PAUL HOPKINS to Adult
This is a "connection" page, showing publications PAUL HOPKINS has written about Adult.
Connection Strength
0.765
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Pharmacokinetic and pharmacodynamic assessment of alirocumab in patients with familial hypercholesterolemia associated with proprotein convertase subtilisin/kexin type 9 gain-of-function or apolipoprotein B loss-of-function mutations. J Clin Lipidol. 2019 Nov - Dec; 13(6):970-978.
Score: 0.035
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Familial hypercholesterolemias: prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol. 2011 Jun; 5(3 Suppl):S9-17.
Score: 0.020
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Chocolate consumption is inversely associated with prevalent coronary heart disease: the National Heart, Lung, and Blood Institute Family Heart Study. Clin Nutr. 2011 Apr; 30(2):182-7.
Score: 0.019
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Chocolate consumption is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the NHLBI Family Heart Study. Clin Nutr. 2011 Feb; 30(1):38-43.
Score: 0.019
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Altered composition of triglyceride-rich lipoproteins and coronary artery disease in a large case-control study. Atherosclerosis. 2009 Dec; 207(2):559-66.
Score: 0.017
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Association of coronary artery calcified plaque with clinical coronary heart disease in the National Heart, Lung, and Blood Institute's Family Heart Study. Am J Cardiol. 2006 Jun 01; 97(11):1564-9.
Score: 0.014
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Sodium bicarbonate cotransporter polymorphisms are associated with baseline and 10-year follow-up blood pressures. Hypertension. 2006 Mar; 47(3):532-6.
Score: 0.014
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Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP-CARE): A protocol for a randomized clinical trial. Acta Anaesthesiol Scand. 2025 07; 69(6):e70040.
Score: 0.013
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Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED-CARE): A protocol for a randomized clinical trial. Acta Anaesthesiol Scand. 2025 05; 69(5):e70022.
Score: 0.013
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Linkage of serum creatinine and glomerular filtration rate to chromosome 2 in Utah pedigrees. Am J Hypertens. 2004 Jun; 17(6):511-5.
Score: 0.012
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Obesity does not alter vascular function and handgrip exercise hemodynamics in middle-aged patients with hypertension. Am J Physiol Regul Integr Comp Physiol. 2024 01 01; 326(1):R1-R9.
Score: 0.012
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Coronary artery disease risk in familial combined hyperlipidemia and familial hypertriglyceridemia: a case-control comparison from the National Heart, Lung, and Blood Institute Family Heart Study. Circulation. 2003 Aug 05; 108(5):519-23.
Score: 0.011
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Linkage of creatinine clearance to chromosome 10 in Utah pedigrees replicates a locus for end-stage renal disease in humans and renal failure in the fawn-hooded rat. Kidney Int. 2002 Oct; 62(4):1143-8.
Score: 0.011
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Angiotensinogen genotype affects renal and adrenal responses to angiotensin II in essential hypertension. Circulation. 2002 Apr 23; 105(16):1921-7.
Score: 0.011
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Genetic Predictors of Salt Sensitivity of Blood Pressure: The Additive Impact of 2 Hits in the Same Biological Pathway. Hypertension. 2021 12; 78(6):1809-1817.
Score: 0.010
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The Role of Thyroid in Renovascular Function: Independent Association of Serum TSH With Renal Plasma Flow. J Clin Endocrinol Metab. 2021 08 18; 106(9):e3327-e3334.
Score: 0.010
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Characterizing a Common CERS2 Polymorphism in a Mouse Model of Metabolic Disease and in Subjects from the Utah CAD Study. J Clin Endocrinol Metab. 2021 07 13; 106(8):e3098-e3109.
Score: 0.010
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Evaluation of coronary risk factors in patients with heterozygous familial hypercholesterolemia. Am J Cardiol. 2001 Mar 01; 87(5):547-53.
Score: 0.010
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Usefulness of cardiovascular family history data for population-based preventive medicine and medical research (the Health Family Tree Study and the NHLBI Family Heart Study). Am J Cardiol. 2001 Jan 15; 87(2):129-35.
Score: 0.010
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Carbohydrate and fat intake associated with risk of metabolic diseases through epigenetics of CPT1A. Am J Clin Nutr. 2020 11 11; 112(5):1200-1211.
Score: 0.010
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The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study. Ann Intern Med. 2020 07 07; 173(1):10-20.
Score: 0.009
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Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease. J Clin Invest. 2020 03 02; 130(3):1363-1376.
Score: 0.009
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Efficacy and Safety of Alirocumab in Patients With Autosomal Dominant Hypercholesterolemia Associated With Proprotein Convertase Subtilisin/Kexin Type 9 Gain-of-Function or Apolipoprotein B Loss-of-Function Mutations. Am J Cardiol. 2020 03 15; 125(6):880-886.
Score: 0.009
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Salt restriction lowers blood pressure at rest and during exercise without altering peripheral hemodynamics in hypertensive individuals. Am J Physiol Heart Circ Physiol. 2019 12 01; 317(6):H1194-H1202.
Score: 0.009
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Evidence for a third genetic locus causing familial hypercholesterolemia. A non-LDLR, non-APOB kindred. J Lipid Res. 1999 Jun; 40(6):1113-22.
Score: 0.009
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A novel LDLR mutation, H190Y, in a Utah kindred with familial hypercholesterolemia. J Hum Genet. 1999; 44(6):364-7.
Score: 0.008
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Lipoprotein(a) interactions with lipid and non-lipid risk factors in patients with early onset coronary artery disease: results from the NHLBI Family Heart Study. Atherosclerosis. 1998 Dec; 141(2):333-45.
Score: 0.008
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Alirocumab efficacy in patients with double heterozygous, compound heterozygous, or homozygous familial hypercholesterolemia. J Clin Lipidol. 2018 Mar - Apr; 12(2):390-396.e8.
Score: 0.008
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Striatin Gene Polymorphic Variants Are Associated With Salt Sensitive Blood Pressure in Normotensives and Hypertensives. Am J Hypertens. 2017 Dec 08; 31(1):124-131.
Score: 0.008
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Dysregulated aldosterone secretion in persons of African descent with endothelin-1 gene variants. JCI Insight. 2017 12 07; 2(23).
Score: 0.008
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Sex Differences in Blood HDL-c, the Total Cholesterol/HDL-c Ratio, and Palmitoleic Acid are Not Associated with Variants in Common Candidate Genes. Lipids. 2017 Dec; 52(12):969-980.
Score: 0.008
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The association between hypercholesterolemia and sitosterolemia, and report of a sitosterolemia kindred. J Clin Lipidol. 2018 Jan - Feb; 12(1):152-161.
Score: 0.008
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Weight and Metabolic Outcomes 12 Years after Gastric Bypass. N Engl J Med. 2017 09 21; 377(12):1143-1155.
Score: 0.008
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Efficacy of alirocumab in 1191 patients with a wide spectrum of mutations in genes causative for familial hypercholesterolemia. J Clin Lipidol. 2017 Nov - Dec; 11(6):1338-1346.e7.
Score: 0.008
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Expression of Metabolic Syndrome in Women with Severe Obesity. Metab Syndr Relat Disord. 2017 08; 15(6):283-290.
Score: 0.008
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Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36. J Lipid Res. 2016 12; 57(12):2176-2184.
Score: 0.007
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Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis. J Am Heart Assoc. 2016 09 28; 5(10).
Score: 0.007
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When body mass index fails to measure up: perinephric and periumbilical fat as predictors of operative risk. Am J Surg. 2016 Dec; 212(6):1039-1046.
Score: 0.007
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Hypertension, dyslipidemia, and insulin resistance: links in a chain or spokes on a wheel? Curr Opin Lipidol. 1996 Aug; 7(4):241-53.
Score: 0.007
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Assessment of postprandial triglycerides in clinical practice: Validation in a general population and coronary heart disease patients. J Clin Lipidol. 2016 Sep-Oct; 10(5):1163-71.
Score: 0.007
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Blunted renal vascular response to angiotensin II is associated with a common variant of the angiotensinogen gene and obesity. J Hypertens. 1996 Feb; 14(2):199-207.
Score: 0.007
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Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects. Circulation. 2015 Nov 10; 132(19):1825-33.
Score: 0.007
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A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics. Metabolism. 2015 Dec; 64(12):1674-81.
Score: 0.007
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Higher plasma homocyst(e)ine and increased susceptibility to adverse effects of low folate in early familial coronary artery disease. Arterioscler Thromb Vasc Biol. 1995 Sep; 15(9):1314-20.
Score: 0.007
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Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation. J Physiol. 2015 Sep 15; 593(18):4259-73.
Score: 0.007
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Plasma homocyst(e)ine as a risk factor for early familial coronary artery disease. Clin Chem. 1994 Apr; 40(4):552-61.
Score: 0.006
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Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response. Hum Genet. 2014 Jul; 133(7):919-30.
Score: 0.006
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Hemodynamic and echocardiographic profiles in African American compared with White offspring of hypertensive parents: the HyperGEN study. Am J Hypertens. 2014 Jan; 27(1):21-6.
Score: 0.006
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Predictors of plasma and urinary catecholamine levels in normotensive and hypertensive men and women. J Hum Hypertens. 2014 May; 28(5):292-7.
Score: 0.006
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Sex-specific associations between screen time and lipoprotein subfractions. Int J Sport Nutr Exerc Metab. 2014 Feb; 24(1):59-69.
Score: 0.006
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Diagnosing heterozygous familial hypercholesterolemia using new practical criteria validated by molecular genetics. Am J Cardiol. 1993 Jul 15; 72(2):171-6.
Score: 0.006
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Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity. Hum Genet. 2013 Apr; 132(4):405-13.
Score: 0.006
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Genetic analysis of 16 NMR-lipoprotein fractions in humans, the GOLDN study. Lipids. 2013 Feb; 48(2):155-65.
Score: 0.005
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Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network. Nutr Metab Cardiovasc Dis. 2013 Oct; 23(10):987-94.
Score: 0.005
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Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate. PLoS One. 2012; 7(10):e48663.
Score: 0.005
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The relation between erythrocyte trans fat and triglyceride, VLDL- and HDL-cholesterol concentrations depends on polyunsaturated fat. PLoS One. 2012; 7(10):e47430.
Score: 0.005
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Health benefits of gastric bypass surgery after 6 years. JAMA. 2012 Sep 19; 308(11):1122-31.
Score: 0.005
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Adipocyte iron regulates adiponectin and insulin sensitivity. J Clin Invest. 2012 Oct; 122(10):3529-40.
Score: 0.005
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The effect of CYP7A1 polymorphisms on lipid responses to fenofibrate. J Cardiovasc Pharmacol. 2012 Mar; 59(3):254-9.
Score: 0.005
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A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network. Pharmacogenet Genomics. 2012 Mar; 22(3):191-7.
Score: 0.005
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Delivery of monochorionic twins in the absence of complications: analysis of neonatal outcomes and costs. Am J Obstet Gynecol. 2012 Mar; 206(3):257.e1-7.
Score: 0.005
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A clustering analysis of lipoprotein diameters in the metabolic syndrome. Lipids Health Dis. 2011 Dec 19; 10:237.
Score: 0.005
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A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI. J Nutr. 2011 Dec; 141(12):2219-25.
Score: 0.005
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High-fat meal effect on LDL, HDL, and VLDL particle size and number in the Genetics of Lipid-Lowering Drugs and Diet Network (GOLDN): an interventional study. Lipids Health Dis. 2011 Oct 18; 10:181.
Score: 0.005
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Type III dyslipoproteinemia in patients heterozygous for familial hypercholesterolemia and apolipoprotein E2. Evidence for a gene-gene interaction. Arterioscler Thromb. 1991 Sep-Oct; 11(5):1137-46.
Score: 0.005
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Lipoprotein lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetS. Lipids Health Dis. 2011 Aug 19; 10:143.
Score: 0.005
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Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol. 2011 Jun; 5(3 Suppl):S1-8.
Score: 0.005
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Evaluation of the gene-age interactions in HDL cholesterol, LDL cholesterol, and triglyceride levels: the impact of the SORT1 polymorphism on LDL cholesterol levels is age dependent. Atherosclerosis. 2011 Jul; 217(1):139-41.
Score: 0.005
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Association of gene variants with lipid levels in response to fenofibrate is influenced by metabolic syndrome status. Atherosclerosis. 2011 Apr; 215(2):435-9.
Score: 0.005
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Selected outcomes of thumb replantation after isolated thumb amputation injury. J Hand Surg Am. 2010 Sep; 35(9):1485-90.
Score: 0.005
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Increased levels of T cell granzyme b in bronchiolitis obliterans syndrome are not suppressed adequately by current immunosuppressive regimens. Clin Exp Immunol. 2009 Nov; 158(2):230-6.
Score: 0.004
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Predictive value of a short dietary questionnaire for changes in serum lipids in high-risk Utah families. Am J Clin Nutr. 1989 Aug; 50(2):292-300.
Score: 0.004
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Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese. Obesity (Silver Spring). 2010 Jan; 18(1):121-30.
Score: 0.004
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Identification of a pleiotropic locus on chromosome 7q for a composite left ventricular wall thickness factor and body mass index: the HyperGEN Study. BMC Med Genet. 2009 May 09; 10:40.
Score: 0.004
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Cancer incidence and mortality after gastric bypass surgery. Obesity (Silver Spring). 2009 Apr; 17(4):796-802.
Score: 0.004
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Family history as an independent risk factor for incident coronary artery disease in a high-risk cohort in Utah. Am J Cardiol. 1988 Oct 01; 62(10 Pt 1):703-7.
Score: 0.004
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Smoking, inflammatory patterns and postprandial hypertriglyceridemia. Atherosclerosis. 2009 Apr; 203(2):633-9.
Score: 0.004
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The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN studyboxs. J Lipid Res. 2008 Aug; 49(8):1839-45.
Score: 0.004
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Association of the FTO gene with BMI. Obesity (Silver Spring). 2008 Apr; 16(4):902-4.
Score: 0.004
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The genetic architecture of fasting plasma triglyceride response to fenofibrate treatment. Eur J Hum Genet. 2008 May; 16(5):603-13.
Score: 0.004
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Circulating soluble ICAM-1 levels shows linkage to ICAM gene cluster region on chromosome 19: the NHLBI Family Heart Study follow-up examination. Atherosclerosis. 2008 Jul; 199(1):172-8.
Score: 0.004
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Erythrocyte fatty acid composition and the metabolic syndrome: a National Heart, Lung, and Blood Institute GOLDN study. Clin Chem. 2008 Jan; 54(1):154-62.
Score: 0.004
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Circulating MCP-1 levels shows linkage to chemokine receptor gene cluster on chromosome 3: the NHLBI family heart study follow-up examination. Genes Immun. 2007 Dec; 8(8):684-90.
Score: 0.004
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Hostile personality traits and coronary artery calcification in middle-aged and older married couples: different effects for self-reports versus spouse ratings. Psychosom Med. 2007 Jun; 69(5):441-8.
Score: 0.004
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A whole genome scan for pulse pressure/stroke volume ratio in African Americans: the HyperGEN study. Am J Hypertens. 2007 Apr; 20(4):398-402.
Score: 0.004
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Lack of association of glutamate decarboxylase 2 gene polymorphisms with severe obesity in utah. Obesity (Silver Spring). 2006 Apr; 14(4):650-5.
Score: 0.003
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Evidence of QTL on 15q21 for high-density lipoprotein cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study (NHLBI FHS). Atherosclerosis. 2007 Jan; 190(1):232-7.
Score: 0.003
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Familial clustering for features of the metabolic syndrome: the National Heart, Lung, and Blood Institute (NHLBI) Family Heart Study. Diabetes Care. 2006 Mar; 29(3):631-6.
Score: 0.003
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Design and rationale of the Utah obesity study. A study to assess morbidity following gastric bypass surgery. Contemp Clin Trials. 2005 Oct; 26(5):534-51.
Score: 0.003
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Left atrial systolic force and cardiac markers of preclinical disease in hypertensive patients: the Hypertension Genetic Epidemiology Network (HyperGEN) Study. Am J Hypertens. 2005 Jul; 18(7):899-905.
Score: 0.003
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Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart Study. Circulation. 2005 Jun 07; 111(22):2921-6.
Score: 0.003
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Dietary linolenic acid and adjusted QT and JT intervals in the National Heart, Lung, and Blood Institute Family Heart study. J Am Coll Cardiol. 2005 May 17; 45(10):1716-22.
Score: 0.003
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A genome scan for linkage with aortic root diameter in hypertensive African Americans and whites in the Hypertension Genetic Epidemiology Network (HyperGEN) study. Am J Hypertens. 2005 May; 18(5 Pt 1):627-32.
Score: 0.003
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Aortic valve sclerosis is associated with preclinical cardiovascular disease in hypertensive adults: the Hypertension Genetic Epidemiology Network study. J Hypertens. 2005 Apr; 23(4):867-73.
Score: 0.003
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Dietary linolenic acid is associated with a lower prevalence of hypertension in the NHLBI Family Heart Study. Hypertension. 2005 Mar; 45(3):368-73.
Score: 0.003
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Model-fitting and linkage analysis of sodium-lithium countertransport. Eur J Hum Genet. 2004 Dec; 12(12):1055-61.
Score: 0.003
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Association of inappropriate left ventricular mass with systolic and diastolic dysfunction: the HyperGEN study. Am J Hypertens. 2004 Sep; 17(9):828-33.
Score: 0.003
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TXNIP gene not associated with familial combined hyperlipidemia in the NHLBI Family Heart Study. Atherosclerosis. 2004 Jun; 174(2):357-62.
Score: 0.003
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Differences in left ventricular structure between black and white hypertensive adults: the Hypertension Genetic Epidemiology Network study. Hypertension. 2004 Jun; 43(6):1182-8.
Score: 0.003
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The Arg16Gly polymorphism of the beta2-adrenergic receptor and left ventricular systolic function. Am J Hypertens. 2003 Nov; 16(11 Pt 1):945-51.
Score: 0.003
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Influence of fat-free mass on detection of appropriateness of left ventricular mass: the HyperGEN Study. J Hypertens. 2003 Sep; 21(9):1747-52.
Score: 0.003
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Genome-wide multipoint parametric linkage analysis of pulse pressure in large, extended utah pedigrees. Hypertension. 2003 Sep; 42(3):322-8.
Score: 0.003
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Relation of insulin to left ventricular geometry and function in African American and white hypertensive adults: the HyperGEN study. Am J Hypertens. 2002 Dec; 15(12):1029-35.
Score: 0.003
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A genome scan for loci influencing anti-atherogenic serum bilirubin levels. Eur J Hum Genet. 2002 Sep; 10(9):539-46.
Score: 0.003
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Blood pressure responses to acute stress and left ventricular mass (The Hypertension Genetic Epidemiology Network Study). Am J Cardiol. 2002 Mar 01; 89(5):536-40.
Score: 0.003
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Sibling correlation of left ventricular mass and geometry in hypertensive African Americans and whites: the HyperGEN study. Hypertension Genetic Epidemiology Network. Am J Hypertens. 2001 Dec; 14(12):1226-30.
Score: 0.003
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Left ventricular systolic dysfunction in a biracial sample of hypertensive adults: The Hypertension Genetic Epidemiology Network (HyperGEN) Study. Hypertension. 2001 Sep; 38(3):417-23.
Score: 0.003
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Relationship between left ventricular diastolic relaxation and systolic function in hypertension: The Hypertension Genetic Epidemiology Network (HyperGEN) Study. Hypertension. 2001 Sep; 38(3):424-8.
Score: 0.003
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Familial aggregation of QT-interval variability in a general population: results from the NHLBI Family Heart Study. Clin Genet. 2001 Mar; 59(3):171-7.
Score: 0.002
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Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study. Atherosclerosis. 2001 Feb 15; 154(3):681-9.
Score: 0.002
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Effect of type 2 diabetes mellitus on left ventricular geometry and systolic function in hypertensive subjects: Hypertension Genetic Epidemiology Network (HyperGEN) study. Circulation. 2001 Jan 02; 103(1):102-7.
Score: 0.002
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Genetic localization to chromosome 1p32 of the third locus for familial hypercholesterolemia in a Utah kindred. Arterioscler Thromb Vasc Biol. 2000 Apr; 20(4):1089-93.
Score: 0.002
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Co-segregation of elevated LDL with a novel mutation (D92K) of the LDL receptor in a kindred with multiple lipoprotein abnormalities. J Hum Genet. 2000; 45(3):154-8.
Score: 0.002
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Association of genetic variations in apolipoprotein B with hypercholesterolemia, coronary artery disease, and receptor binding of low density lipoproteins. J Lipid Res. 1997 Jul; 38(7):1361-73.
Score: 0.002
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Evidence for a major gene elevating serum bilirubin concentration in Utah pedigrees. Arterioscler Thromb Vasc Biol. 1996 Aug; 16(8):912-7.
Score: 0.002
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Molecular basis of human hypertension: role of angiotensinogen. Cell. 1992 Oct 02; 71(1):169-80.
Score: 0.001
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Prevention of familial cardiovascular disease by screening for family history and lipids in youths. Clin Chem. 1992 Aug; 38(8B Pt 2):1555-60.
Score: 0.001
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Evidence for gene-environmental interactions in Utah families with hypertension, dyslipidaemia and early coronary heart disease. Clin Exp Pharmacol Physiol Suppl. 1992; 20:1-6.
Score: 0.001
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Effects of three genetic loci in a pedigree with multiple lipoprotein phenotypes. Arterioscler Thromb. 1991 Sep-Oct; 11(5):1349-55.
Score: 0.001
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Predictors of an increased risk of future hypertension in Utah. A screening analysis. Hypertension. 1991 Jun; 17(6 Pt 2):969-76.
Score: 0.001
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Family-oriented nutrition intervention for a lipid clinic population. J Am Diet Assoc. 1991 Jan; 91(1):57-65.
Score: 0.001
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A prospective study of sodium-lithium countertransport and hypertension in Utah. Hypertension. 1991 Jan; 17(1):1-7.
Score: 0.001
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Genetic traits related to hypertension and electrolyte metabolism. Hypertension. 1991 Jan; 17(1 Suppl):I69-73.
Score: 0.001
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Concordant dyslipidemia, hypertension and early coronary disease in Utah families. Klin Wochenschr. 1990; 68 Suppl 20:53-9.
Score: 0.001
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Genetic heritability and common environmental components of resting and stressed blood pressures, lipids, and body mass index in Utah pedigrees and twins. Am J Epidemiol. 1989 Mar; 129(3):625-38.
Score: 0.001
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Familial dyslipidemic hypertension. Evidence from 58 Utah families for a syndrome present in approximately 12% of patients with essential hypertension. JAMA. 1988 Jun 24; 259(24):3579-86.
Score: 0.001