MICHAEL MANCINI to Humans
This is a "connection" page, showing publications MICHAEL MANCINI has written about Humans.
Connection Strength
0.536
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SPACe: an open-source, single-cell analysis of Cell Painting data. Nat Commun. 2024 Nov 23; 15(1):10170.
Score: 0.026
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Age bias in the criteria for antisocial personality disorder. J Psychiatr Res. 2021 05; 137:444-451.
Score: 0.020
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Single-Cell Distribution Analysis of AR Levels by High-Throughput Microscopy in Cell Models: Application for Testing Endocrine-Disrupting Chemicals. SLAS Discov. 2020 08; 25(7):684-694.
Score: 0.019
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A Mechanistic High-Content Analysis Assay Using a Chimeric Androgen Receptor That Rapidly Characterizes Androgenic Chemicals. SLAS Discov. 2020 08; 25(7):695-708.
Score: 0.019
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Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells. PLoS One. 2019; 14(11):e0224405.
Score: 0.019
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Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis. PLoS One. 2017; 12(7):e0180141.
Score: 0.016
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High-Content Screening Identifies Src Family Kinases as Potential Regulators of AR-V7 Expression and Androgen-Independent Cell Growth. Prostate. 2017 01; 77(1):82-93.
Score: 0.015
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High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator. Oncotarget. 2016 Mar 29; 7(13):16962-74.
Score: 0.014
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Use of HCA in subproteome-immunization and screening of hybridoma supernatants to define distinct antibody binding patterns. Methods. 2016 Mar 01; 96:75-84.
Score: 0.014
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Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays. Chem Biol. 2014 Jun 19; 21(6):743-53.
Score: 0.013
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Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-a protein levels and activity. Oncogene. 2015 Jan 08; 34(2):154-64.
Score: 0.012
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Coactivators enable glucocorticoid receptor recruitment to fine-tune estrogen receptor transcriptional responses. Nucleic Acids Res. 2013 Apr; 41(7):4036-48.
Score: 0.012
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Feed-forward inhibition of androgen receptor activity by glucocorticoid action in human adipocytes. Chem Biol. 2012 Sep 21; 19(9):1126-41.
Score: 0.011
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A framework for image-based classification of mitotic cells in asynchronous populations. Assay Drug Dev Technol. 2012 Apr; 10(2):161-78.
Score: 0.011
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High content imaging-based assay to classify estrogen receptor-a ligands based on defined mechanistic outcomes. Gene. 2011 May 15; 477(1-2):42-52.
Score: 0.010
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Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis. J Cell Biol. 2011 Jan 10; 192(1):55-67.
Score: 0.010
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Automated microscopy and image analysis for androgen receptor function. Methods Mol Biol. 2011; 776:313-31.
Score: 0.010
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Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects. PLoS One. 2008; 3(11):e3605.
Score: 0.009
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Activation of estrogen receptor-alpha by E2 or EGF induces temporally distinct patterns of large-scale chromatin modification and mRNA transcription. PLoS One. 2008 May 28; 3(5):e2286.
Score: 0.008
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Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Mol Cell Biol. 2007 Oct; 27(19):6913-32.
Score: 0.008
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Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent. J Cell Sci. 2006 Oct 01; 119(Pt 19):4101-16.
Score: 0.007
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Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility. J Cell Biochem. 2006 Jul 01; 98(4):770-88.
Score: 0.007
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High-resolution, high-throughput microscopy analyses of nuclear receptor and coregulator function. Methods Enzymol. 2006; 414:188-210.
Score: 0.007
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Molecular dynamics and nuclear receptor function. Trends Endocrinol Metab. 2005 Jan-Feb; 16(1):12-8.
Score: 0.007
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Inactivating Pit-1 mutations alter subnuclear dynamics suggesting a protein misfolding and nuclear stress response. J Cell Biochem. 2004 Jul 01; 92(4):664-78.
Score: 0.006
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eEF1A2 promotes PTEN-GSK3?-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer. Sci Signal. 2024 03 05; 17(826):eadh4475.
Score: 0.006
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Helping families heal in substance use treatment: A qualitative study about the role of peer support specialists with client families. J Subst Use Addict Treat. 2023 05; 148:209024.
Score: 0.006
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A systematic review of recurrent firearm injury rates in the United States. Prev Med. 2023 03; 168:107443.
Score: 0.006
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Intranuclear ataxin1 inclusions contain both fast- and slow-exchanging components. Nat Cell Biol. 2002 Oct; 4(10):806-10.
Score: 0.006
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Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation. Mol Cell. 2021 08 19; 81(16):3368-3385.e9.
Score: 0.005
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Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells. Sci Rep. 2021 05 17; 11(1):10461.
Score: 0.005
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Identification of celastrol as a novel HIV-1 latency reversal agent by an image-based screen. PLoS One. 2021; 16(4):e0244771.
Score: 0.005
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The Cdk9 and cyclin T subunits of TAK/P-TEFb localize to splicing factor-rich nuclear speckle regions. J Cell Sci. 2001 Apr; 114(Pt 8):1491-503.
Score: 0.005
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The Human Nose Organoid Respiratory Virus Model: an Ex Vivo Human Challenge Model To Study Respiratory Syncytial Virus (RSV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Pathogenesis and Evaluate Therapeutics. mBio. 2021 02 22; 13(1):e0351121.
Score: 0.005
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FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nat Cell Biol. 2001 Jan; 3(1):15-23.
Score: 0.005
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Prevalence and correlates of antisocial personality disorder in older adults. Aging Ment Health. 2022 01; 26(1):169-178.
Score: 0.005
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Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms. PLoS Comput Biol. 2020 09; 16(9):e1008191.
Score: 0.005
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Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes. Mol Cell. 2020 09 03; 79(5):812-823.e4.
Score: 0.005
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Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1. Mol Endocrinol. 2000 Apr; 14(4):518-34.
Score: 0.005
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The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis. Nucleic Acids Res. 2020 03 18; 48(5):2621-2642.
Score: 0.005
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Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity. Nucleic Acids Res. 2020 02 28; 48(4):1800-1810.
Score: 0.005
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Subnuclear dynamics and transcription factor function. J Cell Biochem Suppl. 2000; Suppl 35:99-106.
Score: 0.005
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Validation Studies for Single Circulating Trophoblast Genetic Testing as a Form of Noninvasive Prenatal Diagnosis. Am J Hum Genet. 2019 12 05; 105(6):1262-1273.
Score: 0.005
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Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone. Hum Mol Genet. 1999 May; 8(5):731-41.
Score: 0.004
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Subnuclear partitioning and functional regulation of the Pit-1 transcription factor. J Cell Biochem. 1999 Mar 01; 72(3):322-38.
Score: 0.004
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Measuring Mobility in Chromatin by Intensity-Sorted FCS. Biophys J. 2019 03 19; 116(6):987-999.
Score: 0.004
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Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage. Cell. 2019 01 10; 176(1-2):127-143.e24.
Score: 0.004
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Bexarotene - a novel modulator of AURKA and the primary cilium in VHL-deficient cells. J Cell Sci. 2018 12 14; 131(24).
Score: 0.004
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Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation. J Cell Sci. 1998 Dec; 111 ( Pt 23):3497-506.
Score: 0.004
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Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells. Sci Rep. 2018 09 03; 8(1):13134.
Score: 0.004
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Functional subnuclear partitioning of transcription factors. J Cell Biochem. 1998 Aug 01; 70(2):213-21.
Score: 0.004
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Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies. Nat Commun. 2017 04 21; 8:15045.
Score: 0.004
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Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming. Nature. 2017 04 13; 544(7649):250-254.
Score: 0.004
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Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. Sci Rep. 2017 01 27; 7:41389.
Score: 0.004
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Dynamic continuity of nuclear and mitotic matrix proteins in the cell cycle. J Cell Biochem. 1996 Aug; 62(2):158-64.
Score: 0.004
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The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker. Prostate. 2016 10; 76(14):1271-84.
Score: 0.004
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Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer. Nat Commun. 2016 05 19; 7:11612.
Score: 0.004
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CUDC-101, a Novel Inhibitor of Full-Length Androgen Receptor (flAR) and Androgen Receptor Variant 7 (AR-V7) Activity: Mechanism of Action and In Vivo Efficacy. Horm Cancer. 2016 06; 7(3):196-210.
Score: 0.004
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Differential Regulation of Progesterone Receptor-Mediated Transcription by CDK2 and DNA-PK. Mol Endocrinol. 2016 Feb; 30(2):158-72.
Score: 0.004
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Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10; 28(2):240-52.
Score: 0.003
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Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes. Mol Endocrinol. 2015 Sep; 29(9):1320-33.
Score: 0.003
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The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. PLoS Genet. 2014 Jun; 10(6):e1004451.
Score: 0.003
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Unraveling the regulatory connections between two controllers of breast cancer cell fate. Nucleic Acids Res. 2014 Jun; 42(11):6839-49.
Score: 0.003
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Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer. Oncogene. 2015 Mar 12; 34(11):1341-53.
Score: 0.003
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Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis. PLoS One. 2013; 8(2):e55511.
Score: 0.003
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Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor a target gene activation. Proc Natl Acad Sci U S A. 2012 Aug 14; 109(33):13331-6.
Score: 0.003
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The activity of the androgen receptor variant AR-V7 is regulated by FOXO1 in a PTEN-PI3K-AKT-dependent way. Prostate. 2013 Feb 15; 73(3):267-77.
Score: 0.003
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Cancer-preventive rexinoid modulates neutral lipid contents of mammary epithelial cells through a peroxisome proliferator-activated receptor ?-dependent mechanism. Mol Pharmacol. 2012 Feb; 81(2):228-38.
Score: 0.003
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Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine. Adv Exp Med Biol. 2011; 707:63-5.
Score: 0.003
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Ligand-induced large-scale chromatin dynamics as a biosensor for the detection of estrogen receptor subtype selective ligands. Gene. 2010 Jun 15; 458(1-2):37-44.
Score: 0.002
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The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen. J Cell Sci. 2010 Apr 15; 123(Pt 8):1253-61.
Score: 0.002
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SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell. 2010 Feb 12; 37(3):321-32.
Score: 0.002
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Discovery and mechanistic characterization of a novel selective nuclear androgen receptor exporter for the treatment of prostate cancer. Cancer Res. 2010 Jan 15; 70(2):842-51.
Score: 0.002
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Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine. PLoS One. 2009 Dec 09; 4(12):e8179.
Score: 0.002
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Aurora-C kinase supports mitotic progression in the absence of Aurora-B. Cell Cycle. 2009 Sep 15; 8(18):2984-94.
Score: 0.002
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Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1. Mol Endocrinol. 2009 Sep; 23(9):1335-45.
Score: 0.002
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A cell line derived from non-neoplastic human neuroretinal cells. Invest Ophthalmol Vis Sci. 1989 Mar; 30(3):499-508.
Score: 0.002
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Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305. Breast Cancer Res Treat. 2010 Jan; 119(1):71-85.
Score: 0.002
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Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end. J Biol Chem. 2007 Nov 30; 282(48):34958-67.
Score: 0.002
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Plasma membrane assays and three-compartment image cytometry for high content screening. Assay Drug Dev Technol. 2007 Feb; 5(1):29-48.
Score: 0.002
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The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle. Mol Endocrinol. 2007 Feb; 21(2):359-75.
Score: 0.002
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Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy. J Cell Sci. 2005 Jul 01; 118(Pt 13):2923-33.
Score: 0.002
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Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence. Cancer Res. 2004 Oct 01; 64(19):7156-68.
Score: 0.002
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Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha. Mol Cell Biol. 2004 May; 24(10):4465-75.
Score: 0.002
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The dynamic mobility of histone H1 is regulated by cyclin/CDK phosphorylation. Mol Cell Biol. 2003 Dec; 23(23):8626-36.
Score: 0.002
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Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. Cell Motil Cytoskeleton. 2003 Jun; 55(2):134-46.
Score: 0.001
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Alteration of large-scale chromatin structure by estrogen receptor. Mol Cell Biol. 2002 May; 22(10):3437-49.
Score: 0.001
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Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA. Hum Mol Genet. 2000 Mar 01; 9(4):477-88.
Score: 0.001
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Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. Nat Genet. 1998 Jun; 19(2):148-54.
Score: 0.001
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Retinal dystrophy: development retarded by galactose feeding in spontaneously hypertensive rats. Science. 1986 Jan 24; 231(4736):376-8.
Score: 0.000