Header Logo

Connection

BHAGAVATULA MOORTHY to Humans

Back to Details
This is a "connection" page, showing publications BHAGAVATULA MOORTHY has written about Humans.
BHAGAVATULA MOORTHY
Connection Strength
0.481
Humans
  1. Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Induced Carcinogenesis and Tumorigenesis by Omega-3 Fatty Acids in Mice In Vivo. Int J Mol Sci. 2024 Mar 28; 25(7).
    View in: PubMed
    Score: 0.025
  2. Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1. Free Radic Biol Med. 2024 02 01; 211:35-46.
    View in: PubMed
    Score: 0.025
  3. Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation. Redox Biol. 2023 08; 64:102790.
    View in: PubMed
    Score: 0.024
  4. The Aryl Hydrocarbon Receptor (AHR): A Novel Therapeutic Target for Pulmonary Diseases? Int J Mol Sci. 2022 Jan 28; 23(3).
    View in: PubMed
    Score: 0.022
  5. Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells. Oxid Med Cell Longev. 2021; 2021:5544600.
    View in: PubMed
    Score: 0.021
  6. Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer. Semin Cancer Biol. 2021 11; 76:3-16.
    View in: PubMed
    Score: 0.021
  7. The role of cytochrome P450 (CYP) enzymes in hyperoxic lung injury. Expert Opin Drug Metab Toxicol. 2021 Feb; 17(2):171-178.
    View in: PubMed
    Score: 0.020
  8. Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2. Toxicol Sci. 2020 10 01; 177(2):347-361.
    View in: PubMed
    Score: 0.020
  9. Oxygen-mediated lung injury in mice lacking the gene for NRF2: Rescue with the cytochrome P4501A-inducer, beta-naphthoflavone (BNF), and differential sex-specific effects. Free Radic Biol Med. 2020 11 20; 160:208-218.
    View in: PubMed
    Score: 0.020
  10. Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts from Superfund sites in Harris County, and increased risk of preterm birth (PTB). Biochem Biophys Res Commun. 2019 08 20; 516(2):344-349.
    View in: PubMed
    Score: 0.018
  11. Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: A novel target for prevention of hyperoxic lung injury. Biochem Biophys Res Commun. 2016 08 05; 476(4):346-351.
    View in: PubMed
    Score: 0.015
  12. Gene Expression Profiling Identifies Cell Proliferation and Inflammation as the Predominant Pathways Regulated by Aryl Hydrocarbon Receptor in Primary Human Fetal Lung Cells Exposed to Hyperoxia. Toxicol Sci. 2016 07; 152(1):155-68.
    View in: PubMed
    Score: 0.015
  13. In Vitro Approaches to Study Regulation of Hepatic Cytochrome P450 (CYP) 3A Expression by Paclitaxel and Rifampicin. Methods Mol Biol. 2016; 1395:55-68.
    View in: PubMed
    Score: 0.014
  14. Can maternal DHA supplementation offer long-term protection against neonatal hyperoxic lung injury? Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15; 309(12):L1383-6.
    View in: PubMed
    Score: 0.014
  15. Omeprazole Attenuates Pulmonary Aryl Hydrocarbon Receptor Activation and Potentiates Hyperoxia-Induced Developmental Lung Injury in Newborn Mice. Toxicol Sci. 2015 Nov; 148(1):276-87.
    View in: PubMed
    Score: 0.014
  16. Polycyclic aromatic hydrocarbons: from metabolism to lung cancer. Toxicol Sci. 2015 May; 145(1):5-15.
    View in: PubMed
    Score: 0.014
  17. Sex-specific differences in hyperoxic lung injury in mice: implications for acute and chronic lung disease in humans. Toxicol Appl Pharmacol. 2013 Oct 15; 272(2):281-90.
    View in: PubMed
    Score: 0.012
  18. Prenatal administration of the cytochrome P4501A inducer, ?-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants. Toxicol Appl Pharmacol. 2011 Oct 15; 256(2):83-94.
    View in: PubMed
    Score: 0.010
  19. Augmented oxygen-mediated transcriptional activation of cytochrome P450 (CYP)1A expression and increased susceptibilities to hyperoxic lung injury in transgenic mice carrying the human CYP1A1 or mouse 1A2 promoter in vivo. Biochem Biophys Res Commun. 2011 Apr 01; 407(1):79-85.
    View in: PubMed
    Score: 0.010
  20. Role of retinoic acid in the modulation of benzo(a)pyrene-DNA adducts in human hepatoma cells: implications for cancer prevention. Toxicol Appl Pharmacol. 2010 Dec 15; 249(3):224-30.
    View in: PubMed
    Score: 0.010
  21. Disruption of the gene for CYP1A2, which is expressed primarily in liver, leads to differential regulation of hepatic and pulmonary mouse CYP1A1 expression and augmented human CYP1A1 transcriptional activation in response to 3-methylcholanthrene in vivo. J Pharmacol Exp Ther. 2010 Nov; 335(2):369-79.
    View in: PubMed
    Score: 0.010
  22. Persistent induction of cytochrome P4501A1 in human hepatoma cells by 3-methylcholanthrene: evidence for sustained transcriptional activation of the CYP1A1 promoter. J Pharmacol Exp Ther. 2010 Apr; 333(1):99-109.
    View in: PubMed
    Score: 0.009
  23. Persistent induction of cytochrome P450 (CYP)1A enzymes by 3-methylcholanthrene in vivo in mice is mediated by sustained transcriptional activation of the corresponding promoters. Biochem Biophys Res Commun. 2009 Dec 25; 390(4):1419-24.
    View in: PubMed
    Score: 0.009
  24. Regulation of cytochrome P4501A1 expression by hyperoxia in human lung cell lines: Implications for hyperoxic lung injury. Toxicol Appl Pharmacol. 2008 Dec 01; 233(2):169-78.
    View in: PubMed
    Score: 0.009
  25. 3-Methylcholanthrene elicits DNA adduct formation in the CYP1A1 promoter region and attenuates reporter gene expression in rat H4IIE cells. Biochem Biophys Res Commun. 2007 Mar 23; 354(4):1071-7.
    View in: PubMed
    Score: 0.008
  26. Modulation of pulmonary cytochrome P4501A1 expression by hyperoxia and inhaled nitric oxide in the newborn rat: implications for lung injury. Pediatr Res. 2006 Mar; 59(3):401-6.
    View in: PubMed
    Score: 0.007
  27. Attenuation of hyperoxic lung injury by the CYP1A inducer beta-naphthoflavone. Toxicol Sci. 2005 Sep; 87(1):204-12.
    View in: PubMed
    Score: 0.007
  28. Machine learning-enhanced surface-enhanced spectroscopic detection of polycyclic aromatic hydrocarbons in the human placenta. Proc Natl Acad Sci U S A. 2025 Feb 18; 122(7):e2422537122.
    View in: PubMed
    Score: 0.007
  29. Bioactivation of polycyclic aromatic hydrocarbon carcinogens within the vascular wall: implications for human atherogenesis. Drug Metab Rev. 2005; 37(4):595-610.
    View in: PubMed
    Score: 0.007
  30. Pyro-Catalytic Degradation of Pyrene by Bentonite-Supported Transition Metals: Mechanistic Insights and Trade-Offs with Low Pyrolysis Temperature. Environ Sci Technol. 2023 09 26; 57(38):14373-14383.
    View in: PubMed
    Score: 0.006
  31. Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates. Pediatr Pulmonol. 2023 01; 58(1):271-278.
    View in: PubMed
    Score: 0.006
  32. Effect of sex chromosomes versus hormones in neonatal lung injury. JCI Insight. 2021 07 08; 6(13).
    View in: PubMed
    Score: 0.005
  33. Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and hepatotoxicity. Expert Opin Drug Metab Toxicol. 2020 Nov; 16(11):1109-1124.
    View in: PubMed
    Score: 0.005
  34. Role of c-Jun-N-Terminal Kinase in Pregnane X Receptor-Mediated Induction of Human Cytochrome P4503A4 In Vitro. Drug Metab Dispos. 2018 04; 46(4):397-404.
    View in: PubMed
    Score: 0.004
  35. Newborn Mice Lacking the Gene for Cyp1a1 Are More Susceptible to Oxygen-Mediated Lung Injury, and Are Rescued by Postnatal ?-Naphthoflavone Administration: Implications for Bronchopulmonary Dysplasia in Premature Infants. Toxicol Sci. 2017 05 01; 157(1):260-271.
    View in: PubMed
    Score: 0.004
  36. Involvement of the Bufadienolides in the Detection and Therapy of the Acute Respiratory Distress Syndrome. Lung. 2017 06; 195(3):323-332.
    View in: PubMed
    Score: 0.004
  37. Regulation of drug-metabolizing enzymes in infectious and inflammatory disease: implications for biologics-small molecule drug interactions. Expert Opin Drug Metab Toxicol. 2017 Jun; 13(6):605-616.
    View in: PubMed
    Score: 0.004
  38. Omeprazole induces heme oxygenase-1 in fetal human pulmonary microvascular endothelial cells via hydrogen peroxide-independent Nrf2 signaling pathway. Toxicol Appl Pharmacol. 2016 Nov 15; 311:26-33.
    View in: PubMed
    Score: 0.004
  39. Omeprazole induces NAD(P)H quinone oxidoreductase 1 via aryl hydrocarbon receptor-independent mechanisms: Role of the transcription factor nuclear factor erythroid 2-related factor 2. Biochem Biophys Res Commun. 2015 Nov 13; 467(2):282-7.
    View in: PubMed
    Score: 0.003
  40. Adrenomedullin deficiency potentiates hyperoxic injury in fetal human pulmonary microvascular endothelial cells. Biochem Biophys Res Commun. 2015 Sep 04; 464(4):1048-1053.
    View in: PubMed
    Score: 0.003
  41. Role of GDF15 (growth and differentiation factor 15) in pulmonary oxygen toxicity. Toxicol In Vitro. 2015 Oct; 29(7):1369-76.
    View in: PubMed
    Score: 0.003
  42. Aryl hydrocarbon receptor is necessary to protect fetal human pulmonary microvascular endothelial cells against hyperoxic injury: Mechanistic roles of antioxidant enzymes and RelB. Toxicol Appl Pharmacol. 2015 Jul 15; 286(2):92-101.
    View in: PubMed
    Score: 0.003
  43. Drug disposition in pathophysiological conditions. Curr Drug Metab. 2012 Nov; 13(9):1327-44.
    View in: PubMed
    Score: 0.003
  44. Omeprazole attenuates hyperoxic injury in H441 cells via the aryl hydrocarbon receptor. Free Radic Biol Med. 2011 Nov 15; 51(10):1910-7.
    View in: PubMed
    Score: 0.003
  45. DNA adducts from alkoxyallylbenzene herb and spice constituents in cultured human (HepG2) cells. Environ Mol Mutagen. 2007 Dec; 48(9):715-21.
    View in: PubMed
    Score: 0.002
  46. An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites. J Neurochem. 2007 Aug; 102(3):867-77.
    View in: PubMed
    Score: 0.002
  47. A Cyp1a2-luciferase transgenic CD-1 mouse model: responses to aryl hydrocarbons similar to the humanized AhR mice. Toxicol Sci. 2004 Nov; 82(1):297-307.
    View in: PubMed
    Score: 0.002
  48. Characterization of a major aromatic DNA adduct detected in human breast tissues. Environ Mol Mutagen. 2002; 39(2-3):193-200.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.