JEFFREY ROSEN to Humans
This is a "connection" page, showing publications JEFFREY ROSEN has written about Humans.
Connection Strength
0.796
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CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer. JCI Insight. 2024 Sep 17; 9(20).
Score: 0.026
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Leveraging preclinical models of metastatic breast cancer. Biochim Biophys Acta Rev Cancer. 2024 09; 1879(5):189163.
Score: 0.026
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Targeting eIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer. J Clin Invest. 2023 12 15; 133(24).
Score: 0.025
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Targeted Inhibition of lncRNA Malat1 Alters the Tumor Immune Microenvironment in Preclinical Syngeneic Mouse Models of Triple-Negative Breast Cancer. Cancer Immunol Res. 2023 11 01; 11(11):1462-1479.
Score: 0.025
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Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer. Cancer Res. 2022 06 15; 82(12):2281-2297.
Score: 0.022
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Single-Cell Analysis Unveils the Role of the Tumor Immune Microenvironment and Notch Signaling in Dormant Minimal Residual Disease. Cancer Res. 2022 Mar 01; 82(5):885-899.
Score: 0.022
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Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics. Cancer Res Commun. 2021 12; 1(3):178-193.
Score: 0.022
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Breast cancer heterogeneity through the lens of single-cell analysis and spatial pathologies. Semin Cancer Biol. 2022 07; 82:3-10.
Score: 0.021
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TIME Is a Great Healer-Targeting Myeloid Cells in the Tumor Immune Microenvironment to Improve Triple-Negative Breast Cancer Outcomes. Cells. 2020 12 23; 10(1).
Score: 0.020
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New twists on long noncoding RNAs: from mobile elements to motile cancer cells. RNA Biol. 2020 11; 17(11):1535-1549.
Score: 0.019
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C/EBP? Isoform Specific Gene Regulation: It's a Lot more Complicated than you Think! J Mammary Gland Biol Neoplasia. 2020 03; 25(1):1-12.
Score: 0.019
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Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression. Oncogene. 2017 10 26; 36(43):5958-5968.
Score: 0.016
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The Cellular Origin and Evolution of Breast Cancer. Cold Spring Harb Perspect Med. 2017 Mar 01; 7(3).
Score: 0.016
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Repurposing Antiestrogens for Tumor Immunotherapy. Cancer Discov. 2017 01; 7(1):17-19.
Score: 0.015
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The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes. Endocr Relat Cancer. 2015 Dec; 22(6):T161-76.
Score: 0.014
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Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential. Oncogene. 2015 Dec 03; 34(49):5997-6006.
Score: 0.014
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Intratumoral heterogeneity in a Trp53-null mouse model of human breast cancer. Cancer Discov. 2015 May; 5(5):520-33.
Score: 0.014
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Regulation of mammary epithelial cell homeostasis by lncRNAs. Int J Biochem Cell Biol. 2014 Sep; 54:318-30.
Score: 0.013
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Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity? Breast Cancer Res. 2014 Jan 29; 16(1):202.
Score: 0.013
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Noncoding RNAs involved in mammary gland development and tumorigenesis: there's a long way to go. J Mammary Gland Biol Neoplasia. 2012 Mar; 17(1):43-58.
Score: 0.011
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Mammary gland development & breast cancer; connecting the dots by non-coding RNAs. J Mammary Gland Biol Neoplasia. 2012 Mar; 17(1):1-2.
Score: 0.011
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On hormone action in the mammary gland. Cold Spring Harb Perspect Biol. 2012 Feb 01; 4(2).
Score: 0.011
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Identification and gene expression profiling of tumor-initiating cells isolated from human osteosarcoma cell lines in an orthotopic mouse model. Cancer Biol Ther. 2011 Aug 15; 12(4):278-87.
Score: 0.011
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Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):2778-83.
Score: 0.010
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Wnt and mammary stem cells: hormones cannot fly wingless. Curr Opin Pharmacol. 2010 Dec; 10(6):643-9.
Score: 0.010
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Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy. Sci Transl Med. 2010 Oct 27; 2(55):55ra79.
Score: 0.010
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Small players with big roles: microRNAs as targets to inhibit breast cancer progression. Curr Drug Targets. 2010 Sep; 11(9):1059-73.
Score: 0.010
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Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer. Cancer Res. 2010 Jun 15; 70(12):4868-79.
Score: 0.010
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The ups and downs of miR-205: identifying the roles of miR-205 in mammary gland development and breast cancer. RNA Biol. 2010 May-Jun; 7(3):300-4.
Score: 0.010
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Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. J Mammary Gland Biol Neoplasia. 2010 Jun; 15(2):253-60.
Score: 0.010
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Chk1 haploinsufficiency results in anemia and defective erythropoiesis. PLoS One. 2010 Jan 05; 5(1):e8581.
Score: 0.009
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Chking and executing cell division to prevent genomic instability. Cell Cycle. 2009 Aug; 8(15):2339-42.
Score: 0.009
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The increasing complexity of the cancer stem cell paradigm. Science. 2009 Jun 26; 324(5935):1670-3.
Score: 0.009
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Lactogenic hormonal induction of long distance interactions between beta-casein gene regulatory elements. J Biol Chem. 2009 Aug 21; 284(34):22815-24.
Score: 0.009
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Minireview: hormones and mammary cell fate--what will I become when I grow up? Endocrinology. 2008 Sep; 149(9):4317-21.
Score: 0.008
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The C-terminal domain of the nuclear factor I-B2 isoform is glycosylated and transactivates the WAP gene in the JEG-3 cells. Biochem Biophys Res Commun. 2007 Jul 06; 358(3):770-6.
Score: 0.008
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WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells. Proc Natl Acad Sci U S A. 2007 Jan 09; 104(2):618-23.
Score: 0.008
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Estrogen regulation of mammary gland development and breast cancer: amphiregulin takes center stage. Breast Cancer Res. 2007; 9(4):304.
Score: 0.008
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P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland. Mol Endocrinol. 2006 Jun; 20(6):1391-405.
Score: 0.007
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Stop! In the name of transforming growth factor-beta: keeping estrogen receptor-alpha-positive mammary epithelial cells from proliferating. Breast Cancer Res. 2006; 8(4):106.
Score: 0.007
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Stem cells in the etiology and treatment of cancer. Curr Opin Genet Dev. 2006 Feb; 16(1):60-4.
Score: 0.007
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On mammary stem cells. J Cell Sci. 2005 Aug 15; 118(Pt 16):3585-94.
Score: 0.007
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Stem/progenitor cells in mouse mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia. 2005 Jan; 10(1):17-24.
Score: 0.007
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Chk1 versus Cdc25: chking one's levels of cellular proliferation. Cell Cycle. 2004 Nov; 3(11):1355-7.
Score: 0.007
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IRE1a silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer. Cell. 2024 Dec 12; 187(25):7248-7266.e34.
Score: 0.007
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Will cancer stem cells provide new therapeutic targets? Carcinogenesis. 2005 Apr; 26(4):703-11.
Score: 0.007
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Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins. Genomics. 2003 Oct; 82(4):417-32.
Score: 0.006
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Isolation and characterization of functional mammary gland stem cells. Cell Prolif. 2003 Oct; 36 Suppl 1:17-32.
Score: 0.006
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Striking it rich by data mining. Cell. 2003 Aug 08; 114(3):271-2.
Score: 0.006
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Transcription factors. J Mammary Gland Biol Neoplasia. 2003 Apr; 8(2):143-4.
Score: 0.006
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The role of C/EBPbeta in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia. 2003 Apr; 8(2):191-204.
Score: 0.006
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Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b. J Biol Chem. 2003 May 09; 278(19):17218-27.
Score: 0.006
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LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells. Cancer Immunol Res. 2023 02 03; 11(2):171-183.
Score: 0.006
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The tumor-immune ecosystem in shaping metastasis. Am J Physiol Cell Physiol. 2023 03 01; 324(3):C707-C717.
Score: 0.006
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Mechanisms of cancer metastasis. Semin Cancer Biol. 2022 12; 87:17-31.
Score: 0.006
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STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential. Oncogene. 2022 11; 41(48):5214-5222.
Score: 0.006
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Noncanonical Wnt/Ror2 signaling regulates cell-matrix adhesion to prompt directional tumor cell invasion in breast cancer. Mol Biol Cell. 2022 09 15; 33(11):ar103.
Score: 0.006
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Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers. Sci Transl Med. 2021 Oct 27; 13(617):eabe6201.
Score: 0.005
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CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021 07; 125(2):176-189.
Score: 0.005
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Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer. Cell. 2021 01 21; 184(2):384-403.e21.
Score: 0.005
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Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions. Nat Cell Biol. 2020 10; 22(10):1162-1169.
Score: 0.005
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Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer. J Vis Exp. 2020 05 18; (159).
Score: 0.005
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The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis. Nucleic Acids Res. 2020 03 18; 48(5):2621-2642.
Score: 0.005
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Metastasis Organotropism: Redefining the Congenial Soil. Dev Cell. 2019 05 06; 49(3):375-391.
Score: 0.005
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GSK3? regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer. Breast Cancer Res. 2019 03 07; 21(1):37.
Score: 0.004
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Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. J Clin Invest. 2018 04 02; 128(4):1283-1299.
Score: 0.004
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Composite response elements mediate hormonal and developmental regulation of milk protein gene expression. Biochem Soc Symp. 1998; 63:101-13.
Score: 0.004
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Genome-wide identification and differential analysis of translational initiation. Nat Commun. 2017 11 23; 8(1):1749.
Score: 0.004
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TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway. Oncogene. 2017 04 27; 36(17):2377-2393.
Score: 0.004
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Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 2016 06; 18(6):632-44.
Score: 0.004
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Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers. Dis Model Mech. 2016 07 01; 9(7):749-57.
Score: 0.004
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The mammary gland as a bioreactor: factors regulating the efficient expression of milk protein-based transgenes. Am J Clin Nutr. 1996 Apr; 63(4):627S-32S.
Score: 0.004
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Engineering transgenes for use in the mammary gland. Genet Eng (N Y). 1996; 18:57-81.
Score: 0.004
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Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer. Breast Cancer Res Treat. 2015 Jul; 152(2):347-56.
Score: 0.003
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The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells. Cancer Cell. 2015 Feb 09; 27(2):193-210.
Score: 0.003
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The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor. Cell Rep. 2014 Nov 20; 9(4):1318-32.
Score: 0.003
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STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem Cells. 2014 Oct; 32(10):2571-82.
Score: 0.003
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Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer. Stem Cells Transl Med. 2014 Jul; 3(7):857-66.
Score: 0.003
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The regulation of mammary gland development by hormones, growth factors, and oncogenes. Prog Clin Biol Res. 1994; 387:95-111.
Score: 0.003
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Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biol. 2013 Nov 12; 14(11):R125.
Score: 0.003
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Predicting drug responsiveness in human cancers using genetically engineered mice. Clin Cancer Res. 2013 Sep 01; 19(17):4889-99.
Score: 0.003
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FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer. Cancer Res. 2013 Mar 15; 73(6):1981-92.
Score: 0.003
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Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties. Sci Rep. 2013; 3:2687.
Score: 0.003
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Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis. PLoS One. 2012; 7(1):e30814.
Score: 0.003
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Progesterone receptor directly inhibits ?-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications. Mol Endocrinol. 2011 Jun; 25(6):955-68.
Score: 0.003
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The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression. Cell Cycle. 2011 Feb 15; 10(4):671-9.
Score: 0.003
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The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3665-70.
Score: 0.003
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Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A. 2010 Aug 31; 107(35):15449-54.
Score: 0.002
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The epigenetic landscape of mammary gland development and functional differentiation. J Mammary Gland Biol Neoplasia. 2010 Mar; 15(1):85-100.
Score: 0.002
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Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33):13820-5.
Score: 0.002
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Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival. Cancer Res. 2009 Mar 15; 69(6):2244-51.
Score: 0.002
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An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ. Breast Cancer Res. 2009; 11(5):R66.
Score: 0.002
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Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst. 2008 May 07; 100(9):672-9.
Score: 0.002
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Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells. Mol Endocrinol. 2007 Jan; 21(1):106-25.
Score: 0.002
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Maspin is physically associated with [beta]1 integrin regulating cell adhesion in mammary epithelial cells. FASEB J. 2006 Jul; 20(9):1510-2.
Score: 0.002
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The dynamic mobility of histone H1 is regulated by cyclin/CDK phosphorylation. Mol Cell Biol. 2003 Dec; 23(23):8626-36.
Score: 0.002
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Prostate-specific expression of p53(R172L) differentially regulates p21, Bax, and mdm2 to inhibit prostate cancer progression and prolong survival. Mol Cancer Res. 2003 Dec; 1(14):1036-47.
Score: 0.002
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Rat beta casein cDNA: sequence analysis and evolutionary comparisons. Nucleic Acids Res. 1982 Apr 10; 10(7):2295-307.
Score: 0.001
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Mechanisms of hormonal prevention of breast cancer. Ann N Y Acad Sci. 2001 Dec; 952:23-35.
Score: 0.001