JASON ERIKSEN to Anti-Inflammatory Agents, Non-Steroidal
This is a "connection" page, showing publications JASON ERIKSEN has written about Anti-Inflammatory Agents, Non-Steroidal.
Connection Strength
0.438
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NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo. J Clin Invest. 2003 Aug; 112(3):440-9.
Score: 0.175
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Substrate-targeting gamma-secretase modulators. Nature. 2008 Jun 12; 453(7197):925-9.
Score: 0.061
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NSAIDs: small molecules for prevention of Alzheimer's disease or precursors for future drug development? Trends Pharmacol Sci. 2007 Oct; 28(10):536-43.
Score: 0.058
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The non-cyclooxygenase targets of non-steroidal anti-inflammatory drugs, lipoxygenases, peroxisome proliferator-activated receptor, inhibitor of kappa B kinase, and NF kappa B, do not reduce amyloid beta 42 production. J Biol Chem. 2003 Aug 22; 278(34):31825-30.
Score: 0.043
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Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity. J Biol Chem. 2003 Aug 22; 278(34):31831-7.
Score: 0.043
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Abeta42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain. J Biol Chem. 2003 Aug 15; 278(33):30748-54.
Score: 0.043
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Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Abeta42 production. Nat Med. 2005 May; 11(5):545-50.
Score: 0.012