DAVID POPLACK to Methotrexate
This is a "connection" page, showing publications DAVID POPLACK has written about Methotrexate.
Connection Strength
1.729
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Methotrexate distribution within the subarachnoid space after intraventricular and intravenous administration. Cancer Chemother Pharmacol. 2000; 45(3):259-64.
Score: 0.146
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Methotrexate pharmacokinetics following administration of recombinant carboxypeptidase-G2 in rhesus monkeys. J Clin Oncol. 1992 Aug; 10(8):1359-64.
Score: 0.087
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Rescue of experimental intrathecal methotrexate overdose with carboxypeptidase-G2. J Clin Oncol. 1991 Apr; 9(4):670-4.
Score: 0.080
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A rhesus monkey model for continuous infusion of drugs into cerebrospinal fluid. Lab Anim Sci. 1990 Sep; 40(5):520-5.
Score: 0.077
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Memory and learning sequelae in long-term survivors of acute lymphoblastic leukemia: association with attention deficits. Am J Pediatr Hematol Oncol. 1990; 12(2):174-81.
Score: 0.073
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Chronopharmacokinetics of oral methotrexate and 6-mercaptopurine: is there diurnal variation in the disposition of antileukemic therapy? Am J Pediatr Hematol Oncol. 1989; 11(3):324-6.
Score: 0.068
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Pharmacokinetics of subcutaneous methotrexate. J Clin Oncol. 1988 Dec; 6(12):1882-6.
Score: 0.068
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The effect of methotrexate on the bioavailability of oral 6-mercaptopurine. Clin Pharmacol Ther. 1987 Apr; 41(4):384-7.
Score: 0.060
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Folate and methotrexate polyglutamate tissue levels in rhesus monkeys following chronic low-dose methotrexate. Cancer Drug Deliv. 1987; 4(1):25-31.
Score: 0.059
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Very high-dose methotrexate (33.6 g/m(2)) as central nervous system preventive therapy for childhood acute lymphoblastic leukemia: results of National Cancer Institute/Children's Cancer Group trials CCG-191P, CCG-134P and CCG-144P. Leuk Lymphoma. 2006 Dec; 47(12):2488-504.
Score: 0.059
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The pharmacology of orally administered chemotherapy. A reappraisal. Cancer. 1986 Jul 15; 58(2 Suppl):473-80.
Score: 0.058
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The effect of amitriptyline on the central nervous system penetration of methotrexate. Cancer Drug Deliv. 1986; 3(4):219-22.
Score: 0.055
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The influence of route of administration on the hepatic uptake of methotrexate. Cancer Drug Deliv. 1986; 3(4):239-42.
Score: 0.055
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Remission induction of meningeal leukemia with high-dose intravenous methotrexate. J Clin Oncol. 1985 Apr; 3(4):485-9.
Score: 0.053
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Prevention of methotrexate cytotoxicity by asparaginase inhibition of methotrexate polyglutamate formation. Cancer Res. 1985 Jan; 45(1):217-20.
Score: 0.052
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Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2. J Natl Cancer Inst. 2004 Oct 20; 96(20):1557-9.
Score: 0.051
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Massive intrathecal overdose: "check the label twice!". N Engl J Med. 1984 Aug 09; 311(6):400-2.
Score: 0.050
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Methotrexate levels in the interstitial space and seminiferous tubule of rat testis. Cancer Res. 1982 May; 42(5):1617-9.
Score: 0.043
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Intraventricular versus intralumbar methotrexate for central-nervous-system leukemia: prolonged remission with the Ommaya reservoir. Med Pediatr Oncol. 1979; 6(3):207-13.
Score: 0.034
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Methotrexate-induced oral mucositis and salivary methotrexate concentrations. Cancer Chemother Pharmacol. 1979; 2(3):225-6.
Score: 0.034
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Pharmacokinetics and pharmacodynamics of oral methotrexate and mercaptopurine in children with lower risk acute lymphoblastic leukemia: a joint children's cancer group and pediatric oncology branch study. Blood. 1998 Nov 15; 92(10):3569-77.
Score: 0.034
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A primate model for study of methotrexate pharmacokinetics in the central nervous system. Cancer Res. 1977 Jul; 37(7 Pt 1):1982-5.
Score: 0.031
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Safety and efficacy of l-leucovorin rescue following high-dose methotrexate for osteosarcoma. Med Pediatr Oncol. 1995 Jun; 24(6):362-7.
Score: 0.027
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Characterization of cross-resistance to methotrexate in a human breast cancer cell line selected for resistance to melphalan. Biochem Pharmacol. 1995 Apr 18; 49(8):1069-78.
Score: 0.026
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Effect of body position on ventricular CSF methotrexate concentration following intralumbar administration. J Clin Oncol. 1995 Jan; 13(1):177-9.
Score: 0.026
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Current pharmacological treatment approaches to central nervous system leukaemia. Drugs. 1991 May; 41(5):702-16.
Score: 0.020
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Pharmacologic approaches to the treatment of meningeal malignancy. Oncology (Williston Park). 1991 May; 5(5):107-16; discussion 123, 127.
Score: 0.020
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Phase II trial of sequential methotrexate and 5-fluorouracil with leucovorin in children with sarcomas. Invest New Drugs. 1990 May; 8(2):181-2.
Score: 0.019
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Central nervous system pharmacology of antileukemic drugs. Am J Pediatr Hematol Oncol. 1989; 11(1):74-86.
Score: 0.017
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Mechanism of acquired resistance to methotrexate in P388 murine leukemia cells and in their doxorubicin-resistant subline. Isr J Med Sci. 1988 Sep-Oct; 24(9-10):477-82.
Score: 0.017
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Altered phenytoin clearance during intensive chemotherapy for acute lymphoblastic leukemia. J Pediatr. 1988 Jun; 112(6):996-9.
Score: 0.016
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Transient acute hepatotoxicity of high-dose methotrexate therapy during childhood. NCI Monogr. 1987; (5):207-12.
Score: 0.015
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Pharmacokinetics of trimetrexate (NSC 352122) in monkeys. Cancer Res. 1986 Jan; 46(1):169-74.
Score: 0.014
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Prophylaxis and treatment of leukemia in the central nervous system and other sanctuaries. Semin Oncol. 1985 Jun; 12(2):131-48.
Score: 0.013
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Long-term neuropsychologic sequelae of childhood leukemia: correlation with CT brain scan abnormalities. J Pediatr. 1985 May; 106(5):723-8.
Score: 0.013
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Ascending myelopathy after chemotherapy for central nervous system acute lymphoblastic leukemia: correlation with cerebrospinal fluid myelin basic protein. Med Pediatr Oncol. 1985; 13(1):4-8.
Score: 0.013
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Altered central nervous system pharmacology of methotrexate in childhood leukemia: another sign of meningeal relapse. J Clin Oncol. 1985 Jan; 3(1):19-24.
Score: 0.013
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Probenecid inhibition of methotrexate cytotoxicity in mouse L1210 leukemia cells. Cancer Treat Rep. 1984 Mar; 68(3):521-5.
Score: 0.012
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Reduced pulsatile growth hormone secretion in children after therapy for acute lymphoblastic leukemia. J Pediatr. 1984 Feb; 104(2):182-6.
Score: 0.012
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The effects of prophylactic treatment of the central nervous system on the intellectual functioning of children with acute lymphocytic leukemia. Am J Med. 1981 Jul; 71(1):47-52.
Score: 0.010
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Leukoencephalopathy and elevated levels of myelin basic protein in the cerebrospinal fluid of patients with acute lymphoblastic leukemia. N Engl J Med. 1980 Jul 03; 303(1):19-21.
Score: 0.009
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Active transport of methotrexate from cerebrospinal fluid in humans. Cancer Res. 1980 Jul; 40(7):2184-7.
Score: 0.009
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Intraventricular concentration times time (C x T) methotrexate and cytarabine for patients with recurrent meningeal leukemia and lymphoma. Cancer. 1999 Jan 15; 85(2):511-6.
Score: 0.009
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Experimental approaches to the treatment of CNS leukemia. Am J Pediatr Hematol Oncol. 1979; 1(2):141-9.
Score: 0.009
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Acute encephalopathy after initiation of cranial irradiation for meningeal leukaemia. Lancet. 1978 Jul 01; 2(8079):13-5.
Score: 0.008
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The Ommaya reservoir: newly recognized complications and recommendations for insertion and use. Cancer. 1978 Jun; 41(6):2431-7.
Score: 0.008
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"Concentration x time" methotrexate via a subcutaneous reservoir: a less toxic regimen for intraventricular chemotherapy of central nervous system neoplasms. Blood. 1978 May; 51(5):835-42.
Score: 0.008
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Abnormal CT scans of the brain in asymptomatic children with acute lymphocytic leukemia after prophylactic treatment of the central nervous system with radiation and intrathecal chemotherapy. N Engl J Med. 1978 Apr 13; 298(15):815-8.
Score: 0.008
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Computer assisted tomography in methotrexate encephalopathy. J Comput Assist Tomogr. 1977 Apr; 1(2):216-21.
Score: 0.008
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Reversible dementia temporally associated with intraventricular therapy with methotrexate in a child with acute myelogenous leukemia. J Pediatr. 1976 Jan; 88(1):131-3.
Score: 0.007
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Acute tumor lysis syndrome. A review of 37 patients with Burkitt's lymphoma. Am J Med. 1980 Apr; 68(4):486-91.
Score: 0.002
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Neurotoxicities of current leukemia therapy. Am J Pediatr Hematol Oncol. 1979; 1(2):127-40.
Score: 0.002
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Combined modality treatment of Burkitt's lymphoma. Cancer Treat Rep. 1978 Dec; 62(12):2031-4.
Score: 0.002
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Sequential combination chemotherapy (containing high-dose cyclophosphamide) for metastic osteogenic sarcoma. Cancer Treat Rep. 1978 Feb; 62(2):247-50.
Score: 0.002
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Chronic ventricular cerebrospinal fluid sampling, drug injections, and pressure monitoring using subcutaneous reservoirs in monkeys. Neurosurgery. 1977 Sep-Oct; 1(2):132-5.
Score: 0.002
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Primate model for long-term study of intraventricularly or intrathecally administered drugs and intracranial pressure. Science. 1977 Feb 04; 195(4277):499-501.
Score: 0.002
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Blindness during remission in two patients with acute lymphoblastic leukemia: a possible complication of multimodality therapy. Cancer. 1977 Jan; 39(1):58-61.
Score: 0.002