Connection

DAVID POPLACK to Mercaptopurine

This is a "connection" page, showing publications DAVID POPLACK has written about Mercaptopurine.
Connection Strength

1.266
  1. Desulfuration of 6-mercaptopurine. The basis for the paradoxical cytotoxicity of thiopurines in cultured human leukemic cells. Biochem Pharmacol. 1993 Nov 02; 46(9):1627-36.
    View in: PubMed
    Score: 0.104
  2. A phase II trial of continuous-infusion 6-mercaptopurine for childhood leukemia. Cancer Chemother Pharmacol. 1992; 30(2):155-7.
    View in: PubMed
    Score: 0.092
  3. Intrathecal 6-mercaptopurine: preclinical pharmacology, phase I/II trial, and pharmacokinetic study. Cancer Res. 1991 Nov 15; 51(22):6079-83.
    View in: PubMed
    Score: 0.091
  4. A phase II trial of continuous-infusion 6-mercaptopurine for childhood solid tumors. Cancer Chemother Pharmacol. 1990; 26(5):343-4.
    View in: PubMed
    Score: 0.080
  5. Chronopharmacokinetics of oral methotrexate and 6-mercaptopurine: is there diurnal variation in the disposition of antileukemic therapy? Am J Pediatr Hematol Oncol. 1989; 11(3):324-6.
    View in: PubMed
    Score: 0.075
  6. Bioavailability of low-dose vs high-dose 6-mercaptopurine. Clin Pharmacol Ther. 1988 May; 43(5):588-91.
    View in: PubMed
    Score: 0.071
  7. The effect of methotrexate on the bioavailability of oral 6-mercaptopurine. Clin Pharmacol Ther. 1987 Apr; 41(4):384-7.
    View in: PubMed
    Score: 0.066
  8. Modulation of thiopurine cytotoxicity in the HL-60 cell line by physiological concentrations of hypoxanthine. Cancer Res. 1986 Dec; 46(12 Pt 1):6286-9.
    View in: PubMed
    Score: 0.065
  9. The pharmacology of orally administered chemotherapy. A reappraisal. Cancer. 1986 Jul 15; 58(2 Suppl):473-80.
    View in: PubMed
    Score: 0.063
  10. Biochemical parameters of mercaptopurine activity in patients with acute lymphoblastic leukemia. Cancer Res. 1986 Mar; 46(3):1495-8.
    View in: PubMed
    Score: 0.061
  11. Cellular pharmacokinetics of mercaptopurine in human neoplastic cells and cell lines. Cancer Res. 1985 Sep; 45(9):4156-61.
    View in: PubMed
    Score: 0.059
  12. Kinetic model for disposition of 6-mercaptopurine in monkey plasma and cerebrospinal fluid. Am J Physiol. 1985 Feb; 248(2 Pt 2):R147-56.
    View in: PubMed
    Score: 0.057
  13. Identification of 6-mercaptopurine riboside in patients receiving 6-mercaptopurine as a prolonged intravenous infusion. Biochem Pharmacol. 1984 Dec 15; 33(24):4089-92.
    View in: PubMed
    Score: 0.056
  14. Inhibition of first-pass metabolism in cancer chemotherapy: interaction of 6-mercaptopurine and allopurinol. Clin Pharmacol Ther. 1983 Dec; 34(6):810-7.
    View in: PubMed
    Score: 0.052
  15. Variable bioavailability of oral mercaptopurine. Is maintenance chemotherapy in acute lymphoblastic leukemia being optimally delivered? N Engl J Med. 1983 Apr 28; 308(17):1005-9.
    View in: PubMed
    Score: 0.050
  16. Pharmacokinetics of 6-mercaptopurine (6MP) in the monkey. I. Disposition from plasma and cerebrospinal fluid following iv bolus. Drug Metab Dispos. 1983 Jan-Feb; 11(1):5-9.
    View in: PubMed
    Score: 0.049
  17. Pharmacokinetics and pharmacodynamics of oral methotrexate and mercaptopurine in children with lower risk acute lymphoblastic leukemia: a joint children's cancer group and pediatric oncology branch study. Blood. 1998 Nov 15; 92(10):3569-77.
    View in: PubMed
    Score: 0.037
  18. The cytotoxicity of thioguanine vs mercaptopurine in acute lymphoblastic leukemia. Leuk Res. 1994 Nov; 18(11):805-10.
    View in: PubMed
    Score: 0.028
  19. Pharmacologic approaches to the treatment of meningeal malignancy. Oncology (Williston Park). 1991 May; 5(5):107-16; discussion 123, 127.
    View in: PubMed
    Score: 0.022
  20. Pharmacokinetics of mercaptopurine in children with acute lymphocytic leukemia. N Engl J Med. 1990 Nov 29; 323(22):1565-6.
    View in: PubMed
    Score: 0.021
  21. Central nervous system pharmacology of antileukemic drugs. Am J Pediatr Hematol Oncol. 1989; 11(1):74-86.
    View in: PubMed
    Score: 0.019
  22. Altered phenytoin clearance during intensive chemotherapy for acute lymphoblastic leukemia. J Pediatr. 1988 Jun; 112(6):996-9.
    View in: PubMed
    Score: 0.018
  23. Influence of food intake on bioavailability of oral 6-mercaptopurine in children with acute lymphoblastic leukemia. Pediatr Hematol Oncol. 1986; 3(4):319-24.
    View in: PubMed
    Score: 0.015
  24. Long-term neuropsychologic sequelae of childhood leukemia: correlation with CT brain scan abnormalities. J Pediatr. 1985 May; 106(5):723-8.
    View in: PubMed
    Score: 0.014
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.