HUGO BELLEN to Animals
This is a "connection" page, showing publications HUGO BELLEN has written about Animals.
Connection Strength
4.937
-
Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress. Nat Neurosci. 2024 Oct; 27(10):1918-1933.
Score: 0.052
-
Dominant missense variants in SREBF2 are associated with complex dermatological, neurological, and skeletal abnormalities. Genet Med. 2024 Sep; 26(9):101174.
Score: 0.051
-
Does glial lipid dysregulation alter sleep in Alzheimer's and Parkinson's disease? Trends Mol Med. 2024 Oct; 30(10):913-923.
Score: 0.051
-
Homozygous missense variants in YKT6 result in loss of function and are associated with developmental delay, with or without severe infantile liver disease and risk for hepatocellular carcinoma. Genet Med. 2024 Jul; 26(7):101125.
Score: 0.051
-
De novo variants in FRYL are associated with developmental delay, intellectual disability, and dysmorphic features. Am J Hum Genet. 2024 04 04; 111(4):742-760.
Score: 0.050
-
Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Proc Natl Acad Sci U S A. 2024 Feb 27; 121(9):e2322582121.
Score: 0.050
-
A defect in mitochondrial fatty acid synthesis impairs iron metabolism and causes elevated ceramide levels. Nat Metab. 2023 09; 5(9):1595-1614.
Score: 0.049
-
Integrating non-mammalian model organisms in the diagnosis of rare genetic diseases in humans. Nat Rev Genet. 2024 Jan; 25(1):46-60.
Score: 0.048
-
The Voltage-Gated Sodium Channel in Drosophila, Para, Localizes to Dendrites As Well As Axons in Mechanosensitive Chordotonal Neurons. eNeuro. 2023 Jun; 10(6).
Score: 0.048
-
Very-long-chain fatty acids induce glial-derived sphingosine-1-phosphate synthesis, secretion, and neuroinflammation. Cell Metab. 2023 05 02; 35(5):855-874.e5.
Score: 0.047
-
Bi-allelic variants in INTS11 are associated with a complex neurological disorder. Am J Hum Genet. 2023 05 04; 110(5):774-789.
Score: 0.047
-
Glia-neuron coupling via a bipartite sialylation pathway promotes neural transmission and stress tolerance in Drosophila. Elife. 2023 03 22; 12.
Score: 0.047
-
Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14). Elife. 2023 01 16; 12.
Score: 0.047
-
De novo variants in FRMD5 are associated with developmental delay, intellectual disability, ataxia, and abnormalities of eye movement. Am J Hum Genet. 2022 10 06; 109(10):1932-1943.
Score: 0.046
-
The recurrent de novo c.2011C>T missense variant in MTSS2 causes syndromic intellectual disability. Am J Hum Genet. 2022 10 06; 109(10):1923-1931.
Score: 0.045
-
Promoting validation and cross-phylogenetic integration in model organism research. Dis Model Mech. 2022 09 01; 15(9).
Score: 0.045
-
Novel dominant and recessive variants in human ROBO1 cause distinct neurodevelopmental defects through different mechanisms. Hum Mol Genet. 2022 08 23; 31(16):2751-2765.
Score: 0.045
-
Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia. Sci Adv. 2022 07 15; 8(28):eabn3326.
Score: 0.045
-
An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Elife. 2022 06 20; 11.
Score: 0.045
-
'Fly-ing' from rare to common neurodegenerative disease mechanisms. Trends Genet. 2022 09; 38(9):972-984.
Score: 0.044
-
Lord of the fruit flies: an interview with Hugo Bellen. Dis Model Mech. 2022 03 01; 15(3).
Score: 0.044
-
Low doses of the organic insecticide spinosad trigger lysosomal defects, elevated ROS, lipid dysregulation, and neurodegeneration in flies. Elife. 2022 02 22; 11.
Score: 0.044
-
Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling. Sci Adv. 2022 01 21; 8(3):eabl5613.
Score: 0.044
-
Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes. Proc Natl Acad Sci U S A. 2021 12 28; 118(52).
Score: 0.043
-
Model organism databases are in jeopardy. Development. 2021 10 01; 148(19).
Score: 0.043
-
Recent insights into the role of glia and oxidative stress in Alzheimer's disease gained from Drosophila. Curr Opin Neurobiol. 2022 02; 72:32-38.
Score: 0.042
-
Using Drosophila to drive the diagnosis and understand the mechanisms of rare human diseases. Development. 2020 09 28; 147(21).
Score: 0.040
-
Drosophila Voltage-Gated Sodium Channels Are Only Expressed in Active Neurons and Are Localized to Distal Axonal Initial Segment-like Domains. J Neurosci. 2020 10 14; 40(42):7999-8024.
Score: 0.040
-
Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms. Neuron. 2020 05 20; 106(4):589-606.e6.
Score: 0.038
-
The fruit fly at the interface of diagnosis and pathogenic mechanisms of rare and common human diseases. Hum Mol Genet. 2019 11 21; 28(R2):R207-R214.
Score: 0.037
-
Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly. Dev Cell. 2019 12 16; 51(6):713-729.e6.
Score: 0.037
-
An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. Elife. 2019 11 01; 8.
Score: 0.037
-
La CaSSA da Drosophila: A Versatile Expansion of the Tool Box. Neuron. 2019 10 23; 104(2):177-179.
Score: 0.037
-
VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway. Autophagy. 2019 07; 15(7):1214-1233.
Score: 0.036
-
Sphingolipids in the Pathogenesis of Parkinson's Disease and Parkinsonism. Trends Endocrinol Metab. 2019 02; 30(2):106-117.
Score: 0.035
-
An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila. Elife. 2018 08 09; 7.
Score: 0.034
-
Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to a-Synuclein Gain. Cell Metab. 2018 10 02; 28(4):605-618.e6.
Score: 0.034
-
Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms. Dev Cell. 2018 04 23; 45(2):226-244.e8.
Score: 0.034
-
A gene-specific T2A-GAL4 library for Drosophila. Elife. 2018 03 22; 7.
Score: 0.033
-
A kinase-dependent feedforward loop affects CREBB stability and long term memory formation. Elife. 2018 02 23; 7.
Score: 0.033
-
The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples Mitochondrial Metabolism to Synaptic Transmission. Cell Rep. 2017 12 26; 21(13):3794-3806.
Score: 0.033
-
Genetic strategies to tackle neurological diseases in fruit flies. Curr Opin Neurobiol. 2018 06; 50:24-32.
Score: 0.033
-
The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D. Cell Metab. 2017 Nov 07; 26(5):719-737.e6.
Score: 0.032
-
Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research. Genetics. 2017 09; 207(1):9-27.
Score: 0.032
-
Peroxisomal biogenesis is genetically and biochemically linked to carbohydrate metabolism in Drosophila and mouse. PLoS Genet. 2017 Jun; 13(6):e1006825.
Score: 0.032
-
Building dialogues between clinical and biomedical research through cross-species collaborations. Semin Cell Dev Biol. 2017 10; 70:49-57.
Score: 0.032
-
A cell cycle-independent, conditional gene inactivation strategy for differentially tagging wild-type and mutant cells. Elife. 2017 05 31; 6.
Score: 0.032
-
Loss of Nardilysin, a Mitochondrial Co-chaperone for a-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. Neuron. 2017 Jan 04; 93(1):115-131.
Score: 0.031
-
Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals. Elife. 2016 11 30; 5.
Score: 0.030
-
Amyotrophic Lateral Sclerosis Pathogenesis Converges on Defects in Protein Homeostasis Associated with TDP-43 Mislocalization and Proteasome-Mediated Degradation Overload. Curr Top Dev Biol. 2017; 121:111-171.
Score: 0.030
-
Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration. Elife. 2016 06 25; 5.
Score: 0.030
-
The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. Elife. 2016 06 22; 5.
Score: 0.030
-
Drosophila tools and assays for the study of human diseases. Dis Model Mech. 2016 Mar; 9(3):235-44.
Score: 0.029
-
WAC Regulates mTOR Activity by Acting as an Adaptor for the TTT and Pontin/Reptin Complexes. Dev Cell. 2016 Jan 25; 36(2):139-51.
Score: 0.029
-
Morgan's legacy: fruit flies and the functional annotation of conserved genes. Cell. 2015 Sep 24; 163(1):12-4.
Score: 0.028
-
Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress. PLoS Biol. 2015 Jul; 13(7):e1002197.
Score: 0.028
-
The retromer complex in development and disease. Development. 2015 Jul 15; 142(14):2392-6.
Score: 0.028
-
A genetic toolkit for tagging intronic MiMIC containing genes. Elife. 2015 Jun 23; 4.
Score: 0.028
-
A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila. Elife. 2015 Mar 31; 4.
Score: 0.027
-
Fruit flies in biomedical research. Genetics. 2015 Mar; 199(3):639-53.
Score: 0.027
-
Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration. Cell. 2015 Jan 15; 160(1-2):177-90.
Score: 0.027
-
Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production. Elife. 2014 Oct 14; 3.
Score: 0.026
-
Large-scale identification of chemically induced mutations in Drosophila melanogaster. Genome Res. 2014 Oct; 24(10):1707-18.
Score: 0.026
-
Survival of the fittest tools. Genetics. 2014 Oct; 198(2):427-8.
Score: 0.026
-
A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases. Cell. 2014 Sep 25; 159(1):200-214.
Score: 0.026
-
A mitocentric view of Parkinson's disease. Annu Rev Neurosci. 2014; 37:137-59.
Score: 0.026
-
The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration. PLoS Biol. 2014 Apr; 12(4):e1001847.
Score: 0.025
-
Shared mechanisms between Drosophila peripheral nervous system development and human neurodegenerative diseases. Curr Opin Neurobiol. 2014 Aug; 27:158-64.
Score: 0.025
-
Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster. Methods. 2014 Jun 15; 68(1):15-28.
Score: 0.025
-
Drosophila Tempura, a novel protein prenyltransferase a subunit, regulates notch signaling via Rab1 and Rab11. PLoS Biol. 2014 Jan; 12(1):e1001777.
Score: 0.025
-
Introduction to Notch signaling. Methods Mol Biol. 2014; 1187:1-14.
Score: 0.025
-
Preface. Notch signaling. Methods Mol Biol. 2014; 1187:v.
Score: 0.025
-
Rhodopsin homeostasis and retinal degeneration: lessons from the fly. Trends Neurosci. 2013 Nov; 36(11):652-60.
Score: 0.024
-
Drosophila EHBP1 regulates Scabrous secretion during Notch-mediated lateral inhibition. J Cell Sci. 2013 Aug 15; 126(Pt 16):3686-96.
Score: 0.024
-
The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit. J Cell Biol. 2013 Mar 18; 200(6):807-20.
Score: 0.024
-
Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells. PLoS Biol. 2012; 10(12):e1001438.
Score: 0.023
-
A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands. Science. 2012 Nov 30; 338(6111):1229-32.
Score: 0.023
-
Probing mechanisms that underlie human neurodegenerative diseases in Drosophila. Annu Rev Genet. 2012; 46:371-96.
Score: 0.023
-
dEHBP1 controls exocytosis and recycling of Delta during asymmetric divisions. J Cell Biol. 2012 Jan 09; 196(1):65-83.
Score: 0.022
-
Genome-wide manipulations of Drosophila melanogaster with transposons, Flp recombinase, and FC31 integrase. Methods Mol Biol. 2012; 859:203-28.
Score: 0.022
-
Genetic manipulation of genes and cells in the nervous system of the fruit fly. Neuron. 2011 Oct 20; 72(2):202-30.
Score: 0.021
-
MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes. Nat Methods. 2011 Sep; 8(9):737-43.
Score: 0.021
-
Rich regulates target specificity of photoreceptor cells and N-cadherin trafficking in the Drosophila visual system via Rab6. Neuron. 2011 Aug 11; 71(3):447-59.
Score: 0.021
-
The Drosophila gene disruption project: progress using transposons with distinctive site specificities. Genetics. 2011 Jul; 188(3):731-43.
Score: 0.021
-
The BMP signaling pathway at the Drosophila neuromuscular junction and its links to neurodegenerative diseases. Curr Opin Neurobiol. 2011 Feb; 21(1):182-8.
Score: 0.020
-
100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future. Nat Rev Neurosci. 2010 Jul; 11(7):514-22.
Score: 0.020
-
Endocytosis and intracellular trafficking of Notch and its ligands. Curr Top Dev Biol. 2010; 92:165-200.
Score: 0.019
-
Rab3 GTPase lands Bruchpilot. Neuron. 2009 Dec 10; 64(5):595-7.
Score: 0.019
-
Cell adhesion, the backbone of the synapse: "vertebrate" and "invertebrate" perspectives. Cold Spring Harb Perspect Biol. 2009 Oct; 1(4):a003079.
Score: 0.019
-
A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis. Cell. 2009 Sep 04; 138(5):947-60.
Score: 0.018
-
Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling. Neuron. 2009 Jul 30; 63(2):203-15.
Score: 0.018
-
The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy. J Cell Biol. 2009 Jun 29; 185(7):1181-94.
Score: 0.018
-
The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors. Nat Cell Biol. 2009 Jul; 11(7):815-24.
Score: 0.018
-
Sequoia regulates cell fate decisions in the external sensory organs of adult Drosophila. EMBO Rep. 2009 Jun; 10(6):636-41.
Score: 0.018
-
Importin 13 regulates neurotransmitter release at the Drosophila neuromuscular junction. J Neurosci. 2009 Apr 29; 29(17):5628-39.
Score: 0.018
-
A Notch updated. J Cell Biol. 2009 Mar 09; 184(5):621-9.
Score: 0.018
-
Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster. J Cell Biol. 2008 Sep 22; 182(6):1113-25.
Score: 0.017
-
The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors. Cell. 2008 Jun 13; 133(6):963-77.
Score: 0.017
-
straightjacket is required for the synaptic stabilization of cacophony, a voltage-gated calcium channel alpha1 subunit. J Cell Biol. 2008 Apr 07; 181(1):157-70.
Score: 0.017
-
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration. Nature. 2008 Apr 17; 452(7189):887-91.
Score: 0.017
-
Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling. Cell. 2008 Jan 25; 132(2):247-58.
Score: 0.017
-
FM 1-43 labeling of synaptic vesicle pools at the Drosophila neuromuscular junction. Methods Mol Biol. 2008; 440:349-69.
Score: 0.016
-
Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles. J Cell Biol. 2007 Dec 31; 179(7):1481-96.
Score: 0.016
-
Transgenesis upgrades for Drosophila melanogaster. Development. 2007 Oct; 134(20):3571-84.
Score: 0.016
-
Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development. J Cell Biol. 2007 Jul 16; 178(2):309-22.
Score: 0.016
-
P[acman]: a BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster. Science. 2006 Dec 15; 314(5806):1747-51.
Score: 0.015
-
Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity. PLoS Biol. 2006 Nov; 4(12):e416.
Score: 0.015
-
Activity-independent prespecification of synaptic partners in the visual map of Drosophila. Curr Biol. 2006 Sep 19; 16(18):1835-43.
Score: 0.015
-
Senseless physically interacts with proneural proteins and functions as a transcriptional co-activator. Development. 2006 May; 133(10):1979-89.
Score: 0.015
-
Internalization is required for proper Wingless signaling in Drosophila melanogaster. J Cell Biol. 2006 Apr 10; 173(1):95-106.
Score: 0.015
-
Senseless and Daughterless confer neuronal identity to epithelial cells in the Drosophila wing margin. Development. 2006 May; 133(9):1683-92.
Score: 0.015
-
The nicotinic acetylcholine receptor Dalpha7 is required for an escape behavior in Drosophila. PLoS Biol. 2006 Mar; 4(3):e63.
Score: 0.014
-
Fighting anthrax with flies. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3013-4.
Score: 0.014
-
Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors. Dev Cell. 2005 Sep; 9(3):351-63.
Score: 0.014
-
Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron. 2005 Aug 04; 47(3):365-78.
Score: 0.014
-
Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer. J Cell Biol. 2005 Jul 04; 170(1):127-39.
Score: 0.014
-
The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila. Cell. 2005 May 20; 121(4):607-620.
Score: 0.014
-
Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication. Mol Neurodegener. 2025 May 03; 20(1):51.
Score: 0.014
-
Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components. Neuron. 2005 Apr 21; 46(2):219-32.
Score: 0.014
-
De novo variants in CDKL1 and CDKL2 are associated with neurodevelopmental symptoms. Am J Hum Genet. 2025 Apr 03; 112(4):846-862.
Score: 0.014
-
Emerging technologies for gene manipulation in Drosophila melanogaster. Nat Rev Genet. 2005 Mar; 6(3):167-78.
Score: 0.014
-
Bonus, a Drosophila TIF1 homolog, is a chromatin-associated protein that acts as a modifier of position-effect variegation. Genetics. 2005 Feb; 169(2):783-94.
Score: 0.013
-
The architecture of the active zone in the presynaptic nerve terminal. Physiology (Bethesda). 2004 Oct; 19:262-70.
Score: 0.013
-
Gfi/Pag-3/senseless zinc finger proteins: a unifying theme? Mol Cell Biol. 2004 Oct; 24(20):8803-12.
Score: 0.013
-
Dap160/intersectin acts as a stabilizing scaffold required for synaptic development and vesicle endocytosis. Neuron. 2004 Jul 22; 43(2):193-205.
Score: 0.013
-
Loss-of-function in RBBP5 results in a syndromic neurodevelopmental disorder associated with microcephaly. Genet Med. 2024 Nov; 26(11):101218.
Score: 0.013
-
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Genetics. 2004 Jun; 167(2):761-81.
Score: 0.013
-
Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila. Nat Commun. 2024 Apr 18; 15(1):3326.
Score: 0.013
-
Hugo J. Bellen. Curr Biol. 2004 Mar 23; 14(6):R218.
Score: 0.013
-
Flying in the face of total disruption. Nat Genet. 2004 Mar; 36(3):211-2.
Score: 0.013
-
Identifying potential dietary treatments for inherited metabolic disorders using Drosophila nutrigenomics. Cell Rep. 2024 03 26; 43(3):113861.
Score: 0.013
-
The ins and outs of Wingless signaling. Trends Cell Biol. 2004 Jan; 14(1):45-53.
Score: 0.012
-
Senseless acts as a binary switch during sensory organ precursor selection. Genes Dev. 2003 Dec 01; 17(23):2966-78.
Score: 0.012
-
Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating. Neuron. 2003 Nov 13; 40(4):733-48.
Score: 0.012
-
Mapping Drosophila mutations with molecularly defined P element insertions. Proc Natl Acad Sci U S A. 2003 Sep 16; 100(19):10860-5.
Score: 0.012
-
Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development. Curr Biol. 2003 Aug 19; 13(16):1388-96.
Score: 0.012
-
Synaptotagmin I, a Ca2+ sensor for neurotransmitter release. Trends Neurosci. 2003 Aug; 26(8):413-22.
Score: 0.012
-
A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Cell Rep. 2023 08 29; 42(8):112842.
Score: 0.012
-
Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution. Science. 2023 06 16; 380(6650):eadg0934.
Score: 0.012
-
SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia. Brain. 2023 04 19; 146(4):1420-1435.
Score: 0.012
-
De novo variants in MRTFB have gain-of-function activity in Drosophila and are associated with a novel neurodevelopmental phenotype with dysmorphic features. Genet Med. 2023 06; 25(6):100833.
Score: 0.012
-
The fly homolog of SUPT16H, a gene associated with neurodevelopmental disorders, is required in a cell-autonomous fashion for cell survival. Hum Mol Genet. 2023 03 06; 32(6):984-997.
Score: 0.012
-
The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development. 2003 Jan; 130(1):221-32.
Score: 0.012
-
Drosophila as a diet discovery tool for treating amino acid disorders. Trends Endocrinol Metab. 2023 02; 34(2):85-105.
Score: 0.012
-
Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila. Elife. 2022 11 08; 11.
Score: 0.012
-
Synaptic vesicle retrieval: still time for a kiss. Nat Cell Biol. 2002 Nov; 4(11):E245-8.
Score: 0.011
-
De novo variants in EMC1 lead to neurodevelopmental delay and cerebellar degeneration and affect glial function in Drosophila. Hum Mol Genet. 2022 09 29; 31(19):3231-3244.
Score: 0.011
-
Loss of Activity-Induced Mitochondrial ATP Production Underlies the Synaptic Defects in a Drosophila Model of ALS. J Neurosci. 2022 10 19; 42(42):8019-8037.
Score: 0.011
-
Meaningless minis? Mechanisms of neurotransmitter-receptor clustering. Trends Neurosci. 2002 Aug; 25(8):383-5.
Score: 0.011
-
Numb: "Adapting" notch for endocytosis. Dev Cell. 2002 Aug; 3(2):155-6.
Score: 0.011
-
ANKLE2-related microcephaly: A variable microcephaly syndrome resembling Zika infection. Ann Clin Transl Neurol. 2022 08; 9(8):1276-1288.
Score: 0.011
-
Drosophila VAP-33A directs bouton formation at neuromuscular junctions in a dosage-dependent manner. Neuron. 2002 Jul 18; 35(2):291-306.
Score: 0.011
-
Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. Development. 2022 05 15; 149(10).
Score: 0.011
-
Endophilin mutations block clathrin-mediated endocytosis but not neurotransmitter release. Cell. 2002 Apr 05; 109(1):101-12.
Score: 0.011
-
Loss-of-function variants in TIAM1 are associated with developmental delay, intellectual disability, and seizures. Am J Hum Genet. 2022 04 07; 109(4):571-586.
Score: 0.011
-
Loss of Neuron Navigator 2 Impairs Brain and Cerebellar Development. Cerebellum. 2023 Apr; 22(2):206-222.
Score: 0.011
-
Daam2 Regulates Myelin Structure and the Oligodendrocyte Actin Cytoskeleton through Rac1 and Gelsolin. J Neurosci. 2022 03 02; 42(9):1679-1691.
Score: 0.011
-
Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell. 2002 Jan 25; 108(2):261-9.
Score: 0.011
-
pRIMing synaptic vesicles for fusion. Nat Neurosci. 2001 Oct; 4(10):965-6.
Score: 0.011
-
TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila. Am J Hum Genet. 2021 09 02; 108(9):1669-1691.
Score: 0.011
-
Neuroscience. The meaning of a mini. Science. 2001 Jul 20; 293(5529):443-4.
Score: 0.011
-
Heterozygous loss-of-function variants significantly expand the phenotypes associated with loss of GDF11. Genet Med. 2021 10; 23(10):1889-1900.
Score: 0.010
-
Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision. Orphanet J Rare Dis. 2021 05 07; 16(1):206.
Score: 0.010
-
Axon-glia interactions and the domain organization of myelinated axons requires neurexin IV/Caspr/Paranodin. Neuron. 2001 May; 30(2):369-83.
Score: 0.010
-
Bonus, a Drosophila homolog of TIF1 proteins, interacts with nuclear receptors and can inhibit betaFTZ-F1-dependent transcription. Mol Cell. 2001 Apr; 7(4):753-65.
Score: 0.010
-
The ROP-syntaxin interaction inhibits neurotransmitter release. Eur J Cell Biol. 2001 Feb; 80(2):196-9.
Score: 0.010
-
Drosophila Lyra mutations are gain-of-function mutations of senseless. Genetics. 2001 Jan; 157(1):307-15.
Score: 0.010
-
TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS. Elife. 2020 12 10; 9.
Score: 0.010
-
Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins. Genetics. 2000 Dec; 156(4):1691-715.
Score: 0.010
-
BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms. Am J Hum Genet. 2020 12 03; 107(6):1096-1112.
Score: 0.010
-
Low doses of the neonicotinoid insecticide imidacloprid induce ROS triggering neurological and metabolic impairments in Drosophila. Proc Natl Acad Sci U S A. 2020 10 13; 117(41):25840-25850.
Score: 0.010
-
The Daam2-VHL-Nedd4 axis governs developmental and regenerative oligodendrocyte differentiation. Genes Dev. 2020 09 01; 34(17-18):1177-1189.
Score: 0.010
-
Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila. Cell. 2000 Aug 04; 102(3):349-62.
Score: 0.010
-
Doing the MATH: is the mouse a good model for fly development? Genes Dev. 2000 Aug 01; 14(15):1852-65.
Score: 0.010
-
Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction. PLoS Genet. 2020 06; 16(6):e1008868.
Score: 0.010
-
De Novo Variants in CDK19 Are Associated with a Syndrome Involving Intellectual Disability and Epileptic Encephalopathy. Am J Hum Genet. 2020 05 07; 106(5):717-725.
Score: 0.010
-
Novel role of dynamin-related-protein 1 in dynamics of ER-lipid droplets in adipose tissue. FASEB J. 2020 06; 34(6):8265-8282.
Score: 0.010
-
Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain. Elife. 2020 04 14; 9.
Score: 0.010
-
A genome-wide search for synaptic vesicle cycle proteins in Drosophila. Neuron. 2000 Apr; 26(1):45-50.
Score: 0.010
-
Untying the Gordian knot of cytokinesis. Role of small G proteins and their regulators. J Cell Biol. 2000 Mar 06; 148(5):843-8.
Score: 0.010
-
atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain. Neuron. 2000 Mar; 25(3):549-61.
Score: 0.010
-
Use of the CRISPR-Cas9 System in Drosophila Cultured Cells to Introduce Fluorescent Tags into Endogenous Genes. Curr Protoc Mol Biol. 2020 Mar; 130(1):e112.
Score: 0.010
-
Tissue distribution of PEBBLE RNA and pebble protein during Drosophila embryonic development. Mech Dev. 2000 Feb; 90(2):269-73.
Score: 0.009
-
Ten years of enhancer detection: lessons from the fly. Plant Cell. 1999 Dec; 11(12):2271-81.
Score: 0.009
-
Loss of Oxidation Resistance 1, OXR1, Is Associated with an Autosomal-Recessive Neurological Disease with Cerebellar Atrophy and Lysosomal Dysfunction. Am J Hum Genet. 2019 12 05; 105(6):1237-1253.
Score: 0.009
-
Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders. Nat Commun. 2019 10 15; 10(1):4679.
Score: 0.009
-
Bi-allelic Variants in IQSEC1 Cause Intellectual Disability, Developmental Delay, and Short Stature. Am J Hum Genet. 2019 11 07; 105(5):907-920.
Score: 0.009
-
A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila. Genes Dev. 1999 Sep 01; 13(17):2301-14.
Score: 0.009
-
Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information. J Vis Exp. 2019 08 15; (150).
Score: 0.009
-
cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Rep. 2019 08 13; 28(7):1799-1813.e5.
Score: 0.009
-
De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia. Am J Hum Genet. 2019 08 01; 105(2):413-424.
Score: 0.009
-
Syntaxin 1A interacts with multiple exocytic proteins to regulate neurotransmitter release in vivo. Neuron. 1999 Jul; 23(3):593-605.
Score: 0.009
-
Loss of proteins associated with amyotrophic lateral sclerosis affects lysosomal acidification via different routes. Autophagy. 2019 08; 15(8):1467-1469.
Score: 0.009
-
Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity. Cell. 1999 Mar 19; 96(6):833-45.
Score: 0.009
-
Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification. Nat Cell Biol. 2019 03; 21(3):384-396.
Score: 0.009
-
Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis. Cell. 2018 12 13; 175(7):1931-1945.e18.
Score: 0.009
-
skittles, a Drosophila phosphatidylinositol 4-phosphate 5-kinase, is required for cell viability, germline development and bristle morphology, but not for neurotransmitter release. Genetics. 1998 Dec; 150(4):1527-37.
Score: 0.009
-
Synaptic vesicle size and number are regulated by a clathrin adaptor protein required for endocytosis. Neuron. 1998 Dec; 21(6):1465-75.
Score: 0.009
-
Interactions between the Ig-Superfamily Proteins DIP-a and Dpr6/10 Regulate Assembly of Neural Circuits. Neuron. 2018 12 19; 100(6):1369-1384.e6.
Score: 0.009
-
Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron. 2018 12 19; 100(6):1385-1400.e6.
Score: 0.009
-
Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease. N Engl J Med. 2018 11 29; 379(22):2131-2139.
Score: 0.009
-
Bi-allelic Loss-of-Function Variants in DNMBP Cause Infantile Cataracts. Am J Hum Genet. 2018 10 04; 103(4):568-578.
Score: 0.009
-
Neurexin IV, caspr and paranodin--novel members of the neurexin family: encounters of axons and glia. Trends Neurosci. 1998 Oct; 21(10):444-9.
Score: 0.009
-
Visual impairment and progressive phthisis bulbi caused by recessive pathogenic variant in MARK3. Hum Mol Genet. 2018 08 01; 27(15):2703-2711.
Score: 0.009
-
Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder. Hum Mol Genet. 2018 07 15; 27(14):2454-2465.
Score: 0.009
-
The fruit fly: a model organism to study the genetics of alcohol abuse and addiction? Cell. 1998 Jun 12; 93(6):909-12.
Score: 0.008
-
Using Drosophila to study mechanisms of hereditary hearing loss. Dis Model Mech. 2018 05 31; 11(6).
Score: 0.008
-
The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein. Development. 1998 May; 125(10):1845-56.
Score: 0.008
-
ROP, the Drosophila Sec1 homolog, interacts with syntaxin and regulates neurotransmitter release in a dosage-dependent manner. EMBO J. 1998 Jan 02; 17(1):127-39.
Score: 0.008
-
Pleiotropic neuropathological and biochemical alterations associated with Myo5a mutation in a rat Model. Brain Res. 2018 01 15; 1679:155-170.
Score: 0.008
-
Genetic dissection of synaptic transmission in Drosophila. Curr Opin Neurobiol. 1997 Oct; 7(5):624-30.
Score: 0.008
-
Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila. Genetics. 2017 10; 207(2):389-412.
Score: 0.008
-
Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially. PLoS Genet. 2017 Jul; 13(7):e1006905.
Score: 0.008
-
Lysosomal Degradation Is Required for Sustained Phagocytosis of Bacteria by Macrophages. Cell Host Microbe. 2017 Jun 14; 21(6):719-730.e6.
Score: 0.008
-
Deciphering the function of neurexins at cellular junctions. J Cell Biol. 1997 May 19; 137(4):793-6.
Score: 0.008
-
Developmental Expression of 4-Repeat-Tau Induces Neuronal Aneuploidy in Drosophila Tauopathy Models. Sci Rep. 2017 01 23; 7:40764.
Score: 0.008
-
A Drosophila neurexin is required for septate junction and blood-nerve barrier formation and function. Cell. 1996 Dec 13; 87(6):1059-68.
Score: 0.008
-
Chromatid segregation at anaphase requires the barren product, a novel chromosome-associated protein that interacts with Topoisomerase II. Cell. 1996 Dec 13; 87(6):1103-14.
Score: 0.008
-
Drosophila syntaxin is required for cell viability and may function in membrane formation and stabilization. Genetics. 1996 Dec; 144(4):1713-24.
Score: 0.008
-
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. PLoS Genet. 2016 Oct; 12(10):e1006327.
Score: 0.008
-
Recurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes. Am J Hum Genet. 2016 Oct 06; 99(4):831-845.
Score: 0.008
-
gutfeeling, a Drosophila gene encoding an antizyme-like protein, is required for late differentiation of neurons and muscles. Genetics. 1996 Sep; 144(1):183-96.
Score: 0.007
-
Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. Acta Neuropathol Commun. 2016 06 23; 4(1):62.
Score: 0.007
-
NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. PLoS Biol. 2016 06; 14(6):e1002472.
Score: 0.007
-
Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination. PLoS Genet. 2016 05; 12(5):e1006054.
Score: 0.007
-
Missense variants in the middle domain of DNM1L in cases of infantile encephalopathy alter peroxisomes and mitochondria when assayed in Drosophila. Hum Mol Genet. 2016 05 01; 25(9):1846-56.
Score: 0.007
-
Invertebrate versus vertebrate neurogenesis: variations on the same theme? Dev Genet. 1996; 18(1):1-10.
Score: 0.007
-
Ig Superfamily Ligand and Receptor Pairs Expressed in Synaptic Partners in Drosophila. Cell. 2015 Dec 17; 163(7):1756-69.
Score: 0.007
-
Control of Synaptic Connectivity by a Network of Drosophila IgSF Cell Surface Proteins. Cell. 2015 Dec 17; 163(7):1770-1782.
Score: 0.007
-
FlyBase: a virtual Drosophila cornucopia. Trends Genet. 1995 Nov; 11(11):456-7.
Score: 0.007
-
Pri sORF peptides induce selective proteasome-mediated protein processing. Science. 2015 Sep 18; 349(6254):1356-8.
Score: 0.007
-
Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure. Nat Commun. 2015 Sep 10; 6:8245.
Score: 0.007
-
FlyVar: a database for genetic variation in Drosophila melanogaster. Database (Oxford). 2015; 2015.
Score: 0.007
-
BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science. 2015 Aug 28; 349(6251):927-9.
Score: 0.007
-
Synaptotagmin controls and modulates synaptic-vesicle fusion in a Ca(2+)-dependent manner. Trends Neurosci. 1995 Apr; 18(4):177-83.
Score: 0.007
-
P-element mutations affecting embryonic peripheral nervous system development in Drosophila melanogaster. Genetics. 1995 Apr; 139(4):1663-78.
Score: 0.007
-
A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis. PLoS Biol. 2015 Mar; 13(3):e1002103.
Score: 0.007
-
Huntingtin functions as a scaffold for selective macroautophagy. Nat Cell Biol. 2015 Mar; 17(3):262-75.
Score: 0.007
-
Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission. Cell. 1995 Jan 27; 80(2):311-20.
Score: 0.007
-
Presynaptic proteins involved in exocytosis in Drosophila melanogaster: a genetic analysis. Invert Neurosci. 1995; 1(1):3-13.
Score: 0.007
-
Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants. Proc Natl Acad Sci U S A. 1994 Nov 08; 91(23):10888-92.
Score: 0.007
-
rop, a Drosophila homolog of yeast Sec1 and vertebrate n-Sec1/Munc-18 proteins, is a negative regulator of neurotransmitter release in vivo. Neuron. 1994 Nov; 13(5):1099-108.
Score: 0.007
-
A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission. Neuron. 2014 Nov 19; 84(4):764-77.
Score: 0.007
-
Genetic and phenotypic analysis of thirteen essential genes in cytological interval 22F1-2; 23B1-2 reveals novel genes required for neural development in Drosophila. Genetics. 1994 Sep; 138(1):111-23.
Score: 0.007
-
Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development. Neuron. 1994 Aug; 13(2):269-87.
Score: 0.006
-
The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll. Development. 1994 Apr; 120(4):885-99.
Score: 0.006
-
miR-9a minimizes the phenotypic impact of genomic diversity by buffering a transcription factor. Cell. 2013 Dec 19; 155(7):1556-67.
Score: 0.006
-
The amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality control. Hum Mol Genet. 2014 Apr 15; 23(8):1975-89.
Score: 0.006
-
Neuromusculin, a Drosophila gene expressed in peripheral neuronal precursors and muscles, encodes a cell adhesion molecule. Neuron. 1993 Oct; 11(4):673-87.
Score: 0.006
-
Mutational analysis of Drosophila synaptotagmin demonstrates its essential role in Ca(2+)-activated neurotransmitter release. Cell. 1993 Sep 24; 74(6):1125-34.
Score: 0.006
-
VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans. PLoS Genet. 2013; 9(9):e1003738.
Score: 0.006
-
NMNATs, evolutionarily conserved neuronal maintenance factors. Trends Neurosci. 2013 Nov; 36(11):632-40.
Score: 0.006
-
Protein phosphatase 1? limits ring canal constriction during Drosophila germline cyst formation. PLoS One. 2013; 8(7):e70502.
Score: 0.006
-
The dynamin-binding domains of Dap160/intersectin affect bulk membrane retrieval in synapses. J Cell Sci. 2013 Feb 15; 126(Pt 4):1021-31.
Score: 0.006
-
Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission. J Neurosci. 2012 Nov 07; 32(45):16018-30.
Score: 0.006
-
The Drosophila couch potato protein is expressed in nuclei of peripheral neuronal precursors and shows homology to RNA-binding proteins. Genes Dev. 1992 Nov; 6(11):2125-36.
Score: 0.006
-
An assay to detect in vivo Y chromosome loss in Drosophila wing disc cells. G3 (Bethesda). 2012 Sep; 2(9):1095-102.
Score: 0.006
-
Spectraplakins promote microtubule-mediated axonal growth by functioning as structural microtubule-associated proteins and EB1-dependent +TIPs (tip interacting proteins). J Neurosci. 2012 Jul 04; 32(27):9143-58.
Score: 0.006
-
The Drosophila couch potato gene: an essential gene required for normal adult behavior. Genetics. 1992 Jun; 131(2):365-75.
Score: 0.006
-
Mutations in the mitochondrial methionyl-tRNA synthetase cause a neurodegenerative phenotype in flies and a recessive ataxia (ARSAL) in humans. PLoS Biol. 2012; 10(3):e1001288.
Score: 0.006
-
Isolation of temperature-sensitive diphtheria toxins in yeast and their effects on Drosophila cells. Development. 1992 Mar; 114(3):787-96.
Score: 0.005
-
Secreted VAPB/ALS8 major sperm protein domains modulate mitochondrial localization and morphology via growth cone guidance receptors. Dev Cell. 2012 Feb 14; 22(2):348-62.
Score: 0.005
-
Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. Genetics. 2012 Mar; 190(3):931-40.
Score: 0.005
-
Drosophila P elements preferentially transpose to replication origins. Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38):15948-53.
Score: 0.005
-
Drosophila Ten-m and filamin affect motor neuron growth cone guidance. PLoS One. 2011; 6(8):e22956.
Score: 0.005
-
A cis-regulatory map of the Drosophila genome. Nature. 2011 Mar 24; 471(7339):527-31.
Score: 0.005
-
A genome-wide Drosophila screen for heat nociception identifies a2d3 as an evolutionarily conserved pain gene. Cell. 2010 Nov 12; 143(4):628-38.
Score: 0.005
-
A molecularly defined duplication set for the X chromosome of Drosophila melanogaster. Genetics. 2010 Dec; 186(4):1111-25.
Score: 0.005
-
Dissecting the complexity of the nervous system by enhancer detection. Bioessays. 1990 May; 12(5):199-204.
Score: 0.005
-
P-element-mediated enhancer detection allows rapid identification of developmentally regulated genes and cell specific markers in Drosophila. J Physiol (Paris). 1990; 84(1):33-41.
Score: 0.005
-
Tilting the balance between facilitatory and inhibitory functions of mammalian and Drosophila Complexins orchestrates synaptic vesicle exocytosis. Neuron. 2009 Nov 12; 64(3):367-80.
Score: 0.005
-
P-element-mediated enhancer detection: a versatile method to study development in Drosophila. Genes Dev. 1989 Sep; 3(9):1288-300.
Score: 0.005
-
Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster. Nat Methods. 2009 Jun; 6(6):431-4.
Score: 0.005
-
A novel neuronal pathway for visually guided escape in Drosophila melanogaster. J Neurophysiol. 2009 Aug; 102(2):875-85.
Score: 0.005
-
Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm. Neuron. 2008 Jan 10; 57(1):27-40.
Score: 0.004
-
V-ATPase V0 sector subunit a1 in neurons is a target of calmodulin. J Biol Chem. 2008 Jan 04; 283(1):294-300.
Score: 0.004
-
Two Drosophila learning mutants, dunce and rutabaga, provide evidence of a maternal role for cAMP on embryogenesis. Dev Biol. 1987 Jun; 121(2):432-44.
Score: 0.004
-
Thirty-one flavors of Drosophila rab proteins. Genetics. 2007 Jun; 176(2):1307-22.
Score: 0.004
-
Sexual hyperactivity and reduced longevity of dunce females of Drosophila melanogaster. Genetics. 1987 Jan; 115(1):153-60.
Score: 0.004
-
Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15; 19(20):2412-7.
Score: 0.004
-
Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo. Nat Struct Mol Biol. 2005 Oct; 12(10):879-85.
Score: 0.004
-
The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins. Cell. 2005 Aug 26; 122(4):633-44.
Score: 0.003
-
Charlatan, a Zn-finger transcription factor, establishes a novel level of regulation of the proneural achaete/scute genes of Drosophila. Development. 2005 Mar; 132(6):1211-22.
Score: 0.003
-
Heterogeneity of Es-1 esterases in the rabbit (Oryctolagus cuniculus). Biochem Genet. 1984 Oct; 22(9-10):853-70.
Score: 0.003
-
Growth factor independence-1 is expressed in primary human neuroendocrine lung carcinomas and mediates the differentiation of murine pulmonary neuroendocrine cells. Cancer Res. 2004 Oct 01; 64(19):6874-82.
Score: 0.003
-
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress. Development. 2004 May; 131(9):2183-94.
Score: 0.003
-
Endophilin promotes a late step in endocytosis at glial invaginations in Drosophila photoreceptor terminals. J Neurosci. 2003 Nov 19; 23(33):10732-44.
Score: 0.003
-
Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila. Development. 2002 Dec; 129(24):5719-30.
Score: 0.003
-
Drosophila atonal fully rescues the phenotype of Math1 null mice: new functions evolve in new cellular contexts. Curr Biol. 2002 Sep 17; 12(18):1611-6.
Score: 0.003
-
When cell biology meets development: endocytic regulation of signaling pathways. Genes Dev. 2002 Jun 01; 16(11):1314-36.
Score: 0.003
-
Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres. Nature. 2002 Mar 14; 416(6877):178-83.
Score: 0.003
-
Enhancement of presynaptic calcium current by cysteine string protein. J Physiol. 2002 Jan 15; 538(Pt 2):383-9.
Score: 0.003
-
Mapping and identification of essential gene functions on the X chromosome of Drosophila. EMBO Rep. 2002 Jan; 3(1):34-8.
Score: 0.003
-
Targeted mutations in the syntaxin H3 domain specifically disrupt SNARE complex function in synaptic transmission. J Neurosci. 2001 Dec 01; 21(23):9142-50.
Score: 0.003
-
senseless repression of rough is required for R8 photoreceptor differentiation in the developing Drosophila eye. Neuron. 2001 Nov 08; 32(3):403-14.
Score: 0.003
-
Proprioceptor pathway development is dependent on Math1. Neuron. 2001 May; 30(2):411-22.
Score: 0.003
-
A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis. Curr Biol. 2001 Mar 06; 11(5):295-307.
Score: 0.003
-
Functional conservation of atonal and Math1 in the CNS and PNS. Development. 2000 Mar; 127(5):1039-48.
Score: 0.002
-
Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction. Cell. 2000 Feb 18; 100(4):447-56.
Score: 0.002
-
Tailoring uniform coats for synaptic vesicles during endocytosis. Neuron. 1999 Jul; 23(3):419-22.
Score: 0.002
-
Math1: an essential gene for the generation of inner ear hair cells. Science. 1999 Jun 11; 284(5421):1837-41.
Score: 0.002
-
pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis. Genes Dev. 1998 May 15; 12(10):1483-94.
Score: 0.002
-
P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: mutations affecting embryonic PNS development. Genetics. 1997 Dec; 147(4):1723-41.
Score: 0.002
-
Math1 is essential for genesis of cerebellar granule neurons. Nature. 1997 Nov 13; 390(6656):169-72.
Score: 0.002
-
Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis. Hum Mol Genet. 1996 Sep; 5(9):1207-16.
Score: 0.002
-
Identification of immune system and response genes, and novel mutations causing melanotic tumor formation in Drosophila melanogaster. Genetics. 1996 Jun; 143(2):929-40.
Score: 0.002
-
Syntaxin and synaptobrevin function downstream of vesicle docking in Drosophila. Neuron. 1995 Sep; 15(3):663-73.
Score: 0.002
-
Absence of synaptotagmin disrupts excitation-secretion coupling during synaptic transmission. Proc Natl Acad Sci U S A. 1994 Oct 25; 91(22):10727-31.
Score: 0.002
-
Expression of synaptotagmin in Drosophila reveals transport and localization of synaptic vesicles to the synapse. Development. 1993 Aug; 118(4):1077-88.
Score: 0.002
-
Position effects on eukaryotic gene expression. Annu Rev Cell Biol. 1990; 6:679-714.
Score: 0.001
-
P-element-mediated enhancer detection applied to the study of oogenesis in Drosophila. Development. 1989 Oct; 107(2):189-200.
Score: 0.001
-
P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila. Genes Dev. 1989 Sep; 3(9):1301-13.
Score: 0.001