Connection

Co-Authors

This is a "connection" page, showing publications co-authored by BERT O'MALLEY and SOPHIA TSAI.
Connection Strength

4.129
  1. SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription. Mol Cell. 2018 05 17; 70(4):679-694.e7.
    View in: PubMed
    Score: 0.156
  2. Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. Nature. 2018 04; 556(7700):249-254.
    View in: PubMed
    Score: 0.155
  3. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017 09 01; 292(35):14456-14472.
    View in: PubMed
    Score: 0.148
  4. Estrogen Receptor ? Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 2015 Nov 05; 163(4):960-74.
    View in: PubMed
    Score: 0.131
  5. CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-a-Gabpa and stress-induced adaptive responses via NF-?B-cMYC. PLoS Genet. 2015 Apr; 11(4):e1005116.
    View in: PubMed
    Score: 0.126
  6. E2/Estrogen receptor/sjogren syndrome-associated autoantigen relieves coactivator activator-induced G1/S arrest to promote breast tumorigenicity. Mol Cell Biol. 2014 May; 34(9):1670-81.
    View in: PubMed
    Score: 0.117
  7. Proteomic analysis of coregulators bound to ERa on DNA and nucleosomes reveals coregulator dynamics. Mol Cell. 2013 Jul 25; 51(2):185-99.
    View in: PubMed
    Score: 0.112
  8. ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion. J Clin Invest. 2012 May; 122(5):1869-80.
    View in: PubMed
    Score: 0.103
  9. Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene. Mol Endocrinol. 2010 May; 24(5):1090-105.
    View in: PubMed
    Score: 0.089
  10. SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell. 2010 Feb 12; 37(3):321-32.
    View in: PubMed
    Score: 0.088
  11. Biochemical control of CARM1 enzymatic activity by phosphorylation. J Biol Chem. 2009 Dec 25; 284(52):36167-36174.
    View in: PubMed
    Score: 0.086
  12. Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol. 2009 Jun; 23(6):740-6.
    View in: PubMed
    Score: 0.084
  13. Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements. Cell. 1989 May 05; 57(3):443-8.
    View in: PubMed
    Score: 0.084
  14. Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation. Cell. 1988 Oct 21; 55(2):361-9.
    View in: PubMed
    Score: 0.081
  15. Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis. Cancer Res. 2008 Oct 01; 68(19):7887-96.
    View in: PubMed
    Score: 0.080
  16. Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. Mol Cell. 2008 Sep 26; 31(6):835-49.
    View in: PubMed
    Score: 0.080
  17. Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell. 2008 Feb 29; 29(4):465-76.
    View in: PubMed
    Score: 0.077
  18. Distinct temporal and spatial activities of RU486 on progesterone receptor function in reproductive organs of ovariectomized mice. Endocrinology. 2007 May; 148(5):2471-86.
    View in: PubMed
    Score: 0.072
  19. Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover. Mol Cell Biol. 2007 Feb; 27(4):1296-308.
    View in: PubMed
    Score: 0.071
  20. The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell. 2006 Jan 27; 124(2):381-92.
    View in: PubMed
    Score: 0.067
  21. Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol. 2005 Nov; 25(21):9687-99.
    View in: PubMed
    Score: 0.066
  22. Regulatable atrial natriuretic peptide gene therapy for hypertension. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):13789-94.
    View in: PubMed
    Score: 0.065
  23. Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice. Mol Cell Biol. 2005 Sep; 25(18):8150-65.
    View in: PubMed
    Score: 0.065
  24. Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol. 2006 Jan; 20(1):45-55.
    View in: PubMed
    Score: 0.065
  25. Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9487-92.
    View in: PubMed
    Score: 0.064
  26. Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell. 2004 Sep 24; 15(6):937-49.
    View in: PubMed
    Score: 0.061
  27. Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins. Mol Cell Biol. 2004 Jan; 24(1):14-24.
    View in: PubMed
    Score: 0.058
  28. Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol. 2003 Jun; 23(11):3763-73.
    View in: PubMed
    Score: 0.055
  29. Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):7940-4.
    View in: PubMed
    Score: 0.052
  30. Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol. 2002 May; 22(10):3549-61.
    View in: PubMed
    Score: 0.051
  31. Ligand-inducible transgene regulation for gene therapy. Methods Enzymol. 2002; 346:551-61.
    View in: PubMed
    Score: 0.050
  32. Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12426-31.
    View in: PubMed
    Score: 0.050
  33. An antiprogestin regulable gene switch for induction of gene expression in vivo. Adv Pharmacol. 2000; 47:343-55.
    View in: PubMed
    Score: 0.044
  34. Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9485-90.
    View in: PubMed
    Score: 0.043
  35. A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 1999 Apr 02; 97(1):17-27.
    View in: PubMed
    Score: 0.042
  36. Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions. J Steroid Biochem Mol Biol. 1999 Apr-Jun; 69(1-6):3-12.
    View in: PubMed
    Score: 0.042
  37. The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol Cell Biol. 1999 Feb; 19(2):1182-9.
    View in: PubMed
    Score: 0.041
  38. Adenovirus-mediated regulable target gene expression in vivo. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):355-60.
    View in: PubMed
    Score: 0.041
  39. Distinct steady-state nuclear receptor coregulator complexes exist in vivo. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11697-702.
    View in: PubMed
    Score: 0.040
  40. The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors. J Biol Chem. 1998 May 15; 273(20):12101-8.
    View in: PubMed
    Score: 0.039
  41. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science. 1998 Mar 20; 279(5358):1922-5.
    View in: PubMed
    Score: 0.039
  42. A regulatory system for target gene expression. Front Biosci. 1998 Jan 01; 3:c1-7.
    View in: PubMed
    Score: 0.038
  43. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature. 1997 Sep 11; 389(6647):194-8.
    View in: PubMed
    Score: 0.037
  44. Steroid receptor induction of gene transcription: a two-step model. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):7879-84.
    View in: PubMed
    Score: 0.037
  45. Positive and negative regulation of gene expression in eukaryotic cells with an inducible transcriptional regulator. Gene Ther. 1997 May; 4(5):432-41.
    View in: PubMed
    Score: 0.036
  46. Ligand-inducible and liver-specific target gene expression in transgenic mice. Nat Biotechnol. 1997 Mar; 15(3):239-43.
    View in: PubMed
    Score: 0.036
  47. Inducible system designed for future gene therapy. Methods Mol Biol. 1997; 63:401-13.
    View in: PubMed
    Score: 0.036
  48. The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12195-9.
    View in: PubMed
    Score: 0.035
  49. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science. 1995 Nov 24; 270(5240):1354-7.
    View in: PubMed
    Score: 0.033
  50. Correction: Perturbing the Cellular Levels of Steroid Receptor Coactivator-2 Impairs Murine Endometrial Function. PLoS One. 2015; 10(11):e0143652.
    View in: PubMed
    Score: 0.033
  51. The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing. Mol Cell Biol. 1995 Jan; 15(1):76-86.
    View in: PubMed
    Score: 0.031
  52. A regulatory system for use in gene transfer. Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17):8180-4.
    View in: PubMed
    Score: 0.030
  53. Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function. PLoS One. 2014; 9(6):e98664.
    View in: PubMed
    Score: 0.030
  54. Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain. Mol Endocrinol. 1993 Oct; 7(10):1266-74.
    View in: PubMed
    Score: 0.028
  55. Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):11750-4.
    View in: PubMed
    Score: 0.027
  56. Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation. J Biol Chem. 1992 Sep 25; 267(27):19513-20.
    View in: PubMed
    Score: 0.026
  57. Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II). J Biol Chem. 1992 Sep 05; 267(25):17617-23.
    View in: PubMed
    Score: 0.026
  58. Analysis of the mechanism of steroid hormone receptor-dependent gene activation in cell-free systems. Endocr Rev. 1992 Aug; 13(3):525-35.
    View in: PubMed
    Score: 0.026
  59. Ligand and DNA-dependent phosphorylation of human progesterone receptor in vitro. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):2664-8.
    View in: PubMed
    Score: 0.026
  60. Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70. Mol Cell Biol. 1991 Oct; 11(10):4998-5004.
    View in: PubMed
    Score: 0.025
  61. Synergism between steroid response and promoter elements during cell-free transcription. J Biol Chem. 1991 Mar 25; 266(9):5905-10.
    View in: PubMed
    Score: 0.024
  62. Molecular mechanism of action of a steroid hormone receptor. Recent Prog Horm Res. 1991; 47:1-24; discussion 24-6.
    View in: PubMed
    Score: 0.023
  63. Mechanism of estrogen receptor-dependent transcription in a cell-free system. Mol Cell Biol. 1990 Dec; 10(12):6607-12.
    View in: PubMed
    Score: 0.023
  64. Recombinant human glucocorticoid receptor induces transcription of hormone response genes in vitro. J Biol Chem. 1990 Oct 05; 265(28):17055-61.
    View in: PubMed
    Score: 0.023
  65. Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription. Nature. 1990 Jun 07; 345(6275):547-50.
    View in: PubMed
    Score: 0.023
  66. Regulation of in vitro transcription by progesterone receptor. Characterization and kinetic studies. J Biol Chem. 1990 Mar 25; 265(9):5129-34.
    View in: PubMed
    Score: 0.022
  67. The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex. Cell. 1990 Jan 26; 60(2):247-57.
    View in: PubMed
    Score: 0.022
  68. Multiple protein binding sites within the ovalbumin gene 5'-flanking region: isolation and characterization of sequence-specific binding proteins. Nucleic Acids Res. 1989 Aug 25; 17(16):6693-711.
    View in: PubMed
    Score: 0.021
  69. COUP transcription factor is a member of the steroid receptor superfamily. Nature. 1989 Jul 13; 340(6229):163-6.
    View in: PubMed
    Score: 0.021
  70. Specific binding of estrogen receptor to the estrogen response element. Mol Cell Biol. 1989 Jan; 9(1):43-9.
    View in: PubMed
    Score: 0.020
  71. Steroid hormone-dependent interaction of human progesterone receptor with its target enhancer element. Mol Endocrinol. 1988 Dec; 2(12):1221-9.
    View in: PubMed
    Score: 0.020
  72. The studies of COUP transcription factor from HeLa cells: purification and partial characterization. Prog Clin Biol Res. 1988; 284:37-51.
    View in: PubMed
    Score: 0.019
  73. Cooperative interactions of steroid hormone receptors with their cognate response elements. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 2:829-33.
    View in: PubMed
    Score: 0.019
  74. Purification and characterization of chicken ovalbumin gene upstream promoter transcription factor from homologous oviduct cells. Mol Cell Biol. 1987 Dec; 7(12):4151-8.
    View in: PubMed
    Score: 0.019
  75. Purification and characterization of chicken ovalbumin upstream promoter transcription factor from HeLa cells. J Biol Chem. 1987 Nov 25; 262(33):16080-6.
    View in: PubMed
    Score: 0.019
  76. Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17868-73.
    View in: PubMed
    Score: 0.018
  77. The epidermis as a bioreactor: topically regulated cutaneous delivery into the circulation. Hum Gene Ther. 2002 Jun 10; 13(9):1075-80.
    View in: PubMed
    Score: 0.013
  78. Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT). Mol Endocrinol. 1997 Jun; 11(6):714-24.
    View in: PubMed
    Score: 0.009
  79. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Prog Horm Res. 1997; 52:141-64; discussion 164-5.
    View in: PubMed
    Score: 0.009
  80. Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region. Mol Cell Biol. 1995 Jan; 15(1):255-63.
    View in: PubMed
    Score: 0.008
  81. Mechanisms for synergistic activation of thyroid hormone receptor and retinoid X receptor on different response elements. J Biol Chem. 1994 Dec 16; 269(50):31436-42.
    View in: PubMed
    Score: 0.008
  82. Detection of potential ligands for nuclear receptors in cellular extracts. Endocrinology. 1994 Jul; 135(1):248-52.
    View in: PubMed
    Score: 0.007
  83. Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor. J Steroid Biochem Mol Biol. 1993 Dec; 46(6):643-61.
    View in: PubMed
    Score: 0.007
  84. Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors. J Biol Chem. 1993 Feb 25; 268(6):4152-60.
    View in: PubMed
    Score: 0.007
  85. Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):10633-7.
    View in: PubMed
    Score: 0.007
  86. Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Mol Cell Biol. 1992 Sep; 12(9):4153-63.
    View in: PubMed
    Score: 0.007
  87. Hormone activation of baculovirus expressed progesterone receptors. J Biol Chem. 1992 Mar 15; 267(8):5193-8.
    View in: PubMed
    Score: 0.006
  88. Studies on the mechanism of functional cooperativity between progesterone and estrogen receptors. J Biol Chem. 1991 Sep 05; 266(25):16684-90.
    View in: PubMed
    Score: 0.006
  89. Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat. J Virol. 1991 Jun; 65(6):2853-60.
    View in: PubMed
    Score: 0.006
  90. Steroid hormone receptors and in vitro transcription. Bioessays. 1991 Feb; 13(2):73-8.
    View in: PubMed
    Score: 0.006
  91. The COUP-TFs compose a family of functionally related transcription factors. Gene Expr. 1991; 1(3):207-16.
    View in: PubMed
    Score: 0.006
  92. Superactive estrogen receptors. Potent activators of gene expression. J Biol Chem. 1990 Jul 15; 265(20):11517-21.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.