KE-HE RUAN to Cyclooxygenase 2
This is a "connection" page, showing publications KE-HE RUAN has written about Cyclooxygenase 2.
Connection Strength
2.348
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Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1. Arch Biochem Biophys. 2016 08 01; 603:29-37.
Score: 0.497
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Relationship of the Topological Distances and Activities between mPGES-1 and COX-2 versus COX-1: Implications of the Different Post-Translational Endoplasmic Reticulum Organizations of COX-1 and COX-2. Biochemistry. 2015 Jun 16; 54(23):3707-15.
Score: 0.465
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Inducible COX-2 dominates over COX-1 in prostacyclin biosynthesis: mechanisms of COX-2 inhibitor risk to heart disease. Life Sci. 2011 Jan 03; 88(1-2):24-30.
Score: 0.338
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Large-scale expression, purification, and characterization of an engineered prostacyclin-synthesizing enzyme with therapeutic potential. Arch Biochem Biophys. 2008 Dec 01; 480(1):41-50.
Score: 0.293
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Latest advancements in the study of the relationship between NSAIDs and three prostaglandin E2 synthases. Future Med Chem. 2023 09; 15(17):1549-1552.
Score: 0.206
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Latest progress in the development of cyclooxygenase-2 pathway inhibitors targeting microsomal prostaglandin E2 synthase-1. Future Med Chem. 2022 03; 14(6):385-388.
Score: 0.184
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How can we address the controversies surrounding the use of NSAIDS in neurodegeneration? Future Med Chem. 2016 07; 8(11):1153-5.
Score: 0.125
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COX-2-10aa-PGIS gene therapy improves erectile function in rats after cavernous nerve injury. J Sex Med. 2013 Jun; 10(6):1476-87.
Score: 0.100
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Engineering of a novel hybrid enzyme: an anti-inflammatory drug target with triple catalytic activities directly converting arachidonic acid into the inflammatory prostaglandin E2. Protein Eng Des Sel. 2009 Dec; 22(12):733-40.
Score: 0.079
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Prunella stica inhibits the proliferation but not the prostaglandin production of Ishikawa cells. Life Sci. 2006 Jun 27; 79(5):436-41.
Score: 0.061