YONG XU to Mice
This is a "connection" page, showing publications YONG XU has written about Mice.
Connection Strength
2.422
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Lac-Phe induces hypophagia by inhibiting AgRP neurons in mice. Nat Metab. 2025 Oct; 7(10):2004-2017.
Score: 0.071
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Vestibular neurons link motion sickness, behavioural thermoregulation and metabolic balance in mice. Nat Metab. 2025 Apr; 7(4):742-758.
Score: 0.069
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Serotonin neurons integrate GABA and dopamine inputs to regulate meal initiation. Metabolism. 2025 Feb; 163:156099.
Score: 0.068
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Identification of an ionic mechanism for ERa-mediated rapid excitation in neurons. Sci Adv. 2024 Oct 04; 10(40):eadp0696.
Score: 0.067
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Distinct basal forebrain-originated neural circuits promote homoeostatic feeding and suppress hedonic feeding in male mice. Nat Metab. 2024 Sep; 6(9):1775-1790.
Score: 0.066
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Translational potential of mouse models of human metabolic disease. Cell. 2024 Aug 08; 187(16):4129-4143.
Score: 0.066
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A Light-Responsive Neural Circuit Suppresses Feeding. J Neurosci. 2024 Jul 24; 44(30).
Score: 0.066
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Neural circuits expressing the serotonin 2C receptor regulate memory in mice and humans. Sci Adv. 2024 06 28; 10(26):eadl2675.
Score: 0.066
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Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia. J Clin Invest. 2023 07 17; 133(14).
Score: 0.061
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Hypothalamic Grb10 enhances leptin signalling and promotes weight loss. Nat Metab. 2023 01; 5(1):147-164.
Score: 0.059
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A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nat Neurosci. 2022 05; 25(5):646-658.
Score: 0.056
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Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition. Cell Rep. 2021 12 07; 37(10):110075.
Score: 0.055
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Free-floating Immunostaining of Mouse Brains. J Vis Exp. 2021 10 07; (176).
Score: 0.054
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Barbadin Potentiates Long-Term Effects of Lorcaserin on POMC Neurons and Weight Loss. J Neurosci. 2021 06 30; 41(26):5734-5746.
Score: 0.053
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AgRP neurons trigger long-term potentiation and facilitate food seeking. Transl Psychiatry. 2021 01 05; 11(1):11.
Score: 0.051
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TPH2 in the Dorsal Raphe Nuclei Regulates Energy Balance in a Sex-Dependent Manner. Endocrinology. 2021 01 01; 162(1).
Score: 0.051
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Estrogen receptor-a expressing neurons in the ventrolateral VMH regulate glucose balance. Nat Commun. 2020 05 01; 11(1):2165.
Score: 0.049
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A POMC-originated circuit regulates stress-induced hypophagia, depression, and anhedonia. Mol Psychiatry. 2020 05; 25(5):1006-1021.
Score: 0.047
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TAp63 contributes to sexual dimorphism in POMC neuron functions and energy homeostasis. Nat Commun. 2018 04 18; 9(1):1544.
Score: 0.043
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A neural basis for antagonistic control of feeding and compulsive behaviors. Nat Commun. 2018 01 04; 9(1):52.
Score: 0.042
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Melanocortin 4 receptor is not required for estrogenic regulations on energy homeostasis and reproduction. Metabolism. 2017 05; 70:152-159.
Score: 0.039
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Activation of Serotonin 2C Receptors in Dopamine Neurons Inhibits Binge-like Eating in Mice. Biol Psychiatry. 2017 05 01; 81(9):737-747.
Score: 0.037
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Estrogen Receptor-a in the Medial Amygdala Prevents Stress-Induced Elevations in Blood Pressure in Females. Hypertension. 2016 06; 67(6):1321-30.
Score: 0.037
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PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice. Sci Rep. 2016 Mar 18; 6:23459.
Score: 0.037
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Visualizing estrogen receptor-a-expressing neurons using a new ERa-ZsGreen reporter mouse line. Metabolism. 2016 Apr; 65(4):522-32.
Score: 0.036
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The ERa-PI3K Cascade in Proopiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice. Endocrinology. 2015 Dec; 156(12):4474-91.
Score: 0.036
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Targeting brain estrogen receptor for binge eating. Oncotarget. 2015 Sep 15; 6(27):23044-5.
Score: 0.036
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Apolipoprotein A-IV Inhibits AgRP/NPY Neurons and Activates Pro-Opiomelanocortin Neurons in the Arcuate Nucleus. Neuroendocrinology. 2016; 103(5):476-488.
Score: 0.035
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Meta-chlorophenylpiperazine enhances leptin sensitivity in diet-induced obese mice. Br J Pharmacol. 2015 Jul; 172(14):3510-21.
Score: 0.035
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Progress in the molecular understanding of central regulation of body weight by estrogens. Obesity (Silver Spring). 2015 May; 23(5):919-26.
Score: 0.035
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Estrogens prevent metabolic dysfunctions induced by circadian disruptions in female mice. Endocrinology. 2015 Jun; 156(6):2114-23.
Score: 0.034
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Central nervous control of energy and glucose balance: focus on the central melanocortin system. Ann N Y Acad Sci. 2011 Dec; 1243:1-14.
Score: 0.027
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Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metab. 2011 Oct 05; 14(4):453-65.
Score: 0.027
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A serotonin and melanocortin circuit mediates D-fenfluramine anorexia. J Neurosci. 2010 Nov 03; 30(44):14630-4.
Score: 0.025
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5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. Nat Neurosci. 2010 Dec; 13(12):1457-9.
Score: 0.025
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PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis. Cell Metab. 2010 Jul 07; 12(1):88-95.
Score: 0.025
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5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis. Neuron. 2008 Nov 26; 60(4):582-9.
Score: 0.022
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Regulation of food intake by Connexin43 via adipocyte-sensory neuron electrical synapses. Mol Metab. 2025 Nov; 101:102247.
Score: 0.018
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Prolonged exposure to food odors suppresses feeding via an olfactory bulb-to-hypothalamus circuit. Nat Commun. 2025 Aug 23; 16(1):7892.
Score: 0.018
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Low-dose metformin requires brain Rap1 for its antidiabetic action. Sci Adv. 2025 Aug; 11(31):eadu3700.
Score: 0.018
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The small GTPase Rap1 in POMC neurons regulates leptin actions and glucose metabolism. Mol Metab. 2025 May; 95:102117.
Score: 0.017
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A ?-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites. Cell. 2025 Jan 09; 188(1):175-186.e20.
Score: 0.017
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Loss of transient receptor potential channel 5 causes obesity and postpartum depression. Cell. 2024 Aug 08; 187(16):4176-4192.e17.
Score: 0.016
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TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy. Acta Neuropathol. 2024 03 25; 147(1):61.
Score: 0.016
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An excitatory projection from the basal forebrain to the ventral tegmental area that underlies anorexia-like phenotypes. Neuron. 2024 Feb 07; 112(3):458-472.e6.
Score: 0.016
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The melanocortin action is biased toward protection from weight loss in mice. Nat Commun. 2023 04 17; 14(1):2200.
Score: 0.015
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Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior. Nat Med. 2022 12; 28(12):2537-2546.
Score: 0.015
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Gabra5 plays a sexually dimorphic role in POMC neuron activity and glucose balance. Front Endocrinol (Lausanne). 2022; 13:889122.
Score: 0.014
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An exercise-inducible metabolite that suppresses feeding and obesity. Nature. 2022 06; 606(7915):785-790.
Score: 0.014
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Protein tyrosine phosphatase receptor d serves as the orexigenic asprosin receptor. Cell Metab. 2022 04 05; 34(4):549-563.e8.
Score: 0.014
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Gai/o-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents. Cell Rep. 2021 11 16; 37(7):109997.
Score: 0.014
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Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis. Nat Commun. 2021 08 10; 12(1):4829.
Score: 0.013
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Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding. Nat Commun. 2021 06 10; 12(1):3525.
Score: 0.013
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Rap1 in the VMH regulates glucose homeostasis. JCI Insight. 2021 06 08; 6(11).
Score: 0.013
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Cell lineage tracing links ERa loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).
Score: 0.013
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Asprosin-neutralizing antibodies as a treatment for metabolic syndrome. Elife. 2021 04 27; 10.
Score: 0.013
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REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. Nature. 2021 04; 592(7856):763-767.
Score: 0.013
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Eosinophils attenuate hepatic ischemia-reperfusion injury in mice through ST2-dependent IL-13 production. Sci Transl Med. 2021 02 03; 13(579).
Score: 0.013
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Defining vitamin D receptor expression in the brain using a novel VDRCre mouse. J Comp Neurol. 2021 06; 529(9):2362-2375.
Score: 0.013
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Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice. Nat Commun. 2020 12 11; 11(1):6378.
Score: 0.013
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Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus. Endocrinology. 2020 09 01; 161(9).
Score: 0.013
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Paraventricular hypothalamus mediates diurnal rhythm of metabolism. Nat Commun. 2020 07 30; 11(1):3794.
Score: 0.012
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Profound and redundant functions of arcuate neurons in obesity development. Nat Metab. 2020 08; 2(8):763-774.
Score: 0.012
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17?-estradiol promotes acute refeeding in hungry mice via membrane-initiated ERa signaling. Mol Metab. 2020 12; 42:101053.
Score: 0.012
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Disrupted hypothalamic CRH neuron responsiveness contributes to diet-induced obesity. EMBO Rep. 2020 07 03; 21(7):e49210.
Score: 0.012
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Metabolic dysregulation in the Atp7b-/- Wilson's disease mouse model. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):2076-2083.
Score: 0.012
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GDF5 Promotes White Adipose Tissue Thermogenesis via p38 MAPK Signaling Pathway. DNA Cell Biol. 2019 Nov; 38(11):1303-1312.
Score: 0.012
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Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition. J Clin Invest. 2019 08 12; 129(9):3786-3791.
Score: 0.012
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Identification of a neurocircuit underlying regulation of feeding by stress-related emotional responses. Nat Commun. 2019 08 01; 10(1):3446.
Score: 0.012
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Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis. Nat Commun. 2019 04 12; 10(1):1718.
Score: 0.011
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A lateral hypothalamus to basal forebrain neurocircuit promotes feeding by suppressing responses to anxiogenic environmental cues. Sci Adv. 2019 03; 5(3):eaav1640.
Score: 0.011
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Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Nat Neurosci. 2019 02; 22(2):205-217.
Score: 0.011
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Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1. Diabetes. 2019 02; 68(2):291-304.
Score: 0.011
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Preoptic leptin signaling modulates energy balance independent of body temperature regulation. Elife. 2018 05 15; 7.
Score: 0.011
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NRG1-Fc improves metabolic health via dual hepatic and central action. JCI Insight. 2018 03 08; 3(5).
Score: 0.011
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Arginine reverses growth hormone resistance through the inhibition of toll-like receptor 4-mediated inflammatory pathway. Metabolism. 2018 02; 79:10-23.
Score: 0.010
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Asprosin is a centrally acting orexigenic hormone. Nat Med. 2017 Dec; 23(12):1444-1453.
Score: 0.010
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DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway. Proc Natl Acad Sci U S A. 2017 11 14; 114(46):12196-12201.
Score: 0.010
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Heparin Increases Food Intake through AgRP Neurons. Cell Rep. 2017 Sep 05; 20(10):2455-2467.
Score: 0.010
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Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis. Int J Mol Sci. 2017 Apr 14; 18(4).
Score: 0.010
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SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice. PLoS One. 2016; 11(12):e0168644.
Score: 0.010
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Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight. Diabetes. 2016 09; 65(9):2732-41.
Score: 0.009
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Neuronal Deletion of Ghrelin Receptor Almost Completely Prevents Diet-Induced Obesity. Diabetes. 2016 08; 65(8):2169-78.
Score: 0.009
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New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):3645-50.
Score: 0.009
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Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release. Diabetes. 2016 04; 65(4):1040-9.
Score: 0.009
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An Indirect Action Contributes to C-Fos Induction in Paraventricular Hypothalamic Nucleus by Neuropeptide Y. Sci Rep. 2016 Jan 27; 6:19980.
Score: 0.009
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Hypothalamic Non-AgRP, Non-POMC GABAergic Neurons Are Required for Postweaning Feeding and NPY Hyperphagia. J Neurosci. 2015 Jul 22; 35(29):10440-50.
Score: 0.009
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GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding. J Neurosci. 2015 Feb 25; 35(8):3312-8.
Score: 0.009
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Phloretin promotes adipocyte differentiation in vitro and improves glucose homeostasis in vivo. J Nutr Biochem. 2014 Dec; 25(12):1296-308.
Score: 0.008
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Profound and rapid reduction in body temperature induced by the melanocortin receptor agonists. Biochem Biophys Res Commun. 2014 Aug 22; 451(2):184-9.
Score: 0.008
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Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis. J Clin Invest. 2013 Dec; 123(12):5061-70.
Score: 0.008
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Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons. Cell Metab. 2013 Jul 02; 18(1):86-98.
Score: 0.008
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Bmal1 and ?-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced ?-cell failure in mice. Mol Cell Biol. 2013 Jun; 33(11):2327-38.
Score: 0.008
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Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice. Endocrinology. 2013 Jan; 154(1):150-8.
Score: 0.007
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Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels. Neuron. 2011 Aug 11; 71(3):488-97.
Score: 0.007
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Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus. Proc Natl Acad Sci U S A. 2011 Jun 28; 108(26):10673-8.
Score: 0.007
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Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metab. 2010 Apr 07; 11(4):286-97.
Score: 0.006
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Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis. Endocrinology. 2009 Nov; 150(11):4874-82.
Score: 0.006