JEFFREY ROSEN to Mice
This is a "connection" page, showing publications JEFFREY ROSEN has written about Mice.
Connection Strength
2.292
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CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer. JCI Insight. 2024 Sep 17; 9(20).
Score: 0.071
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Targeting eIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer. J Clin Invest. 2023 12 15; 133(24).
Score: 0.067
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Targeted Inhibition of lncRNA Malat1 Alters the Tumor Immune Microenvironment in Preclinical Syngeneic Mouse Models of Triple-Negative Breast Cancer. Cancer Immunol Res. 2023 11 01; 11(11):1462-1479.
Score: 0.067
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Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer. Cancer Res. 2022 06 15; 82(12):2281-2297.
Score: 0.060
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Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics. Cancer Res Commun. 2021 12; 1(3):178-193.
Score: 0.059
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Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition. Nat Commun. 2021 07 12; 12(1):4262.
Score: 0.057
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TIME Is a Great Healer-Targeting Myeloid Cells in the Tumor Immune Microenvironment to Improve Triple-Negative Breast Cancer Outcomes. Cells. 2020 12 23; 10(1).
Score: 0.055
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miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution. Stem Cells. 2018 12; 36(12):1875-1889.
Score: 0.047
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FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation. Cancer Res. 2018 08 01; 78(15):4229-4240.
Score: 0.046
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Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression. Oncogene. 2017 10 26; 36(43):5958-5968.
Score: 0.043
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Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer. Breast Cancer Res. 2015 Nov 18; 17:141.
Score: 0.038
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Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage. Stem Cell Reports. 2015 Sep 08; 5(3):378-91.
Score: 0.038
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The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes. Endocr Relat Cancer. 2015 Dec; 22(6):T161-76.
Score: 0.037
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Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential. Oncogene. 2015 Dec 03; 34(49):5997-6006.
Score: 0.037
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Intratumoral heterogeneity in a Trp53-null mouse model of human breast cancer. Cancer Discov. 2015 May; 5(5):520-33.
Score: 0.036
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Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium. J Cell Biol. 2015 Feb 02; 208(3):351-66.
Score: 0.036
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Plk2 regulates mitotic spindle orientation and mammary gland development. Development. 2014 Apr; 141(7):1562-71.
Score: 0.034
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Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity? Breast Cancer Res. 2014 Jan 29; 16(1):202.
Score: 0.034
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Fibroblast growth factor receptor signaling is essential for normal mammary gland development and stem cell function. Stem Cells. 2013 Jan; 31(1):178-89.
Score: 0.031
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Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation. PLoS Genet. 2012; 8(7):e1002840.
Score: 0.030
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On murine mammary epithelial stem cells: discovery, function, and current status. Cold Spring Harb Perspect Biol. 2012 Apr 01; 4(4):a013268.
Score: 0.030
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Stem cell antigen-1 (sca-1) regulates mammary tumor development and cell migration. PLoS One. 2011; 6(11):e27841.
Score: 0.029
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P190A RhoGAP is required for mammary gland development. Dev Biol. 2011 Dec 01; 360(1):1-10.
Score: 0.029
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Identification and gene expression profiling of tumor-initiating cells isolated from human osteosarcoma cell lines in an orthotopic mouse model. Cancer Biol Ther. 2011 Aug 15; 12(4):278-87.
Score: 0.029
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Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):2778-83.
Score: 0.028
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Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy. Sci Transl Med. 2010 Oct 27; 2(55):55ra79.
Score: 0.027
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Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer. Cancer Res. 2010 Jun 15; 70(12):4868-79.
Score: 0.026
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The ups and downs of miR-205: identifying the roles of miR-205 in mammary gland development and breast cancer. RNA Biol. 2010 May-Jun; 7(3):300-4.
Score: 0.026
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CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland. Stem Cells. 2010 Mar 31; 28(3):535-44.
Score: 0.026
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Selective targeting of radiation-resistant tumor-initiating cells. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3522-7.
Score: 0.026
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A putative role for microRNA-205 in mammary epithelial cell progenitors. J Cell Sci. 2010 Feb 15; 123(Pt 4):606-18.
Score: 0.026
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Chk1 haploinsufficiency results in anemia and defective erythropoiesis. PLoS One. 2010 Jan 05; 5(1):e8581.
Score: 0.026
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Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression. Breast Cancer Res. 2009; 11(4):R61.
Score: 0.025
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The increasing complexity of the cancer stem cell paradigm. Science. 2009 Jun 26; 324(5935):1670-3.
Score: 0.025
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Lactogenic hormonal induction of long distance interactions between beta-casein gene regulatory elements. J Biol Chem. 2009 Aug 21; 284(34):22815-24.
Score: 0.025
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The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis. Proc Natl Acad Sci U S A. 2009 Mar 31; 106(13):5159-64.
Score: 0.024
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Identification of tumor-initiating cells in a p53-null mouse model of breast cancer. Cancer Res. 2008 Jun 15; 68(12):4674-82.
Score: 0.023
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Minireview: hormones and mammary cell fate--what will I become when I grow up? Endocrinology. 2008 Sep; 149(9):4317-21.
Score: 0.023
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Modelling breast cancer: one size does not fit all. Nat Rev Cancer. 2007 Sep; 7(9):659-72.
Score: 0.022
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Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development. Dev Biol. 2007 Sep 01; 309(1):137-49.
Score: 0.021
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Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition. Mol Endocrinol. 2007 Apr; 21(4):987-1000.
Score: 0.021
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Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line. J Cell Sci. 2007 Feb 01; 120(Pt 3):468-77.
Score: 0.021
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WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells. Proc Natl Acad Sci U S A. 2007 Jan 09; 104(2):618-23.
Score: 0.021
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Keratin 6 is not essential for mammary gland development. Breast Cancer Res. 2006; 8(3):R29.
Score: 0.020
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Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers. Mol Endocrinol. 2006 Oct; 20(10):2355-68.
Score: 0.020
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A critical role for the inflammatory response in a mouse model of preneoplastic progression. Cancer Res. 2006 Jun 01; 66(11):5676-85.
Score: 0.020
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P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland. Mol Endocrinol. 2006 Jun; 20(6):1391-405.
Score: 0.019
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Stop! In the name of transforming growth factor-beta: keeping estrogen receptor-alpha-positive mammary epithelial cells from proliferating. Breast Cancer Res. 2006; 8(4):106.
Score: 0.019
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Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model. J Cell Biol. 2005 Nov 21; 171(4):663-73.
Score: 0.019
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Transcriptional profiling of mammary gland side population cells. Stem Cells. 2006 Apr; 24(4):1065-74.
Score: 0.019
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Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice. J Biol Chem. 2005 Oct 28; 280(43):36301-9.
Score: 0.019
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Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway. Cell Rep Med. 2025 Feb 18; 6(2):101941.
Score: 0.018
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Stem/progenitor cells in mouse mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia. 2005 Jan; 10(1):17-24.
Score: 0.018
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Chk1 versus Cdc25: chking one's levels of cellular proliferation. Cell Cycle. 2004 Nov; 3(11):1355-7.
Score: 0.018
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IRE1a silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer. Cell. 2024 Dec 12; 187(25):7248-7266.e34.
Score: 0.018
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Chk1 is haploinsufficient for multiple functions critical to tumor suppression. Cancer Cell. 2004 Jul; 6(1):45-59.
Score: 0.017
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Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins. Genomics. 2003 Oct; 82(4):417-32.
Score: 0.017
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Pregnancy-induced changes in cell-fate in the mammary gland. Breast Cancer Res. 2003; 5(4):192-7.
Score: 0.016
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The role of C/EBPbeta in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia. 2003 Apr; 8(2):191-204.
Score: 0.016
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A beta-catenin survival signal is required for normal lobular development in the mammary gland. J Cell Sci. 2003 Mar 15; 116(Pt 6):1137-49.
Score: 0.016
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p190-B RhoGAP regulates mammary ductal morphogenesis. Mol Endocrinol. 2003 Jun; 17(6):1054-65.
Score: 0.016
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LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells. Cancer Immunol Res. 2023 02 03; 11(2):171-183.
Score: 0.016
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Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development. Mol Endocrinol. 2002 Dec; 16(12):2675-91.
Score: 0.016
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STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential. Oncogene. 2022 11; 41(48):5214-5222.
Score: 0.015
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Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland. J Cell Biol. 2002 May 13; 157(4):703-14.
Score: 0.015
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CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021 07; 125(2):176-189.
Score: 0.014
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Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer. Cell. 2021 01 21; 184(2):384-403.e21.
Score: 0.014
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Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions. Nat Cell Biol. 2020 10; 22(10):1162-1169.
Score: 0.013
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Resistance to natural killer cell immunosurveillance confers a selective advantage to polyclonal metastasis. Nat Cancer. 2020 07; 1(7):709-722.
Score: 0.013
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Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer. J Vis Exp. 2020 05 18; (159).
Score: 0.013
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The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor. Dis Model Mech. 2019 07 05; 12(7).
Score: 0.012
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A transgenic mouse model for mammary carcinogenesis. Oncogene. 1998 Feb 26; 16(8):997-1007.
Score: 0.011
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Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. J Clin Invest. 2018 04 02; 128(4):1283-1299.
Score: 0.011
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Use of PRKO mice to study the role of progesterone in mammary gland development. J Mammary Gland Biol Neoplasia. 1997 Oct; 2(4):343-54.
Score: 0.011
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TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway. Oncogene. 2017 04 27; 36(17):2377-2393.
Score: 0.010
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Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 2016 06; 18(6):632-44.
Score: 0.010
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A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud. PLoS Comput Biol. 2016 Apr; 12(4):e1004839.
Score: 0.010
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The mammary gland as a bioreactor: factors regulating the efficient expression of milk protein-based transgenes. Am J Clin Nutr. 1996 Apr; 63(4):627S-32S.
Score: 0.010
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Engineering transgenes for use in the mammary gland. Genet Eng (N Y). 1996; 18:57-81.
Score: 0.010
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Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer. Breast Cancer Res Treat. 2015 Jul; 152(2):347-56.
Score: 0.009
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The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor. Cell Rep. 2014 Nov 20; 9(4):1318-32.
Score: 0.009
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Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer. Stem Cells Transl Med. 2014 Jul; 3(7):857-66.
Score: 0.009
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The regulation of mammary gland development by hormones, growth factors, and oncogenes. Prog Clin Biol Res. 1994; 387:95-111.
Score: 0.008
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Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biol. 2013 Nov 12; 14(11):R125.
Score: 0.008
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Predicting drug responsiveness in human cancers using genetically engineered mice. Clin Cancer Res. 2013 Sep 01; 19(17):4889-99.
Score: 0.008
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Separation by cell size enriches for mammary stem cell repopulation activity. Stem Cells Transl Med. 2013 Mar; 2(3):199-203.
Score: 0.008
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FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer. Cancer Res. 2013 Mar 15; 73(6):1981-92.
Score: 0.008
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Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties. Sci Rep. 2013; 3:2687.
Score: 0.008
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Targeting CreER(T2) expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis. Transgenic Res. 2012 Oct; 21(5):1117-23.
Score: 0.007
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Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis. PLoS One. 2012; 7(1):e30814.
Score: 0.007
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Casein gene expression: from transfection to transgenics. Cancer Treat Res. 1992; 61:379-97.
Score: 0.007
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Progesterone receptor directly inhibits ?-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications. Mol Endocrinol. 2011 Jun; 25(6):955-68.
Score: 0.007
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Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential. Breast Cancer Res. 2011 Apr 05; 13(2):R41.
Score: 0.007
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The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3665-70.
Score: 0.007
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Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened. Dev Biol. 2011 Apr 01; 352(1):116-27.
Score: 0.007
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Early-onset aging and defective DNA damage response in Cdc14b-deficient mice. Mol Cell Biol. 2011 Apr; 31(7):1470-7.
Score: 0.007
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P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis. Breast Cancer Res. 2010; 12(5):R73.
Score: 0.007
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Genetic manipulation of individual somatic mammary cells in vivo reveals a master role of STAT5a in inducing alveolar fate commitment and lactogenesis even in the absence of ovarian hormones. Dev Biol. 2010 Oct 15; 346(2):196-203.
Score: 0.007
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Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3728-33.
Score: 0.006
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Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival. Cancer Res. 2009 Mar 15; 69(6):2244-51.
Score: 0.006
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An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ. Breast Cancer Res. 2009; 11(5):R66.
Score: 0.006
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Mammary gland macrophages: pleiotropic functions in mammary development. J Mammary Gland Biol Neoplasia. 2006 Oct; 11(3-4):229-38.
Score: 0.005
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Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells. Mol Endocrinol. 2007 Jan; 21(1):106-25.
Score: 0.005
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Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15853-8.
Score: 0.004
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Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice. Cancer Res. 2003 Dec 01; 63(23):8256-63.
Score: 0.004
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Prostate-specific expression of p53(R172L) differentially regulates p21, Bax, and mdm2 to inhibit prostate cancer progression and prolong survival. Mol Cancer Res. 2003 Dec; 1(14):1036-47.
Score: 0.004
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Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation. Cancer Res. 2003 Oct 01; 63(19):6237-43.
Score: 0.004
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Hormone dependence in premalignant mammary progression. Cancer Res. 2003 Mar 01; 63(5):1067-72.
Score: 0.004
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The mineralocorticoid receptor may compensate for the loss of the glucocorticoid receptor at specific stages of mammary gland development. Mol Endocrinol. 2002 Sep; 16(9):2008-18.
Score: 0.004
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Comparative sequence analysis of the mRNAs coding for mouse and rat whey protein. Nucleic Acids Res. 1982 Jun 25; 10(12):3733-44.
Score: 0.004
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Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol. 2002 May 01; 245(1):42-56.
Score: 0.004
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Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium. Mol Endocrinol. 2002 Mar; 16(3):563-70.
Score: 0.004
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Mechanisms of hormonal prevention of breast cancer. Ann N Y Acad Sci. 2001 Dec; 952:23-35.
Score: 0.004
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Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium. J Cell Biol. 2001 Nov 12; 155(4):531-42.
Score: 0.004
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Long term effects of perinatal injection of estrogen and progesterone on the morphological and biochemical development of the mammary gland. Endocrinology. 1980 Mar; 106(3):823-32.
Score: 0.003
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Detection of casein messenger RNA in hormone-dependent mammary cancer by molecular hybridisation. Nature. 1977 Sep 01; 269(5623):83-6.
Score: 0.003
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neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice. Mol Cell Biol. 1997 Jun; 17(6):3155-63.
Score: 0.003
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Quantitation of casein messenger ribonucleic acid sequences using a specific complementary DNA hybridization probe. Biochemistry. 1976 Nov 30; 15(24):5272-80.
Score: 0.003
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Isolation and characterization of purified rat casein messenger ribonucleic acids. Biochemistry. 1976 Nov 30; 15(24):5263-71.
Score: 0.003
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Comparative biochemical studies of adriamycin and daunomycin in leukemic cells. Cancer Res. 1972 Mar; 32(3):511-5.
Score: 0.002
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Inhibitory effect of cortisol in vitro on 2-deoxyglucose uptake and RNA and protein metabolism in lymphosarcoma P1798. Cancer Res. 1972 Feb; 32(2):350-5.
Score: 0.002
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A comparison of the effect of glucocorticoids on glucose uptake and hexokinase activity in lymphosarcoma P1798. Biochim Biophys Acta. 1970 Dec 01; 219(2):447-54.
Score: 0.002
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Inhibition of glucose uptake in lymphosarcoma P1798 by cortisol and its relationship to the biosynthesis of deoxyribonucleic acid. J Biol Chem. 1970 Apr 25; 245(8):2074-80.
Score: 0.002
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Effects of cortisol on DNA metabolism in the sensitive and resistant lines of mouse lymphoma P1798. Cancer Res. 1970 Apr; 30(4):1129-36.
Score: 0.002
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Comparison of the whey acidic protein genes of the rat and mouse. Nucleic Acids Res. 1984 Nov 26; 12(22):8685-97.
Score: 0.001
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Localization of the casein gene family to a single mouse chromosome. J Cell Biol. 1982 Apr; 93(1):199-204.
Score: 0.001
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Difference between mammary epithelial cells from mature virgin and primiparous mice. Cancer Res. 1978 Nov; 38(11 Pt 2):4059-65.
Score: 0.001
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Mammary tumour virus and casein gene transcription during mouse mammary development. Nature. 1978 Oct 05; 275(5679):455-7.
Score: 0.001