Connection

MALCOLM BRENNER to Genetic Therapy

This is a "connection" page, showing publications MALCOLM BRENNER has written about Genetic Therapy.
Connection Strength

7.424
  1. Improving the safety of T-Cell therapies using an inducible caspase-9 gene. Exp Hematol. 2016 Nov; 44(11):1013-1019.
    View in: PubMed
    Score: 0.389
  2. Mesenchymal Stromal Cells for Linked Delivery of Oncolytic and Apoptotic Adenoviruses to Non-small-cell Lung Cancers. Mol Ther. 2015 Sep; 23(9):1497-506.
    View in: PubMed
    Score: 0.361
  3. An Inducible Caspase-9 Suicide Gene to Improve the Safety of Therapy Using Human Induced Pluripotent Stem Cells. Mol Ther. 2015 Sep; 23(9):1475-85.
    View in: PubMed
    Score: 0.359
  4. Is cancer gene therapy an empty suit? Lancet Oncol. 2013 Oct; 14(11):e447-e456.
    View in: PubMed
    Score: 0.320
  5. Introducing molecular therapy--methods & clinical development. Mol Ther. 2013 Jun; 21(6):1105.
    View in: PubMed
    Score: 0.313
  6. Introducing a new ASGCT forum for publication of methodology and clinical development in gene, cell, and oligonucleotide therapies. Mol Ther. 2012 Nov; 20(11):2005-6.
    View in: PubMed
    Score: 0.301
  7. Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. Blood. 2011 Dec 01; 118(23):6050-6.
    View in: PubMed
    Score: 0.279
  8. The eyes have it. Mol Ther. 2010 Mar; 18(3):451-2.
    View in: PubMed
    Score: 0.250
  9. Fifteen years of gene therapy based on chimeric antigen receptors: "are we nearly there yet?". Hum Gene Ther. 2009 Nov; 20(11):1229-39.
    View in: PubMed
    Score: 0.244
  10. Overview of gene therapy clinical progress including cancer treatment with gene-modified T cells. Hematology Am Soc Hematol Educ Program. 2009; 675-81.
    View in: PubMed
    Score: 0.230
  11. The continuing contribution of gene marking to cell and gene therapy. Mol Ther. 2007 Apr; 15(4):666-76.
    View in: PubMed
    Score: 0.202
  12. Targeted delivery of adenoviral vectors by cytotoxic T cells. Blood. 2004 Oct 15; 104(8):2272-80.
    View in: PubMed
    Score: 0.167
  13. Chimeric T-cell receptors for the targeting of cancer cells. Acta Haematol. 2003; 110(2-3):154-9.
    View in: PubMed
    Score: 0.152
  14. Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas. J Immunother Cancer. 2021 05; 9(5).
    View in: PubMed
    Score: 0.135
  15. Gene transfer and the treatment of haematological malignancy. J Intern Med. 2001 Apr; 249(4):345-58.
    View in: PubMed
    Score: 0.135
  16. Phase I study of chemokine and cytokine gene-modified autologous neuroblastoma cells for treatment of relapsed/refractory neuroblastoma using an adenoviral vector. Hum Gene Ther. 2000 Jul 01; 11(10):1477-88.
    View in: PubMed
    Score: 0.128
  17. Reports of adenovector "death" are greatly exaggerated. Mol Ther. 2000 Mar; 1(3):205.
    View in: PubMed
    Score: 0.125
  18. Gene transfer by adenovectors. Blood. 1999 Dec 15; 94(12):3965-7.
    View in: PubMed
    Score: 0.123
  19. "Resistance is futile". Gene Ther. 1999 Oct; 6(10):1646-7.
    View in: PubMed
    Score: 0.121
  20. "The end of the beginning": molecular and cellular biology of gene therapy keystone. 14-20 January 1999. Biochim Biophys Acta. 1999 Jul 29; 1424(1):R5-9.
    View in: PubMed
    Score: 0.120
  21. Thymic lymphoproliferative disease after successful correction of CD40 ligand deficiency by gene transfer in mice. Nat Med. 1998 Nov; 4(11):1253-60.
    View in: PubMed
    Score: 0.114
  22. Interleukin-2 gene-modified allogeneic tumor cells for treatment of relapsed neuroblastoma. Hum Gene Ther. 1998 Jun 10; 9(9):1303-11.
    View in: PubMed
    Score: 0.111
  23. Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma. J Clin Oncol. 2018 04 10; 36(11):1128-1139.
    View in: PubMed
    Score: 0.108
  24. Applications of gene transfer in hematologic malignancy. Recent Results Cancer Res. 1998; 144:60-9.
    View in: PubMed
    Score: 0.107
  25. Gene and cell transfer for specific immunotherapy. Vox Sang. 1998; 74 Suppl 2:87-90.
    View in: PubMed
    Score: 0.107
  26. Seek and You Will Not Find: Ending the Hunt for Replication-Competent Retroviruses during Human Gene Therapy. Mol Ther. 2018 01 03; 26(1):1-2.
    View in: PubMed
    Score: 0.107
  27. Hematological malignancies. FASEB J. 1997 Jul; 11(8):640-8.
    View in: PubMed
    Score: 0.104
  28. Emerging applications of gene transfer in the hematopoietic cancers. J Pediatr Hematol Oncol. 1997 Jan-Feb; 19(1):1-6.
    View in: PubMed
    Score: 0.100
  29. Gene transfer in haematological malignancy. Ann Med. 1996 Dec; 28(6):491-7.
    View in: PubMed
    Score: 0.100
  30. Gene marking and gene therapy for transplantation medicine. J Hematother. 1996 Oct; 5(5):553-5.
    View in: PubMed
    Score: 0.099
  31. Gene marking. Gene Ther. 1996 Apr; 3(4):278-9.
    View in: PubMed
    Score: 0.095
  32. The contribution of marker gene studies to hemopoietic stem cell therapies. Stem Cells. 1995 Sep; 13(5):453-61.
    View in: PubMed
    Score: 0.091
  33. A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy. Stem Cell Reports. 2015 Oct 13; 5(4):597-608.
    View in: PubMed
    Score: 0.091
  34. Human somatic gene therapy: progress and problems. J Intern Med. 1995 Mar; 237(3):229-39.
    View in: PubMed
    Score: 0.088
  35. The use of cytokines to improve gene transfer to human hematopoietic stem cells. Cytokines Mol Ther. 1995 Mar; 1(1):3-9.
    View in: PubMed
    Score: 0.088
  36. Gene transfer into human hemopoietic progenitor cells. Br Med Bull. 1995 Jan; 51(1):167-91.
    View in: PubMed
    Score: 0.087
  37. Genetic marking and manipulation of hematopoietic progenitor cells using retroviral vectors. Immunomethods. 1994 Dec; 5(3):204-10.
    View in: PubMed
    Score: 0.087
  38. Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins. J Clin Oncol. 2014 Mar 10; 32(8):798-808.
    View in: PubMed
    Score: 0.081
  39. Clinical success of complex biological therapies: be careful what you wish for... Mol Ther. 2010 Oct; 18(10):1737-8.
    View in: PubMed
    Score: 0.065
  40. Progress and prospects: gene therapy clinical trials (part 2). Gene Ther. 2007 Nov; 14(22):1555-63.
    View in: PubMed
    Score: 0.053
  41. An inducible caspase 9 safety switch for T-cell therapy. Blood. 2005 Jun 01; 105(11):4247-54.
    View in: PubMed
    Score: 0.044
  42. LOAd703, an oncolytic virus-based immunostimulatory gene therapy, combined with chemotherapy for unresectable or metastatic pancreatic cancer (LOKON001): results from arm 1 of a non-randomised, single-centre, phase 1/2 study. Lancet Oncol. 2024 Apr; 25(4):488-500.
    View in: PubMed
    Score: 0.041
  43. Liposomal enhancement of the antitumor activity of conditionally replication-competent adenoviral plasmids. Mol Ther. 2004 Apr; 9(4):489-95.
    View in: PubMed
    Score: 0.041
  44. American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells. Mol Ther. 2003 Aug; 8(2):180-7.
    View in: PubMed
    Score: 0.040
  45. Expression of a fusogenic membrane glycoprotein by an oncolytic herpes simplex virus potentiates the viral antitumor effect. Mol Ther. 2003 Jun; 7(6):748-54.
    View in: PubMed
    Score: 0.039
  46. [Gene therapy of childhood cancers: current status and perspectives]. Bull Cancer. 2003 Mar; 90(3):227-38.
    View in: PubMed
    Score: 0.038
  47. Is retroviral gene marking too dangerous to use? Cytotherapy. 2003; 5(3):190-3.
    View in: PubMed
    Score: 0.038
  48. Replication competent retrovirus testing (RCR) in the National Gene Vector Biorepository: No evidence of RCR in 1,595 post-treatment peripheral blood samples obtained from 60 clinical trials. Mol Ther. 2023 03 01; 31(3):801-809.
    View in: PubMed
    Score: 0.038
  49. Cancer vaccines: dream, reality, or nightmare? Clin Exp Med. 2002 Nov; 2(3):109-18.
    View in: PubMed
    Score: 0.038
  50. Evidence-based regulation--a personal view. Mol Ther. 2002 Aug; 6(2):137.
    View in: PubMed
    Score: 0.037
  51. Response to "systemic adenovirus delivery". Mol Ther. 2002 Aug; 6(2):138.
    View in: PubMed
    Score: 0.037
  52. Bilamellar cationic liposomes protect adenovectors from preexisting humoral immune responses. Mol Ther. 2002 Mar; 5(3):233-41.
    View in: PubMed
    Score: 0.036
  53. Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen: a potential treatment strategy for Epstein-Barr virus--positive Hodgkin's lymphoma. Int J Cancer. 2001 Sep 01; 93(5):706-13.
    View in: PubMed
    Score: 0.035
  54. Efficient infection of primitive hematopoietic stem cells by modified adenovirus. Gene Ther. 2001 Jun; 8(12):930-7.
    View in: PubMed
    Score: 0.034
  55. Selection of human antitumor single-chain Fv antibodies from the B-cell repertoire of patients immunized against autologous neuroblastoma. Med Pediatr Oncol. 2000 Dec; 35(6):692-5.
    View in: PubMed
    Score: 0.033
  56. Administration of neomycin resistance gene-marked EBV-specific cytotoxic T-lymphocytes as therapy for patients receiving a bone marrow transplant for relapsed EBV-positive Hodgkin disease. Hum Gene Ther. 2000 Jul 01; 11(10):1465-75.
    View in: PubMed
    Score: 0.032
  57. Human gene marker/therapy clinical protocols. Hum Gene Ther. 2000 Apr 10; 11(6):919-79.
    View in: PubMed
    Score: 0.031
  58. Human gene marker/therapy clinical protocols. Hum Gene Ther. 1999 Dec 10; 10(18):3067-123.
    View in: PubMed
    Score: 0.031
  59. Cure of leukemia. Semin Hematol. 1999 Oct; 36(4 Suppl 7):73-83.
    View in: PubMed
    Score: 0.030
  60. Retinoblastoma treatment. Science. 1999 Jul 30; 285(5428):663-4.
    View in: PubMed
    Score: 0.030
  61. Gene therapy in a rodent model of Parkinson's disease using differentiated C6 cells expressing a GFAP-tyrosine hydroxylase transgene. Life Sci. 1999; 65(5):483-91.
    View in: PubMed
    Score: 0.029
  62. Astrocyte-specific expression of tyrosine hydroxylase after intracerebral gene transfer induces behavioral recovery in experimental parkinsonism. Gene Ther. 1998 Dec; 5(12):1650-5.
    View in: PubMed
    Score: 0.029
  63. Selective killing of glioma cell lines using an astrocyte-specific expression of the herpes simplex virus-thymidine kinase gene. Cancer Res. 1998 Oct 15; 58(20):4577-80.
    View in: PubMed
    Score: 0.028
  64. Human gene marker/therapy clinical protocols. Hum Gene Ther. 1997 Dec 10; 8(18):2301-38.
    View in: PubMed
    Score: 0.027
  65. Human gene marker/therapy clinical protocols. Hum Gene Ther. 1996 Dec 01; 7(18):2287-313.
    View in: PubMed
    Score: 0.025
  66. Human gene marker/therapy clinical protocols. Hum Gene Ther. 1996 Aug 20; 7(13):1621-47.
    View in: PubMed
    Score: 0.024
  67. Gene transfer to hematopoietic cells. N Engl J Med. 1996 Aug 01; 335(5):337-9.
    View in: PubMed
    Score: 0.024
  68. Gene transfer and therapeutic drug monitoring. Ther Drug Monit. 1996 Aug; 18(4):322-7.
    View in: PubMed
    Score: 0.024
  69. Gene therapy: socioeconomic and ethical issues. A roundtable discussion. Hum Gene Ther. 1996 Jun 10; 7(9):1139-44.
    View in: PubMed
    Score: 0.024
  70. Vectors in cancer therapy: how will they deliver? Cancer Gene Ther. 1995 Dec; 2(4):291-7.
    View in: PubMed
    Score: 0.023
  71. Stereotactic injection of herpes simplex thymidine kinase vector producer cells (PA317-G1Tk1SvNa.7) and intravenous ganciclovir for the treatment of progressive or recurrent primary supratentorial pediatric malignant brain tumors. Hum Gene Ther. 1995 Sep; 6(9):1231-55.
    View in: PubMed
    Score: 0.023
  72. European School of Oncology position paper. Gene therapy for the medical oncologist. Eur J Cancer. 1995; 31A(9):1531-7.
    View in: PubMed
    Score: 0.022
  73. Gene transfer into human hematopoietic progenitor cells: a review of current clinical protocols. J Hematother. 1993; 2(1):7-17.
    View in: PubMed
    Score: 0.019
  74. A phase 1/2 study of autologous neuroblastoma tumor cells genetically modified to secrete IL-2 in patients with high-risk neuroblastoma. J Immunother. 2008 Nov-Dec; 31(9):812-9.
    View in: PubMed
    Score: 0.014
  75. Selection of chronic lymphocytic leukemia binding peptides. Cancer Res. 2003 Sep 01; 63(17):5213-7.
    View in: PubMed
    Score: 0.010
  76. Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity. Blood. 2002 May 01; 99(9):3179-87.
    View in: PubMed
    Score: 0.009
  77. Controversies and new approaches to treatment of Langerhans cell histiocytosis. Hematol Oncol Clin North Am. 1998 Apr; 12(2):339-57.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.