DOUGLASBURRINDOUGLAS BURRIN0.000000000000000.000000000000003211BURRIN, DOUGLASNutritional Regulation of Neonatal Gut and Liver Health and Disease
My laboratory has several basic and translational projects designed to establish how nutritional support, enteral versus parenteral, effects gut and liver function and susceptibility to disease in early development. We have used the neonatal piglet to established unique models of parenteral nutrition-associated liver disease (PNALD), necrotizing enterocolitis (NEC) and short-bowel syndrome (SBS) to address clinically-relevant problems in pediatric gastroenterology.
Current projects in the laboratory seek to identify the cellular and molecular mechanism that lead to PNALD and metabolic dysfunction associated with prematurity and neonatal parenteral nutrition (PN) support. Our recent studies show that chronic PN induces hepatic steatosis, cholestasis and insulin resistance in term and premature neonatal piglets. We are currently exploring how specific nutrients in commercial lipid emulsions alter the susceptibility to PNALD. We are exploring how nutrients affect interorgan and local cellular signaling pathways involved in hepatic lipid metabolism and bile acid homeostasis. We are also testing whether the adverse metabolic phenotype induced by PN is programmed and persists beyond the neonatal period and predisposes to adolescent fatty liver disease and type 2 diabetes.
Studies also are aimed at establishing the cellular and physiological functions of glucagon-like peptide 2 (GLP-2), an FDA-approved gut hormone currently in clinical trial for treatment of adult short-bowel syndrome. Past studies in TPN-fed piglets were first to show the trophic and vasoactive actions of GLP-2 in the neonatal gut. We identified the cellular co-localization of the GLP-2 receptor in enteric neurons with neurotransmitters. Current studies are aimed at establishing unique enterally-mediated signaling mechanisms that trigger enteroendocrine cell GLP-2 secretion and GLP-2 receptor function. We are also testing the efficacy of GLP-2 administration for prevention of NEC and treatment of SBS in premature piglet models.
We take an integrative experimental approach dictated by the research question to address relevant functions at the whole animal, tissue, cellular or molecular level. We use sophisticated metabolic, cell biological and molecular approaches, such as stable isotope metabolomics, laser-capture microdissection, gene microarray, and confocal microscopic imaging to identify the cellular localization of specific signals involved in the metabolism, proliferation and survival of relevant cell types, including mucosal epithelial cells and hepatocytes.Professorplugins:FeaturedVideosFeatured Videosplugins:TwitterTwitterprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:overviewoverviewvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson25342047Sangild PT, Ney DM, Sigalet DL, Vegge A, Burrin DAmerican journal of physiology. Gastrointestinal and liver physiologyAnimal models of gastrointestinal and liver diseases. Animal models of infant short bowel syndrome: translational relevance and challenges. Am J Physiol Gastrointest Liver Physiol. 2014 Dec 15; 307(12):G1147-68.Am J Physiol Gastrointest Liver Physiol2014-10-23T00:00:002014Animal models of gastrointestinal and liver diseases. Animal models of infant short bowel syndrome: translational relevance and challenges.Authorship 803164Authorship 861142Authorship 85327Authorship 855571Authorship 865314Authorship 867622Authorship 90190121779306Davis TA, Suryawan A, Orellana RA, Fiorotto ML, Burrin DGAnimal : an international journal of animal bioscienceAmino acids and insulin are regulators of muscle protein synthesis in neonatal pigs. Animal. 2010; 4(11):1790-1796.Animal2010-01-01T00:00:002010Amino acids and insulin are regulators of muscle protein synthesis in neonatal pigs.Authorship 923553Authorship 936971Authorship 1072486Authorship 112179Authorship 1131758Authorship 1147624Authorship 1214687Authorship 12651Authorship 155764Authorship 164121Authorship 218213Authorship 224512Authorship 162579825649660Jain AK, Wen JX, Arora S, Blomenkamp KS, Rodrigues J, Blaufuss TA, Liou V, Burrin DG, Long JP, Teckman JHNutrition research (New York, N.Y.)Validating hyperbilirubinemia and gut mucosal atrophy with a novel ultramobile ambulatory total parenteral nutrition piglet model. Nutr Res. 2015 Feb; 35(2):169-74.Nutr Res2014-12-31T00:00:002014Validating hyperbilirubinemia and gut mucosal atrophy with a novel ultramobile ambulatory total parenteral nutrition piglet model.Authorship 279892Authorship 28082Authorship 359982Authorship 399584Authorship 461188Authorship 468353Authorship 498806Authorship 517373Authorship 544928Authorship 605352Authorship 626278Authorship 634061Authorship 644963Authorship 718491Authorship 728852Authorship 734341Authorship 793381Authorship 802411Authorship 803472Authorship 83641Authorship 893982Authorship 912752Authorship 937807Authorship 972463Authorship 972906Authorship 977603Authorship 9865717929333Sivakumar B, Jahoor F, Burrin DG, Frazer EM, Reeds PJThe Journal of biological chemistryFractional synthesis rates of retinol-binding protein, transthyretin, and a new peptide measured by stable isotope techniques in neonatal pigs. J Biol Chem. 1994 Oct 21; 269(42):26196-200.J Biol Chem1994-10-21T00:00:001994Fractional synthesis rates of retinol-binding protein, transthyretin, and a new peptide measured by stable isotope techniques in neonatal pigs.7933437Burrin DG, Shulman RJ, Langston C, Storm MCJPEN. Journal of parenteral and enteral nutritionSupplemental alanylglutamine, organ growth, and nitrogen metabolism in neonatal pigs fed by total parenteral nutrition. JPEN J Parenter Enteral Nutr. 1994 Jul-Aug; 18(4):313-9.JPEN J Parenter Enteral Nutr1994-07-01T00:00:001994Supplemental alanylglutamine, organ growth, and nitrogen metabolism in neonatal pigs fed by total parenteral nutrition.8024022Ebner S, Schoknecht P, Reeds P, Burrin DThe American journal of physiologyGrowth and metabolism of gastrointestinal and skeletal muscle tissues in protein-malnourished neonatal pigs. Am J Physiol. 1994 Jun; 266(6 Pt 2):R1736-43.Am J Physiol1994-06-01T00:00:001994Growth and metabolism of gastrointestinal and skeletal muscle tissues in protein-malnourished neonatal pigs.8618147Wykes LJ, Fiorotto M, Burrin DG, Del Rosario M, Frazer ME, Pond WG, Jahoor FThe Journal of nutritionChronic low protein intake reduces tissue protein synthesis in a pig model of protein malnutrition. J Nutr. 1996 May; 126(5):1481-8.J Nutr1996-05-01T00:00:001996Chronic low protein intake reduces tissue protein synthesis in a pig model of protein malnutrition.8618148Jahoor F, Bhattiprolu S, Del Rosario M, Burrin D, Wykes L, Frazer MThe Journal of nutritionChronic protein deficiency differentially affects the kinetics of plasma proteins in young pigs. J Nutr. 1996 May; 126(5):1489-95.J Nutr1996-05-01T00:00:001996Chronic protein deficiency differentially affects the kinetics of plasma proteins in young pigs.8558314Pond WG, Ellis KJ, Mersmann HJ, Heath JP, Krook LP, Burrin DG, Dudley MA, Sheng HPThe Journal of nutritionSevere protein deficiency and repletion alter body and brain composition and organ weights in infant pigs. J Nutr. 1996 Jan; 126(1):290-302.J Nutr1996-01-01T00:00:001996Severe protein deficiency and repletion alter body and brain composition and organ weights in infant pigs.7603776Burrin DG, Davis TA, Ebner S, Schoknecht PA, Fiorotto ML, Reeds PJ, McAvoy SPediatric researchNutrient-independent and nutrient-dependent factors stimulate protein synthesis in colostrum-fed newborn pigs. Pediatr Res. 1995 May; 37(5):593-9.Pediatr Res1995-05-01T00:00:001995Nutrient-independent and nutrient-dependent factors stimulate protein synthesis in colostrum-fed newborn pigs.8798249Burrin DG, Wang H, Heath J, Dudley MAPediatric researchOrally administered lactoferrin increases hepatic protein synthesis in formula-fed newborn pigs. Pediatr Res. 1996 Jul; 40(1):72-6.Pediatr Res1996-07-01T00:00:001996Orally administered lactoferrin increases hepatic protein synthesis in formula-fed newborn pigs.8928910Burrin DG, Wester TJ, Davis TA, Amick S, Heath JPThe American journal of physiologyOrally administered IGF-I increases intestinal mucosal growth in formula-fed neonatal pigs. Am J Physiol. 1996 May; 270(5 Pt 2):R1085-91.Am J Physiol1996-05-01T00:00:001996Orally administered IGF-I increases intestinal mucosal growth in formula-fed neonatal pigs.9003357Dudley MA, Burrin DG, Quaroni A, Rosenberger J, Cook G, Nichols BL, Reeds PJThe Biochemical journalLactase phlorhizin hydrolase turnover in vivo in water-fed and colostrum-fed newborn pigs. Biochem J. 1996 Dec 15; 320 ( Pt 3):735-43.Biochem J1996-12-15T00:00:001996Lactase phlorhizin hydrolase turnover in vivo in water-fed and colostrum-fed newborn pigs.8967468Davis TA, Burrin DG, Fiorotto ML, Nguyen HVThe American journal of physiologyProtein synthesis in skeletal muscle and jejunum is more responsive to feeding in 7-than in 26-day-old pigs. Am J Physiol. 1996 May; 270(5 Pt 1):E802-9.Am J Physiol1996-05-01T00:00:001996Protein synthesis in skeletal muscle and jejunum is more responsive to feeding in 7-than in 26-day-old pigs.9331878Burrin DG, Davis TA, Fiorotto ML, Reeds PJJournal of animal scienceRole of milk-borne vs endogenous insulin-like growth factor I in neonatal growth. J Anim Sci. 1997 Oct; 75(10):2739-43.J Anim Sci1997-10-01T00:00:001997Role of milk-borne vs endogenous insulin-like growth factor I in neonatal growth.8048626Jahoor F, Burrin DG, Reeds PJ, Frazer MThe American journal of physiologyMeasurement of plasma protein synthesis rate in infant pig: an investigation of alternative tracer approaches. Am J Physiol. 1994 Jul; 267(1 Pt 2):R221-7.Am J Physiol1994-07-01T00:00:001994Measurement of plasma protein synthesis rate in infant pig: an investigation of alternative tracer approaches.9435545Stoll B, Burrin DG, Henry J, Jahoor F, Reeds PJThe American journal of physiologyPhenylalanine utilization by the gut and liver measured with intravenous and intragastric tracers in pigs. Am J Physiol. 1997 12; 273(6):G1208-17.Am J Physiol1997-12-01T00:00:001997Phenylalanine utilization by the gut and liver measured with intravenous and intragastric tracers in pigs.9176189Davis TA, Fiorotto ML, Burrin DG, Pond WG, Nguyen HVThe American journal of physiologyIntrauterine growth restriction does not alter response of protein synthesis to feeding in newborn pigs. Am J Physiol. 1997 May; 272(5 Pt 1):E877-84.Am J Physiol1997-05-01T00:00:001997Intrauterine growth restriction does not alter response of protein synthesis to feeding in newborn pigs.9478022Davis TA, Burrin DG, Fiorotto ML, Reeds PJ, Jahoor FThe Journal of nutritionRoles of insulin and amino acids in the regulation of protein synthesis in the neonate. J Nutr. 1998 02; 128(2 Suppl):347S-350S.J Nutr1998-02-01T00:00:001998Roles of insulin and amino acids in the regulation of protein synthesis in the neonate.9482771Stoll B, Henry J, Reeds PJ, Yu H, Jahoor F, Burrin DGThe Journal of nutritionCatabolism dominates the first-pass intestinal metabolism of dietary essential amino acids in milk protein-fed piglets. J Nutr. 1998 Mar; 128(3):606-14.J Nutr1998-03-01T00:00:001998Catabolism dominates the first-pass intestinal metabolism of dietary essential amino acids in milk protein-fed piglets.9266216Reeds PJ, Berthold HK, Boza JJ, Burrin DG, Jahoor F, Jaksic T, Klein PD, Keshen T, Miller R, Stoll B, Wykes LJEuropean journal of pediatricsIntegration of amino acid and carbon intermediary metabolism: studies with uniformly labeled tracers and mass isotopomer analysis. Eur J Pediatr. 1997 Aug; 156 Suppl 1:S50-8.Eur J Pediatr1997-08-01T00:00:001997Integration of amino acid and carbon intermediary metabolism: studies with uniformly labeled tracers and mass isotopomer analysis.9277395Reeds PJ, Burrin DG, Stoll B, Jahoor F, Wykes L, Henry J, Frazer METhe American journal of physiologyEnteral glutamate is the preferential source for mucosal glutathione synthesis in fed piglets. Am J Physiol. 1997 Aug; 273(2 Pt 1):E408-15.Am J Physiol1997-08-01T00:00:001997Enteral glutamate is the preferential source for mucosal glutathione synthesis in fed piglets.1374754Burrin DG, Britton RA, Ferrell CL, Bauer MLJournal of animal scienceLevel of nutrition and visceral organ protein synthetic capacity and nucleic acid content in sheep. J Anim Sci. 1992 Apr; 70(4):1137-45.J Anim Sci1992-04-01T00:00:001992Level of nutrition and visceral organ protein synthetic capacity and nucleic acid content in sheep.9458782Dudley MA, Wykes LJ, Dudley AW, Burrin DG, Nichols BL, Rosenberger J, Jahoor F, Heird WC, Reeds PJThe American journal of physiologyParenteral nutrition selectively decreases protein synthesis in the small intestine. Am J Physiol. 1998 01; 274(1):G131-7.Am J Physiol1998-01-01T00:00:001998Parenteral nutrition selectively decreases protein synthesis in the small intestine.8493277Reeds PJ, Burrin DG, Davis TA, Fiorotto MLThe Proceedings of the Nutrition SocietyPostnatal growth of gut and muscle: competitors or collaborators. Proc Nutr Soc. 1993 Feb; 52(1):57-67.Proc Nutr Soc1993-02-01T00:00:001993Postnatal growth of gut and muscle: competitors or collaborators.10749770Lewis AJ, Wester TJ, Burrin DG, Dauncey MJAmerican journal of physiology. Regulatory, integrative and comparative physiologyExogenous growth hormone induces somatotrophic gene expression in neonatal liver and skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2000 Apr; 278(4):R838-44.Am J Physiol Regul Integr Comp Physiol2000-04-01T00:00:002000Exogenous growth hormone induces somatotrophic gene expression in neonatal liver and skeletal muscle.10828178Reeds PJ, Burrin DG, Davis TA, Fiorotto ML, Stoll B, van Goudoever JBThe Proceedings of the Nutrition SocietyProtein nutrition of the neonate. Proc Nutr Soc. 2000 Feb; 59(1):87-97.Proc Nutr Soc2000-02-01T00:00:002000Protein nutrition of the neonate.Authorship 3053606Authorship 305846726061399Zamora IJ, Stoll B, Ethun CG, Sheikh F, Yu L, Burrin DG, Brandt ML, Olutoye OOPloS oneLow Abdominal NIRS Values and Elevated Plasma Intestinal Fatty Acid-Binding Protein in a Premature Piglet Model of Necrotizing Enterocolitis. PLoS One. 2015; 10(6):e0125437.PLoS One2015-06-10T00:00:002015Low Abdominal NIRS Values and Elevated Plasma Intestinal Fatty Acid-Binding Protein in a Premature Piglet Model of Necrotizing Enterocolitis.26138468Shen RL, Thymann T, ?stergaard MV, St?y AC, Krych L, Nielsen DS, Lauridsen C, Hartmann B, Holst JJ, Burrin DG, Sangild PTAmerican journal of physiology. Gastrointestinal and liver physiologyEarly gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 01; 309(5):G310-23.Am J Physiol Gastrointest Liver Physiol2015-07-02T00:00:002015Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs.9915875Burrin DG, Fiorotto ML, Hadsell DLThe Journal of nutritionTransgenic hypersecretion of des(1-3) human insulin-like growth factor I in mouse milk has limited effects on the gastrointestinal tract in suckling pups. J Nutr. 1999 Jan; 129(1):51-6.J Nutr1999-01-01T00:00:001999Transgenic hypersecretion of des(1-3) human insulin-like growth factor I in mouse milk has limited effects on the gastrointestinal tract in suckling pups.11287360Davis TA, Fiorotto ML, Beckett PR, Burrin DG, Reeds PJ, Wray-Cahen D, Nguyen HVAmerican journal of physiology. Endocrinology and metabolismDifferential effects of insulin on peripheral and visceral tissue protein synthesis in neonatal pigs. Am J Physiol Endocrinol Metab. 2001 May; 280(5):E770-9.Am J Physiol Endocrinol Metab2001-05-01T00:00:002001Differential effects of insulin on peripheral and visceral tissue protein synthesis in neonatal pigs.9164987Dudley MA, Wykes L, Dudley AW, Fiorotto M, Burrin DG, Rosenberger J, Jahoor F, Reeds PJThe Journal of nutritionLactase phlorizin hydrolase synthesis is decreased in protein-malnourished pigs. J Nutr. 1997 May; 127(5):687-93.J Nutr1997-05-01T00:00:001997Lactase phlorizin hydrolase synthesis is decreased in protein-malnourished pigs.12217880Davis TA, Fiorotto ML, Burrin DG, Vann RC, Reeds PJ, Nguyen HV, Beckett PR, Bush JAAmerican journal of physiology. Endocrinology and metabolismAcute IGF-I infusion stimulates protein synthesis in skeletal muscle and other tissues of neonatal pigs. Am J Physiol Endocrinol Metab. 2002 Oct; 283(4):E638-47.Am J Physiol Endocrinol Metab2002-10-01T00:00:002002Acute IGF-I infusion stimulates protein synthesis in skeletal muscle and other tissues of neonatal pigs.9262223Schoknecht PA, Ebner S, Skottner A, Burrin DG, Davis TA, Ellis K, Pond WGPediatric researchExogenous insulin-like growth factor-I increases weight gain in intrauterine growth-retarded neonatal pigs. Pediatr Res. 1997 Aug; 42(2):201-7.Pediatr Res1997-08-01T00:00:001997Exogenous insulin-like growth factor-I increases weight gain in intrauterine growth-retarded neonatal pigs.10837305Burrin DG, Stoll B, Jiang R, Chang X, Hartmann B, Holst JJ, Greeley GH, Reeds PJThe American journal of clinical nutritionMinimal enteral nutrient requirements for intestinal growth in neonatal piglets: how much is enough? Am J Clin Nutr. 2000 Jun; 71(6):1603-10.Am J Clin Nutr2000-06-01T00:00:002000Minimal enteral nutrient requirements for intestinal growth in neonatal piglets: how much is enough?10906591Reeds PJ, Burrin DGNutrition (Burbank, Los Angeles County, Calif.)The gut and amino acid homeostasis. Nutrition. 2000 Jul-Aug; 16(7-8):666-8.Nutrition2000-07-01T00:00:002000The gut and amino acid homeostasis.9530162Dudley MA, Burrin DG, Wykes LJ, Toffolo G, Cobelli C, Nichols BL, Rosenberger J, Jahoor F, Reeds PJThe American journal of physiologyProtein kinetics determined in vivo with a multiple-tracer, single-sample protocol: application to lactase synthesis. Am J Physiol. 1998 03; 274(3):G591-8.Am J Physiol1998-03-01T00:00:001998Protein kinetics determined in vivo with a multiple-tracer, single-sample protocol: application to lactase synthesis.12851176Bos C, Stoll B, Fouillet H, Gaudichon C, Guan X, Grusak MA, Reeds PJ, Tom? D, Burrin DGAmerican journal of physiology. Endocrinology and metabolismIntestinal lysine metabolism is driven by the enteral availability of dietary lysine in piglets fed a bolus meal. Am J Physiol Endocrinol Metab. 2003 Dec; 285(6):E1246-57.Am J Physiol Endocrinol Metab2003-07-08T00:00:002003Intestinal lysine metabolism is driven by the enteral availability of dietary lysine in piglets fed a bolus meal.12851879Guan X, Stoll B, Lu X, Tappenden KA, Holst JJ, Hartmann B, Burrin DGGastroenterologyGLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1. Gastroenterology. 2003 Jul; 125(1):136-47.Gastroenterology2003-07-01T00:00:002003GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1.9732313Stoll B, Burrin DG, Henry J, Yu H, Jahoor F, Reeds PJThe Journal of nutritionDietary amino acids are the preferential source of hepatic protein synthesis in piglets. J Nutr. 1998 Sep; 128(9):1517-24.J Nutr1998-09-01T00:00:001998Dietary amino acids are the preferential source of hepatic protein synthesis in piglets.9755078Wray-Cahen D, Nguyen HV, Burrin DG, Beckett PR, Fiorotto ML, Reeds PJ, Wester TJ, Davis TAThe American journal of physiologyResponse of skeletal muscle protein synthesis to insulin in suckling pigs decreases with development. Am J Physiol. 1998 10; 275(4):E602-9.Am J Physiol1998-10-01T00:00:001998Response of skeletal muscle protein synthesis to insulin in suckling pigs decreases with development.1375287Burrin DG, Shulman RJ, Reeds PJ, Davis TA, Gravitt KRThe Journal of nutritionPorcine colostrum and milk stimulate visceral organ and skeletal muscle protein synthesis in neonatal piglets. J Nutr. 1992 Jun; 122(6):1205-13.J Nutr1992-06-01T00:00:001992Porcine colostrum and milk stimulate visceral organ and skeletal muscle protein synthesis in neonatal piglets.9950786Burrin DG, Wester TJ, Davis TA, Fiorotto ML, Chang XThe American journal of physiologyDexamethasone inhibits small intestinal growth via increased protein catabolism in neonatal pigs. Am J Physiol. 1999 02; 276(2):E269-77.Am J Physiol1999-02-01T00:00:001999Dexamethasone inhibits small intestinal growth via increased protein catabolism in neonatal pigs.10409133Davis TA, Fiorotto ML, Nguyen HV, Burrin DGThe American journal of physiologyAminoacyl-tRNA and tissue free amino acid pools are equilibrated after a flooding dose of phenylalanine. Am J Physiol. 1999 07; 277(1):E103-9.Am J Physiol1999-07-01T00:00:001999Aminoacyl-tRNA and tissue free amino acid pools are equilibrated after a flooding dose of phenylalanine.10409141Stoll B, Burrin DG, Henry J, Yu H, Jahoor F, Reeds PJThe American journal of physiologySubstrate oxidation by the portal drained viscera of fed piglets. Am J Physiol. 1999 07; 277(1):E168-75.Am J Physiol1999-07-01T00:00:001999Substrate oxidation by the portal drained viscera of fed piglets.11739877Jensen AR, Elnif J, Burrin DG, Sangild PTThe Journal of nutritionDevelopment of intestinal immunoglobulin absorption and enzyme activities in neonatal pigs is diet dependent. J Nutr. 2001 Dec; 131(12):3259-65.J Nutr2001-12-01T00:00:002001Development of intestinal immunoglobulin absorption and enzyme activities in neonatal pigs is diet dependent.10613760Jiang R, Chang X, Stoll B, Fan MZ, Arthington J, Weaver E, Campbell J, Burrin DGThe Journal of nutritionDietary plasma protein reduces small intestinal growth and lamina propria cell density in early weaned pigs. J Nutr. 2000 Jan; 130(1):21-6.J Nutr2000-01-01T00:00:002000Dietary plasma protein reduces small intestinal growth and lamina propria cell density in early weaned pigs.15113722van der Schoor SR, Stoll B, Wattimena DL, B?ller HA, Tibboel D, Burrin DG, van Goudoever JBThe American journal of clinical nutritionSplanchnic bed metabolism of glucose in preterm neonates. Am J Clin Nutr. 2004 May; 79(5):831-7.Am J Clin Nutr2004-05-01T00:00:002004Splanchnic bed metabolism of glucose in preterm neonates.11882508Davis TA, Fiorotto ML, Burrin DG, Reeds PJ, Nguyen HV, Beckett PR, Vann RC, O'Connor PMAmerican journal of physiology. Endocrinology and metabolismStimulation of protein synthesis by both insulin and amino acids is unique to skeletal muscle in neonatal pigs. Am J Physiol Endocrinol Metab. 2002 Apr; 282(4):E880-90.Am J Physiol Endocrinol Metab2002-04-01T00:00:002002Stimulation of protein synthesis by both insulin and amino acids is unique to skeletal muscle in neonatal pigs.11917740Burrin DG, Stoll BClinics in perinatologyKey nutrients and growth factors for the neonatal gastrointestinal tract. Clin Perinatol. 2002 Mar; 29(1):65-96.Clin Perinatol2002-03-01T00:00:002002Key nutrients and growth factors for the neonatal gastrointestinal tract.10710502Vann RC, Nguyen HV, Reeds PJ, Burrin DG, Fiorotto ML, Steele NC, Deaver DR, Davis TAAmerican journal of physiology. Endocrinology and metabolismSomatotropin increases protein balance by lowering body protein degradation in fed, growing pigs. Am J Physiol Endocrinol Metab. 2000 Mar; 278(3):E477-83.Am J Physiol Endocrinol Metab2000-03-01T00:00:002000Somatotropin increases protein balance by lowering body protein degradation in fed, growing pigs.15471799Davis TA, Bush JA, Vann RC, Suryawan A, Kimball SR, Burrin DGJournal of animal scienceSomatotropin regulation of protein metabolism in pigs. J Anim Sci. 2004; 82 E-Suppl:E207-213.J Anim Sci2004-01-01T00:00:002004Somatotropin regulation of protein metabolism in pigs.25596209Ng K, Stoll B, Chacko S, Saenz de Pipaon M, Lauridsen C, Gray M, Squires EJ, Marini J, Zamora IJ, Olutoye OO, Burrin DGJPEN. Journal of parenteral and enteral nutritionVitamin E in New-Generation Lipid Emulsions Protects Against Parenteral Nutrition-Associated Liver Disease in Parenteral Nutrition-Fed Preterm Pigs. JPEN J Parenter Enteral Nutr. 2016 07; 40(5):656-71.JPEN J Parenter Enteral Nutr2015-01-16T00:00:002015Vitamin E in New-Generation Lipid Emulsions Protects Against Parenteral Nutrition-Associated Liver Disease in Parenteral Nutrition-Fed Preterm Pigs.1100 BATESHouston, 77030TX11016965van Goudoever JB, Stoll B, Henry JF, Burrin DG, Reeds PJProceedings of the National Academy of Sciences of the United States of AmericaAdaptive regulation of intestinal lysine metabolism. Proc Natl Acad Sci U S A. 2000 Oct 10; 97(21):11620-5.Proc Natl Acad Sci U S A2000-10-10T00:00:002000Adaptive regulation of intestinal lysine metabolism.74Professor10Assistant Professor54Instructor14Associate Professor46Distinguished Emeritus Professor78Professor Emeritus6Adjunct Professor12221228Sangild PT, Petersen YM, Schmidt M, Elnif J, Petersen TK, Buddington RK, Greisen G, Michaelsen KF, Burrin DGThe Journal of nutritionPreterm birth affects the intestinal response to parenteral and enteral nutrition in newborn pigs. J Nutr. 2002 Sep; 132(9):2673-81.J Nutr2002-09-01T00:00:002002Preterm birth affects the intestinal response to parenteral and enteral nutrition in newborn pigs.11238751van Goudoever JB, Stoll B, Hartmann B, Holst JJ, Reeds PJ, Burrin DGThe Journal of nutritionSecretion of trophic gut peptides is not different in bolus- and continuously fed piglets. J Nutr. 2001 Mar; 131(3):729-32.J Nutr2001-03-01T00:00:002001Secretion of trophic gut peptides is not different in bolus- and continuously fed piglets.15795432Schaart MW, Schierbeek H, van der Schoor SR, Stoll B, Burrin DG, Reeds PJ, van Goudoever JBThe Journal of nutritionThreonine utilization is high in the intestine of piglets. J Nutr. 2005 Apr; 135(4):765-70.J Nutr2005-04-01T00:00:002005Threonine utilization is high in the intestine of piglets.12586312Burrin DG, Stoll B, Guan XDomestic animal endocrinologyGlucagon-like peptide 2 function in domestic animals. Domest Anim Endocrinol. 2003 Mar; 24(2):103-22.Domest Anim Endocrinol2003-03-01T00:00:002003Glucagon-like peptide 2 function in domestic animals.12936930Burrin DG, Stoll B, Chang X, Van Goudoever JB, Fujii H, Hutson SM, Reeds PJThe American journal of clinical nutritionParenteral nutrition results in impaired lactose digestion and hexose absorption when enteral feeding is initiated in infant pigs. Am J Clin Nutr. 2003 Sep; 78(3):461-70.Am J Clin Nutr2003-09-01T00:00:002003Parenteral nutrition results in impaired lactose digestion and hexose absorption when enteral feeding is initiated in infant pigs.Authorship 31935911Authorship 3212438Authorship 322140426984322Yang C, Yang X, Lackeyram D, Rideout TC, Wang Z, Stoll B, Yin Y, Burrin DG, Fan MZAmino acidsExpression of apical Na(+)-L-glutamine co-transport activity, B(0)-system neutral amino acid co-transporter (B(0)AT1) and angiotensin-converting enzyme 2 along the jejunal crypt-villus axis in young pigs fed a liquid formula. Amino Acids. 2016 06; 48(6):1491-508.Amino Acids2016-03-16T00:00:002016Expression of apical Na(+)-L-glutamine co-transport activity, B(0)-system neutral amino acid co-transporter (B(0)AT1) and angiotensin-converting enzyme 2 along the jejunal crypt-villus axis in young pigs fed a liquid formula.27218859Yun C, Yin T, Shatzer K, Burrin DG, Cui L, Tu Y, Hu MJournal of chromatography. B, Analytical technologies in the biomedical and life sciencesDetermination of 7a-OH cholesterol by LC-MS/MS: Application in assessing the activity of CYP7A1 in cholestatic minipigs. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jul 01; 1025:76-82.J Chromatogr B Analyt Technol Biomed Life Sci2016-05-09T00:00:002016Determination of 7a-OH cholesterol by LC-MS/MS: Application in assessing the activity of CYP7A1 in cholestatic minipigs.12221235Owens L, Burrin DG, Berseth CLThe Journal of nutritionMinimal enteral feeding induces maturation of intestinal motor function but not mucosal growth in neonatal dogs. J Nutr. 2002 Sep; 132(9):2717-22.J Nutr2002-09-01T00:00:002002Minimal enteral feeding induces maturation of intestinal motor function but not mucosal growth in neonatal dogs.16902328van Goudoever JB, van der Schoor SR, Stoll B, Burrin DG, Wattimena D, Schierbeek H, Schaart MW, Riedijk MA, van der Lugt JNestle Nutrition workshop series. Paediatric programmeIntestinal amino acid metabolism in neonates. Nestle Nutr Workshop Ser Pediatr Program. 2006; 58:95-102; discussion 102-8.Nestle Nutr Workshop Ser Pediatr Program2006-01-01T00:00:002006Intestinal amino acid metabolism in neonates.Authorship 3263601627474222Guthrie G, Kulkarni M, Vlaardingerbroek H, Stoll B, Ng K, Martin C, Belmont J, Hadsell D, Heird W, Newgard CB, Olutoye O, van Goudoever J, Lauridsen C, He X, Schuchman EH, Burrin DJournal of lipid researchMulti-omic profiles of hepatic metabolism in TPN-fed preterm pigs administered new generation lipid emulsions. J Lipid Res. 2016 09; 57(9):1696-711.J Lipid Res2016-07-29T00:00:002016Multi-omic profiles of hepatic metabolism in TPN-fed preterm pigs administered new generation lipid emulsions.15044176Fan MZ, Matthews JC, Etienne NM, Stoll B, Lackeyram D, Burrin DGAmerican journal of physiology. Gastrointestinal and liver physiologyExpression of apical membrane L-glutamate transporters in neonatal porcine epithelial cells along the small intestinal crypt-villus axis. Am J Physiol Gastrointest Liver Physiol. 2004 Aug; 287(2):G385-98.Am J Physiol Gastrointest Liver Physiol2004-03-25T00:00:002004Expression of apical membrane L-glutamate transporters in neonatal porcine epithelial cells along the small intestinal crypt-villus axis.15090907Burrin DG, Davis TACurrent opinion in clinical nutrition and metabolic careProteins and amino acids in enteral nutrition. Curr Opin Clin Nutr Metab Care. 2004 Jan; 7(1):79-87.Curr Opin Clin Nutr Metab Care2004-01-01T00:00:002004Proteins and amino acids in enteral nutrition.2051230Burrin DG, Davis TA, Fiorotto ML, Reeds PJThe Journal of nutritionStage of development and fasting affect protein synthetic activity in the gastrointestinal tissues of suckling rats. J Nutr. 1991 Jul; 121(7):1099-108.J Nutr1991-07-01T00:00:001991Stage of development and fasting affect protein synthetic activity in the gastrointestinal tissues of suckling rats.18296381Burrin DG, Janeczko MJ, Stoll BAsia Pacific journal of clinical nutritionEmerging aspects of dietary glutamate metabolism in the developing gut. Asia Pac J Clin Nutr. 2008; 17 Suppl 1:368-71.Asia Pac J Clin Nutr2008-01-01T00:00:002008Emerging aspects of dietary glutamate metabolism in the developing gut.15465774German JB, Bauman DE, Burrin DG, Failla ML, Freake HC, King JC, Klein S, Milner JA, Pelto GH, Rasmussen KM, Zeisel SHThe Journal of nutritionMetabolomics in the opening decade of the 21st century: building the roads to individualized health. J Nutr. 2004 Oct; 134(10):2729-32.J Nutr2004-10-01T00:00:002004Metabolomics in the opening decade of the 21st century: building the roads to individualized health.14608101Burrin D, Guan X, Stoll B, Petersen YM, Sangild PTThe Journal of nutritionGlucagon-like peptide 2: a key link between nutrition and intestinal adaptation in neonates? J Nutr. 2003 Nov; 133(11):3712-6.J Nutr2003-11-01T00:00:002003Glucagon-like peptide 2: a key link between nutrition and intestinal adaptation in neonates?14720211Sakai R, Cohen DM, Henry JF, Burrin DG, Reeds PJJournal of neurochemistryLeucine-nitrogen metabolism in the brain of conscious rats: its role as a nitrogen carrier in glutamate synthesis in glial and neuronal metabolic compartments. J Neurochem. 2004 Feb; 88(3):612-22.J Neurochem2004-02-01T00:00:002004Leucine-nitrogen metabolism in the brain of conscious rats: its role as a nitrogen carrier in glutamate synthesis in glial and neuronal metabolic compartments.15987836Shoveller AK, Stoll B, Ball RO, Burrin DGThe Journal of nutritionNutritional and functional importance of intestinal sulfur amino acid metabolism. J Nutr. 2005 Jul; 135(7):1609-12.J Nutr2005-07-01T00:00:002005Nutritional and functional importance of intestinal sulfur amino acid metabolism.15173413Niinikoski H, Stoll B, Guan X, Kansagra K, Lambert BD, Stephens J, Hartmann B, Holst JJ, Burrin DGThe Journal of nutritionOnset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets. J Nutr. 2004 Jun; 134(6):1467-74.J Nutr2004-06-01T00:00:002004Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets.20841502Bauchart-Thevret C, Cui L, Wu G, Burrin DGAmerican journal of physiology. Endocrinology and metabolismArginine-induced stimulation of protein synthesis and survival in IPEC-J2 cells is mediated by mTOR but not nitric oxide. Am J Physiol Endocrinol Metab. 2010 Dec; 299(6):E899-909.Am J Physiol Endocrinol Metab2010-09-14T00:00:002010Arginine-induced stimulation of protein synthesis and survival in IPEC-J2 cells is mediated by mTOR but not nitric oxide.15507535Bos C, Stoll B, Fouillet H, Gaudichon C, Guan X, Grusak MA, Reeds PJ, Burrin DG, Tom? DAmerican journal of physiology. Endocrinology and metabolismPostprandial intestinal and whole body nitrogen kinetics and distribution in piglets fed a single meal. Am J Physiol Endocrinol Metab. 2005 Feb; 288(2):E436-46.Am J Physiol Endocrinol Metab2004-10-26T00:00:002004Postprandial intestinal and whole body nitrogen kinetics and distribution in piglets fed a single meal.Authorship 3280721327562956Ettayebi K, Crawford SE, Murakami K, Broughman JR, Karandikar U, Tenge VR, Neill FH, Blutt SE, Zeng XL, Qu L, Kou B, Opekun AR, Burrin D, Graham DY, Ramani S, Atmar RL, Estes MKScience (New York, N.Y.)Replication of human noroviruses in stem cell-derived human enteroids. Science. 2016 09 23; 353(6306):1387-1393.Science2016-08-25T00:00:002016Replication of human noroviruses in stem cell-derived human enteroids.21683194Gay AN, Lazar DA, Stoll B, Naik-Mathuria B, Mushin OP, Rodriguez MA, Burrin DG, Olutoye OOJournal of pediatric surgeryNear-infrared spectroscopy measurement of abdominal tissue oxygenation is a useful indicator of intestinal blood flow and necrotizing enterocolitis in premature piglets. J Pediatr Surg. 2011 Jun; 46(6):1034-40.J Pediatr Surg2011-06-01T00:00:002011Near-infrared spectroscopy measurement of abdominal tissue oxygenation is a useful indicator of intestinal blood flow and necrotizing enterocolitis in premature piglets.16582093Stoll B, Burrin DGJournal of animal scienceMeasuring splanchnic amino acid metabolism in vivo using stable isotopic tracers. J Anim Sci. 2006 Apr; 84 Suppl:E60-72.J Anim Sci2006-04-01T00:00:002006Measuring splanchnic amino acid metabolism in vivo using stable isotopic tracers.Authorship 37486351942471Shulman RJ, Burrin DGJPEN. Journal of parenteral and enteral nutritionTotal parenteral nutrition energy composition affects small intestinal disaccharidase activity in the newborn miniature pig. JPEN J Parenter Enteral Nutr. 1991 Sep-Oct; 15(5):560-3.JPEN J Parenter Enteral Nutr1991-09-01T00:00:001991Total parenteral nutrition energy composition affects small intestinal disaccharidase activity in the newborn miniature pig.16856315Burrin DG, Dudley MA, Reeds PJ, Shulman RJ, Perkinson S, Rosenberger JThe Journal of nutritionFeeding colostrum rapidly alters enzymatic activity and the relative isoform abundance of jejunal lactase in neonatal pigs. J Nutr. 1994 Dec; 124(12):2350-7.J Nutr1994-12-01T00:00:001994Feeding colostrum rapidly alters enzymatic activity and the relative isoform abundance of jejunal lactase in neonatal pigs.16954336Burrin DG, Stoll B, Guan X, Cui L, Chang X, Hadsell DAmerican journal of physiology. Endocrinology and metabolismGLP-2 rapidly activates divergent intracellular signaling pathways involved in intestinal cell survival and proliferation in neonatal piglets. Am J Physiol Endocrinol Metab. 2007 Jan; 292(1):E281-91.Am J Physiol Endocrinol Metab2006-09-05T00:00:002006GLP-2 rapidly activates divergent intracellular signaling pathways involved in intestinal cell survival and proliferation in neonatal piglets.16988124Wang H, Khaoustov VI, Krishnan B, Cai W, Stoll B, Burrin DG, Yoffe BThe Journal of nutritionTotal parenteral nutrition induces liver steatosis and apoptosis in neonatal piglets. J Nutr. 2006 Oct; 136(10):2547-52.J Nutr2006-10-01T00:00:002006Total parenteral nutrition induces liver steatosis and apoptosis in neonatal piglets.16401478Guan X, Karpen HE, Stephens J, Bukowski JT, Niu S, Zhang G, Stoll B, Finegold MJ, Holst JJ, Hadsell D, Hadsell DL, Nichols BL, Burrin DGGastroenterologyGLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow. Gastroenterology. 2006 Jan; 130(1):150-64.Gastroenterology2006-01-01T00:00:002006GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow.17360659Riedijk MA, Stoll B, Chacko S, Schierbeek H, Sunehag AL, van Goudoever JB, Burrin DGProceedings of the National Academy of Sciences of the United States of AmericaMethionine transmethylation and transsulfuration in the piglet gastrointestinal tract. Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9):3408-13.Proc Natl Acad Sci U S A2007-02-21T00:00:002007Methionine transmethylation and transsulfuration in the piglet gastrointestinal tract.2789987Burrin DG, Ferrell CL, Eisemann JH, Britton RA, Nienaber JAThe British journal of nutritionEffect of level of nutrition on splanchnic blood flow and oxygen consumption in sheep. Br J Nutr. 1989 Jul; 62(1):23-34.Br J Nutr1989-07-01T00:00:001989Effect of level of nutrition on splanchnic blood flow and oxygen consumption in sheep.17143057Burrin DG, Stoll BCurrent opinion in clinical nutrition and metabolic careEmerging aspects of gut sulfur amino acid metabolism. Curr Opin Clin Nutr Metab Care. 2007 Jan; 10(1):63-8.Curr Opin Clin Nutr Metab Care2007-01-01T00:00:002007Emerging aspects of gut sulfur amino acid metabolism.17951474Janeczko MJ, Stoll B, Chang X, Guan X, Burrin DGThe Journal of nutritionExtensive gut metabolism limits the intestinal absorption of excessive supplemental dietary glutamate loads in infant pigs. J Nutr. 2007 Nov; 137(11):2384-90.J Nutr2007-11-01T00:00:002007Extensive gut metabolism limits the intestinal absorption of excessive supplemental dietary glutamate loads in infant pigs.17622957Ha?s SP, Ordonez JM, Burrin DG, Sunehag ALPediatric researchDietary glutamate is almost entirely removed in its first pass through the splanchnic bed in premature infants. Pediatr Res. 2007 Sep; 62(3):353-6.Pediatr Res2007-09-01T00:00:002007Dietary glutamate is almost entirely removed in its first pass through the splanchnic bed in premature infants.2058738Fiorotto ML, Burrin DG, Perez M, Reeds PJThe American journal of physiologyIntake and use of milk nutrients by rat pups suckled in small, medium, or large litters. Am J Physiol. 1991 Jun; 260(6 Pt 2):R1104-13.Am J Physiol1991-06-01T00:00:001991Intake and use of milk nutrients by rat pups suckled in small, medium, or large litters.18801965Thivierge MC, Bush JA, Suryawan A, Nguyen HV, Orellana RA, Burrin DG, Jahoor F, Davis TAJournal of applied physiology (Bethesda, Md. : 1985)Positive net movements of amino acids in the hindlimb after overnight food deprivation contribute to sustaining the elevated anabolism of neonatal pigs. J Appl Physiol (1985). 2008 Dec; 105(6):1959-66.J Appl Physiol (1985)2008-09-18T00:00:002008Positive net movements of amino acids in the hindlimb after overnight food deprivation contribute to sustaining the elevated anabolism of neonatal pigs.18806120Bertolo RF, Burrin DGThe Journal of nutritionComparative aspects of tissue glutamine and proline metabolism. J Nutr. 2008 Oct; 138(10):2032S-2039S.J Nutr2008-10-01T00:00:002008Comparative aspects of tissue glutamine and proline metabolism.18818317Bjornvad CR, Thymann T, Deutz NE, Burrin DG, Jensen SK, Jensen BB, M?lbak L, Boye M, Larsson LI, Schmidt M, Michaelsen KF, Sangild PTAmerican journal of physiology. Gastrointestinal and liver physiologyEnteral feeding induces diet-dependent mucosal dysfunction, bacterial proliferation, and necrotizing enterocolitis in preterm pigs on parenteral nutrition. Am J Physiol Gastrointest Liver Physiol. 2008 Nov; 295(5):G1092-103.Am J Physiol Gastrointest Liver Physiol2008-09-25T00:00:002008Enteral feeding induces diet-dependent mucosal dysfunction, bacterial proliferation, and necrotizing enterocolitis in preterm pigs on parenteral nutrition.19293331Bauchart-Thevret C, Stoll B, Chacko S, Burrin DGAmerican journal of physiology. Endocrinology and metabolismSulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs. Am J Physiol Endocrinol Metab. 2009 Jun; 296(6):E1239-50.Am J Physiol Endocrinol Metab2009-03-17T00:00:002009Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs.19587091Burrin DG, Stoll BThe American journal of clinical nutritionMetabolic fate and function of dietary glutamate in the gut. Am J Clin Nutr. 2009 Sep; 90(3):850S-856S.Am J Clin Nutr2009-07-08T00:00:002009Metabolic fate and function of dietary glutamate in the gut.19724018Verbruggen S, Sy J, Gordon WE, Hsu J, Wu M, Chacko S, Zurakowski D, Burrin D, Castillo LAmerican journal of physiology. Endocrinology and metabolismOntogeny of methionine utilization and splanchnic uptake in critically ill children. Am J Physiol Endocrinol Metab. 2009 Nov; 297(5):E1046-55.Am J Physiol Endocrinol Metab2009-09-01T00:00:002009Ontogeny of methionine utilization and splanchnic uptake in critically ill children.Authorship 654880319808655Thymann T, M?ller HK, Stoll B, St?y AC, Buddington RK, Bering SB, Jensen BB, Olutoye OO, Siggers RH, M?lbak L, Sangild PT, Burrin DGAmerican journal of physiology. Gastrointestinal and liver physiologyCarbohydrate maldigestion induces necrotizing enterocolitis in preterm pigs. Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6):G1115-25.Am J Physiol Gastrointest Liver Physiol2009-10-01T00:00:002009Carbohydrate maldigestion induces necrotizing enterocolitis in preterm pigs.19835653Bauchart-Thevret C, Stoll B, Burrin DGNutrition research reviewsIntestinal metabolism of sulfur amino acids. Nutr Res Rev. 2009 Dec; 22(2):175-87.Nutr Res Rev2009-12-01T00:00:002009Intestinal metabolism of sulfur amino acids.28129045Guthrie G, Premkumar M, Burrin DGNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral NutritionEmerging Clinical Benefits of New-Generation Fat Emulsions in Preterm Neonates. Nutr Clin Pract. 2017 Jun; 32(3):326-336.Nutr Clin Pract2017-01-27T00:00:002017Emerging Clinical Benefits of New-Generation Fat Emulsions in Preterm Neonates.20688461Taylor-Edwards CC, Burrin DG, Matthews JC, McLeod KR, Holst JJ, Harmon DLDomestic animal endocrinologyExpression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake. Domest Anim Endocrinol. 2010 Oct; 39(3):181-93.Domest Anim Endocrinol2010-06-25T00:00:002010Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake.21106927Puiman PJ, Stoll B, van Goudoever JB, Burrin DGThe Journal of nutritionEnteral arginine does not increase superior mesenteric arterial blood flow but induces mucosal growth in neonatal pigs. J Nutr. 2011 Jan; 141(1):63-70.J Nutr2010-11-24T00:00:002010Enteral arginine does not increase superior mesenteric arterial blood flow but induces mucosal growth in neonatal pigs.21257057Taylor-Edwards CC, Burrin DG, Holst JJ, McLeod KR, Harmon DLJournal of dairy scienceGlucagon-like peptide-2 (GLP-2) increases small intestinal blood flow and mucosal growth in ruminating calves. J Dairy Sci. 2011 Feb; 94(2):888-98.J Dairy Sci2011-02-01T00:00:002011Glucagon-like peptide-2 (GLP-2) increases small intestinal blood flow and mucosal growth in ruminating calves.21596995Benight NM, Stoll B, Chacko S, da Silva VR, Marini JC, Gregory JF, Stabler SP, Burrin DGAmerican journal of physiology. Gastrointestinal and liver physiologyB-vitamin deficiency is protective against DSS-induced colitis in mice. Am J Physiol Gastrointest Liver Physiol. 2011 Aug; 301(2):G249-59.Am J Physiol Gastrointest Liver Physiol2011-05-19T00:00:002011B-vitamin deficiency is protective against DSS-induced colitis in mice.2463344Burrin DG, Britton RA, Ferrell CLThe Journal of nutritionVisceral organ size and hepatocyte metabolic activity in fed and fasted rats. J Nutr. 1988 Dec; 118(12):1547-52.J Nutr1988-12-01T00:00:001988Visceral organ size and hepatocyte metabolic activity in fed and fasted rats.20980637Stoll B, Horst DA, Cui L, Chang X, Ellis KJ, Hadsell DL, Suryawan A, Kurundkar A, Maheshwari A, Davis TA, Burrin DGThe Journal of nutritionChronic parenteral nutrition induces hepatic inflammation, steatosis, and insulin resistance in neonatal pigs. J Nutr. 2010 Dec; 140(12):2193-200.J Nutr2010-10-27T00:00:002010Chronic parenteral nutrition induces hepatic inflammation, steatosis, and insulin resistance in neonatal pigs.22556140Benight NM, Stoll B, Marini JC, Burrin DGAmerican journal of physiology. Gastrointestinal and liver physiologyPreventative oral methylthioadenosine is anti-inflammatory and reduces DSS-induced colitis in mice. Am J Physiol Gastrointest Liver Physiol. 2012 Jul; 303(1):G71-82.Am J Physiol Gastrointest Liver Physiol2012-05-03T00:00:002012Preventative oral methylthioadenosine is anti-inflammatory and reduces DSS-induced colitis in mice.21593357Puiman PJ, Jensen M, Stoll B, Renes IB, de Bruijn AC, Dorst K, Schierbeek H, Schmidt M, Boehm G, Burrin DG, Sangild PT, van Goudoever JBThe Journal of nutritionIntestinal threonine utilization for protein and mucin synthesis is decreased in formula-fed preterm pigs. J Nutr. 2011 Jul; 141(7):1306-11.J Nutr2011-05-18T00:00:002011Intestinal threonine utilization for protein and mucin synthesis is decreased in formula-fed preterm pigs.23074237Marini JC, Stoll B, Didelija IC, Burrin DGAmerican journal of physiology. Endocrinology and metabolismDe novo synthesis is the main source of ornithine for citrulline production in neonatal pigs. Am J Physiol Endocrinol Metab. 2012 Dec 01; 303(11):E1348-53.Am J Physiol Endocrinol Metab2012-10-16T00:00:002012De novo synthesis is the main source of ornithine for citrulline production in neonatal pigs.21676273Cilieborg MS, Schmidt M, Skovgaard K, Boye M, Weber NR, Heegaard PM, Burrin DG, Sangild PTThe British journal of nutritionFetal lipopolysaccharide exposure modulates diet-dependent gut maturation and sensitivity to necrotising enterocolitis in pre-term pigs. Br J Nutr. 2011 Sep; 106(6):852-61.Br J Nutr2011-05-17T00:00:002011Fetal lipopolysaccharide exposure modulates diet-dependent gut maturation and sensitivity to necrotising enterocolitis in pre-term pigs.23343934Benight NM, Stoll B, Olutoye OO, Holst JJ, Burrin DGJournal of pediatric gastroenterology and nutritionGLP-2 delays but does not prevent the onset of necrotizing enterocolitis in preterm pigs. J Pediatr Gastroenterol Nutr. 2013 Jun; 56(6):623-30.J Pediatr Gastroenterol Nutr2013-06-01T00:00:002013GLP-2 delays but does not prevent the onset of necrotizing enterocolitis in preterm pigs.23446960Bauchart-Thevret C, Stoll B, Benight NM, Olutoye O, Lazar D, Burrin DGThe Journal of nutritionSupplementing monosodium glutamate to partial enteral nutrition slows gastric emptying in preterm pigs(1-3). J Nutr. 2013 May; 143(5):563-70.J Nutr2013-02-27T00:00:002013Supplementing monosodium glutamate to partial enteral nutrition slows gastric emptying in preterm pigs(1-3).Authorship 841033528267073Nichols BL, Avery SE, Quezada-Calvillo R, Kilani SB, Lin AH, Burrin DG, Hodges BE, Chacko SK, Opekun AR, Hindawy ME, Hamaker BR, Oda SIJournal of pediatric gastroenterology and nutritionImproved Starch Digestion of Sucrase-deficient Shrews Treated With Oral Glucoamylase Enzyme Supplements. J Pediatr Gastroenterol Nutr. 2017 08; 65(2):e35-e42.J Pediatr Gastroenterol Nutr2017-08-01T00:00:002017Improved Starch Digestion of Sucrase-deficient Shrews Treated With Oral Glucoamylase Enzyme Supplements.23031436Taylor-Edwards CC, Burrin DG, Kristensen NB, Holst JJ, McLeod KR, Harmon DLAnimal : an international journal of animal bioscienceGlucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves. Animal. 2012 Dec; 6(12):1985-97.Animal2012-05-09T00:00:002012Glucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves.23729782Burrin D, Stoll B, Moore DJournal of animal scienceDigestive physiology of the pig symposium: intestinal bile acid sensing is linked to key endocrine and metabolic signaling pathways. J Anim Sci. 2013 May; 91(5):1991-2000.J Anim Sci2013-05-01T00:00:002013Digestive physiology of the pig symposium: intestinal bile acid sensing is linked to key endocrine and metabolic signaling pathways.Authorship 868653528344059Jordan K, Pontoppidan P, Uhlving HH, Kielsen K, Burrin DG, Weischendorff S, Christensen IJ, J?rgensen MH, Heilmann C, Sengel?v H, M?ller KBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow TransplantationGastrointestinal Toxicity, Systemic Inflammation, and Liver Biochemistry in Allogeneic Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2017 Jul; 23(7):1170-1176.Biol Blood Marrow Transplant2017-03-23T00:00:002017Gastrointestinal Toxicity, Systemic Inflammation, and Liver Biochemistry in Allogeneic Hematopoietic Stem Cell Transplantation.28385289Martin CR, Stoll B, Cluette-Brown J, Akinkuotu AC, Olutoye OO, Gura KM, Singh P, Zaman MM, Perillo MC, Puder M, Freedman SD, Burrin DNutrition research (New York, N.Y.)Use of a novel docosahexaenoic acid formulation vs control in a neonatal porcine model of short bowel syndrome leads to greater intestinal absorption and higher systemic levels of DHA. Nutr Res. 2017 Mar; 39:51-60.Nutr Res2017-02-04T00:00:002017Use of a novel docosahexaenoic acid formulation vs control in a neonatal porcine model of short bowel syndrome leads to greater intestinal absorption and higher systemic levels of DHA.Authorship 86890512Authorship 869005128404837Burrin DGThe Journal of nutritionPreserving Mother Nature's Best Food for Preterm Infants. J Nutr. 2017 06; 147(6):1023-1024.J Nutr2017-04-12T00:00:002017Preserving Mother Nature's Best Food for Preterm Infants.7810660Dudley MA, Jahoor F, Burrin DG, Reeds PJThe American journal of physiologyBrush-border disaccharidase synthesis in infant pigs measured in vivo with [2H3]leucine. Am J Physiol. 1994 Dec; 267(6 Pt 1):G1128-34.Am J Physiol1994-12-01T00:00:001994Brush-border disaccharidase synthesis in infant pigs measured in vivo with [2H3]leucine.8638686Reeds PJ, Burrin DG, Jahoor F, Wykes L, Henry J, Frazer EMThe American journal of physiologyEnteral glutamate is almost completely metabolized in first pass by the gastrointestinal tract of infant pigs. Am J Physiol. 1996 Mar; 270(3 Pt 1):E413-8.Am J Physiol1996-03-01T00:00:001996Enteral glutamate is almost completely metabolized in first pass by the gastrointestinal tract of infant pigs.9164277Burrin DGThe Journal of nutritionIs milk-borne insulin-like growth factor-I essential for neonatal development? J Nutr. 1997 05; 127(5 Suppl):975S-979S.J Nutr1997-05-01T00:00:001997Is milk-borne insulin-like growth factor-I essential for neonatal development?9202081Burrin DG, Davis TA, Ebner S, Schoknecht PA, Fiorotto ML, Reeds PJThe Journal of nutritionColostrum enhances the nutritional stimulation of vital organ protein synthesis in neonatal pigs. J Nutr. 1997 Jul; 127(7):1284-9.J Nutr1997-07-01T00:00:001997Colostrum enhances the nutritional stimulation of vital organ protein synthesis in neonatal pigs.9458744Wester TJ, Davis TA, Fiorotto ML, Burrin DGThe American journal of physiologyExogenous growth hormone stimulates somatotropic axis function and growth in neonatal pigs. Am J Physiol. 1998 01; 274(1):E29-37.Am J Physiol1998-01-01T00:00:001998Exogenous growth hormone stimulates somatotropic axis function and growth in neonatal pigs.9672716Reeds PJ, Burrin DG, Davis TA, Stoll BArchiv fur TierernahrungAmino acid metabolism and the energetics of growth. Arch Tierernahr. 1998; 51(2-3):187-97.Arch Tierernahr1998-01-01T00:00:001998Amino acid metabolism and the energetics of growth.1373233Burrin DG, Davis TA, Fiorotto ML, Reeds PJPediatric researchHepatic protein synthesis in suckling rats: effects of stage of development and fasting. Pediatr Res. 1992 Mar; 31(3):247-52.Pediatr Res1992-03-01T00:00:001992Hepatic protein synthesis in suckling rats: effects of stage of development and fasting.9886978Stoll B, Burrin DG, Henry JF, Jahoor F, Reeds PJThe American journal of physiologyDietary and systemic phenylalanine utilization for mucosal and hepatic constitutive protein synthesis in pigs. Am J Physiol. 1999 01; 276(1):G49-57.Am J Physiol1999-01-01T00:00:001999Dietary and systemic phenylalanine utilization for mucosal and hepatic constitutive protein synthesis in pigs.9928604Wester TJ, Fiorotto ML, Klindt J, Burrin DGJournal of animal scienceFeeding colostrum increases circulating insulin-like growth factor I in newborn pigs independent of endogenous growth hormone secretion. J Anim Sci. 1998 Dec; 76(12):3003-9.J Anim Sci1998-12-01T00:00:001998Feeding colostrum increases circulating insulin-like growth factor I in newborn pigs independent of endogenous growth hormone secretion.Authorship 872896728611027Marini JC, Agarwal U, Robinson JL, Yuan Y, Didelija IC, Stoll B, Burrin DGAmerican journal of physiology. Endocrinology and metabolismThe intestinal-renal axis for arginine synthesis is present and functional in the neonatal pig. Am J Physiol Endocrinol Metab. 2017 08 01; 313(2):E233-E242.Am J Physiol Endocrinol Metab2017-06-13T00:00:002017The intestinal-renal axis for arginine synthesis is present and functional in the neonatal pig.10736365Reeds PJ, Burrin DG, Stoll B, Jahoor FThe Journal of nutritionIntestinal glutamate metabolism. J Nutr. 2000 04; 130(4S Suppl):978S-82S.J Nutr2000-04-01T00:00:002000Intestinal glutamate metabolism.10915636Stoll B, Chang X, Fan MZ, Reeds PJ, Burrin DGAmerican journal of physiology. Gastrointestinal and liver physiologyEnteral nutrient intake level determines intestinal protein synthesis and accretion rates in neonatal pigs. Am J Physiol Gastrointest Liver Physiol. 2000 Aug; 279(2):G288-94.Am J Physiol Gastrointest Liver Physiol2000-08-01T00:00:002000Enteral nutrient intake level determines intestinal protein synthesis and accretion rates in neonatal pigs.10917918Jiang R, Chang X, Stoll B, Ellis KJ, Shypailo RJ, Weaver E, Campbell J, Burrin DGThe Journal of nutritionDietary plasma protein is used more efficiently than extruded soy protein for lean tissue growth in early-weaned pigs. J Nutr. 2000 Aug; 130(8):2016-9.J Nutr2000-08-01T00:00:002000Dietary plasma protein is used more efficiently than extruded soy protein for lean tissue growth in early-weaned pigs.11004243Fiorotto ML, Davis TA, Reeds PJ, Burrin DGPediatric researchNonnutritive factors in colostrum enhance myofibrillar protein synthesis in the newborn Pig. Pediatr Res. 2000 Oct; 48(4):511-7.Pediatr Res2000-10-01T00:00:002000Nonnutritive factors in colostrum enhance myofibrillar protein synthesis in the newborn Pig.11093948Burrin DG, Stoll B, Jiang R, Petersen Y, Elnif J, Buddington RK, Schmidt M, Holst JJ, Hartmann B, Sangild PTAmerican journal of physiology. Gastrointestinal and liver physiologyGLP-2 stimulates intestinal growth in premature TPN-fed pigs by suppressing proteolysis and apoptosis. Am J Physiol Gastrointest Liver Physiol. 2000 Dec; 279(6):G1249-56.Am J Physiol Gastrointest Liver Physiol2000-12-01T00:00:002000GLP-2 stimulates intestinal growth in premature TPN-fed pigs by suppressing proteolysis and apoptosis.11238747Burrin DG, Petersen Y, Stoll B, Sangild PThe Journal of nutritionGlucagon-like peptide 2: a nutrient-responsive gut growth factor. J Nutr. 2001 Mar; 131(3):709-12.J Nutr2001-03-01T00:00:002001Glucagon-like peptide 2: a nutrient-responsive gut growth factor.11705785Petersen YM, Burrin DG, Sangild PTAmerican journal of physiology. Regulatory, integrative and comparative physiologyGLP-2 has differential effects on small intestine growth and function in fetal and neonatal pigs. Am J Physiol Regul Integr Comp Physiol. 2001 Dec; 281(6):R1986-93.Am J Physiol Regul Integr Comp Physiol2001-12-01T00:00:002001GLP-2 has differential effects on small intestine growth and function in fetal and neonatal pigs.Authorship 103458111678020Burrin DG, Shulman RJ, Storm MC, Reeds PJJPEN. Journal of parenteral and enteral nutritionGlutamine or glutamic acid effects on intestinal growth and disaccharidase activity in infant piglets receiving total parenteral nutrition. JPEN J Parenter Enteral Nutr. 1991 May-Jun; 15(3):262-6.JPEN J Parenter Enteral Nutr1991-05-01T00:00:001991Glutamine or glutamic acid effects on intestinal growth and disaccharidase activity in infant piglets receiving total parenteral nutrition.12969831Kansagra K, Stoll B, Rognerud C, Niinikoski H, Ou CN, Harvey R, Burrin DAmerican journal of physiology. Gastrointestinal and liver physiologyTotal parenteral nutrition adversely affects gut barrier function in neonatal piglets. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 285(6):G1162-70.Am J Physiol Gastrointest Liver Physiol2003-09-11T00:00:002003Total parenteral nutrition adversely affects gut barrier function in neonatal piglets.28792854Guthrie G, Tackett B, Stoll B, Martin C, Olutoye O, Burrin DGJPEN. Journal of parenteral and enteral nutritionPhytosterols Synergize With Endotoxin to Augment Inflammation in Kupffer Cells but Alone Have Limited Direct Effect on Hepatocytes. JPEN J Parenter Enteral Nutr. 2018 01; 42(1):37-48.JPEN J Parenter Enteral Nutr2017-12-11T00:00:002017Phytosterols Synergize With Endotoxin to Augment Inflammation in Kupffer Cells but Alone Have Limited Direct Effect on Hepatocytes.Authorship 8771126Authorship 877161628786308Aunsholt L, Qvist N, Sangild PT, Vegge A, Stoll B, Burrin DG, Jeppesen PB, Eriksen T, Husby S, Thymann TJPEN. Journal of parenteral and enteral nutritionMinimal Enteral Nutrition to Improve Adaptation After Intestinal Resection in Piglets and Infants. JPEN J Parenter Enteral Nutr. 2018 02; 42(2):446-454.JPEN J Parenter Enteral Nutr2017-12-20T00:00:002017Minimal Enteral Nutrition to Improve Adaptation After Intestinal Resection in Piglets and Infants.1721504Davis TA, Fiorotto ML, Nguyen HV, Burrin DG, Reeds PJThe American journal of physiologyResponse of muscle protein synthesis to fasting in suckling and weaned rats. Am J Physiol. 1991 Dec; 261(6 Pt 2):R1373-80.Am J Physiol1991-12-01T00:00:001991Response of muscle protein synthesis to fasting in suckling and weaned rats.15486229Burrin DG, Stoll B, Guan X, Cui L, Chang X, Holst JJEndocrinologyGlucagon-like peptide 2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets. Endocrinology. 2005 Jan; 146(1):22-32.Endocrinology2004-10-14T00:00:002004Glucagon-like peptide 2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets.15930448Thivierge MC, Bush JA, Suryawan A, Nguyen HV, Orellana RA, Burrin DG, Jahoor F, Davis TAThe Journal of nutritionWhole-body and hindlimb protein breakdown are differentially altered by feeding in neonatal piglets. J Nutr. 2005 Jun; 135(6):1430-7.J Nutr2005-06-01T00:00:002005Whole-body and hindlimb protein breakdown are differentially altered by feeding in neonatal piglets.15987837Zeisel SH, Freake HC, Bauman DE, Bier DM, Burrin DG, German JB, Klein S, Marquis GS, Milner JA, Pelto GH, Rasmussen KMThe Journal of nutritionThe nutritional phenotype in the age of metabolomics. J Nutr. 2005 Jul; 135(7):1613-6.J Nutr2005-07-01T00:00:002005The nutritional phenotype in the age of metabolomics.16166200Stephens J, Stoll B, Cottrell J, Chang X, Helmrath M, Burrin DGAmerican journal of physiology. Regulatory, integrative and comparative physiologyGlucagon-like peptide-2 acutely increases proximal small intestinal blood flow in TPN-fed neonatal piglets. Am J Physiol Regul Integr Comp Physiol. 2006 Feb; 290(2):R283-9.Am J Physiol Regul Integr Comp Physiol2005-09-15T00:00:002005Glucagon-like peptide-2 acutely increases proximal small intestinal blood flow in TPN-fed neonatal piglets.16166344Cottrell JJ, Stoll B, Buddington RK, Stephens JE, Cui L, Chang X, Burrin DGAmerican journal of physiology. Gastrointestinal and liver physiologyGlucagon-like peptide-2 protects against TPN-induced intestinal hexose malabsorption in enterally refed piglets. Am J Physiol Gastrointest Liver Physiol. 2006 Feb; 290(2):G293-300.Am J Physiol Gastrointest Liver Physiol2005-09-15T00:00:002005Glucagon-like peptide-2 protects against TPN-induced intestinal hexose malabsorption in enterally refed piglets.16387897Stoll B, Price PT, Reeds PJ, Chang X, Henry JF, van Goudoever JB, Holst JJ, Burrin DGJPEN. Journal of parenteral and enteral nutritionFeeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs. JPEN J Parenter Enteral Nutr. 2006 Jan-Feb; 30(1):32-9.JPEN J Parenter Enteral Nutr2006-01-01T00:00:002006Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs.16697741Sangild PT, Siggers RH, Schmidt M, Elnif J, Bjornvad CR, Thymann T, Grondahl ML, Hansen AK, Jensen SK, Boye M, Moelbak L, Buddington RK, Westr?m BR, Holst JJ, Burrin DGGastroenterologyDiet- and colonization-dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs. Gastroenterology. 2006 May; 130(6):1776-92.Gastroenterology2006-05-01T00:00:002006Diet- and colonization-dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs.16768828Thymann T, Burrin DG, Tappenden KA, Bjornvad CR, Jensen SK, Sangild PTThe British journal of nutritionFormula-feeding reduces lactose digestive capacity in neonatal pigs. Br J Nutr. 2006 Jun; 95(6):1075-81.Br J Nutr2006-06-01T00:00:002006Formula-feeding reduces lactose digestive capacity in neonatal pigs.17056800Lambert BD, Filip R, Stoll B, Junghans P, Derno M, Hennig U, Souffrant WB, Pierzynowski S, Burrin DGThe Journal of nutritionFirst-pass metabolism limits the intestinal absorption of enteral alpha-ketoglutarate in young pigs. J Nutr. 2006 Nov; 136(11):2779-84.J Nutr2006-11-01T00:00:002006First-pass metabolism limits the intestinal absorption of enteral alpha-ketoglutarate in young pigs.Authorship 10391132061240Burrin DG, Ferrell CL, Eisemann JH, Britton RAJournal of animal scienceLevel of nutrition and splanchnic metabolite flux in young lambs. J Anim Sci. 1991 Mar; 69(3):1082-91.J Anim Sci1991-03-01T00:00:001991Level of nutrition and splanchnic metabolite flux in young lambs.2223745Burrin DG, Ferrell CL, Britton RA, Bauer MThe British journal of nutritionLevel of nutrition and visceral organ size and metabolic activity in sheep. Br J Nutr. 1990 Sep; 64(2):439-48.Br J Nutr1990-09-01T00:00:001990Level of nutrition and visceral organ size and metabolic activity in sheep.21030609Yang C, Albin DM, Wang Z, Stoll B, Lackeyram D, Swanson KC, Yin Y, Tappenden KA, Mine Y, Yada RY, Burrin DG, Fan MZAmerican journal of physiology. Gastrointestinal and liver physiologyApical Na+-D-glucose cotransporter 1 (SGLT1) activity and protein abundance are expressed along the jejunal crypt-villus axis in the neonatal pig. Am J Physiol Gastrointest Liver Physiol. 2011 Jan; 300(1):G60-70.Am J Physiol Gastrointest Liver Physiol2010-10-28T00:00:002010Apical Na+-D-glucose cotransporter 1 (SGLT1) activity and protein abundance are expressed along the jejunal crypt-villus axis in the neonatal pig.22094603Jain AK, Stoll B, Burrin DG, Holst JJ, Moore DDAmerican journal of physiology. Gastrointestinal and liver physiologyEnteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs. Am J Physiol Gastrointest Liver Physiol. 2012 Jan 15; 302(2):G218-24.Am J Physiol Gastrointest Liver Physiol2011-11-17T00:00:002011Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs.22549765Stoll B, Puiman PJ, Cui L, Chang X, Benight NM, Bauchart-Thevret C, Hartmann B, Holst JJ, Burrin DGJPEN. Journal of parenteral and enteral nutritionContinuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs. JPEN J Parenter Enteral Nutr. 2012 Sep; 36(5):538-50.JPEN J Parenter Enteral Nutr2012-05-01T00:00:002012Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs.23139222Puiman P, Stoll B, M?lbak L, de Bruijn A, Schierbeek H, Boye M, Boehm G, Renes I, van Goudoever J, Burrin DAmerican journal of physiology. Gastrointestinal and liver physiologyModulation of the gut microbiota with antibiotic treatment suppresses whole body urea production in neonatal pigs. Am J Physiol Gastrointest Liver Physiol. 2013 Feb 01; 304(3):G300-10.Am J Physiol Gastrointest Liver Physiol2012-11-08T00:00:002012Modulation of the gut microbiota with antibiotic treatment suppresses whole body urea production in neonatal pigs.Authorship 8804315Authorship 8814611029107283Shi X, Chacko S, Li F, Li D, Burrin D, Chan L, Guan XMolecular metabolismAcute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity. Mol Metab. 2017 11; 6(11):1350-1359.Mol Metab2017-09-01T00:00:002017Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity.29462356Sun J, Li Y, Nguyen DN, Mortensen MS, van den Akker CHP, Skeath T, Pors SE, Pankratova S, Rudloff S, S?rensen SJ, Burrin DG, Thymann T, Sangild PTThe Journal of nutritionNutrient Fortification of Human Donor Milk Affects Intestinal Function and Protein Metabolism in Preterm Pigs. J Nutr. 2018 03 01; 148(3):336-347.J Nutr2018-03-01T00:00:002018Nutrient Fortification of Human Donor Milk Affects Intestinal Function and Protein Metabolism in Preterm Pigs.true1ProfessorProfessortrue1ProfessorProfessortrue1InstructorInstructortrue1InstructorInstructortrue1InstructorInstructorAuthorship 1017165Authorship 1022313D007413Anatomy35310810.626795Intestinal MucosaD000831Living Beings39313420.710803Animals, NewbornAuthorship 1065541D007422Anatomy3056840.697591Intestines30048597Robinson JL, Smith VA, Stoll B, Agarwal U, Premkumar MH, Lau P, Cruz SM, Manjarin R, Olutoye O, Burrin DG, Marini JCAmerican journal of physiology. Gastrointestinal and liver physiologyPrematurity reduces citrulline-arginine-nitric oxide production and precedes the onset of necrotizing enterocolitis in piglets. Am J Physiol Gastrointest Liver Physiol. 2018 10 01; 315(4):G638-G649.Am J Physiol Gastrointest Liver Physiol2018-07-26T00:00:002018Prematurity reduces citrulline-arginine-nitric oxide production and precedes the onset of necrotizing enterocolitis in piglets.D013552Living Beings41415390.715352SwineAuthorship 92898411Authorship 93548610Authorship 9378115Authorship 93781210Authorship 939210929921329Call L, Stoll B, Oosterloo B, Ajami N, Sheikh F, Wittke A, Waworuntu R, Berg B, Petrosino J, Olutoye O, Burrin DMicrobiomeMetabolomic signatures distinguish the impact of formula carbohydrates on disease outcome in a preterm piglet model of NEC. Microbiome. 2018 06 19; 6(1):111.Microbiome2018-06-19T00:00:002018Metabolomic signatures distinguish the impact of formula carbohydrates on disease outcome in a preterm piglet model of NEC.29992630Sun J, Li Y, Pan X, Nguyen DN, Brunse A, Bojesen AM, Rudloff S, Mortensen MS, Burrin DG, Sangild PTJPEN. Journal of parenteral and enteral nutritionHuman Milk Fortification with Bovine Colostrum Is Superior to Formula-Based Fortifiers to Prevent Gut Dysfunction, Necrotizing Enterocolitis, and Systemic Infection in Preterm Pigs. JPEN J Parenter Enteral Nutr. 2019 02; 43(2):252-262.JPEN J Parenter Enteral Nutr2018-07-10T00:00:002018Human Milk Fortification with Bovine Colostrum Is Superior to Formula-Based Fortifiers to Prevent Gut Dysfunction, Necrotizing Enterocolitis, and Systemic Infection in Preterm Pigs.29901723Wors?e PS, Sangild PT, van Goudoever JB, Koletzko B, van der Beek EM, Abrahamse-Berkeveld M, Burrin DG, van de Heijning BJM, Thymann TThe Journal of nutritionGrowth and Clinical Variables in Nitrogen-Restricted Piglets Fed an Adjusted Essential Amino Acid Mix: Effects of Partially Intact Protein-Based Diets. J Nutr. 2018 07 01; 148(7):1118-1125.J Nutr2018-07-01T00:00:002018Growth and Clinical Variables in Nitrogen-Restricted Piglets Fed an Adjusted Essential Amino Acid Mix: Effects of Partially Intact Protein-Based Diets.29901732Lykke M, Sangild PT, van Goudoever JB, van Harskamp D, Schierbeek H, Koletzko B, van der Beek EM, Abrahamse-Berkeveld M, van de Heijning BJM, Stoll B, Burrin DG, Thymann TThe Journal of nutritionGrowth and Clinical Variables in Nitrogen-Restricted Piglets Fed an Adjusted Essential Amino Acid Mix: Effects of Free Amino Acid-Based Diets. J Nutr. 2018 07 01; 148(7):1109-1117.J Nutr2018-07-01T00:00:002018Growth and Clinical Variables in Nitrogen-Restricted Piglets Fed an Adjusted Essential Amino Acid Mix: Effects of Free Amino Acid-Based Diets.YONGJIEYANGYONGJIE YANG0.000000000000000.000000000000005565YANG, YONGJIEInstructor2023-08-31NIHBURRIN, DOUGLAS G2013-09-18Regulation of Hepatic Metabolic Function by Parenteral NutritionR01DK0946162006-06-30NIHBURRIN, DOUGLAS G1996-12-13MINIMAL ENTERAL NUTRIENT REQUIREMENTS IN NEONATESR01HD0339202023-08-31NIHEL-SERAG, HASHEM B1999-12-01Texas Medical Center Digestive Diseases CenterP30DK056338Principal InvestigatorCo-Principal InvestigatorPrincipal InvestigatorD001647Chemicals & Drugs1192470.837356Bile Acids and SaltsDepartment of PediatricsDepartment of SurgerySurgery-Pediatric Surgery DivPediatrics-NewbornPediatrics-NutritionBaylor College of MedicineAGUSSURYAWANAGUS SURYAWAN0.000000000000000.00000000000000109SURYAWAN, AGUSInstructorTHERESANICKLASTHERESA NICKLAS0.000000000000000.00000000000000136NICKLAS, THERESAProfessor EmeritusLANLANSHENLANLAN SHEN0.000000000000000.000000000000001664SHEN, LANLANProfessorROBERTSHULMANROBERT SHULMAN0.000000000000000.000000000000002845SHULMAN, ROBERTProfessorOLUYINKAOLUTOYEOLUYINKA OLUTOYE29.70731730000000-95.40226450000000301OLUTOYE, OLUYINKAAdjunct ProfessorTERESADAVISTERESA DAVIS0.000000000000000.000000000000003169DAVIS, TERESAProfessor7.652330.00468548678research areas8.873610.017056850coauthor of190.41622.870260similar to11219selected publicationsFAROOKJAHOORFAROOK JAHOOR0.000000000000000.000000000000003365JAHOOR, FAROOKDistinguished Emeritus ProfessorBARBARASTOLLBARBARA STOLL0.000000000000000.000000000000003441STOLL, BARBARAInstructorAMYHAIRN6k44GzVQIn2S8Ho5G4=AMY HAIR0.000000000000000.000000000000004267HAIR, AMYAssociate ProfessorAuthorship 94123215Authorship 942148530864445Lin S, Yang X, Yuan P, Yang J, Wang P, Zhong H, Zhang X, Che L, Feng B, Li J, Zhuo Y, Lin Y, Xu S, Burrin DG, Fang ZJournal of agricultural and food chemistryUndernutrition Shapes the Gut Microbiota and Bile Acid Profile in Association with Altered Gut-Liver FXR Signaling in Weaning Pigs. J Agric Food Chem. 2019 Apr 03; 67(13):3691-3701.J Agric Food Chem2019-03-22T00:00:002019Undernutrition Shapes the Gut Microbiota and Bile Acid Profile in Association with Altered Gut-Liver FXR Signaling in Weaning Pigs.30822462Plat J, Baumgartner S, Vanmierlo T, L?tjohann D, Calkins KL, Burrin DG, Guthrie G, Thijs C, Te Velde AA, Vreugdenhil ACE, Sverdlov R, Garssen J, Wouters K, Trautwein EA, Wolfs TG, van Gorp C, Mulder MT, Riksen NP, Groen AK, Mensink RPProgress in lipid researchPlant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?" Prog Lipid Res. 2019 04; 74:87-102.Prog Lipid Res2019-02-26T00:00:002019Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?"MOHANPAMMIMOHAN PAMMI29.70508570000000-95.40180870000000578PAMMI, MOHANProfessorAuthorship 94337211Authorship 943477530920308Lin S, Stoll B, Robinson J, Pastor JJ, Marini JC, Ipharraguerre IR, Hartmann B, Holst JJ, Cruz S, Lau P, Olutoye O, Fang Z, Burrin DGAmerican journal of physiology. Gastrointestinal and liver physiologyDifferential action of TGR5 agonists on GLP-2 secretion and promotion of intestinal adaptation in a piglet short bowel model. Am J Physiol Gastrointest Liver Physiol. 2019 05 01; 316(5):G641-G652.Am J Physiol Gastrointest Liver Physiol2019-03-28T00:00:002019Differential action of TGR5 agonists on GLP-2 secretion and promotion of intestinal adaptation in a piglet short bowel model.30910606Weischendorff S, Kielsen K, Nederby M, Schmidt L, Burrin D, Heilmann C, Ifversen M, Sengel?v H, M?lgaard C, M?ller KBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow TransplantationReduced Plasma Amino Acid Levels During Allogeneic Hematopoietic Stem Cell Transplantation Are Associated with Systemic Inflammation and Treatment-Related Complications. Biol Blood Marrow Transplant. 2019 07; 25(7):1432-1440.Biol Blood Marrow Transplant2019-03-22T00:00:002019Reduced Plasma Amino Acid Levels During Allogeneic Hematopoietic Stem Cell Transplantation Are Associated with Systemic Inflammation and Treatment-Related Complications.Authorship 944420830963144Welch-Jernigan RJ, Abrahamse E, Stoll B, Smith O, Wierenga PA, van de Heijning BJM, Renes IB, Burrin DGCurrent developments in nutritionPostprandial Amino Acid Kinetics of Milk Protein Mixtures are Affected by Composition, But Not Denaturation, in Neonatal Piglets. Curr Dev Nutr. 2019 Apr; 3(4):nzy102.Curr Dev Nutr2018-12-19T00:00:002018Postprandial Amino Acid Kinetics of Milk Protein Mixtures are Affected by Composition, But Not Denaturation, in Neonatal Piglets.Authorship 94560517Authorship 9459022531021171Wang P, Zhong H, Song Y, Yuan P, Li Y, Lin S, Zhang X, Li J, Che L, Feng B, Lin Y, Xu S, Zhuo Y, Tian G, Chen D, Burrin DG, Fang ZAmerican journal of physiology. Gastrointestinal and liver physiologyTargeted metabolomics analysis of maternal-placental-fetal metabolism in pregnant swine reveals links in fetal bile acid homeostasis and sulfation capacity. Am J Physiol Gastrointest Liver Physiol. 2019 07 01; 317(1):G8-G16.Am J Physiol Gastrointest Liver Physiol2019-04-25T00:00:002019Targeted metabolomics analysis of maternal-placental-fetal metabolism in pregnant swine reveals links in fetal bile acid homeostasis and sulfation capacity.31026499Molina TL, Stoll B, Mohammad M, Mohila CA, Call L, Cui L, Guthrie G, Kunichoff D, Lin S, Welch-Jernigan R, Nielsen J, Premkumar M, Robinson J, Smith V, Teets H, Obelitz-Ryom K, Hagan J, Cruz S, Lau P, Puyau M, Shypailo R, Manjarin R, Butte N, Fang Z, Olutoye O, Thymann T, Sangild P, Burrin DBrain, behavior, and immunityNew generation lipid emulsions increase brain DHA and improve body composition, but not short-term neurodevelopment in parenterally-fed preterm piglets. Brain Behav Immun. 2020 03; 85:46-56.Brain Behav Immun2019-04-24T00:00:002019New generation lipid emulsions increase brain DHA and improve body composition, but not short-term neurodevelopment in parenterally-fed preterm piglets.Authorship 1267299Authorship 12747012Authorship 129016523764891Vegge A, Thymann T, Lund P, Stoll B, Bering SB, Hartmann B, Jelsing J, Qvist N, Burrin DG, Jeppesen PB, Holst JJ, Sangild PTAmerican journal of physiology. Gastrointestinal and liver physiologyGlucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates. Am J Physiol Gastrointest Liver Physiol. 2013 Aug 15; 305(4):G277-85.Am J Physiol Gastrointest Liver Physiol2013-06-13T00:00:002013Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates.23823479Shi X, Zhou F, Li X, Chang B, Li D, Wang Y, Tong Q, Xu Y, Fukuda M, Zhao JJ, Li D, Burrin DG, Chan L, Guan XCell metabolismCentral GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons. Cell Metab. 2013 Jul 02; 18(1):86-98.Cell Metab2013-07-02T00:00:002013Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons.23942716Sangild PT, Thymann T, Schmidt M, Stoll B, Burrin DG, Buddington RKJournal of animal scienceInvited review: the preterm pig as a model in pediatric gastroenterology. J Anim Sci. 2013 Oct; 91(10):4713-29.J Anim Sci2013-08-13T00:00:002013Invited review: the preterm pig as a model in pediatric gastroenterology.Authorship 1117431Authorship 1071702Authorship 9543441331443432Wang P, Song Y, Zhong H, Lin S, Zhang X, Li J, Che L, Feng B, Lin Y, Xu S, Zhuo Y, Burrin DG, Fang ZInternational journal of molecular sciencesTranscriptome Profiling of Placenta through Pregnancy Reveals Dysregulation of Bile Acids Transport and Detoxification Function. Int J Mol Sci. 2019 Aug 22; 20(17).Int J Mol Sci2019-08-22T00:00:002019Transcriptome Profiling of Placenta through Pregnancy Reveals Dysregulation of Bile Acids Transport and Detoxification Function.Authorship 955291931503514Naberhuis JK, Suryawan A, Nguyen HV, Hernandez-Garcia A, Cruz SM, Lau PE, Olutoye OO, Stoll B, Burrin DG, Fiorotto ML, Davis TAAmerican journal of physiology. Endocrinology and metabolismPrematurity blunts the feeding-induced stimulation of translation initiation signaling and protein synthesis in muscle of neonatal piglets. Am J Physiol Endocrinol Metab. 2019 11 01; 317(5):E839-E851.Am J Physiol Endocrinol Metab2019-09-10T00:00:002019Prematurity blunts the feeding-induced stimulation of translation initiation signaling and protein synthesis in muscle of neonatal piglets.Authorship 957044631604032Guthrie G, Stoll B, Chacko S, Lauridsen C, Plat J, Burrin DAmerican journal of physiology. Gastrointestinal and liver physiologyRifampicin, not vitamin E, suppresses parenteral nutrition-associated liver disease development through the pregnane X receptor pathway in piglets. Am J Physiol Gastrointest Liver Physiol. 2020 01 01; 318(1):G41-G52.Am J Physiol Gastrointest Liver Physiol2019-10-11T00:00:002019Rifampicin, not vitamin E, suppresses parenteral nutrition-associated liver disease development through the pregnane X receptor pathway in piglets.Authorship 1084317true1Adjunct ProfessorAdjunct ProfessorCAITLINVONDEROHECAITLIN VONDEROHE15144VONDEROHE, CAITLINInstructor31760772Mohammad MA, Didelija IC, Wang X, Stoll B, Burrin DG, Marini JCAmerican journal of physiology. Renal physiologyDevelopmental changes in the utilization of citrulline by neonatal pigs. Am J Physiol Renal Physiol. 2020 01 01; 318(1):F175-F182.Am J Physiol Renal Physiol2019-11-25T00:00:002019Developmental changes in the utilization of citrulline by neonatal pigs.Authorship 109183232069436Burrin D, Sangild PT, Stoll B, Thymann T, Buddington R, Marini J, Olutoye O, Shulman RJAnnual review of animal biosciencesTranslational Advances in Pediatric Nutrition and Gastroenterology: New Insights from Pig Models. Annu Rev Anim Biosci. 2020 02 15; 8:321-354.Annu Rev Anim Biosci2020-02-15T00:00:002020Translational Advances in Pediatric Nutrition and Gastroenterology: New Insights from Pig Models.true1ProfessorProfessorAuthorship 9844465Authorship 9846225Authorship 9846627Authorship 98467221Authorship 9850739Authorship 985074132003601Hernandez GV, Smith VA, Melnyk M, Burd MA, Sprayberry KA, Edwards MS, Peterson DG, Bennet DC, Fanter RK, Columbus DA, Steibel JP, Glanz H, Immoos C, Rice MS, Santiago-Rodriguez TM, Blank J, VanderKelen JJ, Kitts CL, Piccolo BD, La Frano MR, Burrin DG, Maj M, Manjarin RAmerican journal of physiology. Gastrointestinal and liver physiologyDysregulated FXR-FGF19 signaling and choline metabolism are associated with gut dysbiosis and hyperplasia in a novel pig model of pediatric NASH. Am J Physiol Gastrointest Liver Physiol. 2020 03 01; 318(3):G582-G609.Am J Physiol Gastrointest Liver Physiol2020-01-31T00:00:002020Dysregulated FXR-FGF19 signaling and choline metabolism are associated with gut dysbiosis and hyperplasia in a novel pig model of pediatric NASH.32069355Ahnfeldt AM, B?k O, Hui Y, Nielsen CH, Obelitz-Ryom K, Busk-Anderson T, Ruge A, Holst JJ, Rudloff S, Burrin D, Nguyen DN, Nielsen DS, Zachariassen G, Bering SB, Thymann T, Sangild PTThe Journal of nutritionNutrient Restriction has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs. J Nutr. 2020 05 01; 150(5):1196-1207.J Nutr2020-05-01T00:00:002020Nutrient Restriction has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs.31990866Smith V, Jiang Y, Thymann T, Sangild P, Maj M, Manjarin R, Burrin DJournal of pediatric gastroenterology and nutritionRapid Postnatal Upregulation of Intestinal Farnesoid X Receptor-Fibroblast Growth Factor 19 Signaling in Premature Pigs. J Pediatr Gastroenterol Nutr. 2020 05; 70(5):e94-e99.J Pediatr Gastroenterol Nutr2020-05-01T00:00:002020Rapid Postnatal Upregulation of Intestinal Farnesoid X Receptor-Fibroblast Growth Factor 19 Signaling in Premature Pigs.31963562Nielsen CH, Hui Y, Nguyen DN, Ahnfeldt AM, Burrin DG, Hartmann B, Heckmann AB, Sangild PT, Thymann T, Bering SBNutrientsAlpha-Lactalbumin Enriched Whey Protein Concentrate to Improve Gut, Immunity and Brain Development in Preterm Pigs. Nutrients. 2020 Jan 17; 12(1).Nutrients2020-01-17T00:00:002020Alpha-Lactalbumin Enriched Whey Protein Concentrate to Improve Gut, Immunity and Brain Development in Preterm Pigs.Authorship 9883442132350078Call L, Molina T, Stoll B, Guthrie G, Chacko S, Plat J, Robinson J, Lin S, Vonderohe C, Mohammad M, Kunichoff D, Cruz S, Lau P, Premkumar M, Nielsen J, Fang Z, Olutoye O, Thymann T, Britton R, Sangild P, Burrin DJournal of lipid researchParenteral lipids shape gut bile acid pools and microbiota profiles in the prevention of cholestasis in preterm pigs. J Lipid Res. 2020 07; 61(7):1038-1051.J Lipid Res2020-04-29T00:00:002020Parenteral lipids shape gut bile acid pools and microbiota profiles in the prevention of cholestasis in preterm pigs.Authorship 1112833Authorship 1164149Authorship 1137501Authorship 995991932744096Zeltser N, Meyer I, Hernandez GV, Trahan MJ, Fanter RK, Abo-Ismail M, Glanz H, Strand CR, Burrin DG, La Frano MR, Manjar?n R, Maj MAmerican journal of physiology. Endocrinology and metabolismNeurodegeneration in juvenile Iberian pigs with diet-induced nonalcoholic fatty liver disease. Am J Physiol Endocrinol Metab. 2020 09 01; 319(3):E592-E606.Am J Physiol Endocrinol Metab2020-08-03T00:00:002020Neurodegeneration in juvenile Iberian pigs with diet-induced nonalcoholic fatty liver disease.Authorship 1177131http://www.bcm.edu/cnrc/kidsabdominalpainCenter for Pediatric Abdominal Pain ResearchAuthorship 1184446Authorship 1190812Authorship 10049574Authorship 1005678533236951Yakah W, Singh P, Brown J, Stoll B, Burrin D, Premkumar MH, Otu HH, Gu X, Dillon ST, Libermann TA, Freedman SD, Martin CRAmerican journal of physiology. Gastrointestinal and liver physiologyParenteral lipid emulsions induce unique ileal fatty acid and metabolomic profiles but do not increase the risk of necrotizing enterocolitis in preterm pigs. Am J Physiol Gastrointest Liver Physiol. 2021 02 01; 320(2):G227-G239.Am J Physiol Gastrointest Liver Physiol2020-11-25T00:00:002020Parenteral lipid emulsions induce unique ileal fatty acid and metabolomic profiles but do not increase the risk of necrotizing enterocolitis in preterm pigs.33181004Mohammad MA, Didelija IC, Stoll B, Burrin DG, Marini JCPhysiological reportsModeling age-dependent developmental changes in the expression of genes involved in citrulline synthesis using pig enteroids. Physiol Rep. 2020 11; 8(21):e14565.Physiol Rep2020-11-01T00:00:002020Modeling age-dependent developmental changes in the expression of genes involved in citrulline synthesis using pig enteroids.Authorship 10086859Authorship 1008840833427053Rudar M, Naberhuis JK, Suryawan A, Nguyen HV, Stoll B, Style CC, Verla MA, Olutoye OO, Burrin DG, Fiorotto ML, Davis TAAmerican journal of physiology. Endocrinology and metabolismPrematurity blunts the insulin- and amino acid-induced stimulation of translation initiation and protein synthesis in skeletal muscle of neonatal pigs. Am J Physiol Endocrinol Metab. 2021 03 01; 320(3):E551-E565.Am J Physiol Endocrinol Metab2021-01-11T00:00:002021Prematurity blunts the insulin- and amino acid-induced stimulation of translation initiation and protein synthesis in skeletal muscle of neonatal pigs.33445698Yakah W, Ramiro-Cortijo D, Singh P, Brown J, Stoll B, Kulkarni M, Oosterloo BC, Burrin D, Maddipati KR, Fichorova RN, Freedman SD, Martin CRNutrientsParenteral Fish-Oil Containing Lipid Emulsions Limit Initial Lipopolysaccharide-Induced Host Immune Responses in Preterm Pigs. Nutrients. 2021 Jan 12; 13(1).Nutrients2021-01-12T00:00:002021Parenteral Fish-Oil Containing Lipid Emulsions Limit Initial Lipopolysaccharide-Induced Host Immune Responses in Preterm Pigs.Authorship 1010013933504663Ettayebi K, Tenge VR, Cortes-Penfield NW, Crawford SE, Neill FH, Zeng XL, Yu X, Ayyar BV, Burrin D, Ramani S, Atmar RL, Estes MKmSphereNew Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids. mSphere. 2021 01 27; 6(1).mSphere2021-01-27T00:00:002021New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids.Authorship 1010943233557154Guthrie G, Burrin DNutrientsImpact of Parenteral Lipid Emulsion Components on Cholestatic Liver Disease in Neonates. Nutrients. 2021 Feb 04; 13(2).Nutrients2021-02-04T00:00:002021Impact of Parenteral Lipid Emulsion Components on Cholestatic Liver Disease in Neonates.Authorship 1202824Authorship 10114811133581699Guthrie G, Stoll B, Chacko S, Mohammad M, Style C, Verla M, Olutoye O, Schady D, Lauridsen C, Tataryn N, Burrin DJPEN. Journal of parenteral and enteral nutritionDepletion and enrichment of phytosterols in soybean oil lipid emulsions directly associate with serum markers of cholestasis in preterm parenteral nutrition-fed pigs. JPEN J Parenter Enteral Nutr. 2022 01; 46(1):160-171.JPEN J Parenter Enteral Nutr2021-04-30T00:00:002021Depletion and enrichment of phytosterols in soybean oil lipid emulsions directly associate with serum markers of cholestasis in preterm parenteral nutrition-fed pigs.Authorship 10135521033693900Maj M, Harbottle B, Thomas PA, Hernandez GV, Smith VA, Edwards MS, Fanter RK, Glanz HS, Immoos C, Burrin DG, Santiago-Rodriguez TM, La Frano MR, Manjar?n RThe Journal of nutritionConsumption of High-Fructose Corn Syrup Compared with Sucrose Promotes Adiposity and Increased Triglyceridemia but Comparable NAFLD Severity in Juvenile Iberian Pigs. J Nutr. 2021 05 11; 151(5):1139-1149.J Nutr2021-05-11T00:00:002021Consumption of High-Fructose Corn Syrup Compared with Sucrose Promotes Adiposity and Increased Triglyceridemia but Comparable NAFLD Severity in Juvenile Iberian Pigs.true1ProfessorProfessorAuthorship 1028470434444709Sangild PT, Vonderohe C, Melendez Hebib V, Burrin DGNutrientsPotential Benefits of Bovine Colostrum in Pediatric Nutrition and Health. Nutrients. 2021 Jul 26; 13(8).Nutrients2021-07-26T00:00:002021Potential Benefits of Bovine Colostrum in Pediatric Nutrition and Health.Authorship 1033480934719946Rudar M, Naberhuis JK, Suryawan A, Nguyen HV, Stoll B, Style CC, Verla MA, Olutoye OO, Burrin DG, Fiorotto ML, Davis TAAmerican journal of physiology. Endocrinology and metabolismIntermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model. Am J Physiol Endocrinol Metab. 2021 12 01; 321(6):E737-E752.Am J Physiol Endocrinol Metab2021-11-01T00:00:002021Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model.Authorship 1034665634851728Vonderohe C, Guthrie G, Stoll B, Chacko S, Dawson H, Burrin DGAmerican journal of physiology. Gastrointestinal and liver physiologyTissue-specific mechanisms of bile acid homeostasis and activation of FXR-FGF19 signaling in preterm and term neonatal pigs. Am J Physiol Gastrointest Liver Physiol. 2022 01 01; 322(1):G117-G133.Am J Physiol Gastrointest Liver Physiol2021-12-01T00:00:002021Tissue-specific mechanisms of bile acid homeostasis and activation of FXR-FGF19 signaling in preterm and term neonatal pigs.Authorship 1036183934959747Spooner HC, Derrick SA, Maj M, Manjar?n R, Hernandez GV, Tailor DS, Bastani PS, Fanter RK, Fiorotto ML, Burrin DG, La Frano MR, Sikalidis AK, Blank JMNutrientsHigh-Fructose, High-Fat Diet Alters Muscle Composition and Fuel Utilization in a Juvenile Iberian Pig Model of Non-Alcoholic Fatty Liver Disease. Nutrients. 2021 Nov 23; 13(12).Nutrients2021-11-23T00:00:002021High-Fructose, High-Fat Diet Alters Muscle Composition and Fuel Utilization in a Juvenile Iberian Pig Model of Non-Alcoholic Fatty Liver Disease.Authorship 1191952true1Associate ProfessorAssociate ProfessorAuthorship 1038515335301051Guthrie G, Vonderohe C, Burrin DMolecular and cellular endocrinologyFibroblast growth factor 15/19 expression, regulation, and function: An overview. Mol Cell Endocrinol. 2022 05 15; 548:111617.Mol Cell Endocrinol2022-03-15T00:00:002022Fibroblast growth factor 15/19 expression, regulation, and function: An overview.Authorship 1378325Authorship 137908924047704Ipharraguerre IR, Ted? G, Menoyo D, de Diego Cabero N, Holst JJ, Nofrar?as M, Mereu A, Burrin DGThe Journal of nutritionBile acids induce glucagon-like peptide 2 secretion with limited effects on intestinal adaptation in early weaned pigs. J Nutr. 2013 Dec; 143(12):1899-905.J Nutr2013-09-18T00:00:002013Bile acids induce glucagon-like peptide 2 secretion with limited effects on intestinal adaptation in early weaned pigs.24157972Jensen ML, Thymann T, Cilieborg MS, Lykke M, M?lbak L, Jensen BB, Schmidt M, Kelly D, Mulder I, Burrin DG, Sangild PTAmerican journal of physiology. Gastrointestinal and liver physiologyAntibiotics modulate intestinal immunity and prevent necrotizing enterocolitis in preterm neonatal piglets. Am J Physiol Gastrointest Liver Physiol. 2014 Jan 01; 306(1):G59-71.Am J Physiol Gastrointest Liver Physiol2013-10-24T00:00:002013Antibiotics modulate intestinal immunity and prevent necrotizing enterocolitis in preterm neonatal piglets.true1Assistant ProfessorAssistant ProfessorTwitter Tweets Harvard Tweets Covid 19 in the neonatal intensive care unitAuthorship 15476Authorship 10486101335742938Wang P, Yuan P, Lin S, Zhong H, Zhang X, Zhuo Y, Li J, Che L, Feng B, Lin Y, Xu S, Burrin DG, Fang ZInternational journal of molecular sciencesMaternal and Fetal Bile Acid Homeostasis Regulated by Sulfated Progesterone Metabolites through FXR Signaling Pathway in a Pregnant Sow Model. Int J Mol Sci. 2022 Jun 10; 23(12).Int J Mol Sci2022-06-10T00:00:002022Maternal and Fetal Bile Acid Homeostasis Regulated by Sulfated Progesterone Metabolites through FXR Signaling Pathway in a Pregnant Sow Model.true1InstructorInstructorAuthorship 1050553735822260Henriksen NL, Hansen SH, Lycas MD, Pan X, Eriksen T, Johansen LS, Sprenger RR, Ejsing CS, Burrin DG, Skovgaard K, Christensen VB, Thymann T, Pankratova SPhysiological reportsCholestasis alters brain lipid and bile acid composition and compromises motor function in neonatal piglets. Physiol Rep. 2022 07; 10(13):e15368.Physiol Rep2022-07-01T00:00:002022Cholestasis alters brain lipid and bile acid composition and compromises motor function in neonatal piglets.Authorship 10508451635858244Manjar?n R, Dillard K, Coffin M, Hernandez GV, Smith VA, Noland-Lidell T, Gehani TR, Smart HJ, Wheeler K, Sprayberry KA, Edwards MS, Fanter RK, Glanz H, Immoos C, Santiago-Rodriguez TM, Blank JM, Burrin DG, Piccolo BD, Abo-Ismail M, La Frano MR, Maj MAmerican journal of physiology. Endocrinology and metabolismDietary fat composition shapes bile acid metabolism and severity of liver injury in a pig model of pediatric NAFLD. Am J Physiol Endocrinol Metab. 2022 09 01; 323(3):E187-E206.Am J Physiol Endocrinol Metab2022-07-20T00:00:002022Dietary fat composition shapes bile acid metabolism and severity of liver injury in a pig model of pediatric NAFLD.true1ProfessorProfessorAuthorship 1198693Authorship 1209954Authorship 120305536128996Rudar M, Suryawan A, Nguyen HV, Chacko SK, Vonderohe C, Stoll B, Burrin DG, Fiorotto ML, Davis TAJPEN. Journal of parenteral and enteral nutritionRegulation of skeletal muscle protein synthesis in the preterm pig by intermittent leucine pulses during continuous parenteral feeding. JPEN J Parenter Enteral Nutr. 2023 02; 47(2):276-286.JPEN J Parenter Enteral Nutr2022-10-10T00:00:002022Regulation of skeletal muscle protein synthesis in the preterm pig by intermittent leucine pulses during continuous parenteral feeding.Authorship 1220366Authorship 122121Authorship 1221271Authorship 10610317Authorship 10546523Authorship 105565612Authorship 10592464Authorship 1054914636367732Vonderohe C, Guthrie G, Stoll B, Hebib VM, Dawson H, Burrin DEndocrinologyIncreased Circulating Cortisol After Vaginal Birth Is Associated With Increased FGF19 Secretion in Neonatal Pigs. Endocrinology. 2022 11 14; 164(1).Endocrinology2022-11-14T00:00:002022Increased Circulating Cortisol After Vaginal Birth Is Associated With Increased FGF19 Secretion in Neonatal Pigs.36648144Vonderohe C, Guthrie G, Burrin DGAmerican journal of physiology. Gastrointestinal and liver physiologyFibroblast growth factor 19 secretion and function in perinatal development. Am J Physiol Gastrointest Liver Physiol. 2023 03 01; 324(3):G190-G195.Am J Physiol Gastrointest Liver Physiol2023-01-17T00:00:002023Fibroblast growth factor 19 secretion and function in perinatal development.35989990Holgersen K, Rasmussen MB, Carey G, Burrin DG, Thymann T, Sangild PTFrontiers in pediatricsClinical outcome and gut development after insulin-like growth factor-1 supplementation to preterm pigs. Front Pediatr. 2022; 10:868911.Front Pediatr2022-08-05T00:00:002022Clinical outcome and gut development after insulin-like growth factor-1 supplementation to preterm pigs.36577494Lin S, Wang S, Wang P, Tang C, Wang Z, Chen L, Luo G, Chen H, Liu Y, Feng B, Burrin DG, Fang ZProgress in lipid researchBile acids and their receptors in regulation of gut health and diseases. Prog Lipid Res. 2023 01; 89:101210.Prog Lipid Res2022-12-25T00:00:002022Bile acids and their receptors in regulation of gut health and diseases.Authorship 1066862736973010Christiansen LI, Holmqvist B, Pan X, Holgersen K, Lindholm SEH, Henriksen NL, Burrin DG, Ley D, Thymann T, Sangild PT, Pankratova SeNeuroInsulin-Like Growth Factor-1 Supplementation Promotes Brain Maturation in Preterm Pigs. eNeuro. 2023 04; 10(4).eNeuro2023-04-14T00:00:002023Insulin-Like Growth Factor-1 Supplementation Promotes Brain Maturation in Preterm Pigs.Authorship 1222626Authorship 10727118Authorship 107321210Authorship 1074556937404461Christiansen LI, Ventura GC, Holmqvist B, Aasmul-Olsen K, Lindholm SEH, Lycas MD, Mori Y, Secher JB, Burrin DG, Thymann T, Sangild PT, Pankratova SFrontiers in neuroscienceInsulin-like growth factor 1 supplementation supports motor coordination and affects myelination in preterm pigs. Front Neurosci. 2023; 17:1205819.Front Neurosci2023-06-19T00:00:002023Insulin-like growth factor 1 supplementation supports motor coordination and affects myelination in preterm pigs.37299550Melendez Hebib V, Taft DH, Stoll B, Liu J, Call L, Guthrie G, Jensen N, Hair AB, Mills DA, Burrin DGNutrientsProbiotics and Human Milk Differentially Influence the Gut Microbiome and NEC Incidence in Preterm Pigs. Nutrients. 2023 May 31; 15(11).Nutrients2023-05-31T00:00:002023Probiotics and Human Milk Differentially Influence the Gut Microbiome and NEC Incidence in Preterm Pigs.37265596Helt TW, Buelund L, Borgwardt L, Eriksen T, Johansen L, de Nijs R, Holm S, Burrin DG, Thymann T, Christensen VBBiochemistry and biophysics reportsTowards a model of biliary atresia - Pilot feasibility study in newborn piglets. Biochem Biophys Rep. 2023 Jul; 34:101487.Biochem Biophys Rep2023-05-23T00:00:002023Towards a model of biliary atresia - Pilot feasibility study in newborn piglets.37666415Moran NE, Wade J, Stroh R, Stoll B, Guthrie G, Hair AB, Burrin DGThe Journal of nutritionPreterm Pigs Fed Donor Human Milk Have Greater Liver ?-Carotene Concentrations than Pigs Fed Infant Formula. J Nutr. 2023 11; 153(11):3185-3192.J Nutr2023-09-04T00:00:002023Preterm Pigs Fed Donor Human Milk Have Greater Liver ?-Carotene Concentrations than Pigs Fed Infant Formula.Authorship 10787067true1Distinguished Emeritus ProfessorDistinguished Emeritus Professortrue1Professor EmeritusProfessor EmeritusAuthorship 204022Authorship 215206Authorship 152211Authorship 10853265Authorship 1085403238086951Rasmussen MB, Holgersen K, Pankratova S, B?k O, Burrin DG, Thymann T, Sangild PTPediatric researchGut development following insulin-like growth factor-1 supplementation to preterm pigs. Pediatr Res. 2023 Dec 12.Pediatr Res2023-12-12T00:00:002023Gut development following insulin-like growth factor-1 supplementation to preterm pigs.38137523Maj MA, Burrin DG, Manjar?n RBiomedicinesDecreased FXR Agonism in the Bile Acid Pool Is Associated with Impaired FXR Signaling in a Pig Model of Pediatric NAFLD. Biomedicines. 2023 Dec 13; 11(12).Biomedicines2023-12-13T00:00:002023Decreased FXR Agonism in the Bile Acid Pool Is Associated with Impaired FXR Signaling in a Pig Model of Pediatric NAFLD.Authorship 1085916738141773Rudar M, Suryawan A, Nguyen HV, Chacko SK, Vonderohe C, Stoll B, Burrin DG, Fiorotto ML, Davis TAThe Journal of nutritionPulsatile Leucine Administration during Continuous Enteral Feeding Enhances Skeletal Muscle Mechanistic Target of Rapamycin Complex 1 Signaling and Protein Synthesis in a Preterm Piglet Model. J Nutr. 2024 02; 154(2):505-515.J Nutr2023-12-22T00:00:002023Pulsatile Leucine Administration during Continuous Enteral Feeding Enhances Skeletal Muscle Mechanistic Target of Rapamycin Complex 1 Signaling and Protein Synthesis in a Preterm Piglet Model.Authorship 10862771838181968Elefson SK, Stoll B, Davis TA, Fiorotto ML, El-Kadi SW, Genovese K, Thymann T, Sangild PT, Burrin DGThe Journal of nutritionAdverse Metabolic Phenotypes in Parenterally Fed Neonatal Pigs Do Not Persist into Adolescence. J Nutr. 2024 02; 154(2):638-647.J Nutr2024-01-03T00:00:002024Adverse Metabolic Phenotypes in Parenterally Fed Neonatal Pigs Do Not Persist into Adolescence.Authorship 245084Authorship 184141Authorship 260031GREGORYGUTHRIEGREGORY GUTHRIE7106GUTHRIE, GREGORYAssistant ProfessorAuthorship 209311Authorship 292652Authorship 307491Authorship 309551Authorship 226744Authorship 323151Authorship 362494Authorship 387471Authorship 391212Authorship 304442Authorship 300964Authorship 1423161Authorship 1427831324425726Burrin DG, Ng K, Stoll B, S?enz De Pipa?n MAdvances in nutrition (Bethesda, Md.)Impact of new-generation lipid emulsions on cellular mechanisms of parenteral nutrition-associated liver disease. Adv Nutr. 2014 Jan 01; 5(1):82-91.Adv Nutr2014-01-01T00:00:002014Impact of new-generation lipid emulsions on cellular mechanisms of parenteral nutrition-associated liver disease.24478031Vlaardingerbroek H, Ng K, Stoll B, Benight N, Chacko S, Kluijtmans LA, Kulik W, Squires EJ, Olutoye O, Schady D, Finegold ML, van Goudoever JB, Burrin DGJournal of lipid researchNew generation lipid emulsions prevent PNALD in chronic parenterally fed preterm pigs. J Lipid Res. 2014 Mar; 55(3):466-77.J Lipid Res2014-01-29T00:00:002014New generation lipid emulsions prevent PNALD in chronic parenterally fed preterm pigs.Authorship 333604Authorship 334615Authorship 335261Authorship 477902Authorship 47856Authorship 360094Authorship 361927Authorship 536461Authorship 363363Authorship 539214Authorship 371308Authorship 407085Authorship 579995Authorship 408489Authorship 1459237Authorship 146741324399211Thymann T, Stoll B, Mecklenburg L, Burrin DG, Vegge A, Qvist N, Eriksen T, Jeppesen PB, Sangild PTJournal of pediatric gastroenterology and nutritionAcute effects of the glucagon-like peptide 2 analogue, teduglutide, on intestinal adaptation in short bowel syndrome. J Pediatr Gastroenterol Nutr. 2014 Jun; 58(6):694-702.J Pediatr Gastroenterol Nutr2014-06-01T00:00:002014Acute effects of the glucagon-like peptide 2 analogue, teduglutide, on intestinal adaptation in short bowel syndrome.24656979Oosterloo BC, Premkumar M, Stoll B, Olutoye O, Thymann T, Sangild PT, Burrin DGVeterinary immunology and immunopathologyDual purpose use of preterm piglets as a model of pediatric GI disease. Vet Immunol Immunopathol. 2014 Jun 15; 159(3-4):156-65.Vet Immunol Immunopathol2014-02-24T00:00:002014Dual purpose use of preterm piglets as a model of pediatric GI disease.Authorship 59809Authorship 439413Authorship 621734Authorship 452215Authorship 466921Authorship 46986Authorship 485084Authorship 674444Authorship 508256Authorship 518807Authorship 739081Authorship 559994Authorship 797202Authorship 80264Authorship 573832Authorship 824033Authorship 83722Authorship 59441Authorship 594724Authorship 599614Authorship 1516481125238061Ghoneim N, Bauchart-Thevret C, Oosterloo B, Stoll B, Kulkarni M, de Pipaon MS, Zamora IJ, Olutoye OO, Berg B, Wittke A, Burrin DGPloS oneDelayed initiation but not gradual advancement of enteral formula feeding reduces the incidence of necrotizing enterocolitis (NEC) in preterm pigs. PLoS One. 2014; 9(9):e106888.PLoS One2014-09-19T00:00:002014Delayed initiation but not gradual advancement of enteral formula feeding reduces the incidence of necrotizing enterocolitis (NEC) in preterm pigs.Authorship 152838325068253Patel AK, Lazar DA, Burrin DG, Smith EO, Magliaro TJ, Stark AR, Brandt ML, Zamora IJ, Sheikh F, Akinkuotu AC, Olutoye OOPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care SocietiesAbdominal near-infrared spectroscopy measurements are lower in preterm infants at risk for necrotizing enterocolitis. Pediatr Crit Care Med. 2014 Oct; 15(8):735-41.Pediatr Crit Care Med2014-10-01T00:00:002014Abdominal near-infrared spectroscopy measurements are lower in preterm infants at risk for necrotizing enterocolitis.Authorship 634439Authorship 667128Authorship 942594Authorship 680055Authorship 687611Authorship 962951Authorship 982402Authorship 70301Authorship 703552Authorship 710026Authorship 713571Authorship 729569Authorship 756081Authorship 1551344