NUMANOEZGUENNUMAN OEZGUEN0.000000000000000.000000000000004686OEZGUEN, NUMANAssistant Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson25404692Joffr? E, von Mentzer A, Abd El Ghany M, Oezguen N, Savidge T, Dougan G, Svennerholm AM, Sj?ling ?Journal of bacteriologyAllele variants of enterotoxigenic Escherichia coli heat-labile toxin are globally transmitted and associated with colonization factors. J Bacteriol. 2015 Jan; 197(2):392-403.J Bacteriol2014-11-17T00:00:002014Allele variants of enterotoxigenic Escherichia coli heat-labile toxin are globally transmitted and associated with colonization factors.Authorship 898813Authorship 895094Authorship 1091453Authorship 161542825404023Li S, Shi L, Yang Z, Zhang Y, Perez-Cordon G, Huang T, Ramsey J, Oezguen N, Savidge TC, Feng HInfection and immunityCritical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis. Infect Immun. 2015 Feb; 83(2):502-13.Infect Immun2014-11-17T00:00:002014Critical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis.Authorship 376651Molecular & Cellular OncologyMD AndersonAuthorship 55113Authorship 628064Authorship 778584Authorship 84411Authorship 943211991354Oezguen N, Adamian L, Xu Y, Rajarathnam K, Braun WJournal of biomolecular NMRAutomated assignment and 3D structure calculations using combinations of 2D homonuclear and 3D heteronuclear NOESY spectra. J Biomol NMR. 2002 Mar; 22(3):249-63.J Biomol NMR2002-03-01T00:00:002002Automated assignment and 3D structure calculations using combinations of 2D homonuclear and 3D heteronuclear NOESY spectra.12124390Murtazina D, Puchkaev AV, Schein CH, Oezguen N, Braun W, Nanavati A, Pikuleva IAThe Journal of biological chemistryMembrane-protein interactions contribute to efficient 27-hydroxylation of cholesterol by mitochondrial cytochrome P450 27A1. J Biol Chem. 2002 Oct 04; 277(40):37582-9.J Biol Chem2002-07-17T00:00:002002Membrane-protein interactions contribute to efficient 27-hydroxylation of cholesterol by mitochondrial cytochrome P450 27A1.15032606Ivanciuc O, Oezguen N, Mathura VS, Schein CH, Xu Y, Braun WCurrent medicinal chemistryUsing property based sequence motifs and 3D modeling to determine structure and functional regions of proteins. Curr Med Chem. 2004 Mar; 11(5):583-93.Curr Med Chem2004-03-01T00:00:002004Using property based sequence motifs and 3D modeling to determine structure and functional regions of proteins.74Professor10Assistant Professor21Chair14Associate Professor46Distinguished Emeritus Professor12445335Schein CH, Ozg?n N, Izumi T, Braun WBMC bioinformaticsTotal sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases. BMC Bioinformatics. 2002 Nov 25; 3:37.BMC Bioinformatics2002-11-25T00:00:002002Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases.JOHNTAINERJOHN TAINER11926TAINER, JOHNProfessorAuthorship 323128227051863Chen D, Oezguen N, Urvil P, Ferguson C, Dann SM, Savidge TCScience advancesRegulation of protein-ligand binding affinity by hydrogen bond pairing. Sci Adv. 2016 03; 2(3):e1501240.Sci Adv2016-03-25T00:00:002016Regulation of protein-ligand binding affinity by hydrogen bond pairing.14730972Izumi T, Schein CH, Oezguen N, Feng Y, Braun WBiochemistryEffects of backbone contacts 3' to the abasic site on the cleavage and the product binding by human apurinic/apyrimidinic endonuclease (APE1). Biochemistry. 2004 Jan 27; 43(3):684-9.Biochemistry2004-01-27T00:00:002004Effects of backbone contacts 3' to the abasic site on the cleavage and the product binding by human apurinic/apyrimidinic endonuclease (APE1).15505785Schein CH, Zhou B, Oezguen N, Mathura VS, Braun WProteinsMolego-based definition of the architecture and specificity of metal-binding sites. Proteins. 2005 Jan 01; 58(1):200-10.Proteins2005-01-01T00:00:002005Molego-based definition of the architecture and specificity of metal-binding sites.18621419Oezguen N, Zhou B, Negi SS, Ivanciuc O, Schein CH, Labesse G, Braun WMolecular immunologyComprehensive 3D-modeling of allergenic proteins and amino acid composition of potential conformational IgE epitopes. Mol Immunol. 2008 Aug; 45(14):3740-7.Mol Immunol2008-07-14T00:00:002008Comprehensive 3D-modeling of allergenic proteins and amino acid composition of potential conformational IgE epitopes.19121639Ivanciuc O, Schein CH, Garcia T, Oezguen N, Negi SS, Braun WRegulatory toxicology and pharmacology : RTPStructural analysis of linear and conformational epitopes of allergens. Regul Toxicol Pharmacol. 2009 Aug; 54(3 Suppl):S11-9.Regul Toxicol Pharmacol2008-12-14T00:00:002008Structural analysis of linear and conformational epitopes of allergens.19299527Kumar S, Qiu H, Oezguen N, Herlyn H, Halpert JR, Wojnowski LDrug metabolism and disposition: the biological fate of chemicalsLigand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. Drug Metab Dispos. 2009 Jun; 37(6):1328-33.Drug Metab Dispos2009-03-19T00:00:002009Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection.20441784Schein CH, Oezguen N, van der Heden van Noort GJ, Filippov DV, Paul A, Kumar E, Braun WPeptidesNMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU). Peptides. 2010 Aug; 31(8):1441-8.Peptides2010-05-02T00:00:002010NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU).1102 BATESHouston, 77030TX22102776Oezguen N, Mantha AK, Izumi T, Schein CH, Mitra S, Braun WBioinformationMD simulation and experimental evidence for Mg?+ binding at the B site in human AP endonuclease 1. Bioinformation. 2011; 7(4):184-98.Bioinformation2011-10-14T00:00:002011MD simulation and experimental evidence for Mg?+ binding at the B site in human AP endonuclease 1.23542007Hegde ML, Tsutakawa SE, Hegde PM, Holthauzen LM, Li J, Oezguen N, Hilser VJ, Tainer JA, Mitra SJournal of molecular biologyThe disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions. J Mol Biol. 2013 Jul 10; 425(13):2359-71.J Mol Biol2013-03-27T00:00:002013The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions.17427952Oezguen N, Schein CH, Peddi SR, Power TD, Izumi T, Braun WProteinsA "moving metal mechanism" for substrate cleavage by the DNA repair endonuclease APE-1. Proteins. 2007 Jul 01; 68(1):313-23.Proteins2007-07-01T00:00:002007A "moving metal mechanism" for substrate cleavage by the DNA repair endonuclease APE-1.17933856Negi SS, Schein CH, Oezguen N, Power TD, Braun WBioinformatics (Oxford, England)InterProSurf: a web server for predicting interacting sites on protein surfaces. Bioinformatics. 2007 Dec 15; 23(24):3397-9.Bioinformatics2007-10-12T00:00:002007InterProSurf: a web server for predicting interacting sites on protein surfaces.18436236Mantha AK, Oezguen N, Bhakat KK, Izumi T, Braun W, Mitra SJournal of molecular biologyUnusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1. J Mol Biol. 2008 May 23; 379(1):28-37.J Mol Biol2008-04-03T00:00:002008Unusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1.18495666Oezguen N, Kumar S, Hindupur A, Braun W, Muralidhara BK, Halpert JRThe Journal of biological chemistryIdentification and analysis of conserved sequence motifs in cytochrome P450 family 2. Functional and structural role of a motif 187RFDYKD192 in CYP2B enzymes. J Biol Chem. 2008 Aug 01; 283(31):21808-16.J Biol Chem2008-05-21T00:00:002008Identification and analysis of conserved sequence motifs in cytochrome P450 family 2. Functional and structural role of a motif 187RFDYKD192 in CYP2B enzymes.18568079Leonard VH, Sinn PL, Hodge G, Miest T, Devaux P, Oezguen N, Braun W, McCray PB, McChesney MB, Cattaneo RThe Journal of clinical investigationMeasles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed. J Clin Invest. 2008 Jul; 118(7):2448-58.J Clin Invest2008-07-01T00:00:002008Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed.Authorship 651967125426333Oezguen N, Kumar SJournal of drug metabolism & toxicologyAnalysis of Cytochrome P450 Conserved Sequence Motifs between Helices E and H: Prediction of Critical Motifs and Residues in Enzyme Functions. J Drug Metab Toxicol. 2011 Aug 30; 2:1000110.J Drug Metab Toxicol2011-08-30T00:00:002011Analysis of Cytochrome P450 Conserved Sequence Motifs between Helices E and H: Prediction of Critical Motifs and Residues in Enzyme Functions.21857653Savidge TC, Urvil P, Oezguen N, Ali K, Choudhury A, Acharya V, Pinchuk I, Torres AG, English RD, Wiktorowicz JE, Loeffelholz M, Kumar R, Shi L, Nie W, Braun W, Herman B, Hausladen A, Feng H, Stamler JS, Pothoulakis CNature medicineHost S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins. Nat Med. 2011 Aug 21; 17(9):1136-41.Nat Med2011-08-21T00:00:002011Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins.21986291Bhavnani SK, Victor S, Calhoun WJ, Busse WW, Bleecker E, Castro M, Ju H, Pillai R, Oezguen N, Bellala G, Brasier ARJournal of biomedical informaticsHow cytokines co-occur across asthma patients: from bipartite network analysis to a molecular-based classification. J Biomed Inform. 2011 Dec; 44 Suppl 1:S24-S30.J Biomed Inform2011-10-01T00:00:002011How cytokines co-occur across asthma patients: from bipartite network analysis to a molecular-based classification.Authorship 840670222356854Oezguen N, Power TD, Urvil P, Feng H, Pothoulakis C, Stamler JS, Braun W, Savidge TCGut microbesClostridial toxins: sensing a target in a hostile gut environment. Gut Microbes. 2012 Jan-Feb; 3(1):35-41.Gut Microbes2012-01-01T00:00:002012Clostridial toxins: sensing a target in a hostile gut environment.28275689Luna RA, Oezguen N, Balderas M, Venkatachalam A, Runge JK, Versalovic J, Veenstra-VanderWeele J, Anderson GM, Savidge T, Williams KCCellular and molecular gastroenterology and hepatologyDistinct Microbiome-Neuroimmune Signatures Correlate With?Functional Abdominal Pain in Children With Autism Spectrum Disorder. Cell Mol Gastroenterol Hepatol. 2017 Mar; 3(2):218-230.Cell Mol Gastroenterol Hepatol2016-12-11T00:00:002016Distinct Microbiome-Neuroimmune Signatures Correlate With?Functional Abdominal Pain in Children With Autism Spectrum Disorder.Authorship 1005491Authorship 872970528457228Labus JS, Hollister EB, Jacobs J, Kirbach K, Oezguen N, Gupta A, Acosta J, Luna RA, Aagaard K, Versalovic J, Savidge T, Hsiao E, Tillisch K, Mayer EAMicrobiomeDifferences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome. Microbiome. 2017 05 01; 5(1):49.Microbiome2017-05-01T00:00:002017Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome.14671112Vongpunsawad S, Oezgun N, Braun W, Cattaneo RJournal of virologySelectively receptor-blind measles viruses: Identification of residues necessary for SLAM- or CD46-induced fusion and their localization on a new hemagglutinin structural model. J Virol. 2004 Jan; 78(1):302-13.J Virol2004-01-01T00:00:002004Selectively receptor-blind measles viruses: Identification of residues necessary for SLAM- or CD46-induced fusion and their localization on a new hemagglutinin structural model.15827201von Messling V, Oezguen N, Zheng Q, Vongpunsawad S, Braun W, Cattaneo RJournal of virologyNearby clusters of hemagglutinin residues sustain SLAM-dependent canine distemper virus entry in peripheral blood mononuclear cells. J Virol. 2005 May; 79(9):5857-62.J Virol2005-05-01T00:00:002005Nearby clusters of hemagglutinin residues sustain SLAM-dependent canine distemper virus entry in peripheral blood mononuclear cells.16498624Schein CH, Volk DE, Oezguen N, Paul AProteinsNovel, structure-based mechanism for uridylylation of the genome-linked peptide (VPg) of picornaviruses. Proteins. 2006 Jun 01; 63(4):719-26.Proteins2006-06-01T00:00:002006Novel, structure-based mechanism for uridylylation of the genome-linked peptide (VPg) of picornaviruses.16540201Schein CH, Oezguen N, Volk DE, Garimella R, Paul A, Braun WPeptidesNMR structure of the viral peptide linked to the genome (VPg) of poliovirus. Peptides. 2006 Jul; 27(7):1676-84.Peptides2006-03-15T00:00:002006NMR structure of the viral peptide linked to the genome (VPg) of poliovirus.18292085Navaratnarajah CK, Vongpunsawad S, Oezguen N, Stehle T, Braun W, Hashiguchi T, Maenaka K, Yanagi Y, Cattaneo RThe Journal of biological chemistryDynamic interaction of the measles virus hemagglutinin with its receptor signaling lymphocytic activation molecule (SLAM, CD150). J Biol Chem. 2008 Apr 25; 283(17):11763-71.J Biol Chem2008-02-21T00:00:002008Dynamic interaction of the measles virus hemagglutinin with its receptor signaling lymphocytic activation molecule (SLAM, CD150).21217701Navaratnarajah CK, Oezguen N, Rupp L, Kay L, Leonard VH, Braun W, Cattaneo RNature structural & molecular biologyThe heads of the measles virus attachment protein move to transmit the fusion-triggering signal. Nat Struct Mol Biol. 2011 Feb; 18(2):128-34.Nat Struct Mol Biol2011-01-09T00:00:002011The heads of the measles virus attachment protein move to transmit the fusion-triggering signal.22859308Apte-Sengupta S, Negi S, Leonard VH, Oezguen N, Navaratnarajah CK, Braun W, Cattaneo RThe Journal of biological chemistryBase of the measles virus fusion trimer head receives the signal that triggers membrane fusion. J Biol Chem. 2012 Sep 21; 287(39):33026-35.J Biol Chem2012-08-02T00:00:002012Base of the measles virus fusion trimer head receives the signal that triggers membrane fusion.Authorship 882738528760934Spinler JK, Auchtung J, Brown A, Boonma P, Oezguen N, Ross CL, Luna RA, Runge J, Versalovic J, Peniche A, Dann SM, Britton RA, Haag A, Savidge TCInfection and immunityNext-Generation Probiotics Targeting Clostridium difficile through Precursor-Directed Antimicrobial Biosynthesis. Infect Immun. 2017 10; 85(10).Infect Immun2017-09-20T00:00:002017Next-Generation Probiotics Targeting Clostridium difficile through Precursor-Directed Antimicrobial Biosynthesis.true1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessorD016175AnatomyConcepts & Ideas35450.964546B-Lymphocyte SubsetsD001528Disorders16170.969402Behcet SyndromeD008958Concepts & Ideas49317280.67932Models, MolecularD009103Disorders1243480.753741Multiple SclerosisDepartment of Molecular Virology & MicrobiologyDepartment of Pathology & ImmunologyMolecular Virology & MicrobiologyPathologyBaylor College of MedicineUniversity of Houston College of PharmacyJENNIFERSPINLERJENNIFER SPINLER29.71073630000000-95.396604500000001036SPINLER, JENNIFERAssistant ProfessorSRIDEVIDEVARAJSRIDEVI DEVARAJ0.000000000000000.000000000000001943DEVARAJ, SRIDEVIProfessorAuthorship 1103043JOSEPHPETROSINOJOSEPH PETROSINO-33.9553329000000018.461081000000002154PETROSINO, JOSEPHProfessor1.220740.00708487284research areas1.428150.029161435coauthor of51.60493.4891860similar to1154selected publicationsDANIELGRIMMERDANIEL GRIMMER0.000000000000000.00000000000000937GRIMMER, DANIELAssistant ProfessorRUTHLUNARUTH LUNA0.000000000000000.000000000000003631LUNA, RUTHAssociate ProfessorADEKUNLEADESINAADEKUNLE ADESINA0.000000000000000.00000000000000446ADESINA, ADEKUNLEDistinguished Emeritus ProfessorKEVINGAREYKEVIN W. GAREY29.70508570000000-95.401808700000004636GAREY, KEVINProfessor. Chair, Department of Pharmacy Practice and Translational Research.LISECOPELISE COPE0.000000000000000.000000000000001795COPE, LISEAssistant ProfessorMARYGRESIKMARY GRESIK0.000000000000000.000000000000002835GRESIK, MARYDistinguished Emeritus ProfessorJAMESVERSALOVICJAMES VERSALOVIC0.000000000000000.000000000000003197VERSALOVIC, JAMESProfessorTORSAVIDGETOR SAVIDGE0.000000000000000.000000000000004547SAVIDGE, TORProfessorAuthorship 945504231005411Hollister EB, Oezguen N, Chumpitazi BP, Luna RA, Weidler EM, Rubio-Gonzales M, Dahdouli M, Cope JL, Mistretta TA, Raza S, Metcalf GA, Muzny DM, Gibbs RA, Petrosino JF, Heitkemper M, Savidge TC, Shulman RJ, Versalovic JThe Journal of molecular diagnostics : JMDLeveraging Human Microbiome Features to Diagnose and Stratify Children with Irritable Bowel Syndrome. J Mol Diagn. 2019 05; 21(3):449-461.J Mol Diagn2019-04-17T00:00:002019Leveraging Human Microbiome Features to Diagnose and Stratify Children with Irritable Bowel Syndrome.D064307Living Beings2235510.61432MicrobiotaAuthorship 948437131172918Oezguen N, Yalcinkaya N, K?c?kali CI, Dahdouli M, Hollister EB, Luna RA, T?rkoglu R, K?rt?nc? M, Eraksoy M, Savidge TC, T?z?n EClinical and experimental rheumatologyMicrobiota stratification identifies disease-specific alterations in neuro-Beh?et's disease and multiple sclerosis. Clin Exp Rheumatol. 2019 Nov-Dec; 37 Suppl 121(6):58-66.Clin Exp Rheumatol2019-05-30T00:00:002019Microbiota stratification identifies disease-specific alterations in neuro-Beh?et's disease and multiple sclerosis.80Professor. Chair, Department of Pharmacy Practice and Translational Research.true1Professor. Chair, Department of Pharmacy Practice and Translational Research.Professor. Chair, Department of Pharmacy Practice and Translational Research.Pharmacy Practice and Translational Researchtrue1ProfessorProfessorAuthorship 962500331830990Hall AE, Engevik MA, Oezguen N, Haag A, Versalovic JMicrobial cell factoriesClC transporter activity modulates histidine catabolism in Lactobacillus reuteri by altering intracellular pH and membrane potential. Microb Cell Fact. 2019 Dec 12; 18(1):212.Microb Cell Fact2019-12-12T00:00:002019ClC transporter activity modulates histidine catabolism in Lactobacillus reuteri by altering intracellular pH and membrane potential.Authorship 1135592Authorship 996995332795635Horvath TD, Haidacher SJ, Oezguen N, Hoch KM, Auchtung JM, Haag AMJournal of microbiological methodsRuggedness testing of liquid chromatography-tandem mass spectrometry system components using microbiome-relevant methods and matrices. J Microbiol Methods. 2020 10; 177:106020.J Microbiol Methods2020-08-11T00:00:002020Ruggedness testing of liquid chromatography-tandem mass spectrometry system components using microbiome-relevant methods and matrices.Authorship 1003210433082337Norsigian CJ, Danhof HA, Brand CK, Oezguen N, Midani FS, Palsson BO, Savidge TC, Britton RA, Spinler JK, Monk JMNPJ systems biology and applicationsSystems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic divergence. NPJ Syst Biol Appl. 2020 10 20; 6(1):31.NPJ Syst Biol Appl2020-10-20T00:00:002020Systems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic divergence.Authorship 1010654233542959Spinler JK, Oezguen N, Runge JK, Luna RA, Karri V, Yang J, Hirschi KDExRNADietary impact of a plant-derived microRNA on the gut microbiome. ExRNA. 2020; 2.ExRNA2020-08-11T00:00:002020Dietary impact of a plant-derived microRNA on the gut microbiome.Authorship 1019487334044101Gonzales-Luna AJ, Spinler JK, Oezguen N, Khan MAW, Danhof HA, Endres BT, Alam MJ, Begum K, Lancaster C, Costa GP, Savidge TC, Hurdle JG, Britton R, Garey KWAnaerobeSystems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation. Anaerobe. 2021 Aug; 70:102387.Anaerobe2021-05-24T00:00:002021Systems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation.Authorship 1028453734439760Luck B, Horvath TD, Engevik KA, Ruan W, Haidacher SJ, Hoch KM, Oezguen N, Spinler JK, Haag AM, Versalovic J, Engevik MABiomoleculesNeurotransmitter Profiles Are Altered in the Gut and Brain of Mice Mono-Associated with Bifidobacterium dentium. Biomolecules. 2021 07 23; 11(8).Biomolecules2021-07-23T00:00:002021Neurotransmitter Profiles Are Altered in the Gut and Brain of Mice Mono-Associated with Bifidobacterium dentium.Authorship 1033531834724447Kellermayer R, Wu Q, Nagy-Szakal D, Queliza K, Ihekweazu FD, Bocchini CE, Magee AR, Oezguen N, Spinler JK, Hollister EB, Shulman RJ, Versalovic J, Luna RA, Savidge TCJournal of pediatric gastroenterology and nutritionFecal Microbiota Transplantation Commonly Failed in Children With Co-Morbidities. J Pediatr Gastroenterol Nutr. 2022 02 01; 74(2):227-235.J Pediatr Gastroenterol Nutr2022-02-01T00:00:002022Fecal Microbiota Transplantation Commonly Failed in Children With Co-Morbidities.Authorship 117871true1ProfessorProfessorAuthorship 1037585435048535Thapa S, Luna RA, Chumpitazi BP, Oezguen N, Abdel-Rahman SM, Garg U, Musaad S, Versalovic J, Kearns GL, Shulman RJClinical and translational sciencePeppermint oil effects on the gut microbiome in children with functional abdominal pain. Clin Transl Sci. 2022 04; 15(4):1036-1049.Clin Transl Sci2022-01-20T00:00:002022Peppermint oil effects on the gut microbiome in children with functional abdominal pain.true1Associate ProfessorAssociate ProfessorAuthorship 1044899935494230Horvath TD, Ihekweazu FD, Haidacher SJ, Ruan W, Engevik KA, Fultz R, Hoch KM, Luna RA, Oezguen N, Spinler JK, Haag AM, Versalovic J, Engevik MAiScienceBacteroides ovatus colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters. iScience. 2022 May 20; 25(5):104158.iScience2022-03-25T00:00:002022Bacteroides ovatus colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters.true1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant ProfessorAuthorship 10601469Authorship 1060152136279598Oezguen N, Yilmaz V, Horvath TD, Akbayir E, Haidacher SJ, Hoch KM, Thapa S, Palacio J, T?rkoglu R, K?rt?nc? M, Engevik MA, Versalovic J, Haag AM, T?z?n EMultiple sclerosis and related disordersSerum 3-phenyllactic acid level is reduced in benign multiple sclerosis and is associated with effector B cell ratios. Mult Scler Relat Disord. 2022 Dec; 68:104239.Mult Scler Relat Disord2022-10-10T00:00:002022Serum 3-phenyllactic acid level is reduced in benign multiple sclerosis and is associated with effector B cell ratios.36352124Horvath TD, Haidacher SJ, Engevik MA, Luck B, Ruan W, Ihekweazu F, Bajaj M, Hoch KM, Oezguen N, Spinler JK, Versalovic J, Haag AMNature protocolsInterrogation of the mammalian gut-brain axis using LC-MS/MS-based targeted metabolomics with in vitro bacterial and organoid cultures and in vivo gnotobiotic mouse models. Nat Protoc. 2023 02; 18(2):490-529.Nat Protoc2022-11-09T00:00:002022Interrogation of the mammalian gut-brain axis using LC-MS/MS-based targeted metabolomics with in vitro bacterial and organoid cultures and in vivo gnotobiotic mouse models.true1Distinguished Emeritus ProfessorDistinguished Emeritus Professor37252854Hotez PJ, Adhikari R, Chen WH, Chen YL, Gillespie P, Islam NY, Keegan B, Tyagi Kundu R, Lee J, Liu Z, Kimata JT, Oezguen N, Pollet J, Poveda C, Razavi K, Ronca SE, Strych U, Thimmiraju SR, Versteeg L, Villar-Mondragon MJ, Wei J, Zhan B, Bottazzi MEExpert review of vaccinesFrom concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access. Expert Rev Vaccines. 2023 Jan-Dec; 22(1):495-500.Expert Rev Vaccines2023-01-01T00:00:002023From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access.Authorship 107254612Authorship 1073395737442546Legere RM, Allegro AR, Affram Y, Silveira BPD, Fridley JL, Wells KM, Oezguen N, Burghardt RC, Wright GA, Pollet J, Bordin AI, Figueiredo P, Leibowitz JL, Cohen NDAmerican journal of veterinary researchEquine bronchial epithelial cells are susceptible to cell entry with a SARS-CoV-2 pseudovirus but reveal low replication efficiency. Am J Vet Res. 2023 Sep 01; 84(9).Am J Vet Res2023-07-18T00:00:002023Equine bronchial epithelial cells are susceptible to cell entry with a SARS-CoV-2 pseudovirus but reveal low replication efficiency.Authorship 1077461537682718Engevik KA, Gonzalez H, Daniels C, Stavert RK, Oezguen N, Engevik MA, Horvath TDSTAR protocolsA high-throughput protocol for measuring solution pH of bacterial cultures using UV-Vis absorption spectrophotometry. STAR Protoc. 2023 Sep 15; 4(3):102540.STAR Protoc2023-09-07T00:00:002023A high-throughput protocol for measuring solution pH of bacterial cultures using UV-Vis absorption spectrophotometry.true1Distinguished Emeritus ProfessorDistinguished Emeritus ProfessorAuthorship 161434Authorship 1089477438369131Patel H, Harris RA, Qian JH, Oezguen N, Watson A, Szigeti RG, Cho S, Ruan W, Britto S, Opekun A, Preidis G, Kellermayer RCellular and molecular gastroenterology and hepatologyGenetic Variation Between Small Bowel and Colon-Predominant Crohn Disease. Cell Mol Gastroenterol Hepatol. 2024 Feb 17.Cell Mol Gastroenterol Hepatol2024-02-17T00:00:002024Genetic Variation Between Small Bowel and Colon-Predominant Crohn Disease.Authorship 1090123138431194Oezguen N, Rider NL, Dowlin M, Singh IThe Journal of pediatricsIdentifying Region-specific Allergy Sensitization Clusters to Optimize Diagnosis and Reduce Costs. J Pediatr. 2024 Feb 29; 113999.J Pediatr2024-02-29T00:00:002024Identifying Region-specific Allergy Sensitization Clusters to Optimize Diagnosis and Reduce Costs.true1ProfessorProfessorAuthorship 204893Authorship 187893Authorship 191409Authorship 230071Authorship 291982Authorship 310683Authorship 1455093Authorship 146309424637601Chumpitazi BP, Hollister EB, Oezguen N, Tsai CM, McMeans AR, Luna RA, Savidge TC, Versalovic J, Shulman RJGut microbesGut microbiota influences low fermentable substrate diet efficacy in children with irritable bowel syndrome. Gut Microbes. 2014 Mar-Apr; 5(2):165-75.Gut Microbes2014-01-27T00:00:002014Gut microbiota influences low fermentable substrate diet efficacy in children with irritable bowel syndrome.24725932Endsley MA, Somasunderam AD, Li G, Oezguen N, Thiviyanathan V, Murray JL, Rubin DH, Hodge TW, O'Brien WA, Lewis B, Ferguson MRVirologyNuclear trafficking of the HIV-1 pre-integration complex depends on the ADAM10 intracellular domain. Virology. 2014 Apr; 454-455:60-6.Virology2014-02-22T00:00:002014Nuclear trafficking of the HIV-1 pre-integration complex depends on the ADAM10 intracellular domain.Authorship 650821Authorship 497756Authorship 702302Authorship 509206Authorship 500612ANTHONYHAAGANTHONY HAAG7891HAAG, ANTHONYAssistant ProfessorAuthorship 734972Authorship 794972Authorship 1548273