GREG CUNY to Models, Molecular
This is a "connection" page, showing publications GREG CUNY has written about Models, Molecular.
Connection Strength
0.765
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Discovery of LRRK2 inhibitors using sequential in silico joint pharmacophore space (JPS) and ensemble docking. Bioorg Med Chem Lett. 2015 Jul 01; 25(13):2713-9.
Score: 0.096
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Synthesis, in vitro evaluation and cocrystal structure of 4-oxo-[1]benzopyrano[4,3-c]pyrazole Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase (CpIMPDH) inhibitors. J Med Chem. 2014 Dec 26; 57(24):10544-50.
Score: 0.093
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Optimization of tricyclic Nec-3 necroptosis inhibitors for in vitro liver microsomal stability. Bioorg Med Chem Lett. 2012 Sep 01; 22(17):5685-8.
Score: 0.079
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Synthesis of tetracyclic indoles via intramolecular a-arylation of ketones. J Org Chem. 2012 Apr 20; 77(8):4123-30.
Score: 0.078
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Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors. Bioorg Med Chem Lett. 2012 Mar 01; 22(5):2015-9.
Score: 0.077
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Structure-activity relationship study of 2,4-diaminothiazoles as Cdk5/p25 kinase inhibitors. Bioorg Med Chem Lett. 2011 Apr 01; 21(7):2098-101.
Score: 0.072
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Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding. ACS Infect Dis. 2025 Feb 14; 11(2):442-452.
Score: 0.047
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Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents. J Med Chem. 2018 06 14; 61(11):4739-4756.
Score: 0.030
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Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors. Chem Biol. 2015 Sep 17; 22(9):1174-84.
Score: 0.025
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A new class of small molecule inhibitor of BMP signaling. PLoS One. 2013; 8(4):e62721.
Score: 0.021
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Type II kinase inhibitors show an unexpected inhibition mode against Parkinson's disease-linked LRRK2 mutant G2019S. Biochemistry. 2013 Mar 12; 52(10):1725-36.
Score: 0.021
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Fluorescence polarization assay for inhibitors of the kinase domain of receptor interacting protein 1. Anal Biochem. 2012 Aug 15; 427(2):164-74.
Score: 0.020
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Characterization of the 8-hydroxyquinoline scaffold for inhibitors of West Nile virus serine protease. Antiviral Res. 2012 Apr; 94(1):18-24.
Score: 0.019
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Kinetic, mechanistic, and structural modeling studies of truncated wild-type leucine-rich repeat kinase 2 and the G2019S mutant. Biochemistry. 2011 Nov 01; 50(43):9399-408.
Score: 0.019
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Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin. PLoS One. 2010 May 07; 5(5):e10504.
Score: 0.017
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Improving binding specificity of pharmacological chaperones that target mutant superoxide dismutase-1 linked to familial amyotrophic lateral sclerosis using computational methods. J Med Chem. 2010 Apr 08; 53(7):2709-18.
Score: 0.017
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The structural basis of Cryptosporidium -specific IMP dehydrogenase inhibitor selectivity. J Am Chem Soc. 2010 Feb 03; 132(4):1230-1.
Score: 0.017
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Small molecules that enhance the catalytic efficiency of HLA-DM. J Immunol. 2006 Apr 01; 176(7):4208-20.
Score: 0.013
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Ring opening cross-metathesis on solid support: a combinatorial library synthesis of highly functionalized cyclopentanes. Mol Divers. 1997-1998; 3(3):173-9.
Score: 0.007