SUKYEONGLEESUKYEONG LEE0.000000000000000.00000000000000262LEE, SUKYEONGAssociate Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 1588413Authorship 1588425Authorship 1588431Authorship 15884451952938Lee SY, Kim S, Sweet RM, Suh SWArchives of biochemistry and biophysicsCrystallization and a preliminary X-ray crystallographic study of alpha-amylase from Bacillus licheniformis. Arch Biochem Biophys. 1991 Dec; 291(2):255-7.Arch Biochem Biophys1991-12-01T00:00:001991Crystallization and a preliminary X-ray crystallographic study of alpha-amylase from Bacillus licheniformis.9163741Hwang KY, Song HK, Chang C, Lee J, Lee SY, Kim KK, Choe S, Sweet RM, Suh SWMolecules and cellsCrystal structure of thermostable alpha-amylase from Bacillus licheniformis refined at 1.7 A resolution. Mol Cells. 1997 Apr 30; 7(2):251-8.Mol Cells1997-04-30T00:00:001997Crystal structure of thermostable alpha-amylase from Bacillus licheniformis refined at 1.7 A resolution.Epigenetics & Molecular CarcinogenesisMolecular & Cellular OncologyMD AndersonBLAINEBARTHOLOMEWBLAINE BARTHOLOMEW9892BARTHOLOMEW, BLAINEProfessorOne Baylor PlazaHouston, 77030TX14567920Lee S, Sowa ME, Watanabe YH, Sigler PB, Chiu W, Yoshida M, Tsai FTCellThe structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state. Cell. 2003 Oct 17; 115(2):229-40.Cell2003-10-17T00:00:002003The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state.74Professor14Associate Professor78Professor EmeritusJOHNTAINERJOHN TAINER11926TAINER, JOHNProfessor17244532Haslberger T, Weibezahn J, Zahn R, Lee S, Tsai FT, Bukau B, Mogk AMolecular cellM domains couple the ClpB threading motor with the DnaK chaperone activity. Mol Cell. 2007 Jan 26; 25(2):247-60.Mol Cell2007-01-26T00:00:002007M domains couple the ClpB threading motor with the DnaK chaperone activity.15550247Weibezahn J, Tessarz P, Schlieker C, Zahn R, Maglica Z, Lee S, Zentgraf H, Weber-Ban EU, Dougan DA, Tsai FT, Mogk A, Bukau BCellThermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB. Cell. 2004 Nov 24; 119(5):653-65.Cell2004-11-24T00:00:002004Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB.16725394Rees I, Lee S, Kim H, Tsai FTBiochimica et biophysica actaThe E3 ubiquitin ligase CHIP binds the androgen receptor in a phosphorylation-dependent manner. Biochim Biophys Acta. 2006 Jun; 1764(6):1073-9.Biochim Biophys Acta2006-04-04T00:00:002006The E3 ubiquitin ligase CHIP binds the androgen receptor in a phosphorylation-dependent manner.22634726Biter AB, Lee J, Sung N, Tsai FT, Lee SJournal of structural biologyFunctional analysis of conserved cis- and trans-elements in the Hsp104 protein disaggregating machine. J Struct Biol. 2012 Aug; 179(2):172-80.J Struct Biol2012-05-24T00:00:002012Functional analysis of conserved cis- and trans-elements in the Hsp104 protein disaggregating machine.17244533Lee S, Choi JM, Tsai FTMolecular cellVisualizing the ATPase cycle in a protein disaggregating machine: structural basis for substrate binding by ClpB. Mol Cell. 2007 Jan 26; 25(2):261-71.Mol Cell2007-01-26T00:00:002007Visualizing the ATPase cycle in a protein disaggregating machine: structural basis for substrate binding by ClpB.20404203Lee S, Sielaff B, Lee J, Tsai FTProceedings of the National Academy of Sciences of the United States of AmericaCryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8135-40.Proc Natl Acad Sci U S A2010-04-19T00:00:002010CryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation.21147776Lee S, Augustin S, Tatsuta T, Gerdes F, Langer T, Tsai FTThe Journal of biological chemistryElectron cryomicroscopy structure of a membrane-anchored mitochondrial AAA protease. J Biol Chem. 2011 Feb 11; 286(6):4404-11.J Biol Chem2010-12-08T00:00:002010Electron cryomicroscopy structure of a membrane-anchored mitochondrial AAA protease.22802670Biter AB, Lee S, Sung N, Tsai FTProceedings of the National Academy of Sciences of the United States of AmericaStructural basis for intersubunit signaling in a protein disaggregating machine. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12515-20.Proc Natl Acad Sci U S A2012-07-16T00:00:002012Structural basis for intersubunit signaling in a protein disaggregating machine.23650362Lee J, Kim JH, Biter AB, Sielaff B, Lee S, Tsai FTProceedings of the National Academy of Sciences of the United States of AmericaHeat shock protein (Hsp) 70 is an activator of the Hsp104 motor. Proc Natl Acad Sci U S A. 2013 May 21; 110(21):8513-8.Proc Natl Acad Sci U S A2013-05-06T00:00:002013Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor.D006360Chemicals & Drugs1803100.86178Heat-Shock ProteinsD012441Living Beings2206200.736866Saccharomyces cerevisiaeD020285Procedures482430.85924Cryoelectron MicroscopyD018832Chemicals & Drugs1722640.880445Molecular ChaperonesD000251Chemicals & Drugs1974350.807048Adenosine TriphosphatasesAuthorship 934161130605683Lee S, Roh SH, Lee J, Sung N, Liu J, Tsai FTFCell reportsCryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation. Cell Rep. 2019 01 02; 26(1):29-36.e3.Cell Rep2019-01-02T00:00:002019Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.Department of Molecular & Human GeneticsMolecular & Human GeneticsBaylor College of MedicineYONGCHENGSONGYONGCHENG SONG0.000000000000000.000000000000001486SONG, YONGCHENGProfessorZHENGZHOUZHENG ZHOU0.000000000000000.000000000000002128ZHOU, ZHENGProfessorHIRAMGILBERTHIRAM GILBERT0.000000000000000.000000000000002344GILBERT, HIRAMProfessor EmeritusFRANCISTSAIFRANCIS TSAI0.000000000000000.00000000000000256TSAI, FRANCISProfessor2.159830.0053736693research areas3.300023.300021coauthor of24.63451.9424359similar to1122selected publicationsGRZEGORZIRAGRZEGORZ IRA29.71073630000000-95.39660450000000927IRA, GRZEGORZProfessorBPRASADB PRASAD0.000000000000000.000000000000003226PRASAD, BProfessorSTEVENLUDTKESTEVEN LUDTKE0.000000000000000.0000000000000049LUDTKE, STEVENProfessortrue1ProfessorProfessorMUNDERZAGAARMUNDER ZAGAAR0.000000000000000.000000000000006880ZAGAAR, MUNDERAssociate Professor15037241Lee S, Sowa ME, Choi JM, Tsai FTJournal of structural biologyThe ClpB/Hsp104 molecular chaperone-a protein disaggregating machine. J Struct Biol. 2004 Apr-May; 146(1-2):99-105.J Struct Biol2004-04-01T00:00:002004The ClpB/Hsp104 molecular chaperone-a protein disaggregating machine.true1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Professor EmeritusProfessor Emeritustrue1ProfessorProfessorDepartment of Biochemistry and Molecular PharmacologyBiochemistry & Mol Pharmacologytrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 1397515Authorship 1397522Authorship 1397535Authorship 1397541Authorship 1397551Authorship 1397561Authorship 1397571Authorship 1397582Authorship 1397591Authorship 1397601Authorship 1397611Authorship 1397621Authorship 1397631Authorship 1397644Authorship 1397653Authorship 1397662Authorship 139767117768355Lee S, Tsai FTActa crystallographica. Section F, Structural biology and crystallization communicationsCrystallization and preliminary X-ray crystallographic analysis of a 40 kDa N-terminal fragment of the yeast prion-remodeling factor Hsp104. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Sep 01; 63(Pt 9):784-6.Acta Crystallogr Sect F Struct Biol Cryst Commun2007-08-31T00:00:002007Crystallization and preliminary X-ray crystallographic analysis of a 40 kDa N-terminal fragment of the yeast prion-remodeling factor Hsp104.15943899Lee S, Tsai FTJournal of biochemistry and molecular biologyMolecular chaperones in protein quality control. J Biochem Mol Biol. 2005 May 31; 38(3):259-65.J Biochem Mol Biol2005-05-31T00:00:002005Molecular chaperones in protein quality control.14646112Lee S, Hisayoshi M, Yoshida M, Tsai FTActa crystallographica. Section D, Biological crystallographyCrystallization and preliminary X-ray crystallographic analysis of the Hsp100 chaperone ClpB from Thermus thermophilus. Acta Crystallogr D Biol Crystallogr. 2003 Dec; 59(Pt 12):2334-6.Acta Crystallogr D Biol Crystallogr2003-11-27T00:00:002003Crystallization and preliminary X-ray crystallographic analysis of the Hsp100 chaperone ClpB from Thermus thermophilus.9779796Lee S, Kuhn RJ, Rossmann MGProteinsProbing the potential glycoprotein binding site of sindbis virus capsid protein with dioxane and model building. Proteins. 1998 Nov 01; 33(2):311-7.Proteins1998-11-01T00:00:001998Probing the potential glycoprotein binding site of sindbis virus capsid protein with dioxane and model building.9375011Kovari LC, Momany CA, Miyagi F, Lee S, Campbell S, Vuong B, Vogt VM, Rossmann MGVirologyCrystals of Rous sarcoma virus capsid protein show a helical arrangement of protein subunits. Virology. 1997 Nov 10; 238(1):79-84.Virology1997-11-10T00:00:001997Crystals of Rous sarcoma virus capsid protein show a helical arrangement of protein subunits.9094737Choi HK, Lu G, Lee S, Wengler G, Rossmann MGProteinsStructure of Semliki Forest virus core protein. Proteins. 1997 Mar; 27(3):345-59.Proteins1997-03-01T00:00:001997Structure of Semliki Forest virus core protein.8831786Choi HK, Lee S, Zhang YP, McKinney BR, Wengler G, Rossmann MG, Kuhn RJJournal of molecular biologyStructural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J Mol Biol. 1996 Sep 20; 262(2):151-67.J Mol Biol1996-09-20T00:00:001996Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis.8736552Lee S, Owen KE, Choi HK, Lee H, Lu G, Wengler G, Brown DT, Rossmann MG, Kuhn RJStructure (London, England : 1993)Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly. Structure. 1996 May 15; 4(5):531-41.Structure1996-05-15T00:00:001996Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly.