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Connection

ERIC BOERWINKLE to Cardiovascular Diseases

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This is a "connection" page, showing publications ERIC BOERWINKLE has written about Cardiovascular Diseases.
ERIC BOERWINKLE
Connection Strength
4.833
Cardiovascular Diseases
  1. Exome sequence association study of levels and longitudinal change of cardiovascular risk factor phenotypes in European Americans and African Americans from the Atherosclerosis Risk in Communities Study. Genet Epidemiol. 2021 09; 45(6):651-663.
    View in: PubMed
    Score: 0.275
  2. Prospective Study of Epigenetic Age Acceleration and Incidence of Cardiovascular Disease Outcomes in the ARIC Study (Atherosclerosis Risk in Communities). Circ Genom Precis Med. 2018 03; 11(3):e001937.
    View in: PubMed
    Score: 0.218
  3. A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate. OMICS. 2016 08; 20(8):480-4.
    View in: PubMed
    Score: 0.196
  4. Associations Between the Serum Metabolome and All-Cause Mortality Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study. Am J Epidemiol. 2016 Apr 01; 183(7):650-6.
    View in: PubMed
    Score: 0.190
  5. Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data. J Biomed Inform. 2016 Apr; 60:114-9.
    View in: PubMed
    Score: 0.189
  6. TCF7L2 single nucleotide polymorphisms, cardiovascular disease and all-cause mortality: the Atherosclerosis Risk in Communities (ARIC) study. Diabetologia. 2008 Jun; 51(6):968-70.
    View in: PubMed
    Score: 0.110
  7. Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study. Am J Hypertens. 2008 May; 21(5):533-8.
    View in: PubMed
    Score: 0.109
  8. Plasma metabolomic profiles associated with cardiovascular disease in type 2 diabetes from the Trans-Omics for Precision Medicine (TOPMed) program. Atherosclerosis. 2026 Jun; 417:120758.
    View in: PubMed
    Score: 0.096
  9. Identification of allele-specific KIV-2 repeats and impact on Lp(a) measurements for cardiovascular disease risk. BMC Med Genomics. 2024 10 24; 17(1):255.
    View in: PubMed
    Score: 0.087
  10. Dietary Acculturation Is Associated With Altered Gut Microbiome, Circulating Metabolites, and Cardiovascular Disease Risk in US Hispanics and Latinos: Results From HCHS/SOL. Circulation. 2024 Jul 16; 150(3):215-229.
    View in: PubMed
    Score: 0.084
  11. Familial Hypercholesterolemia Variant and Cardiovascular Risk in Individuals With Elevated Cholesterol. JAMA Cardiol. 2024 03 01; 9(3):263-271.
    View in: PubMed
    Score: 0.083
  12. Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk. J Am Heart Assoc. 2023 10 17; 12(20):e029090.
    View in: PubMed
    Score: 0.080
  13. Metabolomic Signatures of Sedentary Behavior and Cardiometabolic Traits in US Hispanics/Latinos: Results from HCHS/SOL. Med Sci Sports Exerc. 2023 10 01; 55(10):1781-1791.
    View in: PubMed
    Score: 0.078
  14. Integrated proteomic and metabolomic modules identified as biomarkers of mortality in the Atherosclerosis Risk in Communities study and the African American Study of Kidney Disease?and Hypertension. Hum Genomics. 2022 11 03; 16(1):53.
    View in: PubMed
    Score: 0.075
  15. Patient and Clinician Perceptions of Precision Cardiology Care: Findings From the HeartCare Study. Circ Genom Precis Med. 2022 12; 15(6):e003605.
    View in: PubMed
    Score: 0.075
  16. Polygenic Risk, Midlife Life's Simple 7, and Lifetime Risk of Stroke. J Am Heart Assoc. 2022 08 02; 11(15):e025703.
    View in: PubMed
    Score: 0.074
  17. Genetic Risk, Midlife Life's Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study. Neurology. 2022 07 11; 99(2):e154-e163.
    View in: PubMed
    Score: 0.074
  18. ADD1 460W allele associated with cardiovascular disease in hypertensive individuals. Hypertension. 2002 Jun; 39(6):1053-7.
    View in: PubMed
    Score: 0.073
  19. Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study. Atherosclerosis. 2022 06; 350:82-89.
    View in: PubMed
    Score: 0.073
  20. Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits. Am J Hum Genet. 2022 04 07; 109(4):669-679.
    View in: PubMed
    Score: 0.072
  21. American Heart Association's Life's Simple 7: Lifestyle Recommendations, Polygenic Risk, and Lifetime Risk of Coronary Heart Disease. Circulation. 2022 03 15; 145(11):808-818.
    View in: PubMed
    Score: 0.072
  22. Genetic testing in ambulatory cardiology clinics reveals high rate of findings with clinical management implications. Genet Med. 2021 12; 23(12):2404-2414.
    View in: PubMed
    Score: 0.069
  23. Dietary factors, gut microbiota, and serum trimethylamine-N-oxide associated with cardiovascular disease in the Hispanic Community Health Study/Study of Latinos. Am J Clin Nutr. 2021 06 01; 113(6):1503-1514.
    View in: PubMed
    Score: 0.068
  24. Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. Eur Heart J. 2021 05 07; 42(18):1742-1756.
    View in: PubMed
    Score: 0.068
  25. Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women. J Clin Endocrinol Metab. 2020 12 01; 105(12).
    View in: PubMed
    Score: 0.066
  26. Genetics of hypertension, target-organ complications, and response to therapy. Circulation. 2000 Nov 14; 102(20 Suppl 4):IV40-5.
    View in: PubMed
    Score: 0.066
  27. Peeking under the peaks: following up genome-wide linkage analyses. Circulation. 2000 Oct 17; 102(16):1877-8.
    View in: PubMed
    Score: 0.066
  28. Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs. Genome Med. 2020 09 28; 12(1):84.
    View in: PubMed
    Score: 0.065
  29. Levels and Change in Galectin-3 and Association With Cardiovascular Events: The ARIC Study. J Am Heart Assoc. 2020 07 07; 9(13):e015405.
    View in: PubMed
    Score: 0.064
  30. Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nat Genet. 2019 10; 51(10):1459-1474.
    View in: PubMed
    Score: 0.061
  31. APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis. J Am Soc Nephrol. 2019 10; 30(10):2027-2036.
    View in: PubMed
    Score: 0.060
  32. HFE H63D Polymorphism and the Risk for Systemic Hypertension, Myocardial Remodeling, and Adverse Cardiovascular Events in the ARIC Study. Hypertension. 2019 01; 73(1):68-74.
    View in: PubMed
    Score: 0.058
  33. Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study. Atherosclerosis. 2019 03; 282:52-56.
    View in: PubMed
    Score: 0.058
  34. Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk. J Am Coll Cardiol. 2018 10 09; 72(15):1763-1773.
    View in: PubMed
    Score: 0.057
  35. Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease. J Am Coll Cardiol. 2018 07 10; 72(2):156-169.
    View in: PubMed
    Score: 0.056
  36. Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population. Hum Genet. 2018 Jan; 137(1):85-94.
    View in: PubMed
    Score: 0.054
  37. Association of Mitochondrial DNA Copy Number With Cardiovascular Disease. JAMA Cardiol. 2017 11 01; 2(11):1247-1255.
    View in: PubMed
    Score: 0.053
  38. Molecular and genetic approaches to the study of cardiovascular disease. J Cardiovasc Risk. 1997 Oct-Dec; 4(5-6):325-31.
    View in: PubMed
    Score: 0.053
  39. Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation. Thromb Haemost. 2017 06 02; 117(6):1083-1092.
    View in: PubMed
    Score: 0.051
  40. Biomarkers and degree of atherosclerosis are independently associated with incident atherosclerotic cardiovascular disease in a primary prevention cohort: The ARIC study. Atherosclerosis. 2016 10; 253:156-163.
    View in: PubMed
    Score: 0.049
  41. Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study. Circ Cardiovasc Genet. 2016 Aug; 9(4):368-74.
    View in: PubMed
    Score: 0.049
  42. The impact of multiple single day blood pressure readings on cardiovascular risk estimation: The Atherosclerosis Risk in Communities study. Eur J Prev Cardiol. 2016 09; 23(14):1529-36.
    View in: PubMed
    Score: 0.047
  43. Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies. Am Heart J. 2016 May; 175:112-20.
    View in: PubMed
    Score: 0.047
  44. Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. PLoS One. 2015; 10(10):e0140496.
    View in: PubMed
    Score: 0.046
  45. Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study. Atherosclerosis. 2015 Aug; 241(2):641-8.
    View in: PubMed
    Score: 0.045
  46. Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study. PLoS One. 2015; 10(6):e0128452.
    View in: PubMed
    Score: 0.045
  47. High-sensitivity troponin T and cardiovascular events in systolic blood pressure categories: atherosclerosis risk in communities study. Hypertension. 2015 Jan; 65(1):78-84.
    View in: PubMed
    Score: 0.043
  48. Association of exome sequences with plasma C-reactive protein levels in >9000 participants. Hum Mol Genet. 2015 Jan 15; 24(2):559-71.
    View in: PubMed
    Score: 0.043
  49. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 2013 Sep 17; 128(12):1310-24.
    View in: PubMed
    Score: 0.040
  50. Cardiovascular biomarkers and subclinical brain disease in the atherosclerosis risk in communities study. Stroke. 2013 Jul; 44(7):1803-8.
    View in: PubMed
    Score: 0.039
  51. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet. 2013 Apr 15; 22(8):1663-78.
    View in: PubMed
    Score: 0.038
  52. RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatment. Pharmacogenomics J. 2013 Aug; 13(4):330-4.
    View in: PubMed
    Score: 0.037
  53. Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study. PLoS One. 2012; 7(3):e34217.
    View in: PubMed
    Score: 0.036
  54. Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation. 2012 Jan 17; 125(2):241-9.
    View in: PubMed
    Score: 0.035
  55. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 Sep 11; 478(7367):103-9.
    View in: PubMed
    Score: 0.035
  56. Pharmacogenetic associations of MMP9 and MMP12 variants with cardiovascular disease in patients with hypertension. PLoS One. 2011; 6(8):e23609.
    View in: PubMed
    Score: 0.035
  57. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation. 2011 Feb 22; 123(7):731-8.
    View in: PubMed
    Score: 0.033
  58. Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circ Cardiovasc Genet. 2010 Dec; 3(6):523-30.
    View in: PubMed
    Score: 0.033
  59. Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study. PLoS One. 2010 Jul 22; 5(7):e11690.
    View in: PubMed
    Score: 0.032
  60. Hypertension in pregnancy as a risk factor for cardiovascular disease later in life. J Hypertens. 2010 Apr; 28(4):826-33.
    View in: PubMed
    Score: 0.032
  61. Association of circulating matrix metalloproteinases with carotid artery characteristics: the Atherosclerosis Risk in Communities Carotid MRI Study. Arterioscler Thromb Vasc Biol. 2010 May; 30(5):1034-42.
    View in: PubMed
    Score: 0.031
  62. Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study. J Am Coll Cardiol. 2009 Dec 15; 54(25):2388-95.
    View in: PubMed
    Score: 0.031
  63. Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ Cardiovasc Genet. 2009 Apr; 2(2):125-33.
    View in: PubMed
    Score: 0.029
  64. Admixture mapping of quantitative trait loci for blood lipids in African-Americans. Hum Mol Genet. 2009 Jun 01; 18(11):2091-8.
    View in: PubMed
    Score: 0.029
  65. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One. 2008; 3(10):e3583.
    View in: PubMed
    Score: 0.029
  66. Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies. BMC Med Genet. 2008 Jun 03; 9:49.
    View in: PubMed
    Score: 0.028
  67. Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension. JAMA. 2008 Jan 23; 299(3):296-307.
    View in: PubMed
    Score: 0.027
  68. Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: a scientific statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group. Circulation. 2007 Jun 05; 115(22):2878-901.
    View in: PubMed
    Score: 0.026
  69. NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study. Pharmacogenet Genomics. 2006 Dec; 16(12):891-9.
    View in: PubMed
    Score: 0.025
  70. Contrasting multi-site genotypic distributions among discordant quantitative phenotypes: the APOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors. Genet Epidemiol. 2006 Sep; 30(6):508-18.
    View in: PubMed
    Score: 0.025
  71. Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: the Coronary Artery Risk Development in Young Adults (CARDIA) study. J Thromb Haemost. 2006 06; 4(6):1279-87.
    View in: PubMed
    Score: 0.024
  72. Pharmacogenetic association of the angiotensin-converting enzyme insertion/deletion polymorphism on blood pressure and cardiovascular risk in relation to antihypertensive treatment: the Genetics of Hypertension-Associated Treatment (GenHAT) study. Circulation. 2005 Jun 28; 111(25):3374-83.
    View in: PubMed
    Score: 0.023
  73. Cardiovascular Risk Factors and Genetic Risk in Transthyretin V142I Carriers. JACC Heart Fail. 2025 01; 13(1):91-101.
    View in: PubMed
    Score: 0.022
  74. Power of a simplified multivariate test for genetic linkage. Ann Hum Genet. 2002 Nov; 66(Pt 5-6):407-17.
    View in: PubMed
    Score: 0.019
  75. Sequence polymorphism at the human apolipoprotein AII gene ( APOA2): unexpected deficit of variation in an African-American sample. Hum Genet. 2002 Jul; 111(1):75-87.
    View in: PubMed
    Score: 0.018
  76. Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nat Commun. 2020 05 21; 11(1):2542.
    View in: PubMed
    Score: 0.016
  77. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet. 2018 10; 50(10):1412-1425.
    View in: PubMed
    Score: 0.014
  78. Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males. Circulation. 1998 May 12; 97(18):1773-9.
    View in: PubMed
    Score: 0.014
  79. Variants for HDL-C, LDL-C, and triglycerides identified from admixture mapping and fine-mapping analysis in African American families. Circ Cardiovasc Genet. 2015 Feb; 8(1):106-13.
    View in: PubMed
    Score: 0.011
  80. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 2014 Oct 02; 514(7520):92-97.
    View in: PubMed
    Score: 0.011
  81. Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study. PLoS One. 2012; 7(4):e35651.
    View in: PubMed
    Score: 0.009
  82. Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans. PLoS One. 2011 Jan 24; 6(1):e14581.
    View in: PubMed
    Score: 0.008
  83. Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients. Pharmacogenet Genomics. 2011 Jan; 21(1):42-9.
    View in: PubMed
    Score: 0.008
  84. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet. 2010 Oct 28; 6(10):e1001184.
    View in: PubMed
    Score: 0.008
  85. Evidence for consistent intragenic and intergenic interactions between SNP effects in the APOA1/C3/A4/A5 gene cluster. Hum Hered. 2006; 61(2):87-96.
    View in: PubMed
    Score: 0.006
  86. Q192R polymorphism of the paraoxanase 1 gene and its association with serum lipoprotein variables and carotid artery intima-media thickness in young adults from a biracial community. The Bogalusa Heart Study. Atherosclerosis. 2004 Nov; 177(1):167-74.
    View in: PubMed
    Score: 0.005
  87. The beta(2)-adrenergic receptor Arg16-gly polymorphism and interactions involving beta(2)- and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study. Metabolism. 2004 Sep; 53(9):1184-91.
    View in: PubMed
    Score: 0.005
  88. Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study. Diabetes. 2003 Jun; 52(6):1568-72.
    View in: PubMed
    Score: 0.005
  89. Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism. Am J Hum Genet. 2000 Oct; 67(4):881-900.
    View in: PubMed
    Score: 0.004
  90. Apolipoprotein E affects serial changes in total and low-density lipoprotein cholesterol in adolescent girls: Project HeartBeat! Metabolism. 1999 Mar; 48(3):285-90.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.