HUDA ZOGHBI to Neurodegenerative Diseases
This is a "connection" page, showing publications HUDA ZOGHBI has written about Neurodegenerative Diseases.
Connection Strength
2.398
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Pathogenesis of polyglutamine diseases: Piecing together a complex molecular puzzle. J Exp Med. 2026 Jan 05; 223(1).
Score: 0.763
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Mouse and fly models of neurodegeneration. Trends Genet. 2002 Sep; 18(9):463-71.
Score: 0.153
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The role of chaperones in polyglutamine disease. Trends Mol Med. 2002 May; 8(5):232-6.
Score: 0.150
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Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Hum Mol Genet. 2001 Jul 01; 10(14):1511-8.
Score: 0.141
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Glutamine repeats and neurodegeneration. Annu Rev Neurosci. 2000; 23:217-47.
Score: 0.127
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Insights from mouse models into the molecular basis of neurodegeneration. Annu Rev Physiol. 2000; 62:779-802.
Score: 0.127
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Expanding our understanding of polyglutamine diseases through mouse models. Neuron. 1999 Nov; 24(3):499-502.
Score: 0.126
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Polyglutamine diseases: protein cleavage and aggregation. Curr Opin Neurobiol. 1999 Oct; 9(5):566-70.
Score: 0.125
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Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles. JCI Insight. 2018 11 02; 3(21).
Score: 0.118
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Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 Apr; 49(4):527-536.
Score: 0.105
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Neurodegeneration: From cellular concepts to clinical applications. Sci Transl Med. 2016 11 09; 8(364):364ps18.
Score: 0.102
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Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels. Cell. 2015 Mar 12; 160(6):1087-98.
Score: 0.091
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dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1. PLoS Genet. 2007 Dec 28; 3(12):e234.
Score: 0.055
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A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Cell. 2006 May 19; 125(4):801-14.
Score: 0.050
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Diseases of unstable repeat expansion: mechanisms and common principles. Nat Rev Genet. 2005 Oct; 6(10):743-55.
Score: 0.047
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A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration. Neuron. 2002 Jun 13; 34(6):905-19.
Score: 0.038
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Enhanced SUMOylation in polyglutamine diseases. Biochem Biophys Res Commun. 2002 Apr 26; 293(1):307-13.
Score: 0.037
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Identification of genes that modify ataxin-1-induced neurodegeneration. Nature. 2000 Nov 02; 408(6808):101-6.
Score: 0.034
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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice. Cell. 1998 Oct 02; 95(1):41-53.
Score: 0.007