 0.014
  40. Regulation of expression of thyroid hormone receptor isoforms and coactivators in liver and heart by thyroid hormone. Mol Cell Endocrinol. 2003 May 30; 203(1-2):65-75.
    View in: PubMed
    Score: 0.014
  41. Thyroid hormone receptor-specific interactions with steroid receptor coactivator-1 in the pituitary. Mol Endocrinol. 2003 May; 17(5):882-94.
    View in: PubMed
    Score: 0.014
  42. Specificity of thyroid hormone receptor subtype and steroid receptor coactivator-1 on thyroid hormone action. Am J Physiol Endocrinol Metab. 2003 Jan; 284(1):E36-46.
    View in: PubMed
    Score: 0.013
  43. Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo. Endocrinology. 2002 Apr; 143(4):1346-52.
    View in: PubMed
    Score: 0.013
  44. Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency. Endocrinology. 2002 Apr; 143(4):1554-7.
    View in: PubMed
    Score: 0.013
  45. Activation of PPARgamma coactivator-1 through transcription factor docking. Science. 1999 Nov 12; 286(5443):1368-71.
    View in: PubMed
    Score: 0.011
  46. Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone. EMBO J. 1999 Apr 01; 18(7):1900-4.
    View in: PubMed
    Score: 0.011
  47. Positive and negative regulation of gene expression in eukaryotic cells with an inducible transcriptional regulator. Gene Ther. 1997 May; 4(5):432-41.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.