ERIC BOERWINKLE to Phenotype
This is a "connection" page, showing publications ERIC BOERWINKLE has written about Phenotype.
Connection Strength
3.240
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Exome sequence association study of levels and longitudinal change of cardiovascular risk factor phenotypes in European Americans and African Americans from the Atherosclerosis Risk in Communities Study. Genet Epidemiol. 2021 09; 45(6):651-663.
Score: 0.085
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Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program. Am J Hum Genet. 2021 05 06; 108(5):874-893.
Score: 0.084
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A biallelic ANTXR1 variant expands the anthrax toxin receptor associated phenotype to tooth agenesis. Am J Med Genet A. 2018 04; 176(4):1015-1022.
Score: 0.068
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Resolution of Disease Phenotypes Resulting from Multilocus Genomic Variation. N Engl J Med. 2017 01 05; 376(1):21-31.
Score: 0.062
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Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data. J Biomed Inform. 2016 Apr; 60:114-9.
Score: 0.059
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Rare variants analysis using penalization methods for whole genome sequence data. BMC Bioinformatics. 2015 Dec 04; 16:405.
Score: 0.058
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Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy. Cell Rep. 2015 Aug 18; 12(7):1169-83.
Score: 0.057
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The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities. Am J Hum Genet. 2015 Aug 06; 97(2):199-215.
Score: 0.056
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Analysis of loss-of-function variants and 20 risk factor phenotypes in 8,554 individuals identifies loci influencing chronic disease. Nat Genet. 2015 Jun; 47(6):640-2.
Score: 0.056
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Global transcriptional disturbances underlie Cornelia de Lange syndrome and related phenotypes. J Clin Invest. 2015 Feb; 125(2):636-51.
Score: 0.054
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Trans-ethnic meta-analysis of white blood cell phenotypes. Hum Mol Genet. 2014 Dec 20; 23(25):6944-60.
Score: 0.053
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Essential hypertension vs. secondary hypertension among children. Am J Hypertens. 2015 Jan; 28(1):73-80.
Score: 0.052
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Genetic determinants influencing human serum metabolome among African Americans. PLoS Genet. 2014 Mar; 10(3):e1004212.
Score: 0.051
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Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate. J Hum Genet. 2013 Jul; 58(7):461-6.
Score: 0.048
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FTO genotype is associated with phenotypic variability of body mass index. Nature. 2012 Oct 11; 490(7419):267-72.
Score: 0.046
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Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study. Atherosclerosis. 2012 Oct; 224(2):435-9.
Score: 0.046
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Multiple loci are associated with white blood cell phenotypes. PLoS Genet. 2011 Jun; 7(6):e1002113.
Score: 0.043
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Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet. 2009 Nov; 41(11):1191-8.
Score: 0.038
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The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods. Ann Hum Genet. 1986 05; 50(2):181-94.
Score: 0.030
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Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participants. Atherosclerosis. 2026 Jan; 412:120603.
Score: 0.029
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Association of metabolomics measurements with blood cell phenotypes. Blood Cells Mol Dis. 2026 Mar; 117:102966.
Score: 0.029
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Genetic study of von Willebrand factor antigen levels = 50 IU/dL identifies variants associated with increased risk of von Willebrand disease and bleeding. J Thromb Haemost. 2025 Aug; 23(8):2410-2421.
Score: 0.028
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Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants. J Am Heart Assoc. 2025 02 18; 14(4):e036499.
Score: 0.027
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A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies. Nat Comput Sci. 2025 02; 5(2):125-143.
Score: 0.027
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Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood. Am J Hum Genet. 2025 02 06; 112(2):276-290.
Score: 0.027
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General Kernel Machine Methods for Multi-Omics Integration and Genome-Wide Association Testing With Related Individuals. Genet Epidemiol. 2025 Jan; 49(1):e22610.
Score: 0.027
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Untargeted metabolome atlas for sleep-related phenotypes in the Hispanic community health study/study of Latinos. EBioMedicine. 2025 Jan; 111:105507.
Score: 0.027
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Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height. Nat Commun. 2024 10 03; 15(1):8549.
Score: 0.027
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NODAL variants are associated with a continuum of laterality defects from simple D-transposition of the great arteries to heterotaxy. Genome Med. 2024 04 03; 16(1):53.
Score: 0.026
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Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development. Nat Commun. 2024 01 15; 15(1):528.
Score: 0.025
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Comparison of strategies for selecting single nucleotide polymorphisms for case/control association studies. Hum Genet. 2003 Aug; 113(3):253-7.
Score: 0.024
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The genetic determinants of recurrent somatic mutations in 43,693 blood genomes. Sci Adv. 2023 04 28; 9(17):eabm4945.
Score: 0.024
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Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies. Nat Genet. 2023 Jan; 55(1):154-164.
Score: 0.024
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Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data. Hum Mol Genet. 2022 11 10; 31(22):3873-3885.
Score: 0.023
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A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies. Nat Methods. 2022 Dec; 19(12):1599-1611.
Score: 0.023
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A saturated map of common genetic variants associated with human height. Nature. 2022 10; 610(7933):704-712.
Score: 0.023
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Rare Variants in Genes Encoding Subunits of the Epithelial Na+ Channel Are Associated With Blood Pressure and Kidney Function. Hypertension. 2022 11; 79(11):2573-2582.
Score: 0.023
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Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative. Hum Mol Genet. 2022 02 03; 31(3):347-361.
Score: 0.022
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Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes. Am J Hum Genet. 2022 01 06; 109(1):81-96.
Score: 0.022
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Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation. Hum Genet. 2022 Jan; 141(1):127-146.
Score: 0.022
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Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program. Am J Hum Genet. 2021 10 07; 108(10):1836-1851.
Score: 0.022
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Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program. Genome Med. 2021 08 26; 13(1):136.
Score: 0.022
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Robust, flexible, and scalable tests for Hardy-Weinberg equilibrium across diverse ancestries. Genetics. 2021 05 17; 218(1).
Score: 0.021
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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 2021 Feb; 590(7845):290-299.
Score: 0.021
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Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nat Commun. 2021 01 05; 12(1):24.
Score: 0.021
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Linkage disequilibrium structure and its impact on the localization of a candidate functional mutation. Genet Epidemiol. 2001; 21 Suppl 1:S620-5.
Score: 0.021
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Alternative genomic diagnoses for individuals with a clinical diagnosis of Dubowitz syndrome. Am J Med Genet A. 2021 01; 185(1):119-133.
Score: 0.020
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Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 2020 10; 586(7831):763-768.
Score: 0.020
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A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos. Am J Hum Genet. 2020 11 05; 107(5):849-863.
Score: 0.020
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Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs. Genome Med. 2020 09 28; 12(1):84.
Score: 0.020
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Efficient gene-environment interaction tests for large biobank-scale sequencing studies. Genet Epidemiol. 2020 11; 44(8):908-923.
Score: 0.020
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Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nat Genet. 2020 Sep; 52(9):969-983.
Score: 0.020
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Biallelic GRM7 variants cause epilepsy, microcephaly, and cerebral atrophy. Ann Clin Transl Neurol. 2020 05; 7(5):610-627.
Score: 0.020
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A Genocentric Approach to Discovery of Mendelian Disorders. Am J Hum Genet. 2019 11 07; 105(5):974-986.
Score: 0.019
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Beta3-adrenergic receptor Trp64Arg polymorphism does not predict incident CHD or carotid intima-media thickness in a community-based sample of whites: the ARIC study. Atherosclerosis Risk in Communities. Hum Genet. 1999 Oct; 105(4):314-9.
Score: 0.019
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Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Am J Epidemiol. 2019 Jun 01; 188(6):1033-1054.
Score: 0.018
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A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet. 2019 06; 51(6):957-972.
Score: 0.018
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Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample. Hum Mol Genet. 2019 04 01; 28(7):1212-1224.
Score: 0.018
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Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels. Circulation. 2019 01 29; 139(5):620-635.
Score: 0.018
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A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology. Blood. 2019 02 28; 133(9):967-977.
Score: 0.018
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Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation. Medicine (Baltimore). 2018 Aug; 97(33):e11865.
Score: 0.017
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Identification of likely pathogenic and known variants in TSPEAR, LAMB3, BCOR, and WNT10A in four Turkish families with tooth agenesis. Hum Genet. 2018 Sep; 137(9):689-703.
Score: 0.017
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Identifying Genes Whose Mutant Transcripts Cause Dominant Disease Traits by Potential Gain-of-Function Alleles. Am J Hum Genet. 2018 08 02; 103(2):171-187.
Score: 0.017
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Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients. J Am Heart Assoc. 2018 03 09; 7(6).
Score: 0.017
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Genome-Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to ?-Blockers. J Am Heart Assoc. 2018 02 24; 7(5).
Score: 0.017
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CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis. J Clin Invest. 2018 03 01; 128(3):1106-1124.
Score: 0.017
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Exome-wide association study of plasma lipids in >300,000 individuals. Nat Genet. 2017 Dec; 49(12):1758-1766.
Score: 0.017
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New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475?000 Individuals. Circ Cardiovasc Genet. 2017 Oct; 10(5).
Score: 0.016
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Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nat Commun. 2017 04 26; 8:14977.
Score: 0.016
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An NPPB Promoter Polymorphism Associated With Elevated N-Terminal pro-B-Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality. J Am Heart Assoc. 2017 Mar 24; 6(4).
Score: 0.016
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Rare and low-frequency coding variants alter human adult height. Nature. 2017 02 09; 542(7640):186-190.
Score: 0.016
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Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities). Arterioscler Thromb Vasc Biol. 2017 03; 37(3):589-597.
Score: 0.016
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Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response. Circ Cardiovasc Genet. 2017 Jan; 10(1).
Score: 0.016
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On Robust Association Testing for Quantitative Traits and Rare Variants. G3 (Bethesda). 2016 12 07; 6(12):3941-3950.
Score: 0.016
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Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis. Circ Cardiovasc Genet. 2016 Dec; 9(6):511-520.
Score: 0.015
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HindIII DNA polymorphism in the lipoprotein lipase gene and plasma lipid phenotypes and carotid artery atherosclerosis. Hum Genet. 1996 Nov; 98(5):551-6.
Score: 0.015
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MIPEP recessive variants cause a syndrome of left ventricular non-compaction, hypotonia, and infantile death. Genome Med. 2016 11 01; 8(1):106.
Score: 0.015
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Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. PLoS Genet. 2016 Oct; 12(10):e1006327.
Score: 0.015
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Recurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes. Am J Hum Genet. 2016 Oct 06; 99(4):831-845.
Score: 0.015
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Exome sequencing in mostly consanguineous Arab families with neurologic disease provides a high potential molecular diagnosis rate. BMC Med Genomics. 2016 07 19; 9(1):42.
Score: 0.015
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Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study. Circ Cardiovasc Genet. 2016 Aug; 9(4):368-74.
Score: 0.015
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An Empirical Comparison of Joint and Stratified Frameworks for Studying G ? E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group. Genet Epidemiol. 2016 07; 40(5):404-15.
Score: 0.015
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PEHO Syndrome May Represent Phenotypic Expansion at the Severe End of the Early-Onset Encephalopathies. Pediatr Neurol. 2016 07; 60:83-7.
Score: 0.015
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The effects of genes implicated in cardiovascular disease on blood pressure response to treatment among treatment-naive hypertensive African Americans in the GenHAT study. J Hum Hypertens. 2016 09; 30(9):549-54.
Score: 0.015
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FLAGS: A Flexible and Adaptive Association Test for Gene Sets Using Summary Statistics. Genetics. 2016 Mar; 202(3):919-29.
Score: 0.015
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GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study. Diabet Med. 2016 07; 33(7):968-75.
Score: 0.014
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Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nat Genet. 2015 Nov; 47(11):1294-1303.
Score: 0.014
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A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nat Genet. 2015 Oct; 47(10):1121-1130.
Score: 0.014
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Rare coding variants and X-linked loci associated with age at menarche. Nat Commun. 2015 Aug 04; 6:7756.
Score: 0.014
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Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference. Obesity (Silver Spring). 2015 Jul; 23(7):1493-501.
Score: 0.014
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Directional dominance on stature and cognition in?diverse human populations. Nature. 2015 Jul 23; 523(7561):459-462.
Score: 0.014
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Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. Atherosclerosis. 2015 Aug; 241(2):419-26.
Score: 0.014
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Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949). Mol Psychiatry. 2015 Feb; 20(2):183-92.
Score: 0.014
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New mutations in the RAB28 gene in 2 Spanish families with cone-rod dystrophy. JAMA Ophthalmol. 2015 Feb; 133(2):133-9.
Score: 0.014
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Genetic overlap between diagnostic subtypes of ischemic stroke. Stroke. 2015 Mar; 46(3):615-9.
Score: 0.014
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Molecular findings among patients referred for clinical whole-exome sequencing. JAMA. 2014 Nov 12; 312(18):1870-9.
Score: 0.013
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Whole exome sequencing identifies novel genes for fetal hemoglobin response to hydroxyurea in children with sickle cell anemia. PLoS One. 2014; 9(10):e110740.
Score: 0.013
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Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet. 2014 Jul 03; 95(1):49-65.
Score: 0.013
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New syndrome with retinitis pigmentosa is caused by nonsense mutations in retinol dehydrogenase RDH11. Hum Mol Genet. 2014 Nov 01; 23(21):5774-80.
Score: 0.013
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Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study. Hum Genet. 2014 Sep; 133(9):1105-16.
Score: 0.013
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An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval. Am J Hum Genet. 2014 Jun 05; 94(6):854-69.
Score: 0.013
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Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. 2014 Aug; 112(4):317-38.
Score: 0.013
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Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program. Atherosclerosis. 2014 Jul; 235(1):84-93.
Score: 0.013
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Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study. Arterioscler Thromb Vasc Biol. 2014 May; 34(5):1069-77.
Score: 0.013
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Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. Am J Hum Genet. 2014 Mar 06; 94(3):349-60.
Score: 0.013
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Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014 Feb 06; 94(2):223-32.
Score: 0.013
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Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. Am J Hum Genet. 2014 Feb 06; 94(2):233-45.
Score: 0.013
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The relation of lipoprotein[a] concentrations and apolipoprotein[a] phenotypes with asymptomatic atherosclerosis in subjects of the Atherosclerosis Risk in Communities (ARIC) Study. Arterioscler Thromb. 1993 Nov; 13(11):1558-66.
Score: 0.013
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Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. Genet Epidemiol. 2013 Dec; 37(8):846-59.
Score: 0.013
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Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol. 2013 Dec; 24(12):2105-17.
Score: 0.012
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Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 2013 May; 45(5):501-12.
Score: 0.012
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Characterizing polymorphisms and allelic diversity of von Willebrand factor gene in the 1000 Genomes. J Thromb Haemost. 2013 Feb; 11(2):261-9.
Score: 0.012
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Impact of genetic polymorphisms of SLC2A2, SLC2A5, and KHK on metabolic phenotypes in hypertensive individuals. PLoS One. 2013; 8(1):e52062.
Score: 0.012
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Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study. Circulation. 2013 Feb 19; 127(7):799-810.
Score: 0.012
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Matrix gla protein gene polymorphism is associated with increased coronary artery calcification progression. Arterioscler Thromb Vasc Biol. 2013 Mar; 33(3):645-51.
Score: 0.012
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Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet. 2012 Nov 02; 91(5):823-38.
Score: 0.012
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Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms. Genetics. 2012 Sep; 192(1):253-66.
Score: 0.011
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A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies. Atherosclerosis. 2012 Aug; 223(2):421-6.
Score: 0.011
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Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature. 2012 Apr 04; 485(7397):242-5.
Score: 0.011
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Chromosome 9p21 single nucleotide polymorphisms are not associated with recurrent myocardial infarction in patients with established coronary artery disease. Circ J. 2012; 76(4):950-6.
Score: 0.011
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Genotype imputation of Metabochip SNPs using a study-specific reference panel of ~4,000 haplotypes in African Americans from the Women's Health Initiative. Genet Epidemiol. 2012 Feb; 36(2):107-17.
Score: 0.011
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Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet. 2012 Feb 01; 5(1):100-12.
Score: 0.011
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Relation of lipid gene scores to longitudinal trends in lipid levels and incidence of abnormal lipid levels among individuals of European ancestry: the Atherosclerosis Risk in Communities (ARIC) study. Circ Cardiovasc Genet. 2012 Feb 01; 5(1):73-80.
Score: 0.011
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A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains. PLoS Genet. 2011 Oct; 7(10):e1002322.
Score: 0.011
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Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet. 2011 Oct; 7(10):e1002298.
Score: 0.011
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Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet. 2011 Sep 11; 43(10):940-7.
Score: 0.011
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Association studies for next-generation sequencing. Genome Res. 2011 Jul; 21(7):1099-108.
Score: 0.011
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A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Diabetes. 2011 Apr; 60(4):1329-39.
Score: 0.010
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Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study. Atherosclerosis. 2011 May; 216(1):151-6.
Score: 0.010
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Association of a fasting glucose genetic risk score with subclinical atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) study. Diabetes. 2011 Jan; 60(1):331-5.
Score: 0.010
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Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010 Oct 14; 467(7317):832-8.
Score: 0.010
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Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010 Aug 05; 466(7307):707-13.
Score: 0.010
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The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions. Genet Epidemiol. 2010 May; 34(4):364-72.
Score: 0.010
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Candidate gene association resource (CARe): design, methods, and proof of concept. Circ Cardiovasc Genet. 2010 Jun; 3(3):267-75.
Score: 0.010
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Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation. 2010 Mar 30; 121(12):1382-92.
Score: 0.010
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Defects in the low density lipoprotein receptor gene affect lipoprotein (a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis. Proc Natl Acad Sci U S A. 1989 Jun; 86(11):4171-4.
Score: 0.009
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Genome-wide association study of blood pressure and hypertension. Nat Genet. 2009 Jun; 41(6):677-87.
Score: 0.009
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Genetics of the quantitative Lp(a) lipoprotein trait. III. Contribution of Lp(a) glycoprotein phenotypes to normal lipid variation. Hum Genet. 1989 Apr; 82(1):73-8.
Score: 0.009
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Genome-wide linkage analysis for uric acid in families enriched for hypertension. Nephrol Dial Transplant. 2009 Aug; 24(8):2414-20.
Score: 0.009
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Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet. 2009 Feb; 2(1):73-80.
Score: 0.009
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Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene. PLoS Genet. 2009 Jan; 5(1):e1000360.
Score: 0.009
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Genetically hypertensive Brown Norway congenic rat strains suggest intermediate traits underlying genetic hypertension. Croat Med J. 2008 Oct; 49(5):586-99.
Score: 0.009
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A whole-genome scan for stroke or myocardial infarction in family blood pressure program families. Stroke. 2008 Apr; 39(4):1115-20.
Score: 0.008
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Regional association-based fine-mapping for sodium-lithium countertransport on chromosome 10. Am J Hypertens. 2008 Jan; 21(1):117-21.
Score: 0.008
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The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability, and covariability of cholesterol, betalipoprotein, and triglycerides in a sample of unrelated individuals. Am J Med Genet. 1987 Jul; 27(3):567-82.
Score: 0.008
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The use of measured genotype information in the analysis of quantitative phenotypes in man. III. Simultaneous estimation of the frequencies and effects of the apolipoprotein E polymorphism and residual polygenetic effects on cholesterol, betalipoprotein and triglyceride levels. Ann Hum Genet. 1987 07; 51(3):211-26.
Score: 0.008
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Replicating genotype-phenotype associations. Nature. 2007 Jun 07; 447(7145):655-60.
Score: 0.008
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Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: a scientific statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group. Circulation. 2007 Jun 05; 115(22):2878-901.
Score: 0.008
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Genetic variations associated with echocardiographic left ventricular traits in hypertensive blacks. Hypertension. 2007 May; 49(5):992-9.
Score: 0.008
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Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat Genet. 2007 Apr; 39(4):513-6.
Score: 0.008
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Genetic architecture of inter-individual variability in apolipoprotein, lipoprotein and lipid phenotypes. Ciba Found Symp. 1987; 130:99-127.
Score: 0.008
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Multiple genes for essential-hypertension susceptibility on chromosome 1q. Am J Hum Genet. 2007 Feb; 80(2):253-64.
Score: 0.008
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Contrasting multi-site genotypic distributions among discordant quantitative phenotypes: the APOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors. Genet Epidemiol. 2006 Sep; 30(6):508-18.
Score: 0.008
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Bias of the contribution of single-locus effects to the variance of a quantitative trait. Am J Hum Genet. 1986 Jul; 39(1):137-44.
Score: 0.008
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Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: the Coronary Artery Risk Development in Young Adults (CARDIA) study. J Thromb Haemost. 2006 06; 4(6):1279-87.
Score: 0.007
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The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability. J Mol Med (Berl). 2006 Jul; 84(7):561-72.
Score: 0.007
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Contribution of regulatory and structural variations in APOE to predicting dyslipidemia. J Lipid Res. 2006 Feb; 47(2):318-28.
Score: 0.007
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Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis. Diabetes. 2005 Mar; 54(3):909-14.
Score: 0.007
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Strategies for elucidating the phenotypic and genetic heterogeneity of a chronic disease with a complex etiology. Prog Clin Biol Res. 1985; 194:39-66.
Score: 0.007
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Pleiotropic genetic effects contribute to the correlation between HDL cholesterol, triglycerides, and LDL particle size in hypertensive sibships. Am J Hypertens. 2005 Jan; 18(1):99-103.
Score: 0.007
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Tree scanning: a method for using haplotype trees in phenotype/genotype association studies. Genetics. 2005 Jan; 169(1):441-53.
Score: 0.007
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Genetics of ultrasonographic carotid atherosclerosis. Arterioscler Thromb Vasc Biol. 2004 Sep; 24(9):1567-77.
Score: 0.007
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Contributions of 18 additional DNA sequence variations in the gene encoding apolipoprotein E to explaining variation in quantitative measures of lipid metabolism. Am J Hum Genet. 2002 Sep; 71(3):501-17.
Score: 0.006
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Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies. Genetics. 2000 Nov; 156(3):1259-75.
Score: 0.005
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Analysis of lipoprotein lipase haplotypes reveals associations not apparent from analysis of the constituent loci. Ann Hum Genet. 1999 Nov; 63(Pt 6):499-510.
Score: 0.005
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The GENNID Study. A resource for mapping the genes that cause NIDDM. Diabetes Care. 1996 Aug; 19(8):864-72.
Score: 0.004
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Apo(a) isoforms predict risk for coronary heart disease. A study in six populations. Arterioscler Thromb. 1992 Oct; 12(10):1214-26.
Score: 0.003
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Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease. J Clin Invest. 1992 Mar; 89(3):1040-6.
Score: 0.003
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The apolipoprotein E polymorphism: a comparison of allele frequencies and effects in nine populations. Am J Hum Genet. 1991 Aug; 49(2):338-49.
Score: 0.003
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Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups. Hum Genet. 1991 Apr; 86(6):607-14.
Score: 0.003
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Frequency and effects of the apolipoprotein A-IV polymorphism. Clin Genet. 1990 Jun; 37(6):435-41.
Score: 0.002
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Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia. N Engl J Med. 1990 May 24; 322(21):1494-9.
Score: 0.002
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Frequency and effect of human apolipoprotein A-IV polymorphism on lipid and lipoprotein levels in an Icelandic population. Hum Genet. 1990 Mar; 84(4):344-6.
Score: 0.002
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Human apolipoprotein A-IV polymorphism: frequency and effect on lipid and lipoprotein levels. Hum Genet. 1988 Aug; 79(4):368-72.
Score: 0.002
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A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. I. Basic theory and an analysis of alcohol dehydrogenase activity in Drosophila. Genetics. 1987 Oct; 117(2):343-51.
Score: 0.002
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Lithium ion transport by erythrocytes of randomly selected blood donors and manic-depressive patients: lack of association with affective illness. Am J Psychiatry. 1986 Apr; 143(4):457-62.
Score: 0.002
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Genetics of primary hypertension. Clin Exp Hypertens A. 1986; 8(4-5):623-51.
Score: 0.002
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Studies of enzyme polymorphism in the Kamuela population of Drosophila mercatorum. III. Effects of variation at the alpha GPD locus and subflight stress on the energy charge and glycolytic intermediate concentrations. Genetics. 1983 Aug; 104(4):661-75.
Score: 0.002