DOROTHYLEWISDOROTHY LEWIS0.000000000000000.000000000000002965LEWIS, DOROTHYAdjunct Professorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 846197Authorship 984654Authorship 1109315Authorship 1143243Authorship 1148387Authorship 1610046Authorship 1620971325589658Budhiraja S, Liu H, Couturier J, Malovannaya A, Qin J, Lewis DE, Rice APJournal of virologyMining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function. J Virol. 2015 Apr; 89(7):3557-67.J Virol2015-01-14T00:00:002015Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function.25849830Couturier J, Suliburk JW, Brown JM, Luke DJ, Agarwal N, Yu X, Nguyen C, Iyer D, Kozinetz CA, Overbeek PA, Metzker ML, Balasubramanyam A, Lewis DEAIDS (London, England)Human adipose tissue as a reservoir for memory CD4+ T cells and HIV. AIDS. 2015 Mar 27; 29(6):667-74.AIDS2015-03-27T00:00:002015Human adipose tissue as a reservoir for memory CD4+ T cells and HIV.Authorship 278816Authorship 299895Veterinary SciencesMD AndersonPRAMOD NNEHETEPRAMOD N NEHETE8630NEHETE, PRAMOD NAssociate ProfessorAuthorship 418833Authorship 4796610Authorship 507604Authorship 585534Authorship 690432Authorship 714962Authorship 2960033Authorship 299726725772268Shiue LH, Couturier J, Lewis DE, Wei C, Ni X, Duvic MPhotodermatology, photoimmunology & photomedicineThe effect of extracorporeal photopheresis alone or in combination therapy on circulating CD4(+) Foxp3(+) CD25(-) T cells in patients with leukemic cutaneous T-cell lymphoma. Photodermatol Photoimmunol Photomed. 2015 Jul; 31(4):184-94.Photodermatol Photoimmunol Photomed2015-03-28T00:00:002015The effect of extracorporeal photopheresis alone or in combination therapy on circulating CD4(+) Foxp3(+) CD25(-) T cells in patients with leukemic cutaneous T-cell lymphoma.26322142Shi C, Li H, Couturier JP, Yang K, Guo X, He D, Lewis DE, Zhou XThe open rheumatology journalAllele Specific Expression of MICA Variants in Human Fibroblasts Suggests a Pathogenic Mechanism. Open Rheumatol J. 2015; 9:60-4.Open Rheumatol J2015-08-26T00:00:002015Allele Specific Expression of MICA Variants in Human Fibroblasts Suggests a Pathogenic Mechanism.12498419Bischoff FZ, Sinacori MK, Dang DD, Marquez-Do D, Horne C, Lewis DE, Simpson JLHuman reproduction updateCell-free fetal DNA and intact fetal cells in maternal blood circulation: implications for first and second trimester non-invasive prenatal diagnosis. Hum Reprod Update. 2002 Nov-Dec; 8(6):493-500.Hum Reprod Update2002-11-01T00:00:002002Cell-free fetal DNA and intact fetal cells in maternal blood circulation: implications for first and second trimester non-invasive prenatal diagnosis.12660526Lednicky JA, Vilchez RA, Keitel WA, Visnegarwala F, White ZS, Kozinetz CA, Lewis DE, Butel JSAIDS (London, England)Polyomavirus JCV excretion and genotype analysis in HIV-infected patients receiving highly active antiretroviral therapy. AIDS. 2003 Apr 11; 17(6):801-7.AIDS2003-04-11T00:00:002003Polyomavirus JCV excretion and genotype analysis in HIV-infected patients receiving highly active antiretroviral therapy.14557970Ling PD, Vilchez RA, Keitel WA, Poston DG, Peng RS, White ZS, Visnegarwala F, Lewis DE, Butel JSClinical infectious diseases : an official publication of the Infectious Diseases Society of AmericaEpstein-Barr virus DNA loads in adult human immunodeficiency virus type 1-infected patients receiving highly active antiretroviral therapy. Clin Infect Dis. 2003 Nov 01; 37(9):1244-9.Clin Infect Dis2003-09-23T00:00:002003Epstein-Barr virus DNA loads in adult human immunodeficiency virus type 1-infected patients receiving highly active antiretroviral therapy.One Baylor PlazaHouston, 77030TX12023371Blutt SE, Warfield KL, Lewis DE, Conner MEJournal of immunology (Baltimore, Md. : 1950)Early response to rotavirus infection involves massive B cell activation. J Immunol. 2002 Jun 01; 168(11):5716-21.J Immunol2002-06-01T00:00:002002Early response to rotavirus infection involves massive B cell activation.12117965Robinson P, White AC, Lewis DE, Thornby J, David E, Weinstock JInfection and immunitySequential expression of the neuropeptides substance P and somatostatin in granulomas associated with murine cysticercosis. Infect Immun. 2002 Aug; 70(8):4534-8.Infect Immun2002-08-01T00:00:002002Sequential expression of the neuropeptides substance P and somatostatin in granulomas associated with murine cysticercosis.74Professor10Assistant Professor14Associate Professor2Adjunct Assistant Professor78Professor Emeritus6Adjunct Professor12854086Robinson P, Okhuysen PC, Chappell CL, Weinstock JV, Lewis DE, Actor JK, White ACThe Journal of infectious diseasesSubstance P expression correlates with severity of diarrhea in cryptosporidiosis. J Infect Dis. 2003 Jul 15; 188(2):290-6.J Infect Dis2003-07-09T00:00:002003Substance P expression correlates with severity of diarrhea in cryptosporidiosis.Authorship 321898827117277Couturier J, Agarwal N, Nehete PN, Baze WB, Barry MA, Jagannadha Sastry K, Balasubramanyam A, Lewis DERetrovirologyInfectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques. Retrovirology. 2016 Apr 27; 13:30.Retrovirology2016-04-27T00:00:002016Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques.16868450Montes M, Lewis DE, Sanchez C, Lopez de Castilla D, Graviss EA, Seas C, Gotuzzo E, White ACAIDS (London, England)Foxp3+ regulatory T cells in antiretroviral-naive HIV patients. AIDS. 2006 Aug 01; 20(12):1669-71.AIDS2006-08-01T00:00:002006Foxp3+ regulatory T cells in antiretroviral-naive HIV patients.17067632Montes M, Jaensson EA, Orozco AF, Lewis DE, Corry DBJournal of immunological methodsA general method for bead-enhanced quantitation by flow cytometry. J Immunol Methods. 2006 Dec 20; 317(1-2):45-55.J Immunol Methods2006-10-10T00:00:002006A general method for bead-enhanced quantitation by flow cytometry.17108192Orozco AF, Bischoff FZ, Horne C, Popek E, Simpson JL, Lewis DEAnnals of the New York Academy of SciencesHypoxia-induced membrane-bound apoptotic DNA particles: potential mechanism of fetal DNA in maternal plasma. Ann N Y Acad Sci. 2006 Sep; 1075:57-62.Ann N Y Acad Sci2006-09-01T00:00:002006Hypoxia-induced membrane-bound apoptotic DNA particles: potential mechanism of fetal DNA in maternal plasma.17171820Corry DB, Lewis DEThe New England journal of medicineCytokine storm and an anti-CD28 monoclonal antibody. N Engl J Med. 2006 Dec 14; 355(24):2592; author reply 2593-4.N Engl J Med2006-12-14T00:00:002006Cytokine storm and an anti-CD28 monoclonal antibody.12531583Bischoff FZ, Hahn S, Johnson KL, Simpson JL, Bianchi DW, Lewis DE, Weber WD, Klinger K, Elias S, Jackson LG, Evans MI, Holzgreve W, de la Cruz FLancet (London, England)Intact fetal cells in maternal plasma: are they really there? Lancet. 2003 Jan 11; 361(9352):139-40.Lancet2003-01-11T00:00:002003Intact fetal cells in maternal plasma: are they really there?15128741Lewis DE, Merched-Sauvage M, Goronzy JJ, Weyand CM, Vallejo ANThe Journal of biological chemistryTumor necrosis factor-alpha and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription. J Biol Chem. 2004 Jul 09; 279(28):29130-8.J Biol Chem2004-05-05T00:00:002004Tumor necrosis factor-alpha and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription.12735873Bischoff FZ, Dang DX, Marquez-Do D, Martinez D, Horne C, Lewis DE, Simpson JLReproductive biomedicine onlineDetecting fetal DNA from dried maternal blood spots: another step towards broad scale non-invasive prenatal genetic screening and feasible testing. Reprod Biomed Online. 2003 Apr-May; 6(3):349-51.Reprod Biomed Online2003-04-01T00:00:002003Detecting fetal DNA from dried maternal blood spots: another step towards broad scale non-invasive prenatal genetic screening and feasible testing.20235276Orozco AF, Lewis DECytometry. Part A : the journal of the International Society for Analytical CytologyFlow cytometric analysis of circulating microparticles in plasma. Cytometry A. 2010 Jun; 77(6):502-14.Cytometry A2010-06-01T00:00:002010Flow cytometric analysis of circulating microparticles in plasma.20348507Pantenburg B, Castellanos-Gonzalez A, Dann SM, Connelly RL, Lewis DE, Ward HD, White ACThe American journal of tropical medicine and hygieneHuman CD8(+) T cells clear Cryptosporidium parvum from infected intestinal epithelial cells. Am J Trop Med Hyg. 2010 Apr; 82(4):600-7.Am J Trop Med Hyg2010-04-01T00:00:002010Human CD8(+) T cells clear Cryptosporidium parvum from infected intestinal epithelial cells.16052094Okhuysen PC, Chappell CL, Lewis DE, Robinson P, White ACAIDS (London, England)Treatment of chronic cryptosporidiosis in AIDS with rIL-12 induces an immune response associated with improvement but severe side-effects. AIDS. 2005 Aug 12; 19(12):1333-4.AIDS2005-08-12T00:00:002005Treatment of chronic cryptosporidiosis in AIDS with rIL-12 induces an immune response associated with improvement but severe side-effects.15194774Blutt SE, Crawford SE, Warfield KL, Lewis DE, Estes MK, Conner MEJournal of virologyThe VP7 outer capsid protein of rotavirus induces polyclonal B-cell activation. J Virol. 2004 Jul; 78(13):6974-81.J Virol2004-07-01T00:00:002004The VP7 outer capsid protein of rotavirus induces polyclonal B-cell activation.21170046Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia YNature medicineDetrimental effects of adenosine signaling in sickle cell disease. Nat Med. 2011 Jan; 17(1):79-86.Nat Med2010-12-19T00:00:002010Detrimental effects of adenosine signaling in sickle cell disease.15569699Bischoff FZ, Lewis DE, Simpson JLHuman reproduction updateCell-free fetal DNA in maternal blood: kinetics, source and structure. Hum Reprod Update. 2005 Jan-Feb; 11(1):59-67.Hum Reprod Update2004-11-29T00:00:002004Cell-free fetal DNA in maternal blood: kinetics, source and structure.21956514Feske ML, Medina M, Graviss EA, Lewis DEMethods in molecular biology (Clifton, N.J.)IL-7 addition increases spot size and number as measured by T-SPOT.TB (?). Methods Mol Biol. 2012; 792:229-41.Methods Mol Biol2012-01-01T00:00:002012IL-7 addition increases spot size and number as measured by T-SPOT.TB (?).16136475Dann SM, Wang HC, Gambarin KJ, Actor JK, Robinson P, Lewis DE, Caillat-Zucman S, White ACThe Journal of infectious diseasesInterleukin-15 activates human natural killer cells to clear the intestinal protozoan cryptosporidium. J Infect Dis. 2005 Oct 01; 192(7):1294-302.J Infect Dis2005-08-23T00:00:002005Interleukin-15 activates human natural killer cells to clear the intestinal protozoan cryptosporidium.23308014Wu H, Chen L, Zhou Q, Zhang X, Berger S, Bi J, Lewis DE, Xia Y, Zhang WJournal of the American Society of Nephrology : JASNAqp2-expressing cells give rise to renal intercalated cells. J Am Soc Nephrol. 2013 Feb; 24(2):243-52.J Am Soc Nephrol2013-01-10T00:00:002013Aqp2-expressing cells give rise to renal intercalated cells.17827383Preidis GA, Wang HC, Lewis DE, Castellanos-Gonzalez A, Rogers KA, Graviss EA, Ward HD, White ACThe American journal of tropical medicine and hygieneSeropositive human subjects produce interferon gamma after stimulation with recombinant Cryptosporidium hominis gp15. Am J Trop Med Hyg. 2007 Sep; 77(3):583-5.Am J Trop Med Hyg2007-09-01T00:00:002007Seropositive human subjects produce interferon gamma after stimulation with recombinant Cryptosporidium hominis gp15.17079877Jorgez CJ, Dang DD, Simpson JL, Lewis DE, Bischoff FZGenetics in medicine : official journal of the American College of Medical GeneticsQuantity versus quality: optimal methods for cell-free DNA isolation from plasma of pregnant women. Genet Med. 2006 Oct; 8(10):615-9.Genet Med2006-10-01T00:00:002006Quantity versus quality: optimal methods for cell-free DNA isolation from plasma of pregnant women.17967863Pantenburg B, Dann SM, Wang HC, Robinson P, Castellanos-Gonzalez A, Lewis DE, White ACInfection and immunityIntestinal immune response to human Cryptosporidium sp. infection. Infect Immun. 2008 Jan; 76(1):23-9.Infect Immun2007-10-29T00:00:002007Intestinal immune response to human Cryptosporidium sp. infection.18288900Castellanos-Gonzalez A, Yancey LS, Wang HC, Pantenburg B, Liscum KR, Lewis DE, White ACThe Journal of infectious diseasesCryptosporidium infection of human intestinal epithelial cells increases expression of osteoprotegerin: a novel mechanism for evasion of host defenses. J Infect Dis. 2008 Mar 15; 197(6):916-23.J Infect Dis2008-03-15T00:00:002008Cryptosporidium infection of human intestinal epithelial cells increases expression of osteoprotegerin: a novel mechanism for evasion of host defenses.18446791Singh M, Basu S, Camell C, Couturier J, Nudelman RJ, Medina MA, Rodgers JR, Lewis DEEuropean journal of immunologySelective expansion of memory CD4(+) T cells by mitogenic human CD28 generates inflammatory cytokines and regulatory T cells. Eur J Immunol. 2008 Jun; 38(6):1522-32.Eur J Immunol2008-06-01T00:00:002008Selective expansion of memory CD4(+) T cells by mitogenic human CD28 generates inflammatory cytokines and regulatory T cells.18753334Feske M, Nudelman RJ, Medina M, Lew J, Singh M, Couturier J, Graviss EA, Lewis DEClinical and vaccine immunology : CVIEnhancement of human antigen-specific memory T-cell responses by interleukin-7 may improve accuracy in diagnosing tuberculosis. Clin Vaccine Immunol. 2008 Oct; 15(10):1616-22.Clin Vaccine Immunol2008-08-27T00:00:002008Enhancement of human antigen-specific memory T-cell responses by interleukin-7 may improve accuracy in diagnosing tuberculosis.19513105Montes M, Sanchez C, Verdonck K, Lake JE, Gonzalez E, Lopez G, Terashima A, Nolan T, Lewis DE, Gotuzzo E, White ACPLoS neglected tropical diseasesRegulatory T cell expansion in HTLV-1 and strongyloidiasis co-infection is associated with reduced IL-5 responses to Strongyloides stercoralis antigen. PLoS Negl Trop Dis. 2009 Jun 09; 3(6):e456.PLoS Negl Trop Dis2009-06-09T00:00:002009Regulatory T cell expansion in HTLV-1 and strongyloidiasis co-infection is associated with reduced IL-5 responses to Strongyloides stercoralis antigen.27575945Khan IM, Pokharel Y, Dadu RT, Lewis DE, Hoogeveen RC, Wu H, Ballantyne CMThe Journal of clinical endocrinology and metabolismPostprandial Monocyte Activation in Individuals With Metabolic Syndrome. J Clin Endocrinol Metab. 2016 11; 101(11):4195-4204.J Clin Endocrinol Metab2016-08-30T00:00:002016Postprandial Monocyte Activation in Individuals With Metabolic Syndrome.22416257Medina MA, Couturier J, Feske ML, Mahne AE, Turner M, Yu X, Kozinetz CA, Orozco AF, Hutchison AT, Savidge TC, Rodgers JR, Lewis DEJournal of leukocyte biologyGranzyme B- and Fas ligand-mediated cytotoxic function induced by mitogenic CD28 stimulation of human memory CD4+ T cells. J Leukoc Biol. 2012 May; 91(5):759-71.J Leukoc Biol2012-03-13T00:00:002012Granzyme B- and Fas ligand-mediated cytotoxic function induced by mitogenic CD28 stimulation of human memory CD4+ T cells.21177309Montes M, Sanchez C, Lewis DE, Graviss EA, Seas C, Gotuzzo E, White ACThe Journal of infectious diseasesNormalization of FoxP3(+) regulatory T cells in response to effective antiretroviral therapy. J Infect Dis. 2011 Feb 15; 203(4):496-9.J Infect Dis2010-12-21T00:00:002010Normalization of FoxP3(+) regulatory T cells in response to effective antiretroviral therapy.Authorship 784894423157585Zhu W, Shi G, Tang H, Lewis DE, Song XTCurrent HIV researchAn effective vaccination approach augments anti-HIV systemic and vaginal immunity in mice with decreased HIV-1 susceptible a4?7high CD4+ T cells. Curr HIV Res. 2013 Jan; 11(1):56-66.Curr HIV Res2013-01-01T00:00:002013An effective vaccination approach augments anti-HIV systemic and vaginal immunity in mice with decreased HIV-1 susceptible a4?7high CD4+ T cells.15526056Grumelli S, Corry DB, Song LZ, Song L, Green L, Huh J, Hacken J, Espada R, Bag R, Lewis DE, Kheradmand FPLoS medicineAn immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med. 2004 Oct; 1(1):e8.PLoS Med2004-10-19T00:00:002004An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema.17043107Wang HC, Dann SM, Okhuysen PC, Lewis DE, Chappell CL, Adler DG, White ACInfection and immunityHigh levels of CXCL10 are produced by intestinal epithelial cells in AIDS patients with active cryptosporidiosis but not after reconstitution of immunity. Infect Immun. 2007 Jan; 75(1):481-7.Infect Immun2006-10-16T00:00:002006High levels of CXCL10 are produced by intestinal epithelial cells in AIDS patients with active cryptosporidiosis but not after reconstitution of immunity.17263884Lewis DE, Gross KL, Diez MM, Martinez ML, Lukefahr HN, Kozinetz CA, Arduino RCJournal of translational medicineCD8 apoptosis may be a predictor of T cell number normalization after immune reconstitution in HIV. J Transl Med. 2007 Jan 30; 5:9.J Transl Med2007-01-30T00:00:002007CD8 apoptosis may be a predictor of T cell number normalization after immune reconstitution in HIV.17489121Lewis DEResearch initiative, treatment action : RITAHIV vaccines: the future looks promising. Res Initiat Treat Action. 2007; 12(2):29-32.Res Initiat Treat Action2007-01-01T00:00:002007HIV vaccines: the future looks promising.18974299Orozco AF, Jorgez CJ, Horne C, Marquez-Do DA, Chapman MR, Rodgers JR, Bischoff FZ, Lewis DEThe American journal of pathologyMembrane protected apoptotic trophoblast microparticles contain nucleic acids: relevance to preeclampsia. Am J Pathol. 2008 Dec; 173(6):1595-608.Am J Pathol2008-10-30T00:00:002008Membrane protected apoptotic trophoblast microparticles contain nucleic acids: relevance to preeclampsia.21869759Couturier J, Patel SG, Iyer D, Balasubramanyam A, Lewis DEObesity (Silver Spring, Md.)Human monocytes accelerate proliferation and blunt differentiation of preadipocytes in association with suppression of C/EBP? mRNA. Obesity (Silver Spring). 2012 Feb; 20(2):253-62.Obesity (Silver Spring)2011-08-25T00:00:002011Human monocytes accelerate proliferation and blunt differentiation of preadipocytes in association with suppression of C/EBP? mRNA.22448010Tassiopoulos K, Landay A, Collier AC, Connick E, Deeks SG, Hunt P, Lewis DE, Wilson C, Bosch RThe Journal of infectious diseasesCD28-negative CD4+ and CD8+ T cells in antiretroviral therapy-naive HIV-infected adults enrolled in adult clinical trials group studies. J Infect Dis. 2012 Jun; 205(11):1730-8.J Infect Dis2012-03-23T00:00:002012CD28-negative CD4+ and CD8+ T cells in antiretroviral therapy-naive HIV-infected adults enrolled in adult clinical trials group studies.22899596Lewis DECytometry. Part A : the journal of the International Society for Analytical CytologySweat the small stuff. Cytometry A. 2012 Nov; 81(11):933-4.Cytometry A2012-08-15T00:00:002012Sweat the small stuff.Authorship 8800726Authorship 88261515Authorship 8830558Authorship 8830842Authorship 88386910Authorship 8855331029042644Agarwal N, Iyer D, Gabbi C, Saha P, Patel SG, Mo Q, Chang B, Goswami B, Schubert U, Kopp JB, Lewis DE, Balasubramanyam AScientific reportsHIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRa and PPARa dysregulation: implications for HIV-specific pathogenesis of NAFLD. Sci Rep. 2017 10 17; 7(1):13362.Sci Rep2017-10-17T00:00:002017HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRa and PPARa dysregulation: implications for HIV-specific pathogenesis of NAFLD.29401601Zhao S, Adebiyi MG, Zhang Y, Couturier JP, Fan X, Zhang H, Kellems RE, Lewis DE, Xia YFASEB journal : official publication of the Federation of American Societies for Experimental BiologySphingosine-1-phosphate receptor 1 mediates elevated IL-6 signaling to promote chronic inflammation and multitissue damage in sickle cell disease. FASEB J. 2018 05; 32(5):2855-2865.FASEB J2018-01-17T00:00:002018Sphingosine-1-phosphate receptor 1 mediates elevated IL-6 signaling to promote chronic inflammation and multitissue damage in sickle cell disease.29423731Couturier J, Lewis DECurrent HIV/AIDS reportsHIV Persistence in Adipose Tissue Reservoirs. Curr HIV/AIDS Rep. 2018 02; 15(1):60-71.Curr HIV/AIDS Rep2018-02-01T00:00:002018HIV Persistence in Adipose Tissue Reservoirs.29100221Fadul N, Couturier J, Yu X, Kozinetz C, Arduino R, Lewis DESouthern medical journalTreatment-Na?ve HIV-Infected Patients Have Fewer Gut-Homing ?7 Memory CD4 T Cells than Healthy Controls. South Med J. 2017 11; 110(11):709-713.South Med J2017-11-01T00:00:002017Treatment-Na?ve HIV-Infected Patients Have Fewer Gut-Homing ?7 Memory CD4 T Cells than Healthy Controls.29679656Huang Y, Chen Z, Jang JH, Baig MS, Bertolet G, Schroeder C, Huang S, Hu Q, Zhao Y, Lewis DE, Qin L, Zhu MX, Liu DThe Journal of allergy and clinical immunologyPD-1 blocks lytic granule polarization with concomitant impairment of integrin outside-in signaling in the natural killer cell immunological synapse. J Allergy Clin Immunol. 2018 10; 142(4):1311-1321.e8.J Allergy Clin Immunol2018-04-18T00:00:002018PD-1 blocks lytic granule polarization with concomitant impairment of integrin outside-in signaling in the natural killer cell immunological synapse.29630975Couturier J, Winchester LC, Suliburk JW, Wilkerson GK, Podany AT, Agarwal N, Xuan Chua CY, Nehete PN, Nehete BP, Grattoni A, Sastry KJ, Fletcher CV, Lake JE, Balasubramanyam A, Lewis DEAntiviral researchAdipocytes impair efficacy of antiretroviral therapy. Antiviral Res. 2018 06; 154:140-148.Antiviral Res2018-04-06T00:00:002018Adipocytes impair efficacy of antiretroviral therapy.true1Professor EmeritusProfessor Emeritustrue1Associate ProfessorAssociate Professortrue1ProfessorProfessorD000273Anatomy3297730.665428Adipose TissueD053804Chemicals & Drugs73910.960761GranzymesD014779Physiology2527130.746864Virus ReplicationD015496Anatomy44010340.668681CD4-Positive T-LymphocytesAuthorship 9326324D017667Anatomy1693060.835998Adipocytes30036787Liu H, Hu PW, Couturier J, Lewis DE, Rice APVirologyHIV-1 replication in CD4+ T cells exploits the down-regulation of antiviral NEAT1 long non-coding RNAs following T cell activation. Virology. 2018 09; 522:193-198.Virology2018-07-20T00:00:002018HIV-1 replication in CD4+ T cells exploits the down-regulation of antiviral NEAT1 long non-coding RNAs following T cell activation.2000-06-30NIHLEWIS, DOROTHY E1995-07-01ANERGY, APOPTOSIS AND CD28 IN CD8+ T CELLS DURING AIDSR01AI0366821998-05-31NIHLEWIS, DOROTHY E1997-06-01FLOW CYTOMETER FOR MOLECULAR MEDICINE AND HIV RESEARCHS10RR0119092006-07-31NIHLEWIS, DOROTHY E2003-08-15Formation and Function of Human CD28-Negative T CellsR21AI0542512016-08-31NIHLEWIS, DOROTHY E.2014-09-01Adipose Tissue is a significant reservoir for HIVR21AI1162082012-03-31NIHLEWIS, DOROTHY E.1995-07-01ANERGY, APOPTOSIS AND CD28 IN CD8+ T CELLS DURING AIDSR37AI0366822019-08-31NIHLEWIS, DOROTHY E.2014-09-01Adipose Tissue is a significant reservoir for HIVR33AI1162081992-08-31NIHLEWIS, DOROTHY E1985-07-01IMMUNOREGULATION IN ASYMPTOMATIC HIV-INFECTED PEOPLER01AI0225491989-05-15NIHLEWIS, DOROTHY E1988-05-16PURCHASE OF A FLOW CYTOMETERS10RR0039802009-11-30NIHLEWIS, DOROTHY E2004-12-01Molecular Nature of Fetal DNA in Maternal PlasmaR01HD046623Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorDepartment of MedicineDepartment of Molecular Virology & MicrobiologyDepartment of Pathology & ImmunologyImmunologyMedicine-Athero & LipoproteinsMedicine-EndocrinologyMolecular Virology & MicrobiologyPathologyBaylor College of MedicineHUAIZHUWUHUAIZHU WU29.70978600000000-95.39986600000000163WU, HUAIZHUProfessorROGERROSSENROGER ROSSEN0.000000000000000.000000000000002494ROSSEN, ROGERProfessorRICHARD G.COOKRICHARD G. COOK0.000000000000000.000000000000002898COOK, RICHARD G.Professor EmeritusSHANNONHAWKINSSHANNON HAWKINS0.000000000000000.00000000000000478HAWKINS, SHANNONAdjunct Assistant Professor4.19360.0034914356research areas1.012570.015909240coauthor of1165selected publicationsASHOKBALASUBRAMANYAMASHOK BALASUBRAMANYAM0.000000000000000.000000000000003097BALASUBRAMANYAM, ASHOKProfessorNATALIALAPTEVANATALIA LAPTEVA0.000000000000000.00000000000000537LAPTEVA, NATALIAAssociate ProfessorAuthorship 940858930786885Couturier J, Orozco AF, Liu H, Budhiraja S, Siwak EB, Nehete PN, Sastry KJ, Rice AP, Lewis DEVirology journalRegulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells. Virol J. 2019 02 20; 16(1):22.Virol J2019-02-20T00:00:002019Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells.ANDREWRICEANDREW RICE0.000000000000000.000000000000003326RICE, ANDREWProfessorAuthorship 9462161631035848Couturier J, Nuotio-Antar AM, Agarwal N, Wilkerson GK, Saha P, Kulkarni V, Lakhashe SK, Esquivel J, Nehete PN, Ruprecht RM, Sastry KJ, Meyer JM, Hill LR, Lake JE, Balasubramanyam A, Lewis DEAdipocyteLymphocytes upregulate CD36 in adipose tissue and liver. Adipocyte. 2019 12; 8(1):154-163.Adipocyte2019-12-01T00:00:002019Lymphocytes upregulate CD36 in adipose tissue and liver.Authorship 1258858Authorship 1263444Authorship 126439823588945Elhaj M, Charles J, Pedroza C, Liu X, Zhou X, Estrada-Y-Martin RM, Gonzalez EB, Lewis DE, Draeger HT, Kim S, Arnett FC, Mayes MD, Assassi SThe Journal of rheumatologyCan serum surfactant protein D or CC-chemokine ligand 18 predict outcome of interstitial lung disease in patients with early systemic sclerosis? J Rheumatol. 2013 Jul; 40(7):1114-20.J Rheumatol2013-04-15T00:00:002013Can serum surfactant protein D or CC-chemokine ligand 18 predict outcome of interstitial lung disease in patients with early systemic sclerosis?23607267Misra R, Chandra P, Riechman SE, Long DM, Shinde S, Pownall HJ, Coraza I, Lewis DE, Sekhar RV, Balasubramanyam ABMC endocrine disordersRelationship of ethnicity and CD4 Count with glucose metabolism among HIV patients on Highly-Active Antiretroviral Therapy (HAART). BMC Endocr Disord. 2013 Apr 22; 13:13.BMC Endocr Disord2013-04-22T00:00:002013Relationship of ethnicity and CD4 Count with glucose metabolism among HIV patients on Highly-Active Antiretroviral Therapy (HAART).23758320Cimo AM, Ahmed Z, McIntyre BW, Lewis DE, Ladbury JEThe Biochemical journalCD25 and CD69 induction by a4?1 outside-in signalling requires TCR early signalling complex proteins. Biochem J. 2013 Aug 15; 454(1):109-21.Biochem J2013-08-15T00:00:002013CD25 and CD69 induction by a4?1 outside-in signalling requires TCR early signalling complex proteins.Authorship 949035131191549Lewis DE, Lysaght J, Wu HFrontiers in immunologyEditorial: T Cell Alterations in Adipose Tissue During Obesity, HIV, and Cancer. Front Immunol. 2019; 10:1190.Front Immunol2019-05-28T00:00:002019Editorial: T Cell Alterations in Adipose Tissue During Obesity, HIV, and Cancer.true1ProfessorProfessor31759187Liu H, Hu PW, Budhiraja S, Misra A, Couturier J, Lloyd RE, Lewis DE, Kimata JT, Rice APVirologyPACS1 is an HIV-1 cofactor that functions in Rev-mediated nuclear export of viral RNA. Virology. 2020 01 15; 540:88-96.Virology2019-10-19T00:00:002019PACS1 is an HIV-1 cofactor that functions in Rev-mediated nuclear export of viral RNA.NEETIAGARWALNEETI AGARWAL0.000000000000000.000000000000005823AGARWAL, NEETIAssistant ProfessorVANAJAKONDURIVANAJA KONDURI0.000000000000000.000000000000006100KONDURI, VANAJAAssistant Professortrue1ProfessorProfessorAuthorship 1171733Authorship 111821233080776Pons-Faudoa FP, Trani ND, Sizovs A, Shelton KA, Momin Z, Bushman LR, Xu J, Lewis DE, Demaria S, Hawkins T, Rooney JF, Marzinke MA, Kimata JT, Anderson PL, Nehete PN, Arduino RC, Sastry KJ, Grattoni APharmaceuticsViral load Reduction in SHIV-Positive Nonhuman Primates via Long-Acting Subcutaneous Tenofovir Alafenamide Fumarate Release from a Nanofluidic Implant. Pharmaceutics. 2020 Oct 17; 12(10).Pharmaceutics2020-10-17T00:00:002020Viral load Reduction in SHIV-Positive Nonhuman Primates via Long-Acting Subcutaneous Tenofovir Alafenamide Fumarate Release from a Nanofluidic Implant.Authorship 1152546true1Assistant ProfessorAssistant ProfessorAuthorship 1180299Authorship 10376377Authorship 10376528Authorship 1380211124285483Agarwal N, Iyer D, Patel SG, Sekhar RV, Phillips TM, Schubert U, Oplt T, Buras ED, Samson SL, Couturier J, Lewis DE, Rodriguez-Barradas MC, Jahoor F, Kino T, Kopp JB, Balasubramanyam AScience translational medicineHIV-1 Vpr induces adipose dysfunction in vivo through reciprocal effects on PPAR/GR co-regulation. Sci Transl Med. 2013 Nov 27; 5(213):213ra164.Sci Transl Med2013-11-27T00:00:002013HIV-1 Vpr induces adipose dysfunction in vivo through reciprocal effects on PPAR/GR co-regulation.Authorship 1208061Authorship 1055925736708011Skaug B, Guo X, Li YJ, Charles J, Pham KT, Couturier J, Lewis DE, Bracaglia C, Caiello I, Mayes MD, Assassi SRheumatology (Oxford, England)Reduced digestion of circulating genomic DNA in systemic sclerosis patients with the DNASE1L3 R206C variant. Rheumatology (Oxford). 2023 09 01; 62(9):3197-3204.Rheumatology (Oxford)2023-09-01T00:00:002023Reduced digestion of circulating genomic DNA in systemic sclerosis patients with the DNASE1L3 R206C variant.true1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Adjunct ProfessorAdjunct Professortrue1Adjunct Assistant ProfessorAdjunct Assistant Professortrue1Associate ProfessorAssociate ProfessorAuthorship 238678Authorship 222352Authorship 322648Authorship 434651Authorship 456623Authorship 384636Authorship 416961Authorship 474143Authorship 65735524999042Couturier J, Hutchison AT, Medina MA, Gingaras C, Urvil P, Yu X, Nguyen C, Mahale P, Lin L, Kozinetz CA, Schmitz JE, Kimata JT, Savidge TC, Lewis DEVirologyHIV replication in conjunction with granzyme B production by CCR5+ memory CD4 T cells: Implications for bystander cell and tissue pathologies. Virology. 2014 Aug; 462-463:175-88.Virology2014-07-04T00:00:002014HIV replication in conjunction with granzyme B production by CCR5+ memory CD4 T cells: Implications for bystander cell and tissue pathologies.Authorship 14753014Authorship 522017Authorship 729228Authorship 758226Authorship 562733Authorship 563266Authorship 593422Authorship 8378112Authorship 631358Authorship 152984625245659Lin L, Couturier J, Yu X, Medina MA, Kozinetz CA, Lewis DEBMC immunologyGranzyme B secretion by human memory CD4 T cells is less strictly regulated compared to memory CD8 T cells. BMC Immunol. 2014 Sep 24; 15:36.BMC Immunol2014-09-24T00:00:002014Granzyme B secretion by human memory CD4 T cells is less strictly regulated compared to memory CD8 T cells.Authorship 659596Authorship 663211Authorship 684106Authorship 681364Authorship 990624