JOSEPHDUMANJOSEPH DUMAN0.000000000000000.000000000000004814DUMAN, JOSEPHAssistant Professorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson25424900Liebscher I, Ackley B, Ara? D, Ariestanti DM, Aust G, Bae BI, Bista BR, Bridges JP, Duman JG, Engel FB, Giera S, Goffinet AM, Hall RA, Hamann J, Hartmann N, Lin HH, Liu M, Luo R, Mogha A, Monk KR, Peeters MC, Pr?mel S, Ressl S, Schi?th HB, Sigoillot SM, Song H, Talbot WS, Tall GG, White JP, Wolfrum U, Xu L, Piao XAnnals of the New York Academy of SciencesNew functions and signaling mechanisms for the class of adhesion G protein-coupled receptors. Ann N Y Acad Sci. 2014 Dec; 1333:43-64.Ann N Y Acad Sci2014-11-25T00:00:002014New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors.Authorship 883941Authorship 185372Authorship 338243Anesthesiology & PeriOperative MedicineExperimental Radiation OncologyRadiation OncologyMD AndersonWEIZHOUWEI ZHOU9313ZHOU, WEIInstructorHUI-LINPANHUI-LIN PAN9317PAN, HUI-LINProfessorDAVID RANDALLGROSSHANSDAVID RANDALL GROSSHANS9270GROSSHANS, DAVID RANDALLAssociate ProfessorAuthorship 860421Authorship 303674126003445Duman JG, Mulherkar S, Tu YK, X Cheng J, Tolias KFNeuroscience lettersMechanisms for spatiotemporal regulation of Rho-GTPase signaling at synapses. Neurosci Lett. 2015 Aug 05; 601:4-10.Neurosci Lett2015-05-21T00:00:002015Mechanisms for spatiotemporal regulation of Rho-GTPase signaling at synapses.74Professor10Assistant Professor65Interim Chair54Instructor14Associate Professor3Adjunct Associate Professor47Distinguished Service Professor11884524Duman JG, Pathak NJ, Ladinsky MS, McDonald KL, Forte JGJournal of cell scienceThree-dimensional reconstruction of cytoplasmic membrane networks in parietal cells. J Cell Sci. 2002 Mar 15; 115(Pt 6):1251-8.J Cell Sci2002-03-15T00:00:002002Three-dimensional reconstruction of cytoplasmic membrane networks in parietal cells.11886591Duman JG, Singh G, Lee GY, Machen TE, Forte JGTraffic (Copenhagen, Denmark)Ca(2+) and Mg(2+)/ATP independently trigger homotypic membrane fusion in gastric secretory membranes. Traffic. 2002 Mar; 3(3):203-17.Traffic2002-03-01T00:00:002002Ca(2+) and Mg(2+)/ATP independently trigger homotypic membrane fusion in gastric secretory membranes.12105856Karvar S, Yao X, Duman JG, Hybiske K, Liu Y, Forte JGGastroenterologyIntracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells. Gastroenterology. 2002 Jul; 123(1):281-90.Gastroenterology2002-07-01T00:00:002002Intracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells.Authorship 322495126881134Duman JG, Tu YK, Tolias KFNeural plasticityEmerging Roles of BAI Adhesion-GPCRs in Synapse Development and Plasticity. Neural Plast. 2016; 2016:8301737.Neural Plast2016-01-04T00:00:002016Emerging Roles of BAI Adhesion-GPCRs in Synapse Development and Plasticity.16787398Duman JG, Chen L, Palmer AE, Hille BTraffic (Copenhagen, Denmark)Contributions of intracellular compartments to calcium dynamics: implicating an acidic store. Traffic. 2006 Jul; 7(7):859-72.Traffic2006-07-01T00:00:002006Contributions of intracellular compartments to calcium dynamics: implicating an acidic store.One Baylor PlazaHouston, 77030TX23184982Dickson EJ, Duman JG, Moody MW, Chen L, Hille BProceedings of the National Academy of Sciences of the United States of AmericaOrai-STIM-mediated Ca2+ release from secretory granules revealed by a targeted Ca2+ and pH probe. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):E3539-48.Proc Natl Acad Sci U S A2012-11-26T00:00:002012Orai-STIM-mediated Ca2+ release from secretory granules revealed by a targeted Ca2+ and pH probe.18347082Duman JG, Chen L, Hille BThe Journal of general physiologyCalcium transport mechanisms of PC12 cells. J Gen Physiol. 2008 Apr; 131(4):307-23.J Gen Physiol2008-03-17T00:00:002008Calcium transport mechanisms of PC12 cells.Authorship 785189127780038Duman JG, Tolias KFDevelopmental cellRhoGTPases Spread the Word for Synaptic Crosstalk. Dev Cell. 2016 10 24; 39(2):136-138.Dev Cell2016-10-24T00:00:002016RhoGTPases Spread the Word for Synaptic Crosstalk.23595754Duman JG, Tzeng CP, Tu YK, Munjal T, Schwechter B, Ho TS, Tolias KFThe Journal of neuroscience : the official journal of the Society for NeuroscienceThe adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites. J Neurosci. 2013 Apr 17; 33(16):6964-78.J Neurosci2013-04-17T00:00:002013The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites.Authorship 103265212842832Duman JG, Forte JGAmerican journal of physiology. Cell physiologyWhat is the role of SNARE proteins in membrane fusion? Am J Physiol Cell Physiol. 2003 Aug; 285(2):C237-49.Am J Physiol Cell Physiol2003-08-01T00:00:002003What is the role of SNARE proteins in membrane fusion?21530608Tolias KF, Duman JG, Um KProgress in neurobiologyControl of synapse development and plasticity by Rho GTPase regulatory proteins. Prog Neurobiol. 2011 Jul; 94(2):133-48.Prog Neurobiol2011-04-22T00:00:002011Control of synapse development and plasticity by Rho GTPase regulatory proteins.Authorship 8792503Authorship 8842801Authorship 885651829045710Wilke C, Grosshans D, Duman J, Brown P, Li JNeuro-oncologyRadiation-induced cognitive toxicity: pathophysiology and interventions to reduce toxicity in adults. Neuro Oncol. 2018 04 09; 20(5):597-607.Neuro Oncol2018-04-09T00:00:002018Radiation-induced cognitive toxicity: pathophysiology and interventions to reduce toxicity in adults.29112734Duman JG, Dinh J, Zhou W, Cham H, Mavratsas VC, Pave?kovic M, Mulherkar S, McGovern SL, Tolias KF, Grosshans DRNeuro-oncologyMemantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses. Neuro Oncol. 2018 04 09; 20(5):655-665.Neuro Oncol2018-04-09T00:00:002018Memantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses.29660023Zhang D, Zhou W, Lam TT, Weng C, Bronk L, Ma D, Wang Q, Duman JG, Dougherty PM, Grosshans DRNeuro-oncologyRadiation induces age-dependent deficits in cortical synaptic plasticity. Neuro Oncol. 2018 08 02; 20(9):1207-1214.Neuro Oncol2018-08-02T00:00:002018Radiation induces age-dependent deficits in cortical synaptic plasticity.JEFFREYMAGEEJEFFREY MAGEE13708MAGEE, JEFFREYProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Distinguished Service ProfessorDistinguished Service ProfessorD013569Anatomy1765130.718689SynapsesD049229Anatomy35590.952304Dendritic SpinesD020741Chemicals & Drugs1001770.878013rho GTP-Binding ProteinsD020662Chemicals & Drugs1131600.890369Guanine Nucleotide Exchange FactorsAuthorship 9310012Authorship 935938930120207Tu YK, Duman JG, Tolias KFThe Journal of neuroscience : the official journal of the Society for NeuroscienceThe Adhesion-GPCR BAI1 Promotes Excitatory Synaptogenesis by Coordinating Bidirectional Trans-synaptic Signaling. J Neurosci. 2018 09 26; 38(39):8388-8406.J Neurosci2018-08-17T00:00:002018The Adhesion-GPCR BAI1 Promotes Excitatory Synaptogenesis by Coordinating Bidirectional Trans-synaptic Signaling.30610205Wang L, Pang K, Han K, Adamski CJ, Wang W, He L, Lai JK, Bondar VV, Duman JG, Richman R, Tolias KF, Barth P, Palzkill T, Liu Z, Holder JL, Zoghbi HYMolecular psychiatryAn autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function. Mol Psychiatry. 2020 10; 25(10):2534-2555.Mol Psychiatry2019-01-04T00:00:002019An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function.JEFFREYYAUJEFFREY YAU0.000000000000000.000000000000005694YAU, JEFFREYAssociate ProfessorZACHARYPITKOWZACHARY PITKOW0.000000000000000.000000000000005607PITKOW, ZACHARYAdjunct Associate ProfessorD042501Chemicals & Drugs30370.959756Angiogenic Proteins2008-11-30NIHDUMAN, JOSEPH G2005-12-01Calcium dynamics in secretory granule-containing cellsF32DK0689822015-02-28NIHDUMAN, JOSEPH G2010-04-01Mechanism of Brain-Specific Angiogenesis Inhibitor 1 (BAI1) in Neural DevelopmentK01MH0861192022-07-31NIHDUMAN, JOSEPH G2017-09-01(PQ9) Directed and unbiased studies of synaptic injuries as sequelae of radiotherapy: mapping, sex-dependence, and reversalR01CA219667Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorDepartment of NeuroscienceDepartment of PediatricsDepartment of Molecular & Human GeneticsMolecular & Human GeneticsNeurosciencePediatrics-NeurologyBaylor College of MedicineKIMBERLEYTOLIASKIMBERLEY TOLIAS0.000000000000000.000000000000001061TOLIAS, KIMBERLEYProfessorAuthorship 1054431J. DAVIDDICKMANJ. DAVID DICKMAN0.000000000000000.000000000000001934DICKMAN, J. DAVIDProfessorHUDAZOGHBIHUDA ZOGHBI29.71010310000000-95.397396100000002830ZOGHBI, HUDADistinguished Service ProfessorHUGOBELLENHUGO BELLEN29.71010310000000-95.397396100000003292BELLEN, HUGODistinguished Service Professor2.192710.00507335167research areas4.52510.042639213coauthor of32.90393.7709360similar to1125selected publicationsPAULPFAFFINGERPAUL PFAFFINGER0.000000000000000.000000000000003336PFAFFINGER, PAULProfessorAuthorship 954610131461398Duman JG, Mulherkar S, Tu YK, Erikson KC, Tzeng CP, Mavratsas VC, Ho TS, Tolias KFeLifeThe adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest. Elife. 2019 08 28; 8.Elife2019-08-28T00:00:002019The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest.true1ProfessorProfessortrue1Postdoc Fellows and AssociatesPostdoc Fellows and AssociatesRintuThomasRintu Thomas15066Thomas, RintuPostdoc Fellows and AssociatesAuthorship 961733231773021Grosshans DR, Duman JG, Gaber MW, Sawakuchi GInternational journal of particle therapyParticle Radiation Induced Neurotoxicity in the Central Nervous System. Int J Part Ther. 2018; 5(1):74-83.Int J Part Ther2018-09-21T00:00:002018Particle Radiation Induced Neurotoxicity in the Central Nervous System.71Postdoc Fellows and AssociatesPostDocSHELLYBUFFINGTONSHELLY BUFFINGTON0.000000000000000.000000000000005872BUFFINGTON, SHELLYAssistant Professortrue1ProfessorProfessorAuthorship 993892532642710Zhang D, Zhou W, Lam TT, Li Y, Duman JG, Dougherty PM, Grosshans DRNeuro-oncology advancesCranial irradiation induces axon initial segment dysfunction and neuronal injury in the prefrontal cortex and impairs hippocampal coupling. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa058.Neurooncol Adv2020-05-11T00:00:002020Cranial irradiation induces axon initial segment dysfunction and neuronal injury in the prefrontal cortex and impairs hippocampal coupling.http://flypush.imgen.bcm.tmc.eduBellen Lab WebsiteAuthorship 10070141033328293Cheng J, Scala F, Blanco FA, Niu S, Firozi K, Keehan L, Mulherkar S, Froudarakis E, Li L, Duman JG, Jiang X, Tolias KFThe Journal of neuroscience : the official journal of the Society for NeuroscienceThe Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions. J Neurosci. 2021 02 10; 41(6):1191-1206.J Neurosci2020-12-16T00:00:002020The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions.Authorship 1017787133955328Duman JG, Blanco FA, Cronkite CA, Ru Q, Erikson KC, Mulherkar S, Saifullah AB, Firozi K, Tolias KFSmall GTPasesRac-maninoff and Rho-vel: The symphony of Rho-GTPase signaling at excitatory synapses. Small GTPases. 2022 01; 13(1):14-47.Small GTPases2021-05-06T00:00:002021Rac-maninoff and Rho-vel: The symphony of Rho-GTPase signaling at excitatory synapses.true1Associate ProfessorAssociate Professortrue1Distinguished Service ProfessorDistinguished Service Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1Adjunct Associate ProfessorAdjunct Associate ProfessorAuthorship 1090443938464175Grosshans D, Thomas R, Zhang D, Cronkite C, Thomas R, Singh S, Bronk L, Morales R, Duman JResearch squareSubcellular functions of tau mediates repair response and synaptic homeostasis in injury. Res Sq. 2024 Feb 29.Res Sq2024-02-29T00:00:002024Subcellular functions of tau mediates repair response and synaptic homeostasis in injury.true1Associate ProfessorAssociate Professortrue1InstructorInstructortrue1ProfessorProfessorAuthorship 2521Authorship 254731Authorship 422001Authorship 145866324960694Um K, Niu S, Duman JG, Cheng JX, Tu YK, Schwechter B, Liu F, Hiles L, Narayanan AS, Ash RT, Mulherkar S, Alpadi K, Smirnakis SM, Tolias KFDevelopmental cellDynamic control of excitatory synapse development by a Rac1 GEF/GAP regulatory complex. Dev Cell. 2014 Jun 23; 29(6):701-15.Dev Cell2014-06-23T00:00:002014Dynamic control of excitatory synapse development by a Rac1 GEF/GAP regulatory complex.Authorship 1548548