ANGSHUMOYROYANGSHUMOY ROY0.000000000000000.000000000000004422ROY, ANGSHUMOYAssociate Professorplugins:TwitterTwitterprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:orcidIdORCID idvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 81158425360585Peters TL, Kumar V, Polikepahad S, Lin FY, Sarabia SF, Liang Y, Wang WL, Lazar AJ, Doddapaneni H, Chao H, Muzny DM, Wheeler DA, Okcu MF, Plon SE, Hicks MJ, L?pez-Terrada D, Parsons DW, Roy AModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncBCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children. Mod Pathol. 2015 Apr; 28(4):575-86.Mod Pathol2014-10-31T00:00:002014BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children.Authorship 1069631Authorship 15871017Gynecological Oncology & Reproductive MedicineLeukemiaSurgical OncologyMD AndersonHAGOP MKANTARJIANHAGOP M KANTARJIAN8501KANTARJIAN, HAGOP MProfessorJEAN NICOLASVAUTHEYJEAN NICOLAS VAUTHEY8766VAUTHEY, JEAN NICOLASProfessorANIL KSOODANIL K SOOD9048SOOD, ANIL KProfessorAuthorship 462824Authorship 506043Authorship 781132Authorship 799733Authorship 2814512Authorship 2814522Authorship 28145310Authorship 2814541Authorship 2814551Authorship 281456226822237Parsons DW, Roy A, Yang Y, Wang T, Scollon S, Bergstrom K, Kerstein RA, Gutierrez S, Petersen AK, Bavle A, Lin FY, L?pez-Terrada DH, Monzon FA, Hicks MJ, Eldin KW, Quintanilla NM, Adesina AM, Mohila CA, Whitehead W, Jea A, Vasudevan SA, Nuchtern JG, Ramamurthy U, McGuire AL, Hilsenbeck SG, Reid JG, Muzny DM, Wheeler DA, Berg SL, Chintagumpala MM, Eng CM, Gibbs RA, Plon SEJAMA oncologyDiagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors. JAMA Oncol. 2016 May 01; 2(5):616-624.JAMA Oncol2016-05-01T00:00:002016Diagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors.26835391Schady DA, Roy A, Finegold MJTranslational pediatricsLiver tumors in children with metabolic disorders. Transl Pediatr. 2015 Oct; 4(4):290-303.Transl Pediatr2015-10-01T00:00:002015Liver tumors in children with metabolic disorders.26366474Ballester LY, Sarabia SF, Sayeed H, Patel N, Baalwa J, Athanassaki I, Hernandez JA, Fang E, Quintanilla NM, Roy A, L?pez-Terrada DHPediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology SocietyIntegrating Molecular Testing in the Diagnosis and Management of Children with Thyroid Lesions. Pediatr Dev Pathol. 2016 Mar-Apr; 19(2):94-100.Pediatr Dev Pathol2015-09-14T00:00:002015Integrating Molecular Testing in the Diagnosis and Management of Children with Thyroid Lesions.26355764Wiszniewska J, Roy A, Masand RPThe American Journal of dermatopathologyMyxoid Dermatofibrosarcoma Protuberans of the Vulva: Case Report of a Rare Variant in an Unusual Location, With Unusual Morphologic and Immunohistochemical Features. Am J Dermatopathol. 2016 Mar; 38(3):226-30.Am J Dermatopathol2016-03-01T00:00:002016Myxoid Dermatofibrosarcoma Protuberans of the Vulva: Case Report of a Rare Variant in an Unusual Location, With Unusual Morphologic and Immunohistochemical Features.26839229Roy A, Finegold MJSurgical pathology clinicsBiopsy Diagnosis of Inherited Liver Disease. Surg Pathol Clin. 2010 Sep; 3(3):743-68.Surg Pathol Clin2010-10-20T00:00:002010Biopsy Diagnosis of Inherited Liver Disease.16820665Sen K, Roy AIndian pediatricsManagement of neonatal purpura fulminans with severe protein C deficiency. Indian Pediatr. 2006 Jun; 43(6):542-5.Indian Pediatr2006-06-01T00:00:002006Management of neonatal purpura fulminans with severe protein C deficiency.Authorship 300641126573325Roy A, Kumar V, Zorman B, Fang E, Haines KM, Doddapaneni H, Hampton OA, White S, Bavle AA, Patel NR, Eldin KW, John Hicks M, Rakheja D, Leavey PJ, Skapek SX, Amatruda JF, Nuchtern JG, Chintagumpala MM, Wheeler DA, Plon SE, Sumazin P, Parsons DWNature communicationsRecurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney. Nat Commun. 2015 Nov 17; 6:8891.Nat Commun2015-11-17T00:00:002015Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney.74Professor21Chair14Associate Professor78Professor Emeritus17047026Yatsenko AN, Roy A, Chen R, Ma L, Murthy LJ, Yan W, Lamb DJ, Matzuk MMHuman molecular geneticsNon-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization. Hum Mol Genet. 2006 Dec 01; 15(23):3411-9.Hum Mol Genet2006-10-17T00:00:002006Non-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization.17080191Roy A, Lin YN, Matzuk MMThe Journal of clinical investigationShaping the sperm head: an ER enzyme leaves its mark. J Clin Invest. 2006 Nov; 116(11):2860-3.J Clin Invest2006-11-01T00:00:002006Shaping the sperm head: an ER enzyme leaves its mark.17244819Roy A, Lin YN, Agno JE, DeMayo FJ, Matzuk MMFASEB journal : official publication of the Federation of American Societies for Experimental BiologyAbsence of tektin 4 causes asthenozoospermia and subfertility in male mice. FASEB J. 2007 Apr; 21(4):1013-25.FASEB J2007-01-23T00:00:002007Absence of tektin 4 causes asthenozoospermia and subfertility in male mice.Authorship 3269881527626068Lin FY, Bergstrom K, Person R, Bavle A, Ballester LY, Scollon S, Raesz-Martinez R, Jea A, Birchansky S, Wheeler DA, Berg SL, Chintagumpala MM, Adesina AM, Eng C, Roy A, Plon SE, Parsons DWCold Spring Harbor molecular case studiesIntegrated tumor and germline whole-exome sequencing identifies mutations in MAPK and PI3K pathway genes in an adolescent with rosette-forming glioneuronal tumor of the fourth ventricle. Cold Spring Harb Mol Case Stud. 2016 Sep; 2(5):a001057.Cold Spring Harb Mol Case Stud2016-09-01T00:00:002016Integrated tumor and germline whole-exome sequencing identifies mutations in MAPK and PI3K pathway genes in an adolescent with rosette-forming glioneuronal tumor of the fourth ventricle.18951373Roy A, Lin YN, Agno JE, DeMayo FJ, Matzuk MMMolecular reproduction and developmentTektin 3 is required for progressive sperm motility in mice. Mol Reprod Dev. 2009 May; 76(5):453-9.Mol Reprod Dev2009-05-01T00:00:002009Tektin 3 is required for progressive sperm motility in mice.19730684Ma L, Buchold GM, Greenbaum MP, Roy A, Burns KH, Zhu H, Han DY, Harris RA, Coarfa C, Gunaratne PH, Yan W, Matzuk MMPLoS geneticsGASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet. 2009 Sep; 5(9):e1000635.PLoS Genet2009-09-04T00:00:002009GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline.1102 BATESHouston, 77030TX27729324Chakraborty R, Burke TM, Hampton OA, Zinn DJ, Lim KP, Abhyankar H, Scull B, Kumar V, Kakkar N, Wheeler DA, Roy A, Poulikakos PI, Merad M, McClain KL, Parsons DW, Allen CEBloodAlternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis. Blood. 2016 11 24; 128(21):2533-2537.Blood2016-10-11T00:00:002016Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis.Authorship 32845412Authorship 3285101127748010Potter SL, Venkatramani R, Wenderfer S, Graham BH, Vasudevan SA, Sher A, Wu H, Wheeler DA, Yang Y, Eng CM, Gibbs RA, Roy A, Plon SE, Parsons DWPediatric blood & cancerRenal cell carcinoma harboring somatic TSC2 mutations in a child with methylmalonic acidemia. Pediatr Blood Cancer. 2017 05; 64(5).Pediatr Blood Cancer2016-10-17T00:00:002016Renal cell carcinoma harboring somatic TSC2 mutations in a child with methylmalonic acidemia.23129109Franzblau EB, Punzalan RC, Friedman KD, Roy A, Bilen O, Flood VHPediatric blood & cancerUse of purified fibrinogen concentrate for dysfibrinogenemia and importance of laboratory fibrinogen activity measurement. Pediatr Blood Cancer. 2013 Mar; 60(3):500-2.Pediatr Blood Cancer2012-11-05T00:00:002012Use of purified fibrinogen concentrate for dysfibrinogenemia and importance of laboratory fibrinogen activity measurement.16452715Roy A, Matzuk MMReproduction (Cambridge, England)Deconstructing mammalian reproduction: using knockouts to define fertility pathways. Reproduction. 2006 Feb; 131(2):207-19.Reproduction2006-02-01T00:00:002006Deconstructing mammalian reproduction: using knockouts to define fertility pathways.Authorship 513200327814769Ritter DI, Roychowdhury S, Roy A, Rao S, Landrum MJ, Sonkin D, Shekar M, Davis CF, Hart RK, Micheel C, Weaver M, Van Allen EM, Parsons DW, McLeod HL, Watson MS, Plon SE, Kulkarni S, Madhavan S, ClinGen Somatic Cancer Working GroupGenome medicineSomatic cancer variant curation and harmonization through consensus minimum variant level data. Genome Med. 2016 11 04; 8(1):117.Genome Med2016-11-04T00:00:002016Somatic cancer variant curation and harmonization through consensus minimum variant level data.17664285Lin YN, Roy A, Yan W, Burns KH, Matzuk MMMolecular and cellular biologyLoss of zona pellucida binding proteins in the acrosomal matrix disrupts acrosome biogenesis and sperm morphogenesis. Mol Cell Biol. 2007 Oct; 27(19):6794-805.Mol Cell Biol2007-07-30T00:00:002007Loss of zona pellucida binding proteins in the acrosomal matrix disrupts acrosome biogenesis and sperm morphogenesis.17897580Roy A, Matzuk MMReproduction, fertility, and developmentSociety for Reproductive Biology Founders' Lecture 2007. Insights into germ cell biology: from the bench to the clinic. Reprod Fertil Dev. 2007; 19(7):783-91.Reprod Fertil Dev2007-01-01T00:00:002007Society for Reproductive Biology Founders' Lecture 2007. Insights into germ cell biology: from the bench to the clinic.21164297Mari?o-Enr?quez A, Wang WL, Roy A, Lopez-Terrada D, Lazar AJ, Fletcher CD, Coffin CM, Hornick JLThe American journal of surgical pathologyEpithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK. Am J Surg Pathol. 2011 Jan; 35(1):135-44.Am J Surg Pathol2011-01-01T00:00:002011Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK.21478040Hanchard NA, Shchelochkov OA, Roy A, Wiszniewska J, Wang J, Popek EJ, Karpen S, Wong LJ, Scaglia FMolecular genetics and metabolismDeoxyguanosine kinase deficiency presenting as neonatal hemochromatosis. Mol Genet Metab. 2011 Jul; 103(3):262-7.Mol Genet Metab2011-03-11T00:00:002011Deoxyguanosine kinase deficiency presenting as neonatal hemochromatosis.21055693Roy A, Finegold MJClinics in liver diseaseHepatic neoplasia and metabolic diseases in children. Clin Liver Dis. 2010 Nov; 14(4):731-46.Clin Liver Dis2010-11-01T00:00:002010Hepatic neoplasia and metabolic diseases in children.Authorship 7566631128219109Ballester LY, Cantu MD, Lim KPH, Sarabia SF, Ferguson LS, Renee Webb C, Allen CE, McClain KL, Mohila CA, Punia JN, Roy A, L?pez-Terrada DH, John Hicks M, Fisher KEHematological oncologyThe use of BRAF V600E mutation-specific immunohistochemistry in pediatric Langerhans cell histiocytosis. Hematol Oncol. 2018 Feb; 36(1):307-315.Hematol Oncol2017-02-20T00:00:002017The use of BRAF V600E mutation-specific immunohistochemistry in pediatric Langerhans cell histiocytosis.21911476Yatsenko AN, O'Neil DS, Roy A, Arias-Mendoza PA, Chen R, Murthy LJ, Lamb DJ, Matzuk MMMolecular human reproductionAssociation of mutations in the zona pellucida binding protein 1 (ZPBP1) gene with abnormal sperm head morphology in infertile men. Mol Hum Reprod. 2012 Jan; 18(1):14-21.Mol Hum Reprod2011-09-12T00:00:002011Association of mutations in the zona pellucida binding protein 1 (ZPBP1) gene with abnormal sperm head morphology in infertile men.Authorship 873121428643791Charville GW, Wang WL, Ingram DR, Roy A, Thomas D, Patel RM, Hornick JL, van de Rijn M, Lazar AJModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncEWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma. Mod Pathol. 2017 09; 30(9):1312-1320.Mod Pathol2017-06-23T00:00:002017EWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma.Authorship 876251928752842Patel NR, Chrisinger JSA, Demicco EG, Sarabia SF, Reuther J, Kumar E, Oliveira AM, Billings SD, Bov?e JVMG, Roy A, Lazar AJ, Lopez-Terrada DH, Wang WLModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncUSP6 activation in nodular fasciitis by promoter-swapping gene fusions. Mod Pathol. 2017 11; 30(11):1577-1588.Mod Pathol2017-07-28T00:00:002017USP6 activation in nodular fasciitis by promoter-swapping gene fusions.14735490Roy A, Yan W, Burns KH, Matzuk MMMolecular reproduction and developmentTektin3 encodes an evolutionarily conserved putative testicular microtubules-related protein expressed preferentially in male germ cells. Mol Reprod Dev. 2004 Mar; 67(3):295-302.Mol Reprod Dev2004-03-01T00:00:002004Tektin3 encodes an evolutionarily conserved putative testicular microtubules-related protein expressed preferentially in male germ cells.21610684Roy A, Matzuk MMNature reviews. EndocrinologyReproductive tract function and dysfunction in women. Nat Rev Endocrinol. 2011 May 24; 7(9):517-25.Nat Rev Endocrinol2011-05-24T00:00:002011Reproductive tract function and dysfunction in women.22183980Chavan RS, Patel KU, Roy A, Thompson PA, Chintagumpala M, Goss JA, Nuchtern JG, Finegold MJ, Parsons DW, L?pez-Terrada DHPediatric blood & cancerMutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma. Pediatr Blood Cancer. 2012 Jun; 58(6):1006-7.Pediatr Blood Cancer2011-12-19T00:00:002011Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.22305237Magoulas PL, El-Hattab AW, Roy A, Bali DS, Finegold MJ, Craigen WJHuman pathologyDiffuse reticuloendothelial system involvement in type IV glycogen storage disease with a novel GBE1 mutation: a case report and review. Hum Pathol. 2012 Jun; 43(6):943-51.Hum Pathol2012-02-02T00:00:002012Diffuse reticuloendothelial system involvement in type IV glycogen storage disease with a novel GBE1 mutation: a case report and review.Authorship 882079229691299Laetsch TW, Roy A, Xu L, Black JO, Coffin CM, Chi YY, Tian J, Spunt SL, Hawkins DS, Bridge JA, Parsons DW, Skapek SXClinical cancer research : an official journal of the American Association for Cancer ResearchUndifferentiated Sarcomas in Children Harbor Clinically Relevant Oncogenic Fusions and Gene Copy-Number Alterations: A Report from the Children's Oncology Group. Clin Cancer Res. 2018 08 15; 24(16):3888-3897.Clin Cancer Res2018-04-24T00:00:002018Undifferentiated Sarcomas in Children Harbor Clinically Relevant Oncogenic Fusions and Gene Copy-Number Alterations: A Report from the Children's Oncology Group.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorD015514Chemicals & Drugs2977550.663698Oncogene Proteins, Fusiontrue1Associate ProfessorAssociate ProfessorD043244Chemicals & Drugs1011820.89461Ribonuclease IIID008868Chemicals & Drugs21410.969529Microtubule ProteinsD018310Disorders19190.97983Sertoli-Leydig Cell TumorD020917Chemicals & Drugs30350.971925Receptor, trkAAuthorship 9149615Authorship 9293744Authorship 9316524Authorship 9400101129218886Madhavan S, Ritter D, Micheel C, Rao S, Roy A, Sonkin D, Mccoy M, Griffith M, Griffith OL, Mcgarvey P, Kulkarni SPacific Symposium on Biocomputing. Pacific Symposium on BiocomputingClinGen Cancer Somatic Working Group - standardizing and democratizing access to cancer molecular diagnostic data to drive translational research. Pac Symp Biocomput. 2018; 23:247-258.Pac Symp Biocomput2018-01-01T00:00:002018ClinGen Cancer Somatic Working Group - standardizing and democratizing access to cancer molecular diagnostic data to drive translational research.30275002David MP, Venkatramani R, Lopez-Terrada DH, Roy A, Patil N, Fisher KECold Spring Harbor molecular case studiesMultimodal molecular analysis of an atypical small cell carcinoma of the ovary, hypercalcemic type. Cold Spring Harb Mol Case Stud. 2018 10; 4(5).Cold Spring Harb Mol Case Stud2018-10-01T00:00:002018Multimodal molecular analysis of an atypical small cell carcinoma of the ovary, hypercalcemic type.29985454Charville GW, Wang WL, Ingram DR, Roy A, Thomas D, Patel RM, Hornick JL, van de Rijn M, Lazar AJModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncPAX7 expression in sarcomas bearing the EWSR1-NFATC2 translocation. Mod Pathol. 2019 01; 32(1):154-156.Mod Pathol2018-07-09T00:00:002018PAX7 expression in sarcomas bearing the EWSR1-NFATC2 translocation.30311370Danos AM, Ritter DI, Wagner AH, Krysiak K, Sonkin D, Micheel C, McCoy M, Rao S, Raca G, Boca SM, Roy A, Barnell EK, McMichael JF, Kiwala S, Coffman AC, Kujan L, Kulkarni S, Griffith M, Madhavan S, Griffith OL, Clinical Genome Resource Somatic Working Group and Clinical Interpretation of Variants in Cancer teaHuman mutationAdapting crowdsourced clinical cancer curation in CIViC to the ClinGen minimum variant level data community-driven standards. Hum Mutat. 2018 11; 39(11):1721-1732.Hum Mutat2018-11-01T00:00:002018Adapting crowdsourced clinical cancer curation in CIViC to the ClinGen minimum variant level data community-driven standards.Department of PediatricsDepartment of Molecular & Human GeneticsDepartment of Pathology & ImmunologyMolecular & Human GeneticsPathologyPediatrics-OncologyBaylor College of MedicineDONALDPARSONSDONALD PARSONS0.000000000000000.000000000000001458PARSONS, DONALD0000-0002-8775-3501ProfessorCHRISTIEFINCHCHRISTIE FINCH0.000000000000000.000000000000002005FINCH, CHRISTIEProfessorDOLORESLOPEZ-TERRADADOLORES LOPEZ-TERRADA0.000000000000000.000000000000002067LOPEZ-TERRADA, DOLORESProfessorMARTINMATZUKMARTIN MATZUK0.000000000000000.000000000000001976MATZUK, MARTINProfessorJAMESLUPSKIJAMES LUPSKI29.71073630000000-95.396604500000003140LUPSKI, JAMESProfessorGRAEMEMARDONGRAEME MARDON0.000000000000000.000000000000003439MARDON, GRAEMEProfessor1.093890.00548638343research areas3.075420.022785989coauthor of38.6749.9814960similar to1171selected publicationsDEBORAHSCHADYDEBORAH SCHADY0.000000000000000.000000000000001794SCHADY, DEBORAHAssociate ProfessorJAMESVERSALOVICJAMES VERSALOVIC0.000000000000000.000000000000003197VERSALOVIC, JAMESProfessorSHARONPLONSHARON PLON0.000000000000000.000000000000003410PLON, SHARON0000-0002-9626-0936ProfessorEDWINAPOPEKEDWINA POPEK0.000000000000000.000000000000003411POPEK, EDWINAProfessor EmeritusAuthorship 944342730977242Haines K, Sarabia SF, Alvarez KR, Tomlinson G, Vasudevan SA, Heczey AA, Roy A, Finegold MJ, Parsons DW, Plon SE, L?pez-Terrada DPediatric blood & cancerCharacterization of pediatric hepatocellular carcinoma reveals genomic heterogeneity and diverse signaling pathway activation. Pediatr Blood Cancer. 2019 07; 66(7):e27745.Pediatr Blood Cancer2019-04-11T00:00:002019Characterization of pediatric hepatocellular carcinoma reveals genomic heterogeneity and diverse signaling pathway activation.Authorship 1064341Authorship 951281631250550Hashmi SK, Punia JN, Marcogliese AN, Gaikwad AS, Fisher KE, Roy A, Rao P, Lopez-Terrada DH, Ringrose J, Loh ML, Niemeyer CM, Rau REPediatric blood & cancerSustained remission with azacitidine monotherapy and an aberrant precursor B-lymphoblast population in juvenile myelomonocytic leukemia. Pediatr Blood Cancer. 2019 10; 66(10):e27905.Pediatr Blood Cancer2019-06-28T00:00:002019Sustained remission with azacitidine monotherapy and an aberrant precursor B-lymphoblast population in juvenile myelomonocytic leukemia.Authorship 952526331339226Whittle SB, Hicks MJ, Roy A, Vasudevan SA, Reddy K, Venkatramani RPediatric blood & cancerCongenital spindle cell rhabdomyosarcoma. Pediatr Blood Cancer. 2019 11; 66(11):e27935.Pediatr Blood Cancer2019-07-24T00:00:002019Congenital spindle cell rhabdomyosarcoma.Authorship 1079651Authorship 9573971231624068Lindsay H, Scollon S, Reuther J, Voicu H, Rednam SP, Lin FY, Fisher KE, Chintagumpala M, Adesina AM, Parsons DW, Plon SE, Roy ACold Spring Harbor molecular case studiesGermline POLE mutation in a child with hypermutated medulloblastoma and features of constitutional mismatch repair deficiency. Cold Spring Harb Mol Case Stud. 2019 10; 5(5).Cold Spring Harb Mol Case Stud2019-10-23T00:00:002019Germline POLE mutation in a child with hypermutated medulloblastoma and features of constitutional mismatch repair deficiency.Authorship 957760431645346Hassan M, Butler E, Wilson R, Roy A, Zheng Y, Liem P, Rakheja D, Pavlick D, Young LL, Rosenzweig M, Erlich R, Ali SM, Leavey PJ, Parsons DW, Skapek SX, Laetsch TWCold Spring Harbor molecular case studiesNovel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib. Cold Spring Harb Mol Case Stud. 2019 10; 5(5).Cold Spring Harb Mol Case Stud2019-10-23T00:00:002019Novel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib.true1ProfessorProfessortrue1ProfessorProfessor2Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate ProfessorAuthorship 960485731682773Zhou T, Bloomquist MS, Ferguson LS, Reuther J, Marcogliese AN, Elghetany MT, Roy A, Rao PH, Lopez-Terrada DH, Redell MS, Punia JN, Curry CV, Fisher KEPediatric hematology and oncologyPediatric myeloid sarcoma: a single institution clinicopathologic and molecular analysis. Pediatr Hematol Oncol. 2020 Feb; 37(1):76-89.Pediatr Hematol Oncol2019-11-04T00:00:002019Pediatric myeloid sarcoma: a single institution clinicopathologic and molecular analysis.Authorship 974698531876361Han H, Bertrand KC, Patel KR, Fisher KE, Roy A, Muscal JA, Venkatramani RPediatric blood & cancerBCOR-CCNB3 fusion-positive clear cell sarcoma of the kidney. Pediatr Blood Cancer. 2020 04; 67(4):e28151.Pediatr Blood Cancer2019-12-26T00:00:002019BCOR-CCNB3 fusion-positive clear cell sarcoma of the kidney.true1ProfessorProfessorAuthorship 996841932782782Dupuis M, Shen Y, Curcio C, Meis JM, Wang WL, Amini B, Rhines L, Reuther J, Roy A, Fisher KE, Conley AP, Andrew Livingston JClinical sarcoma researchSuccessful treatment of lipofibromatosis-like neural tumor of the lumbar spine with an NTRK-fusion inhibitor. Clin Sarcoma Res. 2020; 10:14.Clin Sarcoma Res2020-08-06T00:00:002020Successful treatment of lipofibromatosis-like neural tumor of the lumbar spine with an NTRK-fusion inhibitor.Authorship 9974236Authorship 997543332815783Amra N, Zarate LV, Punia JN, Mahajan P, Stevens AM, Roy A, Curry CV, Cortes-Santiago N, Fisher KEPediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology SocietyMediastinal Germ Cell Tumor and Acute Megakaryoblastic Leukemia With Co-occurring KRAS Mutation and Complex Cytogenetics. Pediatr Dev Pathol. 2020 Nov-Dec; 23(6):461-466.Pediatr Dev Pathol2020-08-20T00:00:002020Mediastinal Germ Cell Tumor and Acute Megakaryoblastic Leukemia With Co-occurring KRAS Mutation and Complex Cytogenetics.32821910Chandramohan R, Kakkar N, Roy A, Parsons DWBioinformatics (Oxford, England)reconCNV: interactive visualization of copy number data from high-throughput sequencing. Bioinformatics. 2021 05 23; 37(8):1164-1167.Bioinformatics2021-05-23T00:00:002021reconCNV: interactive visualization of copy number data from high-throughput sequencing.Authorship 99800411Authorship 998166432843649Manica M, Kim HR, Mathis R, Chouvarine P, Rutishauser D, De Vargas Roditi L, Szalai B, Wagner U, Oehl K, Saba K, Pati A, Saez-Rodriguez J, Roy A, Parsons DW, Wild PJ, Mart?nez MR, Sumazin PNPJ systems biology and applicationsInferring clonal composition from multiple tumor biopsies. NPJ Syst Biol Appl. 2020 08 25; 6(1):27.NPJ Syst Biol Appl2020-08-25T00:00:002020Inferring clonal composition from multiple tumor biopsies.32856501Chang RJ, Reuther J, Gandhi I, Roy A, Jain S, Masand RPInternational journal of surgical pathologySex Cord Tumor With Annular Tubules-Like Histologic Pattern in Adult Granulosa Cell Tumor: Case Report of a Hitherto Unreported Morphologic Variant. Int J Surg Pathol. 2021 Jun; 29(4):433-437.Int J Surg Pathol2020-08-28T00:00:002020Sex Cord Tumor With Annular Tubules-Like Histologic Pattern in Adult Granulosa Cell Tumor: Case Report of a Hitherto Unreported Morphologic Variant.http://www.texaschildrens.org/departments/cancer-genetics-clinic/our-teamTexas Children's Cancer Genetics Clinichttps://www.bcm.edu/people-search/sharon-plon-28865My Research SitesplonAuthorship 10008771833009870Potter SL, Reuther J, Chandramohan R, Gandhi I, Hollingsworth F, Sayeed H, Voicu H, Kakkar N, Baksi KS, Sarabia SF, Lopez ME, Chelius DC, Athanassaki ID, Mahajan P, Venkatramani R, Quintanilla NM, Lopez-Terrada DH, Roy A, Parsons DWPediatric blood & cancerIntegrated DNA and RNA sequencing reveals targetable alterations in metastatic pediatric papillary thyroid carcinoma. Pediatr Blood Cancer. 2021 01; 68(1):e28741.Pediatr Blood Cancer2020-10-03T00:00:002020Integrated DNA and RNA sequencing reveals targetable alterations in metastatic pediatric papillary thyroid carcinoma.Authorship 1183541Authorship 115521Authorship 10202751534086347Ting MA, Reuther J, Chandramohan R, Voicu H, Gandhi I, Liu M, Cortes-Santiago N, Foster JH, Hicks J, Nuchtern J, Scollon S, Plon SE, Chintagumpala M, Rainusso N, Roy A, Parsons DWThe Journal of pathologyGenomic analysis and preclinical xenograft model development identify potential therapeutic targets for MYOD1-mutant soft-tissue sarcoma of childhood. J Pathol. 2021 09; 255(1):52-61.J Pathol2021-07-07T00:00:002021Genomic analysis and preclinical xenograft model development identify potential therapeutic targets for MYOD1-mutant soft-tissue sarcoma of childhood.33093355Carter-Febres M, Schneller N, Fair D, Solomon D, Perry A, Roy A, Linscott L, Alashari M, Kestle JR, Bruggers CSJournal of pediatric hematology/oncologyAdjuvant Maintenance Larotrectinib Therapy in 2 Children With NTRK Fusion-positive High-grade Cancers. J Pediatr Hematol Oncol. 2021 Oct 01; 43(7):e987-e990.J Pediatr Hematol Oncol2021-10-01T00:00:002021Adjuvant Maintenance Larotrectinib Therapy in 2 Children With NTRK Fusion-positive High-grade Cancers.Authorship 10291676Authorship 1029205534486543Kelly GA, Venkatramani R, Quintanilla NM, Chelius DC, Roy A, Mahajan PJournal of pediatric hematology/oncologySecretory Carcinoma of the Salivary Gland: A Rarity in Children. J Pediatr Hematol Oncol. 2022 05 01; 44(4):167-172.J Pediatr Hematol Oncol2021-09-06T00:00:002021Secretory Carcinoma of the Salivary Gland: A Rarity in Children.Authorship 10315421734651095Mangum R, Reuther J, Bertrand KC, Chandramohan R, Kukreja MK, Paulino AC, Muzny D, Hu J, Gibbs RA, Curry DJ, Malbari F, Chintagumpala MM, Adesina AM, Fisher KE, Mack SC, Plon SE, Roy A, Parsons DW, Lin FYJCO precision oncologyDurable Response to Larotrectinib in a Child With Histologic Diagnosis of Recurrent Disseminated Ependymoma Discovered to Harbor an NTRK2 Fusion: The Impact of Integrated Genomic Profiling. JCO Precis Oncol. 2021; 5.JCO Precis Oncol2021-07-28T00:00:002021Durable Response to Larotrectinib in a Child With Histologic Diagnosis of Recurrent Disseminated Ependymoma Discovered to Harbor an NTRK2 Fusion: The Impact of Integrated Genomic Profiling.Authorship 1032820434764425Wagner AH, Akkari Y, Li M, Roy A, Tsuchiya K, Raca GLeukemiaRecommendations for future extensions to the HGNC gene fusion nomenclature. Leukemia. 2021 12; 35(12):3611-3612.Leukemia2021-11-11T00:00:002021Recommendations for future extensions to the HGNC gene fusion nomenclature.Authorship 1035563434907337Wagner AH, Akkari Y, Li M, Roy A, Tsuchiya K, Raca GLeukemiaCorrection to: Recommendations for future extensions to the HGNC gene fusion nomenclature. Leukemia. 2022 Jan; 36(1):299-300.Leukemia2022-01-01T00:00:002022Correction to: Recommendations for future extensions to the HGNC gene fusion nomenclature.Authorship 10373041935026696Garcia A, Desrosiers L, Scollon S, Gruner S, Reuther J, Gandhi I, Patil N, Fuller MY, Dai H, Muzny D, Gibbs RA, Bercaw-Pratt JL, Rao SL, Rainusso N, Fisher KE, Lin FY, Plon SE, Parsons DW, Roy ACancer geneticsDistinct somatic DICER1 hotspot mutations in three metachronous ovarian Sertoli-Leydig cell tumors in a patient with DICER1 syndrome. Cancer Genet. 2022 04; 262-263:53-56.Cancer Genet2022-01-05T00:00:002022Distinct somatic DICER1 hotspot mutations in three metachronous ovarian Sertoli-Leydig cell tumors in a patient with DICER1 syndrome.35451474Woodfield SE, Mistretta BJ, Patel RH, Ibarra AM, Fisher KE, Sarabia SF, Gandhi I, Reuther J, Starosolski Z, Badachhape A, Epps J, Zorman B, Shah AP, Larson SR, Srivastava RK, Shi Y, Espinoza AF, Govindu SR, Whitlock RS, Holloway K, Roy A, Sumazin P, Ghaghada KB, Lopez-Terrada D, Gunaratne PH, Vasudevan SABiology openHepT1-derived murine models of high-risk hepatoblastoma display vascular invasion, metastasis, and circulating tumor cells. Biol Open. 2022 09 15; 11(9).Biol Open2022-09-12T00:00:002022HepT1-derived murine models of high-risk hepatoblastoma display vascular invasion, metastasis, and circulating tumor cells.Authorship 10431321635487348Chandramohan R, Reuther J, Gandhi I, Voicu H, Alvarez KR, Plon SE, Lopez-Terrada DH, Fisher KE, Parsons DW, Roy AThe Journal of molecular diagnostics : JMDA Validation Framework for Somatic Copy Number Detection in Targeted Sequencing Panels. J Mol Diagn. 2022 07; 24(7):760-774.J Mol Diagn2022-04-26T00:00:002022A Validation Framework for Somatic Copy Number Detection in Targeted Sequencing Panels.35366592Saliba J, Church AJ, Rao S, Danos A, Furtado LV, Laetsch T, Zhang L, Nardi V, Lin WH, Ritter DI, Madhavan S, Li MM, Griffith OL, Griffith M, Raca G, Roy ACancer geneticsStandardized evidence-based approach for assessment of oncogenic and clinical significance of NTRK fusions. Cancer Genet. 2022 06; 264-265:50-59.Cancer Genet2022-03-16T00:00:002022Standardized evidence-based approach for assessment of oncogenic and clinical significance of NTRK fusions.Authorship 104430021Authorship 10447211035537005Whittle SB, Fetzko S, Roy A, Venkatramani RJournal of pediatric hematology/oncologySoft Tissue and Visceral Organ Sarcomas With BCOR Alterations. J Pediatr Hematol Oncol. 2022 07 01; 44(5):195-200.J Pediatr Hematol Oncol2022-05-04T00:00:002022Soft Tissue and Visceral Organ Sarcomas With BCOR Alterations.35577029Sumazin P, Peters TL, Sarabia SF, Kim HR, Urbicain M, Hollingsworth EF, Alvarez KR, Perez CR, Pozza A, Najaf Panah MJ, Epps JL, Scorsone K, Zorman B, Katzenstein H, O'Neill AF, Meyers R, Tiao G, Geller J, Ranganathan S, Rangaswami AA, Woodfield SE, Goss JA, Vasudevan SA, Heczey A, Roy A, Fisher KE, Alaggio R, Patel KR, Finegold MJ, L?pez-Terrada DHJournal of hepatologyHepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults. J Hepatol. 2022 10; 77(4):1026-1037.J Hepatol2022-05-14T00:00:002022Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults.Authorship 10457283Authorship 104606024Authorship 10479041735713195Scollon S, Eldomery MK, Reuther J, Lin FY, Potter SL, Desrosiers L, McClain KL, Smith V, Su JM, Venkatramani R, Hu J, Korchina V, Zarrin-Khameh N, Gibbs RA, Muzny DM, Eng C, Roy A, Parsons DW, Plon SEPediatric blood & cancerClinical and molecular features of pediatric cancer patients with Lynch syndrome. Pediatr Blood Cancer. 2022 11; 69(11):e29859.Pediatr Blood Cancer2022-06-30T00:00:002022Clinical and molecular features of pediatric cancer patients with Lynch syndrome.true1Associate ProfessorAssociate ProfessorAuthorship 10621061336346368Chen Wongworawat Y, Eskandari G, Gaikwad A, Marcogliese AN, Ferguson LS, Brackett J, Punia JN, Elghetany MT, Kulkarni R, Rao PH, Ringrose J, Lopez-Terrada DH, Roy A, Curry CV, Fisher KELeukemia & lymphomaFrequent detection of CBFA2T3::GLIS2 fusion and RAM-phenotype in pediatric non-Down syndrome acute megakaryoblastic leukemia: a possible novel relationship with aberrant cytoplasmic CD3 expression. Leuk Lymphoma. 2023 02; 64(2):462-467.Leuk Lymphoma2022-11-08T00:00:002022Frequent detection of CBFA2T3::GLIS2 fusion and RAM-phenotype in pediatric non-Down syndrome acute megakaryoblastic leukemia: a possible novel relationship with aberrant cytoplasmic CD3 expression.true1ProfessorProfessorAuthorship 13382337366551Mangum R, Reuther J, Sen Baksi K, Gandhi I, Zabriskie RC, Recinos A, Raesz-Martinez R, Lin FY, Potter SL, Sher AC, Kralik SF, Mohila CA, Chintagumpala MM, Muzny D, Hu J, Gibbs RA, Fisher KE, Bernini JC, Gill J, Griffin TC, Tomlinson GE, Vallance KL, Plon SE, Roy A, Parsons DWPediatric hematology and oncologyCirculating tumor DNA sequencing of pediatric solid and brain tumor patients: An institutional feasibility study. Pediatr Hematol Oncol. 2023; 40(8):719-738.Pediatr Hematol Oncol2023-06-27T00:00:002023Circulating tumor DNA sequencing of pediatric solid and brain tumor patients: An institutional feasibility study.Authorship 107257424https://www.texaschildrens.org/find-a-doctor/sharon-e-plon-md-phd-facmgTexas Children's Hospital Profiletrue1ProfessorProfessorAuthorship 10794727Authorship 1077802537625831Naik U, Shah M, Sandberg DI, Samant R, Roy A, Bhattacharjee MBAnnals of clinical and laboratory scienceHistopathologic "Evolution" in Pediatric Primary Intracranial High-Grade Sarcoma - a Key that Unlocked the Correct Diagnosis. Ann Clin Lab Sci. 2023 Jul; 53(4):661-666.Ann Clin Lab Sci2023-07-01T00:00:002023Histopathologic "Evolution" in Pediatric Primary Intracranial High-Grade Sarcoma - a Key that Unlocked the Correct Diagnosis.37535666Bridge JA, Halling KC, Moncur JT, Souers RJ, Hameed MR, Fernandes H, Roy A, Surrey L, Tafe LJ, Vasalos P, Lopez-Terrada DHArchives of pathology & laboratory medicineRNA Sequencing for Solid Tumor Fusion Gene Detection: Proficiency Testing Practice and Performance Comparison. Arch Pathol Lab Med. 2023 Aug 03.Arch Pathol Lab Med2023-08-03T00:00:002023RNA Sequencing for Solid Tumor Fusion Gene Detection: Proficiency Testing Practice and Performance Comparison.true1Professor EmeritusProfessor EmeritusAuthorship 10817731037852169Tsuchiya KD, Funke B, Hegde M, Santani A, Souers RJ, Szelinger S, Halley J, Zhao Q, Mot N, Roy A, Smith VL, Zhang BM, Voelkerding K, Moyer AMArchives of pathology & laboratory medicineImplementation, Evolution, and Laboratory Performance of Methods-Based Proficiency Testing for Next-Generation Sequencing Detection of Germline Sequence Variants. Arch Pathol Lab Med. 2023 Oct 18.Arch Pathol Lab Med2023-10-18T00:00:002023Implementation, Evolution, and Laboratory Performance of Methods-Based Proficiency Testing for Next-Generation Sequencing Detection of Germline Sequence Variants.Authorship 1084595637961416Hirschi OR, Felker SA, Rednam SP, Vallance KL, Parsons DW, Roy A, Cooper GM, Plon SEmedRxiv : the preprint server for health sciencesCombined Bioinformatic and Splicing Analysis of Likely Benign Intronic and Synonymous Variants Reveals Evidence for Pathogenicity. medRxiv. 2023 Nov 01.medRxiv2023-11-01T00:00:002023Combined Bioinformatic and Splicing Analysis of Likely Benign Intronic and Synonymous Variants Reveals Evidence for Pathogenicity.Authorship 180461true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 1396372Authorship 142372724561214Blanco EM, Curry CV, Lu XY, Sarabia SF, Redell MS, Lopez-Terrada DH, Roy ACancer geneticsCytogenetically cryptic and FISH-negative PML/RARA rearrangement in acute promyelocytic leukemia detected only by PCR: an exceedingly rare phenomenon. Cancer Genet. 2014 Jan-Feb; 207(1-2):48-9.Cancer Genet2014-01-16T00:00:002014Cytogenetically cryptic and FISH-negative PML/RARA rearrangement in acute promyelocytic leukemia detected only by PCR: an exceedingly rare phenomenon.Authorship 643331Authorship 149024224958819Parsons DW, Roy A, Plon SE, Roychowdhury S, Chinnaiyan AMJournal of clinical oncology : official journal of the American Society of Clinical OncologyClinical tumor sequencing: an incidental casualty of the American College of Medical Genetics and Genomics recommendations for reporting of incidental findings. J Clin Oncol. 2014 Jul 20; 32(21):2203-5.J Clin Oncol2014-06-23T00:00:002014Clinical tumor sequencing: an incidental casualty of the American College of Medical Genetics and Genomics recommendations for reporting of incidental findings.Authorship 771661Authorship 560652Authorship 802373KEVINFISHERKEVIN FISHER7942FISHER, KEVINAssociate Professor