Connection

ERIC BOERWINKLE to Triglycerides

This is a "connection" page, showing publications ERIC BOERWINKLE has written about Triglycerides.
Connection Strength

2.830
  1. APOE modulates the correlation between triglycerides, cholesterol, and CHD through pleiotropy, and gene-by-gene interactions. Genetics. 2013 Dec; 195(4):1397-405.
    View in: PubMed
    Score: 0.326
  2. Carbohydrate intake modifies associations between ANGPTL4[E40K] genotype and HDL-cholesterol concentrations in White men from the Atherosclerosis Risk in Communities (ARIC) study. Atherosclerosis. 2009 Mar; 203(1):214-20.
    View in: PubMed
    Score: 0.227
  3. Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease. J Am Coll Cardiol. 2018 07 10; 72(2):156-169.
    View in: PubMed
    Score: 0.114
  4. Variants for HDL-C, LDL-C, and triglycerides identified from admixture mapping and fine-mapping analysis in African American families. Circ Cardiovasc Genet. 2015 Feb; 8(1):106-13.
    View in: PubMed
    Score: 0.089
  5. Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med. 2014 Jul 03; 371(1):22-31.
    View in: PubMed
    Score: 0.086
  6. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014 Feb 06; 94(2):223-32.
    View in: PubMed
    Score: 0.084
  7. Apolipoprotein E polymorphism influences postprandial retinyl palmitate but not triglyceride concentrations. Am J Hum Genet. 1994 Feb; 54(2):341-60.
    View in: PubMed
    Score: 0.083
  8. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet. 2013 Nov; 45(11):1345-52.
    View in: PubMed
    Score: 0.082
  9. Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. Pharmacogenomics J. 2014 Feb; 14(1):35-40.
    View in: PubMed
    Score: 0.078
  10. Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project. PLoS One. 2012; 7(5):e36473.
    View in: PubMed
    Score: 0.074
  11. Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance. Hepatology. 2011 Feb; 53(2):467-74.
    View in: PubMed
    Score: 0.067
  12. Admixture mapping of quantitative trait loci for blood lipids in African-Americans. Hum Mol Genet. 2009 Jun 01; 18(11):2091-8.
    View in: PubMed
    Score: 0.060
  13. Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. J Clin Invest. 2009 Jan; 119(1):70-9.
    View in: PubMed
    Score: 0.058
  14. Longitudinal changes in triglycerides according to ANGPTL4[E40K] genotype and longitudinal body weight change in the atherosclerosis risk in communities study. Ann Epidemiol. 2008 Nov; 18(11):842-6.
    View in: PubMed
    Score: 0.058
  15. ESR1 polymorphism is associated with plasma lipid and apolipoprotein levels in Caucasians of the Rochester Family Heart Study. J Lipid Res. 2008 Aug; 49(8):1701-6.
    View in: PubMed
    Score: 0.056
  16. The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability, and covariability of cholesterol, betalipoprotein, and triglycerides in a sample of unrelated individuals. Am J Med Genet. 1987 Jul; 27(3):567-82.
    View in: PubMed
    Score: 0.053
  17. Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat Genet. 2007 Apr; 39(4):513-6.
    View in: PubMed
    Score: 0.052
  18. Longitudinal analysis of haplotypes and polymorphisms of the APOA5 and APOC3 genes associated with variation in serum triglyceride levels: the Bogalusa Heart Study. Metabolism. 2006 Dec; 55(12):1574-81.
    View in: PubMed
    Score: 0.051
  19. Genome-wide linkage scans for loci affecting total cholesterol, HDL-C, and triglycerides: the Family Blood Pressure Program. Hum Genet. 2006 Oct; 120(3):371-80.
    View in: PubMed
    Score: 0.050
  20. Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participants. Atherosclerosis. 2026 Jan; 412:120603.
    View in: PubMed
    Score: 0.047
  21. Demographic, environmental, and genetic predictors of metabolic side effects of hydrochlorothiazide treatment in hypertensive subjects. Am J Hypertens. 2005 Aug; 18(8):1077-83.
    View in: PubMed
    Score: 0.046
  22. Pleiotropic genetic effects contribute to the correlation between HDL cholesterol, triglycerides, and LDL particle size in hypertensive sibships. Am J Hypertens. 2005 Jan; 18(1):99-103.
    View in: PubMed
    Score: 0.044
  23. APOA5 polymorphisms influence plasma triglycerides in young, healthy African Americans and whites of the CARDIA Study. J Lipid Res. 2005 Mar; 46(3):564-71.
    View in: PubMed
    Score: 0.044
  24. Q192R polymorphism of the paraoxanase 1 gene and its association with serum lipoprotein variables and carotid artery intima-media thickness in young adults from a biracial community. The Bogalusa Heart Study. Atherosclerosis. 2004 Nov; 177(1):167-74.
    View in: PubMed
    Score: 0.044
  25. Relationship between low-density lipoprotein subclasses and asymptomatic atherosclerosis in subjects from the Atherosclerosis Risk in Communities (ARIC) Study. Biomarkers. 2004 Mar-Apr; 9(2):190-202.
    View in: PubMed
    Score: 0.042
  26. Interaction effect of Serine447Stop variant of the lipoprotein lipase gene and C-514T variant of the hepatic lipase gene on serum triglyceride levels in young adults: the Bogalusa Heart Study. Metabolism. 2003 Oct; 52(10):1337-42.
    View in: PubMed
    Score: 0.041
  27. R219K polymorphism of the ABCA1 gene and its modulation of the variations in serum high-density lipoprotein cholesterol and triglycerides related to age and adiposity in white versus black young adults. The Bogalusa heart study. Metabolism. 2003 Jul; 52(7):930-4.
    View in: PubMed
    Score: 0.040
  28. Influence of lipoprotein lipase serine 447 stop polymorphism on tracking of triglycerides and HDL cholesterol from childhood to adulthood and familial risk of coronary artery disease: the Bogalusa heart study. Atherosclerosis. 2001 Dec; 159(2):367-73.
    View in: PubMed
    Score: 0.036
  29. Metabolic and lifestyle determinants of postprandial lipemia differ from those of fasting triglycerides: The Atherosclerosis Risk In Communities (ARIC) study. Arterioscler Thromb Vasc Biol. 2001 Feb; 21(2):275-81.
    View in: PubMed
    Score: 0.034
  30. Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels. Circ Genom Precis Med. 2020 08; 13(4):e002772.
    View in: PubMed
    Score: 0.032
  31. Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Am J Epidemiol. 2019 Jun 01; 188(6):1033-1054.
    View in: PubMed
    Score: 0.030
  32. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nat Commun. 2019 Jan 22; 10(1):376.
    View in: PubMed
    Score: 0.029
  33. Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos. Lipids Health Dis. 2017 Oct 12; 16(1):200.
    View in: PubMed
    Score: 0.027
  34. Genetic variant showing a positive interaction with beta-blocking agents with a beneficial influence on lipoprotein lipase activity, HDL cholesterol, and triglyceride levels in coronary artery disease patients. The Ser447-stop substitution in the lipoprotein lipase gene. REGRESS Study Group. Circulation. 1997 Jun 17; 95(12):2628-35.
    View in: PubMed
    Score: 0.026
  35. Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities). Arterioscler Thromb Vasc Biol. 2017 03; 37(3):589-597.
    View in: PubMed
    Score: 0.026
  36. HindIII DNA polymorphism in the lipoprotein lipase gene and plasma lipid phenotypes and carotid artery atherosclerosis. Hum Genet. 1996 Nov; 98(5):551-6.
    View in: PubMed
    Score: 0.025
  37. Assessing genetic linkage and association with robust components of variance approaches. Ann Hum Genet. 1996 03; 60(2):143-60.
    View in: PubMed
    Score: 0.024
  38. Variation at the M235T locus of the angiotensinogen gene and essential hypertension: a population-based case-control study from Rochester, Minnesota. Hum Genet. 1995 Sep; 96(3):295-300.
    View in: PubMed
    Score: 0.023
  39. Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. Nature. 2015 Feb 05; 518(7537):102-6.
    View in: PubMed
    Score: 0.022
  40. Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med. 2014 Nov 27; 371(22):2072-82.
    View in: PubMed
    Score: 0.022
  41. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013 Nov; 45(11):1274-1283.
    View in: PubMed
    Score: 0.020
  42. Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet. 2013 Mar; 9(3):e1003379.
    View in: PubMed
    Score: 0.020
  43. Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. Am J Hum Genet. 2013 Jan 10; 92(1):5-14.
    View in: PubMed
    Score: 0.019
  44. Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19751-6.
    View in: PubMed
    Score: 0.019
  45. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet. 2012 Nov 02; 91(5):823-38.
    View in: PubMed
    Score: 0.019
  46. Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations. PLoS Genet. 2012; 8(5):e1002714.
    View in: PubMed
    Score: 0.019
  47. Blood pressure responses and metabolic effects of hydrochlorothiazide and atenolol. Am J Hypertens. 2012 Mar; 25(3):359-65.
    View in: PubMed
    Score: 0.018
  48. Relation of lipid gene scores to longitudinal trends in lipid levels and incidence of abnormal lipid levels among individuals of European ancestry: the Atherosclerosis Risk in Communities (ARIC) study. Circ Cardiovasc Genet. 2012 Feb 01; 5(1):73-80.
    View in: PubMed
    Score: 0.018
  49. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010 Aug 05; 466(7307):707-13.
    View in: PubMed
    Score: 0.016
  50. Candidate gene association resource (CARe): design, methods, and proof of concept. Circ Cardiovasc Genet. 2010 Jun; 3(3):267-75.
    View in: PubMed
    Score: 0.016
  51. Associations of lipoprotein lipase gene polymorphisms with longitudinal plasma lipid trends in young adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study. Circ Cardiovasc Genet. 2010 Apr; 3(2):179-86.
    View in: PubMed
    Score: 0.016
  52. An analysis of genotype effects and their interactions by using the apolipoprotein E polymorphism and longitudinal data. Am J Hum Genet. 1989 Nov; 45(5):793-802.
    View in: PubMed
    Score: 0.016
  53. Genetics of the quantitative Lp(a) lipoprotein trait. III. Contribution of Lp(a) glycoprotein phenotypes to normal lipid variation. Hum Genet. 1989 Apr; 82(1):73-8.
    View in: PubMed
    Score: 0.015
  54. The use of measured genotype information in the analysis of quantitative phenotypes in man. III. Simultaneous estimation of the frequencies and effects of the apolipoprotein E polymorphism and residual polygenetic effects on cholesterol, betalipoprotein and triglyceride levels. Ann Hum Genet. 1987 07; 51(3):211-26.
    View in: PubMed
    Score: 0.013
  55. Contrasting multi-site genotypic distributions among discordant quantitative phenotypes: the APOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors. Genet Epidemiol. 2006 Sep; 30(6):508-18.
    View in: PubMed
    Score: 0.012
  56. A genome scan for loci influencing levels and trends of lipoprotein lipid-related traits since childhood: The Bogalusa Heart Study. Atherosclerosis. 2007 Feb; 190(2):248-55.
    View in: PubMed
    Score: 0.012
  57. Quantitative trait loci influencing low density lipoprotein particle size in African Americans. J Lipid Res. 2006 Jul; 47(7):1457-62.
    View in: PubMed
    Score: 0.012
  58. Contribution of regulatory and structural variations in APOE to predicting dyslipidemia. J Lipid Res. 2006 Feb; 47(2):318-28.
    View in: PubMed
    Score: 0.012
  59. A novel quantitative trait locus on chromosome 1 with pleiotropic effects on HDL-cholesterol and LDL particle size in hypertensive sibships. Am J Hypertens. 2005 Aug; 18(8):1084-90.
    View in: PubMed
    Score: 0.012
  60. The beta(2)-adrenergic receptor Arg16-gly polymorphism and interactions involving beta(2)- and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study. Metabolism. 2004 Sep; 53(9):1184-91.
    View in: PubMed
    Score: 0.011
  61. Ethnic differences in peripheral arterial disease in the NHLBI Genetic Epidemiology Network of Arteriopathy (GENOA) study. Vasc Med. 2003 Nov; 8(4):237-42.
    View in: PubMed
    Score: 0.010
  62. Diagnostic tools in linkage analysis for quantitative traits. Genet Epidemiol. 2003 May; 24(4):302-8.
    View in: PubMed
    Score: 0.010
  63. SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study. Diabetes. 2002 Jan; 51(1):231-7.
    View in: PubMed
    Score: 0.009
  64. Genome-wide linkage analysis reveals evidence of multiple regions that influence variation in plasma lipid and apolipoprotein levels associated with risk of coronary heart disease. Arterioscler Thromb Vasc Biol. 2001 Jun; 21(6):971-8.
    View in: PubMed
    Score: 0.009
  65. Apolipoprotein E affects serial changes in total and low-density lipoprotein cholesterol in adolescent girls: Project HeartBeat! Metabolism. 1999 Mar; 48(3):285-90.
    View in: PubMed
    Score: 0.007
  66. No association between plasma lipoprotein(a) concentrations and the presence or absence of coronary atherosclerosis in African-Americans. Arterioscler Thromb Vasc Biol. 1995 Jul; 15(7):850-5.
    View in: PubMed
    Score: 0.006
  67. Frequency and effects of the apolipoprotein A-IV polymorphism. Clin Genet. 1990 Jun; 37(6):435-41.
    View in: PubMed
    Score: 0.004
  68. Frequency and effect of human apolipoprotein A-IV polymorphism on lipid and lipoprotein levels in an Icelandic population. Hum Genet. 1990 Mar; 84(4):344-6.
    View in: PubMed
    Score: 0.004
  69. Human apolipoprotein A-IV polymorphism: frequency and effect on lipid and lipoprotein levels. Hum Genet. 1988 Aug; 79(4):368-72.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.