FRANCESCO DEMAYO to Mice, Knockout
This is a "connection" page, showing publications FRANCESCO DEMAYO has written about Mice, Knockout.
Connection Strength
2.385
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Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines. Sci Rep. 2024 09 30; 14(1):22626.
Score: 0.126
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WNK1 regulates uterine homeostasis and its ability to support pregnancy. JCI Insight. 2020 11 19; 5(22).
Score: 0.096
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SFRP4 Is a Negative Regulator of Ovarian Follicle Development and Female Fertility. Endocrinology. 2019 07 01; 160(7):1561-1572.
Score: 0.088
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JNK1/2 represses Lkb1-deficiency-induced lung squamous cell carcinoma progression. Nat Commun. 2019 05 14; 10(1):2148.
Score: 0.087
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FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation. PLoS Genet. 2018 11; 14(11):e1007787.
Score: 0.084
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Comparative analysis of single-stranded DNA donors to generate conditional null mouse alleles. BMC Biol. 2018 Jun 21; 16(1):69.
Score: 0.082
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Mig-6 deficiency cooperates with oncogenic Kras to promote mouse lung tumorigenesis. Lung Cancer. 2017 10; 112:47-56.
Score: 0.077
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The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. PLoS Genet. 2014 Jun; 10(6):e1004451.
Score: 0.062
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Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function. FASEB J. 2012 Mar; 26(3):1218-27.
Score: 0.052
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Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis. Development. 2009 Oct; 136(19):3347-56.
Score: 0.044
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Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A. 2009 May 26; 106(21):8677-82.
Score: 0.043
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In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol. 2008 Apr; 19(2):178-86.
Score: 0.040
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Mouse models of implantation. Trends Endocrinol Metab. 2007 Aug; 18(6):234-9.
Score: 0.038
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Steroid hormone regulation of Clca3 expression in the murine uterus. J Endocrinol. 2006 Jun; 189(3):473-84.
Score: 0.035
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Identification of murine uterine genes regulated in a ligand-dependent manner by the progesterone receptor. Endocrinology. 2005 Aug; 146(8):3490-505.
Score: 0.033
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Progesterone receptor in uterine glands is required for pregnancy establishment in mice. FASEB J. 2025 Mar 31; 39(6):e70495.
Score: 0.033
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Establishment of Murine Pregnancy Requires the Promyelocytic Leukemia Zinc Finger Transcription Factor. Int J Mol Sci. 2024 Mar 19; 25(6).
Score: 0.030
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Genetically engineered mouse models for lung cancer. Annu Rev Physiol. 2004; 66:647-63.
Score: 0.030
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Steroid receptor coactivator-2 drives epithelial reprogramming that enables murine embryo implantation. FASEB J. 2023 12; 37(12):e23313.
Score: 0.030
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Mechanisms of action of estrogen and progesterone. Ann N Y Acad Sci. 2002 Mar; 955:48-59; discussion 86-8, 396-406.
Score: 0.026
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Deficiency of PARP-1 and PARP-2 in the mouse uterus results in decidualization failure and pregnancy loss. Proc Natl Acad Sci U S A. 2021 10 05; 118(40).
Score: 0.026
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Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis. Nat Commun. 2021 06 07; 12(1):3386.
Score: 0.025
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Cell-type specific analysis of physiological action of estrogen in mouse oviducts. FASEB J. 2021 05; 35(5):e21563.
Score: 0.025
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A resource of targeted mutant mouse lines for 5,061 genes. Nat Genet. 2021 04; 53(4):416-419.
Score: 0.025
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Different Cre systems induce differential microRNA landscapes and abnormalities in the female reproductive tracts of Dgcr8 conditional knockout mice. Cell Prolif. 2021 Mar; 54(3):e12996.
Score: 0.024
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Constitutive expression of progesterone receptor isoforms promotes the development of hormone-dependent ovarian neoplasms. Sci Signal. 2020 10 06; 13(652).
Score: 0.024
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Interleukin-13 receptor subunit alpha-2 is a target of progesterone receptor and steroid receptor coactivator-1 in the mouse uterus?. Biol Reprod. 2020 10 05; 103(4):760-768.
Score: 0.024
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Estrogen receptor a (ERa)-binding super-enhancers drive key mediators that control uterine estrogen responses in mice. J Biol Chem. 2020 06 19; 295(25):8387-8400.
Score: 0.023
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KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer. Cancer Cell. 2020 04 13; 37(4):599-617.e7.
Score: 0.023
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Oviductal Retention of Embryos in Female Mice Lacking Estrogen Receptor a in the Isthmus and the Uterus. Endocrinology. 2020 02 01; 161(2).
Score: 0.023
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Insight into the physiological function(s) of uteroglobin by gene-knockout and antisense-transgenic approaches. Ann N Y Acad Sci. 2000; 923:210-33.
Score: 0.023
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The Autophagy Gene Atg16L1 is Necessary for Endometrial Decidualization. Endocrinology. 2020 Jan 01; 161(1).
Score: 0.023
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The histone methyltransferase EZH2 is required for normal uterine development and function in mice?. Biol Reprod. 2019 08 01; 101(2):306-317.
Score: 0.022
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A distal super enhancer mediates estrogen-dependent mouse uterine-specific gene transcription of Igf1 (insulin-like growth factor 1). J Biol Chem. 2019 06 21; 294(25):9746-9759.
Score: 0.022
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Dysregulation of hypothalamic-pituitary estrogen receptor a-mediated signaling causes episodic LH secretion and cystic ovary. FASEB J. 2019 06; 33(6):7375-7386.
Score: 0.021
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Advantages and pitfalls of transgenic and mutant animals. Am J Kidney Dis. 1999 Mar; 33(3):598-600.
Score: 0.021
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Negative elongation factor is essential for endometrial function. FASEB J. 2019 02; 33(2):3010-3023.
Score: 0.021
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Uterine function in the mouse requires speckle-type poz protein. Biol Reprod. 2018 06 01; 98(6):856-869.
Score: 0.020
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IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer. Cancer Immunol Res. 2018 06; 6(6):645-657.
Score: 0.020
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Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization. Mol Hum Reprod. 2017 09 01; 23(9):646-653.
Score: 0.019
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Deletion of RhoA in Progesterone Receptor-Expressing Cells Leads to Luteal Insufficiency and Infertility in Female Mice. Endocrinology. 2017 07 01; 158(7):2168-2178.
Score: 0.019
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Forkhead box a2 (FOXA2) is essential for uterine function and fertility. Proc Natl Acad Sci U S A. 2017 02 07; 114(6):E1018-E1026.
Score: 0.018
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Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development. Oncotarget. 2016 Mar 22; 7(12):14885-97.
Score: 0.017
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Uterine ALK3 is essential during the window of implantation. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):E387-95.
Score: 0.017
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Uterine glucocorticoid receptors are critical for fertility in mice through control of embryo implantation and decidualization. Proc Natl Acad Sci U S A. 2015 Dec 08; 112(49):15166-71.
Score: 0.017
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SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):E6068-77.
Score: 0.017
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Estrogen receptor-a in medial amygdala neurons regulates body weight. J Clin Invest. 2015 Jul 01; 125(7):2861-76.
Score: 0.017
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Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1. Dis Model Mech. 2015 Sep; 8(9):1121-7.
Score: 0.017
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Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesis. Oncogene. 2015 Oct; 34(43):5418-26.
Score: 0.016
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An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action. Nat Med. 2014 Aug; 20(8):919-26.
Score: 0.016
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Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment. Oncogene. 2015 May 07; 34(19):2471-82.
Score: 0.016
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Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution. Elife. 2014 Apr 15; 3:e01694.
Score: 0.015
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Novel DNA motif binding activity observed in vivo with an estrogen receptor a mutant mouse. Mol Endocrinol. 2014 Jun; 28(6):899-911.
Score: 0.015
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A mouse model for endometrioid ovarian cancer arising from the distal oviduct. Int J Cancer. 2014 Sep 01; 135(5):1028-37.
Score: 0.015
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VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy. EMBO Mol Med. 2013 Sep; 5(9):1415-30.
Score: 0.015
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Uterine-specific loss of Tsc2 leads to myometrial tumors in both the uterus and lungs. Mol Endocrinol. 2013 Sep; 27(9):1403-14.
Score: 0.014
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Liver receptor homolog-1 is essential for pregnancy. Nat Med. 2013 Aug; 19(8):1061-6.
Score: 0.014
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BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest. 2013 Jun; 123(6):2539-50.
Score: 0.014
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Alterations in Wnt-?-catenin and Pten signalling play distinct roles in endometrial cancer initiation and progression. J Pathol. 2013 May; 230(1):48-58.
Score: 0.014
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Development and regeneration of Sox2+ endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway. Dev Cell. 2013 Feb 25; 24(4):345-58.
Score: 0.014
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FZD1 regulates cumulus expansion genes and is required for normal female fertility in mice. Biol Reprod. 2012 Nov; 87(5):104.
Score: 0.014
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Nuclear receptor coactivator-6 attenuates uterine estrogen sensitivity to permit embryo implantation. Dev Cell. 2012 Oct 16; 23(4):858-65.
Score: 0.014
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Dysregulation of uterine signaling pathways in progesterone receptor-Cre knockout of dicer. Mol Endocrinol. 2012 Sep; 26(9):1552-66.
Score: 0.014
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Negative regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5. Mol Endocrinol. 2012 Jul; 26(7):1225-34.
Score: 0.013
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Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA. Endocrinology. 2012 Aug; 153(8):3982-94.
Score: 0.013
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CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus. Biol Reprod. 2012 May; 86(5):141, 1-10.
Score: 0.013
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Conditional deletion of Msx homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity. Dev Cell. 2011 Dec 13; 21(6):1014-25.
Score: 0.013
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Connective tissue growth factor is required for normal follicle development and ovulation. Mol Endocrinol. 2011 Oct; 25(10):1740-59.
Score: 0.013
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Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla. Dev Dyn. 2011 Jul; 240(7):1806-14.
Score: 0.012
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The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science. 2011 Feb 18; 331(6019):912-6.
Score: 0.012
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Targeting RANKL to a specific subset of murine mammary epithelial cells induces ordered branching morphogenesis and alveologenesis in the absence of progesterone receptor expression. FASEB J. 2010 Nov; 24(11):4408-19.
Score: 0.012
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Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development. Mol Endocrinol. 2010 Jun; 24(6):1251-66.
Score: 0.012
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The nuclear receptor cofactor receptor-interacting protein 140 is a positive regulator of amphiregulin expression and cumulus cell-oocyte complex expansion in the mouse ovary. Endocrinology. 2010 Jun; 151(6):2923-32.
Score: 0.012
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A mouse model to dissect progesterone signaling in the female reproductive tract and mammary gland. Genesis. 2010 Feb; 48(2):106-13.
Score: 0.011
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Tektin 3 is required for progressive sperm motility in mice. Mol Reprod Dev. 2009 May; 76(5):453-9.
Score: 0.011
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Microarray analysis of somatostatin receptor 5-regulated gene expression profiles in murine pancreas. World J Surg. 2009 Apr; 33(4):630-7.
Score: 0.011
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Deletion of Dicer in somatic cells of the female reproductive tract causes sterility. Mol Endocrinol. 2008 Oct; 22(10):2336-52.
Score: 0.010
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Gap junction communication between uterine stromal cells plays a critical role in pregnancy-associated neovascularization and embryo survival. Development. 2008 Aug; 135(15):2659-68.
Score: 0.010
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Peroxisome proliferator-activated receptor gamma is a target of progesterone regulation in the preovulatory follicles and controls ovulation in mice. Mol Cell Biol. 2008 Mar; 28(5):1770-82.
Score: 0.010
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Generation of a Mig-6 conditional null allele. Genesis. 2007 Nov; 45(11):716-21.
Score: 0.010
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A repressive role for prohibitin in estrogen signaling. Mol Endocrinol. 2008 Feb; 22(2):344-60.
Score: 0.010
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COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet. 2007 Jun; 3(6):e102.
Score: 0.009
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Absence of tektin 4 causes asthenozoospermia and subfertility in male mice. FASEB J. 2007 Apr; 21(4):1013-25.
Score: 0.009
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Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol. 2006 Sep; 26(17):6571-83.
Score: 0.009
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Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. Proc Natl Acad Sci U S A. 2006 May 30; 103(22):8552-7.
Score: 0.009
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Alterations in glucose homeostasis in SSTR1 gene-ablated mice. Mol Cell Endocrinol. 2006 Mar 09; 247(1-2):82-90.
Score: 0.009
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Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol. 2006 Jan; 20(1):45-55.
Score: 0.008
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The effect of global SSTR5 gene ablation on the endocrine pancreas and glucose regulation in aging mice. J Surg Res. 2005 Nov; 129(1):64-72.
Score: 0.008
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Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9487-92.
Score: 0.008
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Cre-mediated recombination in cell lineages that express the progesterone receptor. Genesis. 2005 Feb; 41(2):58-66.
Score: 0.008
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Double-gene ablation of SSTR1 and SSTR5 results in hyperinsulinemia and improved glucose tolerance in mice. Surgery. 2004 Sep; 136(3):585-92.
Score: 0.008
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Progesterone induction of calcitonin expression in the murine mammary gland. J Endocrinol. 2004 Feb; 180(2):287-95.
Score: 0.008
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Induction of cytotoxic T-lymphocyte antigen-2beta, a cysteine protease inhibitor in decidua: a potential regulator of embryo implantation. J Biol Chem. 2004 Mar 12; 279(11):10357-63.
Score: 0.007
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Progesterone involvement in breast development and tumorigenesis--as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids. 2003 Nov; 68(10-13):779-87.
Score: 0.007
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GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility. EMBO J. 2003 Aug 15; 22(16):4070-81.
Score: 0.007
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Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):9744-9.
Score: 0.007
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Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos. Science. 2003 Apr 25; 300(5619):633-6.
Score: 0.007
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Pancreatic somatostatin inhibits insulin secretion via SSTR-5 in the isolated perfused mouse pancreas model. Pancreas. 2003 Apr; 26(3):e67-73.
Score: 0.007
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A genomic approach to identify novel progesterone receptor regulated pathways in the uterus during implantation. Mol Endocrinol. 2002 Dec; 16(12):2853-71.
Score: 0.007
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The embryonic function of germ cell nuclear factor is dependent on the DNA binding domain. J Biol Chem. 2002 Dec 27; 277(52):50660-7.
Score: 0.007
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Deletion of the cancer-amplified coactivator AIB3 results in defective placentation and embryonic lethality. J Biol Chem. 2002 Nov 22; 277(47):45356-60.
Score: 0.007
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Sulfonylurea receptor knockout causes glucose intolerance in mice that is not alleviated by concomitant somatostatin subtype receptor 5 knockout. Ann Surg. 2002 Jun; 235(6):767-74.
Score: 0.007
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Knockout of pentraxin 3, a downstream target of growth differentiation factor-9, causes female subfertility. Mol Endocrinol. 2002 Jun; 16(6):1154-67.
Score: 0.007
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Embryonic expression of an Nkx2-5/Cre gene using ROSA26 reporter mice. Genesis. 2001 Dec; 31(4):176-80.
Score: 0.006
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Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function. Mol Endocrinol. 2001 Jun; 15(6):854-66.
Score: 0.006
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Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation. Mol Cell Biol. 2001 Jan; 21(2):663-77.
Score: 0.006
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Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform. Science. 2000 Sep 08; 289(5485):1751-4.
Score: 0.006
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Regulable expression of inhibin A in wild-type and inhibin alpha null mice. Mol Endocrinol. 2000 Jul; 14(7):1075-85.
Score: 0.006
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Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev. 2000 Jun 15; 14(12):1448-59.
Score: 0.006
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Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion. J Biol Chem. 2000 Mar 31; 275(13):9270-7.
Score: 0.006
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Uteroglobin is essential in preventing immunoglobulin A nephropathy in mice. Nat Med. 1999 Sep; 5(9):1018-25.
Score: 0.006
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Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization. Genes Dev. 1997 Aug 01; 11(15):1925-37.
Score: 0.005
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Reproductive phenotpes of the progesterone receptor null mutant mouse. J Steroid Biochem Mol Biol. 1996 Jan; 56(1-6 Spec No):67-77.
Score: 0.004