NAGIREDDYPUTLURINAGIREDDY PUTLURI39.09225730000000-77.209617300000001875PUTLURI, NAGIREDDYProfessorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 1087772Authorship 1616882Authorship 162934225664849Dasgupta S, Putluri N, Long W, Zhang B, Wang J, Kaushik AK, Arnold JM, Bhowmik SK, Stashi E, Brennan CA, Rajapakshe K, Coarfa C, Mitsiades N, Ittmann MM, Chinnaiyan AM, Sreekumar A, O'Malley BWThe Journal of clinical investigationCoactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis. J Clin Invest. 2015 Mar 02; 125(3):1174-88.J Clin Invest2015-02-09T00:00:002015Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis.25830341Kang YK, Putluri N, Maity S, Tsimelzon A, Ilkayeva O, Mo Q, Lonard D, Michailidis G, Sreekumar A, Newgard CB, Wang M, Tsai SY, Tsai MJ, O'Malley BWPLoS geneticsCAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-a-Gabpa and stress-induced adaptive responses via NF-?B-cMYC. PLoS Genet. 2015 Apr; 11(4):e1005116.PLoS Genet2015-04-01T00:00:002015CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-a-Gabpa and stress-induced adaptive responses via NF-?B-cMYC.Gynecological Oncology & Reproductive MedicineMD AndersonASHISHKAMATASHISH KAMAT8961KAMAT, ASHISHProfessorCOLIN PDINNEYCOLIN P DINNEY8624DINNEY, COLIN PProfessorANIL KSOODANIL K SOOD9048SOOD, ANIL KProfessorAuthorship 455291Authorship 593271One Baylor PlazaHouston, 77030TXAuthorship 2976566Authorship 2993397Authorship 3000429Authorship 3006875Authorship 305911426152357Zaslavsky AB, Gloeckner-Kalousek A, Adams M, Putluri N, Venghatakrishnan H, Li H, Morgan TM, Feng FY, Tewari M, Sreekumar A, Palapattu GSNeoplasia (New York, N.Y.)Platelet-Synthesized Testosterone in Men with Prostate Cancer Induces Androgen Receptor Signaling. Neoplasia. 2015 Jun; 17(6):490-6.Neoplasia2015-06-01T00:00:002015Platelet-Synthesized Testosterone in Men with Prostate Cancer Induces Androgen Receptor Signaling.26315396Bhowmik SK, Ramirez-Pe?a E, Arnold JM, Putluri V, Sphyris N, Michailidis G, Putluri N, Ambs S, Sreekumar A, Mani SAOncotargetEMT-induced metabolite signature identifies poor clinical outcome. Oncotarget. 2015 Dec 15; 6(40):42651-60.Oncotarget2015-12-15T00:00:002015EMT-induced metabolite signature identifies poor clinical outcome.26378018Shafi AA, Putluri V, Arnold JM, Tsouko E, Maity S, Roberts JM, Coarfa C, Frigo DE, Putluri N, Sreekumar A, Weigel NLOncotargetDifferential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells. Oncotarget. 2015 Oct 13; 6(31):31997-2012.Oncotarget2015-10-13T00:00:002015Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells.26418340Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BWPLoS geneticsCorrection: Acceleration of the Glycolytic Flux by Steroid Receptor Coactivator-2 Is Essential for Endometrial Decidualization. PLoS Genet. 2015 Sep; 11(9):e1005515.PLoS Genet2015-09-29T00:00:002015Correction: Acceleration of the Glycolytic Flux by Steroid Receptor Coactivator-2 Is Essential for Endometrial Decidualization.26456788Bhowmik SK, Putluri V, Kommagani R, Konde SA, Lydon JP, Sreekumar A, Putluri NJournal of mass spectrometry : JMSApplication of (13) C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation. J Mass Spectrom. 2015 Oct; 50(10):1180.J Mass Spectrom2015-10-01T00:00:002015Application of (13) C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation.74Professor54Instructor14Associate Professor2Adjunct Assistant Professor6Adjunct Professor47Distinguished Service Professor27194471Kaushik AK, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, Zaslavsky A, Putluri V, Vasu VT, Zhang Y, Khan AS, Lloyd S, Szafran AT, Dasgupta S, Bader DA, Stossi F, Li H, Samanta S, Cao X, Tsouko E, Huang S, Frigo DE, Chan L, Edwards DP, Kaipparettu BA, Mitsiades N, Weigel NL, Mancini M, McGuire SE, Mehra R, Ittmann MM, Chinnaiyan AM, Putluri N, Palapattu GS, Michailidis G, Sreekumar ANature communicationsInhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer. Nat Commun. 2016 05 19; 7:11612.Nat Commun2016-05-19T00:00:002016Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer.Authorship 32047624Authorship 32063516Authorship 32264720Authorship 3234643326719530Prueitt RL, Wallace TA, Glynn SA, Yi M, Tang W, Luo J, Dorsey TH, Stagliano KE, Gillespie JW, Hudson RS, Terunuma A, Shoe JL, Haines DC, Yfantis HG, Han M, Martin DN, Jordan SV, Borin JF, Naslund MJ, Alexander RB, Stephens RM, Loffredo CA, Lee DH, Putluri N, Sreekumar A, Hurwitz AA, Ambs SCancer researchAn Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers. Cancer Res. 2016 Mar 01; 76(5):1055-1065.Cancer Res2015-12-30T00:00:002015An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers.26802582von Rundstedt FC, Rajapakshe K, Ma J, Arnold JM, Gohlke J, Putluri V, Krishnapuram R, Piyarathna DB, Lotan Y, G?dde D, Roth S, St?rkel S, Levitt JM, Michailidis G, Sreekumar A, Lerner SP, Coarfa C, Putluri NThe Journal of urologyIntegrative Pathway Analysis of Metabolic Signature in Bladder Cancer: A Linkage to The Cancer Genome Atlas Project and Prediction of Survival. J Urol. 2016 06; 195(6):1911-9.J Urol2016-01-21T00:00:002016Integrative Pathway Analysis of Metabolic Signature in Bladder Cancer: A Linkage to The Cancer Genome Atlas Project and Prediction of Survival.26923594Park JH, Vithayathil S, Kumar S, Sung PL, Dobrolecki LE, Putluri V, Bhat VB, Bhowmik SK, Gupta V, Arora K, Wu D, Tsouko E, Zhang Y, Maity S, Donti TR, Graham BH, Frigo DE, Coarfa C, Yotnda P, Putluri N, Sreekumar A, Lewis MT, Creighton CJ, Wong LC, Kaipparettu BACell reportsFatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer. Cell Rep. 2016 Mar 08; 14(9):2154-2165.Cell Rep2016-02-25T00:00:002016Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer.21990318Putluri N, Shojaie A, Vasu VT, Vareed SK, Nalluri S, Putluri V, Thangjam GS, Panzitt K, Tallman CT, Butler C, Sana TR, Fischer SM, Sica G, Brat DJ, Shi H, Palapattu GS, Lotan Y, Weizer AZ, Terris MK, Shariat SF, Michailidis G, Sreekumar ACancer researchMetabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression. Cancer Res. 2011 Dec 15; 71(24):7376-86.Cancer Res2011-10-11T00:00:002011Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression.22480907Scherp P, Putluri N, LeBlanc GJ, Wang ZQ, Zhang XH, Yu Y, Ribnicky D, Cefalu WT, Kheterpal IJournal of proteomicsProteomic analysis reveals cellular pathways regulating carbohydrate metabolism that are modulated in primary human skeletal muscle culture due to treatment with bioactives from Artemisia dracunculus L. J Proteomics. 2012 Jun 18; 75(11):3199-210.J Proteomics2012-03-26T00:00:002012Proteomic analysis reveals cellular pathways regulating carbohydrate metabolism that are modulated in primary human skeletal muscle culture due to treatment with bioactives from Artemisia dracunculus L.Authorship 651463627889186Kettner NM, Voicu H, Finegold MJ, Coarfa C, Sreekumar A, Putluri N, Katchy CA, Lee C, Moore DD, Fu LCancer cellCircadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis. 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Hum Mol Genet. 2017 04 01; 26(7):1305-1317.Hum Mol Genet2017-04-01T00:00:002017Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease.21448452Vareed SK, Bhat VB, Thompson C, Vasu VT, Fermin D, Choi H, Creighton CJ, Gayatri S, Lan L, Putluri N, Thangjam GS, Kaur P, Shabahang M, Giri JG, Nesvizhskii AI, Asea AA, Cashikar AG, Rao A, McLoughlin J, Sreekumar APloS oneMetabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma. PLoS One. 2011 Mar 23; 6(3):e17177.PLoS One2011-03-23T00:00:002011Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma.21789170Putluri N, Shojaie A, Vasu VT, Nalluri S, Vareed SK, Putluri V, Vivekanandan-Giri A, Byun J, Pennathur S, Sana TR, Fischer SM, Palapattu GS, Creighton CJ, Michailidis G, Sreekumar APloS oneMetabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells. PLoS One. 2011; 6(7):e21417.PLoS One2011-07-18T00:00:002011Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells.Authorship 756486827578002Zhang L, Wang J, Wang Y, Zhang Y, Castro P, Shao L, Sreekumar A, Putluri N, Guha N, Deepak S, Padmanaban A, Creighton CJ, Ittmann MCancer researchMNX1 Is Oncogenically Upregulated in African-American Prostate Cancer. 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Nature. 2017 04 13; 544(7649):250-254.Nature2017-04-03T00:00:002017Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming.Authorship 86909310Authorship 873102628640802Wangler MF, Chao YH, Bayat V, Giagtzoglou N, Shinde AB, Putluri N, Coarfa C, Donti T, Graham BH, Faust JE, McNew JA, Moser A, Sardiello M, Baes M, Bellen HJPLoS geneticsPeroxisomal biogenesis is genetically and biochemically linked to carbohydrate metabolism in Drosophila and mouse. PLoS Genet. 2017 Jun; 13(6):e1006825.PLoS Genet2017-06-22T00:00:002017Peroxisomal biogenesis is genetically and biochemically linked to carbohydrate metabolism in Drosophila and mouse.28753886Piyarathna DWB, Rajendiran TM, Putluri V, Vantaku V, Soni T, von Rundstedt FC, Donepudi SR, Jin F, Maity S, Ambati CR, Dong J, G?dde D, Roth S, St?rkel S, Degener S, Michailidis G, Lerner SP, Pennathur S, Lotan Y, Coarfa C, Sreekumar A, Putluri NEuropean urology focusDistinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder. Eur Urol Focus. 2018 12; 4(6):907-915.Eur Urol Focus2017-04-20T00:00:002017Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder.Authorship 8764282028851690Jin F, Thaiparambil J, Donepudi SR, Vantaku V, Piyarathna DWB, Maity S, Krishnapuram R, Putluri V, Gu F, Purwaha P, Bhowmik SK, Ambati CR, von Rundstedt FC, Roghmann F, Berg S, Noldus J, Rajapakshe K, G?dde D, Roth S, St?rkel S, Degener S, Michailidis G, Kaipparettu BA, Karanam B, Terris MK, Kavuri SM, Lerner SP, Kheradmand F, Coarfa C, Sreekumar A, Lotan Y, El-Zein R, Putluri NCancer prevention research (Philadelphia, Pa.)Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer. Cancer Prev Res (Phila). 2017 Oct; 10(10):588-597.Cancer Prev Res (Phila)2017-08-29T00:00:002017Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer.28965825Liu L, MacKenzie KR, Putluri N, Maletic-Savatic M, Bellen HJCell metabolismThe Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D. 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Nature. 2018 04; 556(7700):249-254.Nature2018-04-03T00:00:002018Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.29291380Mindikoglu AL, Opekun AR, Putluri N, Devaraj S, Sheikh-Hamad D, Vierling JM, Goss JA, Rana A, Sood GK, Jalal PK, Inker LA, Mohney RP, Tighiouart H, Christenson RH, Dowling TC, Weir MR, Seliger SL, Hutson WR, Howell CD, Raufman JP, Magder LS, Coarfa CTranslational research : the journal of laboratory and clinical medicineUnique metabolomic signature associated with hepatorenal dysfunction and mortality in cirrhosis. Transl Res. 2018 05; 195:25-47.Transl Res2017-12-12T00:00:002017Unique metabolomic signature associated with hepatorenal dysfunction and mortality in cirrhosis.28924233York B, Li F, Lin F, Marcelo KL, Mao J, Dean A, Gonzales N, Gooden D, Maity S, Coarfa C, Putluri N, Means ARScientific reportsPharmacological inhibition of CaMKK2 with the selective antagonist STO-609 regresses NAFLD. 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Front Immunol. 2018; 9:202.Front Immunol2018-02-16T00:00:002018Pentose Phosphate Shunt Modulates Reactive Oxygen Species and Nitric Oxide Production Controlling Trypanosoma cruzi in Macrophages.29523854Yu W, Chen Y, Dubrulle J, Stossi F, Putluri V, Sreekumar A, Putluri N, Baluya D, Lai SY, Sandulache VCScientific reportsCisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism. Sci Rep. 2018 03 09; 8(1):4306.Sci Rep2018-03-09T00:00:002018Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism.29221154Vantaku V, Donepudi SR, Ambati CR, Jin F, Putluri V, Nguyen K, Rajapakshe K, Coarfa C, Battula VL, Lotan Y, Putluri NOncotargetExpression of ganglioside GD2, reprogram the lipid metabolism and EMT phenotype in bladder cancer. 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Science. 2018 04 27; 360(6387):449-453.Science2018-03-29T00:00:002018Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity.true1ProfessorProfessortrue1ProfessorProfessorD055442Phenomena2003410.786116Metabolometrue1Adjunct ProfessorAdjunct ProfessorD055432Physiology2484790.746687MetabolomicsD005227Chemicals & Drugs2674720.774394Fatty AcidsD005232Chemicals & Drugs42520.975415Fatty Acids, VolatileD001749Disorders29223070.398908Urinary Bladder NeoplasmsAuthorship 91687812Authorship 9182568Authorship 9242755Authorship 9282478Authorship 92932610Authorship 93077011Authorship 9308749Authorship 93103714Authorship 93514812Authorship 93824916Authorship 9387394Authorship 940210228955502Kim H, Li F, He Q, Deng T, Xu J, Jin F, Coarfa C, Putluri N, Liu D, Songyang ZCell discoverySystematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells. 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Ann Neurol. 2018 07; 84(1):23-36.Ann Neurol2018-07-18T00:00:002018Age-related changes in the gut microbiota influence systemic inflammation and stroke outcome.30011843Purwaha P, Gu F, Piyarathna DWB, Rajendiran T, Ravindran A, Omilian AR, Jiralerspong S, Das G, Morrison C, Ambrosone C, Coarfa C, Putluri N, Sreekumar AMetabolitesUnbiased Lipidomic Profiling of Triple-Negative Breast Cancer Tissues Reveals the Association of Sphingomyelin Levels with Patient Disease-Free Survival. Metabolites. 2018 Jul 13; 8(3).Metabolites2018-07-13T00:00:002018Unbiased Lipidomic Profiling of Triple-Negative Breast Cancer Tissues Reveals the Association of Sphingomyelin Levels with Patient Disease-Free Survival.29967256Xing Z, Zhang Y, Liang K, Yan L, Xiang Y, Li C, Hu Q, Jin F, Putluri V, Putluri N, Coarfa C, Sreekumar A, Park PK, Nguyen TK, Wang S, Zhou J, Zhou Y, Marks JR, Hawke DH, Hung MC, Yang L, Han L, Ying H, Lin CCancer researchExpression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer. Cancer Res. 2018 08 15; 78(16):4524-4532.Cancer Res2018-07-02T00:00:002018Expression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer.30170631Ballester LY, Lu G, Zorofchian S, Vantaku V, Putluri V, Yan Y, Arevalo O, Zhu P, Riascos RF, Sreekumar A, Esquenazi Y, Putluri N, Zhu JJActa neuropathologica communicationsAnalysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors. Acta Neuropathol Commun. 2018 08 31; 6(1):85.Acta Neuropathol Commun2018-08-31T00:00:002018Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors.30177747Szwarc MM, Kommagani R, Putluri V, Dubrulle J, Stossi F, Mancini MA, Coarfa C, Lanz RB, Putluri N, DeMayo FJ, Lydon JP, O'Malley BWScientific reportsSteroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells. Sci Rep. 2018 09 03; 8(1):13134.Sci Rep2018-09-03T00:00:002018Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells.30360420Khan V, Putluri N, Sreekumar A, Mindikoglu ALMetabolitesCurrent Applications of Metabolomics in Cirrhosis. Metabolites. 2018 Oct 22; 8(4).Metabolites2018-10-22T00:00:002018Current Applications of Metabolomics in Cirrhosis.30602056Vantaku V, Donepudi SR, Piyarathna DWB, Amara CS, Ambati CR, Tang W, Putluri V, Chandrashekar DS, Varambally S, Terris MK, Davies K, Ambs S, Bollag R, Apolo AB, Sreekumar A, Putluri NCancerLarge-scale profiling of serum metabolites in African American and European American patients with bladder cancer reveals metabolic pathways associated with patient survival. Cancer. 2019 03 15; 125(6):921-932.Cancer2019-01-02T00:00:002019Large-scale profiling of serum metabolites in African American and European American patients with bladder cancer reveals metabolic pathways associated with patient survival.30741721Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, Nguyen TK, Park PK, Egranov SD, Ambati CR, Putluri N, Hawke DH, Han L, Hung MC, Danesh FR, Yang L, Lin CThe Journal of clinical investigationPTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019 03 01; 129(3):1129-1151.J Clin Invest2019-02-11T00:00:002019PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease.30723176Jiao L, Maity S, Coarfa C, Rajapakshe K, Chen L, Jin F, Putluri V, Tinker LF, Mo Q, Chen F, Sen S, Sangi-Hyghpeykar H, El-Serag HB, Putluri NCancer prevention research (Philadelphia, Pa.)A Prospective Targeted Serum Metabolomics Study of Pancreatic Cancer in Postmenopausal Women. Cancer Prev Res (Phila). 2019 04; 12(4):237-246.Cancer Prev Res (Phila)2019-02-05T00:00:002019A Prospective Targeted Serum Metabolomics Study of Pancreatic Cancer in Postmenopausal Women.30687688Moye LM, Liu Y, Coarfa C, Putluri N, Rhoads JMFrontiers in pediatricsPlasma Urea Cycle Metabolites May Be Useful Biomarkers in Children With Eosinophilic Esophagitis. Front Pediatr. 2018; 6:423.Front Pediatr2019-01-10T00:00:002019Plasma Urea Cycle Metabolites May Be Useful Biomarkers in Children With Eosinophilic Esophagitis.2022-05-31NIHPUTLURI, NAGIREDDY2017-06-05Racial Disparity in Bladder Cancer and Identification of Altered Metabolism in African American Compare to European Bladder CancerR01CA2202972024-03-31NIHEL-ZEIN, RANDA A;PUTLURI, NAGIREDDY2018-04-01Identify the DNA Adduct and Associated Metabolic Alterations in Bladder Cancer of SmokersR01CA216426Principal InvestigatorPrincipal InvestigatorUrologyDepartment of MedicineDepartment of Molecular & Cellular BiologyDepartment of Molecular & Human GeneticsDepartment of UrologyUrologyMedicine-Athero & LipoproteinsMolecular & Cellular BiologyMolecular & Human GeneticsBaylor College of MedicineCRISTIANCOARFACRISTIAN COARFA0.000000000000000.000000000000001149COARFA, CRISTIANAssociate ProfessorLIXINLI XIN39.09225730000000-77.209617300000001405XIN, LIAdjunct ProfessorARUNSREEKUMARARUN SREEKUMAR39.09225730000000-77.209617300000001838SREEKUMAR, ARUNProfessorERICBOERWINKLEERIC BOERWINKLE0.000000000000000.000000000000002653BOERWINKLE, ERICAdjunct ProfessorPINGYIPING YI39.09225730000000-77.20961730000000498YI, PINGAdjunct Assistant ProfessorSETHLERNERSETH LERNER29.70990600000000-95.402830000000002886LERNER, SETHProfessorFABIOSTOSSIFABIO STOSSI39.09225730000000-77.209617300000003974STOSSI, FABIOAssociate ProfessorROBBMOSESROBB MOSES39.09225730000000-77.209617300000003969MOSES, ROBBProfessorDEANEDWARDSDEAN EDWARDS39.09225730000000-77.20961730000000920EDWARDS, DEANProfessorBENNYKAIPPARETTUBENNY KAIPPARETTU29.71073630000000-95.39660450000000970KAIPPARETTU, BENNYAssociate Professor3.274940.0119547636research areas6.65630.0303989199coauthor of134.57916.685160similar to11144selected publicationsAuthorship 94136125Authorship 9416064Authorship 9425502630846479Vantaku V, Dong J, Ambati CR, Perera D, Donepudi SR, Amara CS, Putluri V, Ravi SS, Robertson MJ, Piyarathna DWB, Villanueva M, von Rundstedt FC, Karanam B, Ballester LY, Terris MK, Bollag RJ, Lerner SP, Apolo AB, Villanueva H, Lee M, Sikora AG, Lotan Y, Sreekumar A, Coarfa C, Putluri NClinical cancer research : an official journal of the American Association for Cancer ResearchMulti-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer. Clin Cancer Res. 2019 06 15; 25(12):3689-3701.Clin Cancer Res2019-03-07T00:00:002019Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer.BERTO'MALLEYBERT O'MALLEY0.000000000000000.000000000000002464O'MALLEY, BERTDistinguished Service Professor30773067Amara CS, Vantaku V, Lotan Y, Putluri NExpert review of proteomicsRecent advances in the metabolomic study of bladder cancer. Expert Rev Proteomics. 2019 04; 16(4):315-324.Expert Rev Proteomics2019-02-26T00:00:002019Recent advances in the metabolomic study of bladder cancer.30787016Fischer GM, Jalali A, Kircher DA, Lee WC, McQuade JL, Haydu LE, Joon AY, Reuben A, de Macedo MP, Carapeto FCL, Yang C, Srivastava A, Ambati CR, Sreekumar A, Hudgens CW, Knighton B, Deng W, Ferguson SD, Tawbi HA, Glitza IC, Gershenwald JE, Vashisht Gopal YN, Hwu P, Huse JT, Wargo JA, Futreal PA, Putluri N, Lazar AJ, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL, Tetzlaff MT, Davies MACancer discoveryMolecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. Cancer Discov. 2019 05; 9(5):628-645.Cancer Discov2019-02-20T00:00:002019Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases.Authorship 9429558Authorship 9430441630642841Amara CS, Ambati CR, Vantaku V, Badrajee Piyarathna DW, Donepudi SR, Ravi SS, Arnold JM, Putluri V, Chatta G, Guru KA, Badr H, Terris MK, Bollag RJ, Sreekumar A, Apolo AB, Putluri NCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive OncologySerum Metabolic Profiling Identified a Distinct Metabolic Signature in Bladder Cancer Smokers: A Key Metabolic Enzyme Associated with Patient Survival. Cancer Epidemiol Biomarkers Prev. 2019 04; 28(4):770-781.Cancer Epidemiol Biomarkers Prev2019-01-14T00:00:002019Serum Metabolic Profiling Identified a Distinct Metabolic Signature in Bladder Cancer Smokers: A Key Metabolic Enzyme Associated with Patient Survival.30920960Piyarathna DWB, Balasubramanian A, Arnold JM, Lloyd SM, Karanam B, Castro P, Ittmann MM, Putluri N, Navone N, Jones JA, Yu W, Sandulache VC, Sikora AG, Michailidis G, Sreekumar AThe Journal of clinical investigationERR1 and PGC1a associated mitochondrial alterations correlate with pan-cancer disparity in African Americans. J Clin Invest. 2019 03 28; 129(6):2351-2356.J Clin Invest2019-03-28T00:00:002019ERR1 and PGC1a associated mitochondrial alterations correlate with pan-cancer disparity in African Americans.Authorship 9482722131160797Hu Q, Ye Y, Chan LC, Li Y, Liang K, Lin A, Egranov SD, Zhang Y, Xia W, Gong J, Pan Y, Chatterjee SS, Yao J, Evans KW, Nguyen TK, Park PK, Liu J, Coarfa C, Donepudi SR, Putluri V, Putluri N, Sreekumar A, Ambati CR, Hawke DH, Marks JR, Gunaratne PH, Caudle AS, Sahin AA, Hortobagyi GN, Meric-Bernstam F, Chen L, Yu D, Hung MC, Curran MA, Han L, Lin C, Yang LNature immunologyOncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression. Nat Immunol. 2019 07; 20(7):835-851.Nat Immunol2019-06-03T00:00:002019Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.Authorship 9491072031198906Bader DA, Hartig SM, Putluri V, Foley C, Hamilton MP, Smith EA, Saha PK, Panigrahi A, Walker C, Zong L, Martini-Stoica H, Chen R, Rajapakshe K, Coarfa C, Sreekumar A, Mitsiades N, Bankson JA, Ittmann MM, O'Malley BW, Putluri N, McGuire SENature metabolismMitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer. Nat Metab. 2019 01; 1(1):70-85.Nat Metab2018-11-19T00:00:002018Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer.Authorship 950077931208719Suter MA, Aagaard KM, Coarfa C, Robertson M, Zhou G, Jackson BP, Thompson D, Putluri V, Putluri N, Hagan J, Wang L, Jiang W, Lingappan K, Moorthy BBiochemical and biophysical research communicationsAssociation between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts from Superfund sites in Harris County, and increased risk of preterm birth (PTB). Biochem Biophys Res Commun. 2019 08 20; 516(2):344-349.Biochem Biophys Res Commun2019-06-14T00:00:002019Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts from Superfund sites in Harris County, and increased risk of preterm birth (PTB).Authorship 9517225Authorship 95179510Authorship 9518582131284295Vantaku V, Amara CS, Piyarathna DWB, Donepudi SR, Ambati CR, Putluri V, Tang W, Rajapakshe K, Estecio MR, Terris MK, Castro PD, Ittmann MM, Williams SB, Lerner SP, Sreekumar A, Bollag R, Coarfa C, Kornberg MD, Lotan Y, Ambs S, Putluri NCarcinogenesisDNA methylation patterns in bladder tumors of African American patients point to distinct alterations in xenobiotic metabolism. Carcinogenesis. 2019 11 25; 40(11):1332-1340.Carcinogenesis2019-11-25T00:00:002019DNA methylation patterns in bladder tumors of African American patients point to distinct alterations in xenobiotic metabolism.31279675Colleluori G, Aguirre L, Phadnis U, Fowler K, Armamento-Villareal R, Sun Z, Brunetti L, Hyoung Park J, Kaipparettu BA, Putluri N, Auetumrongsawat V, Yarasheski K, Qualls C, Villareal DTCell metabolismAerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss. Cell Metab. 2019 08 06; 30(2):261-273.e6.Cell Metab2019-07-03T00:00:002019Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss.31296531Tang W, Putluri V, Ambati CR, Dorsey TH, Putluri N, Ambs SClinical cancer research : an official journal of the American Association for Cancer ResearchLiver- and Microbiome-derived Bile Acids Accumulate in Human Breast Tumors and Inhibit Growth and Improve Patient Survival. Clin Cancer Res. 2019 10 01; 25(19):5972-5983.Clin Cancer Res2019-07-11T00:00:002019Liver- and Microbiome-derived Bile Acids Accumulate in Human Breast Tumors and Inhibit Growth and Improve Patient Survival.Authorship 9520411731308490Arnold JM, Gu F, Ambati CR, Rasaily U, Ramirez-Pena E, Joseph R, Manikkam M, San Martin R, Charles C, Pan Y, Chatterjee SS, Den Hollander P, Zhang W, Nagi C, Sikora AG, Rowley D, Putluri N, Zhang XH, Karanam B, Mani SA, Sreekumar AOncogeneUDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression. Oncogene. 2020 04; 39(15):3089-3101.Oncogene2019-07-15T00:00:002019UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression.Authorship 9529672131355949Choi S, Dong B, Lin CJ, Heo MJ, Kim KH, Sun Z, Wagner M, Putluri N, Suh JM, Wang MC, Moore DDHepatology (Baltimore, Md.)Methyl-Sensing Nuclear Receptor Liver Receptor Homolog-1 Regulates Mitochondrial Function in Mouse Hepatocytes. Hepatology. 2020 03; 71(3):1055-1069.Hepatology2019-12-23T00:00:002019Methyl-Sensing Nuclear Receptor Liver Receptor Homolog-1 Regulates Mitochondrial Function in Mouse Hepatocytes.31360899Gohlke JH, Lloyd SM, Basu S, Putluri V, Vareed SK, Rasaily U, Piyarathna DWB, Fuentes H, Rajendiran TM, Dorsey TH, Ambati CR, Sonavane R, Karanam B, Bhowmik SK, Kittles R, Ambs S, Mims MP, Ittmann M, Jones JA, Palapattu G, Putluri N, Michailidis G, Sreekumar AJNCI cancer spectrumMethionine-Homocysteine Pathway in African-American Prostate Cancer. JNCI Cancer Spectr. 2019 Jun; 3(2):pkz019.JNCI Cancer Spectr2019-04-25T00:00:002019Methionine-Homocysteine Pathway in African-American Prostate Cancer.Authorship 9533112331383940Vantaku V, Putluri V, Bader DA, Maity S, Ma J, Arnold JM, Rajapakshe K, Donepudi SR, von Rundstedt FC, Devarakonda V, Dubrulle J, Karanam B, McGuire SE, Stossi F, Jain AK, Coarfa C, Cao Q, Sikora AG, Villanueva H, Kavuri SM, Lotan Y, Sreekumar A, Putluri NOncogeneEpigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. Oncogene. 2020 10; 39(40):6265-6285.Oncogene2019-08-05T00:00:002019Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression.Authorship 95480320Authorship 9549071131483291Madison MC, Landers CT, Gu BH, Chang CY, Tung HY, You R, Hong MJ, Baghaei N, Song LZ, Porter P, Putluri N, Salas R, Gilbert BE, Levental I, Campen MJ, Corry DB, Kheradmand FThe Journal of clinical investigationElectronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine. J Clin Invest. 2019 10 01; 129(10):4290-4304.J Clin Invest2019-10-01T00:00:002019Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine.31474581Piyarathna DWB, Rajendiran TM, Putluri V, Vantaku V, Soni T, von Rundstedt FC, Donepudi SR, Jin F, Maity S, Ambati CR, Dong J, G?dde D, Roth S, St?rkel S, Degener S, Michailidis G, Lerner SP, Pennathur S, Lotan Y, Coarfa C, Sreekumar A, Putluri NEuropean urology focusErratum to "Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder" [Eur Urol Focus 2018;4:907-915]. Eur Urol Focus. 2019 Sep; 5(5):920.Eur Urol Focus2019-08-30T00:00:002019Erratum to "Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder" [Eur Urol Focus 2018;4:907-915].true1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professortrue1Distinguished Service ProfessorDistinguished Service ProfessorKARTHIK REDDYKAMI REDDYKARTHIK REDDY KAMI REDDY15065KAMI REDDY, KARTHIK REDDYInstructorAuthorship 96156210Authorship 961834631780580Xiong J, He J, Xie WP, Hinojosa E, Ambati CSR, Putluri N, Kim HE, Zhu MX, Du GJournal of cell scienceRapid affinity purification of intracellular organelles using a twin strep tag. J Cell Sci. 2019 12 13; 132(24).J Cell Sci2019-12-13T00:00:002019Rapid affinity purification of intracellular organelles using a twin strep tag.31762797Ambati CR, Vantaku V, Donepudi SR, Amara CS, Ravi SS, Mandalapu A, Perla M, Putluri V, Sreekumar A, Putluri NAnalytical methods : advancing methods and applicationsMeasurement of methylated metabolites using Liquid Chromatography-Mass Spectrometry and its biological application. Anal Methods. 2019 Jan 07; 11(1):49-57.Anal Methods2018-11-15T00:00:002018Measurement of methylated metabolites using Liquid Chromatography-Mass Spectrometry and its biological application.Authorship 9624681131827727Vantaku V, Donepudi SR, Ambati CR, Jin F, Putluri V, Nguyen K, Rajapakshe K, Coarfa C, Battula VL, Lotan Y, Putluri NOncotargetCorrection: Expression of ganglioside GD2, reprogram the lipid metabolism and EMT phenotype in bladder cancer. Oncotarget. 2019 Nov 26; 10(63):6843-6844.Oncotarget2019-11-26T00:00:002019Correction: Expression of ganglioside GD2, reprogram the lipid metabolism and EMT phenotype in bladder cancer.Authorship 9748158Authorship 975495931924743Wooton-Kee CR, Robertson M, Zhou Y, Dong B, Sun Z, Kim KH, Liu H, Xu Y, Putluri N, Saha P, Coarfa C, Moore DD, Nuotio-Antar AMProceedings of the National Academy of Sciences of the United States of AmericaMetabolic dysregulation in the Atp7b-/- Wilson's disease mouse model. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):2076-2083.Proc Natl Acad Sci U S A2020-01-10T00:00:002020Metabolic dysregulation in the Atp7b-/- Wilson's disease mouse model.Authorship 975731531932841Zhang X, Wang X, Wang XQD, Su J, Putluri N, Zhou T, Qu Y, Jeong M, Guzman A, Rosas C, Huang Y, Sreekumar A, Li W, Goodell MABloodDnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis. Blood. 2020 03 12; 135(11):845-856.Blood2020-03-12T00:00:002020Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis.Authorship 977465732025330Mindikoglu AL, Coarfa C, Opekun AR, Shah VH, Arab JP, Lazaridis KN, Putluri N, Ambati CR, Robertson MJ, Devaraj S, Jalal PK, Rana A, Goss JA, Dowling TC, Weir MR, Seliger SL, Raufman JP, Bernard DW, Vierling JMFuture science OAMetabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis. Future Sci OA. 2019 Dec 17; 6(2):FSO441.Future Sci OA2019-12-17T00:00:002019Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis.Authorship 9778322432046984Dey P, Li J, Zhang J, Chaurasiya S, Strom A, Wang H, Liao WT, Cavallaro F, Denz P, Bernard V, Yen EY, Genovese G, Gulhati P, Liu J, Chakravarti D, Deng P, Zhang T, Carbone F, Chang Q, Ying H, Shang X, Spring DJ, Ghosh B, Putluri N, Maitra A, Wang YA, DePinho RACancer discoveryOncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment. Cancer Discov. 2020 04; 10(4):608-625.Cancer Discov2020-02-11T00:00:002020Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment.Authorship 979839532138161Honarpisheh P, Reynolds CR, Blasco Conesa MP, Moruno Manchon JF, Putluri N, Bhattacharjee MB, Urayama A, McCullough LD, Ganesh BPInternational journal of molecular sciencesDysregulated Gut Homeostasis Observed Prior to the Accumulation of the Brain Amyloid-? in Tg2576 Mice. Int J Mol Sci. 2020 Mar 03; 21(5).Int J Mol Sci2020-03-03T00:00:002020Dysregulated Gut Homeostasis Observed Prior to the Accumulation of the Brain Amyloid-? in Tg2576 Mice.Authorship 9800911732214199Arnold JM, Gu F, Ambati CR, Rasaily U, Ramirez-Pena E, Joseph R, Manikkam M, Martin RS, Charles C, Pan Y, Chatterjee SS, Den Hollander P, Zhang W, Nagi C, Sikora AG, Rowley D, Putluri N, Zhang XH, Karanam B, Mani SA, Sreekumar AOncogeneCorrection: UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression. Oncogene. 2020 Apr; 39(15):3226-3228.Oncogene2020-04-01T00:00:002020Correction: UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression.true1Adjunct ProfessorAdjunct ProfessorAuthorship 9863821432243837Alam H, Tang M, Maitituoheti M, Dhar SS, Kumar M, Han CY, Ambati CR, Amin SB, Gu B, Chen TY, Lin YH, Chen J, Muller FL, Putluri N, Flores ER, DeMayo FJ, Baseler L, Rai K, Lee MGCancer cellKMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer. Cancer Cell. 2020 04 13; 37(4):599-617.e7.Cancer Cell2020-04-02T00:00:002020KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer.Authorship 9884121032354259Lee J, d'Aigle J, Atadja L, Quaicoe V, Honarpisheh P, Ganesh BP, Hassan A, Graf J, Petrosino J, Putluri N, Zhu L, Durgan DJ, Bryan RM, McCullough LD, Venna VRCirculation researchGut Microbiota-Derived Short-Chain Fatty Acids Promote Poststroke Recovery in Aged Mice. Circ Res. 2020 07 31; 127(4):453-465.Circ Res2020-05-01T00:00:002020Gut Microbiota-Derived Short-Chain Fatty Acids Promote Poststroke Recovery in Aged Mice.Authorship 9889361632385268Trevi?o LS, Dong J, Kaushal A, Katz TA, Jangid RK, Robertson MJ, Grimm SL, Ambati CSR, Putluri V, Cox AR, Kim KH, May TD, Gallo MR, Moore DD, Hartig SM, Foulds CE, Putluri N, Coarfa C, Walker CLNature communicationsEpigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood. Nat Commun. 2020 05 08; 11(1):2316.Nat Commun2020-05-08T00:00:002020Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood.Authorship 9897291432426999Yang T, Chakraborty S, Saha P, Mell B, Cheng X, Yeo JY, Mei X, Zhou G, Mandal J, Golonka R, Yeoh BS, Putluri V, Piyarathna DWB, Putluri N, McCarthy CG, Wenceslau CF, Sreekumar A, Gewirtz AT, Vijay-Kumar M, Joe BHypertension (Dallas, Tex. : 1979)Gnotobiotic Rats Reveal That Gut Microbiota Regulates Colonic mRNA of Ace2, the Receptor for SARS-CoV-2 Infectivity. Hypertension. 2020 07; 76(1):e1-e3.Hypertension2020-05-19T00:00:002020Gnotobiotic Rats Reveal That Gut Microbiota Regulates Colonic mRNA of Ace2, the Receptor for SARS-CoV-2 Infectivity.Authorship 9914501432518142Lovisa S, Fletcher-Sananikone E, Sugimoto H, Hensel J, Lahiri S, Hertig A, Taduri G, Lawson E, Dewar R, Revuelta I, Kato N, Wu CJ, Bassett RL, Putluri N, Zeisberg M, Zeisberg EM, LeBleu VS, Kalluri RScience signalingEndothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis. Sci Signal. 2020 06 09; 13(635).Sci Signal2020-06-09T00:00:002020Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis.Authorship 9929213Authorship 992989132599707Yu W, Chen Y, Putluri N, Coarfa C, Robertson MJ, Putluri V, Stossi F, Dubrulle J, Mancini MA, Pang JC, Nguyen T, Baluya D, Myers JN, Lai SY, Sandulache VCCancersAcquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress. Cancers (Basel). 2020 Jun 24; 12(6).Cancers (Basel)2020-06-24T00:00:002020Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress.32602743Dono A, Patrizz A, McCormack RM, Putluri N, Ganesh BP, Kaur B, McCullough LD, Ballester LY, Esquenazi YCNS oncologyGlioma induced alterations in fecal short-chain fatty acids and neurotransmitters. CNS Oncol. 2020 06; 9(2):CNS57.CNS Oncol2020-06-30T00:00:002020Glioma induced alterations in fecal short-chain fatty acids and neurotransmitters.Authorship 995628632726451Gastelum G, Jiang W, Wang L, Zhou G, Borkar R, Putluri N, Moorthy BToxicological sciences : an official journal of the Society of ToxicologyPolycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2. Toxicol Sci. 2020 10 01; 177(2):347-361.Toxicol Sci2020-10-01T00:00:002020Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2.Authorship 9971959Authorship 9974992332820250Vantaku V, Putluri V, Bader DA, Maity S, Ma J, Arnold JM, Rajapakshe K, Donepudi SR, von Rundstedt FC, Devarakonda V, Dubrulle J, Karanam B, McGuire SE, Stossi F, Jain AK, Coarfa C, Cao Q, Sikora AG, Villanueva H, Kavuri SM, Lotan Y, Sreekumar A, Putluri NOncogeneCorrection: Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. Oncogene. 2020 Oct; 39(40):6387-6392.Oncogene2020-10-01T00:00:002020Correction: Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression.32799658Saha PK, Hamilton MP, Rajapakshe K, Putluri V, Felix JB, Masschelin P, Cox AR, Bajaj M, Putluri N, Coarfa C, Hartig SMAmerican journal of physiology. Endocrinology and metabolismmiR-30a targets gene networks that promote browning of human and mouse adipocytes. Am J Physiol Endocrinol Metab. 2020 10 01; 319(4):E667-E677.Am J Physiol Endocrinol Metab2020-08-17T00:00:002020miR-30a targets gene networks that promote browning of human and mouse adipocytes.Authorship 9985066Authorship 998536732868820Takayasu T, Shah M, Dono A, Yan Y, Borkar R, Putluri N, Zhu JJ, Hama S, Yamasaki F, Tahara H, Sugiyama K, Kurisu K, Esquenazi Y, Ballester LYScientific reportsCerebrospinal fluid ctDNA and metabolites are informative biomarkers for the evaluation of CNS germ cell tumors. Sci Rep. 2020 08 31; 10(1):14326.Sci Rep2020-08-31T00:00:002020Cerebrospinal fluid ctDNA and metabolites are informative biomarkers for the evaluation of CNS germ cell tumors.32872332Mohammed A, F K Alghetaa H, Miranda K, Wilson K, P Singh N, Cai G, Putluri N, Nagarkatti P, Nagarkatti MInternational journal of molecular sciences?9-Tetrahydrocannabinol Prevents Mortality from Acute Respiratory Distress Syndrome through the Induction of Apoptosis in Immune Cells, Leading to Cytokine Storm Suppression. Int J Mol Sci. 2020 Aug 28; 21(17).Int J Mol Sci2020-08-28T00:00:002020?9-Tetrahydrocannabinol Prevents Mortality from Acute Respiratory Distress Syndrome through the Induction of Apoptosis in Immune Cells, Leading to Cytokine Storm Suppression.Authorship 999155632897773Lee J, Venna VR, Durgan DJ, Shi H, Hudobenko J, Putluri N, Petrosino J, McCullough LD, Bryan RMGut microbesYoung versus aged microbiota transplants to germ-free mice: increased short-chain fatty acids and improved cognitive performance. Gut Microbes. 2020 11 09; 12(1):1-14.Gut Microbes2020-09-08T00:00:002020Young versus aged microbiota transplants to germ-free mice: increased short-chain fatty acids and improved cognitive performance.Authorship 10010741632994273Cox AR, Chernis N, Bader DA, Saha PK, Masschelin PM, Felix JB, Sharp R, Lian Z, Putluri V, Rajapakshe K, Kim KH, Villareal DT, Armamento-Villareal R, Wu H, Coarfa C, Putluri N, Hartig SMDiabetesSTAT1 Dissociates Adipose Tissue Inflammation From Insulin Sensitivity in Obesity. Diabetes. 2020 12; 69(12):2630-2641.Diabetes2020-09-29T00:00:002020STAT1 Dissociates Adipose Tissue Inflammation From Insulin Sensitivity in Obesity.Authorship 10036721133115805Sawant Dessai A, Dominguez MP, Chen UI, Hasper J, Prechtl C, Yu C, Katsuta E, Dai T, Zhu B, Jung SY, Putluri N, Takabe K, Zhang XH, O'Malley BW, Dasgupta SCancer researchTranscriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone. Cancer Res. 2021 01 01; 81(1):50-63.Cancer Res2020-10-28T00:00:002020Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone.Authorship 10062628Authorship 1006388433269338Williams SB, Shan Y, Jazzar U, Kerr PS, Okereke I, Klimberg VS, Tyler DS, Putluri N, Lopez DS, Prochaska JD, Elferink C, Baillargeon JG, Kuo YF, Mehta HBJNCI cancer spectrumProximity to Oil Refineries and Risk of Cancer: A Population-Based Analysis. JNCI Cancer Spectr. 2020 Dec; 4(6):pkaa088.JNCI Cancer Spectr2020-10-07T00:00:002020Proximity to Oil Refineries and Risk of Cancer: A Population-Based Analysis.33277471Meng H, Gonzales NM, Lonard DM, Putluri N, Zhu B, Dacso CC, York B, O'Malley BWNature communicationsXBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis. Nat Commun. 2020 12 04; 11(1):6215.Nat Commun2020-12-04T00:00:002020XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis.Authorship 1006684433300995Nagandla H, Robertson MJ, Putluri V, Putluri N, Coarfa C, Weigel NLEndocrinologyIsoform-specific Activities of Androgen Receptor and its Splice Variants in Prostate Cancer Cells. Endocrinology. 2021 03 01; 162(3).Endocrinology2021-03-01T00:00:002021Isoform-specific Activities of Androgen Receptor and its Splice Variants in Prostate Cancer Cells.Authorship 1007062933331878Becker W, Alrafas HR, Busbee PB, Walla MD, Wilson K, Miranda K, Cai G, Putluri V, Putluri N, Nagarkatti M, Nagarkatti PSJournal of Crohn's & colitisCannabinoid Receptor Activation on Haematopoietic Cells and Enterocytes Protects against Colitis. J Crohns Colitis. 2021 Jun 22; 15(6):1032-1048.J Crohns Colitis2021-06-22T00:00:002021Cannabinoid Receptor Activation on Haematopoietic Cells and Enterocytes Protects against Colitis.Authorship 10141771333742144Chen Y, Maniakas A, Tan L, Cui M, Le X, Niedzielski JS, Michel KA, Harlan CJ, Lu W, Henderson YC, Mohamed ASR, Lorenzi PL, Putluri N, Bankson JA, Sandulache VC, Lai SYBritish journal of cancerDevelopment of a rational strategy for integration of lactate dehydrogenase A suppression into therapeutic algorithms for head and neck cancer. Br J Cancer. 2021 05; 124(10):1670-1679.Br J Cancer2021-03-19T00:00:002021Development of a rational strategy for integration of lactate dehydrogenase A suppression into therapeutic algorithms for head and neck cancer.Authorship 10192511134025677Amobi-McCloud A, Muthuswamy R, Battaglia S, Yu H, Liu T, Wang J, Putluri V, Singh PK, Qian F, Huang RY, Putluri N, Tsuji T, Lugade AA, Liu S, Odunsi KFrontiers in immunologyIDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation. Front Immunol. 2021; 12:678999.Front Immunol2021-04-16T00:00:002021IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation.Authorship 102351720Authorship 10240991334183658Moreno-Smith M, Milazzo G, Tao L, Fekry B, Zhu B, Mohammad MA, Di Giacomo S, Borkar R, Reddy KRK, Capasso M, Vasudevan SA, Sumazin P, Hicks J, Putluri N, Perini G, Eckel-Mahan K, Burris TP, Barbieri ENature communicationsRestoration of the molecular clock is tumor suppressive in neuroblastoma. Nat Commun. 2021 06 28; 12(1):4006.Nat Commun2021-06-28T00:00:002021Restoration of the molecular clock is tumor suppressive in neuroblastoma.34239044Karunanithi S, Liu R, Hou Y, Gonzalez G, Oldford N, Roe AJ, Idipilly N, Gupta K, Amara CS, Putluri S, Lee GK, Valentin-Goyco J, Stetson L, Moreton SA, Putluri V, Kavuri SM, Saunthararajah Y, de Lima M, Tochtrop GP, Putluri N, Wald DNOncogeneThioredoxin reductase is a major regulator of metabolism in leukemia cells. Oncogene. 2021 08; 40(33):5236-5246.Oncogene2021-07-08T00:00:002021Thioredoxin reductase is a major regulator of metabolism in leukemia cells.Authorship 102682419Authorship 1027192634344789Yang D, Patel S, Szlachcic WJ, Chmielowiec J, Scaduto D, Putluri N, Sreekumar A, Suliburk J, Metzker M, Balasubramanyam A, Borowiak MDiabetesPancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes. Diabetes. 2021 10; 70(10):2419-2429.Diabetes2021-08-03T00:00:002021Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes.34353949Li Y, Tan Z, Zhang Y, Zhang Z, Hu Q, Liang K, Jun Y, Ye Y, Li YC, Li C, Liao L, Xu J, Xing Z, Pan Y, Chatterjee SS, Nguyen TK, Hsiao H, Egranov SD, Putluri N, Coarfa C, Hawke DH, Gunaratne PH, Tsai KL, Han L, Hung MC, Calin GA, Namour F, Gu?ant JL, Muntau AC, Blau N, Sutton VR, Schiff M, Feillet F, Zhang S, Lin C, Yang LScience (New York, N.Y.)A noncoding RNA modulator potentiates phenylalanine metabolism in mice. Science. 2021 08 06; 373(6555):662-673.Science2021-08-06T00:00:002021A noncoding RNA modulator potentiates phenylalanine metabolism in mice.Authorship 10273391534365742Tao L, Moreno-Smith M, Ibarra-Garc?a-Padilla R, Milazzo G, Drolet NA, Hernandez BE, Oh YS, Patel I, Kim JJ, Zorman B, Patel T, Kamal AHM, Zhao Y, Hicks J, Vasudevan SA, Putluri N, Coarfa C, Sumazin P, Perini G, Parchem RJ, Uribe RA, Barbieri EAdvanced science (Weinheim, Baden-Wurttemberg, Germany)CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming. Adv Sci (Weinh). 2021 10; 8(19):e2005047.Adv Sci (Weinh)2021-08-08T00:00:002021CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming.true1Associate ProfessorAssociate ProfessorAuthorship 1030848734593556Chadchan SB, Popli P, Ambati CR, Tycksen E, Han SJ, Bulun SE, Putluri N, Biest SW, Kommagani RLife science allianceGut microbiota-derived short-chain fatty acids protect against the progression of endometriosis. Life Sci Alliance. 2021 12; 4(12).Life Sci Alliance2021-09-30T00:00:002021Gut microbiota-derived short-chain fatty acids protect against the progression of endometriosis.Authorship 1032299534691356Burke R, Chu C, Zhou GD, Putluri V, Putluri N, Stading RE, Couroucli X, Lingappan K, Moorthy BOxidative medicine and cellular longevityRole of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells. Oxid Med Cell Longev. 2021; 2021:5544600.Oxid Med Cell Longev2021-10-15T00:00:002021Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells.Authorship 10332231034811508Jaggupilli A, Ly S, Nguyen K, Anand V, Yuan B, El-Dana F, Yan Y, Arvanitis Z, Piyarathna DWB, Putluri N, Piwnica-Worms H, Manning HC, Andreeff M, Battula VLBritish journal of cancerMetabolic stress induces GD2+ cancer stem cell-like phenotype in triple-negative breast cancer. Br J Cancer. 2022 03; 126(4):615-627.Br J Cancer2021-11-22T00:00:002021Metabolic stress induces GD2+ cancer stem cell-like phenotype in triple-negative breast cancer.Authorship 10376241835034472Song S, Tien CL, Cui H, Basil P, Zhu N, Gong Y, Li W, Li H, Fan Q, Min Choi J, Luo W, Xue Y, Cao R, Zhou W, Ortiz AR, Stork B, Mundra V, Putluri N, York B, Chu M, Chang J, Yun Jung S, Xie L, Song J, Zhang L, Sun ZCirculationMyocardial Rev-erb-Mediated Diurnal Metabolic Rhythm and Obesity Paradox. Circulation. 2022 02 08; 145(6):448-464.Circulation2022-01-17T00:00:002022Myocardial Rev-erb-Mediated Diurnal Metabolic Rhythm and Obesity Paradox.Authorship 10380495Authorship 103840631Authorship 10389018Authorship 10401781135294258Odunsi K, Qian F, Lugade AA, Yu H, Geller MA, Fling SP, Kaiser JC, Lacroix AM, D'Amico L, Ramchurren N, Morishima C, Disis ML, Dennis L, Danaher P, Warren S, Nguyen VA, Ravi S, Tsuji T, Rosario S, Zha W, Hutson A, Liu S, Lele S, Zsiros E, McGray AJR, Chiello J, Koya R, Chodon T, Morrison CD, Putluri V, Putluri N, Mager DE, Gunawan R, Cheever MA, Battaglia S, Matsuzaki JScience translational medicineMetabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses. Sci Transl Med. 2022 03 16; 14(636):eabg8402.Sci Transl Med2022-03-16T00:00:002022Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses.35263593Meng H, Gonzales NM, Jung SY, Lu Y, Putluri N, Zhu B, Dacso CC, Lonard DM, O'Malley BWCell reportsDefining the mammalian coactivation of hepatic 12-h clock and lipid metabolism. Cell Rep. 2022 03 08; 38(10):110491.Cell Rep2022-03-08T00:00:002022Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism.35338351El Saie A, Fu C, Grimm SL, Robertson MJ, Hoffman K, Putluri V, Ambati CSR, Putluri N, Shivanna B, Coarfa C, Pammi MPediatric researchMetabolome and microbiome multi-omics integration from a murine lung inflammation model of bronchopulmonary dysplasia. Pediatr Res. 2022 12; 92(6):1580-1589.Pediatr Res2022-03-25T00:00:002022Metabolome and microbiome multi-omics integration from a murine lung inflammation model of bronchopulmonary dysplasia.35050130Ravindran A, Piyarathna DWB, Gohlke J, Putluri V, Soni T, Lloyd S, Castro P, Pennathur S, Jones JA, Ittmann M, Putluri N, Michailidis G, Rajendiran TM, Sreekumar AMetabolitesLipid Alterations in African American Men with Prostate Cancer. Metabolites. 2021 Dec 22; 12(1).Metabolites2021-12-22T00:00:002021Lipid Alterations in African American Men with Prostate Cancer.Authorship 1379375Authorship 1381032Authorship 138396724204309Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BWPLoS geneticsAcceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet. 2013 Oct; 9(10):e1003900.PLoS Genet2013-10-24T00:00:002013Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization.24316975Terunuma A, Putluri N, Mishra P, Math? EA, Dorsey TH, Yi M, Wallace TA, Issaq HJ, Zhou M, Killian JK, Stevenson HS, Karoly ED, Chan K, Samanta S, Prieto D, Hsu TY, Kurley SJ, Putluri V, Sonavane R, Edelman DC, Wulff J, Starks AM, Yang Y, Kittles RA, Yfantis HG, Lee DH, Ioffe OB, Schiff R, Stephens RM, Meltzer PS, Veenstra TD, Westbrook TF, Sreekumar A, Ambs SThe Journal of clinical investigationMYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis. J Clin Invest. 2014 Jan; 124(1):398-412.J Clin Invest2013-12-09T00:00:002013MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.24338880Bhowmik SK, Putluri V, Kommagani R, Konde SA, Lydon JP, Sreekumar A, Putluri NJournal of mass spectrometry : JMSApplication of 13C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation. J Mass Spectrom. 2013 Dec; 48(12):1270-5.J Mass Spectrom2013-12-01T00:00:002013Application of 13C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation.Authorship 1045912535562082Stork BA, Dean A, Ortiz AR, Saha P, Putluri N, Planas-Silva MD, Mahmud I, Rajapakshe K, Coarfa C, Knapp S, Lorenzi PL, Kemp BE, Turk BE, Scott JW, Means AR, York BMolecular metabolismCalcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism. Mol Metab. 2022 08; 62:101513.Mol Metab2022-05-11T00:00:002022Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism.Authorship 10478041335676822Thaiparambil J, Dong J, Grimm SL, Perera D, Ambati CSR, Putluri V, Robertson MJ, Patel TD, Mistretta B, Gunaratne PH, Kim MP, Yustein JT, Putluri N, Coarfa C, El-Zein RCancer medicineIntegrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer. Cancer Med. 2023 01; 12(1):584-596.Cancer Med2022-06-08T00:00:002022Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer.Authorship 1047999535699798Freudenburg E, Bagheri I, Srinivas S, Martinez A, Putluri N, Klaassen Z, Kamat AM, Konety BR, Kim WY, Dyrskj?t L, McConkey DJ, Freedland SJ, Black PC, Daneshmand S, Catto JWF, Williams SBCancer causes & control : CCCRace reporting and disparities regarding clinical trials in bladder cancer: a systematic review. Cancer Causes Control. 2022 Aug; 33(8):1071-1081.Cancer Causes Control2022-06-14T00:00:002022Race reporting and disparities regarding clinical trials in bladder cancer: a systematic review.Authorship 1048786935736477Kami Reddy KR, Piyarathna DWB, Kamal AHM, Putluri V, Ravi SS, Bollag RJ, Terris MK, Lotan Y, Putluri NMetabolitesLipidomic Profiling Identifies a Novel Lipid Signature Associated with Ethnicity-Specific Disparity of Bladder Cancer. Metabolites. 2022 Jun 14; 12(6).Metabolites2022-06-14T00:00:002022Lipidomic Profiling Identifies a Novel Lipid Signature Associated with Ethnicity-Specific Disparity of Bladder Cancer.Authorship 10494661735764645Tao L, Mohammad MA, Milazzo G, Moreno-Smith M, Patel TD, Zorman B, Badachhape A, Hernandez BE, Wolf AB, Zeng Z, Foster JH, Aloisi S, Sumazin P, Zu Y, Hicks J, Ghaghada KB, Putluri N, Perini G, Coarfa C, Barbieri ENature communicationsMYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma. Nat Commun. 2022 06 28; 13(1):3728.Nat Commun2022-06-28T00:00:002022MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma.Authorship 10499651035799091Gusdon AM, Fu C, Putluri V, Paz AS, Chen H, Ren X, Hassan MK, Dash P, Coarfa C, Putluri N, Choi HA, Savarraj JPJNeurocritical careEarly Systemic Glycolytic Shift After Aneurysmal Subarachnoid Hemorrhage is Associated with Functional Outcomes. Neurocrit Care. 2022 12; 37(3):724-734.Neurocrit Care2022-07-08T00:00:002022Early Systemic Glycolytic Shift After Aneurysmal Subarachnoid Hemorrhage is Associated with Functional Outcomes.Authorship 1050379935816267Fujita Y, Nunez-Rubiano L, Dono A, Bellman A, Shah M, Rodriguez JC, Putluri V, Kamal AHM, Putluri N, Riascos RF, Zhu JJ, Esquenazi Y, Ballester LYJournal of neuro-oncologyIDH1 p.R132H ctDNA and D-2-hydroxyglutarate as CSF biomarkers in patients with IDH-mutant gliomas. J Neurooncol. 2022 Sep; 159(2):261-270.J Neurooncol2022-07-11T00:00:002022IDH1 p.R132H ctDNA and D-2-hydroxyglutarate as CSF biomarkers in patients with IDH-mutant gliomas.Authorship 105740516Authorship 10547824Authorship 10585724Authorship 105937324Authorship 10546871836002187Ahmed KM, Veeramachaneni R, Deng D, Putluri N, Putluri V, Cardenas MF, Wheeler DA, Decker WK, Frederick AI, Kazi S, Sikora AG, Sandulache VC, Frederick MJJournal for immunotherapy of cancerGlutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response. J Immunother Cancer. 2022 08; 10(8).J Immunother Cancer2022-08-01T00:00:002022Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response.36166093Hahn AW, Menk AV, Rivadeneira DB, Augustin RC, Xu M, Li J, Wu X, Mishra AK, Gide TN, Quek C, Zang Y, Spencer CN, Menzies AM, Daniel CR, Hudgens CW, Nowicki T, Haydu LE, Khan MAW, Gopalakrishnan V, Burton EM, Malke J, Simon JM, Bernatchez C, Putluri N, Woodman SE, Vashisht Gopal YN, Guerrieri R, Fischer GM, Wang J, Wani KM, Thompson JF, Lee JE, Hwu P, Ajami N, Gershenwald JE, Long GV, Scolyer RA, Tetzlaff MT, Lazar AJ, Schadendorf D, Wargo JA, Kirkwood JM, DeBerardinis RJ, Liang H, Futreal A, Zhang J, Wilmott JS, Peng W, Davies MA, Delgoffe GM, Najjar YG, McQuade JLClinical cancer research : an official journal of the American Association for Cancer ResearchObesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma. Clin Cancer Res. 2023 01 04; 29(1):154-164.Clin Cancer Res2023-01-04T00:00:002023Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma.36383649Chang CY, You R, Armstrong D, Bandi A, Cheng YT, Burkhardt PM, Becerra-Dominguez L, Madison MC, Tung HY, Zeng Z, Wu Y, Song L, Phillips PE, Porter P, Knight JM, Putluri N, Yuan X, Marcano DC, McHugh EA, Tour JM, Catic A, Maneix L, Burt BM, Lee HS, Corry DB, Kheradmand FScience advancesChronic exposure to carbon black ultrafine particles reprograms macrophage metabolism and accelerates lung cancer. Sci Adv. 2022 11 18; 8(46):eabq0615.Sci Adv2022-11-16T00:00:002022Chronic exposure to carbon black ultrafine particles reprograms macrophage metabolism and accelerates lung cancer.35954173Ravindran A, Krieger KL, Kaushik AK, Hovington H, Mehdi S, Piyarathna DWB, Putluri V, Basil P, Rasaily U, Gu F, Dang T, Choi JM, Sonavane R, Jung SY, Wang L, Mehra R, Weigel NL, Putluri N, Rowley DR, Palapattu GS, Guillemette C, Lacombe L, L?vesque ?, Sreekumar ACellsUridine Diphosphate Glucuronosyl Transferase 2B28 (UGT2B28) Promotes Tumor Progression and Is Elevated in African American Prostate Cancer Patients. Cells. 2022 07 29; 11(15).Cells2022-07-29T00:00:002022Uridine Diphosphate Glucuronosyl Transferase 2B28 (UGT2B28) Promotes Tumor Progression and Is Elevated in African American Prostate Cancer Patients.36621828Thaiparambil J, Amara CS, Sen S, Putluri N, El-Zein RCancer medicineCigarette smoke condensate induces centrosome clustering in normal lung epithelial cells. Cancer Med. 2023 04; 12(7):8499-8509.Cancer Med2023-01-09T00:00:002023Cigarette smoke condensate induces centrosome clustering in normal lung epithelial cells.Authorship 1065877636909201Alghetaa H, Mohammed A, Singh N, Wilson K, Cai G, Putluri N, Nagarkatti M, Nagarkatti PFrontiers in pharmacologyResveratrol attenuates staphylococcal enterotoxin B-activated immune cell metabolism via upregulation of miR-100 and suppression of mTOR signaling pathway. Front Pharmacol. 2023; 14:1106733.Front Pharmacol2023-02-24T00:00:002023Resveratrol attenuates staphylococcal enterotoxin B-activated immune cell metabolism via upregulation of miR-100 and suppression of mTOR signaling pathway.Authorship 10684096Authorship 106826713Authorship 1068502337071431Chakraborty S, Lulla A, Cheng X, Yeo JY, Mandal J, Yang T, Mei X, Saha P, Golonka RM, Yeoh BS, Mell B, Jia W, Putluri V, Piyarathna DWB, Putluri N, Sreekumar A, Meyer K, Vijay-Kumar M, Joe BJournal of hypertensionConjugated bile acids are nutritionally re-programmable antihypertensive metabolites. J Hypertens. 2023 06 01; 41(6):979-994.J Hypertens2023-04-05T00:00:002023Conjugated bile acids are nutritionally re-programmable antihypertensive metabolites.37067510Yang D, Patel S, Szlachcic WJ, Chmielowiec J, Scaduto D, Putluri N, Sreekumar A, Suliburk J, Metzker M, Balasubramanyam A, Borowiak MDiabetesErratum. Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes. Diabetes 2021;70:2419-2429. Diabetes. 2023 Jun 01; 72(6):821.Diabetes2023-06-01T00:00:002023Erratum. Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes. Diabetes 2021;70:2419-2429.37012319Yu W, Chen Y, Putluri N, Osman A, Coarfa C, Putluri V, Kamal AHM, Asmussen JK, Katsonis P, Myers JN, Lai SY, Lu W, Stephan CC, Powell RT, Johnson FM, Skinner HD, Kazi J, Ahmed KM, Hu L, Threet A, Meyer MD, Bankson JA, Wang T, Davis J, Parker KR, Harris MA, Baek ML, Echeverria GV, Qi X, Wang J, Frederick AI, Walsh AJ, Lichtarge O, Frederick MJ, Sandulache VCBritish journal of cancerEvolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state. Br J Cancer. 2023 06; 128(11):2013-2024.Br J Cancer2023-04-03T00:00:002023Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state.true1InstructorInstructorAuthorship 107431910Authorship 107298717Authorship 1073169437448910Zachariah JP, Pena S, Lupo PJ, Putluri N, Penny DJ, Richard MAContemporary clinical trials communicationsEffect of exogenous l-carnitine on aortic stiffness in dyslipidemic adolescents: Design of a quadruple-blind, randomized, controlled interventional trial. Contemp Clin Trials Commun. 2023 Aug; 34:101174.Contemp Clin Trials Commun2023-06-30T00:00:002023Effect of exogenous l-carnitine on aortic stiffness in dyslipidemic adolescents: Design of a quadruple-blind, randomized, controlled interventional trial.37417957Masschelin PM, Saha P, Ochsner SA, Cox AR, Kim KH, Felix JB, Sharp R, Li X, Tan L, Park JH, Wang L, Putluri V, Lorenzi PL, Nuotio-Antar AM, Sun Z, Kaipparettu BA, Putluri N, Moore DD, Summers SA, McKenna NJ, Hartig SMeLifeVitamin B2 enables regulation of fasting glucose availability. Elife. 2023 Jul 07; 12.Elife2023-07-07T00:00:002023Vitamin B2 enables regulation of fasting glucose availability.37296155Nguyen T, Sridaran D, Chouhan S, Weimholt C, Wilson A, Luo J, Li T, Koomen J, Fang B, Putluri N, Sreekumar A, Feng FY, Mahajan K, Mahajan NPNature communicationsHistone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer. Nat Commun. 2023 06 09; 14(1):3357.Nat Commun2023-06-09T00:00:002023Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer.37697947Arunachalam AR, Samuel SS, Mani A, Maynard JP, Stayer KM, Dybbro E, Narayanan S, Biswas A, Pathan S, Soni K, Kamal AHM, Ambati CSR, Putluri N, Desai MS, Thevananther SAmerican journal of physiology. Gastrointestinal and liver physiologyP2Y2 purinergic receptor gene deletion protects mice from bacterial endotoxin and sepsis-associated liver injury and mortality. Am J Physiol Gastrointest Liver Physiol. 2023 11 01; 325(5):G471-G491.Am J Physiol Gastrointest Liver Physiol2023-09-12T00:00:002023P2Y2 purinergic receptor gene deletion protects mice from bacterial endotoxin and sepsis-associated liver injury and mortality.true1ProfessorProfessorAuthorship 107869713true1ProfessorProfessorAuthorship 10798011037758702Nguyen T, Sridaran D, Chouhan S, Weimholt C, Wilson A, Luo J, Li T, Koomen J, Fang B, Putluri N, Sreekumar A, Feng FY, Mahajan K, Mahajan NPNature communicationsAuthor Correction: Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer. 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