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ROBERT SCHWARTZ

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Collapse Research 
    Collapse research activities and funding
    R01HL089902     (SCHWARTZ, ROBERT JOEL)Apr 1, 2009 - Mar 31, 2014
    NIH
    The Role of Cysteine Rich Protein2 Binding Protein in Cardiovascular Development
    Role: Principal Investigator
    R01HL079628     (SCHWARTZ, ROBERT JOEL)Jan 15, 2005 - Dec 31, 2008
    NIH
    Cardiogenic Gene Switch, Role of SRF Phosphorylation
    Role: Principal Investigator
    R01HL064356     (SCHWARTZ, ROBERT JOEL)Feb 4, 2000 - Jan 31, 2004
    NIH
    RHOA KINASES IN CARDIAC HYPERTROPHY
    Role: Principal Investigator
    R01HL053982     (SCHWARTZ, ROBERT)May 1, 1995 - Apr 30, 1999
    NIH
    HORMONAL REGULATION OF CARDIAC GROWTH AND HYPERTROPHY
    Role: Principal Investigator
    P01HL049953     (SCHWARTZ, ROBERT JOEL)May 20, 1993 - May 31, 2009
    NIH
    GENETIC APPROACHES TO EARLY CARDIAC DEVELOPMENT
    Role: Principal Investigator
    D32PE010012     (SCHWARTZ, ROBERT)Sep 1, 1992 - Aug 31, 1998
    NIH
    DEPARTMENT OF FAMILY MEDICINE
    Role: Principal Investigator
    R01HL045476     (SCHWARTZ, ROBERT)Jul 1, 1990 - Apr 30, 1995
    NIH
    REGULATION OF EMBRYONIC HEART DEVELOPMENT
    Role: Principal Investigator
    R01HL038401     (SCHWARTZ, ROBERT)Jan 8, 1987 - Dec 31, 1991
    NIH
    DIFFERENTIATION OF ACTIN MYOGENESIS
    Role: Principal Investigator
    D15PE012062     (SCHWARTZ, ROBERT)Jul 1, 1980 - Jun 30, 1993
    NIH
    GRANTS FOR GRADUATE TRAINING IN FAMILY MEDICINE
    Role: Principal Investigator
    R01NS015050     (SCHWARTZ, ROBERT)Jan 1, 1979 - Dec 31, 1986
    NIH
    DIFFERENTIATION OF ACTION IN MYOGENESIS
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Reyes-Alcaraz A, Qasim H, Merlinsky E, Fox G, Islam T, Medina B, Schwartz RJ, Craft JW, McConnell BK. A Small Molecule That In Vitro Neutralizes Infection of SARS-CoV-2 and Its Most Infectious Variants, Delta, and Omicron. Biomedicines. 2023 Mar 15; 11(3). PMID: 36979895; PMCID: PMC10046252.
      Citations:    
    2. Prodan N, Ershad F, Reyes-Alcaraz A, Li L, Mistretta B, Gonzalez L, Rao Z, Yu C, Gunaratne PH, Li N, Schwartz RJ, McConnell BK. Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells. iScience. 2022 Nov 18; 25(11):105402. PMID: 36388958; PMCID: PMC9646947.
      Citations:    
    3. Zheng G, He Z, Lu Y, Zhu Q, Jiang Y, Chen D, Lin S, Zhu C, Schwartz R. SRF-derived miR210 and miR30c both repress beating cardiomyocyte formation in the differentiation system of embryoid body. Biochem Biophys Res Commun. 2022 10 20; 626:58-65. PMID: 35970045.
      Citations:    
    4. Xiao S, Liang R, Lucero E, McConnell BK, Chen Z, Chang J, Navran S, Schwartz RJ, Iyer D. STEMIN and YAP5SA synthetic modified mRNAs regenerate and repair infarcted mouse hearts. J Cardiovasc Aging. 2022 Jul; 2(3). PMID: 35891703; PMCID: PMC9311335.
      Citations: 1     
    5. Liang R, Shen X, Wang F, Wang X, DesJarlais A, Syed A, Saba R, Tan Z, Yu F, Ji X, Shrestha S, Ren Y, Yang J, Park Y, Schwartz RJ, Soibam B, McConnell BK, Stewart MD, Kumar A, Liu Y. H19X-encoded miR-322(424)/miR-503 regulates muscle mass by targeting translation initiation factors. J Cachexia Sarcopenia Muscle. 2021 12; 12(6):2174-2186. PMID: 34704401; PMCID: PMC8718088.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Miao L, Lu Y, Nusrat A, Abdelnasser HY, Datta S, Zhou B, Schwartz RJ, Wu M. The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis. Cells. 2021 08 25; 10(9). PMID: 34571841; PMCID: PMC8471136.
      Citations:    
    7. Schwartz RJ, McConnell BK. Response to Zhao and Huang's Commentary Letter, "Conversion of Human Cardiac Progenitor Cells using Reprogramming Factors into Heterogeneous Cardiac Pacemaker-like Cells", regarding our Manuscript: "Conversion of Human Cardiac Progenitor Cells into Cardiac Pacemaker-like Cells". J Mol Cell Cardiol. 2020 04; 141:105-106. PMID: 32224038; PMCID: PMC8063682.
      Citations:    Fields:    Translation:HumansCells
    8. Konop M, Czuwara J, Klodzinska E, Laskowska AK, Sulejczak D, Damps T, Zielenkiewicz U, Brzozowska I, Sureda A, Kowalkowski T, Schwartz RA, Rudnicka L. Evaluation of keratin biomaterial containing silver nanoparticles as a potential wound dressing in full-thickness skin wound model in diabetic mice. J Tissue Eng Regen Med. 2020 02; 14(2):334-346. PMID: 31825159.
      Citations:    
    9. Roberston MJ, Raghunathan S, Potaman VN, Zhang F, Stewart MD, McConnell BK, Schwartz RJ. CRISPR-Cas9-induced IGF1 gene activation as a tool for enhancing muscle differentiation via multiple isoform expression. FASEB J. 2020 01; 34(1):555-570. PMID: 31914652; PMCID: PMC6956731.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    10. Tandon N, Goller K, Wang F, Soibam B, Gagea M, Jain AK, Schwartz RJ, Liu Y. Aberrant expression of embryonic mesendoderm factor MESP1 promotes tumorigenesis. EBioMedicine. 2019 Dec; 50:55-66. PMID: 31761621; PMCID: PMC6921370.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    11. Raghunathan S, Mistretta B, Iyer D, Shi L, Gunaratne PH, Ko G, Schwartz RJ, McConnell BK, Islas JF. Conversion of human cardiac progenitor cells into cardiac pacemaker-like cells. J Mol Cell Cardiol. 2020 01; 138:12-22. PMID: 31678351; PMCID: PMC7035977.
      Citations: 7     Fields:    Translation:HumansCells
    12. Abbasgholizadeh R, Zhang H, Craft JW, Bryan RM, Bark SJ, Briggs JM, Fox RO, Agarkov A, Zimmer WE, Gilbertson SR, Schwartz RJ. Discovery of vascular Rho kinase (ROCK) inhibitory peptides. Exp Biol Med (Maywood). 2019 08; 244(11):940-951. PMID: 31132884; PMCID: PMC6690139.
      Citations:    Fields:    Translation:HumansAnimalsCells
    13. Kim BJ, Zaveri HP, Jordan VK, Hernandez-Garcia A, Jacob DJ, Zamora DL, Yu W, Schwartz RJ, Scott DA. RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects. Dis Model Mech. 2018 08 28; 11(9). PMID: 30061196; PMCID: PMC6176990.
      Citations:    Fields:    Translation:AnimalsCells
    14. Raghunathan S, Reynolds CL, Schwartz RJ, Stewart MD, McConnell BK. C.B-17 SCID mice develop epicardial calcinosis with unaltered cardiac function. Fundam Clin Pharmacol. 2019 Feb; 33(1):25-30. PMID: 29959870; PMCID: PMC6311438.
      Citations:    Fields:    Translation:Animals
    15. Melanson EL, Lyden K, Gibbons E, Gavin KM, Wolfe P, Wierman ME, Schwartz RS, Kohrt WM. Influence of Estradiol Status on Physical Activity in Premenopausal Women. Med Sci Sports Exerc. 2018 08; 50(8):1704-1709. PMID: 29509642; PMCID: PMC6045448.
      Citations: 9     Fields:    Translation:Humans
    16. Roberts WO, Schwartz RS, Garberich RF, Carlson S, Knickelbine T, Schwartz JG, Peichel G, Lesser JR, Wickstrom K, Harris KM. Fifty Men, 3510 Marathons, Cardiac Risk Factors, and Coronary Artery Calcium Scores. Med Sci Sports Exerc. 2017 Dec; 49(12):2369-2373. PMID: 28719492.
      Citations: 5     Fields:    Translation:Humans
    17. Lum HD, Sudore RL, Matlock DD, Juarez-Colunga E, Jones J, Nowels M, Schwartz RS, Kutner JS, Levy CR. A Group Visit Initiative Improves Advance Care Planning Documentation among Older Adults in Primary Care. J Am Board Fam Med. 2017 Jul-Aug; 30(4):480-490. PMID: 28720629; PMCID: PMC5711729.
      Citations: 12     Fields:    Translation:Humans
    18. Valenzuela N, Soibam B, Li L, Wang J, Byers LA, Liu Y, Schwartz RJ, Stewart MD. HIRA deficiency in muscle fibers causes hypertrophy and susceptibility to oxidative stress. J Cell Sci. 2017 Aug 01; 130(15):2551-2563. PMID: 28600325.
      Citations: 6     Fields:    Translation:Animals
    19. Islas JF, Schwartz RJ, Birla RK, Mohamed MA. Electrical Stimulation of Artificial Heart Muscle: A Look Into the Electrophysiologic and Genetic Implications. ASAIO J. 2017 May/Jun; 63(3):333-341. PMID: 28459744; PMCID: PMC5469367.
      Citations: 3     Fields:    Translation:AnimalsCells
    20. Roberts WO, Schwartz RS, Kraus SM, Schwartz JG, Peichel G, Garberich RF, Lesser JR, Oesterle SN, Wickstrom KK, Knickelbine T, Harris KM. Long-Term Marathon Running Is Associated with Low Coronary Plaque Formation in Women. Med Sci Sports Exerc. 2017 04; 49(4):641-645. PMID: 27824692.
      Citations: 8     Fields:    Translation:Humans
    21. Liu Y, Chen L, Diaz AD, Benham A, Xu X, Wijaya CS, Fa'ak F, Luo W, Soibam B, Azares A, Yu W, Lyu Q, Stewart MD, Gunaratne P, Cooney A, McConnell BK, Schwartz RJ. Mesp1 Marked Cardiac Progenitor Cells Repair Infarcted Mouse Hearts. Sci Rep. 2016 08 19; 6:31457. PMID: 27538477; PMCID: PMC4990963.
      Citations: 11     Fields:    Translation:AnimalsCells
    22. Shen X, Soibam B, Benham A, Xu X, Chopra M, Peng X, Yu W, Bao W, Liang R, Azares A, Liu P, Gunaratne PH, Mercola M, Cooney AJ, Schwartz RJ, Liu Y. miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification. Proc Natl Acad Sci U S A. 2016 08 23; 113(34):9551-6. PMID: 27512039; PMCID: PMC5003281.
      Citations: 34     Fields:    Translation:AnimalsCells
    23. Liu Y, Mercola M, Schwartz RJ. The All-Chemical Approach: A Solution for Converting Fibroblasts Into Myocytes. Circ Res. 2016 08 05; 119(4):505-7. PMID: 27492839; PMCID: PMC4987128.
      Citations:    Fields:    Translation:Cells
    24. Valenzuela N, Fan Q, Fa'ak F, Soibam B, Nagandla H, Liu Y, Schwartz RJ, McConnell BK, Stewart MD. Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis. Dis Model Mech. 2016 Mar; 9(3):335-45. PMID: 26935106; PMCID: PMC4833330.
      Citations: 9     Fields:    Translation:AnimalsCells
    25. Stewart MD, Lopez S, Nagandla H, Soibam B, Benham A, Nguyen J, Valenzuela N, Wu HJ, Burns AR, Rasmussen TL, Tucker HO, Schwartz RJ. Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy, internalization of nuclei and myofibrillar disarray. Dis Model Mech. 2016 Mar; 9(3):347-59. PMID: 26935107; PMCID: PMC4833328.
      Citations: 12     Fields:    Translation:AnimalsCells
    26. Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD. Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 01; 410(1):86-97. PMID: 26688546.
      Citations: 15     Fields:    Translation:AnimalsCells
    27. Shea KL, Gavin KM, Melanson EL, Gibbons E, Stavros A, Wolfe P, Kittelson JM, Vondracek SF, Schwartz RS, Wierman ME, Kohrt WM. Body composition and bone mineral density after ovarian hormone suppression with or without estradiol treatment. Menopause. 2015 Oct; 22(10):1045-52. PMID: 25783468; PMCID: PMC4760356.
      Citations: 26     Fields:    Translation:Humans
    28. Melanson EL, Gavin KM, Shea KL, Wolfe P, Wierman ME, Schwartz RS, Kohrt WM. Regulation of energy expenditure by estradiol in premenopausal women. J Appl Physiol (1985). 2015 Nov 01; 119(9):975-81. PMID: 26338457; PMCID: PMC4628992.
      Citations: 23     Fields:    Translation:Humans
    29. Schwartz RS, Satran D, Lesser JR, Sharkey SW, Garberich RF, Solie CJ, Longe TF, Flygenring BP, Lin D, Larson DM, Henry TD, Stark MM. "No culprit" ST-elevation myocardial infarction: role of cardiac magnetic resonance imaging. Crit Pathw Cardiol. 2014 Dec; 13(4):135-40. PMID: 25396289.
      Citations:    Fields:    Translation:Humans
    30. Liu Y, Kaneda R, Leja TW, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz RJ, Barahona M, Schneider MD. Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells. Stem Cells. 2014 Jun; 32(6):1515-26. PMID: 24585688; PMCID: PMC4260090.
      Citations: 7     Fields:    Translation:AnimalsCells
    31. Reineke EL, Benham A, Soibam B, Stashi E, Taegtmeyer H, Entman ML, Schwartz RJ, O'Malley BW. Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function. J Biol Chem. 2014 Jun 20; 289(25):17721-31. PMID: 24811170; PMCID: PMC4067206.
      Citations: 10     Fields:    Translation:Animals
    32. Casey BA, Kohrt WM, Schwartz RS, Van Pelt RE. Subcutaneous adipose tissue insulin resistance is associated with visceral adiposity in postmenopausal women. Obesity (Silver Spring). 2014 Jun; 22(6):1458-63. PMID: 24420961; PMCID: PMC4037374.
      Citations: 1     Fields:    Translation:HumansCells
    33. Craft JW, Zhang H, Charendoff MN, Mindrebo JT, Schwartz RJ, Briggs JM. Associations between the Rho kinase-1 catalytic and PH domain regulatory unit. J Mol Graph Model. 2013 Nov; 46:74-82. PMID: 24149321.
      Citations: 2     Fields:    Translation:HumansCells
    34. Wang J, Bai Y, Li H, Greene SB, Klysik E, Yu W, Schwartz RJ, Williams TJ, Martin JF. MicroRNA-17-92, a direct Ap-2a transcriptional target, modulates T-box factor activity in orofacial clefting. PLoS Genet. 2013; 9(9):e1003785. PMID: 24068957; PMCID: PMC3777996.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    35. Li Y, Yu W, Cooney AJ, Schwartz RJ, Liu Y. Brief report: Oct4 and canonical Wnt signaling regulate the cardiac lineage factor Mesp1 through a Tcf/Lef-Oct4 composite element. Stem Cells. 2013 Jun; 31(6):1213-7. PMID: 23417899.
      Citations: 17     Fields:    Translation:AnimalsCells
    36. Liu Y, Schwartz RJ. Transient Mesp1 expression: a driver of cardiac cell fate determination. Transcription. 2013 May-Jun; 4(3):92-6. PMID: 23584093; PMCID: PMC4042590.
      Citations: 5     Fields:    Translation:HumansCells
    37. Min JK, Leipsic J, Pencina MJ, Berman DS, Koo BK, van Mieghem C, Erglis A, Lin FY, Dunning AM, Apruzzese P, Budoff MJ, Cole JH, Jaffer FA, Leon MB, Malpeso J, Mancini GB, Park SJ, Schwartz RS, Shaw LJ, Mauri L. Diagnostic accuracy of fractional flow reserve from anatomic CT angiography. JAMA. 2012 Sep 26; 308(12):1237-45. PMID: 22922562; PMCID: PMC4281479.
      Citations:    
    38. Liu Y, Schwartz RJ. Reprogrammed cardiac fibroblasts to the rescue of heart failure. Circ Res. 2012 Sep 14; 111(7):831-2. PMID: 22982872.
      Citations: 1     Fields:    
    39. Stewart MD, Deng JM, Stewart CA, Mullen RD, Wang Y, Lopez S, Serna MK, Huang CC, Janovick JA, Pask AJ, Schwartz RJ, Conn PM, Behringer RR. Mice harboring Gnrhr E90K, a mutation that causes protein misfolding and hypogonadotropic hypogonadism in humans, exhibit testis size reduction and ovulation failure. Mol Endocrinol. 2012 Nov; 26(11):1847-56. PMID: 22918878; PMCID: PMC3487620.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    40. Schwartz RJ, Yeh ET. Weighing in on heart failure: the role of SERCA2a SUMOylation. Circ Res. 2012 Jan 20; 110(2):198-9. PMID: 22267837.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    41. Min JK, Berman DS, Budoff MJ, Jaffer FA, Leipsic J, Leon MB, Mancini GB, Mauri L, Schwartz RS, Shaw LJ. Rationale and design of the DeFACTO (Determination of Fractional Flow Reserve by Anatomic Computed Tomographic AngiOgraphy) study. J Cardiovasc Comput Tomogr. 2011 Sep-Oct; 5(5):301-9. PMID: 21930103.
      Citations: 32     Fields:    Translation:HumansCTClinical Trials
    42. American College of Cardiology Foundation Task Force on Expert Consensus Documents, Mark DB, Berman DS, Budoff MJ, Carr JJ, Gerber TC, Hecht HS, Hlatky MA, Hodgson JM, Lauer MS, Miller JM, Morin RL, Mukherjee D, Poon M, Rubin GD, Schwartz RS. ACCF/ACR/AHA/NASCI/SAIP/SCAI/SCCT 2010 expert consensus document on coronary computed tomographic angiography: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. Circulation. 2010 Jun 08; 121(22):2509-43. PMID: 20479158.
      Citations: 52     Fields:    Translation:Humans
    43. Holmes DR, Schwartz RS. Left atrial appendage occlusion eliminates the need for warfarin. Circulation. 2009 Nov 10; 120(19):1919-26; discussion 1926. PMID: 19901202.
      Citations: 8     Fields:    Translation:Humans
    44. Kohrt WM, Barry DW, Schwartz RS. Muscle forces or gravity: what predominates mechanical loading on bone? Med Sci Sports Exerc. 2009 Nov; 41(11):2050-5. PMID: 19812511; PMCID: PMC3037021.
      Citations: 61     Fields:    Translation:HumansCells
    45. Wilson GJ, Nakazawa G, Schwartz RS, Huibregtse B, Poff B, Herbst TJ, Baim DS, Virmani R. Comparison of inflammatory response after implantation of sirolimus- and paclitaxel-eluting stents in porcine coronary arteries. Circulation. 2009 Jul 14; 120(2):141-9, 1-2. PMID: 19564562.
      Citations: 48     Fields:    Translation:AnimalsCells
    46. Haudek SB, Gupta D, Dewald O, Schwartz RJ, Wei L, Trial J, Entman ML. Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation. Cardiovasc Res. 2009 Aug 01; 83(3):511-8. PMID: 19406912; PMCID: PMC2709463.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    47. Niu Z, Iyer D, Conway SJ, Martin JF, Ivey K, Srivastava D, Nordheim A, Schwartz RJ. Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17824-9. PMID: 19004760; PMCID: PMC2584699.
      Citations: 63     Fields:    Translation:AnimalsCells
    48. Henry TD, Schwartz RS, Hirsch AT. "POBA Plus": will the balloon regain its luster? Circulation. 2008 Sep 23; 118(13):1309-11. PMID: 18809805.
      Citations: 1     Fields:    Translation:Humans
    49. Niu Z, Li A, Zhang SX, Schwartz RJ. Serum response factor micromanaging cardiogenesis. Curr Opin Cell Biol. 2007 Dec; 19(6):618-27. PMID: 18023168; PMCID: PMC2735128.
      Citations: 62     Fields:    Translation:HumansAnimals
    50. Hara H, Jones TK, Ladich ER, Virmani R, Auth DC, Eichinger JE, Sommer RJ, Van Tassel RA, Schwartz RS. Patent foramen ovale closure by radiofrequency thermal coaptation: first experience in the porcine model and healing mechanisms over time. Circulation. 2007 Aug 07; 116(6):648-53. PMID: 17664371.
      Citations: 4     Fields:    Translation:Animals
    51. Zhu L, Harutyunyan KG, Peng JL, Wang J, Schwartz RJ, Belmont JW. Identification of a novel role of ZIC3 in regulating cardiac development. Hum Mol Genet. 2007 Jul 15; 16(14):1649-60. PMID: 17468179.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    52. Hara H, Pedersen WR, Ladich E, Mooney M, Virmani R, Nakamura M, Feldman T, Schwartz RS. Percutaneous balloon aortic valvuloplasty revisited: time for a renaissance? Circulation. 2007 Mar 27; 115(12):e334-8. PMID: 17389271.
      Citations: 15     Fields:    Translation:Humans
    53. Liu Y, Asakura M, Inoue H, Nakamura T, Sano M, Niu Z, Chen M, Schwartz RJ, Schneider MD. Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):3859-64. PMID: 17360443; PMCID: PMC1820674.
      Citations: 65     Fields:    Translation:AnimalsCells
    54. Hara H, Virmani R, Ladich E, Mackey-Bojack S, Titus JL, Karnicki K, Stewart M, Pelzel JM, Schwartz RS. Patent foramen ovale: standards for a preclinical model of prevalence, structure, and histopathologic comparability to human hearts. Catheter Cardiovasc Interv. 2007 Feb 01; 69(2):266-73. PMID: 17173313.
      Citations: 4     Fields:    Translation:HumansAnimals
    55. Chang DF, Belaguli NS, Chang J, Schwartz RJ. LIM-only protein, CRP2, switched on smooth muscle gene activity in adult cardiac myocytes. Proc Natl Acad Sci U S A. 2007 Jan 02; 104(1):157-62. PMID: 17185421; PMCID: PMC1765427.
      Citations: 20     Fields:    Translation:AnimalsCells
    56. Schwartz RS. The politics and promise of stem-cell research. N Engl J Med. 2006 Sep 21; 355(12):1189-91. PMID: 16990380.
      Citations: 5     Fields:    Translation:HumansCells
    57. Iyer D, Chang D, Marx J, Wei L, Olson EN, Parmacek MS, Balasubramanyam A, Schwartz RJ. Serum response factor MADS box serine-162 phosphorylation switches proliferation and myogenic gene programs. Proc Natl Acad Sci U S A. 2006 Mar 21; 103(12):4516-21. PMID: 16537394; PMCID: PMC1450203.
      Citations: 31     Fields:    Translation:AnimalsCells
    58. Stone GW, Reifart NJ, Moussa I, Hoye A, Cox DA, Colombo A, Baim DS, Teirstein PS, Strauss BH, Selmon M, Mintz GS, Katoh O, Mitsudo K, Suzuki T, Tamai H, Grube E, Cannon LA, Kandzari DE, Reisman M, Schwartz RS, Bailey S, Dangas G, Mehran R, Abizaid A, Moses JW, Leon MB, Serruys PW. Percutaneous recanalization of chronically occluded coronary arteries: a consensus document: part II. Circulation. 2005 Oct 18; 112(16):2530-7. PMID: 16230504.
      Citations: 60     Fields:    Translation:Humans
    59. Stone GW, Kandzari DE, Mehran R, Colombo A, Schwartz RS, Bailey S, Moussa I, Teirstein PS, Dangas G, Baim DS, Selmon M, Strauss BH, Tamai H, Suzuki T, Mitsudo K, Katoh O, Cox DA, Hoye A, Mintz GS, Grube E, Cannon LA, Reifart NJ, Reisman M, Abizaid A, Moses JW, Leon MB, Serruys PW. Percutaneous recanalization of chronically occluded coronary arteries: a consensus document: part I. Circulation. 2005 Oct 11; 112(15):2364-72. PMID: 16216980.
      Citations: 94     Fields:    Translation:HumansAnimals
    60. Chi X, Chatterjee PK, Wilson W, Zhang SX, Demayo FJ, Schwartz RJ. Complex cardiac Nkx2-5 gene expression activated by noggin-sensitive enhancers followed by chamber-specific modules. Proc Natl Acad Sci U S A. 2005 Sep 20; 102(38):13490-5. PMID: 16150722; PMCID: PMC1224629.
      Citations: 14     Fields:    Translation:AnimalsCells
    61. Niu Z, Yu W, Zhang SX, Barron M, Belaguli NS, Schneider MD, Parmacek M, Nordheim A, Schwartz RJ. Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets. J Biol Chem. 2005 Sep 16; 280(37):32531-8. PMID: 15929941.
      Citations: 56     Fields:    Translation:AnimalsCells
    62. Takamoto N, You LR, Moses K, Chiang C, Zimmer WE, Schwartz RJ, DeMayo FJ, Tsai MJ, Tsai SY. COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development. 2005 May; 132(9):2179-89. PMID: 15829524.
      Citations: 70     Fields:    Translation:Animals
    63. Ahn Y, Jeong MH, Schwartz RS. Changing paradigm for neointimal cell origin: is restenosis a blood-borne disease? Catheter Cardiovasc Interv. 2005 Apr; 64(4):468-70. PMID: 15789396.
      Citations:    Fields:    Translation:HumansAnimalsCells
    64. Zhang SX, Garcia-Gras E, Wycuff DR, Marriot SJ, Kadeer N, Yu W, Olson EN, Garry DJ, Parmacek MS, Schwartz RJ. Identification of direct serum-response factor gene targets during Me2SO-induced P19 cardiac cell differentiation. J Biol Chem. 2005 May 13; 280(19):19115-26. PMID: 15699019.
      Citations: 43     Fields:    Translation:AnimalsCells
    65. Vlahopoulos S, Zimmer WE, Jenster G, Belaguli NS, Balk SP, Brinkmann AO, Lanz RB, Zoumpourlis VC, Schwartz RJ. Recruitment of the androgen receptor via serum response factor facilitates expression of a myogenic gene. J Biol Chem. 2005 Mar 04; 280(9):7786-92. PMID: 15623502.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    66. Barron MR, Belaguli NS, Zhang SX, Trinh M, Iyer D, Merlo X, Lough JW, Parmacek MS, Bruneau BG, Schwartz RJ. Serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for Tbx genes. J Biol Chem. 2005 Mar 25; 280(12):11816-28. PMID: 15591049.
      Citations: 15     Fields:    Translation:AnimalsCells
    67. Schwartz RS, Edelman ER, Carter A, Chronos NA, Rogers C, Robinson KA, Waksman R, Machan L, Weinberger J, Wilensky RL, Goode JL, Hottenstein OD, Zuckerman BD, Virmani R. Preclinical evaluation of drug-eluting stents for peripheral applications: recommendations from an expert consensus group. Circulation. 2004 Oct 19; 110(16):2498-505. PMID: 15492330.
      Citations: 15     Fields:    Translation:Animals
    68. Lesser JR, Knickelbine T, Chavez I, Lindberg J, Schwartz RS. Images in cardiovascular medicine. Ruptured plaque visualization by noninvasive coronary computed tomography angiography. Circulation. 2004 Sep 21; 110(12):e311-2. PMID: 15381663.
      Citations:    Fields:    Translation:Humans
    69. Wang J, Feng XH, Schwartz RJ. SUMO-1 modification activated GATA4-dependent cardiogenic gene activity. J Biol Chem. 2004 Nov 19; 279(47):49091-8. PMID: 15337742.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    70. Xu H, Morishima M, Wylie JN, Schwartz RJ, Bruneau BG, Lindsay EA, Baldini A. Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract. Development. 2004 Jul; 131(13):3217-27. PMID: 15175244.
      Citations: 141     Fields:    Translation:AnimalsCells
    71. Oh H, Chi X, Bradfute SB, Mishina Y, Pocius J, Michael LH, Behringer RR, Schwartz RJ, Entman ML, Schneider MD. Cardiac muscle plasticity in adult and embryo by heart-derived progenitor cells. Ann N Y Acad Sci. 2004 May; 1015:182-9. PMID: 15201159.
      Citations: 42     Fields:    Translation:HumansCells
    72. Wei L, Taffet GE, Khoury DS, Bo J, Li Y, Yatani A, Delaughter MC, Klevitsky R, Hewett TE, Robbins J, Michael LH, Schneider MD, Entman ML, Schwartz RJ. Disruption of Rho signaling results in progressive atrioventricular conduction defects while ventricular function remains preserved. FASEB J. 2004 May; 18(7):857-9. PMID: 15033930.
      Citations: 20     Fields:    Translation:AnimalsCells
    73. Tetzlaff MT, Yu W, Li M, Zhang P, Finegold M, Mahon K, Harper JW, Schwartz RJ, Elledge SJ. Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein. Proc Natl Acad Sci U S A. 2004 Mar 09; 101(10):3338-45. PMID: 14766969; PMCID: PMC373463.
      Citations: 126     Fields:    Translation:AnimalsCells
    74. Brown CO, Chi X, Garcia-Gras E, Shirai M, Feng XH, Schwartz RJ. The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer. J Biol Chem. 2004 Mar 12; 279(11):10659-69. PMID: 14662776.
      Citations: 67     Fields:    Translation:AnimalsCells
    75. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Airaksinen KE, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang IK, Koenig W, Lodder RA, March K, Demirovic J, Navab M, Priori SG, Rekhter MD, Bahr R, Grundy SM, Mehran R, Colombo A, Boerwinkle E, Ballantyne C, Insull W, Schwartz RS, Vogel R, Serruys PW, Hansson GK, Faxon DP, Kaul S, Drexler H, Greenland P, Muller JE, Virmani R, Ridker PM, Zipes DP, Shah PK, Willerson JT. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. Circulation. 2003 Oct 14; 108(15):1772-8. PMID: 14557340.
      Citations: 303     Fields:    Translation:HumansAnimalsPHPublic Health
    76. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Juhani Airaksinen KE, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang IK, Koenig W, Lodder RA, March K, Demirovic J, Navab M, Priori SG, Rekhter MD, Bahr R, Grundy SM, Mehran R, Colombo A, Boerwinkle E, Ballantyne C, Insull W, Schwartz RS, Vogel R, Serruys PW, Hansson GK, Faxon DP, Kaul S, Drexler H, Greenland P, Muller JE, Virmani R, Ridker PM, Zipes DP, Shah PK, Willerson JT. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation. 2003 Oct 07; 108(14):1664-72. PMID: 14530185.
      Citations: 730     Fields:    Translation:Humans
    77. Bayes-Genis A, Schwartz RS, Bale LK, Conover CA. Effects of insulin-like growth factor-I on cultured human coronary artery smooth muscle cells. Growth Horm IGF Res. 2003 Oct; 13(5):246-53. PMID: 12932745.
      Citations: 2     Fields:    Translation:HumansCells
    78. Mohapatra B, Jimenez S, Lin JH, Bowles KR, Coveler KJ, Marx JG, Chrisco MA, Murphy RT, Lurie PR, Schwartz RJ, Elliott PM, Vatta M, McKenna W, Towbin JA, Bowles NE. Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis. Mol Genet Metab. 2003 Sep-Oct; 80(1-2):207-15. PMID: 14567970.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    79. Chang J, Wei L, Otani T, Youker KA, Entman ML, Schwartz RJ. Inhibitory cardiac transcription factor, SRF-N, is generated by caspase 3 cleavage in human heart failure and attenuated by ventricular unloading. Circulation. 2003 Jul 29; 108(4):407-13. PMID: 12874181.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    80. Lesser JR, Johnson K, Lindberg JL, Reed J, Tadavarthy SM, Virmani R, Schwartz RS. Images in cardiovascular medicine. Myocardial rupture, microvascular obstruction, and infarct expansion: elucidation by cardiac magnetic resonance. Circulation. 2003 Jul 08; 108(1):116-7. PMID: 12847055.
      Citations: 3     Fields:    Translation:Humans
    81. Iyer D, Belaguli N, Rowan BG, Wei L, Weigel NL, Booth FW, Epstein HF, Schwartz RJ, Balasubramanyam A, Fl?ck M. Novel phosphorylation target in the serum response factor MADS box regulates alpha-actin transcription. Biochemistry. 2003 Jun 24; 42(24):7477-86. PMID: 12809504.
      Citations: 11     Fields:    Translation:AnimalsCells
    82. Chi X, Zhang SX, Yu W, DeMayo FJ, Rosenberg SM, Schwartz RJ. Expression of Nkx2-5-GFP bacterial artificial chromosome transgenic mice closely resembles endogenous Nkx2-5 gene activity. Genesis. 2003 Apr; 35(4):220-6. PMID: 12717733.
      Citations: 8     Fields:    Translation:AnimalsCells
    83. Rodriguez-Porcel M, Lerman A, Herrmann J, Schwartz RS, Sawamura T, Condorelli M, Napoli C, Lerman LO. Hypertension exacerbates the effect of hypercholesterolemia on the myocardial microvasculature. Cardiovasc Res. 2003 Apr 01; 58(1):213-21. PMID: 12667964.
      Citations: 16     Fields:    Translation:AnimalsCells
    84. Chang DF, Belaguli NS, Iyer D, Roberts WB, Wu SP, Dong XR, Marx JG, Moore MS, Beckerle MC, Majesky MW, Schwartz RJ. Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors. Dev Cell. 2003 Jan; 4(1):107-18. PMID: 12530967.
      Citations: 104     Fields:    Translation:AnimalsCells
    85. Fiorotto ML, Schwartz RJ, Delaughter MC. Persistent IGF-I overexpression in skeletal muscle transiently enhances DNA accretion and growth. FASEB J. 2003 Jan; 17(1):59-60. PMID: 12528713.
      Citations: 20     Fields:    Translation:HumansAnimals
    86. Karnik SK, Brooke BS, Bayes-Genis A, Sorensen L, Wythe JD, Schwartz RS, Keating MT, Li DY. A critical role for elastin signaling in vascular morphogenesis and disease. Development. 2003 Jan; 130(2):411-23. PMID: 12466207.
      Citations: 174     Fields:    Translation:HumansAnimalsCells
    87. Stringer JL, Belaguli NS, Iyer D, Schwartz RJ, Balasubramanyam A. Developmental expression of serum response factor in the rat central nervous system. Brain Res Dev Brain Res. 2002 Sep 20; 138(1):81-6. PMID: 12234660.
      Citations: 9     Fields:    Translation:AnimalsCells
    88. Wei L, Imanaka-Yoshida K, Wang L, Zhan S, Schneider MD, DeMayo FJ, Schwartz RJ. Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation. Development. 2002 Apr; 129(7):1705-14. PMID: 11923206.
      Citations: 32     Fields:    Translation:Animals
    89. Schwartz RS. A new element in the mechanism of asthma. N Engl J Med. 2002 Mar 14; 346(11):857-8. PMID: 11893801.
      Citations: 3     Fields:    Translation:AnimalsCells
    90. Panetta CJ, Miyauchi K, Berry D, Simari RD, Holmes DR, Schwartz RS, Caplice NM. A tissue-engineered stent for cell-based vascular gene transfer. Hum Gene Ther. 2002 Feb 10; 13(3):433-41. PMID: 11860710.
      Citations: 6     Fields:    Translation:Animals
    91. Draghia-Akli R, Malone PB, Hill LA, Ellis KM, Schwartz RJ, Nordstrom JL. Enhanced animal growth via ligand-regulated GHRH myogenic-injectable vectors. FASEB J. 2002 Mar; 16(3):426-8. PMID: 11790726.
      Citations: 4     Fields:    Translation:AnimalsCells
    92. Schwartz RS, Curfman GD. Can the heart repair itself? N Engl J Med. 2002 Jan 03; 346(1):2-4. PMID: 11777996.
      Citations: 8     Fields:    Translation:HumansCells
    93. Hirschi KK, Lai L, Belaguli NS, Dean DA, Schwartz RJ, Zimmer WE. Transforming growth factor-beta induction of smooth muscle cell phenotpye requires transcriptional and post-transcriptional control of serum response factor. J Biol Chem. 2002 Feb 22; 277(8):6287-95. PMID: 11741973; PMCID: PMC4421896.
      Citations: 31     Fields:    Translation:AnimalsCells
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